Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2e3d_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 2.A OG1 ASP 152.A OD1 no hydrogen 2.536 N/A LYS 3.A NZ GLU 121.A OE1 no hydrogen 3.264 N/A VAL 4.A N THR 2.A OG1 no hydrogen 2.738 N/A LYS 5.A NZ THR 2.A O no hydrogen 2.886 N/A LYS 6.A NZ GLU 52.A OE1 no hydrogen 2.776 N/A ALA 7.A N GLU 52.A O no hydrogen 2.992 N/A VAL 8.A N ALA 124.A O no hydrogen 2.746 N/A ILE 9.A N VAL 54.A O no hydrogen 2.655 N/A VAL 11.A N VAL 56.A O no hydrogen 2.843 N/A THR 16.A N LEU 14.A O no hydrogen 3.293 N/A MET 18.A N GLY 15.A O no hydrogen 2.762 N/A LEU 19.A N THR 16.A O no hydrogen 3.288 N/A THR 22.A OG1 GLY 15.A O no hydrogen 3.228 N/A LYS 23.A N PRO 20.A O no hydrogen 2.822 N/A MET 29.A N PRO 26.A O no hydrogen 2.981 N/A LEU 30.A N LYS 27.A O no hydrogen 3.267 N/A LEU 32.A N LYS 35.A O no hydrogen 2.947 N/A LEU 37.A N LEU 30.A O no hydrogen 2.733 N/A ILE 38.A N GLU 28.A O no hydrogen 3.002 N/A GLN 39.A N PRO 36.A O no hydrogen 2.856 N/A TYR 40.A N LEU 37.A O no hydrogen 3.153 N/A TYR 40.A OH LEU 32.A O no hydrogen 2.795 N/A VAL 41.A N LEU 37.A O no hydrogen 3.381 N/A VAL 42.A N ILE 38.A O no hydrogen 3.043 N/A ASN 43.A N GLN 39.A O no hydrogen 2.696 N/A GLU 44.A N TYR 40.A O no hydrogen 2.870 N/A CYS 45.A N VAL 41.A O no hydrogen 3.104 N/A CYS 45.A N VAL 42.A O no hydrogen 3.075 N/A CYS 45.A SG VAL 41.A O no hydrogen 3.280 N/A ILE 46.A N VAL 42.A O no hydrogen 3.013 N/A ALA 47.A N ASN 43.A O no hydrogen 2.946 N/A ALA 48.A N GLU 44.A O no hydrogen 3.143 N/A ALA 48.A N CYS 45.A O no hydrogen 3.120 N/A GLY 49.A N ILE 46.A O no hydrogen 2.750 N/A ILE 50.A N CYS 45.A O no hydrogen 2.965 N/A ILE 53.A N THR 95.A O no hydrogen 2.897 N/A VAL 54.A N ALA 7.A O no hydrogen 2.685 N/A LEU 55.A N MET 97.A O no hydrogen 2.902 N/A VAL 56.A N ILE 9.A O no hydrogen 2.869 N/A THR 57.A N VAL 99.A O no hydrogen 2.786 N/A THR 57.A OG1 HIS 58.A O no hydrogen 3.116 N/A HIS 58.A N THR 57.A OG1 no hydrogen 2.363 N/A HIS 58.A ND1 SER 60.A OG no hydrogen 2.945 N/A SER 60.A OG HIS 58.A ND1 no hydrogen 2.945 N/A LYS 61.A N HIS 58.A O no hydrogen 3.185 N/A LYS 61.A NZ VAL 11.A O no hydrogen 2.998 N/A LYS 61.A NZ GLY 13.A O no hydrogen 2.963 N/A LYS 61.A NZ GLU 28.A OE1 no hydrogen 2.931 N/A ILE 64.A N LYS 61.A O no hydrogen 2.968 N/A ASN 66.A N ASN 62.A O no hydrogen 2.664 N/A HIS 67.A N SER 63.A O no hydrogen 2.901 N/A HIS 67.A N ILE 64.A O no hydrogen 3.241 N/A HIS 67.A NE2 GLN 39.A OE1 no hydrogen 2.882 N/A PHE 68.A N GLU 65.A O no hydrogen 3.257 N/A ASP 69.A N GLU 65.A O no hydrogen 3.200 N/A LEU 74.A N SER 71.A O no hydrogen 2.416 N/A GLU 75.A N SER 71.A O no hydrogen 2.865 N/A ALA 76.A