Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2e7i_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 3.A N LYS 305.A O no hydrogen 2.697 N/A ASN 4.A ND2 ASP 6.A O no hydrogen 3.475 N/A ILE 5.A N HIS 307.A O no hydrogen 3.276 N/A GLN 9.A N ASP 6.A O no hydrogen 3.230 N/A THR 10.A N ASP 6.A O no hydrogen 3.164 N/A THR 10.A OG1 ASP 6.A O no hydrogen 3.482 N/A THR 10.A OG1 PRO 7.A O no hydrogen 3.369 N/A THR 10.A OG1 SER 320.A OG no hydrogen 2.473 N/A LYS 13.A NZ THR 10.A O no hydrogen 3.108 N/A ARG 19.A N THR 15.A O no hydrogen 2.620 N/A GLN 20.A N GLU 16.A O no hydrogen 2.811 N/A ALA 21.A N GLU 17.A O no hydrogen 2.785 N/A LEU 22.A N ALA 18.A O no hydrogen 3.109 N/A LEU 22.A N ARG 19.A O no hydrogen 3.059 N/A LEU 23.A N GLN 20.A O no hydrogen 2.619 N/A GLU 24.A N GLN 20.A O no hydrogen 3.403 N/A GLU 24.A N GLU 24.A OE1 no hydrogen 2.614 N/A TRP 25.A N LEU 22.A O no hydrogen 3.290 N/A PHE 31.A N PRO 27.A O no hydrogen 2.644 N/A ILE 32.A N ILE 28.A O no hydrogen 3.090 N/A HIS 33.A N HIS 29.A O no hydrogen 2.839 N/A ASN 34.A N PHE 31.A O no hydrogen 3.369 N/A ASN 34.A ND2 ASP 30.A O no hydrogen 3.250 N/A ASN 34.A ND2 ASP 30.A OD2 no hydrogen 3.015 N/A GLN 35.A N ASP 30.A O no hydrogen 3.236 N/A LEU 36.A N PHE 31.A O no hydrogen 2.773 N/A LYS 38.A N ASN 34.A O no hydrogen 3.082 N/A PHE 39.A N GLN 35.A O no hydrogen 2.817 N/A LEU 40.A N LEU 36.A O no hydrogen 2.976 N/A GLY 41.A N LYS 38.A O no hydrogen 2.921 N/A CYS 42.A N PRO 37.A O no hydrogen 3.075 N/A CYS 42.A SG PRO 37.A O no hydrogen 3.926 N/A CYS 42.A SG VAL 44.A O no hydrogen 3.473 N/A VAL 44.A N MET 195.A O no hydrogen 3.059 N/A ARG 46.A N MET 193.A O no hydrogen 2.830 N/A ARG 46.A NE GLU 214.A OE1 no hydrogen 3.313 N/A ARG 46.A NE GLU 214.A OE2 no hydrogen 3.083 N/A ARG 46.A NH1 ALA 45.A O no hydrogen 2.745 N/A ARG 46.A NH2 GLU 214.A OE2 no hydrogen 3.557 N/A THR 48.A N GLY 191.A O no hydrogen 2.674 N/A THR 48.A OG1 GLY 50.A O no hydrogen 2.550 N/A GLY 50.A N THR 48.A OG1 no hydrogen 3.201 N/A ARG 52.A NH2 TYR 77.A OH no hydrogen 3.545 N/A ALA 54.A N GLY 50.A O no hydrogen 3.113 N/A LYS 55.A N ALA 51.A O no hydrogen 2.649 N/A LYS 55.A NZ SER 78.A OG no hydrogen 2.528 N/A LYS 55.A NZ SER 79.A OG no hydrogen 2.716 N/A LYS 55.A NZ ASN 156.A OD1 no hydrogen 3.557 N/A PHE 56.A N ARG 52.A O no hydrogen 3.006 N/A ALA 57.A N GLU 53.A O no hydrogen 3.207 N/A VAL 58.A N ALA 54.A O no hydrogen 3.284 N/A MET 59.A N LYS 55.A O no hydrogen 3.254 N/A HIS 60.A N PHE 56.A O no hydrogen 2.696 N/A SER 61.A N ALA 57.A O no hydrogen 2.848 N/A SER 61.A OG ILE 202.A O no hydrogen 3.310 N/A SER 61.A OG GLU 216.A OE1 no hydrogen 3.059 N/A LEU 62.A N MET 59.A O no hydrogen 2.972 N/A ALA 63.A N MET 59.A O no hydrogen 2.849 N/A ALA 67.A N LYS 64.A O no hydrogen 2.567 N/A TRP 68.A N