Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2c6d_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 7.A N ALA 4.A O no hydrogen 3.013 N/A PHE 8.A N LEU 5.A O no hydrogen 2.953 N/A GLU 9.A N ARG 26.A O no hydrogen 2.823 N/A GLY 11.A N LEU 24.A O no hydrogen 2.769 N/A LEU 14.A N VAL 22.A O no hydrogen 2.640 N/A GLY 15.A N VAL 22.A O no hydrogen 3.241 N/A GLY 17.A N GLY 20.A O no hydrogen 2.844 N/A PHE 19.A N VAL 154.A O no hydrogen 2.862 N/A GLY 20.A N GLY 17.A O no hydrogen 3.057 N/A ASN 21.A N VAL 38.A O no hydrogen 2.975 N/A VAL 22.A N GLY 15.A O no hydrogen 2.758 N/A TYR 23.A N LEU 36.A O no hydrogen 3.010 N/A LEU 24.A N ARG 12.A O no hydrogen 3.021 N/A ALA 25.A N LEU 34.A O no hydrogen 2.826 N/A ARG 26.A N GLU 9.A O no hydrogen 3.032 N/A GLU 27.A N PHE 32.A O no hydrogen 3.288 N/A LYS 28.A N ASP 7.A O no hydrogen 3.024 N/A LYS 28.A NZ PHE 8.A O no hydrogen 3.514 N/A GLN 29.A N GLU 27.A OE2 no hydrogen 2.935 N/A SER 30.A N GLU 27.A OE1 no hydrogen 2.565 N/A LYS 31.A N GLU 27.A O no hydrogen 2.487 N/A LEU 34.A N ALA 25.A O no hydrogen 2.806 N/A ALA 35.A N LEU 85.A O no hydrogen 2.913 N/A LEU 36.A N TYR 23.A O no hydrogen 2.871 N/A LYS 37.A N LEU 83.A O no hydrogen 2.988 N/A LYS 37.A NZ ASP 149.A OD2 no hydrogen 2.789 N/A LYS 37.A NZ TRP 152.A O no hydrogen 3.190 N/A VAL 38.A N ASN 21.A O no hydrogen 2.792 N/A LEU 39.A N VAL 81.A O no hydrogen 2.962 N/A PHE 40.A N PHE 19.A O no hydrogen 3.016 N/A LYS 41.A N THR 79.A O no hydrogen 2.990 N/A LYS 41.A NZ ASP 77.A O no hydrogen 2.660 N/A LYS 41.A NZ ALA 78.A O no hydrogen 3.361 N/A GLN 43.A N PHE 40.A O no hydrogen 3.109 N/A LEU 44.A N PHE 40.A O no hydrogen 3.422 N/A GLU 45.A N LYS 41.A O no hydrogen 3.338 N/A ALA 47.A N GLU 45.A O no hydrogen 3.173 N/A VAL 49.A N ALA 47.A O no hydrogen 2.299 N/A VAL 57.A N ARG 54.A O no hydrogen 2.659 N/A GLU 58.A N ARG 55.A O no hydrogen 2.677 N/A ILE 59.A N ARG 55.A O no hydrogen 3.055 N/A GLN 60.A N GLU 56.A O no hydrogen 3.139 N/A SER 61.A N VAL 57.A O no hydrogen 2.762 N/A SER 61.A OG VAL 57.A O no hydrogen 2.835 N/A SER 61.A OG GLU 58.A O no hydrogen 2.693 N/A HIS 62.A N GLU 58.A O no hydrogen 3.204 N/A HIS 62.A N ILE 59.A O no hydrogen 3.083 N/A LEU 63.A N GLN 60.A O no hydrogen 2.890 N/A ARG 64.A N TYR 121.A OH no hydrogen 2.972 N/A ASN 67.A N HIS 65.A ND1 no hydrogen 2.843 N/A ILE 68.A N HIS 65.A O no hydrogen 3.109 N/A LEU 69.A N ILE 147.A O no hydrogen 3.039 N/A ARG 70.A N GLU 86.A OE2 no hydrogen 2.859 N/A TYR 72.A N ILE 84.A O no hydrogen 