Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2cvo_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 2.A N PRO 29.A O no hydrogen 2.893 N/A VAL 6.A N GLN 30.A O no hydrogen 3.099 N/A ARG 7.A N ASP 73.A OD1 no hydrogen 3.113 N/A ARG 7.A NE ASN 71.A O no hydrogen 2.895 N/A ILE 8.A N ARG 32.A O no hydrogen 2.892 N/A ALA 9.A N ALA 74.A O no hydrogen 2.958 N/A VAL 10.A N VAL 35.A O no hydrogen 2.718 N/A LEU 11.A N PHE 76.A O no hydrogen 2.870 N/A GLY 12.A N THR 37.A O no hydrogen 2.927 N/A GLY 12.A N THR 37.A OG1 no hydrogen 3.068 N/A ALA 13.A N THR 37.A O no hydrogen 2.926 N/A ALA 19.A N GLY 15.A O no hydrogen 3.140 N/A GLU 20.A N TYR 16.A O no hydrogen 2.848 N/A ILE 21.A N THR 17.A O no hydrogen 3.005 N/A VAL 22.A N GLY 18.A O no hydrogen 2.982 N/A ARG 23.A N ALA 19.A O no hydrogen 3.004 N/A ARG 23.A NE GLU 20.A OE1 no hydrogen 2.877 N/A ARG 23.A NH2 GLU 20.A OE2 no hydrogen 2.707 N/A LEU 24.A N GLU 20.A O no hydrogen 2.918 N/A LEU 25.A N ILE 21.A O no hydrogen 2.839 N/A ALA 26.A N VAL 22.A O no hydrogen 3.082 N/A ASN 27.A N LEU 24.A O no hydrogen 2.927 N/A HIS 28.A N LEU 25.A O no hydrogen 2.785 N/A HIS 28.A NE2 ASN 329.A OD1 no hydrogen 2.625 N/A GLN 30.A N HIS 28.A ND1 no hydrogen 3.119 N/A PHE 31.A N HIS 28.A ND1 no hydrogen 2.889 N/A ARG 32.A N VAL 6.A O no hydrogen 3.040 N/A LYS 34.A N ILE 8.A O no hydrogen 2.758 N/A LYS 34.A NZ GLU 5.A OE2 no hydrogen 2.743 N/A VAL 35.A N ILE 8.A O no hydrogen 3.301 N/A THR 37.A N VAL 10.A O no hydrogen 2.967 N/A ALA 38.A N VAL 62.A O no hydrogen 3.373 N/A GLY 43.A N LEU 61.A O no hydrogen 2.669 N/A SER 48.A N GLN 45.A O no hydrogen 2.828 N/A VAL 49.A N GLN 45.A O no hydrogen 3.374 N/A VAL 49.A N PHE 46.A O no hydrogen 3.007 N/A PHE 50.A N PHE 46.A O no hydrogen 2.892 N/A LEU 53.A N PHE 50.A O no hydrogen 2.981 N/A ILE 54.A N PRO 51.A O no hydrogen 3.276 N/A GLN 56.A N LEU 53.A O no hydrogen 3.042 N/A GLN 56.A NE2 THR 55.A OG1 no hydrogen 3.236 N/A LEU 61.A N GLU 44.A O no hydrogen 3.044 N/A VAL 62.A N MET 36.A O no hydrogen 3.159 N/A ASP 66.A N ALA 63.A O no hydrogen 2.752 N/A ALA 67.A N VAL 64.A O no hydrogen 3.051 N/A SER 70.A OG ASP 68.A OD1 no hydrogen 2.600 N/A VAL 72.A N PHE 69.A O no hydrogen 2.761 N/A ASP 73.A N ARG 7.A O no hydrogen 2.845 N/A ALA 74.A N ARG 7.A O no hydrogen 3.200 N/A VAL 75.A N LYS 95.A O no hydrogen 2.797 N/A PHE 76.A N ALA 9.A O no hydrogen 2.799 N/A CYS 