Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2cft_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): CYS 4.A N PRO 278.A O no hydrogen 2.964 N/A GLU 5.A N HIS 279.A O no hydrogen 3.053 N/A LEU 7.A N TYR 281.A O no hydrogen 3.088 N/A LEU 12.A N ARG 8.A O no hydrogen 3.273 N/A ARG 13.A N GLY 9.A O no hydrogen 3.027 N/A ASP 14.A N ALA 10.A O no hydrogen 2.785 N/A VAL 15.A N ALA 11.A O no hydrogen 2.811 N/A LEU 16.A N LEU 12.A O no hydrogen 2.994 N/A GLY 17.A N ARG 13.A O no hydrogen 2.895 N/A ARG 18.A N ASP 14.A O no hydrogen 2.980 N/A ALA 19.A N VAL 15.A O no hydrogen 3.124 N/A GLN 20.A N ARG 230.A O no hydrogen 2.732 N/A VAL 22.A N ALA 53.A O no hydrogen 2.875 N/A LEU 23.A N LEU 232.A O no hydrogen 2.730 N/A PHE 24.A N LEU 55.A O no hydrogen 2.779 N/A ASP 25.A N VAL 234.A O no hydrogen 2.908 N/A CYS 26.A N ASP 25.A OD1 no hydrogen 2.797 N/A CYS 26.A SG PHE 24.A O no hydrogen 3.933 N/A GLY 28.A N TRP 31.A O no hydrogen 2.796 N/A VAL 29.A N CYS 26.A O no hydrogen 3.050 N/A LEU 30.A N CYS 26.A O no hydrogen 2.892 N/A ASN 32.A N ARG 35.A O no hydrogen 2.892 N/A ASN 32.A ND2 THR 257.A O no hydrogen 2.773 N/A ARG 35.A N ASN 32.A O no hydrogen 3.013 N/A VAL 37.A N LEU 30.A O no hydrogen 2.942 N/A ALA 40.A N VAL 37.A O no hydrogen 2.979 N/A LEU 43.A N GLY 39.A O no hydrogen 3.054 N/A LEU 44.A N ALA 40.A O no hydrogen 3.184 N/A GLU 45.A N PRO 41.A O no hydrogen 3.032 N/A ARG 46.A N GLU 42.A O no hydrogen 2.936 N/A LEU 47.A N LEU 43.A O no hydrogen 2.861 N/A ALA 48.A N LEU 44.A O no hydrogen 3.060 N/A ARG 49.A N GLU 45.A O no hydrogen 3.168 N/A ALA 50.A N ARG 46.A O no hydrogen 2.856 N/A GLY 51.A N ALA 48.A O no hydrogen 3.180 N/A LYS 52.A N LEU 47.A O no hydrogen 3.002 N/A LYS 52.A NZ LEU 16.A O no hydrogen 3.013 N/A LYS 52.A NZ GLY 17.A O no hydrogen 2.948 N/A LYS 52.A NZ ALA 19.A O no hydrogen 2.971 N/A ALA 53.A N GLN 20.A O no hydrogen 3.306 N/A LEU 55.A N VAL 22.A O no hydrogen 3.023 N/A PHE 56.A N GLN 84.A O no hydrogen 2.992 N/A VAL 57.A N PHE 24.A O no hydrogen 2.763 N/A SER 58.A N PHE 86.A O no hydrogen 2.868 N/A ASN 59.A ND2 ASP 177.A OD2 no hydrogen 3.078 N/A ASN 59.A ND2 LYS 211.A O no hydrogen 2.848 N/A ASN 60.A N SER 58.A OG no hydrogen 3.147 N/A ARG 62.A N ASN 60.A OD1 no hydrogen 2.902 N/A ARG 65.A N GLU 119.A OE1 no hydrogen 2.755 N/A ARG 65.A NE LEU 85.A O no hydrogen 2.813 N/A ARG 65.A NH2 LEU 85.A O no hydrogen 2.964 N/A LEU 68.A N ALA 64.A O no hydrogen 2.994 N/A ALA 69.A N ARG 65.A