Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2cog_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 3.A OG1 PHE 4.A O no hydrogen 2.864 N/A ALA 6.A N GLU 114.A OE2 no hydrogen 2.895 N/A ASP 8.A N LYS 5.A O no hydrogen 2.851 N/A LEU 9.A N ALA 6.A O no hydrogen 2.933 N/A ILE 10.A N PRO 49.A O no hydrogen 2.974 N/A THR 12.A N ILE 51.A O no hydrogen 2.939 N/A ALA 14.A N HIS 34.A NE2 no hydrogen 3.192 N/A LYS 18.A N ASP 33.A OD1 no hydrogen 2.790 N/A LYS 18.A NZ PHE 31.A O no hydrogen 2.847 N/A LYS 18.A NZ THR 32.A O no hydrogen 2.945 N/A ASN 24.A N ASP 22.A OD1 no hydrogen 2.649 N/A THR 29.A N VAL 26.A O no hydrogen 2.994 N/A THR 32.A N LEU 165.A O no hydrogen 2.944 N/A THR 32.A OG1 HIS 34.A O no hydrogen 3.291 N/A THR 32.A OG1 ASP 126.A OD1 no hydrogen 2.931 N/A HIS 34.A N ASP 126.A OD1 no hydrogen 2.861 N/A HIS 34.A ND1 ASP 126.A OD2 no hydrogen 2.730 N/A MET 35.A N LYS 52.A O no hydrogen 2.842 N/A LEU 36.A N VAL 163.A O no hydrogen 3.252 N/A THR 37.A N HIS 50.A O no hydrogen 2.996 N/A VAL 38.A N LEU 161.A O no hydrogen 2.670 N/A TRP 40.A N ALA 159.A O no hydrogen 2.931 N/A SER 41.A N GLY 45.A O no hydrogen 3.207 N/A SER 42.A N THR 157.A O no hydrogen 3.084 N/A PHE 44.A N SER 41.A OG no hydrogen 2.953 N/A GLY 45.A N SER 41.A O no hydrogen 2.620 N/A TRP 46.A NE1 VAL 109.A O no hydrogen 2.988 N/A GLU 47.A N GLU 39.A O no hydrogen 3.004 N/A HIS 50.A N THR 37.A O no hydrogen 2.966 N/A ILE 51.A N ILE 10.A O no hydrogen 3.194 N/A LYS 52.A N MET 35.A O no hydrogen 2.957 N/A LEU 54.A N ASP 33.A O no hydrogen 2.804 N/A GLY 62.A N HIS 60.A ND1 no hydrogen 2.624 N/A SER 63.A N HIS 60.A O no hydrogen 2.906 N/A SER 63.A OG HIS 60.A O no hydrogen 2.495 N/A SER 64.A N GLU 148.A O no hydrogen 3.238 N/A ALA 65.A N GLY 146.A O no hydrogen 3.037 N/A LEU 66.A N SER 63.A O no hydrogen 2.996 N/A HIS 67.A NE2 PRO 61.A O no hydrogen 2.774 N/A TYR 68.A N SER 64.A O no hydrogen 2.863 N/A TYR 68.A OH LEU 151.A O no hydrogen 2.390 N/A VAL 70.A N SER 64.A O no hydrogen 3.450 N/A LEU 72.A N PHE 144.A O no hydrogen 3.072 N/A PHE 73.A N LYS 195.A O no hydrogen 3.084 N/A GLU 74.A N PRO 142.A O no hydrogen 2.964 N/A GLY 75.A N GLU 74.A OE1 no hydrogen 3.243 N/A LEU 76.A N ILE 140.A O no hydrogen 3.073 N/A LYS 77.A NZ THR 306.A O no hydrogen 3.324 N/A ALA 78.A N LEU 138.A O no hydrogen 3.097 N/A PHE 79.A N ARG 87.A O no hydrogen 2.617 N/A ARG 80.A NE