GLU 120.A O no hydrogen 2.625 N/A VAL 69.A N ASN 89.A O no hydrogen 3.057 N/A VAL 70.A N LEU 123.A O no hydrogen 3.012 N/A MET 71.A N ALA 91.A O no hydrogen 3.129 N/A ASP 72.A N LEU 125.A O no hydrogen 3.359 N/A GLU 73.A N VAL 93.A O no hydrogen 3.012 N/A ASN 74.A ND2 TYR 101.A O no hydrogen 3.464 N/A CYS 75.A N ASP 72.A O no hydrogen 2.613 N/A CYS 75.A SG HIS 76.A O no hydrogen 3.463 N/A SER 78.A N HIS 76.A ND1 no hydrogen 2.805 N/A SER 78.A OG HIS 76.A ND1 no hydrogen 2.645 N/A VAL 81.A N TYR 77.A O no hydrogen 2.834 N/A ALA 82.A N SER 78.A O no hydrogen 2.909 N/A ALA 83.A N TYR 80.A O no hydrogen 2.923 N/A GLU 84.A N TYR 80.A O no hydrogen 3.084 N/A ARG 85.A N VAL 81.A O no hydrogen 2.840 N/A ALA 86.A N ALA 83.A O no hydrogen 2.812 N/A GLY 87.A N GLU 84.A O no hydrogen 2.761 N/A LEU 88.A N ALA 83.A O no hydrogen 3.208 N/A ASN 89.A N ALA 67.A O no hydrogen 3.127 N/A ALA 91.A N VAL 69.A O no hydrogen 2.937 N/A VAL 93.A N MET 71.A O no hydrogen 3.153 N/A LYS 95.A N GLU 73.A OE1 no hydrogen 3.123 N/A LYS 95.A NZ TYR 133.A OH no hydrogen 3.020 N/A THR 96.A N ALA 102.A O no hydrogen 2.891 N/A THR 96.A OG1 ALA 102.A O no hydrogen 2.987 N/A TYR 98.A N ASP 97.A OD1 no hydrogen 2.917 N/A ASP 100.A N ASP 97.A O no hydrogen 3.211 N/A ASN 107.A N THR 104.A OG1 no hydrogen 3.030 N/A PHE 108.A N THR 104.A O no hydrogen 3.174 N/A ALA 109.A N PRO 105.A O no hydrogen 3.074 N/A GLN 110.A N GLU 106.A O no hydrogen 2.973 N/A GLN 110.A NE2 GLU 106.A O no hydrogen 3.398 N/A THR 111.A N ASN 107.A O no hydrogen 2.699 N/A THR 111.A OG1 ASN 107.A O no hydrogen 2.753 N/A ILE 112.A N PHE 108.A O no hydrogen 2.708 N/A GLU 113.A N ALA 109.A O no hydrogen 2.955 N/A GLU 114.A N GLN 110.A O no hydrogen 2.497 N/A THR 115.A N THR 111.A O no hydrogen 2.837 N/A THR 115.A OG1 THR 111.A O no hydrogen 3.005 N/A LYS 116.A N ILE 112.A O no hydrogen 3.244 N/A LYS 116.A NZ TYR 149.A O no hydrogen 2.565 N/A LYS 117.A N GLU 114.A O no hydrogen 3.281 N/A ARG 118.A N THR 115.A O no hydrogen 2.356 N/A GLY 119.A N LYS 116.A O no hydrogen 3.030 N/A VAL 122.A N TRP 68.A O no hydrogen 2.961 N/A ALA 124.A N PRO 152.A O no hydrogen 2.777 N/A LEU 125.A N VAL 70.A O no hydrogen 2.705 N/A ILE 126.A N LEU 154.A O no hydrogen 3.227 N/A THR 127.A N ASP 72.A OD1 no hydrogen 2.993 N/A THR 127.A OG1 ASP 72.A OD1 no hydrogen 3.030 N/A THR 127.A OG1 ASP 72.A OD2 no hydrogen 2.577 N/A THR 127.A OG1 ASN 74.A O no hydrogen 3.509 N/A TYR 128.A N ASN 156.A O no hydrogen 3.221 N/A ASP 130.A N ASN 135.A O no hydrogen 3.244 N/A ASN 132.A N ASP 130.A OD1 no hydrogen 2.880 N/A TYR 133.A N ASP 130.A OD1 no hydrogen 2.583 N/A GLY 134.A N ASP 130.A O no hydrogen 3.263 N/A GLY 134.A N ASP 130.A OD1 no hydrogen 3.303 N/A ASN 135.A ND2 ASP 100.A O no hydrogen 3.085 N/A LEU 136.A N ASP 268.A OD1 no