O no hydrogen 2.900 N/A LEU 70.A N PRO 66.A O no hydrogen 3.259 N/A ARG 71.A N GLU 67.A O no hydrogen 3.093 N/A ARG 71.A NH1 GLU 34.A OE1 no hydrogen 3.088 N/A ARG 71.A NH1 GLU 34.A OE2 no hydrogen 3.322 N/A ARG 71.A NH2 GLY 33.A O no hydrogen 2.788 N/A PHE 72.A N LEU 68.A O no hydrogen 3.147 N/A ALA 73.A N ALA 69.A O no hydrogen 3.254 N/A ARG 74.A N LEU 70.A O no hydrogen 3.050 N/A LEU 75.A N ARG 71.A O no hydrogen 3.176 N/A LEU 75.A N PHE 72.A O no hydrogen 3.209 N/A GLY 76.A N ALA 73.A O no hydrogen 3.022 N/A PHE 77.A N PHE 72.A O no hydrogen 2.976 N/A ARG 81.A N GLN 84.A OE1 no hydrogen 2.867 N/A GLN 84.A N ARG 81.A O no hydrogen 2.816 N/A GLN 84.A NE2 ALA 54.A O no hydrogen 2.873 N/A LEU 85.A N ALA 82.A O no hydrogen 3.108 N/A PHE 86.A N PHE 56.A O no hydrogen 2.835 N/A SER 88.A N SER 58.A O no hydrogen 2.946 N/A SER 88.A OG ASN 59.A O no hydrogen 2.672 N/A LEU 90.A N SER 87.A OG no hydrogen 3.080 N/A CYS 91.A N SER 87.A O no hydrogen 3.008 N/A CYS 91.A SG SER 87.A O no hydrogen 3.506 N/A ALA 92.A N SER 88.A O no hydrogen 2.883 N/A ALA 93.A N ALA 89.A O no hydrogen 3.093 N/A ARG 94.A N LEU 90.A O no hydrogen 3.102 N/A ARG 94.A NH1 ASN 223.A OD1 no hydrogen 3.160 N/A LEU 95.A N CYS 91.A O no hydrogen 2.800 N/A LEU 96.A N ALA 92.A O no hydrogen 2.980 N/A ARG 97.A N ALA 93.A O no hydrogen 3.040 N/A ARG 97.A NH1 ALA 123.A O no hydrogen 2.782 N/A GLN 98.A N ARG 94.A O no hydrogen 3.034 N/A ARG 99.A N LEU 96.A O no hydrogen 3.262 N/A LEU 100.A N LEU 96.A O no hydrogen 2.961 N/A ALA 107.A N ARG 140.A O no hydrogen 2.900 N/A VAL 108.A N ARG 126.A O no hydrogen 2.853 N/A PHE 109.A N ALA 143.A O no hydrogen 2.832 N/A LEU 111.A N LEU 145.A O no hydrogen 2.865 N/A ARG 117.A N GLY 113.A O no hydrogen 3.053 N/A ARG 117.A NH2 VAL 110.A O no hydrogen 2.882 N/A ARG 117.A NH2 GLY 112.A O no hydrogen 3.397 N/A ALA 118.A N GLU 114.A O no hydrogen 2.884 N/A GLU 119.A N GLY 115.A O no hydrogen 3.075 N/A LEU 120.A N LEU 116.A O no hydrogen 2.967 N/A ARG 121.A N ARG 117.A O no hydrogen 2.920 N/A ARG 121.A NE ASP 130.A OD1 no hydrogen 3.063 N/A ARG 121.A NH2 ASP 130.A OD1 no hydrogen 3.142 N/A ALA 122.A N ALA 118.A O no hydrogen 2.975 N/A ALA 123.A N GLU 119.A O no hydrogen 3.291 N/A ALA 123.A N LEU 120.A O no hydrogen 3.176 N/A GLY 124.A N ARG 121.A O no hydrogen 2.975 N/A LEU 125.A N LEU 120.A O no hydrogen 3.144 N/A ARG 126.A NH2 PRO 131.A O no hydrogen 2.738 N/A LEU 127.A N ASP 130.A OD2 no hydrogen 3.079 N/A ALA 128.A