2.835 N/A PHE 75.A N TYR 82.A O no hydrogen 3.016 N/A ASP 77.A N ARG 80.A O no hydrogen 2.994 N/A THR 79.A N ASP 77.A OD1 no hydrogen 2.860 N/A ARG 80.A N ASP 77.A OD1 no hydrogen 2.644 N/A VAL 81.A N LEU 39.A O no hydrogen 2.923 N/A TYR 82.A N PHE 75.A O no hydrogen 2.634 N/A TYR 82.A OH ASP 77.A OD2 no hydrogen 2.679 N/A LEU 83.A N LYS 37.A O no hydrogen 2.882 N/A ILE 84.A N GLY 73.A O no hydrogen 2.949 N/A LEU 85.A N ALA 35.A O no hydrogen 2.905 N/A GLU 86.A N ARG 70.A O no hydrogen 2.976 N/A LEU 90.A N LEU 139.A O no hydrogen 3.106 N/A VAL 93.A N LEU 137.A O no hydrogen 2.898 N/A TYR 94.A N PRO 134.A O no hydrogen 3.226 N/A ARG 95.A N THR 92.A OG1 no hydrogen 3.046 N/A GLU 96.A N THR 92.A O no hydrogen 3.209 N/A LEU 97.A N VAL 93.A O no hydrogen 2.882 N/A LEU 97.A N TYR 94.A O no hydrogen 3.037 N/A GLN 98.A N TYR 94.A O no hydrogen 3.016 N/A LYS 99.A N ARG 95.A O no hydrogen 2.989 N/A LEU 100.A N GLU 96.A O no hydrogen 2.976 N/A SER 101.A N LEU 97.A O no hydrogen 2.866 N/A PHE 103.A N PHE 187.A O no hydrogen 2.724 N/A ARG 107.A N ASP 104.A OD1 no hydrogen 3.004 N/A ARG 107.A NH2 TYR 111.A OH no hydrogen 3.138 N/A THR 108.A N ASP 104.A O no hydrogen 2.964 N/A THR 108.A OG1 ASP 104.A O no hydrogen 2.817 N/A ALA 109.A N GLU 105.A O no hydrogen 2.979 N/A THR 110.A N GLN 106.A O no hydrogen 3.155 N/A THR 110.A OG1 GLN 106.A O no hydrogen 2.641 N/A TYR 111.A N ARG 107.A O no hydrogen 3.120 N/A TYR 111.A OH GLU 96.A OE1 no hydrogen 2.568 N/A TYR 111.A OH GLU 96.A OE2 no hydrogen 3.233 N/A ILE 112.A N THR 108.A O no hydrogen 2.955 N/A THR 113.A N ALA 109.A O no hydrogen 2.985 N/A THR 113.A OG1 ALA 109.A O no hydrogen 2.850 N/A THR 113.A OG1 SER 252.A OG no hydrogen 2.985 N/A GLU 114.A N THR 110.A O no hydrogen 2.918 N/A LEU 115.A N TYR 111.A O no hydrogen 3.003 N/A ALA 116.A N ILE 112.A O no hydrogen 2.870 N/A ASN 117.A N THR 113.A O no hydrogen 3.123 N/A ALA 118.A N GLU 114.A O no hydrogen 3.167 N/A LEU 119.A N LEU 115.A O no hydrogen 2.850 N/A SER 120.A N ALA 116.A O no hydrogen 2.862 N/A SER 120.A OG ALA 116.A O no hydrogen 2.597 N/A TYR 121.A N ASN 117.A O no hydrogen 3.121 N/A CYS 122.A N ALA 118.A O no hydrogen 2.893 N/A CYS 122.A SG ALA 118.A O no hydrogen 3.413 N/A HIS 123.A N LEU 119.A O no hydrogen 2.860 N/A HIS 123.A NE2 ASP 176.A OD2 no hydrogen 2.799 N/A SER 124.A N SER 120.A O no hydrogen 3.127 N/A SER 124.A OG TYR 121.A O no hydrogen 2.570 N/A LYS 125.A N CYS 122.A O no hydrogen 2.877 N/A LYS 125.A NZ HIS 62.A O no hydrogen 3.446 