Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2c4n_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 1.A N GLU 195.A OE2 no hydrogen 2.902 N/A LYS 4.A N GLU 195.A O no hydrogen 2.796 N/A ASN 5.A N GLU 195.A O no hydrogen 3.094 N/A ASN 5.A ND2 GLU 195.A O no hydrogen 3.341 N/A VAL 6.A N PRO 37.A O no hydrogen 2.940 N/A ILE 7.A N VAL 197.A O no hydrogen 2.936 N/A CYS 8.A N VAL 39.A O no hydrogen 2.831 N/A CYS 8.A SG ASP 9.A O no hydrogen 3.454 N/A ASP 9.A N VAL 199.A O no hydrogen 2.811 N/A ILE 10.A N LEU 41.A O no hydrogen 2.980 N/A GLY 12.A N MET 15.A O no hydrogen 2.867 N/A VAL 13.A N ILE 10.A O no hydrogen 3.155 N/A LEU 14.A N ILE 10.A O no hydrogen 2.772 N/A MET 15.A N ILE 10.A O no hydrogen 3.124 N/A HIS 16.A N VAL 19.A O no hydrogen 2.664 N/A HIS 16.A NE2 SER 222.A O no hydrogen 2.773 N/A VAL 19.A N HIS 16.A O no hydrogen 2.894 N/A VAL 21.A N LEU 14.A O no hydrogen 2.838 N/A ALA 24.A N VAL 21.A O no hydrogen 2.928 N/A PHE 27.A N GLY 23.A O no hydrogen 2.889 N/A LEU 28.A N ALA 24.A O no hydrogen 2.948 N/A HIS 29.A N ALA 25.A O no hydrogen 2.897 N/A GLY 30.A N GLU 26.A O no hydrogen 2.956 N/A ILE 31.A N PHE 27.A O no hydrogen 3.281 N/A MET 32.A N LEU 28.A O no hydrogen 2.999 N/A ASP 33.A N HIS 29.A O no hydrogen 2.814 N/A LYS 34.A N GLY 30.A O no hydrogen 3.244 N/A LYS 34.A NZ ILE 250.A O no hydrogen 2.759 N/A LYS 34.A NZ ILE 250.A OXT no hydrogen 3.509 N/A GLY 35.A N MET 32.A O no hydrogen 2.886 N/A LEU 36.A N ILE 31.A O no hydrogen 3.302 N/A VAL 39.A N VAL 6.A O no hydrogen 2.978 N/A LEU 40.A N VAL 67.A O no hydrogen 2.830 N/A LEU 41.A N CYS 8.A O no hydrogen 2.953 N/A THR 42.A N TYR 69.A O no hydrogen 3.196 N/A ASN 43.A ND2 ASP 146.A OD2 no hydrogen 2.959 N/A ASN 43.A ND2 LYS 176.A O no hydrogen 2.990 N/A TYR 44.A N THR 42.A OG1 no hydrogen 3.295 N/A TYR 44.A OH HIS 148.A O no hydrogen 3.188 N/A THR 48.A N ASP 51.A OD2 no hydrogen 3.029 N/A GLN 50.A NE2 GLN 50.A O no hydrogen 3.402 N/A GLN 50.A NE2 ASN 54.A OD1 no hydrogen 3.161 N/A ASP 51.A N THR 48.A OG1 no hydrogen 3.011 N/A LEU 52.A N THR 48.A O no hydrogen 3.014 N/A ALA 53.A N GLY 49.A O no hydrogen 2.894 N/A ASN 54.A N GLN 50.A O no hydrogen 2.905 N/A ARG 55.A N ASP 51.A O no hydrogen 2.883 N/A ARG 55.A NE ASP 17.A O no hydrogen 3.129 N/A ARG 55.A NH1 GLN 47.A OE1 no hydrogen 3.278 N/A ARG 55.A NH2 ASP 11.A OD1 no hydrogen 2.776 N/A ARG 55.A NH2 ASP 17.A O no hydrogen 2.732 N/A PHE 56.A N LEU 52.A O no hydrogen 2.903 N/A ALA 57.A N ALA 53.A O no