hydrogen 2.908 N/A LYS 141.A N ASP 138.A O no hydrogen 2.732 N/A LYS 141.A N ASP 138.A OD1 no hydrogen 2.956 N/A ILE 142.A N ASP 138.A O no hydrogen 2.709 N/A ALA 143.A N VAL 139.A O no hydrogen 2.350 N/A LYS 144.A N LYS 141.A O no hydrogen 2.824 N/A VAL 145.A N LYS 141.A O no hydrogen 2.875 N/A CYS 146.A N ILE 142.A O no hydrogen 2.860 N/A CYS 146.A SG ILE 142.A O no hydrogen 3.471 N/A SER 147.A N ALA 143.A O no hydrogen 3.165 N/A SER 147.A OG ALA 143.A O no hydrogen 3.138 N/A GLU 148.A N LYS 144.A O no hydrogen 2.951 N/A TYR 149.A N CYS 146.A O no hydrogen 3.139 N/A ASP 150.A N SER 147.A O no hydrogen 3.409 N/A VAL 151.A N CYS 146.A O no hydrogen 3.242 N/A LEU 153.A N ASP 174.A OD1 no hydrogen 3.473 N/A LEU 154.A N ALA 124.A O no hydrogen 2.785 N/A VAL 155.A N PHE 175.A O no hydrogen 3.379 N/A ASN 156.A N ILE 126.A O no hydrogen 2.996 N/A ALA 160.A N GLY 157.A O no hydrogen 2.783 N/A ILE 161.A N GLY 157.A O no hydrogen 3.031 N/A ARG 163.A N ALA 160.A O no hydrogen 3.071 N/A ARG 163.A NH1 PRO 7.A O no hydrogen 3.347 N/A MET 164.A N ALA 160.A O no hydrogen 2.868 N/A LEU 168.A N LEU 40.A O no hydrogen 2.940 N/A LYS 169.A N GLY 41.A O no hydrogen 3.033 N/A GLU 170.A N SER 167.A OG no hydrogen 3.226 N/A ILE 171.A N SER 167.A O no hydrogen 2.877 N/A GLY 172.A N LEU 168.A O no hydrogen 2.802 N/A PHE 175.A N LEU 153.A O no hydrogen 2.741 N/A VAL 177.A N VAL 155.A O no hydrogen 2.873 N/A GLY 178.A N VAL 192.A O no hydrogen 2.809 N/A GLY 180.A N ILE 190.A O no hydrogen 3.240 N/A SER 183.A N SER 179.A O no hydrogen 3.214 N/A SER 183.A OG ALA 158.A O no hydrogen 2.936 N/A ALA 185.A N GLY 11.A O no hydrogen 3.271 N/A ALA 186.A N GLY 180.A O no hydrogen 2.760 N/A SER 187.A N THR 229.A OG1 no hydrogen 3.202 N/A SER 187.A OG THR 229.A OG1 no hydrogen 3.135 N/A GLY 191.A N THR 48.A O no hydrogen 2.707 N/A VAL 192.A N GLY 178.A O no hydrogen 2.935 N/A MET 193.A N ARG 46.A O no hydrogen 2.863 N/A GLY 194.A N ILE 176.A O no hydrogen 2.714 N/A MET 195.A N VAL 44.A O no hydrogen 2.811 N/A LYS 196.A N ASP 174.A O no hydrogen 3.298 N/A LYS 196.A NZ ASP 174.A OD2 no hydrogen 3.409 N/A GLU 197.A N ASP 43.A OD1 no hydrogen 3.078 N/A TRP 199.A N LYS 196.A O no hydrogen 2.976 N/A TRP 199.A NE1 ASP 174.A OD2 no hydrogen 2.944 N/A ALA 200.A N GLU 197.A O no hydrogen 2.589 N/A GLU 201.A N GLU 201.A OE2 no hydrogen 2.652 N/A VAL 203.A N TRP 199.A O no hydrogen 3.207 N/A LEU 204.A N ALA 200.A O no hydrogen 2.568 N/A ARG 205.A NH1 GLU 216.A OE1 no hydrogen 2.636 N/A ARG 205.A NH2 ILE 202.A O no hydrogen 2.930 N/A ARG 205.A NH2 GLU 216.A OE1 no hydrogen 2.626 N/A SER 207.A N LYS 213.A O no hydrogen 3.297 N/A LYS 211.A N LYS 209.A O no hydrogen 3.170 N/A LYS 213.A N TYR 210.A O no hydrogen 3.001 N/A VAL 215.A N ARG 205.A O no hydrogen 2.855 N/A LEU 217.A