Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2d0c_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A N GLY 54.A O no hydrogen 2.600 N/A ASN 2.A ND2 ASN 2.A O no hydrogen 2.599 N/A TYR 3.A N PHE 52.A O no hydrogen 2.850 N/A VAL 4.A N SER 69.A O no hydrogen 2.941 N/A ILE 5.A N VAL 50.A O no hydrogen 3.047 N/A GLN 9.A NE2 ASP 13.A OD1 no hydrogen 3.356 N/A GLN 9.A NE2 ASP 13.A OD2 no hydrogen 3.243 N/A LEU 11.A N ASP 8.A OD1 no hydrogen 2.598 N/A LEU 12.A N ASP 8.A O no hydrogen 3.044 N/A ASP 13.A N GLN 9.A O no hydrogen 2.845 N/A ALA 14.A N GLN 10.A O no hydrogen 2.837 N/A LEU 15.A N LEU 11.A O no hydrogen 2.691 N/A ARG 16.A N LEU 12.A O no hydrogen 2.959 N/A ALA 17.A N ASP 13.A O no hydrogen 2.986 N/A HIS 18.A N ALA 14.A O no hydrogen 2.856 N/A TYR 19.A OH GLU 60.A OE2 no hydrogen 2.633 N/A LEU 23.A N ALA 34.A O no hydrogen 2.969 N/A ALA 29.A N HIS 77.A ND1 no hydrogen 3.041 N/A ALA 31.A N PRO 28.A O no hydrogen 2.856 N/A LEU 32.A N ALA 44.A O no hydrogen 2.571 N/A ALA 34.A N LEU 23.A O no hydrogen 3.180 N/A VAL 35.A N ILE 42.A O no hydrogen 3.224 N/A ARG 37.A N VAL 40.A O no hydrogen 2.952 N/A VAL 40.A N ARG 37.A O no hydrogen 2.896 N/A VAL 41.A N GLN 53.A O no hydrogen 2.528 N/A ILE 42.A N VAL 35.A O no hydrogen 3.301 N/A THR 43.A N LEU 51.A O no hydrogen 2.845 N/A ALA 44.A N PHE 33.A O no hydrogen 3.226 N/A TYR 45.A N LYS 49.A O no hydrogen 2.968 N/A TYR 45.A OH ASP 76.A O no hydrogen 3.217 N/A ARG 46.A N GLY 30.A O no hydrogen 3.131 N/A GLY 48.A N TYR 45.A O no hydrogen 2.828 N/A LYS 49.A N SER 47.A OG no hydrogen 3.349 N/A LYS 49.A NZ GLU 73.A OE2 no hydrogen 3.237 N/A LYS 49.A NZ GLN 78.A OE1 no hydrogen 2.680 N/A VAL 50.A N ILE 5.A O no hydrogen 2.731 N/A LEU 51.A N THR 43.A O no hydrogen 2.631 N/A PHE 52.A N TYR 3.A O no hydrogen 2.705 N/A GLN 53.A N VAL 41.A O no hydrogen 3.014 N/A GLY 54.A N SER 1.A O no hydrogen 3.390 N/A ALA 56.A N ASP 39.A O no hydrogen 2.772 N/A GLU 60.A N ALA 56.A O no hydrogen 3.197 N/A ALA 61.A N ALA 57.A O no hydrogen 2.861 N/A ALA 62.A N GLU 58.A O no hydrogen 3.002 N/A LYS 63.A N GLU 60.A O no hydrogen 3.154 N/A TRP 64.A N ALA 61.A O no hydrogen 2.979 N/A ILE 65.A N ALA 61.A O no hydrogen 3.339 N/A SER 71.A N ASN 2.A O no hydrogen 3.108 N/A ASP 76.A N THR 74.A O no hydrogen 2.544 N/A GLN 78.A N ALA 29.A O no hydrogen 3.154 N/A GLN 78.A NE2 ASP 76.A O no hydrogen 