Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2a4a_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 4.A N ASN 1.A OD1 no hydrogen 3.337 N/A LYS 5.A N ASN 1.A O no hydrogen 3.156 N/A PHE 6.A N TYR 2.A O no hydrogen 2.802 N/A ALA 7.A N THR 3.A O no hydrogen 2.980 N/A ALA 8.A N GLU 4.A O no hydrogen 2.802 N/A TRP 9.A N LYS 5.A O no hydrogen 3.012 N/A SER 10.A N PHE 6.A O no hydrogen 3.011 N/A SER 10.A OG PHE 6.A O no hydrogen 3.093 N/A VAL 11.A N ALA 7.A O no hydrogen 2.917 N/A ILE 12.A N ALA 8.A O no hydrogen 3.119 N/A CYS 13.A N TRP 9.A O no hydrogen 3.353 N/A CYS 13.A SG TRP 9.A O no hydrogen 3.371 N/A LEU 14.A N VAL 11.A O no hydrogen 2.960 N/A THR 15.A N ILE 12.A O no hydrogen 2.940 N/A THR 15.A OG1 VAL 11.A O no hydrogen 2.741 N/A ASP 16.A N ILE 236.A O no hydrogen 2.708 N/A HIS 17.A N ALA 45.A O no hydrogen 2.780 N/A HIS 17.A NE2 GLU 35.A OE1 no hydrogen 2.850 N/A THR 18.A N SER 238.A O no hydrogen 3.037 N/A THR 18.A OG1 ASP 16.A O no hydrogen 2.753 N/A THR 18.A OG1 SER 238.A O no hydrogen 3.535 N/A PHE 19.A N CYS 47.A O no hydrogen 3.036 N/A GLU 22.A N GLU 22.A OE1 no hydrogen 2.777 N/A GLY 24.A N ASP 21.A O no hydrogen 3.017 N/A THR 25.A N ASP 28.A OD2 no hydrogen 2.893 N/A THR 25.A OG1 ASP 28.A OD2 no hydrogen 3.465 N/A ILE 29.A N THR 25.A O no hydrogen 3.173 N/A ARG 30.A N GLU 26.A O no hydrogen 2.713 N/A ARG 30.A NE GLU 63.A OE1 no hydrogen 2.798 N/A ARG 30.A NE GLU 63.A OE2 no hydrogen 3.196 N/A ARG 30.A NH2 GLU 63.A OE2 no hydrogen 2.622 N/A GLU 31.A N ASP 27.A O no hydrogen 3.065 N/A LEU 32.A N ASP 28.A O no hydrogen 2.953 N/A CYS 33.A N ILE 29.A O no hydrogen 2.918 N/A CYS 33.A SG ILE 29.A O no hydrogen 3.369 N/A ASN 34.A N ARG 30.A O no hydrogen 2.877 N/A GLU 35.A N GLU 31.A O no hydrogen 2.933 N/A SER 36.A N LEU 32.A O no hydrogen 2.988 N/A SER 36.A OG CYS 33.A O no hydrogen 2.710 N/A VAL 37.A N ASN 34.A O no hydrogen 3.255 N/A LYS 38.A N GLU 35.A O no hydrogen 3.517 N/A ALA 43.A N SER 36.A O no hydrogen 2.954 N/A ALA 44.A N THR 15.A O no hydrogen 2.913 N/A VAL 46.A N LYS 70.A O no hydrogen 2.835 N/A CYS 47.A N HIS 17.A O no hydrogen 2.867 N/A CYS 47.A SG ALA 72.A O no hydrogen 3.997 N/A VAL 48.A N ALA 72.A O no hydrogen 2.971 N/A TYR 49.A OH GLU 22.A OE2 no hydrogen 2.590 N/A PHE 52.A N TYR 49.A O no hydrogen 3.059 N/A VAL 53.A N PRO 50.A O no hydrogen 3.189 N/A LYS 54.A NZ GLU 58.A