N GLU 214.A O no hydrogen 3.014 N/A LEU 218.A N VAL 215.A O no hydrogen 3.100 N/A GLY 219.A N GLU 214.A O no hydrogen 3.159 N/A ILE 228.A N GLY 224.A O no hydrogen 3.203 N/A THR 229.A N ALA 225.A O no hydrogen 3.057 N/A THR 229.A OG1 SER 187.A OG no hydrogen 3.135 N/A THR 229.A OG1 ALA 225.A O no hydrogen 3.041 N/A THR 229.A OG1 THR 226.A O no hydrogen 2.531 N/A LEU 230.A N THR 226.A O no hydrogen 2.973 N/A MET 231.A N ILE 227.A O no hydrogen 2.587 N/A ALA 232.A N ILE 228.A O no hydrogen 2.946 N/A SER 233.A N THR 229.A O no hydrogen 2.911 N/A SER 233.A OG ALA 185.A O no hydrogen 2.922 N/A SER 233.A OG THR 229.A O no hydrogen 3.208 N/A PHE 234.A N LEU 230.A O no hydrogen 2.972 N/A VAL 237.A N SER 233.A O no hydrogen 3.033 N/A ARG 238.A N PHE 234.A O no hydrogen 2.775 N/A GLU 239.A N PRO 235.A O no hydrogen 3.293 N/A GLU 239.A N HIS 236.A O no hydrogen 3.035 N/A ARG 240.A N HIS 236.A O no hydrogen 2.722 N/A ARG 240.A NH1 GLY 11.A O no hydrogen 3.062 N/A ARG 240.A NH1 GLY 162.A O no hydrogen 3.144 N/A ARG 240.A NH2 GLY 11.A O no hydrogen 3.217 N/A ILE 241.A N VAL 237.A O no hydrogen 3.356 N/A LYS 242.A N GLU 239.A O no hydrogen 3.003 N/A LYS 242.A NZ GLU 239.A OE1 no hydrogen 2.912 N/A LYS 242.A NZ GLU 239.A OE2 no hydrogen 3.552 N/A ARG 243.A N ARG 240.A O no hydrogen 2.978 N/A ARG 243.A NE GLU 247.A OE2 no hydrogen 3.224 N/A TRP 244.A N ILE 241.A O no hydrogen 3.372 N/A GLU 246.A N ARG 243.A O no hydrogen 2.763 N/A GLU 247.A N ARG 243.A O no hydrogen 3.186 N/A VAL 248.A N TRP 244.A O no hydrogen 2.903 N/A GLU 249.A N ASP 245.A O no hydrogen 2.950 N/A LYS 250.A N GLU 246.A O no hydrogen 2.660 N/A LYS 250.A NZ TYR 322.A O no hydrogen 3.257 N/A LYS 250.A NZ LEU 324.A O no hydrogen 2.570 N/A ALA 251.A N GLU 247.A O no hydrogen 2.997 N/A ARG 252.A N VAL 248.A O no hydrogen 2.928 N/A ARG 253.A N GLU 249.A O no hydrogen 2.933 N/A ARG 253.A NH2 ASP 326.A OD1 no hydrogen 2.907 N/A PHE 254.A N LYS 250.A O no hydrogen 2.907 N/A ALA 255.A N ALA 251.A O no hydrogen 3.059 N/A ALA 256.A N ARG 252.A O no hydrogen 3.125 N/A GLU 257.A N ARG 253.A O no hydrogen 2.890 N/A MET 258.A N PHE 254.A O no hydrogen 3.060 N/A GLU 259.A N ALA 255.A O no hydrogen 2.925 N/A LYS 260.A N ALA 256.A O no hydrogen 3.051 N/A LEU 261.A N GLU 257.A O no hydrogen 3.071 N/A GLY 262.A N GLU 259.A O no hydrogen 2.857 N/A ILE 263.A N MET 258.A O no hydrogen 3.149 N/A LYS 264.A N HIS 279.A O no hydrogen 2.677 N/A LYS 264.A NZ GLU 259.A OE1 no hydrogen 3.242 N/A GLN 265.A NE2 GLN 265.A O no hydrogen 3.463 N/A GLN 265.A NE2 ASP 268.A O no hydrogen 2.820 N/A LEU 266.A N PHE 277.A O no hydrogen 2.985 N/A GLY 267.A N PRO 99.A O no hydrogen 2.612 N/A HIS 271.A ND1 ASP 268.A O no hydrogen 2.705 N/A MET 276.A N LEU 319.A O no hydrogen 2.942 N/A PHE 278.A N PHE 317.A O no