Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2ef5_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 3.A N THR 36.A O no hydrogen 3.081 N/A ALA 4.A N PHE 72.A O no hydrogen 2.818 N/A VAL 5.A N GLU 38.A O no hydrogen 2.899 N/A VAL 6.A N ILE 74.A O no hydrogen 3.031 N/A GLY 7.A N GLY 41.A O no hydrogen 2.922 N/A VAL 8.A N LEU 76.A O no hydrogen 2.745 N/A MET 10.A N VAL 8.A O no hydrogen 2.681 N/A LEU 12.A N ASP 79.A OD2 no hydrogen 2.601 N/A MET 16.A N GLY 13.A O no hydrogen 3.039 N/A GLY 17.A N VAL 14.A O no hydrogen 2.846 N/A ALA 20.A N MET 16.A O no hydrogen 3.143 N/A LEU 21.A N GLY 17.A O no hydrogen 2.898 N/A ARG 22.A N PRO 18.A O no hydrogen 2.972 N/A ARG 22.A NE ASP 39.A OD2 no hydrogen 2.847 N/A ARG 22.A NH1 ASP 42.A OD1 no hydrogen 2.854 N/A ARG 22.A NH2 ASP 39.A OD1 no hydrogen 3.012 N/A ARG 22.A NH2 GLY 41.A O no hydrogen 2.999 N/A ARG 22.A NH2 ASP 42.A OD1 no hydrogen 2.995 N/A TYR 23.A N SER 19.A O no hydrogen 2.784 N/A ALA 24.A N ALA 20.A O no hydrogen 3.006 N/A ALA 24.A N LEU 21.A O no hydrogen 3.133 N/A ARG 25.A N ARG 22.A O no hydrogen 2.836 N/A GLU 28.A N GLU 28.A OE1 no hydrogen 2.513 N/A GLN 29.A N ARG 25.A O no hydrogen 3.063 N/A GLN 29.A NE2 ALA 24.A O no hydrogen 3.044 N/A GLN 29.A NE2 ARG 25.A O no hydrogen 3.428 N/A LEU 30.A N LEU 26.A O no hydrogen 2.994 N/A GLU 31.A N LEU 27.A O no hydrogen 3.129 N/A ASP 32.A N GLU 28.A O no hydrogen 3.025 N/A LEU 33.A N GLN 29.A O no hydrogen 3.147 N/A LEU 33.A N LEU 30.A O no hydrogen 3.162 N/A GLY 34.A N GLU 31.A O no hydrogen 2.753 N/A TYR 35.A N LEU 30.A O no hydrogen 3.211 N/A TYR 35.A OH LEU 268.A O no hydrogen 2.576 N/A THR 36.A N GLU 1.A O no hydrogen 2.905 N/A THR 36.A OG1 GLU 1.A O no hydrogen 3.218 N/A GLU 38.A N VAL 3.A O no hydrogen 2.991 N/A LEU 40.A N VAL 5.A O no hydrogen 2.751 N/A GLY 41.A N ASP 39.A OD1 no hydrogen 2.760 N/A VAL 43.A N GLY 7.A O no hydrogen 2.866 N/A LEU 50.A N LEU 47.A O no hydrogen 3.283 N/A GLU 52.A N GLU 52.A OE1 no hydrogen 2.613 N/A ILE 53.A N TYR 49.A O no hydrogen 2.845 N/A ARG 54.A N LEU 50.A O no hydrogen 2.819 N/A ARG 54.A NE ARG 132.A O no hydrogen 2.742 N/A ARG 54.A NH2 GLU 135.A OE2 no hydrogen 2.823 N/A ALA 55.A N GLU 51.A O no hydrogen 2.938 N/A ALA 56.A N GLU 52.A O no hydrogen 3.111 N/A ALA 57.A N ILE 53.A O no hydrogen 2.882 N/A LEU 58.A N ARG 54.A O no hydrogen 2.877 N/A VAL 59.A N ALA 55.A O no hydrogen 3.123 N/A LEU 60.A N ALA 56.A O no hydrogen 3.015 N/A LYS 61.A N ALA 57.A O no hydrogen 2.840 N/A LYS 61.A NZ VAL 136.A O no hydrogen 2.803 N/A GLU 62.A N LEU 58.A O no hydrogen 3.021 N/A ARG 63.A N VAL 59.A O no hydrogen 2.939 N/A LEU 64.A N LEU 60.A O no hydrogen 2.996 N/A ALA 65.A N LYS 61.A O no hydrogen 2.918 N/A ALA 66.A N GLU 