VAL 130.A O no hydrogen 3.102 N/A ARG 80.A NE PRO 131.A O no hydrogen 3.125 N/A ARG 80.A NH2 VAL 130.A O no hydrogen 2.852 N/A GLY 81.A N LYS 85.A O no hydrogen 2.750 N/A VAL 82.A N TYR 347.A O no hydrogen 2.926 N/A ASN 84.A N GLY 81.A O no hydrogen 2.546 N/A LYS 85.A N ASP 83.A OD1 no hydrogen 2.681 N/A ARG 87.A N PHE 79.A O no hydrogen 2.632 N/A ARG 87.A NH1 ASP 83.A OD1 no hydrogen 2.959 N/A ARG 87.A NH2 ASP 83.A OD2 no hydrogen 2.423 N/A LEU 88.A N ILE 356.A O no hydrogen 3.078 N/A GLN 90.A N TRP 354.A O no hydrogen 2.646 N/A GLN 90.A NE2 TRP 354.A O no hydrogen 3.662 N/A LEU 93.A N GLN 90.A O no hydrogen 3.079 N/A ASN 94.A ND2 GLN 90.A O no hydrogen 3.358 N/A MET 95.A N PRO 91.A O no hydrogen 3.107 N/A ASP 96.A N ASN 92.A O no hydrogen 3.214 N/A ARG 97.A N LEU 93.A O no hydrogen 2.980 N/A ARG 97.A NE GLU 74.A OE2 no hydrogen 2.708 N/A ARG 97.A NH1 PRO 260.A O no hydrogen 3.093 N/A ARG 97.A NH2 GLU 74.A OE1 no hydrogen 2.752 N/A MET 98.A N ASN 94.A O no hydrogen 2.841 N/A TYR 99.A N MET 95.A O no hydrogen 2.986 N/A ARG 100.A N ASP 96.A O no hydrogen 2.956 N/A SER 101.A N ARG 97.A O no hydrogen 2.840 N/A SER 101.A OG ARG 97.A O no hydrogen 2.988 N/A ALA 102.A N MET 98.A O no hydrogen 2.962 N/A VAL 103.A N TYR 99.A O no hydrogen 3.090 N/A ARG 104.A N ARG 100.A O no hydrogen 3.047 N/A ARG 104.A NH1 GLY 190.A O no hydrogen 3.116 N/A ALA 105.A N ALA 102.A O no hydrogen 3.039 N/A THR 106.A N VAL 103.A O no hydrogen 3.156 N/A THR 106.A OG1 ALA 105.A O no hydrogen 2.510 N/A LEU 107.A N ALA 102.A O no hydrogen 2.786 N/A ASP 111.A N THR 3.A OG1 no hydrogen 2.957 N/A LYS 112.A NZ ASP 96.A OD1 no hydrogen 2.650 N/A GLU 114.A N ASP 111.A OD2 no hydrogen 2.917 N/A LEU 115.A N ASP 111.A O no hydrogen 3.196 N/A LEU 116.A N LYS 112.A O no hydrogen 3.013 N/A GLU 117.A N GLU 113.A O no hydrogen 3.016 N/A CYS 118.A N GLU 114.A O no hydrogen 2.876 N/A CYS 118.A SG GLU 114.A O no hydrogen 3.195 N/A ILE 119.A N LEU 115.A O no hydrogen 2.820 N/A GLN 120.A N LEU 116.A O no hydrogen 2.828 N/A GLN 121.A N GLU 117.A O no hydrogen 2.865 N/A LEU 122.A N CYS 118.A O no hydrogen 2.981 N/A VAL 123.A N ILE 119.A O no hydrogen 2.790 N/A LYS 124.A N GLN 120.A O no hydrogen 2.950 N/A LEU 125.A N GLN 121.A O no hydrogen 3.163 N/A ASP 126.A N LEU 122.A O no hydrogen 3.178 N/A GLN 127.A N LYS 124.A O no hydrogen 3.284 N/A GLN 127.A NE2 LYS 124.A O no hydrogen 3.638 