hydrogen 2.848 N/A THR 58.A N ASN 54.A O no hydrogen 2.850 N/A THR 58.A OG1 ASN 54.A O no hydrogen 2.796 N/A ALA 59.A N ARG 55.A O no hydrogen 3.197 N/A GLY 60.A N ALA 57.A O no hydrogen 2.904 N/A VAL 61.A N PHE 56.A O no hydrogen 2.761 N/A VAL 67.A N PRO 64.A O no hydrogen 3.397 N/A PHE 68.A N ASP 65.A O no hydrogen 3.309 N/A TYR 69.A N LEU 40.A O no hydrogen 2.905 N/A TYR 69.A OH ASP 77.A OD2 no hydrogen 2.580 N/A SER 71.A OG ASN 43.A O no hydrogen 2.580 N/A ALA 72.A N THR 70.A OG1 no hydrogen 3.126 N/A MET 73.A N THR 70.A OG1 no hydrogen 3.222 N/A ALA 74.A N THR 70.A O no hydrogen 2.956 N/A THR 75.A N SER 71.A O no hydrogen 2.971 N/A THR 75.A OG1 SER 71.A O no hydrogen 2.643 N/A ALA 76.A N ALA 72.A O no hydrogen 3.013 N/A ASP 77.A N MET 73.A O no hydrogen 2.891 N/A PHE 78.A N ALA 74.A O no hydrogen 2.862 N/A LEU 79.A N THR 75.A O no hydrogen 2.945 N/A ARG 80.A N ALA 76.A O no hydrogen 2.856 N/A GLN 82.A N LEU 79.A O no hydrogen 2.895 N/A GLN 82.A NE2 PHE 78.A O no hydrogen 2.994 N/A LYS 85.A NZ ALA 102.A O no hydrogen 2.617 N/A LYS 86.A N ASP 112.A OD2 no hydrogen 3.180 N/A ALA 87.A N THR 105.A O no hydrogen 2.982 N/A TYR 88.A N PHE 113.A O no hydrogen 2.830 N/A VAL 90.A N ILE 115.A O no hydrogen 2.761 N/A HIS 97.A N GLY 93.A O no hydrogen 3.188 N/A GLU 98.A N ALA 94.A O no hydrogen 2.974 N/A LEU 99.A N LEU 95.A O no hydrogen 2.967 N/A TYR 100.A N ILE 96.A O no hydrogen 3.074 N/A LYS 101.A N HIS 97.A O no hydrogen 3.019 N/A ALA 102.A N LEU 99.A O no hydrogen 2.979 N/A GLY 103.A N TYR 100.A O no hydrogen 3.046 N/A PHE 104.A N LEU 99.A O no hydrogen 3.040 N/A THR 105.A N LYS 85.A O no hydrogen 2.788 N/A THR 107.A N ALA 87.A O no hydrogen 2.927 N/A THR 107.A OG1 VAL 109.A O no hydrogen 3.559 N/A VAL 109.A N THR 107.A OG1 no hydrogen 2.812 N/A ASP 112.A N LYS 86.A O no hydrogen 2.758 N/A PHE 113.A N LYS 86.A O no hydrogen 3.124 N/A VAL 114.A N ARG 139.A O no hydrogen 2.841 N/A ILE 115.A N TYR 88.A O no hydrogen 2.892 N/A VAL 116.A N ILE 141.A O no hydrogen 2.939 N/A GLY 117.A N VAL 90.A O no hydrogen 2.837 N/A THR 119.A N GLU 118.A OE1 no hydrogen 2.768 N/A ARG 120.A N GLU 92.A OE2 no hydrogen 3.121 N/A SER 121.A N THR 119.A OG1 no hydrogen 3.135 N/A TYR 122.A N THR 119.A O no hydrogen 3.166 N/A MET 126.A N ASN 123.A OD1 no hydrogen 2.944 N/A MET 127.A N ASN 123.A O no hydrogen 3.034 N/A HIS 128.A N TRP 124.A O no hydrogen 2.906 N/A LYS 129.A N ASP 125.A O no hydrogen 2.929 N/A LYS 129.A NZ ASP 108.A OD2 no hydrogen 2.909 N/A