2.878 N/A ALA 81.A N GLN 78.A O no hydrogen 2.936 N/A LEU 82.A N PRO 79.A O no hydrogen 3.478 N/A HIS 85.A N ALA 81.A O no hydrogen 3.166 N/A GLN 86.A N ALA 83.A O no hydrogen 2.861 N/A GLN 86.A NE2 HIS 85.A ND1 no hydrogen 3.353 N/A LEU 87.A N ALA 83.A O no hydrogen 2.670 N/A GLY 88.A N ALA 84.A O no hydrogen 2.895 N/A LEU 90.A N LEU 87.A O no hydrogen 2.912 N/A SER 91.A N GLU 196.A OE1 no hydrogen 2.753 N/A SER 91.A OG GLU 196.A OE1 no hydrogen 2.781 N/A ALA 92.A N VAL 114.A O no hydrogen 3.167 N/A ILE 93.A N ALA 197.A O no hydrogen 3.015 N/A GLY 94.A N ALA 112.A O no hydrogen 2.847 N/A SER 95.A N ILE 199.A O no hydrogen 2.972 N/A ASP 96.A N ALA 110.A O no hydrogen 2.996 N/A GLU 97.A N ASP 96.A OD1 no hydrogen 2.846 N/A VAL 98.A N VAL 108.A O no hydrogen 2.944 N/A ASP 102.A N GLY 99.A O no hydrogen 3.029 N/A TYR 103.A N GLY 266.A O no hydrogen 2.964 N/A TYR 103.A OH THR 298.A OG1 no hydrogen 2.750 N/A GLY 105.A N CYS 290.A O no hydrogen 2.973 N/A ILE 107.A N LEU 156.A O no hydrogen 3.390 N/A VAL 108.A N VAL 98.A O no hydrogen 3.015 N/A VAL 109.A N THR 154.A O no hydrogen 2.977 N/A ALA 110.A N ASP 96.A O no hydrogen 2.852 N/A ALA 111.A N ALA 152.A O no hydrogen 3.019 N/A ALA 112.A N GLY 94.A O no hydrogen 2.948 N/A TYR 113.A N PRO 150.A O no hydrogen 3.058 N/A VAL 114.A N ALA 92.A O no hydrogen 2.801 N/A ARG 116.A N ASP 115.A OD1 no hydrogen 2.724 N/A ARG 116.A NE GLU 196.A OE1 no hydrogen 3.072 N/A ARG 116.A NE GLU 196.A OE2 no hydrogen 3.444 N/A ARG 116.A NH2 GLU 196.A OE2 no hydrogen 3.114 N/A HIS 118.A N ASP 115.A O no hydrogen 2.844 N/A ILE 119.A N ASP 115.A O no hydrogen 3.249 N/A ILE 119.A N ARG 116.A O no hydrogen 3.312 N/A ILE 122.A N HIS 118.A O no hydrogen 2.975 N/A ALA 123.A N ILE 119.A O no hydrogen 2.821 N/A ALA 124.A N ALA 120.A O no hydrogen 2.610 N/A LEU 125.A N ILE 122.A O no hydrogen 3.073 N/A GLY 126.A N ALA 123.A O no hydrogen 2.845 N/A SER 130.A N VAL 127.A O no hydrogen 3.261 N/A LYS 131.A NZ LYS 128.A O no hydrogen 2.696 N/A ILE 138.A N ASN 134.A O no hydrogen 3.308 N/A LYS 139.A N ASP 135.A O no hydrogen 3.064 N/A LYS 139.A NZ GLU 253.A OE2 no hydrogen 3.220 N/A ARG 140.A N ALA 137.A O no hydrogen 2.965 N/A ILE 141.A N ALA 137.A O no hydrogen 2.807 N/A ALA 142.A N ILE 138.A O no hydrogen 2.995 N/A ALA 144.A N ILE 141.A O no hydrogen 3.072 N/A ILE 145.A N ILE 141.A O no hydrogen 