N/A TRP 129.A N ASP 126.A O no hydrogen 2.960 N/A TRP 129.A NE1 ASP 33.A OD2 no hydrogen 2.564 N/A VAL 130.A N GLN 127.A O no hydrogen 3.147 N/A TYR 132.A OH GLU 128.A OE1 no hydrogen 2.708 N/A TYR 132.A OH GLU 128.A OE2 no hydrogen 3.208 N/A SER 135.A N SER 133.A OG no hydrogen 2.945 N/A SER 135.A OG SER 133.A OG no hydrogen 2.852 N/A SER 137.A N VAL 168.A O no hydrogen 2.773 N/A LEU 138.A N ALA 78.A O no hydrogen 3.234 N/A TYR 139.A N SER 166.A O no hydrogen 2.761 N/A ILE 140.A N LEU 76.A O no hydrogen 2.697 N/A ARG 141.A N LEU 164.A O no hydrogen 2.969 N/A ARG 141.A NE GLU 74.A O no hydrogen 2.883 N/A ARG 141.A NH2 TYR 139.A OH no hydrogen 2.843 N/A THR 143.A N PHE 162.A O no hydrogen 2.732 N/A THR 143.A OG1 ARG 141.A O no hydrogen 3.322 N/A PHE 144.A N LEU 72.A O no hydrogen 2.964 N/A ILE 145.A N LEU 160.A O no hydrogen 2.902 N/A GLY 146.A N VAL 70.A O no hydrogen 2.912 N/A THR 147.A N LYS 158.A O no hydrogen 2.924 N/A SER 150.A OG GLU 148.A OE2 no hydrogen 3.454 N/A LYS 158.A NZ THR 147.A O no hydrogen 3.561 N/A ALA 159.A N TRP 40.A O no hydrogen 3.178 N/A LEU 160.A N ILE 145.A O no hydrogen 2.914 N/A LEU 161.A N VAL 38.A O no hydrogen 2.899 N/A PHE 162.A N THR 143.A O no hydrogen 2.768 N/A VAL 163.A N LEU 36.A O no hydrogen 2.856 N/A LEU 164.A N ARG 141.A O no hydrogen 3.157 N/A SER 166.A N TYR 139.A O no hydrogen 3.014 N/A SER 166.A OG VAL 30.A O no hydrogen 2.570 N/A VAL 168.A N SER 137.A O no hydrogen 2.765 N/A VAL 175.A N PRO 312.A O no hydrogen 2.967 N/A SER 176.A N GLN 216.A OE1 no hydrogen 2.520 N/A SER 176.A OG ASP 315.A O no hydrogen 3.476 N/A LEU 177.A N ASP 315.A O no hydrogen 2.612 N/A TRP 178.A N GLN 217.A O no hydrogen 3.040 N/A TRP 178.A NE1 GLU 209.A OE2 no hydrogen 2.695 N/A ALA 179.A N LEU 317.A O no hydrogen 2.877 N/A ASN 180.A ND2 GLU 209.A OE2 no hydrogen 3.105 N/A LYS 182.A N ASN 180.A OD1 no hydrogen 3.015 N/A TYR 183.A N ASN 180.A O no hydrogen 3.242 N/A TYR 183.A OH GLU 209.A OE1 no hydrogen 2.566 N/A ARG 185.A NH2 GLY 192.A O no hydrogen 3.069 N/A ARG 185.A NH2 ILE 257.A O no hydrogen 3.165 N/A GLY 190.A N TRP 187.A O no hydrogen 2.850 N/A THR 191.A OG1 ASN 199.A OD1 no hydrogen 2.690 N/A CYS 194.A N THR 191.A O no hydrogen 2.948 N/A CYS 194.A SG ASP 193.A OD1 no hydrogen 3.831 N/A ASN 199.A N MET 196.A O no hydrogen 3.049 N/A ASN 199.A ND2 THR 191.A O no hydrogen 2.949 N/A TYR 200.A N GLY 197.A