77.A N VAL 97.A O no hydrogen 2.964 N/A CYS 77.A SG ASP 98.A OD1 no hydrogen 3.569 N/A GLY 81.A N ASP 102.A OD2 no hydrogen 2.967 N/A GLN 84.A N ASP 102.A OD2 no hydrogen 3.169 N/A GLN 84.A NE2 ASP 102.A O no hydrogen 3.244 N/A ILE 86.A N THR 82.A O no hydrogen 3.150 N/A ILE 87.A N THR 83.A O no hydrogen 2.977 N/A LYS 88.A N GLN 84.A O no hydrogen 3.041 N/A LYS 88.A NZ ARG 120.A O no hydrogen 3.021 N/A GLY 89.A N GLU 85.A O no hydrogen 3.048 N/A GLY 89.A N ILE 86.A O no hydrogen 3.200 N/A LEU 90.A N ILE 87.A O no hydrogen 2.994 N/A GLU 93.A N GLU 93.A OE1 no hydrogen 2.381 N/A LYS 95.A N ASP 73.A O no hydrogen 3.239 N/A LYS 95.A NZ MET 331.A O no hydrogen 3.140 N/A ILE 96.A N ARG 144.A O no hydrogen 2.860 N/A VAL 97.A N VAL 75.A O no hydrogen 2.895 N/A ASP 98.A N VAL 146.A O no hydrogen 2.909 N/A LEU 99.A N CYS 77.A O no hydrogen 2.780 N/A SER 100.A N ASP 98.A OD1 no hydrogen 2.885 N/A SER 100.A OG ASP 98.A OD1 no hydrogen 2.750 N/A SER 100.A OG ASP 98.A OD2 no hydrogen 2.667 N/A ALA 101.A N HIS 80.A NE2 no hydrogen 3.369 N/A ASP 102.A N SER 100.A OG no hydrogen 3.326 N/A ARG 104.A N ALA 101.A O no hydrogen 3.182 N/A ARG 104.A NE SER 100.A O no hydrogen 3.110 N/A ARG 104.A NE ASN 148.A O no hydrogen 2.932 N/A ARG 104.A NH1 GLU 215.A OE1 no hydrogen 2.859 N/A ARG 104.A NH2 LEU 99.A O no hydrogen 2.909 N/A ARG 106.A N GLN 218.A OE1 no hydrogen 3.000 N/A GLU 110.A N ASP 107.A OD1 no hydrogen 2.781 N/A TYR 111.A N ASP 107.A O no hydrogen 3.142 N/A TYR 111.A OH HIS 117.A NE2 no hydrogen 2.934 N/A ALA 112.A N ILE 108.A O no hydrogen 3.335 N/A GLU 113.A N ASN 109.A O no hydrogen 2.827 N/A TRP 114.A N TYR 111.A O no hydrogen 2.895 N/A TYR 115.A N TYR 111.A O no hydrogen 2.796 N/A HIS 117.A ND1 TYR 115.A O no hydrogen 2.833 N/A HIS 119.A NE2 GLN 125.A OE1 no hydrogen 2.977 N/A ARG 120.A N GLN 84.A OE1 no hydrogen 2.471 N/A ALA 121.A N HIS 119.A ND1 no hydrogen 3.006 N/A LEU 124.A N GLU 123.A OE1 no hydrogen 2.868 N/A GLN 125.A N ALA 121.A O no hydrogen 2.883 N/A GLN 125.A NE2 PHE 103.A O no hydrogen 2.985 N/A GLN 125.A NE2 GLN 125.A O no hydrogen 2.886 N/A GLN 126.A N GLU 123.A O no hydrogen 3.274 N/A GLU 127.A N LEU 124.A O no hydrogen 2.780 N/A ALA 128.A N LEU 124.A O no hydrogen 3.266 N/A VAL 129.A N LEU 145.A O no hydrogen 2.917 N/A TYR 130.A OH GLU 215.A OE2 no hydrogen 2.604 N/A GLY 131.A N ALA 147.A O no hydrogen 2.718 N/A LEU 132.A N TYR 