hydrogen 2.707 N/A HIS 279.A N LYS 264.A O no hydrogen 2.577 N/A ALA 280.A N ARG 315.A O no hydrogen 2.811 N/A TYR 284.A N ALA 280.A O no hydrogen 3.214 N/A TYR 284.A N GLU 281.A O no hydrogen 2.870 N/A GLU 285.A N GLU 281.A O no hydrogen 2.962 N/A ILE 286.A N VAL 282.A O no hydrogen 2.998 N/A SER 287.A N LEU 283.A O no hydrogen 3.130 N/A SER 287.A OG LEU 283.A O no hydrogen 3.490 N/A SER 287.A OG TYR 284.A O no hydrogen 2.249 N/A LYS 288.A N GLU 285.A O no hydrogen 2.733 N/A LYS 289.A N ILE 286.A O no hydrogen 2.628 N/A ALA 290.A N ILE 286.A O no hydrogen 2.626 N/A GLY 293.A N ALA 290.A O no hydrogen 3.168 N/A PHE 296.A N GLY 293.A O no hydrogen 2.583 N/A ARG 299.A N PHE 295.A O no hydrogen 2.988 N/A GLU 300.A N PHE 296.A O no hydrogen 2.838 N/A LEU 301.A N LEU 297.A O no hydrogen 2.921 N/A LYS 302.A N TYR 298.A O no hydrogen 2.671 N/A SER 303.A OG ARG 299.A O no hydrogen 3.418 N/A SER 303.A OG GLU 300.A O no hydrogen 2.722 N/A ARG 304.A N LEU 301.A O no hydrogen 2.542 N/A ARG 304.A NE GLU 300.A OE1 no hydrogen 3.219 N/A ARG 304.A NH1 GLU 300.A OE1 no hydrogen 3.114 N/A ARG 304.A NH2 GLU 338.A OE1 no hydrogen 3.104 N/A ILE 306.A N LEU 301.A O no hydrogen 3.122 N/A HIS 307.A N ILE 3.A O no hydrogen 3.491 N/A LEU 313.A N LYS 310.A O no hydrogen 3.164 N/A ARG 315.A NE GLU 281.A OE2 no hydrogen 3.178 N/A ARG 315.A NH2 GLU 281.A OE2 no hydrogen 3.447 N/A PHE 317.A N PHE 278.A O no hydrogen 3.258 N/A LYS 318.A NZ GLY 131.A O no hydrogen 3.531 N/A LEU 319.A N MET 276.A O no hydrogen 2.810 N/A SER 320.A N ILE 5.A O no hydrogen 2.700 N/A SER 320.A OG THR 10.A OG1 no hydrogen 2.473 N/A SER 320.A OG ASP 274.A OD2 no hydrogen 2.365 N/A THR 321.A N ASP 274.A O no hydrogen 3.144 N/A TYR 322.A N SER 320.A OG no hydrogen 3.088 N/A SER 325.A N GLU 328.A OE1 no hydrogen 2.565 N/A SER 325.A OG GLU 328.A OE1 no hydrogen 3.031 N/A VAL 329.A N SER 325.A O no hydrogen 2.839 N/A ASP 330.A N ASP 326.A O no hydrogen 2.789 N/A TYR 331.A N GLU 327.A O no hydrogen 2.709 N/A TYR 331.A OH ARG 304.A O no hydrogen 2.587 N/A VAL 332.A N GLU 328.A O no hydrogen 3.032 N/A LEU 333.A N VAL 329.A O no hydrogen 2.917 N/A ASN 334.A N ASP 330.A O no hydrogen 2.801 N/A ALA 335.A N TYR 331.A O no hydrogen 2.819 N/A PHE 336.A N VAL 332.A O no hydrogen 3.187 N/A LYS 337.A N LEU 333.A O no hydrogen 3.083 N/A LYS 337.A NZ ASN 334.A OD1 no hydrogen 2.637 N/A GLU 338.A N ASN 334.A O no hydrogen 2.895 N/A ILE 339.A N ALA 335.A O no hydrogen 3.160 N/A ILE 340.A N PHE 336.A O no hydrogen 2.927 N/A ILE 340.A N LYS 337.A O no hydrogen 3.150 N/A GLU 341.A N LYS 337.A O no hydrogen 3.128 N/A LYS 342.A N GLU 338.A O no hydrogen 2.768 N/A LYS 342.A NZ GLU 300.A OE2 no hydrogen 2.613 N/A TYR 343.A N ILE 339.A O no hydrogen 3.535 N/A SER 344.A OG TYR 343.A O no hydrogen 2.424 N/A