O no hydrogen 2.806 N/A GLY 201.A N GLY 197.A O no hydrogen 3.465 N/A SER 203.A N TYR 200.A O no hydrogen 3.012 N/A SER 203.A OG TYR 200.A O no hydrogen 2.785 N/A LEU 204.A N GLY 201.A O no hydrogen 3.483 N/A GLN 207.A N SER 203.A O no hydrogen 2.949 N/A GLN 207.A NE2 GLN 216.A O no hydrogen 3.196 N/A CYS 208.A N LEU 204.A O no hydrogen 2.950 N/A CYS 208.A SG LEU 204.A O no hydrogen 3.269 N/A GLU 209.A N PHE 205.A O no hydrogen 3.013 N/A ALA 210.A N ALA 206.A O no hydrogen 2.891 N/A VAL 211.A N GLN 207.A O no hydrogen 3.064 N/A ASP 212.A N CYS 208.A O no hydrogen 2.879 N/A ASN 213.A N ALA 210.A O no hydrogen 2.899 N/A ASN 213.A ND2 GLU 209.A O no hydrogen 2.801 N/A GLY 214.A N VAL 211.A O no hydrogen 3.361 N/A CYS 215.A N ALA 210.A O no hydrogen 2.989 N/A CYS 215.A SG ASN 213.A O no hydrogen 3.809 N/A GLN 216.A N SER 176.A O no hydrogen 3.106 N/A GLN 216.A NE2 GLY 214.A O no hydrogen 2.882 N/A GLN 217.A N SER 176.A O no hydrogen 3.468 N/A GLN 217.A NE2 GLN 216.A O no hydrogen 2.945 N/A LEU 219.A N TRP 178.A O no hydrogen 2.940 N/A TRP 220.A N GLU 230.A O no hydrogen 3.001 N/A TYR 222.A N GLN 227.A O no hydrogen 2.947 N/A HIS 226.A N GLY 223.A O no hydrogen 2.833 N/A GLN 227.A N TYR 222.A O no hydrogen 2.725 N/A ILE 228.A N LEU 284.A O no hydrogen 2.610 N/A THR 229.A N TRP 220.A O no hydrogen 3.042 N/A THR 229.A OG1 TRP 220.A O no hydrogen 3.048 N/A VAL 231.A N MET 234.A O no hydrogen 2.737 N/A GLY 232.A N VAL 218.A O no hydrogen 2.674 N/A MET 234.A N VAL 231.A O no hydrogen 2.820 N/A ASN 235.A N SER 304.A O no hydrogen 3.072 N/A ASN 235.A ND2 LEU 259.A O no hydrogen 3.395 N/A PHE 237.A N PHE 302.A O no hydrogen 2.936 N/A LEU 238.A N ALA 250.A O no hydrogen 2.858 N/A TYR 239.A N GLU 300.A O no hydrogen 2.785 N/A TYR 239.A OH GLU 247.A OE2 no hydrogen 2.455 N/A TRP 240.A N GLU 248.A O no hydrogen 2.938 N/A TRP 240.A NE1 GLU 248.A OE1 no hydrogen 3.021 N/A ILE 241.A N ARG 297.A O no hydrogen 2.987 N/A ASN 242.A N GLU 246.A O no hydrogen 2.883 N/A GLU 243.A N GLU 243.A OE1 no hydrogen 2.632 N/A GLY 245.A N ASN 242.A O no hydrogen 2.920 N/A GLU 248.A N TRP 240.A O no hydrogen 2.665 N/A LEU 249.A N LYS 278.A O no hydrogen 2.858 N/A ALA 250.A N LEU 238.A O no hydrogen 2.903 N/A THR 251.A N SER 280.A O no hydrogen 3.085 N/A THR 251.A OG1 LEU 236.A O no hydrogen 2.703 N/A ASP 255.A N PRO 253.A O no hydrogen 2.930 N/A LEU 259.A N GLU 