OE1 no hydrogen 2.708 N/A LYS 54.A NZ GLU 58.A OE2 no hydrogen 2.960 N/A ILE 56.A N PHE 52.A O no hydrogen 3.200 N/A ASN 57.A N VAL 53.A O no hydrogen 2.943 N/A GLU 58.A N LYS 54.A O no hydrogen 2.834 N/A ILE 60.A N PHE 55.A O no hydrogen 3.130 N/A LYS 61.A N ILE 56.A O no hydrogen 3.063 N/A LYS 61.A NZ ASN 57.A OD1 no hydrogen 3.094 N/A GLN 62.A N GLU 58.A O no hydrogen 3.135 N/A GLN 62.A N LYS 59.A O no hydrogen 3.088 N/A GLU 63.A N LYS 59.A O no hydrogen 3.030 N/A ILE 64.A N ILE 60.A O no hydrogen 2.668 N/A LYS 70.A N ALA 44.A O no hydrogen 3.040 N/A ILE 71.A N ASP 100.A OD2 no hydrogen 2.812 N/A ALA 72.A N VAL 46.A O no hydrogen 2.810 N/A CYS 73.A N GLU 101.A O no hydrogen 2.944 N/A CYS 73.A SG VAL 74.A O no hydrogen 3.511 N/A VAL 74.A N VAL 48.A O no hydrogen 3.006 N/A ILE 75.A N ASP 103.A O no hydrogen 2.889 N/A GLY 80.A N ASN 76.A O no hydrogen 2.904 N/A LYS 86.A N SER 83.A OG no hydrogen 3.155 N/A LYS 86.A NZ ASP 82.A OD2 no hydrogen 3.051 N/A LYS 86.A NZ ASP 90.A OD2 no hydrogen 2.725 N/A VAL 87.A N SER 83.A O no hydrogen 3.034 N/A LEU 88.A N MET 84.A O no hydrogen 2.849 N/A ASN 89.A N GLU 85.A O no hydrogen 2.920 N/A ASP 90.A N LYS 86.A O no hydrogen 2.782 N/A THR 91.A N VAL 87.A O no hydrogen 2.811 N/A THR 91.A OG1 VAL 87.A O no hydrogen 2.843 N/A GLU 92.A N LEU 88.A O no hydrogen 2.896 N/A LYS 93.A N ASN 89.A O no hydrogen 3.078 N/A LYS 93.A NZ ASP 97.A OD2 no hydrogen 2.902 N/A ALA 94.A N ASP 90.A O no hydrogen 2.916 N/A LEU 95.A N THR 91.A O no hydrogen 2.887 N/A ASP 96.A N GLU 92.A O no hydrogen 2.884 N/A ASP 97.A N LYS 93.A O no hydrogen 2.851 N/A GLY 98.A N LEU 95.A O no hydrogen 3.104 N/A ALA 99.A N ALA 94.A O no hydrogen 3.008 N/A ASP 100.A N ILE 71.A O no hydrogen 2.838 N/A GLU 101.A N ILE 71.A O no hydrogen 3.043 N/A ILE 102.A N ILE 137.A O no hydrogen 3.055 N/A ASP 103.A N CYS 73.A O no hydrogen 2.850 N/A LEU 104.A N LYS 139.A O no hydrogen 2.687 N/A VAL 105.A N ILE 75.A O no hydrogen 2.940 N/A ILE 106.A N ILE 141.A O no hydrogen 3.415 N/A ASN 107.A ND2 GLU 121.A OE2 no hydrogen 3.046 N/A TYR 108.A N ILE 106.A O no hydrogen 2.812 N/A LYS 110.A N ASN 107.A OD1 no hydrogen 3.259 N/A LYS 110.A NZ GLU 117.A OE1 no hydrogen 2.863 N/A ILE 111.A N ASN 107.A O no hydrogen 3.280 N/A ILE 112.A N TYR 108.A O no hydrogen 2.998 N/A GLU 113.A N LYS 109.A O no hydrogen 2.917 N/A ASN 114.A N LYS 110.A O