Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2cm3_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 5.A N PHE 1.A O no hydrogen 3.153 N/A LYS 6.A N GLU 2.A O no hydrogen 3.012 N/A SER 7.A N GLN 3.A O no hydrogen 2.683 N/A SER 7.A OG GLN 3.A O no hydrogen 2.630 N/A SER 7.A OG SER 9.A OG no hydrogen 3.126 N/A GLY 8.A N ASP 5.A O no hydrogen 3.129 N/A SER 9.A N ILE 4.A O no hydrogen 2.816 N/A SER 9.A OG SER 7.A O no hydrogen 3.401 N/A SER 9.A OG SER 7.A OG no hydrogen 3.126 N/A TRP 10.A NE1 ASP 5.A OD1 no hydrogen 2.960 N/A ILE 13.A N SER 9.A O no hydrogen 2.882 N/A TYR 14.A N TRP 10.A O no hydrogen 2.727 N/A TYR 14.A OH ILE 255.A O no hydrogen 2.711 N/A GLN 15.A N ALA 11.A O no hydrogen 2.816 N/A ASP 16.A N ALA 12.A O no hydrogen 2.918 N/A ILE 17.A N ILE 13.A O no hydrogen 3.140 N/A ILE 17.A N TYR 14.A O no hydrogen 2.991 N/A ARG 18.A N TYR 14.A O no hydrogen 3.139 N/A ARG 18.A NE TYR 14.A OH no hydrogen 2.886 N/A ARG 18.A NH2 TYR 14.A OH no hydrogen 3.144 N/A ARG 18.A NH2 GLN 256.A O no hydrogen 3.307 N/A HIS 19.A N GLN 15.A O no hydrogen 3.021 N/A GLU 20.A N ASP 16.A O no hydrogen 2.939 N/A ALA 21.A N ILE 17.A O no hydrogen 2.799 N/A CYS 26.A SG PHE 24.A O no hydrogen 3.856 N/A CYS 26.A SG SER 44.A O no hydrogen 3.955 N/A CYS 26.A SG PRO 45.A O no hydrogen 3.205 N/A ARG 27.A N ASP 47.A OD2 no hydrogen 2.581 N/A VAL 28.A N ASP 47.A OD1 no hydrogen 3.061 N/A LYS 30.A N CYS 26.A O no hydrogen 3.157 N/A LYS 30.A N ARG 27.A O no hydrogen 2.921 N/A LYS 30.A NZ ARG 41.A O no hydrogen 2.662 N/A LYS 30.A NZ SER 44.A OG no hydrogen 3.391 N/A LEU 31.A N VAL 28.A O no hydrogen 2.885 N/A ASN 34.A N LEU 31.A O no hydrogen 2.947 N/A LYS 35.A N PRO 32.A O no hydrogen 3.322 N/A LYS 35.A NZ PRO 32.A O no hydrogen 3.567 N/A ARG 37.A N ASN 34.A O no hydrogen 3.181 N/A ARG 37.A NH1 TYR 60.A O no hydrogen 2.989 N/A ASN 38.A N LYS 35.A O no hydrogen 3.344 N/A ASN 38.A ND2 ALA 29.A O no hydrogen 2.933 N/A ARG 39.A N GLN 79.A OE1 no hydrogen 2.886 N/A ARG 39.A NE GLY 80.A O no hydrogen 3.119 N/A ARG 39.A NH2 GLY 80.A O no hydrogen 3.231 N/A ARG 39.A NH2 PRO 81.A O no hydrogen 2.673 N/A TYR 40.A OH SER 210.A OG no hydrogen 3.132 N/A VAL 43.A N TYR 40.A O no hydrogen 3.141 N/A ASP 47.A N PRO 25.A O no hydrogen 2.706 N/A SER 49.A OG PHE 250.A O no hydrogen 2.461 N/A ARG 50.A NH1 ASP 59.A O no hydrogen 3.391 N/A ARG 50.A NH1 ASP 59.A OD1 no hydrogen 3.023 N/A ARG 50.A NH2 ASP 59.A OD1 no hydrogen 3.010 N/A ARG 50.A NH2 ASP 59.A OD2 no hydrogen 3.542 N/A ILE 51.A N ALA 63.A O