Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2c2r_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 3.A N SER 145.A O no hydrogen 2.712 N/A LEU 4.A N LEU 109.A O no hydrogen 2.625 N/A PHE 5.A N GLY 143.A O no hydrogen 2.554 N/A VAL 6.A N ALA 107.A O no hydrogen 2.919 N/A ASP 7.A N THR 141.A O no hydrogen 2.925 N/A PHE 8.A N ASP 105.A O no hydrogen 3.071 N/A ASP 9.A N THR 139.A O no hydrogen 3.011 N/A TYR 10.A OH GLU 17.A OE1 no hydrogen 2.387 N/A GLN 14.A N TYR 10.A O no hydrogen 2.742 N/A GLN 14.A NE2 ASP 9.A O no hydrogen 2.611 N/A GLN 14.A NE2 THR 139.A O no hydrogen 3.364 N/A VAL 15.A N PHE 11.A O no hydrogen 2.747 N/A GLU 16.A N TYR 12.A O no hydrogen 3.312 N/A GLU 17.A N ALA 13.A O no hydrogen 3.031 N/A VAL 18.A N GLN 14.A O no hydrogen 2.933 N/A VAL 18.A N VAL 15.A O no hydrogen 3.013 N/A LEU 19.A N VAL 15.A O no hydrogen 2.980 N/A ASN 20.A N GLU 16.A O no hydrogen 2.907 N/A SER 22.A N ASN 20.A OD1 no hydrogen 2.950 N/A SER 22.A OG ASN 20.A OD1 no hydrogen 2.647 N/A LEU 23.A N ASN 20.A O no hydrogen 3.246 N/A LYS 26.A N LEU 23.A O no hydrogen 2.455 N/A VAL 28.A N ASN 47.A OD1 no hydrogen 2.962 N/A VAL 29.A N VAL 72.A O no hydrogen 3.024 N/A VAL 30.A N THR 45.A O no hydrogen 2.953 N/A CYS 31.A N LEU 74.A O no hydrogen 2.609 N/A CYS 31.A SG VAL 29.A O no hydrogen 3.456 N/A VAL 32.A N ALA 42.A O no hydrogen 2.931 N/A SER 34.A N SER 40.A O no hydrogen 2.699 N/A SER 34.A OG SER 40.A O no hydrogen 3.325 N/A SER 34.A OG SER 40.A OG no hydrogen 2.914 N/A ARG 36.A N SER 34.A OG no hydrogen 3.421 N/A ARG 36.A NE LYS 252.A O no hydrogen 3.295 N/A ARG 36.A NH2 MET 251.A O no hydrogen 2.993 N/A PHE 37.A N SER 40.A OG no hydrogen 3.149 N/A SER 40.A OG SER 34.A OG no hydrogen 2.914 N/A SER 40.A OG PHE 37.A O no hydrogen 2.416 N/A ALA 42.A N VAL 32.A O no hydrogen 3.043 N/A VAL 43.A N ILE 59.A O no hydrogen 2.891 N/A ALA 44.A N VAL 30.A O no hydrogen 2.769 N/A THR 45.A N VAL 30.A O no hydrogen 3.310 N/A ASN 47.A N VAL 28.A O no hydrogen 3.053 N/A ASN 47.A ND2 GLU 17.A OE2 no hydrogen 2.897 N/A ASN 47.A ND2 LYS 26.A O no hydrogen 3.006 N/A ALA 50.A N ASN 47.A O no hydrogen 3.107 N/A ALA 50.A N ASN 47.A OD1 no hydrogen 3.388 N/A ARG 51.A N ASN 47.A O no hydrogen 2.897 N/A LYS 52.A N TYR 48.A O no hydrogen 3.194 N/A PHE 53.A N ALA 50.A O no hydrogen 2.919 N/A GLY 54.A N ARG 51.A O no hydrogen 2.934 N/A VAL 55.A N ALA 50.A O no