62.A O no hydrogen 3.080 N/A LEU 67.A N LEU 64.A O no hydrogen 3.099 N/A VAL 71.A N PRO 68.A O no hydrogen 3.359 N/A PHE 72.A N ARG 2.A O no hydrogen 2.882 N/A ILE 74.A N ALA 4.A O no hydrogen 2.859 N/A VAL 75.A N LEU 241.A O no hydrogen 2.871 N/A LEU 76.A N VAL 6.A O no hydrogen 2.817 N/A GLY 77.A N LEU 243.A O no hydrogen 2.893 N/A ASP 79.A N MET 10.A O no hydrogen 2.752 N/A HIS 80.A N GLU 245.A OE2 no hydrogen 2.915 N/A HIS 80.A NE2 SER 198.A OG no hydrogen 2.710 N/A LEU 82.A N ASP 79.A O no hydrogen 3.240 N/A SER 83.A N HIS 80.A O no hydrogen 2.931 N/A SER 83.A OG HIS 80.A O no hydrogen 3.420 N/A SER 83.A OG SER 198.A OG no hydrogen 3.165 N/A SER 83.A OG ASP 242.A OD2 no hydrogen 2.914 N/A MET 84.A N SER 81.A O no hydrogen 3.061 N/A GLY 85.A N LEU 82.A O no hydrogen 2.995 N/A SER 86.A N LEU 82.A O no hydrogen 2.977 N/A SER 86.A OG SER 83.A O no hydrogen 3.380 N/A SER 86.A OG ASP 242.A OD1 no hydrogen 2.875 N/A SER 86.A OG ASP 242.A OD2 no hydrogen 3.082 N/A VAL 87.A N SER 83.A O no hydrogen 2.949 N/A GLY 89.A N GLY 85.A O no hydrogen 2.882 N/A ALA 90.A N SER 86.A O no hydrogen 2.761 N/A ALA 91.A N VAL 87.A O no hydrogen 2.873 N/A ARG 92.A N GLY 89.A O no hydrogen 3.347 N/A ARG 92.A NH1 ALA 65.A O no hydrogen 2.438 N/A ARG 92.A NH2 ALA 65.A O no hydrogen 3.184 N/A ARG 94.A N ALA 91.A O no hydrogen 3.018 N/A ARG 95.A NE ASP 144.A OD2 no hydrogen 2.863 N/A ARG 95.A NH2 ASP 144.A OD1 no hydrogen 2.774 N/A ARG 95.A NH2 ASP 144.A OD2 no hydrogen 3.472 N/A GLY 97.A N PRO 194.A O no hydrogen 2.887 N/A VAL 98.A N ASP 144.A O no hydrogen 2.823 N/A VAL 99.A N HIS 196.A O no hydrogen 2.912 N/A TRP 100.A N VAL 146.A O no hydrogen 2.861 N/A TRP 100.A NE1 ASP 106.A OD2 no hydrogen 2.936 N/A VAL 101.A N SER 198.A O no hydrogen 2.944 N/A ASP 102.A N VAL 148.A O no hydrogen 3.187 N/A ALA 103.A N ASP 202.A OD1 no hydrogen 2.996 N/A HIS 104.A N ASP 102.A OD1 no hydrogen 2.739 N/A HIS 104.A ND1 ASP 202.A OD2 no hydrogen 2.949 N/A PHE 107.A N GLU 157.A OE2 no hydrogen 2.786 N/A ASN 108.A N GLY 119.A O no hydrogen 3.151 N/A ASN 108.A ND2 THR 112.A OG1 no hydrogen 2.722 N/A THR 109.A N THR 112.A OG1 no hydrogen 2.697 N/A THR 109.A OG1 GLU 111.A OE1 no hydrogen 3.482 N/A THR 109.A OG1 THR 112.A OG1 no hydrogen 3.302 N/A THR 112.A N THR 109.A OG1 no hydrogen 3.266 N/A THR 112.A OG1 THR 109.A O no hydrogen 3.290 N/A THR 112.A OG1 THR 109.A OG1 no hydrogen 3.302 N/A SER 113.A N THR 109.A O no hydrogen 3.180 N/A GLY 119.A N ASN 116.A O no hydrogen 3.171 N/A MET 120.A N VAL 117.A O no hydrogen 2.796 N/A LEU 122.A N ASP 106.A O no hydrogen 3.054 N/A ALA 123.A N ASP 106.A O no hydrogen 3.352 N/A VAL 124.A N MET 120.A O no hydrogen 2.976 N/A LEU 125.A N PRO 121.A O no hydrogen 2.876 N/A