Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1zy4_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 4.A N GLU 73.A OE2 no hydrogen 2.831 N/A TYR 4.A OH GLU 10.A OE1 no hydrogen 2.711 N/A SER 6.A N LEU 2.A O no hydrogen 3.057 N/A SER 6.A OG LEU 2.A O no hydrogen 3.128 N/A SER 6.A OG ARG 3.A O no hydrogen 3.257 N/A SER 6.A OG ASP 7.A OD1 no hydrogen 3.138 N/A ASP 7.A N ARG 3.A O no hydrogen 2.854 N/A PHE 8.A N TYR 4.A O no hydrogen 3.131 N/A GLU 9.A N ARG 26.A O no hydrogen 2.885 N/A ILE 11.A N LYS 24.A O no hydrogen 2.816 N/A ALA 12.A N LYS 24.A O no hydrogen 3.270 N/A LEU 14.A N VAL 22.A O no hydrogen 2.662 N/A GLY 15.A N VAL 22.A O no hydrogen 3.072 N/A GLY 17.A N GLY 20.A O no hydrogen 2.772 N/A GLN 21.A N LYS 38.A O no hydrogen 3.262 N/A VAL 22.A N GLY 15.A O no hydrogen 2.799 N/A VAL 23.A N ILE 36.A O no hydrogen 2.964 N/A LYS 24.A N ALA 12.A O no hydrogen 2.704 N/A ALA 25.A N TYR 34.A O no hydrogen 3.028 N/A ARG 26.A N GLU 9.A O no hydrogen 2.861 N/A ARG 26.A NE SER 31.A O no hydrogen 2.811 N/A ASN 27.A N ARG 32.A O no hydrogen 2.886 N/A ALA 28.A N ASP 7.A O no hydrogen 2.711 N/A SER 31.A N ASN 27.A O no hydrogen 2.807 N/A ARG 32.A N ASP 30.A OD2 no hydrogen 2.801 N/A TYR 34.A N ALA 25.A O no hydrogen 2.923 N/A TYR 34.A OH ASP 30.A OD1 no hydrogen 2.588 N/A ALA 35.A N MET 88.A O no hydrogen 2.876 N/A ILE 36.A N VAL 23.A O no hydrogen 2.811 N/A LYS 37.A N ILE 86.A O no hydrogen 2.843 N/A LYS 38.A N GLN 21.A O no hydrogen 2.854 N/A LYS 38.A NZ GLU 10.A OE1 no hydrogen 2.608 N/A LYS 38.A NZ GLN 21.A OE1 no hydrogen 2.739 N/A ILE 39.A N LEU 84.A O no hydrogen 2.926 N/A ARG 40.A N PHE 19.A O no hydrogen 2.657 N/A HIS 41.A N SER 82.A O no hydrogen 3.001 N/A THR 42.A N HIS 41.A ND1 no hydrogen 2.796 N/A LYS 45.A N THR 42.A OG1 no hydrogen 3.118 N/A LEU 46.A N THR 42.A O no hydrogen 2.891 N/A SER 47.A N GLU 43.A O no hydrogen 2.881 N/A SER 47.A OG GLU 44.A O no hydrogen 2.725 N/A THR 48.A N LYS 45.A O no hydrogen 3.191 N/A THR 48.A OG1 LYS 45.A O no hydrogen 2.570 N/A ILE 49.A N LEU 46.A O no hydrogen 2.899 N/A VAL 53.A N ILE 49.A O no hydrogen 2.947 N/A MET 54.A N LEU 50.A O no hydrogen 2.858 N/A LEU 55.A N SER 51.A O no hydrogen 2.931 N/A LEU 56.A N GLU 52.A O no hydrogen 2.994 N/A ALA 57.A N VAL 53.A O no hydrogen 3.003 N/A SER 58.A N LEU 55.A O no hydrogen 2.881 N/A SER 58.A OG LEU 55.A O no hydrogen 2.660 N/A LEU 59.A N LEU 