ALA 130.A N MET 126.A O no hydrogen 2.891 N/A ALA 131.A N MET 127.A O no hydrogen 2.900 N/A TYR 132.A N HIS 128.A O no hydrogen 2.860 N/A PHE 133.A N LYS 129.A O no hydrogen 2.905 N/A VAL 134.A N ALA 130.A O no hydrogen 2.942 N/A ALA 135.A N ALA 131.A O no hydrogen 2.856 N/A ASN 136.A N TYR 132.A O no hydrogen 3.040 N/A ASN 136.A ND2 TYR 132.A O no hydrogen 2.873 N/A GLY 137.A N VAL 134.A O no hydrogen 3.028 N/A ALA 138.A N PHE 133.A O no hydrogen 2.899 N/A ARG 139.A N ASP 112.A O no hydrogen 2.890 N/A ARG 139.A NH2 GLN 82.A OE1 no hydrogen 2.947 N/A ILE 141.A N VAL 114.A O no hydrogen 2.973 N/A ALA 142.A N PHE 172.A O no hydrogen 2.957 N/A THR 143.A N VAL 116.A O no hydrogen 2.943 N/A THR 143.A OG1 ASN 144.A OD1 no hydrogen 2.800 N/A ASN 144.A ND2 ASP 146.A OD2 no hydrogen 2.834 N/A HIS 148.A ND1 GLY 149.A O no hydrogen 3.160 N/A GLY 149.A N TYR 153.A O no hydrogen 2.779 N/A ARG 150.A NH1 ASP 17.A OD1 no hydrogen 3.458 N/A TYR 153.A N ARG 150.A O no hydrogen 3.143 N/A ALA 155.A N THR 147.A O no hydrogen 2.994 N/A CYS 156.A SG VAL 116.A O no hydrogen 3.371 N/A CYS 156.A SG THR 143.A OG1 no hydrogen 3.709 N/A CYS 156.A SG ASN 144.A O no hydrogen 3.083 N/A GLY 157.A N ASP 146.A O no hydrogen 2.771 N/A ALA 158.A N ALA 155.A O no hydrogen 2.852 N/A LEU 159.A N ALA 155.A O no hydrogen 3.207 N/A CYS 160.A N CYS 156.A O no hydrogen 2.956 N/A CYS 160.A SG CYS 156.A O no hydrogen 3.520 N/A ALA 161.A N GLY 157.A O no hydrogen 3.204 N/A GLU 164.A N CYS 160.A O no hydrogen 2.797 N/A LYS 165.A N ALA 161.A O no hydrogen 2.995 N/A ILE 166.A N GLY 162.A O no hydrogen 3.098 N/A SER 167.A N ILE 163.A O no hydrogen 2.989 N/A SER 167.A OG ILE 163.A O no hydrogen 2.773 N/A GLY 168.A N GLU 164.A O no hydrogen 2.675 N/A ARG 169.A N SER 167.A OG no hydrogen 3.252 N/A ARG 169.A NH1 VAL 134.A O no hydrogen 2.620 N/A ARG 169.A NH1 ALA 138.A O no hydrogen 3.080 N/A PHE 172.A N PHE 140.A O no hydrogen 2.969 N/A VAL 174.A N ALA 142.A O no hydrogen 2.890 N/A GLY 175.A N THR 143.A O no hydrogen 2.817 N/A LYS 176.A N ASN 43.A OD1 no hydrogen 2.788 N/A LYS 176.A NZ ASP 9.A OD1 no hydrogen 2.957 N/A LYS 176.A NZ ASP 206.A OD1 no hydrogen 2.629 N/A SER 178.A N GLY 175.A O no hydrogen 3.054 N/A ILE 182.A N PRO 179.A O no hydrogen 2.950 N/A ARG 183.A N PRO 179.A O no hydrogen 3.185 N/A ALA 184.A N TRP 180.A O no hydrogen 2.851 N/A ALA 185.A N ILE 181.A O no hydrogen 2.947 N/A LEU 186.A N ILE 182.A O no hydrogen 2.888 N/A ASN 187.A N ARG 183.A O no hydrogen 2.930 