N VAL 108.A O no hydrogen 2.862 N/A ASP 130.A N LEU 127.A O no hydrogen 2.947 N/A GLY 136.A N ALA 133.A O no hydrogen 3.041 N/A ARG 140.A NH2 ASP 166.A OD2 no hydrogen 2.782 N/A ARG 142.A N ALA 107.A O no hydrogen 2.877 N/A VAL 144.A N LEU 170.A O no hydrogen 2.839 N/A LEU 145.A N PHE 109.A O no hydrogen 2.897 N/A VAL 146.A N VAL 172.A O no hydrogen 2.797 N/A GLY 147.A N LEU 111.A O no hydrogen 2.792 N/A TYR 148.A N SER 61.A OG no hydrogen 3.056 N/A TYR 148.A OH GLU 150.A OE2 no hydrogen 2.885 N/A TYR 148.A OH THR 188.A OG1 no hydrogen 2.848 N/A HIS 151.A N ASP 149.A OD1 no hydrogen 2.918 N/A PHE 152.A N ASP 149.A O no hydrogen 3.088 N/A LYS 156.A N SER 153.A OG no hydrogen 3.036 N/A LYS 156.A NZ HIS 151.A O no hydrogen 2.684 N/A LEU 157.A N SER 153.A O no hydrogen 3.036 N/A ARG 158.A N PHE 154.A O no hydrogen 2.844 N/A GLU 159.A N ALA 155.A O no hydrogen 2.972 N/A ALA 160.A N LYS 156.A O no hydrogen 2.820 N/A CYS 161.A N LEU 157.A O no hydrogen 2.933 N/A CYS 161.A SG LEU 157.A O no hydrogen 3.420 N/A ALA 162.A N ARG 158.A O no hydrogen 3.031 N/A HIS 163.A N GLU 159.A O no hydrogen 3.165 N/A HIS 163.A NE2 GLU 159.A OE2 no hydrogen 3.234 N/A LEU 164.A N ALA 160.A O no hydrogen 3.071 N/A ARG 165.A N ALA 162.A O no hydrogen 3.290 N/A ASP 166.A N HIS 163.A O no hydrogen 3.336 N/A GLU 168.A N ASP 166.A OD1 no hydrogen 2.948 N/A CYS 169.A N ASP 166.A O no hydrogen 2.880 N/A CYS 169.A SG VAL 141.A O no hydrogen 3.877 N/A CYS 169.A SG LEU 170.A O no hydrogen 3.651 N/A LEU 170.A N ARG 142.A O no hydrogen 3.016 N/A VAL 172.A N VAL 144.A O no hydrogen 2.918 N/A ALA 173.A N LEU 207.A O no hydrogen 2.872 N/A THR 174.A N VAL 146.A O no hydrogen 2.867 N/A THR 174.A OG1 VAL 146.A O no hydrogen 3.550 N/A THR 174.A OG1 ASP 175.A OD2 no hydrogen 2.818 N/A ARG 176.A NH1 GLU 199.A OE1 no hydrogen 2.906 N/A ARG 176.A NH1 GLU 199.A OE2 no hydrogen 3.321 N/A ARG 176.A NH2 GLU 199.A OE2 no hydrogen 2.648 N/A ASP 177.A N ASP 175.A OD1 no hydrogen 2.949 N/A HIS 180.A N THR 188.A O no hydrogen 2.869 N/A LEU 182.A N SER 186.A O no hydrogen 2.803 N/A GLY 185.A N LEU 182.A O no hydrogen 3.065 N/A SER 186.A N ASP 184.A OD1 no hydrogen 3.087 N/A SER 186.A OG ASP 184.A OD1 no hydrogen 2.654 N/A THR 188.A N HIS 180.A O no hydrogen 2.901 N/A THR 188.A OG1 TYR 148.A OH no hydrogen 2.848 N/A GLY 190.A N PRO 178.A O no hydrogen 2.885 N/A THR 191.A OG1 ASP 175.A OD2 no hydrogen 3.047 N/A GLY 192.A N ASP 177.A O no hydrogen 2.906 N/A SER 193.A