N PHE 72.A O no hydrogen 2.930 N/A MET 77.A N GLU 73.A O no hydrogen 3.065 N/A LEU 78.A N GLU 75.A O no hydrogen 2.723 N/A GLU 79.A N GLU 75.A O no hydrogen 2.857 N/A GLU 79.A N ALA 76.A O no hydrogen 3.043 N/A ASP 84.A N ARG 80.A O no hydrogen 3.423 N/A GLU 85.A N GLN 81.A O no hydrogen 2.891 N/A VAL 86.A N LEU 82.A O no hydrogen 2.848 N/A GLN 87.A N LEU 83.A O no hydrogen 3.082 N/A GLN 87.A NE2 GLU 75.A OE2 no hydrogen 3.041 N/A SER 88.A N ASP 84.A O no hydrogen 2.852 N/A SER 88.A OG ASP 84.A O no hydrogen 2.812 N/A CYS 90.A SG PRO 91.A O no hydrogen 3.912 N/A CYS 90.A SG VAL 94.A O no hydrogen 3.311 N/A VAL 94.A N PRO 91.A O no hydrogen 2.583 N/A THR 95.A N THR 51.A O no hydrogen 2.920 N/A MET 97.A N ILE 53.A O no hydrogen 2.831 N/A VAL 99.A N LEU 55.A O no hydrogen 3.128 N/A GLN 101.A N THR 57.A O no hydrogen 2.882 N/A HIS 109.A ND1 GLN 101.A OE1 no hydrogen 2.973 N/A ALA 110.A N GLY 106.A O no hydrogen 2.677 N/A VAL 111.A N LEU 107.A O no hydrogen 2.811 N/A LEU 112.A N GLY 108.A O no hydrogen 2.972 N/A CYS 113.A N HIS 109.A O no hydrogen 3.029 N/A CYS 113.A SG HIS 109.A O no hydrogen 3.349 N/A ALA 114.A N VAL 111.A O no hydrogen 2.775 N/A HIS 115.A N LEU 112.A O no hydrogen 2.812 N/A HIS 115.A NE2 ASP 120.A OD1 no hydrogen 2.805 N/A VAL 118.A N ALA 114.A O no hydrogen 2.947 N/A GLY 119.A N HIS 115.A O no hydrogen 2.791 N/A VAL 123.A N LEU 212.A O no hydrogen 2.781 N/A ALA 124.A N LYS 6.A O no hydrogen 3.063 N/A VAL 125.A N TYR 210.A O no hydrogen 2.711 N/A ILE 126.A N VAL 8.A O no hydrogen 3.105 N/A LEU 127.A N GLY 208.A O no hydrogen 3.190 N/A VAL 130.A N LEU 127.A O no hydrogen 3.370 N/A ILE 131.A N HIS 252.A O no hydrogen 2.750 N/A ASP 133.A N LYS 250.A O no hydrogen 2.773 N/A TYR 135.A N ASP 133.A OD1 no hydrogen 2.769 N/A GLU 136.A N ASP 133.A O no hydrogen 3.018 N/A GLU 136.A N ASP 133.A OD1 no hydrogen 3.280 N/A SER 137.A OG LYS 248.A O no hydrogen 3.151 N/A ASP 138.A N ASP 142.A OD2 no hydrogen 2.886 N/A SER 140.A N ASP 138.A OD1 no hydrogen 2.805 N/A SER 140.A OG ASP 138.A OD1 no hydrogen 2.711 N/A SER 140.A OG ASP 138.A OD2 no hydrogen 3.447 N/A GLN 141.A N ASP 138.A O no hydrogen 2.905 N/A ASP 142.A N ASP 138.A O no hydrogen 2.695 N/A ASN 143.A N TYR 245.A OH no hydrogen 2.925 N/A ASN 143.A ND2 LYS 248.A O no hydrogen 2.814 N/A MET 147.A N ASN 143.A O no hydrogen 2.721 N/A ILE 148.A N LEU 144.A O no hydrogen 2.817 N/A ARG 149.A N ALA 145.A O no hydrogen 3.015 N/A ARG 150.A N GLU 146.A O no hydrogen 2.846 N/A ARG 150.A NE GLU 243.A OE1 no hydrogen 2.751 N/A ARG 150.A NH2 GLU 243.A OE1 no hydrogen 3.171 N/A ARG 150.A NH2 GLU 243.A OE2 no hydrogen 2.510 N/A PHE 151.A N MET 147.A O no hydrogen 