hydrogen 3.398 N/A GLY 58.A N VAL 43.A O no hydrogen 2.711 N/A ILE 61.A N GLY 41.A O no hydrogen 3.263 N/A ALA 64.A N PRO 60.A O no hydrogen 3.202 N/A LYS 65.A N ILE 61.A O no hydrogen 3.123 N/A LYS 65.A N VAL 62.A O no hydrogen 2.944 N/A LYS 65.A NZ ASP 39.A OD1 no hydrogen 2.848 N/A LYS 66.A N VAL 62.A O no hydrogen 3.155 N/A LEU 68.A N ALA 64.A O no hydrogen 3.151 N/A ALA 71.A N LEU 68.A O no hydrogen 3.150 N/A VAL 72.A N PRO 27.A O no hydrogen 2.993 N/A TYR 73.A OH ALA 64.A O no hydrogen 2.764 N/A TYR 73.A OH LEU 68.A O no hydrogen 2.591 N/A LEU 74.A N VAL 29.A O no hydrogen 2.947 N/A ARG 77.A N TYR 81.A OH no hydrogen 3.387 N/A ARG 77.A NE GLU 16.A OE2 no hydrogen 3.149 N/A ARG 77.A NH2 GLU 16.A OE2 no hydrogen 3.281 N/A TYR 81.A N ARG 77.A O no hydrogen 3.307 N/A TYR 81.A OH GLU 16.A OE2 no hydrogen 2.873 N/A GLN 82.A N LYS 78.A O no hydrogen 2.675 N/A GLN 83.A N GLU 79.A O no hydrogen 3.015 N/A VAL 84.A N VAL 80.A O no hydrogen 3.050 N/A SER 85.A N TYR 81.A O no hydrogen 2.781 N/A SER 85.A OG ILE 104.A O no hydrogen 2.545 N/A SER 86.A N GLN 82.A O no hydrogen 2.816 N/A SER 86.A OG GLN 82.A O no hydrogen 3.025 N/A ARG 87.A N GLN 83.A O no hydrogen 3.041 N/A ARG 87.A NE GLU 136.A OE2 no hydrogen 2.498 N/A ILE 88.A N VAL 84.A O no hydrogen 3.110 N/A MET 89.A N SER 85.A O no hydrogen 2.723 N/A ASN 90.A N SER 86.A O no hydrogen 2.798 N/A LEU 91.A N ARG 87.A O no hydrogen 2.928 N/A LEU 92.A N ILE 88.A O no hydrogen 2.965 N/A ARG 93.A N MET 89.A O no hydrogen 2.504 N/A ARG 93.A NE ASN 90.A OD1 no hydrogen 2.525 N/A ARG 93.A NH1 GLU 97.A OE2 no hydrogen 3.118 N/A GLU 94.A N LEU 91.A O no hydrogen 3.347 N/A SER 96.A OG ASP 110.A O no hydrogen 2.656 N/A LYS 98.A NZ SER 96.A OG no hydrogen 2.718 N/A LYS 98.A NZ ASP 110.A O no hydrogen 2.975 N/A LYS 98.A NZ ASP 110.A OD1 no hydrogen 2.954 N/A GLU 100.A N TYR 108.A O no hydrogen 2.748 N/A SER 103.A N GLU 106.A O no hydrogen 3.370 N/A ASP 105.A N SER 103.A OG no hydrogen 3.036 N/A GLU 106.A N SER 103.A O no hydrogen 3.249 N/A ALA 107.A N VAL 6.A O no hydrogen 3.155 N/A TYR 108.A N GLU 100.A O no hydrogen 2.754 N/A LEU 109.A N LEU 4.A O no hydrogen 2.548 N/A ASP 110.A N LYS 98.A O no hydrogen 3.377 N/A ILE 111.A N ILE 2.A O no hydrogen 3.007 N/A SER 112.A N ASP 110.A OD1 no hydrogen 3.252 N/A SER 112.A OG ASP 110.A OD1 no hydrogen 2.888 N/A SER 112.A OG ASP 110.A OD2 no hydrogen 2.842 N/A