3.199 N/A ILE 145.A N ALA 142.A O no hydrogen 2.980 N/A MET 146.A N ALA 142.A O no hydrogen 3.003 N/A THR 148.A N ILE 145.A O no hydrogen 2.809 N/A THR 148.A OG1 ALA 144.A O no hydrogen 2.478 N/A VAL 149.A N ILE 145.A O no hydrogen 2.947 N/A ALA 152.A N ALA 111.A O no hydrogen 3.041 N/A THR 154.A N VAL 109.A O no hydrogen 2.903 N/A THR 154.A OG1 THR 182.A OG1 no hydrogen 2.626 N/A LEU 156.A N ILE 107.A O no hydrogen 2.938 N/A TYR 161.A N ASP 157.A O no hydrogen 2.820 N/A TYR 161.A OH GLN 171.A OE1 no hydrogen 2.897 N/A ASN 162.A N ASN 158.A O no hydrogen 2.743 N/A ASN 162.A ND2 GLU 288.A O no hydrogen 3.089 N/A ASN 162.A ND2 ALA 291.A O no hydrogen 2.754 N/A ARG 163.A N PRO 159.A O no hydrogen 3.045 N/A TRP 164.A N GLN 160.A O no hydrogen 3.029 N/A GLN 165.A N TYR 161.A O no hydrogen 2.926 N/A ARG 166.A N ASN 162.A O no hydrogen 3.017 N/A ARG 166.A NH2 GLU 288.A OE1 no hydrogen 2.620 N/A SER 167.A N TRP 164.A O no hydrogen 2.964 N/A SER 167.A OG ARG 163.A O no hydrogen 2.709 N/A GLY 168.A N GLN 165.A O no hydrogen 3.312 N/A MET 169.A N TRP 164.A O no hydrogen 3.037 N/A THR 172.A OG1 TYR 212.A OH no hydrogen 3.187 N/A MET 174.A N PRO 170.A O no hydrogen 2.993 N/A LYS 175.A N GLN 171.A O no hydrogen 2.859 N/A ALA 176.A N THR 172.A O no hydrogen 3.242 N/A LEU 177.A N LYS 173.A O no hydrogen 3.191 N/A LEU 178.A N MET 174.A O no hydrogen 2.870 N/A HIS 179.A N LYS 175.A O no hydrogen 2.766 N/A ASN 180.A N ALA 176.A O no hydrogen 2.940 N/A ARG 181.A N LEU 177.A O no hydrogen 2.869 N/A ARG 181.A NE GLU 216.A OE2 no hydrogen 3.178 N/A ARG 181.A NH2 GLU 216.A OE1 no hydrogen 3.329 N/A THR 182.A N LEU 178.A O no hydrogen 3.085 N/A THR 182.A OG1 THR 154.A OG1 no hydrogen 2.626 N/A THR 182.A OG1 LEU 178.A O no hydrogen 2.817 N/A LEU 183.A N HIS 179.A O no hydrogen 2.986 N/A VAL 184.A N ASN 180.A O no hydrogen 3.048 N/A LYS 185.A N ARG 181.A O no hydrogen 3.263 N/A LYS 185.A NZ VAL 153.A O no hydrogen 2.893 N/A LEU 186.A N THR 182.A O no hydrogen 3.079 N/A VAL 187.A N LEU 183.A O no hydrogen 2.833 N/A ASP 188.A N VAL 184.A O no hydrogen 3.132 N/A ALA 189.A N LYS 185.A O no hydrogen 2.975 N/A ILE 190.A N LEU 186.A O no hydrogen 2.966 N/A ALA 191.A N ASP 188.A O no hydrogen 3.145 N/A GLU 196.A N SER 91.A O no hydrogen 2.921 N/A ILE 198.A N ARG 223.A O no hydrogen 3.131 N/A ILE 199.A N ILE 93.A O no hydrogen 2.670 N/A ILE 200.A