N GLY 190.A O no hydrogen 2.976 N/A SER 193.A OG GLY 190.A O no hydrogen 2.727 N/A ALA 195.A N THR 191.A O no hydrogen 2.747 N/A ALA 196.A N GLY 192.A O no hydrogen 2.938 N/A ALA 197.A N SER 193.A O no hydrogen 3.268 N/A VAL 198.A N LEU 194.A O no hydrogen 3.018 N/A GLU 199.A N ALA 195.A O no hydrogen 2.849 N/A THR 200.A N ALA 196.A O no hydrogen 2.965 N/A THR 200.A OG1 ALA 196.A O no hydrogen 2.811 N/A ALA 201.A N ALA 197.A O no hydrogen 2.965 N/A SER 202.A N VAL 198.A O no hydrogen 2.973 N/A SER 202.A OG VAL 198.A O no hydrogen 2.727 N/A ARG 204.A N GLU 199.A O no hydrogen 3.226 N/A ARG 204.A NE LEU 164.A O no hydrogen 3.416 N/A ARG 204.A NH1 CYS 169.A O no hydrogen 2.842 N/A ARG 204.A NH2 LEU 164.A O no hydrogen 2.913 N/A ARG 204.A NH2 CYS 169.A O no hydrogen 2.732 N/A ALA 206.A N GLU 199.A OE2 no hydrogen 2.752 N/A LEU 207.A N LEU 171.A O no hydrogen 2.881 N/A VAL 209.A N ALA 173.A O no hydrogen 2.969 N/A GLY 210.A N THR 174.A O no hydrogen 2.780 N/A LYS 211.A NZ VAL 57.A O no hydrogen 3.052 N/A LYS 211.A NZ ASP 241.A OD1 no hydrogen 2.773 N/A SER 213.A N GLY 210.A O no hydrogen 2.795 N/A SER 213.A OG VAL 208.A O no hydrogen 2.956 N/A TYR 215.A N SER 213.A OG no hydrogen 3.103 N/A TYR 215.A OH GLN 98.A OE1 no hydrogen 2.970 N/A MET 216.A N SER 213.A O no hydrogen 3.107 N/A GLU 218.A N PRO 214.A O no hydrogen 3.167 N/A CYS 219.A N TYR 215.A O no hydrogen 2.881 N/A ILE 220.A N MET 216.A O no hydrogen 3.013 N/A THR 221.A N PHE 217.A O no hydrogen 2.890 N/A THR 221.A OG1 PHE 217.A O no hydrogen 2.804 N/A THR 221.A OG1 GLU 218.A O no hydrogen 3.564 N/A ALA 229.A N ASP 227.A OD1 no hydrogen 3.024 N/A ARG 230.A N ASP 227.A O no hydrogen 2.756 N/A ARG 230.A NE ARG 18.A O no hydrogen 2.781 N/A ARG 230.A NH2 ARG 18.A O no hydrogen 2.742 N/A THR 231.A N PRO 228.A O no hydrogen 3.203 N/A THR 231.A OG1 ASP 227.A O no hydrogen 2.752 N/A LEU 232.A N GLY 21.A O no hydrogen 3.047 N/A MET 233.A N THR 251.A O no hydrogen 2.814 N/A VAL 234.A N LEU 23.A O no hydrogen 2.956 N/A GLY 235.A N VAL 253.A O no hydrogen 3.024 N/A ASP 236.A N ASP 25.A OD2 no hydrogen 3.176 N/A ARG 237.A N ASP 241.A OD2 no hydrogen 2.956 N/A ARG 237.A NH1.A TRP 179.A O no hydrogen 2.796 N/A ARG 237.A NH1.B TRP 179.A O no hydrogen 3.415 N/A ARG 237.A NH2.A TRP 179.A O no hydrogen 3.174 N/A ARG 237.A NH2.B TRP 179.A O no hydrogen 3.052 N/A LEU 238.A N SER 260.A OG no hydrogen 2.901 N/A THR 240.A N ARG 237.A O no hydrogen 3.208 N/A ASP 241.A N ARG 