no hydrogen 2.691 N/A THR 115.A OG1 ILE 111.A O no hydrogen 2.723 N/A GLY 118.A N ASN 114.A O no hydrogen 2.882 N/A LEU 119.A N THR 115.A O no hydrogen 2.782 N/A LYS 120.A N ASP 116.A O no hydrogen 3.154 N/A GLU 121.A N GLU 117.A O no hydrogen 2.980 N/A ALA 122.A N GLY 118.A O no hydrogen 2.953 N/A THR 123.A N LEU 119.A O no hydrogen 3.039 N/A THR 123.A OG1 LEU 119.A O no hydrogen 3.276 N/A THR 123.A OG1 ALA 159.A O no hydrogen 2.699 N/A LYS 124.A N LYS 120.A O no hydrogen 2.978 N/A LEU 125.A N GLU 121.A O no hydrogen 2.847 N/A THR 126.A N ALA 122.A O no hydrogen 3.056 N/A THR 126.A OG1 ALA 122.A O no hydrogen 2.853 N/A GLN 127.A N THR 123.A O no hydrogen 2.983 N/A GLN 127.A NE2 ASN 164.A OD1 no hydrogen 2.597 N/A SER 128.A N LYS 124.A O no hydrogen 3.005 N/A SER 128.A OG LYS 124.A O no hydrogen 3.496 N/A SER 128.A OG LEU 125.A O no hydrogen 2.801 N/A VAL 129.A N LEU 125.A O no hydrogen 2.982 N/A LYS 130.A N THR 126.A O no hydrogen 2.871 N/A LYS 130.A NZ LEU 133.A O no hydrogen 3.305 N/A LYS 131.A N GLN 127.A O no hydrogen 3.143 N/A LEU 132.A N VAL 129.A O no hydrogen 2.994 N/A LEU 133.A N LYS 130.A O no hydrogen 2.795 N/A LYS 136.A N LEU 133.A O no hydrogen 3.176 N/A LEU 138.A N ASP 166.A OD2 no hydrogen 2.921 N/A LYS 139.A N ILE 102.A O no hydrogen 2.783 N/A LYS 139.A NZ ASP 16.A OD2 no hydrogen 2.853 N/A LYS 139.A NZ GLU 101.A OE1 no hydrogen 2.783 N/A LYS 139.A NZ ASP 103.A OD1 no hydrogen 2.772 N/A LYS 139.A NZ ASP 103.A OD2 no hydrogen 3.506 N/A VAL 140.A N PHE 167.A O no hydrogen 2.930 N/A ILE 141.A N LEU 104.A O no hydrogen 2.688 N/A ILE 142.A N LYS 169.A O no hydrogen 3.118 N/A VAL 144.A N THR 170.A O no hydrogen 3.011 N/A GLU 146.A N GLU 143.A O no hydrogen 3.002 N/A LEU 147.A N GLU 143.A O no hydrogen 3.005 N/A LYS 148.A N VAL 144.A O no hydrogen 2.826 N/A THR 149.A N LEU 147.A O no hydrogen 2.811 N/A LEU 152.A N THR 149.A OG1 no hydrogen 3.044 N/A ILE 153.A N THR 149.A O no hydrogen 2.973 N/A ILE 154.A N GLU 150.A O no hydrogen 2.996 N/A LYS 155.A N ASP 151.A O no hydrogen 2.992 N/A LYS 155.A NZ ASP 151.A OD1 no hydrogen 3.491 N/A LYS 155.A NZ ASP 151.A OD2 no hydrogen 2.729 N/A THR 156.A N LEU 152.A O no hydrogen 2.858 N/A THR 156.A OG1 LEU 152.A O no hydrogen 2.648 N/A THR 157.A N ILE 153.A O no hydrogen 2.961 N/A THR 157.A OG1 ILE 153.A O no hydrogen 2.863 N/A LEU 158.A N ILE 154.A O no hydrogen 