56.A O no hydrogen 3.116 N/A ASN 60.A N TYR 125.A OH no hydrogen 2.998 N/A VAL 64.A N HIS 61.A O no hydrogen 3.152 N/A VAL 65.A N ILE 151.A O no hydrogen 2.836 N/A ARG 66.A N GLU 89.A OE1 no hydrogen 3.027 N/A TYR 68.A N GLN 87.A O no hydrogen 2.791 N/A ALA 69.A N GLN 87.A O no hydrogen 3.432 N/A TRP 71.A N PHE 85.A O no hydrogen 2.990 N/A TRP 71.A NE1 GLU 73.A OE2 no hydrogen 2.821 N/A GLU 73.A N THR 83.A O no hydrogen 2.876 N/A ARG 74.A NE GLU 43.A OE1 no hydrogen 3.359 N/A ARG 74.A NE GLU 43.A OE2 no hydrogen 2.726 N/A ARG 74.A NH2 GLU 43.A OE1 no hydrogen 2.784 N/A ARG 75.A NH1 GLU 73.A OE1 no hydrogen 2.899 N/A ARG 75.A NH2 GLU 73.A OE1 no hydrogen 2.868 N/A LYS 80.A NZ ARG 75.A O no hydrogen 2.747 N/A LYS 80.A NZ LYS 81.A O no hydrogen 3.222 N/A SER 82.A N HIS 41.A O no hydrogen 2.881 N/A SER 82.A OG GLU 43.A OE2 no hydrogen 2.532 N/A THR 83.A N GLU 73.A O no hydrogen 3.004 N/A LEU 84.A N ILE 39.A O no hydrogen 2.840 N/A PHE 85.A N TRP 71.A O no hydrogen 2.745 N/A ILE 86.A N LYS 37.A O no hydrogen 2.764 N/A GLN 87.A N ALA 69.A O no hydrogen 2.741 N/A MET 88.A N ALA 35.A O no hydrogen 2.748 N/A GLU 89.A N ARG 66.A O no hydrogen 2.914 N/A THR 95.A N ASP 98.A OD2 no hydrogen 2.885 N/A THR 95.A OG1 ASP 98.A OD2 no hydrogen 3.308 N/A LEU 96.A N ILE 141.A O no hydrogen 2.778 N/A TYR 97.A N THR 95.A OG1 no hydrogen 3.173 N/A TYR 97.A N PRO 138.A O no hydrogen 3.306 N/A ASP 98.A N THR 95.A OG1 no hydrogen 3.424 N/A LEU 99.A N THR 95.A O no hydrogen 3.018 N/A ILE 100.A N LEU 96.A O no hydrogen 2.770 N/A HIS 101.A N TYR 97.A O no hydrogen 3.059 N/A SER 102.A N LEU 99.A O no hydrogen 3.351 N/A SER 102.A OG ASP 98.A O no hydrogen 2.992 N/A GLU 103.A N LEU 99.A O no hydrogen 3.062 N/A GLN 107.A N ASN 104.A O no hydrogen 3.128 N/A GLN 108.A N LEU 105.A O no hydrogen 2.880 N/A GLN 108.A NE2 GLU 103.A O no hydrogen 3.115 N/A GLN 108.A NE2 GLU 103.A OE1 no hydrogen 3.247 N/A TYR 112.A N GLN 108.A O no hydrogen 2.927 N/A TYR 112.A OH GLU 229.A OE2 no hydrogen 2.779 N/A TRP 113.A N ARG 109.A O no hydrogen 3.182 N/A ARG 114.A N ASP 110.A O no hydrogen 3.054 N/A ARG 114.A NE GLU 111.A OE2 no hydrogen 3.171 N/A ARG 114.A NH1 GLU 111.A OE1 no hydrogen 2.576 N/A ARG 114.A NH1 ARG 147.A O no hydrogen 2.956 N/A ARG 114.A NH2 ARG 147.A O no hydrogen 3.101 N/A LEU 115.A N GLU 111.A O no hydrogen 2.956 N/A PHE 116.A N TYR 112.A O no hydrogen 2.917 N/A ARG 117.A