130.A O no hydrogen 2.996 N/A THR 133.A OG1 GLN 323.A OE1 no hydrogen 3.469 N/A THR 133.A OG1 ASN 327.A OD1 no hydrogen 2.609 N/A GLU 134.A N GLU 134.A OE1 no hydrogen 2.698 N/A VAL 135.A N LEU 132.A O no hydrogen 2.944 N/A LEU 136.A N LEU 132.A O no hydrogen 2.973 N/A ARG 137.A NE GLU 336.A OE1 no hydrogen 2.498 N/A ARG 137.A NH1 GLU 271.A OE2 no hydrogen 2.817 N/A ARG 137.A NH2 GLU 271.A OE1 no hydrogen 2.874 N/A ARG 137.A NH2 GLU 271.A OE2 no hydrogen 3.454 N/A ARG 137.A NH2 GLU 336.A OE1 no hydrogen 3.340 N/A ARG 137.A NH2 GLU 336.A OE2 no hydrogen 3.051 N/A ILE 140.A N LEU 136.A O no hydrogen 2.936 N/A ARG 141.A N ARG 137.A O no hydrogen 3.026 N/A ASN 142.A N GLU 139.A O no hydrogen 3.212 N/A ALA 143.A N ILE 140.A O no hydrogen 3.035 N/A ARG 144.A NE GLN 92.A O no hydrogen 2.819 N/A ARG 144.A NH2 PRO 91.A O no hydrogen 2.668 N/A VAL 146.A N ILE 96.A O no hydrogen 2.834 N/A ALA 147.A N VAL 129.A O no hydrogen 2.815 N/A ASN 148.A N ASP 98.A O no hydrogen 2.870 N/A ASN 148.A ND2 ALA 320.A O no hydrogen 2.874 N/A GLY 150.A N GLU 215.A OE2 no hydrogen 2.856 N/A TYR 152.A OH TYR 205.A OH no hydrogen 2.800 N/A THR 154.A N GLY 150.A O no hydrogen 3.227 N/A THR 154.A OG1 GLY 150.A O no hydrogen 2.761 N/A SER 155.A N CYS 151.A O no hydrogen 3.198 N/A SER 155.A OG TYR 152.A O no hydrogen 2.755 N/A SER 155.A OG SER 245.A OG no hydrogen 2.722 N/A ILE 156.A N TYR 152.A O no hydrogen 3.155 N/A GLN 157.A N PRO 153.A O no hydrogen 2.942 N/A GLN 157.A NE2 TYR 130.A OH no hydrogen 2.908 N/A GLN 157.A NE2 PRO 153.A O no hydrogen 3.265 N/A LEU 158.A N THR 154.A O no hydrogen 3.435 N/A LEU 160.A N ILE 156.A O no hydrogen 3.094 N/A VAL 161.A N GLN 157.A O no hydrogen 2.827 N/A ILE 164.A N LEU 160.A O no hydrogen 2.868 N/A LYS 165.A N VAL 161.A O no hydrogen 2.929 N/A ALA 166.A N PRO 162.A O no hydrogen 2.946 N/A LYS 167.A N ILE 164.A O no hydrogen 2.834 N/A LEU 168.A N LEU 163.A O no hydrogen 3.007 N/A LYS 170.A N GLU 250.A O no hydrogen 2.787 N/A SER 172.A OG GLU 250.A OE1 no hydrogen 3.018 N/A ASN 173.A ND2 GLU 250.A OE2 no hydrogen 3.405 N/A ILE 175.A N PHE 248.A O no hydrogen 3.123 N/A ILE 176.A N SER 231.A O no hydrogen 2.815 N/A ASP 177.A N THR 246.A O no hydrogen 2.975 N/A ALA 178.A N THR 233.A O no hydrogen 2.979 N/A LYS 179.A N GLN 244.A O no hydrogen 2.681 N/A LYS 179.A NZ ASP 177.A O no hydrogen 3.194 N/A LYS 179.A NZ ASP 177.A OD2 no hydrogen 