SER 126.A N LEU 122.A O no hydrogen 3.024 N/A SER 126.A OG LEU 122.A O no hydrogen 2.954 N/A GLY 127.A N VAL 124.A O no hydrogen 2.689 N/A LEU 128.A N ALA 123.A O no hydrogen 2.981 N/A ARG 132.A NE GLU 51.A OE1 no hydrogen 3.412 N/A ARG 132.A NE GLU 51.A OE2 no hydrogen 2.751 N/A ARG 132.A NH2 GLU 51.A OE1 no hydrogen 2.858 N/A LEU 133.A N HIS 130.A O no hydrogen 2.955 N/A THR 134.A N HIS 130.A O no hydrogen 3.022 N/A THR 134.A OG1 HIS 130.A O no hydrogen 3.401 N/A THR 134.A OG1 PRO 131.A O no hydrogen 3.513 N/A GLU 135.A N PRO 131.A O no hydrogen 2.962 N/A VAL 136.A N LEU 133.A O no hydrogen 3.322 N/A PHE 137.A N LEU 133.A O no hydrogen 2.868 N/A ARG 138.A N THR 134.A O no hydrogen 3.078 N/A ALA 139.A N LEU 125.A O no hydrogen 2.905 N/A VAL 140.A N LEU 125.A O no hydrogen 3.043 N/A LYS 143.A N ASP 141.A OD1 no hydrogen 2.840 N/A ASP 144.A N ASP 141.A O no hydrogen 2.673 N/A VAL 145.A N PRO 142.A O no hydrogen 3.337 N/A VAL 146.A N VAL 98.A O no hydrogen 2.915 N/A LEU 147.A N ARG 167.A O no hydrogen 3.021 N/A VAL 148.A N TRP 100.A O no hydrogen 2.889 N/A GLY 149.A N TYR 169.A O no hydrogen 2.916 N/A ARG 151.A N ALA 103.A O no hydrogen 2.892 N/A ARG 151.A NE GLY 149.A O no hydrogen 3.478 N/A ARG 151.A NH1 ASP 202.A O no hydrogen 3.156 N/A ARG 151.A NH1 VAL 216.A O no hydrogen 2.866 N/A ARG 151.A NH2 GLY 149.A O no hydrogen 3.282 N/A ARG 151.A NH2 VAL 203.A O no hydrogen 2.347 N/A SER 152.A N ALA 103.A O no hydrogen 3.230 N/A ASP 154.A N GLU 157.A OE1 no hydrogen 3.030 N/A LYS 158.A N ASP 154.A O no hydrogen 3.123 N/A ARG 159.A N PRO 155.A O no hydrogen 3.349 N/A LEU 160.A N GLY 156.A O no hydrogen 3.052 N/A LEU 161.A N GLU 157.A O no hydrogen 2.825 N/A LYS 162.A N LYS 158.A O no hydrogen 2.992 N/A GLU 163.A N ARG 159.A O no hydrogen 2.808 N/A ALA 164.A N LEU 160.A O no hydrogen 2.773 N/A GLY 165.A N LYS 162.A O no hydrogen 3.102 N/A VAL 166.A N LEU 161.A O no hydrogen 3.160 N/A ARG 167.A NH1 TYR 169.A OH no hydrogen 2.971 N/A TYR 169.A N LEU 147.A O no hydrogen 2.818 N/A TYR 169.A OH GLU 185.A OE1 no hydrogen 2.560 N/A THR 170.A N GLU 173.A OE1 no hydrogen 2.850 N/A THR 170.A OG1 GLU 173.A OE1 no hydrogen 2.587 N/A MET 171.A N VAL 150.A O no hydrogen 2.912 N/A HIS 172.A N THR 170.A OG1 no hydrogen 3.115 N/A HIS 172.A ND1 GLU 173.A OE2 no hydrogen 3.295 N/A VAL 174.A N THR 170.A O no hydrogen 2.986 N/A ASP 175.A N MET 171.A O no hydrogen 2.857 N/A ARG 176.A N HIS 172.A O no hydrogen 2.987 N/A LEU 177.A N GLU 173.A O no hydrogen 2.710 N/A GLY 178.A N VAL 174.A O no hydrogen 2.747 N/A ARG 181.A NE GLU 185.A OE2 no hydrogen 3.123 N/A ILE 182.A N GLY 178.A O no hydrogen 3.188 N/A ALA 183.A N VAL 179.A O no hydrogen 2.764 N/A GLU 184.A N ALA 180.A O no hydrogen 3.170 