3.161 N/A ASP 152.A N ILE 148.A O no hydrogen 2.990 N/A GLU 153.A N ARG 149.A O no hydrogen 2.961 N/A THR 154.A N ARG 150.A O no hydrogen 2.967 N/A THR 154.A OG1 ARG 150.A O no hydrogen 2.728 N/A GLY 155.A N PHE 151.A O no hydrogen 2.552 N/A HIS 156.A N THR 154.A OG1 no hydrogen 2.836 N/A GLN 158.A N VAL 211.A O no hydrogen 2.782 N/A GLN 158.A NE2 HIS 156.A O no hydrogen 2.926 N/A GLN 158.A NE2 GLU 243.A OE1 no hydrogen 2.909 N/A ILE 159.A N GLU 243.A O no hydrogen 2.883 N/A MET 160.A N ARG 209.A O no hydrogen 2.909 N/A VAL 161.A N TYR 245.A O no hydrogen 2.957 N/A GLU 162.A N ALA 205.A O no hydrogen 2.765 N/A VAL 164.A N ASN 203.A O no hydrogen 2.799 N/A THR 168.A N ASP 166.A OD1 no hydrogen 3.138 N/A THR 168.A OG1 ASP 166.A OD1 no hydrogen 2.889 N/A THR 168.A OG1 ASP 166.A OD2 no hydrogen 3.547 N/A ALA 169.A N ASP 166.A O no hydrogen 3.354 N/A TYR 170.A N VAL 167.A O no hydrogen 3.139 N/A VAL 172.A N VAL 192.A O no hydrogen 2.817 N/A VAL 173.A N LEU 204.A O no hydrogen 3.177 N/A ASP 174.A N GLY 190.A O no hydrogen 3.075 N/A CYS 175.A SG VAL 186.A O no hydrogen 4.046 N/A CYS 175.A SG PRO 187.A O no hydrogen 3.698 N/A LYS 176.A N ASP 174.A OD1 no hydrogen 2.660 N/A VAL 178.A N CYS 175.A O no hydrogen 3.124 N/A ALA 181.A N GLU 184.A OE2 no hydrogen 2.788 N/A GLY 183.A N HIS 246.A O no hydrogen 2.730 N/A GLU 184.A N ALA 181.A O no hydrogen 2.869 N/A SER 185.A OG GLN 158.A OE1 no hydrogen 2.541 N/A VAL 186.A N ALA 244.A O no hydrogen 2.881 N/A MET 188.A N VAL 242.A O no hydrogen 2.752 N/A VAL 189.A N ASP 174.A O no hydrogen 2.780 N/A VAL 192.A N VAL 172.A O no hydrogen 2.776 N/A LYS 194.A N TYR 170.A O no hydrogen 2.381 N/A VAL 199.A N LYS 196.A O no hydrogen 3.035 N/A SER 202.A OG VAL 173.A O no hydrogen 2.502 N/A ASN 203.A ND2 VAL 164.A O no hydrogen 3.264 N/A LEU 204.A N SER 202.A OG no hydrogen 3.176 N/A ALA 205.A N GLU 162.A O no hydrogen 2.896 N/A ILE 206.A N GLY 171.A O no hydrogen 2.931 N/A VAL 207.A N MET 160.A O no hydrogen 2.836 N/A ARG 209.A NE GLU 44.A OE1 no hydrogen 2.873 N/A ARG 209.A NE GLU 44.A OE2 no hydrogen 3.326 N/A ARG 209.A NH1 LEU 127.A O no hydrogen 2.921 N/A ARG 209.A NH1 GLY 208.A O no hydrogen 3.212 N/A ARG 209.A NH2 GLU 44.A OE2 no hydrogen 2.657 N/A ARG 209.A NH2 VAL 130.A O no hydrogen 2.944 N/A TYR 210.A N VAL 125.A O no hydrogen 2.888 N/A VAL 211.A N GLN 158.A O no hydrogen 3.080 N/A LEU 212.A N VAL 123.A O no hydrogen 2.696 N/A SER 213.A N SER 157.A OG no hydrogen 2.980 N/A SER 213.A OG GLU 240.A OE1 no hydrogen 3.294 N/A ASP 215.A N SER 213.A OG no hydrogen 2.879 N/A ILE 216.A N SER 213.A O no hydrogen 3.116 N/A TRP 217.A N ALA 214.A O no hydrogen 3.285 N/A TRP 217.A