2.813 N/A LYS 179.A NZ THR 246.A OG1 no hydrogen 3.413 N/A SER 180.A N ASN 235.A O no hydrogen 2.963 N/A SER 180.A OG GLY 181.A O no hydrogen 2.821 N/A GLY 181.A N GLY 242.A O no hydrogen 2.835 N/A VAL 182.A N MET 239.A O no hydrogen 2.872 N/A SER 183.A N LYS 240.A O no hydrogen 2.989 N/A SER 183.A OG LYS 240.A O no hydrogen 2.834 N/A ALA 185.A N VAL 182.A O no hydrogen 2.893 N/A GLY 186.A N SER 183.A O no hydrogen 3.066 N/A ARG 187.A NH1 VAL 49.A O no hydrogen 2.793 N/A ARG 187.A NH2 VAL 49.A O no hydrogen 3.240 N/A ASN 193.A N LYS 190.A O no hydrogen 3.244 N/A LEU 194.A N GLU 191.A O no hydrogen 2.947 N/A GLU 197.A N LEU 194.A O no hydrogen 2.941 N/A ILE 198.A N LEU 194.A O no hydrogen 2.937 N/A ILE 198.A N TYR 195.A O no hydrogen 3.189 N/A ALA 199.A N TYR 195.A O no hydrogen 2.752 N/A TYR 205.A N PRO 234.A O no hydrogen 3.143 N/A TYR 205.A OH TYR 152.A OH no hydrogen 2.800 N/A ARG 211.A NE TRP 114.A O no hydrogen 3.152 N/A HIS 212.A N HIS 210.A ND1 no hydrogen 2.994 N/A VAL 213.A N HIS 210.A O no hydrogen 2.976 N/A ILE 216.A N HIS 212.A O no hydrogen 2.876 N/A GLU 217.A N VAL 213.A O no hydrogen 2.761 N/A GLN 218.A N PRO 214.A O no hydrogen 2.914 N/A GLN 218.A NE2 ARG 104.A O no hydrogen 2.897 N/A GLY 219.A N GLU 215.A O no hydrogen 3.356 N/A LEU 220.A N ILE 216.A O no hydrogen 3.001 N/A SER 221.A N GLU 217.A O no hydrogen 2.720 N/A SER 221.A OG GLU 217.A O no hydrogen 2.947 N/A SER 221.A OG SER 226.A O no hydrogen 3.355 N/A GLU 222.A N GLN 218.A O no hydrogen 3.141 N/A ALA 223.A N GLY 219.A O no hydrogen 3.136 N/A ALA 224.A N LEU 220.A O no hydrogen 2.863 N/A GLU 225.A N SER 221.A O no hydrogen 2.718 N/A SER 226.A N SER 221.A O no hydrogen 3.273 N/A LYS 227.A NZ GLU 217.A OE1 no hydrogen 2.980 N/A LYS 227.A NZ VAL 228.A O no hydrogen 3.373 N/A VAL 228.A N SER 221.A OG no hydrogen 2.756 N/A ILE 230.A N GLU 217.A OE2 no hydrogen 2.872 N/A SER 231.A N ILE 174.A O no hydrogen 3.156 N/A THR 233.A N ILE 176.A O no hydrogen 3.043 N/A LEU 236.A N HIS 203.A O no hydrogen 2.843 N/A ILE 237.A N SER 180.A O no hydrogen 2.879 N/A CYS 238.A SG GLY 201.A O no hydrogen 3.364 N/A MET 239.A N ILE 237.A O no hydrogen 2.911 N/A ARG 241.A NH1 GLU 20.A OE2 no hydrogen 3.041 N/A ARG 241.A NH1 ASP 314.A OD1 no hydrogen 2.793 N/A GLY 242.A N ASN 315.A OD1 no hydrogen 2.814 N/A MET 243.A N ILE 313.A O no hydrogen 2.848 N/A GLN 244.A N LYS 179.A O no