LYS 114.A NZ SER 96.A OG no hydrogen 3.105 N/A VAL 115.A N ILE 111.A O no hydrogen 3.123 N/A ARG 119.A N ASP 117.A OD2 no hydrogen 3.254 N/A ALA 121.A N ASP 117.A O no hydrogen 3.242 N/A ASN 123.A N ARG 119.A O no hydrogen 3.094 N/A LEU 124.A N ALA 121.A O no hydrogen 3.046 N/A GLY 125.A N TYR 122.A O no hydrogen 2.468 N/A ILE 128.A N GLY 125.A O no hydrogen 2.943 N/A LYS 129.A N GLY 125.A O no hydrogen 2.420 N/A LYS 129.A NZ ASN 161.A O no hydrogen 3.421 N/A LYS 129.A NZ ASN 161.A OD1 no hydrogen 2.973 N/A ASN 130.A N LEU 126.A O no hydrogen 2.664 N/A ILE 132.A N ILE 128.A O no hydrogen 3.122 N/A GLU 134.A N ASN 130.A O no hydrogen 2.870 N/A LYS 135.A N LYS 131.A O no hydrogen 2.657 N/A GLU 136.A N ILE 132.A O no hydrogen 3.041 N/A THR 139.A N GLN 14.A OE1 no hydrogen 2.423 N/A THR 139.A OG1 ASP 9.A OD2 no hydrogen 3.391 N/A THR 139.A OG1 GLN 14.A OE1 no hydrogen 2.633 N/A THR 141.A N ASP 7.A O no hydrogen 2.957 N/A THR 141.A OG1 ASP 9.A OD1 no hydrogen 2.755 N/A THR 141.A OG1 ASP 9.A OD2 no hydrogen 3.460 N/A VAL 142.A N GLY 162.A O no hydrogen 3.253 N/A GLY 143.A N PHE 5.A O no hydrogen 2.734 N/A SER 145.A N VAL 3.A O no hydrogen 2.981 N/A SER 145.A OG ILE 166.A O no hydrogen 2.525 N/A LYS 146.A N SER 145.A OG no hydrogen 2.543 N/A LYS 146.A NZ ASP 231.A O no hydrogen 2.809 N/A LYS 146.A NZ ASP 231.A OD1 no hydrogen 3.532 N/A LYS 146.A NZ ASP 231.A OD2 no hydrogen 3.307 N/A LYS 148.A NZ GLU 100.A OE1 no hydrogen 2.915 N/A LYS 148.A NZ GLU 100.A OE2 no hydrogen 2.684 N/A LYS 148.A NZ GLU 235.A OE2 no hydrogen 3.499 N/A PHE 150.A N ASN 147.A O no hydrogen 3.065 N/A PHE 150.A N ASN 147.A OD1 no hydrogen 3.145 N/A ALA 151.A N ASN 147.A O no hydrogen 3.145 N/A LYS 152.A N LYS 148.A O no hydrogen 3.019 N/A LYS 152.A NZ GLU 106.A OE1 no hydrogen 2.641 N/A LYS 152.A NZ GLU 106.A OE2 no hydrogen 2.723 N/A ILE 153.A N VAL 149.A O no hydrogen 3.174 N/A ALA 154.A N PHE 150.A O no hydrogen 2.823 N/A ALA 155.A N ALA 151.A O no hydrogen 3.133 N/A ASP 156.A N LYS 152.A O no hydrogen 3.211 N/A MET 157.A N ILE 153.A O no hydrogen 3.201 N/A MET 157.A N ALA 154.A O no hydrogen 3.166 N/A ALA 158.A N ALA 154.A O no hydrogen 3.157 N/A ALA 158.A N ALA 155.A O no hydrogen 2.800 N/A LYS 159.A N ALA 155.A O no hydrogen 3.003 N/A ASN 161.A N ASP 9.A OD2 no hydrogen 2.707 N/A LYS 164.A N VAL 142.A O no hydrogen 3.323 N/A LYS 164.A NZ GLU 170.A OE2 no hydrogen 