N TRP 113.A O no hydrogen 2.885 N/A ARG 117.A NH1 PRO 257.A O no hydrogen 2.695 N/A GLN 118.A N ARG 114.A O no hydrogen 3.053 N/A GLN 118.A NE2 ASN 148.A OD1 no hydrogen 2.966 N/A ILE 119.A N LEU 115.A O no hydrogen 2.964 N/A LEU 120.A N PHE 116.A O no hydrogen 3.016 N/A GLU 121.A N ARG 117.A O no hydrogen 2.912 N/A ALA 122.A N GLN 118.A O no hydrogen 2.881 N/A LEU 123.A N ILE 119.A O no hydrogen 2.791 N/A SER 124.A N LEU 120.A O no hydrogen 2.822 N/A SER 124.A OG LEU 120.A O no hydrogen 3.539 N/A SER 124.A OG GLU 121.A O no hydrogen 2.982 N/A TYR 125.A N GLU 121.A O no hydrogen 3.144 N/A ILE 126.A N ALA 122.A O no hydrogen 2.870 N/A HIS 127.A N LEU 123.A O no hydrogen 2.770 N/A HIS 127.A NE2 ASP 182.A OD1 no hydrogen 2.857 N/A SER 128.A N SER 124.A O no hydrogen 2.921 N/A SER 128.A OG TYR 125.A O no hydrogen 2.623 N/A GLN 129.A N ILE 126.A O no hydrogen 2.962 N/A GLN 129.A NE2 SER 128.A OG no hydrogen 3.081 N/A GLY 130.A N HIS 127.A O no hydrogen 2.863 N/A ILE 131.A N ILE 126.A O no hydrogen 3.405 N/A HIS 133.A N ASP 182.A OD1 no hydrogen 2.743 N/A HIS 133.A NE2 GLY 152.A O no hydrogen 2.843 N/A ARG 134.A N ASP 182.A OD2 no hydrogen 2.921 N/A ARG 134.A NH1 GLU 52.A OE2 no hydrogen 2.914 N/A ARG 134.A NH1 GLY 155.A O no hydrogen 2.940 N/A ARG 134.A NH2 GLU 52.A OE1 no hydrogen 2.942 N/A ASP 135.A N HIS 133.A ND1 no hydrogen 2.977 N/A ASN 140.A N LYS 137.A O no hydrogen 2.883 N/A ILE 141.A N PRO 138.A O no hydrogen 3.313 N/A PHE 142.A N LYS 150.A O no hydrogen 2.835 N/A ILE 143.A N GLY 94.A O no hydrogen 2.971 N/A ASP 144.A N ASN 148.A O no hydrogen 2.889 N/A SER 146.A N ASP 144.A OD2 no hydrogen 2.843 N/A ARG 147.A N ASP 144.A O no hydrogen 2.917 N/A ARG 147.A NE GLU 111.A OE1 no hydrogen 2.930 N/A ARG 147.A NH1 GLU 103.A OE1 no hydrogen 3.433 N/A ARG 147.A NH1 GLU 103.A OE2 no hydrogen 2.876 N/A ARG 147.A NH2 GLU 103.A OE1 no hydrogen 3.027 N/A ARG 147.A NH2 GLU 111.A OE1 no hydrogen 2.989 N/A ASN 148.A N ASP 144.A OD2 no hydrogen 2.878 N/A VAL 149.A N GLN 118.A OE1 no hydrogen 2.916 N/A LYS 150.A N PHE 142.A O no hydrogen 2.884 N/A LYS 150.A NZ GLN 62.A O no hydrogen 2.768 N/A ILE 151.A N TYR 63.A O no hydrogen 2.948 N/A GLY 152.A N ASN 140.A O no hydrogen 2.952 N/A PHE 154.A N TYR 67.A OH no hydrogen 3.081 N/A GLY 155.A N HIS 133.A O no hydrogen 2.801 N/A ARG 162.A N ASN 159.A O no hydrogen 3.308 N/A TYR 165.A OH GLU 192.A OE1 no