2.920 N/A ALA 159.A N LYS 155.A O no hydrogen 2.905 N/A VAL 160.A N THR 156.A O no hydrogen 3.005 N/A LEU 161.A N THR 157.A O no hydrogen 3.040 N/A ASN 162.A N LEU 158.A O no hydrogen 2.955 N/A GLY 163.A N VAL 160.A O no hydrogen 2.991 N/A ASN 164.A N LEU 161.A O no hydrogen 2.918 N/A ALA 165.A N VAL 160.A O no hydrogen 3.247 N/A ASP 166.A N LEU 138.A O no hydrogen 2.920 N/A PHE 167.A N LEU 138.A O no hydrogen 3.090 N/A ILE 168.A N GLY 206.A O no hydrogen 3.033 N/A LYS 169.A N VAL 140.A O no hydrogen 2.818 N/A LYS 169.A NZ ASP 103.A OD2 no hydrogen 3.056 N/A THR 170.A N LYS 208.A O no hydrogen 3.012 N/A THR 170.A OG1 SER 171.A OG no hydrogen 3.134 N/A THR 170.A OG1 SER 210.A O no hydrogen 3.039 N/A THR 170.A OG1 SER 210.A OG no hydrogen 3.348 N/A SER 171.A N SER 210.A OG no hydrogen 3.176 N/A SER 171.A OG THR 170.A OG1 no hydrogen 3.134 N/A SER 171.A OG SER 210.A O no hydrogen 3.384 N/A THR 172.A N GLU 143.A OE1 no hydrogen 2.963 N/A THR 172.A OG1 GLU 143.A OE1 no hydrogen 3.497 N/A THR 172.A OG1 GLU 143.A OE2 no hydrogen 2.597 N/A LYS 174.A N THR 172.A OG1 no hydrogen 2.882 N/A LYS 174.A NZ LEU 20.A O no hydrogen 2.726 N/A THR 180.A N SER 183.A OG no hydrogen 3.314 N/A THR 180.A OG1 SER 183.A OG no hydrogen 3.352 N/A SER 183.A N THR 180.A OG1 no hydrogen 3.392 N/A SER 183.A OG THR 180.A O no hydrogen 3.286 N/A SER 183.A OG THR 180.A OG1 no hydrogen 3.352 N/A VAL 184.A N THR 180.A O no hydrogen 3.080 N/A GLU 185.A N PRO 181.A O no hydrogen 2.883 N/A TYR 186.A N SER 182.A O no hydrogen 2.977 N/A ILE 187.A N SER 183.A O no hydrogen 3.017 N/A ILE 188.A N VAL 184.A O no hydrogen 2.953 N/A LYS 189.A N GLU 185.A O no hydrogen 2.909 N/A LYS 189.A NZ GLU 150.A OE2 no hydrogen 2.574 N/A ALA 190.A N TYR 186.A O no hydrogen 3.005 N/A ILE 191.A N ILE 187.A O no hydrogen 2.898 N/A LYS 192.A N ILE 188.A O no hydrogen 2.930 N/A GLU 193.A N LYS 189.A O no hydrogen 3.113 N/A TYR 194.A N ALA 190.A O no hydrogen 2.907 N/A ILE 195.A N ILE 191.A O no hydrogen 2.836 N/A LYS 196.A N LYS 192.A O no hydrogen 2.912 N/A ASN 197.A N GLU 193.A O no hydrogen 3.107 N/A ASN 198.A N ILE 195.A O no hydrogen 2.933 N/A ASN 198.A ND2 TYR 194.A O no hydrogen 2.819 N/A GLU 200.A N GLU 200.A OE1 no hydrogen 2.788 N/A LYS 201.A N ASN 198.A O no hydrogen 2.946 N/A ASN 202.A N PRO 199.A O no hydrogen 3.138 N/A LYS 204.A N LYS 201.A O no hydrogen 2.927 