no hydrogen 2.945 N/A LEU 53.A N ASP 59.A O no hydrogen 2.864 N/A HIS 54.A N GLU 95.A OE1 no hydrogen 2.648 N/A HIS 54.A N GLU 95.A OE2 no hydrogen 3.174 N/A GLN 55.A N LEU 53.A O no hydrogen 2.799 N/A GLN 55.A NE2 GLU 91.A OE1 no hydrogen 2.837 N/A GLN 55.A NE2 GLU 91.A OE2 no hydrogen 3.211 N/A TYR 60.A N ASN 58.A OD1 no hydrogen 2.669 N/A TYR 60.A OH ASN 38.A OD1 no hydrogen 2.551 N/A ASN 62.A ND2 ASN 38.A OD1 no hydrogen 2.837 N/A ASN 62.A ND2 VAL 43.A O no hydrogen 2.935 N/A SER 64.A N LEU 77.A O no hydrogen 2.644 N/A LEU 65.A N SER 49.A O no hydrogen 2.690 N/A ILE 66.A N TYR 75.A O no hydrogen 2.732 N/A LYS 67.A NZ GLU 69.A OE1 no hydrogen 2.926 N/A LYS 67.A NZ GLU 69.A OE2 no hydrogen 3.067 N/A MET 68.A N ARG 73.A O no hydrogen 2.899 N/A ARG 73.A N MET 68.A O no hydrogen 3.327 N/A ARG 73.A NH1 ASP 223.A OD1 no hydrogen 2.983 N/A ARG 73.A NH1 ASP 223.A OD2 no hydrogen 3.075 N/A TYR 75.A N ILE 66.A O no hydrogen 2.859 N/A TYR 75.A OH ASP 223.A OD2 no hydrogen 2.686 N/A TYR 75.A OH THR 224.A OG1 no hydrogen 2.665 N/A ILE 76.A N VAL 205.A O no hydrogen 2.948 N/A LEU 77.A N SER 64.A O no hydrogen 2.895 N/A THR 78.A N VAL 207.A O no hydrogen 3.018 N/A THR 78.A OG1 ASN 62.A O no hydrogen 2.559 N/A GLN 79.A NE2 ARG 37.A O no hydrogen 2.937 N/A GLY 80.A N SER 210.A O no hydrogen 2.893 N/A LEU 82.A N THR 85.A OG1 no hydrogen 2.608 N/A ASN 84.A ND2 ASN 36.A O no hydrogen 3.278 N/A THR 85.A N LEU 82.A O no hydrogen 2.826 N/A THR 85.A OG1 LEU 82.A O no hydrogen 3.353 N/A CYS 86.A SG LEU 82.A O no hydrogen 3.353 N/A PHE 89.A N THR 85.A O no hydrogen 2.666 N/A TRP 90.A N CYS 86.A O no hydrogen 3.060 N/A TRP 90.A NE1 TYR 118.A O no hydrogen 2.899 N/A GLU 91.A N GLY 87.A O no hydrogen 2.740 N/A MET 92.A N HIS 88.A O no hydrogen 2.843 N/A VAL 93.A N PHE 89.A O no hydrogen 3.134 N/A TRP 94.A N TRP 90.A O no hydrogen 3.090 N/A GLU 95.A N GLU 91.A O no hydrogen 2.763 N/A GLN 96.A N MET 92.A O no hydrogen 2.771 N/A LYS 97.A N TRP 94.A O no hydrogen 2.960 N/A SER 98.A N VAL 93.A O no hydrogen 3.069 N/A SER 98.A OG PRO 204.A O no hydrogen 2.854 N/A ARG 99.A NH1 GLU 164.A O no hydrogen 2.931 N/A ARG 99.A NH1 GLU 164.A OE2 no hydrogen 2.964 N/A VAL 101.A N LEU 166.A O no hydrogen 2.914 N/A VAL 102.A N VAL 206.A O no hydrogen 2.665 N/A MET 103.A N PHE 168.A O no hydrogen 2.776 N/A LEU 104.A N HIS 208.A O no hydrogen 2.831 N/A ASN 105.A ND2 ARG 106.A O no hydrogen 2.941 N/A ARG 106.A N GLU 109.A OE2 no hydrogen 2.439 N/A LYS 114.A NZ TYR 40.A OH no hydrogen 3.042 N/A CYS 115.A SG