3.178 N/A ILE 166.A N ILE 144.A O no hydrogen 2.887 N/A GLU 169.A N ASP 167.A OD1 no hydrogen 2.615 N/A GLU 170.A N ASP 167.A OD1 no hydrogen 2.855 N/A VAL 171.A N ASP 167.A O no hydrogen 3.296 N/A ARG 173.A N GLU 169.A O no hydrogen 3.107 N/A ARG 173.A NH1 GLU 169.A OE1 no hydrogen 2.398 N/A LEU 174.A N GLU 170.A O no hydrogen 2.809 N/A ILE 175.A N VAL 171.A O no hydrogen 3.054 N/A GLU 177.A N LEU 174.A O no hydrogen 2.593 N/A LEU 178.A N LEU 174.A O no hydrogen 2.459 N/A ILE 180.A N ASN 200.A O no hydrogen 2.789 N/A ALA 181.A N ASP 179.A OD1 no hydrogen 2.827 N/A ASP 182.A N ASP 179.A O no hydrogen 2.516 N/A VAL 183.A N ILE 180.A O no hydrogen 3.000 N/A ILE 186.A N VAL 183.A O no hydrogen 2.869 N/A ALA 191.A N GLY 187.A O no hydrogen 2.893 N/A GLU 192.A N ASN 188.A O no hydrogen 2.964 N/A LYS 193.A N ILE 189.A O no hydrogen 3.146 N/A LYS 193.A NZ MET 216.A O no hydrogen 3.348 N/A LEU 194.A N THR 190.A O no hydrogen 3.293 N/A LEU 194.A N ALA 191.A O no hydrogen 2.750 N/A LYS 195.A N ALA 191.A O no hydrogen 3.238 N/A LYS 195.A N GLU 192.A O no hydrogen 2.643 N/A LYS 196.A N GLU 192.A O no hydrogen 3.472 N/A LEU 197.A N LYS 193.A O no hydrogen 3.480 N/A GLY 198.A N LYS 195.A O no hydrogen 2.991 N/A ILE 199.A N LEU 194.A O no hydrogen 2.555 N/A ASN 200.A N ASP 204.A OD2 no hydrogen 3.018 N/A LYS 201.A N ASP 204.A OD2 no hydrogen 2.629 N/A LYS 201.A NZ GLU 177.A O no hydrogen 2.412 N/A THR 205.A OG1 LEU 202.A O no hydrogen 2.537 N/A LEU 206.A N VAL 203.A O no hydrogen 2.789 N/A SER 207.A N ASP 204.A O no hydrogen 2.845 N/A LEU 213.A N GLU 209.A O no hydrogen 3.398 N/A LYS 214.A N PHE 210.A O no hydrogen 2.918 N/A GLY 215.A N LYS 212.A O no hydrogen 2.966 N/A MET 216.A N LEU 213.A O no hydrogen 2.649 N/A ILE 217.A N LEU 213.A O no hydrogen 2.993 N/A ALA 222.A N GLY 218.A O no hydrogen 2.809 N/A LYS 223.A N GLU 219.A O no hydrogen 2.537 N/A TYR 224.A N ALA 220.A O no hydrogen 2.814 N/A TYR 224.A OH PRO 184.A O no hydrogen 2.791 N/A LEU 225.A N LYS 221.A O no hydrogen 3.396 N/A ILE 226.A N ALA 222.A O no hydrogen 3.223 N/A SER 227.A N LYS 223.A O no hydrogen 2.844 N/A SER 227.A OG GLU 232.A O no hydrogen 2.880 N/A LEU 228.A N TYR 224.A O no hydrogen 3.086 N/A ALA 229.A N LEU 225.A O no hydrogen 2.931 N/A ARG 230.A N ILE 226.A O no hydrogen 3.183 N/A ASP 231.A N LEU 228.A O no hydrogen 2.680 N/A GLU 232.A N SER 227.A O no hydrogen 