hydrogen 2.769 N/A SER 245.A N SER 311.A O no hydrogen 2.840 N/A SER 245.A OG SER 155.A OG no hydrogen 2.722 N/A THR 246.A N ASP 177.A O no hydrogen 2.972 N/A MET 247.A N ILE 309.A O no hydrogen 2.865 N/A PHE 248.A N ILE 175.A O no hydrogen 2.714 N/A VAL 249.A N ALA 307.A O no hydrogen 3.113 N/A MET 251.A N GLY 305.A O no hydrogen 2.784 N/A ALA 252.A N LEU 168.A O no hydrogen 2.871 N/A VAL 255.A N ALA 252.A O no hydrogen 3.008 N/A THR 256.A N ASP 259.A OD1 no hydrogen 3.036 N/A ASP 259.A N THR 256.A OG1 no hydrogen 3.179 N/A LEU 260.A N THR 256.A O no hydrogen 3.238 N/A TYR 261.A N ALA 257.A O no hydrogen 2.872 N/A TYR 261.A OH LEU 277.A O no hydrogen 2.755 N/A GLN 262.A N ASN 258.A O no hydrogen 2.767 N/A HIS 263.A N ASP 259.A O no hydrogen 3.059 N/A LEU 264.A N LEU 260.A O no hydrogen 3.085 N/A LYS 265.A N TYR 261.A O no hydrogen 3.007 N/A SER 266.A N GLN 262.A O no hydrogen 3.066 N/A SER 266.A OG GLN 262.A O no hydrogen 3.268 N/A SER 266.A OG HIS 263.A O no hydrogen 3.058 N/A THR 267.A N HIS 263.A O no hydrogen 2.895 N/A THR 267.A OG1 HIS 263.A O no hydrogen 2.551 N/A TYR 268.A N LEU 264.A O no hydrogen 2.890 N/A TYR 268.A N LYS 265.A O no hydrogen 3.270 N/A TYR 268.A OH LEU 158.A O no hydrogen 2.427 N/A GLU 271.A N TYR 268.A O no hydrogen 2.989 N/A LYS 275.A N CYS 294.A O no hydrogen 2.969 N/A LEU 277.A N MET 296.A O no hydrogen 2.880 N/A SER 281.A N ASN 278.A O no hydrogen 3.046 N/A SER 281.A OG ASN 278.A O no hydrogen 2.937 N/A ARG 286.A NE HIS 284.A ND1 no hydrogen 3.059 N/A HIS 287.A N HIS 284.A O no hydrogen 3.088 N/A VAL 288.A N THR 285.A O no hydrogen 3.163 N/A GLY 290.A N ASP 314.A OD1 no hydrogen 2.639 N/A SER 291.A N VAL 288.A O no hydrogen 2.967 N/A SER 291.A OG VAL 288.A O no hydrogen 2.685 N/A ASN 292.A ND2 GLN 326.A OE1 no hydrogen 3.024 N/A TYR 293.A N SER 291.A OG no hydrogen 3.268 N/A CYS 294.A N PHE 273.A O no hydrogen 3.007 N/A CYS 294.A SG SER 311.A OG no hydrogen 3.243 N/A CYS 294.A SG VAL 312.A O no hydrogen 3.774 N/A PHE 295.A N VAL 312.A O no hydrogen 2.975 N/A MET 296.A N LYS 275.A O no hydrogen 2.958 N/A ASN 297.A N ILE 310.A O no hydrogen 3.063 N/A ASN 297.A ND2 GLY 279.A O no hydrogen 3.079 N/A ASN 297.A ND2 SER 281.A O no hydrogen 2.669 N/A VAL 298.A N ASN 297.A OD1 no hydrogen 2.859 N/A PHE 299.A N ILE 308.A O no hydrogen 2.588 N/A ASP 301.A N ARG 306.A O no hydrogen 3.145 N/A ILE 303.A N ASP 301.A OD2 