N HIS 225.A O no hydrogen 2.795 N/A ASP 201.A N SER 95.A O no hydrogen 3.193 N/A GLU 202.A N LEU 227.A O no hydrogen 2.677 N/A LYS 205.A NZ SER 208.A OG no hydrogen 3.262 N/A ARG 206.A NH1 VAL 224.A O no hydrogen 3.217 N/A TYR 209.A N LYS 205.A O no hydrogen 2.974 N/A PHE 210.A N ARG 206.A O no hydrogen 3.362 N/A ARG 211.A N ASP 207.A O no hydrogen 3.292 N/A TYR 212.A N SER 208.A O no hydrogen 2.929 N/A TYR 212.A N TYR 209.A O no hydrogen 3.133 N/A TYR 212.A OH THR 172.A OG1 no hydrogen 3.187 N/A LEU 213.A N PHE 210.A O no hydrogen 3.195 N/A SER 214.A OG ARG 211.A O no hydrogen 2.659 N/A GLU 216.A N LEU 213.A O no hydrogen 3.052 N/A ARG 218.A NH1 ASP 188.A OD1 no hydrogen 3.026 N/A ARG 218.A NH2 ASP 188.A OD1 no hydrogen 2.957 N/A ARG 223.A NH2 GLU 194.A OE1 no hydrogen 2.902 N/A VAL 224.A N ARG 221.A O no hydrogen 3.349 N/A HIS 225.A N ILE 198.A O no hydrogen 2.612 N/A LEU 227.A N ILE 200.A O no hydrogen 3.125 N/A ALA 230.A N ASP 201.A OD1 no hydrogen 3.019 N/A SER 232.A N LYS 229.A O no hydrogen 3.141 N/A SER 232.A OG LYS 229.A O no hydrogen 2.722 N/A VAL 233.A N ALA 230.A O no hydrogen 2.739 N/A HIS 234.A N ALA 230.A O no hydrogen 3.208 N/A HIS 234.A NE2 LEU 90.A O no hydrogen 2.679 N/A SER 236.A N HIS 234.A ND1 no hydrogen 2.978 N/A SER 236.A OG HIS 234.A ND1 no hydrogen 3.224 N/A VAL 237.A N HIS 234.A O no hydrogen 3.271 N/A ALA 239.A N VAL 235.A O no hydrogen 3.007 N/A ALA 240.A N SER 236.A O no hydrogen 2.967 N/A SER 241.A N VAL 237.A O no hydrogen 2.888 N/A ILE 242.A N ALA 238.A O no hydrogen 3.050 N/A ILE 243.A N ALA 239.A O no hydrogen 3.011 N/A ALA 244.A N ALA 240.A O no hydrogen 2.765 N/A ARG 245.A N SER 241.A O no hydrogen 2.927 N/A ARG 245.A NH1 SER 130.A O no hydrogen 3.093 N/A ARG 245.A NH1 LEU 133.A O no hydrogen 2.770 N/A ARG 245.A NH2 LEU 133.A O no hydrogen 2.766 N/A ARG 245.A NH2 ASP 135.A OD1 no hydrogen 3.493 N/A TYR 246.A N ILE 242.A O no hydrogen 2.947 N/A VAL 247.A N ILE 243.A O no hydrogen 2.962 N/A PHE 248.A N ALA 244.A O no hydrogen 3.007 N/A LEU 249.A N ARG 245.A O no hydrogen 3.107 N/A GLU 250.A N TYR 246.A O no hydrogen 2.922 N/A GLU 251.A N VAL 247.A O no hydrogen 2.812 N/A MET 252.A N PHE 248.A O no hydrogen 2.862 N/A GLU 253.A N LEU 249.A O no hydrogen 3.089 N/A GLN 254.A N GLU 250.A O no hydrogen 3.141 N/A LEU 255.A N GLU 251.A O no hydrogen 2.810 N/A SER 256.A N MET 252.A