hydrogen 2.406 N/A TYR 165.A OH GLU 192.A OE2 no hydrogen 3.138 N/A VAL 166.A N ALA 163.A O no hydrogen 3.474 N/A THR 168.A OG1 HIS 239.A O no hydrogen 3.516 N/A GLU 169.A N GLU 169.A OE1 no hydrogen 2.748 N/A VAL 170.A N ALA 167.A O no hydrogen 3.087 N/A HIS 176.A N THR 174.A OG1 no hydrogen 3.232 N/A TYR 177.A OH LYS 158.A O no hydrogen 2.718 N/A GLU 179.A N GLU 179.A OE2 no hydrogen 2.639 N/A LYS 180.A N ASN 178.A OD1 no hydrogen 3.108 N/A LYS 180.A NZ PRO 241.A O no hydrogen 3.094 N/A LYS 180.A NZ ARG 244.A O no hydrogen 2.643 N/A ILE 181.A N ASN 178.A O no hydrogen 3.141 N/A ASP 182.A N GLU 179.A O no hydrogen 3.049 N/A TYR 184.A N LYS 180.A O no hydrogen 3.082 N/A SER 185.A N ILE 181.A O no hydrogen 3.148 N/A SER 185.A OG TYR 165.A O no hydrogen 2.780 N/A SER 185.A OG ILE 181.A O no hydrogen 3.078 N/A LEU 186.A N ASP 182.A O no hydrogen 2.926 N/A GLY 187.A N MET 183.A O no hydrogen 3.074 N/A ILE 188.A N TYR 184.A O no hydrogen 3.286 N/A ILE 189.A N SER 185.A O no hydrogen 2.987 N/A PHE 190.A N LEU 186.A O no hydrogen 2.828 N/A PHE 191.A N GLY 187.A O no hydrogen 3.036 N/A GLU 192.A N ILE 188.A O no hydrogen 3.033 N/A MET 193.A N ILE 189.A O no hydrogen 2.940 N/A MET 193.A N PHE 190.A O no hydrogen 2.980 N/A ILE 194.A N PHE 190.A O no hydrogen 3.120 N/A ILE 194.A N PHE 191.A O no hydrogen 3.203 N/A TYR 195.A N PHE 191.A O no hydrogen 2.895 N/A TYR 195.A OH ASP 220.A OD1 no hydrogen 3.392 N/A TYR 195.A OH ASP 220.A OD2 no hydrogen 2.753 N/A SER 198.A N GLU 202.A OE2 no hydrogen 3.074 N/A SER 198.A OG GLU 202.A OE1 no hydrogen 2.538 N/A GLU 202.A N THR 199.A OG1 no hydrogen 3.011 N/A ARG 203.A N THR 199.A O no hydrogen 3.050 N/A ARG 203.A NE GLU 192.A OE2 no hydrogen 2.631 N/A ARG 203.A NH2 TYR 165.A OH no hydrogen 2.973 N/A ARG 203.A NH2 GLU 192.A OE2 no hydrogen 3.353 N/A VAL 204.A N GLY 200.A O no hydrogen 3.173 N/A ASN 205.A N MET 201.A O no hydrogen 2.841 N/A ILE 206.A N GLU 202.A O no hydrogen 2.780 N/A LEU 207.A N ARG 203.A O no hydrogen 2.807 N/A LYS 208.A N VAL 204.A O no hydrogen 2.898 N/A LYS 209.A N ASN 205.A O no hydrogen 3.389 N/A LYS 209.A N ILE 206.A O no hydrogen 2.982 N/A LEU 210.A N ILE 206.A O no hydrogen 3.113 N/A ARG 211.A N LEU 207.A O no hydrogen 2.928 N/A ARG 211.A NH1 VAL 166.A O no hydrogen 2.836 N/A ARG 211.A NH2 VAL 166.A O no hydrogen 3.115 N/A SER 212.A N LYS 209.A O no hydrogen 3.014 N/A SER 212.A OG LYS 