ALA 116.A O no hydrogen 3.079 N/A ALA 116.A N PRO 81.A O no hydrogen 3.060 N/A GLN 117.A NE2 TRP 119.A O no hydrogen 2.514 N/A TYR 118.A OH HIS 167.A NE2 no hydrogen 2.802 N/A TYR 118.A OH HIS 208.A NE2 no hydrogen 2.513 N/A GLU 123.A N GLU 123.A OE1 no hydrogen 2.763 N/A GLU 124.A N GLU 124.A OE1 no hydrogen 2.624 N/A LYS 125.A N LYS 122.A O no hydrogen 2.865 N/A GLU 126.A N GLU 126.A OE1 no hydrogen 2.387 N/A MET 127.A N LEU 136.A O no hydrogen 2.838 N/A PHE 129.A N LEU 134.A O no hydrogen 2.745 N/A THR 132.A OG1 GLY 87.A O no hydrogen 3.072 N/A ASN 133.A N GLU 130.A O no hydrogen 3.191 N/A LEU 134.A N PHE 129.A O no hydrogen 2.966 N/A LYS 135.A N GLU 155.A O no hydrogen 2.884 N/A LEU 136.A N MET 127.A O no hydrogen 2.823 N/A THR 137.A N GLU 153.A O no hydrogen 2.910 N/A ILE 139.A N GLN 151.A O no hydrogen 2.770 N/A SER 140.A N GLN 151.A O no hydrogen 3.364 N/A ASP 142.A N VAL 149.A O no hydrogen 2.798 N/A LYS 144.A N TYR 147.A O no hydrogen 2.886 N/A LYS 144.A NZ TYR 147.A OH no hydrogen 2.637 N/A THR 148.A N HIS 169.A O no hydrogen 2.793 N/A VAL 149.A N ASP 142.A O no hydrogen 3.012 N/A ARG 150.A N HIS 167.A O no hydrogen 2.760 N/A ARG 150.A NE GLU 141.A OE1 no hydrogen 3.211 N/A ARG 150.A NH1 HIS 167.A ND1 no hydrogen 3.084 N/A ARG 150.A NH1 HIS 169.A ND1 no hydrogen 3.480 N/A GLN 151.A N SER 140.A O no hydrogen 2.942 N/A LEU 152.A N ILE 165.A O no hydrogen 2.937 N/A GLU 153.A N THR 137.A O no hydrogen 2.854 N/A LEU 154.A N ARG 163.A O no hydrogen 2.772 N/A GLU 155.A N LYS 135.A O no hydrogen 2.586 N/A ASN 156.A N GLU 161.A O no hydrogen 2.819 N/A LEU 157.A N ASN 133.A O no hydrogen 3.199 N/A THR 158.A OG1 ASN 133.A OD1 no hydrogen 3.140 N/A THR 159.A N ASN 156.A O no hydrogen 2.801 N/A THR 159.A OG1 ASN 156.A O no hydrogen 3.383 N/A THR 159.A OG1 GLU 161.A OE2 no hydrogen 2.633 N/A GLN 160.A NE2 GLU 155.A OE2 no hydrogen 2.854 N/A ARG 163.A N LEU 154.A O no hydrogen 2.842 N/A ARG 163.A NH1 TRP 94.A O no hydrogen 2.867 N/A ILE 165.A N LEU 152.A O no hydrogen 2.813 N/A LEU 166.A N ARG 99.A O no hydrogen 2.917 N/A HIS 167.A N ARG 150.A O no hydrogen 2.861 N/A HIS 167.A NE2 TYR 118.A OH no hydrogen 2.802 N/A PHE 168.A N VAL 101.A O no hydrogen 2.811 N/A HIS 169.A N THR 148.A O no hydrogen 2.709 N/A HIS 169.A NE2 ASN 105.A O no hydrogen 2.629 N/A TYR 170.A N MET 103.A O no hydrogen 2.886 N/A TYR 170.A OH SER 184.A OG no hydrogen 2.743 N/A THR 171.A N TYR 146.A O no hydrogen 3.226 N/A THR 172.A OG1 TYR 146.A O no hydrogen 3.558 N/A ALA 183.A N SER 181.A OG