N/A LYS 125.A NZ TYR 121.A OH no hydrogen 3.063 N/A ARG 126.A N HIS 123.A O no hydrogen 2.797 N/A VAL 127.A N CYS 122.A O no hydrogen 2.930 N/A ASN 136.A N LYS 133.A O no hydrogen 2.849 N/A LEU 137.A N PRO 134.A O no hydrogen 3.239 N/A LEU 138.A N LYS 146.A O no hydrogen 2.818 N/A LEU 139.A N GLY 91.A O no hydrogen 2.626 N/A GLY 140.A N GLU 144.A O no hydrogen 2.786 N/A ALA 142.A N GLU 144.A OE2 no hydrogen 3.005 N/A GLY 143.A N GLY 140.A O no hydrogen 2.907 N/A GLU 144.A N GLU 144.A OE2 no hydrogen 2.570 N/A LEU 145.A N GLU 114.A OE1 no hydrogen 2.965 N/A LYS 146.A N LEU 138.A O no hydrogen 2.714 N/A LYS 146.A NZ PRO 66.A O no hydrogen 2.813 N/A LYS 146.A NZ GLU 86.A OE1 no hydrogen 3.064 N/A ILE 147.A N ASN 67.A O no hydrogen 2.952 N/A ALA 148.A N ASN 136.A O no hydrogen 2.958 N/A TYR 160.A N THR 157.A O no hydrogen 3.086 N/A TYR 160.A OH GLU 186.A OE1 no hydrogen 3.420 N/A TYR 160.A OH GLU 186.A OE2 no hydrogen 2.972 N/A LEU 161.A N LEU 158.A O no hydrogen 3.096 N/A GLU 164.A N GLU 164.A OE1 no hydrogen 2.755 N/A MET 165.A N PRO 162.A O no hydrogen 2.986 N/A ILE 166.A N PRO 162.A O no hydrogen 3.288 N/A GLU 167.A N PRO 163.A O no hydrogen 2.926 N/A GLY 168.A N MET 165.A O no hydrogen 3.406 N/A ARG 169.A NH2 GLU 167.A OE1 no hydrogen 2.528 N/A LYS 174.A N ASP 172.A OD1 no hydrogen 3.378 N/A LYS 174.A NZ ARG 236.A O no hydrogen 3.055 N/A LYS 174.A NZ PRO 237.A O no hydrogen 3.033 N/A VAL 175.A N ASP 172.A O no hydrogen 3.086 N/A ASP 176.A N GLU 173.A O no hydrogen 3.032 N/A LEU 177.A N LYS 174.A O no hydrogen 3.055 N/A TRP 178.A N LYS 174.A O no hydrogen 3.455 N/A SER 179.A N VAL 175.A O no hydrogen 3.244 N/A SER 179.A OG VAL 175.A O no hydrogen 3.492 N/A LEU 180.A N ASP 176.A O no hydrogen 3.136 N/A GLY 181.A N LEU 177.A O no hydrogen 3.212 N/A VAL 182.A N TRP 178.A O no hydrogen 3.079 N/A LEU 183.A N SER 179.A O no hydrogen 3.042 N/A CYS 184.A N LEU 180.A O no hydrogen 2.999 N/A TYR 185.A N GLY 181.A O no hydrogen 3.185 N/A TYR 185.A OH THR 212.A O no hydrogen 2.874 N/A GLU 186.A N VAL 182.A O no hydrogen 2.893 N/A PHE 187.A N LEU 183.A O no hydrogen 2.765 N/A LEU 188.A N CYS 184.A O no hydrogen 3.216 N/A VAL 189.A N TYR 185.A O no hydrogen 2.826 N/A GLY 190.A N GLU 186.A O no hydrogen 2.748 N/A GLU 201.A N THR 198.A OG1 no hydrogen 3.079 N/A THR 202.A N THR 198.A O no hydrogen 2.985 N/A THR 202.A OG1 THR 198.A O no hydrogen 2.905 N/A TYR 203.A N TYR 199.A O no hydrogen 2.920 N/A LYS 204.A N GLN 200.A O no hydrogen 3.124 N/A LYS 204.A NZ GLU 