O no hydrogen 2.709 N/A SER 256.A OG MET 252.A O no hydrogen 2.922 N/A ARG 257.A N GLU 253.A O no hydrogen 2.988 N/A ALA 258.A N GLN 254.A O no hydrogen 3.016 N/A VAL 259.A N LEU 255.A O no hydrogen 2.857 N/A GLY 260.A N SER 256.A O no hydrogen 2.693 N/A LEU 261.A N SER 256.A O no hydrogen 2.986 N/A LEU 263.A N SER 256.A OG no hydrogen 3.110 N/A LYS 265.A NZ ASP 135.A OD2 no hydrogen 3.168 N/A GLY 266.A N ASP 102.A OD1 no hydrogen 2.743 N/A VAL 271.A N GLY 268.A O no hydrogen 2.926 N/A GLU 273.A N ALA 269.A O no hydrogen 2.951 N/A ALA 274.A N ILE 270.A O no hydrogen 2.800 N/A ALA 275.A N VAL 271.A O no hydrogen 2.936 N/A ALA 276.A N ASP 272.A O no hydrogen 2.837 N/A ARG 277.A N GLU 273.A O no hydrogen 2.927 N/A ILE 278.A N ALA 274.A O no hydrogen 3.022 N/A ILE 279.A N ALA 275.A O no hydrogen 2.875 N/A ARG 280.A N ALA 276.A O no hydrogen 3.044 N/A ARG 280.A NH2 ILE 304.A O no hydrogen 3.248 N/A ALA 281.A N ARG 277.A O no hydrogen 2.965 N/A ARG 282.A N ILE 278.A O no hydrogen 2.685 N/A ARG 282.A NE VAL 259.A O no hydrogen 3.462 N/A ARG 282.A NH1 ALA 258.A O no hydrogen 3.263 N/A GLY 283.A N ILE 279.A O no hydrogen 3.038 N/A MET 286.A N GLY 283.A O no hydrogen 3.308 N/A LEU 287.A N GLU 284.A O no hydrogen 3.011 N/A GLU 288.A N GLU 285.A O no hydrogen 3.069 N/A THR 289.A N MET 286.A O no hydrogen 2.933 N/A THR 289.A OG1 MET 286.A O no hydrogen 2.845 N/A CYS 290.A N LEU 287.A O no hydrogen 3.186 N/A CYS 290.A SG MET 286.A O no hydrogen 3.754 N/A ALA 291.A N LEU 287.A O no hydrogen 2.885 N/A LYS 292.A N TYR 103.A O no hydrogen 2.925 N/A LYS 292.A NZ GLY 99.A O no hydrogen 3.086 N/A LYS 292.A NZ ASP 102.A O no hydrogen 2.771 N/A LYS 292.A NZ GLY 105.A O no hydrogen 2.597 N/A LYS 292.A NZ PRO 106.A O no hydrogen 3.559 N/A LEU 293.A N ASN 162.A OD1 no hydrogen 2.824 N/A PHE 295.A N LYS 292.A O no hydrogen 3.141 N/A THR 298.A OG1 TYR 103.A OH no hydrogen 2.750 N/A THR 298.A OG1 LEU 293.A O no hydrogen 2.608 N/A LYS 300.A N ALA 296.A O no hydrogen 3.456 N/A ALA 301.A N ASN 297.A O no hydrogen 2.831 N/A LEU 302.A N THR 298.A O no hydrogen 2.991 N/A ALA 303.A N LYS 299.A O no hydrogen 3.068 N/A ALA 303.A N LYS 300.A O no hydrogen 2.949 N/A ILE 304.A N LYS 300.A O no hydrogen 2.869 N/A ALA 305.A N ALA 301.A O no hydrogen 2.786 N/A LYS 306.A N LEU 302.A O no hydrogen 3.108 N/A ARG 307.A N ALA 303.A O no hydrogen 2.938 N/A