209.A O no hydrogen 2.621 N/A SER 212.A OG SER 214.A OG no hydrogen 3.105 N/A SER 214.A OG SER 212.A OG no hydrogen 3.105 N/A ILE 215.A N SER 212.A O no hydrogen 2.838 N/A GLU 216.A N LYS 209.A O no hydrogen 3.302 N/A PHE 221.A N PRO 218.A O no hydrogen 3.086 N/A LYS 225.A N ASP 222.A OD1 no hydrogen 2.433 N/A MET 226.A N ASP 222.A O no hydrogen 3.100 N/A GLU 229.A N GLU 229.A OE1 no hydrogen 2.602 N/A LYS 230.A N MET 226.A O no hydrogen 3.059 N/A LYS 230.A NZ ASP 223.A OD1 no hydrogen 2.797 N/A LYS 231.A N LYS 227.A O no hydrogen 3.079 N/A ILE 232.A N VAL 228.A O no hydrogen 2.864 N/A ILE 233.A N GLU 229.A O no hydrogen 2.930 N/A ARG 234.A N LYS 230.A O no hydrogen 2.920 N/A ARG 234.A NH2 ARG 234.A O no hydrogen 2.931 N/A ARG 234.A NH2 ASP 238.A OD2 no hydrogen 2.980 N/A LEU 235.A N LYS 231.A O no hydrogen 3.146 N/A LEU 236.A N ILE 232.A O no hydrogen 2.915 N/A ILE 237.A N ILE 233.A O no hydrogen 2.840 N/A ASP 238.A N LEU 235.A O no hydrogen 3.395 N/A ASP 240.A N ASP 238.A OD1 no hydrogen 2.722 N/A ASN 242.A N ASP 240.A OD1 no hydrogen 2.924 N/A LYS 243.A N ASP 240.A O no hydrogen 2.969 N/A LYS 243.A NZ ASP 240.A OD2 no hydrogen 2.672 N/A ARG 244.A N PRO 241.A O no hydrogen 3.171 N/A ARG 244.A NH1 GLU 169.A OE1 no hydrogen 3.172 N/A ARG 244.A NH1 ASP 238.A O no hydrogen 2.624 N/A ARG 244.A NH2 GLU 169.A OE1 no hydrogen 3.148 N/A ARG 244.A NH2 GLU 169.A OE2 no hydrogen 2.578 N/A ARG 244.A NH2 LYS 180.A O no hydrogen 3.120 N/A LEU 250.A N GLY 246.A O no hydrogen 3.145 N/A LEU 251.A N ALA 247.A O no hydrogen 2.881 N/A ASN 252.A N ARG 248.A O no hydrogen 2.975 N/A SER 253.A N LEU 250.A O no hydrogen 3.254 N/A SER 253.A OG LEU 250.A O no hydrogen 2.780 N/A TRP 255.A N SER 253.A OG no hydrogen 2.974 N/A LYS 259.A NZ GLU 267.A OE1 no hydrogen 2.713 N/A LYS 259.A NZ GLU 267.A OE2 no hydrogen 2.942 N/A HIS 260.A ND1 ASP 110.A OD2 no hydrogen 2.761 N/A VAL 264.A N HIS 260.A O no hydrogen 3.024 N/A ILE 265.A N GLN 261.A O no hydrogen 2.703 N/A LYS 266.A N ASP 262.A O no hydrogen 2.985 N/A GLU 267.A N GLU 263.A O no hydrogen 2.982 N/A ALA 268.A N VAL 264.A O no hydrogen 3.157 N/A ALA 268.A N ILE 265.A O no hydrogen 3.098 N/A LEU 269.A N ILE 265.A O no hydrogen 2.886 N/A LYS 270.A N LYS 266.A O no hydrogen 3.212 N/A SER 271.A N GLU 267.A O no hydrogen 3.287 N/A SER 271.A OG GLU 267.A O no hydrogen 3.233 N/A SER 271.A OG ALA 268.A O no hydrogen 2.759 N/A