237.A O no hydrogen 2.825 N/A ILE 242.A N ARG 237.A O no hydrogen 3.261 N/A LEU 243.A N LEU 238.A O no hydrogen 3.076 N/A PHE 244.A N THR 240.A O no hydrogen 3.040 N/A GLY 245.A N ASP 241.A O no hydrogen 3.017 N/A HIS 246.A N ILE 242.A O no hydrogen 3.046 N/A HIS 246.A NE2 VAL 277.A O no hydrogen 2.675 N/A ARG 247.A N LEU 243.A O no hydrogen 2.909 N/A ARG 247.A NH1 PRO 212.A O no hydrogen 2.909 N/A CYS 248.A N PHE 244.A O no hydrogen 2.969 N/A CYS 248.A SG PHE 244.A O no hydrogen 3.324 N/A GLY 249.A N HIS 246.A O no hydrogen 3.203 N/A MET 250.A N GLY 245.A O no hydrogen 2.831 N/A THR 251.A N THR 231.A O no hydrogen 3.299 N/A THR 252.A N HIS 279.A ND1 no hydrogen 3.082 N/A THR 252.A OG1 HIS 279.A ND1 no hydrogen 3.184 N/A VAL 253.A N MET 233.A O no hydrogen 2.819 N/A LEU 254.A N TYR 280.A O no hydrogen 2.860 N/A THR 255.A N GLY 235.A O no hydrogen 3.010 N/A LEU 256.A N VAL 282.A O no hydrogen 3.081 N/A LEU 256.A N GLU 283.A O no hydrogen 3.325 N/A THR 257.A OG1 GLY 28.A O no hydrogen 2.658 N/A VAL 259.A N ASP 236.A OD2 no hydrogen 2.828 N/A SER 260.A N ASP 236.A O no hydrogen 2.824 N/A ARG 261.A N GLU 264.A OE2 no hydrogen 2.890 N/A ARG 261.A NH1 GLY 258.A O no hydrogen 2.934 N/A ARG 261.A NH2 GLY 258.A O no hydrogen 3.106 N/A GLU 264.A N ARG 261.A O no hydrogen 2.996 N/A ALA 265.A N ARG 261.A O no hydrogen 3.262 N/A GLN 266.A N LEU 262.A O no hydrogen 2.915 N/A ALA 267.A N GLU 263.A O no hydrogen 2.935 N/A TYR 268.A N GLU 264.A O no hydrogen 2.999 N/A TYR 268.A OH GLU 239.A OE2 no hydrogen 2.879 N/A LEU 269.A N ALA 265.A O no hydrogen 2.978 N/A ALA 270.A N GLN 266.A O no hydrogen 2.903 N/A ALA 271.A N ALA 267.A O no hydrogen 2.997 N/A GLY 272.A N LEU 269.A O no hydrogen 3.005 N/A GLN 273.A N TYR 268.A O no hydrogen 2.877 N/A LEU 276.A N GLN 273.A O no hydrogen 3.046 N/A VAL 277.A N HIS 274.A O no hydrogen 3.153 N/A HIS 279.A N THR 252.A OG1 no hydrogen 2.934 N/A TYR 280.A N THR 252.A O no hydrogen 2.966 N/A TYR 281.A N GLU 5.A O no hydrogen 2.929 N/A VAL 282.A N LEU 254.A O no hydrogen 2.852 N/A SER 284.A N ASP 287.A OD2 no hydrogen 3.153 N/A ALA 286.A N SER 284.A OG no hydrogen 3.278 N/A ASP 287.A N SER 284.A O no hydrogen 2.905 N/A LEU 288.A N ILE 285.A O no hydrogen 2.922 N/A THR 289.A N ALA 286.A O no hydrogen 3.415 N/A THR 289.A OG1 ALA 286.A O no hydrogen 3.500 N/A GLY 291.A N LEU 288.A O no hydrogen 2.935 N/A LEU 292.A N THR 289.A O no hydrogen 3.084 N/A GLU 293.A N GLU 290.A O no hydrogen 3.382 N/A