230.A OE2 no hydrogen 2.766 N/A ARG 264.A NH2 PRO 252.A O no hydrogen 3.043 N/A ARG 264.A NH2 GLU 281.A OE1 no hydrogen 2.862 N/A ARG 265.A N GLY 261.A O no hydrogen 3.131 N/A ARG 265.A NE ASP 269.A OD1 no hydrogen 3.261 N/A ARG 265.A NH2 ASP 269.A OD1 no hydrogen 3.438 N/A CYS 266.A N VAL 262.A O no hydrogen 3.201 N/A CYS 266.A SG VAL 262.A O no hydrogen 3.185 N/A ILE 267.A N THR 263.A O no hydrogen 2.882 N/A LEU 268.A N ARG 264.A O no hydrogen 3.053 N/A ASP 269.A N ARG 265.A O no hydrogen 2.862 N/A LEU 270.A N CYS 266.A O no hydrogen 2.808 N/A ALA 271.A N ILE 267.A O no hydrogen 2.845 N/A HIS 272.A N LEU 268.A O no hydrogen 2.898 N/A GLN 273.A N ASP 269.A O no hydrogen 2.943 N/A TRP 274.A N LEU 270.A O no hydrogen 3.054 N/A LYS 278.A N GLU 247.A O no hydrogen 3.225 N/A LYS 278.A NZ GLU 246.A OE2 no hydrogen 3.551 N/A SER 280.A N LEU 249.A O no hydrogen 3.049 N/A SER 280.A OG GLU 248.A OE2 no hydrogen 2.955 N/A ARG 282.A NE GLU 248.A OE1 no hydrogen 3.364 N/A ARG 282.A NH1 GLU 243.A OE2 no hydrogen 3.088 N/A ARG 282.A NH2 GLU 243.A OE1 no hydrogen 2.526 N/A ARG 282.A NH2 GLU 248.A OE1 no hydrogen 3.079 N/A TYR 283.A OH ASP 255.A OD1 no hydrogen 2.784 N/A THR 285.A N ASP 288.A OD2 no hydrogen 2.976 N/A ASP 288.A N THR 285.A OG1 no hydrogen 3.024 N/A LEU 289.A N THR 285.A O no hydrogen 3.051 N/A THR 290.A N MET 286.A O no hydrogen 2.630 N/A THR 290.A OG1 MET 286.A O no hydrogen 3.032 N/A THR 290.A OG1 ASP 287.A O no hydrogen 3.075 N/A THR 291.A N ASP 287.A O no hydrogen 2.751 N/A THR 291.A OG1 ASP 287.A O no hydrogen 3.021 N/A ALA 292.A N ASP 288.A O no hydrogen 3.009 N/A LEU 293.A N LEU 289.A O no hydrogen 2.889 N/A GLU 294.A N THR 290.A O no hydrogen 2.993 N/A ASN 296.A N LEU 293.A O no hydrogen 2.813 N/A ASN 296.A ND2 LEU 293.A O no hydrogen 3.421 N/A ARG 297.A N ALA 292.A O no hydrogen 2.940 N/A ARG 297.A NE ILE 241.A O no hydrogen 2.562 N/A ARG 297.A NE ASN 242.A O no hydrogen 3.375 N/A ARG 297.A NH2 ILE 241.A O no hydrogen 3.103 N/A ARG 299.A N TYR 239.A O no hydrogen 3.000 N/A ARG 299.A NH1 ASN 296.A O no hydrogen 3.009 N/A ARG 299.A NH1 VAL 298.A O no hydrogen 3.199 N/A GLU 300.A N TYR 239.A O no hydrogen 3.025 N/A MET 301.A N THR 327.A OG1 no hydrogen 2.922 N/A PHE 302.A N PHE 237.A O no hydrogen 3.092 N/A GLY 303.A N CYS 311.A O no hydrogen 2.751 N/A SER 304.A N ASN 235.A O no hydrogen 2.851 N/A THR 306.A OG1 GLY 75.A O