3.069 N/A ARG 238.A N GLU 100.A OE2 no hydrogen 3.148 N/A ARG 242.A NH1 GLN 82.A OE1 no hydrogen 3.546 N/A LYS 243.A NZ VAL 241.A O no hydrogen 3.365 N/A ILE 245.A N PHE 337.A O no hydrogen 3.190 N/A ARG 247.A N VAL 335.A O no hydrogen 3.043 N/A ARG 247.A NE GLU 271.A OE1 no hydrogen 2.596 N/A VAL 249.A N ILE 333.A O no hydrogen 2.891 N/A MET 251.A N ARG 331.A O no hydrogen 2.981 N/A SER 255.A N ILE 330.A O no hydrogen 3.053 N/A ARG 256.A NE GLU 327.A O no hydrogen 2.572 N/A ARG 256.A NH1 LEU 323.A O no hydrogen 3.168 N/A ARG 256.A NH2 LEU 323.A O no hydrogen 2.531 N/A GLU 260.A N ASN 257.A O no hydrogen 2.814 N/A GLU 260.A N ASN 257.A OD1 no hydrogen 2.718 N/A ILE 261.A N ASN 257.A O no hydrogen 3.135 N/A LYS 262.A N LEU 258.A O no hydrogen 3.101 N/A LYS 262.A NZ GLU 259.A OE2 no hydrogen 2.959 N/A TYR 264.A N ILE 261.A O no hydrogen 2.690 N/A LEU 265.A N ILE 261.A O no hydrogen 3.243 N/A PHE 266.A N LYS 262.A O no hydrogen 2.548 N/A ARG 267.A N PRO 263.A O no hydrogen 2.871 N/A ARG 267.A N TYR 264.A O no hydrogen 2.688 N/A ALA 268.A N TYR 264.A O no hydrogen 2.717 N/A ILE 269.A N LEU 265.A O no hydrogen 3.080 N/A GLU 270.A N PHE 266.A O no hydrogen 3.264 N/A GLU 271.A N ARG 267.A O no hydrogen 2.959 N/A SER 272.A N ILE 269.A O no hydrogen 2.605 N/A SER 272.A OG ALA 268.A O no hydrogen 2.650 N/A TYR 273.A N ILE 269.A O no hydrogen 2.721 N/A TYR 273.A OH ILE 306.A O no hydrogen 2.432 N/A TYR 274.A N GLU 270.A O no hydrogen 3.339 N/A LYS 275.A NZ GLY 246.A O no hydrogen 2.688 N/A LEU 276.A N SER 272.A O no hydrogen 2.969 N/A LEU 276.A N TYR 273.A O no hydrogen 2.947 N/A ASP 277.A N TYR 273.A O no hydrogen 3.058 N/A ARG 279.A N ASP 277.A O no hydrogen 2.787 N/A ARG 279.A NE LEU 276.A O no hydrogen 3.197 N/A ARG 279.A NH2 LYS 275.A O no hydrogen 3.270 N/A ARG 279.A NH2 LEU 276.A O no hydrogen 3.310 N/A LYS 282.A N SER 338.A O no hydrogen 3.130 N/A LYS 282.A N LYS 339.A O no hydrogen 3.072 N/A ALA 283.A N SER 338.A O no hydrogen 3.041 N/A ILE 284.A N ARG 300.A O no hydrogen 2.996 N/A HIS 285.A N ARG 336.A O no hydrogen 2.630 N/A VAL 286.A N ARG 298.A O no hydrogen 3.019 N/A VAL 287.A N GLY 334.A O no hydrogen 2.780 N/A ALA 288.A N VAL 296.A O no hydrogen 2.977 N/A VAL 289.A N ARG 332.A O no hydrogen 2.683 N/A THR 290.A N ASP 294.A O no hydrogen 2.913 N/A THR 290.A OG1 ASP 292.A OD1 no hydrogen 2.361 N/A THR 290.A OG1 ASP 294.A O no