no hydrogen 3.258 N/A SER 184.A OG TYR 170.A OH no hydrogen 2.743 N/A LEU 186.A N PRO 182.A O no hydrogen 2.762 N/A ASN 187.A N ALA 183.A O no hydrogen 3.166 N/A ASN 187.A ND2 TYR 146.A OH no hydrogen 3.081 N/A PHE 188.A N SER 184.A O no hydrogen 2.742 N/A LEU 189.A N PHE 185.A O no hydrogen 3.122 N/A PHE 190.A N LEU 186.A O no hydrogen 3.033 N/A LYS 191.A N ASN 187.A O no hydrogen 2.935 N/A VAL 192.A N PHE 188.A O no hydrogen 2.976 N/A ARG 193.A N LEU 189.A O no hydrogen 2.726 N/A ARG 193.A NE ASP 223.A OD1 no hydrogen 2.852 N/A ARG 193.A NH2 ASP 223.A O no hydrogen 3.181 N/A ARG 193.A NH2 ASP 223.A OD1 no hydrogen 2.789 N/A GLU 194.A N PHE 190.A O no hydrogen 2.692 N/A SER 195.A N LYS 191.A O no hydrogen 2.878 N/A SER 195.A N VAL 192.A O no hydrogen 3.297 N/A SER 195.A OG VAL 192.A O no hydrogen 2.793 N/A SER 195.A OG SER 197.A OG no hydrogen 2.508 N/A GLY 196.A N ARG 193.A O no hydrogen 3.012 N/A SER 197.A N SER 195.A OG no hydrogen 3.138 N/A SER 197.A OG SER 195.A OG no hydrogen 2.508 N/A SER 199.A N GLY 196.A O no hydrogen 3.274 N/A SER 199.A OG GLY 196.A O no hydrogen 2.965 N/A SER 199.A OG GLU 201.A OE1 no hydrogen 3.371 N/A HIS 202.A N SER 199.A O no hydrogen 3.304 N/A GLY 203.A N LYS 97.A O no hydrogen 2.880 N/A VAL 206.A N GLY 100.A O no hydrogen 2.941 N/A VAL 207.A N ILE 76.A O no hydrogen 2.734 N/A HIS 208.A N VAL 102.A O no hydrogen 2.903 N/A HIS 208.A ND1 CYS 209.A O no hydrogen 2.877 N/A HIS 208.A NE2 TYR 118.A OH no hydrogen 2.513 N/A CYS 209.A SG SER 216.A OG no hydrogen 3.218 N/A SER 210.A OG TYR 40.A OH no hydrogen 3.132 N/A SER 210.A OG LYS 114.A O no hydrogen 2.424 N/A ARG 215.A NH1 LEU 104.A O no hydrogen 3.234 N/A ARG 215.A NH1 GLU 109.A OE1 no hydrogen 2.550 N/A ARG 215.A NH1 GLU 109.A OE2 no hydrogen 2.825 N/A ARG 215.A NH2 GLU 109.A OE1 no hydrogen 2.477 N/A THR 218.A N GLY 214.A O no hydrogen 3.078 N/A THR 218.A OG1 GLY 214.A O no hydrogen 3.050 N/A PHE 219.A N ARG 215.A O no hydrogen 3.021 N/A CYS 220.A N SER 216.A O no hydrogen 3.151 N/A CYS 220.A SG SER 216.A O no hydrogen 3.407 N/A LEU 221.A N GLY 217.A O no hydrogen 2.804 N/A ALA 222.A N THR 218.A O no hydrogen 2.860 N/A ASP 223.A N PHE 219.A O no hydrogen 3.070 N/A THR 224.A N CYS 220.A O no hydrogen 2.863 N/A THR 224.A OG1 TYR 75.A OH no hydrogen 2.665 N/A THR 224.A OG1 CYS 220.A O no hydrogen 2.912 N/A CYS 225.A N LEU 221.A O no hydrogen 2.965 N/A CYS 225.A SG LEU 221.A O no hydrogen 3.179 N/A LEU 226.A N ALA 222.A O no hydrogen 2.990 N/A LEU 227.A N ASP 223.A O no hydrogen 