no hydrogen 2.809 N/A ARG 306.A N ILE 303.A O no hydrogen 3.142 N/A ARG 306.A NH1 PHE 248.A O no hydrogen 2.922 N/A ARG 306.A NH2 ASN 173.A O no hydrogen 3.050 N/A ALA 307.A N VAL 249.A O no hydrogen 2.891 N/A ILE 308.A N PHE 299.A O no hydrogen 2.744 N/A ILE 309.A N MET 247.A O no hydrogen 2.875 N/A ILE 310.A N ASN 297.A O no hydrogen 2.885 N/A SER 311.A N SER 245.A O no hydrogen 3.043 N/A SER 311.A OG SER 155.A O no hydrogen 2.912 N/A VAL 312.A N PHE 295.A O no hydrogen 2.904 N/A ILE 313.A N MET 243.A O no hydrogen 3.081 N/A ASN 315.A ND2 SER 183.A OG no hydrogen 2.741 N/A LEU 316.A N ASP 314.A OD2 no hydrogen 2.880 N/A VAL 317.A N ASP 314.A O no hydrogen 2.931 N/A LYS 318.A NZ GLU 134.A OE1 no hydrogen 2.806 N/A LYS 318.A NZ GLU 134.A OE2 no hydrogen 3.362 N/A LYS 318.A NZ GLN 323.A OE1 no hydrogen 2.716 N/A LYS 318.A NZ GLN 326.A OE1 no hydrogen 2.814 N/A GLY 319.A N ASP 314.A O no hydrogen 3.193 N/A ALA 320.A N VAL 317.A O no hydrogen 2.629 N/A SER 321.A N LEU 316.A O no hydrogen 3.145 N/A SER 321.A OG THR 17.A O no hydrogen 3.159 N/A GLY 322.A N VAL 317.A O no hydrogen 2.729 N/A GLN 323.A N VAL 317.A O no hydrogen 3.230 N/A GLN 323.A NE2 THR 154.A OG1 no hydrogen 3.190 N/A ALA 324.A N ALA 320.A O no hydrogen 3.011 N/A VAL 325.A N SER 321.A O no hydrogen 3.001 N/A GLN 326.A N GLY 322.A O no hydrogen 2.900 N/A GLN 326.A NE2 GLU 134.A OE2 no hydrogen 3.014 N/A GLN 326.A NE2 GLU 336.A OE2 no hydrogen 3.086 N/A ASN 327.A N GLN 323.A O no hydrogen 2.871 N/A ASN 327.A ND2 GLY 131.A O no hydrogen 2.953 N/A ASN 327.A ND2 ASN 148.A OD1 no hydrogen 2.938 N/A LEU 328.A N ALA 324.A O no hydrogen 3.046 N/A ASN 329.A N VAL 325.A O no hydrogen 2.975 N/A ASN 329.A ND2 GLU 336.A O no hydrogen 3.091 N/A ASN 329.A ND2 THR 338.A O no hydrogen 3.194 N/A LEU 330.A N GLN 326.A O no hydrogen 3.265 N/A MET 331.A N ASN 327.A O no hydrogen 2.918 N/A MET 332.A N LEU 328.A O no hydrogen 2.850 N/A MET 332.A N ASN 329.A O no hydrogen 3.112 N/A GLY 333.A N LEU 330.A O no hydrogen 3.252 N/A LEU 334.A N ASN 329.A O no hydrogen 2.798 N/A ASN 337.A ND2 GLU 272.A OE2 no hydrogen 2.736 N/A THR 338.A N PRO 335.A O no hydrogen 3.158 N/A THR 338.A OG1 PRO 335.A O no hydrogen 2.623 N/A LEU 340.A N ASN 337.A O no hydrogen 2.771 N/A GLN 343.A NE2 TYR 293.A OH no hydrogen 3.057 N/A GLN 343.A NE2 GLN 341.A O no hydrogen 3.227 N/A LEU 345.A N VAL 289.A O no hydrogen 2.911 N/A