no hydrogen 3.176 N/A CYS 308.A SG VAL 310.A O no hydrogen 3.150 N/A VAL 309.A N GLY 305.A O no hydrogen 2.544 N/A VAL 310.A N CYS 308.A O no hydrogen 2.674 N/A CYS 311.A N GLY 303.A O no hydrogen 2.691 N/A VAL 313.A N MET 301.A O no hydrogen 2.846 N/A SER 314.A N VAL 175.A O no hydrogen 2.912 N/A SER 314.A OG VAL 175.A O no hydrogen 3.376 N/A SER 314.A OG ASP 315.A OD2 no hydrogen 3.267 N/A ILE 316.A N ILE 323.A O no hydrogen 2.812 N/A LEU 317.A N LEU 177.A O no hydrogen 2.605 N/A TYR 318.A N GLU 321.A O no hydrogen 2.950 N/A GLU 321.A N TYR 318.A O no hydrogen 2.947 N/A ILE 323.A N ILE 316.A O no hydrogen 2.747 N/A ILE 325.A N SER 314.A O no hydrogen 2.629 N/A THR 327.A OG1 MET 301.A O no hydrogen 3.358 N/A THR 327.A OG1 VAL 313.A O no hydrogen 2.690 N/A ASN 330.A N PRO 326.A O no hydrogen 3.163 N/A ASN 330.A N THR 327.A O no hydrogen 3.101 N/A ASN 330.A ND2 ARG 299.A O no hydrogen 2.900 N/A LYS 333.A N ASN 330.A O no hydrogen 3.127 N/A LEU 334.A N GLU 300.A OE2 no hydrogen 2.745 N/A ALA 335.A N GLU 300.A OE1 no hydrogen 2.844 N/A SER 336.A N PRO 332.A O no hydrogen 2.930 N/A SER 336.A OG PRO 332.A O no hydrogen 2.600 N/A ARG 337.A N LYS 333.A O no hydrogen 2.931 N/A ARG 337.A NH1 GLU 276.A OE1 no hydrogen 2.666 N/A ARG 337.A NH1 GLU 276.A OE2 no hydrogen 3.177 N/A ARG 337.A NH2 GLU 276.A OE2 no hydrogen 2.571 N/A ILE 338.A N LEU 334.A O no hydrogen 2.740 N/A LEU 339.A N ALA 335.A O no hydrogen 2.975 N/A SER 340.A N SER 336.A O no hydrogen 2.899 N/A SER 340.A OG SER 336.A O no hydrogen 3.324 N/A LYS 341.A N ARG 337.A O no hydrogen 3.078 N/A LYS 341.A NZ GLU 350.A OE1 no hydrogen 3.124 N/A LYS 341.A NZ GLU 350.A OE2 no hydrogen 2.980 N/A LEU 342.A N ILE 338.A O no hydrogen 3.102 N/A THR 343.A N LEU 339.A O no hydrogen 2.828 N/A THR 343.A OG1 LEU 339.A O no hydrogen 2.790 N/A ASP 344.A N SER 340.A O no hydrogen 2.769 N/A ILE 345.A N LYS 341.A O no hydrogen 2.979 N/A GLN 346.A N LEU 342.A O no hydrogen 2.757 N/A TYR 347.A N THR 343.A O no hydrogen 2.939 N/A TYR 347.A OH ALA 136.A O no hydrogen 2.535 N/A GLY 348.A N ILE 345.A O no hydrogen 3.482 N/A ARG 349.A N ASP 344.A O no hydrogen 2.898 N/A ARG 349.A NE ASP 344.A OD2 no hydrogen 2.965 N/A ARG 349.A NH1 THR 134.A OG1 no hydrogen 3.357 N/A ARG 349.A NH2 ASP 344.A OD2 no hydrogen 2.822 N/A GLU 350.A N ASP 344.A O no hydrogen 3.218 N/A ILE 356.A N LEU 88.A O no hydrogen 3.147 N/A