hydrogen 3.134 N/A ASP 292.A N THR 290.A OG1 no hydrogen 3.398 N/A LEU 293.A N THR 290.A O no hydrogen 3.049 N/A ASP 294.A N THR 290.A OG1 no hydrogen 2.646 N/A VAL 296.A N ALA 288.A O no hydrogen 3.058 N/A ARG 298.A N VAL 286.A O no hydrogen 3.138 N/A ARG 298.A NE GLU 325.A OE2 no hydrogen 2.962 N/A ARG 298.A NH1 SER 297.A O no hydrogen 2.783 N/A ARG 298.A NH2 GLU 325.A OE2 no hydrogen 2.513 N/A ARG 300.A N ILE 284.A O no hydrogen 2.827 N/A ARG 300.A NH1 GLU 314.A OE2 no hydrogen 3.393 N/A PHE 302.A N LYS 282.A O no hydrogen 2.673 N/A HIS 304.A ND1 GLY 305.A O no hydrogen 2.863 N/A ILE 306.A N PRO 281.A O no hydrogen 2.597 N/A SER 307.A OG GLU 309.A OE1.A no hydrogen 3.445 N/A SER 307.A OG THR 310.A OG1 no hydrogen 2.717 N/A LYS 308.A NZ GLU 270.A OE2 no hydrogen 2.709 N/A THR 310.A N SER 307.A O no hydrogen 2.774 N/A THR 310.A N SER 307.A OG no hydrogen 3.086 N/A THR 310.A OG1 SER 307.A OG no hydrogen 2.717 N/A ALA 311.A N SER 307.A O no hydrogen 2.985 N/A TYR 312.A N LYS 308.A O no hydrogen 3.075 N/A TYR 312.A OH GLU 270.A OE1 no hydrogen 2.978 N/A SER 313.A N GLU 309.A O.A no hydrogen 3.386 N/A SER 313.A N GLU 309.A O.B no hydrogen 3.477 N/A GLU 314.A N THR 310.A O no hydrogen 2.719 N/A SER 315.A N ALA 311.A O no hydrogen 2.696 N/A SER 315.A OG ALA 311.A O no hydrogen 2.428 N/A LEU 318.A N GLU 314.A O no hydrogen 2.959 N/A LEU 319.A N SER 315.A O no hydrogen 3.136 N/A GLN 320.A N VAL 316.A O no hydrogen 2.743 N/A LYS 321.A N LYS 317.A O no hydrogen 2.732 N/A LYS 321.A NZ GLU 325.A OE1 no hydrogen 3.205 N/A ILE 322.A N LEU 318.A O no hydrogen 3.030 N/A LEU 323.A N LEU 319.A O no hydrogen 3.139 N/A GLU 324.A N LYS 321.A O no hydrogen 2.910 N/A GLU 325.A N LYS 321.A O no hydrogen 3.265 N/A ARG 328.A NE ASP 326.A OD1 no hydrogen 3.163 N/A ARG 328.A NE ASP 326.A OD2 no hydrogen 2.911 N/A ARG 328.A NH2 ASP 294.A OD2 no hydrogen 2.653 N/A ILE 330.A N SER 255.A O no hydrogen 2.642 N/A ARG 331.A N VAL 289.A O no hydrogen 2.916 N/A ARG 332.A N VAL 289.A O no hydrogen 3.421 N/A ILE 333.A N VAL 249.A O no hydrogen 2.851 N/A GLY 334.A N VAL 287.A O no hydrogen 2.777 N/A VAL 335.A N ARG 247.A O no hydrogen 3.018 N/A ARG 336.A N HIS 285.A O no hydrogen 2.703 N/A PHE 337.A N ILE 245.A O no hydrogen 3.030 N/A SER 338.A N ALA 283.A O no hydrogen 2.834 N/A LYS 339.A NZ THR 301.A OG1 no hydrogen 2.965 N/A ILE 341.A N ILE 280.A O no hydrogen 2.531 N/A