N/A GLY 206.A N ASP 166.A O no hydrogen 2.827 N/A LEU 207.A N ASN 233.A O no hydrogen 2.965 N/A LYS 208.A N ILE 168.A O no hydrogen 2.806 N/A LYS 208.A NZ ASP 16.A OD2 no hydrogen 2.694 N/A LYS 208.A NZ ASP 103.A OD2 no hydrogen 2.904 N/A VAL 209.A N ARG 235.A O no hydrogen 2.935 N/A SER 210.A N THR 170.A OG1 no hydrogen 2.991 N/A SER 210.A OG THR 170.A OG1 no hydrogen 3.348 N/A SER 210.A OG SER 171.A O no hydrogen 2.624 N/A THR 218.A N ASP 215.A OD2 no hydrogen 2.791 N/A THR 218.A OG1 ASP 215.A OD1 no hydrogen 3.224 N/A THR 218.A OG1 ASP 215.A OD2 no hydrogen 2.948 N/A ALA 219.A N ASP 215.A O no hydrogen 3.079 N/A SER 220.A N LEU 216.A O no hydrogen 2.881 N/A SER 220.A OG LEU 216.A O no hydrogen 2.847 N/A HIS 221.A N ASN 217.A O no hydrogen 3.021 N/A TYR 222.A N THR 218.A O no hydrogen 3.275 N/A ILE 223.A N ALA 219.A O no hydrogen 3.108 N/A LEU 224.A N SER 220.A O no hydrogen 2.954 N/A LEU 225.A N HIS 221.A O no hydrogen 3.013 N/A ALA 226.A N TYR 222.A O no hydrogen 3.031 N/A ARG 227.A N ILE 223.A O no hydrogen 2.889 N/A ARG 228.A N LEU 224.A O no hydrogen 2.813 N/A PHE 229.A N LEU 225.A O no hydrogen 3.047 N/A LEU 230.A N ALA 226.A O no hydrogen 2.914 N/A SER 231.A N ALA 226.A O no hydrogen 2.965 N/A SER 231.A OG ARG 227.A O no hydrogen 3.014 N/A ASN 233.A ND2 ASN 203.A O no hydrogen 2.897 N/A ARG 235.A N LEU 207.A O no hydrogen 2.988 N/A ARG 235.A NH1 ASP 16.A OD1 no hydrogen 2.900 N/A ARG 235.A NH1 ASP 16.A OD2 no hydrogen 3.480 N/A ARG 235.A NH1 GLU 101.A OE1 no hydrogen 2.925 N/A ARG 235.A NH1 GLU 101.A OE2 no hydrogen 3.459 N/A ARG 235.A NH2 GLU 101.A OE2 no hydrogen 2.854 N/A ILE 236.A N LEU 14.A O no hydrogen 2.979 N/A GLY 237.A N VAL 209.A O no hydrogen 2.930 N/A SER 238.A N ASP 16.A O no hydrogen 3.444 N/A SER 238.A OG ILE 213.A O no hydrogen 2.650 N/A SER 240.A N SER 238.A OG no hydrogen 3.180 N/A LEU 241.A N SER 238.A OG no hydrogen 2.975 N/A LYS 244.A N SER 240.A O no hydrogen 3.274 N/A LEU 245.A N LEU 241.A O no hydrogen 2.842 N/A ARG 246.A N VAL 242.A O no hydrogen 2.922 N/A ARG 246.A NE GLU 35.A O no hydrogen 2.969 N/A ARG 246.A NH1 PRO 41.A O no hydrogen 2.765 N/A ARG 246.A NH2 GLU 35.A O no hydrogen 3.018 N/A ARG 246.A NH2 PRO 41.A O no hydrogen 2.792 N/A VAL 248.A N LYS 244.A O no hydrogen 3.164 N/A ILE 249.A N LEU 245.A O no hydrogen 3.005 N/A SER 250.A N ARG 246.A O no hydrogen 2.974 N/A