NE1 GLU 121.A O no hydrogen 2.791 N/A LEU 220.A N ILE 216.A O no hydrogen 2.872 N/A ALA 221.A N TRP 217.A O no hydrogen 3.327 N/A GLN 228.A NE2 GLU 193.A OE1 no hydrogen 3.122 N/A ALA 232.A N GLN 228.A O no hydrogen 3.052 N/A ILE 233.A N LEU 229.A O no hydrogen 2.830 N/A ASP 234.A N THR 230.A O no hydrogen 2.726 N/A MET 235.A N ASP 231.A O no hydrogen 3.037 N/A LEU 236.A N ALA 232.A O no hydrogen 2.913 N/A ILE 237.A N ILE 233.A O no hydrogen 2.993 N/A GLU 238.A N ASP 234.A O no hydrogen 3.383 N/A GLU 240.A N LEU 236.A O no hydrogen 2.745 N/A GLU 240.A N ILE 237.A O no hydrogen 3.304 N/A GLU 243.A N SER 157.A O no hydrogen 3.023 N/A ALA 244.A N VAL 186.A O no hydrogen 2.785 N/A TYR 245.A N ILE 159.A O no hydrogen 2.837 N/A TYR 245.A OH GLU 146.A OE1 no hydrogen 2.379 N/A HIS 246.A N GLU 184.A O no hydrogen 2.876 N/A HIS 246.A ND1 MET 247.A O no hydrogen 3.106 N/A MET 247.A N VAL 161.A O no hydrogen 3.043 N/A LYS 248.A N ASN 143.A OD1 no hydrogen 2.709 N/A SER 251.A OG GLU 162.A OE2 no hydrogen 2.760 N/A HIS 252.A N ILE 131.A O no hydrogen 2.816 N/A HIS 252.A NE2 ASP 133.A OD2 no hydrogen 2.801 N/A CYS 254.A N ASP 129.A O no hydrogen 2.807 N/A GLY 255.A N ASP 253.A OD1 no hydrogen 3.037 N/A LYS 257.A NZ LEU 19.A O no hydrogen 3.015 N/A GLY 259.A N ASN 256.A OD1 no hydrogen 3.266 N/A TYR 260.A N ASN 256.A O no hydrogen 2.915 N/A TYR 260.A OH PRO 31.A O no hydrogen 2.552 N/A MET 261.A N LYS 257.A O no hydrogen 2.895 N/A GLN 262.A N LEU 258.A O no hydrogen 2.878 N/A ALA 263.A N GLY 259.A O no hydrogen 2.987 N/A PHE 264.A N TYR 260.A O no hydrogen 2.760 N/A VAL 265.A N MET 261.A O no hydrogen 3.140 N/A GLU 266.A N GLN 262.A O no hydrogen 2.915 N/A TYR 267.A N ALA 263.A O no hydrogen 2.777 N/A GLY 268.A N PHE 264.A O no hydrogen 2.852 N/A ILE 269.A N VAL 265.A O no hydrogen 2.975 N/A ARG 270.A N GLU 266.A O no hydrogen 3.369 N/A ARG 270.A NH1 ASP 133.A OD2 no hydrogen 3.293 N/A ARG 270.A NH2 ASP 133.A OD2 no hydrogen 2.639 N/A HIS 271.A N GLY 268.A O no hydrogen 3.231 N/A HIS 271.A NE2 ASP 34.A OD2 no hydrogen 2.932 N/A THR 273.A N ASN 272.A OD1 no hydrogen 2.875 N/A LEU 274.A N HIS 271.A ND1 no hydrogen 2.884 N/A GLY 275.A N HIS 271.A O no hydrogen 3.121 N/A PHE 278.A N LEU 274.A O no hydrogen 2.779 N/A LYS 279.A N GLY 275.A O no hydrogen 2.708 N/A ALA 280.A N THR 276.A O no hydrogen 2.973 N/A TRP 281.A N GLU 277.A O no hydrogen 2.783 N/A LEU 282.A N PHE 278.A O no hydrogen 2.835 N/A GLU 283.A N LYS 279.A O no hydrogen 2.879 N/A GLU 283.A N ALA 280.A O no hydrogen 2.694 N/A GLU 284.A N ALA 280.A O no hydrogen 3.152 N/A GLU 285.A N TRP 281.A O no hydrogen 3.033 N/A MET 286.A N GLU 283.A O no hydrogen 3.054 N/A