N/A LYS 188.A N ALA 184.A O no hydrogen 3.025 N/A LYS 188.A NZ SER 66.A O no hydrogen 2.709 N/A MET 189.A N ALA 185.A O no hydrogen 3.195 N/A MET 189.A N LEU 186.A O no hydrogen 2.952 N/A GLN 190.A N ASN 187.A O no hydrogen 3.083 N/A ALA 191.A N LEU 186.A O no hydrogen 2.881 N/A SER 193.A OG GLU 194.A OE2 no hydrogen 2.985 N/A GLU 195.A N HIS 192.A O no hydrogen 3.199 N/A THR 196.A N SER 193.A O no hydrogen 3.157 N/A THR 196.A OG1 HIS 192.A O no hydrogen 2.838 N/A VAL 197.A N ASN 5.A O no hydrogen 3.309 N/A ILE 198.A N GLU 216.A O no hydrogen 3.047 N/A VAL 199.A N ILE 7.A O no hydrogen 2.823 N/A GLY 200.A N ILE 218.A O no hydrogen 3.019 N/A ASN 202.A N ASP 206.A OD2 no hydrogen 3.061 N/A LEU 203.A N SER 225.A OG no hydrogen 2.830 N/A ARG 204.A N ASN 202.A OD1 no hydrogen 2.920 N/A THR 205.A N ASN 202.A O no hydrogen 3.101 N/A ILE 207.A N ASN 202.A O no hydrogen 3.314 N/A LEU 208.A N LEU 203.A O no hydrogen 3.079 N/A ALA 209.A N THR 205.A O no hydrogen 3.054 N/A GLY 210.A N ASP 206.A O no hydrogen 2.980 N/A PHE 211.A N ILE 207.A O no hydrogen 2.850 N/A GLN 212.A N LEU 208.A O no hydrogen 3.074 N/A ALA 213.A N ALA 209.A O no hydrogen 2.998 N/A GLY 214.A N PHE 211.A O no hydrogen 3.069 N/A LEU 215.A N GLY 210.A O no hydrogen 2.865 N/A GLU 216.A N THR 196.A O no hydrogen 3.262 N/A THR 217.A N SER 238.A OG no hydrogen 2.932 N/A ILE 218.A N ILE 198.A O no hydrogen 2.946 N/A LEU 219.A N TRP 239.A O no hydrogen 2.918 N/A VAL 220.A N GLY 200.A O no hydrogen 2.985 N/A LEU 221.A N TYR 241.A O no hydrogen 2.849 N/A LEU 221.A N PRO 242.A O no hydrogen 3.113 N/A SER 222.A OG GLY 12.A O no hydrogen 2.738 N/A VAL 224.A N ASP 201.A OD2 no hydrogen 2.979 N/A SER 225.A N ASP 201.A O no hydrogen 2.926 N/A SER 226.A N ASP 229.A OD2 no hydrogen 2.874 N/A SER 226.A OG ASP 228.A OD1 no hydrogen 2.899 N/A SER 226.A OG ASP 229.A OD2 no hydrogen 3.051 N/A ASP 229.A N SER 226.A O no hydrogen 2.933 N/A ILE 230.A N LEU 227.A O no hydrogen 3.234 N/A ASP 231.A N ASP 228.A O no hydrogen 3.401 N/A MET 233.A N ILE 230.A O no hydrogen 3.183 N/A ARG 236.A NE ILE 230.A O no hydrogen 2.770 N/A ARG 236.A NH2 ILE 230.A O no hydrogen 3.537 N/A ARG 236.A NH2 ASP 231.A O no hydrogen 2.516 N/A SER 238.A N THR 217.A OG1 no hydrogen 3.228 N/A TRP 239.A N THR 217.A O no hydrogen 3.120 N/A TYR 241.A N LEU 219.A O no hydrogen 2.914 N/A ALA 245.A N SER 243.A OG no hydrogen 3.289 N/A GLU 246.A N SER 243.A O no hydrogen 3.388 N/A ILE 247.A N VAL 244.A O no hydrogen 3.084 N/A