2.980 N/A LEU 228.A N THR 224.A O no hydrogen 2.951 N/A MET 229.A N CYS 225.A O no hydrogen 2.728 N/A ASP 230.A N LEU 227.A O no hydrogen 2.991 N/A LYS 231.A N LEU 228.A O no hydrogen 2.962 N/A LYS 231.A NZ ALA 71.A O no hydrogen 2.881 N/A LYS 231.A NZ GLN 72.A OE1 no hydrogen 3.212 N/A ARG 232.A NE GLU 70.A OE2 no hydrogen 2.518 N/A ARG 232.A NH1 SER 237.A OG no hydrogen 2.917 N/A ARG 232.A NH2 GLU 70.A OE1 no hydrogen 2.678 N/A ARG 232.A NH2 GLU 70.A OE2 no hydrogen 3.083 N/A SER 236.A N ASP 234.A OD2 no hydrogen 3.276 N/A SER 236.A OG SER 236.A O no hydrogen 2.539 N/A LYS 241.A N ASP 239.A OD1 no hydrogen 3.214 N/A LYS 241.A NZ ASP 16.A OD2 no hydrogen 3.175 N/A LYS 241.A NZ GLU 20.A OE2 no hydrogen 2.686 N/A LYS 242.A N ASP 239.A OD2 no hydrogen 2.935 N/A VAL 243.A N ASP 239.A O no hydrogen 2.899 N/A LEU 244.A N ILE 240.A O no hydrogen 2.843 N/A LEU 245.A N LYS 241.A O no hydrogen 3.033 N/A GLU 246.A N LYS 242.A O no hydrogen 2.991 N/A MET 247.A N VAL 243.A O no hydrogen 2.904 N/A ARG 248.A N LEU 244.A O no hydrogen 2.751 N/A ARG 248.A NE LEU 254.A O no hydrogen 3.009 N/A ARG 248.A NH2 LEU 254.A O no hydrogen 2.888 N/A ARG 248.A NH2 ILE 255.A O no hydrogen 3.016 N/A LYS 249.A N GLU 246.A O no hydrogen 2.990 N/A LYS 249.A NZ GLU 246.A OE1 no hydrogen 2.983 N/A PHE 250.A N MET 247.A O no hydrogen 3.038 N/A ARG 251.A NE GLY 212.A O no hydrogen 2.858 N/A ARG 251.A NH1 ASN 62.A OD1 no hydrogen 3.340 N/A ARG 251.A NH1 SER 64.A OG no hydrogen 2.847 N/A ARG 251.A NH2 ASN 62.A OD1 no hydrogen 2.941 N/A ARG 251.A NH2 ALA 211.A O no hydrogen 2.970 N/A ILE 255.A N ILE 213.A O no hydrogen 2.803 N/A GLN 256.A N GLN 260.A OE1 no hydrogen 2.663 N/A GLN 260.A N THR 257.A OG1 no hydrogen 2.901 N/A GLN 260.A NE2 GLN 256.A OE1 no hydrogen 3.456 N/A LEU 261.A N THR 257.A O no hydrogen 3.006 N/A ARG 262.A N ALA 258.A O no hydrogen 2.856 N/A ARG 262.A NE ASP 5.A OD1 no hydrogen 3.514 N/A ARG 262.A NE ASP 5.A OD2 no hydrogen 2.771 N/A ARG 262.A NH2 ASP 5.A OD2 no hydrogen 3.077 N/A PHE 263.A N ASP 259.A O no hydrogen 2.712 N/A SER 264.A N GLN 260.A O no hydrogen 2.908 N/A SER 264.A OG GLN 260.A O no hydrogen 2.928 N/A TYR 265.A N LEU 261.A O no hydrogen 3.062 N/A LEU 266.A N ARG 262.A O no hydrogen 2.902 N/A ALA 267.A N PHE 263.A O no hydrogen 2.797 N/A VAL 268.A N SER 264.A O no hydrogen 3.048 N/A ILE 269.A N TYR 265.A O no hydrogen 2.869 N/A GLU 270.A N LEU 266.A O no hydrogen 2.588 N/A ALA 272.A N VAL 268.A O no hydrogen 2.831 N/A ALA 272.A N ILE 269.A O no hydrogen 2.934 N/A