201.A OE2 no hydrogen 3.234 N/A ARG 205.A N GLU 201.A O no hydrogen 3.057 N/A ARG 205.A NE GLU 201.A OE1 no hydrogen 3.507 N/A ARG 205.A NH1 GLU 195.A O no hydrogen 2.679 N/A ARG 205.A NH2 GLU 201.A OE1 no hydrogen 3.453 N/A ILE 206.A N THR 202.A O no hydrogen 2.951 N/A SER 207.A N TYR 203.A O no hydrogen 2.768 N/A SER 207.A OG GLU 167.A OE2 no hydrogen 3.100 N/A ARG 208.A N LYS 204.A O no hydrogen 2.931 N/A VAL 209.A N ILE 206.A O no hydrogen 3.123 N/A GLU 210.A N ARG 205.A O no hydrogen 2.729 N/A VAL 217.A N PRO 214.A O no hydrogen 3.418 N/A THR 218.A OG1 GLU 105.A OE2 no hydrogen 3.347 N/A ARG 222.A N THR 218.A O no hydrogen 2.826 N/A ARG 222.A NH1 VAL 217.A O no hydrogen 2.910 N/A ASP 223.A N GLU 219.A O no hydrogen 2.892 N/A LEU 224.A N GLY 220.A O no hydrogen 3.209 N/A ILE 225.A N ALA 221.A O no hydrogen 2.981 N/A SER 226.A N ARG 222.A O no hydrogen 3.137 N/A SER 226.A OG ARG 222.A O no hydrogen 2.826 N/A ARG 227.A N ASP 223.A O no hydrogen 3.147 N/A ARG 227.A NE ASP 223.A OD2 no hydrogen 2.854 N/A LEU 228.A N LEU 224.A O no hydrogen 3.125 N/A LEU 228.A N ILE 225.A O no hydrogen 3.183 N/A LEU 229.A N ILE 225.A O no hydrogen 3.030 N/A HIS 231.A ND1 SER 207.A O no hydrogen 3.159 N/A GLN 235.A N ASN 232.A O no hydrogen 3.026 N/A ARG 236.A N PRO 233.A O no hydrogen 3.063 N/A ARG 236.A NE LYS 230.A O no hydrogen 2.793 N/A ARG 236.A NH1 GLU 164.A OE2 no hydrogen 2.840 N/A ARG 236.A NH1 LYS 174.A O no hydrogen 3.003 N/A ARG 236.A NH2 GLU 164.A OE1 no hydrogen 2.786 N/A ARG 236.A NH2 GLU 164.A OE2 no hydrogen 3.296 N/A ARG 236.A NH2 LYS 230.A O no hydrogen 3.212 N/A ARG 236.A NH2 HIS 231.A O no hydrogen 3.535 N/A MET 238.A N GLU 241.A OE2 no hydrogen 2.975 N/A GLU 241.A N MET 238.A O no hydrogen 3.101 N/A VAL 242.A N LEU 239.A O no hydrogen 3.049 N/A LEU 243.A N LEU 239.A O no hydrogen 3.254 N/A GLU 244.A N ARG 240.A O no hydrogen 3.154 N/A HIS 245.A N VAL 242.A O no hydrogen 3.278 N/A HIS 245.A NE2 ASP 223.A OD2 no hydrogen 2.957 N/A TRP 247.A N HIS 245.A ND1 no hydrogen 2.949 N/A TRP 247.A NE1 GLU 105.A OE2 no hydrogen 2.700 N/A THR 249.A N HIS 245.A O no hydrogen 2.944 N/A THR 249.A OG1 HIS 245.A O no hydrogen 3.493 N/A ALA 250.A N PRO 246.A O no hydrogen 3.142 N/A ASN 251.A N TRP 247.A O no hydrogen 3.148 N/A ASN 251.A N ILE 248.A O no hydrogen 3.168 N/A ASN 251.A ND2 TRP 247.A O no hydrogen 2.778 N/A SER 252.A N ILE 248.A O no hydrogen 2.665 N/A SER 252.A OG THR 113.A OG1 no hydrogen 2.985 N/A LYS 254.A N SER 252.A OG no hydrogen 2.884 N/A