N/A GLU 185.A N ARG 181.A O no hydrogen 2.893 N/A VAL 186.A N ILE 182.A O no hydrogen 2.823 N/A LEU 187.A N ALA 183.A O no hydrogen 3.144 N/A LYS 188.A N GLU 184.A O no hydrogen 3.060 N/A HIS 189.A N GLU 185.A O no hydrogen 2.860 N/A LEU 190.A N VAL 186.A O no hydrogen 3.018 N/A GLN 191.A N LYS 188.A O no hydrogen 3.029 N/A LEU 193.A N LEU 190.A O no hydrogen 3.253 N/A LEU 195.A N ARG 237.A O no hydrogen 2.711 N/A HIS 196.A N GLY 97.A O no hydrogen 2.897 N/A VAL 197.A N SER 240.A O no hydrogen 2.947 N/A SER 198.A N VAL 99.A O no hydrogen 2.925 N/A SER 198.A OG HIS 80.A NE2 no hydrogen 2.710 N/A SER 198.A OG SER 83.A OG no hydrogen 3.165 N/A SER 198.A OG ASP 242.A OD2 no hydrogen 2.935 N/A LEU 199.A N ASP 242.A O no hydrogen 2.882 N/A ASP 200.A N VAL 101.A O no hydrogen 2.898 N/A ALA 201.A N VAL 244.A O no hydrogen 3.119 N/A ASP 202.A N ASP 200.A OD1 no hydrogen 2.841 N/A VAL 203.A N ASP 200.A O no hydrogen 3.043 N/A LEU 204.A N ALA 201.A O no hydrogen 3.237 N/A ASP 205.A N LEU 220.A O no hydrogen 2.966 N/A THR 207.A N ASP 205.A OD2 no hydrogen 3.115 N/A LEU 208.A N ASP 205.A O no hydrogen 2.853 N/A ALA 209.A N ASP 205.A O no hydrogen 2.830 N/A GLY 211.A N THR 256.A OG1 no hydrogen 2.988 N/A VAL 212.A N PRO 210.A O no hydrogen 2.720 N/A GLY 218.A N ASP 205.A OD1 no hydrogen 3.026 N/A GLY 219.A N ASP 205.A OD1 no hydrogen 2.952 N/A LEU 220.A N VAL 203.A O no hydrogen 3.006 N/A THR 221.A N GLU 224.A OE1 no hydrogen 3.018 N/A GLU 224.A N THR 221.A OG1 no hydrogen 2.982 N/A ALA 225.A N THR 221.A O no hydrogen 3.054 N/A HIS 226.A N TYR 222.A O no hydrogen 3.109 N/A HIS 226.A ND1 SER 266.A OG no hydrogen 2.877 N/A LEU 227.A N ARG 223.A O no hydrogen 2.813 N/A LEU 228.A N GLU 224.A O no hydrogen 2.949 N/A MET 229.A N ALA 225.A O no hydrogen 3.124 N/A GLU 230.A N HIS 226.A O no hydrogen 2.840 N/A ILE 231.A N LEU 227.A O no hydrogen 2.941 N/A LEU 232.A N LEU 228.A O no hydrogen 3.092 N/A ALA 233.A N MET 229.A O no hydrogen 2.850 N/A GLU 234.A N GLU 230.A O no hydrogen 2.956 N/A SER 235.A N LEU 232.A O no hydrogen 3.231 N/A SER 235.A OG LEU 232.A O no hydrogen 2.630 N/A GLY 236.A N ALA 233.A O no hydrogen 2.932 N/A ARG 237.A N SER 235.A OG no hydrogen 3.072 N/A ARG 237.A NH1 LEU 190.A O no hydrogen 2.709 N/A ARG 237.A NH1 LEU 193.A O no hydrogen 2.810 N/A ARG 237.A NH2 LEU 187.A O no hydrogen 2.865 N/A GLN 239.A N LEU 195.A O no hydrogen 2.732 N/A GLN 239.A NE2 ALA 90.A O no hydrogen 3.055 N/A GLN 239.A NE2 SER 240.A OG no hydrogen 3.054 N/A LEU 241.A N PRO 73.A O no hydrogen 3.009 N/A ASP 242.A N VAL 197.A O no hydrogen 2.929 N/A LEU 243.A N VAL 75.A O no hydrogen 2.875 N/A VAL 244.A N LEU 199.A O no hydrogen 2.978 N/A GLU 245.A N GLY 78.A O no hydrogen 3.009 N/A ASN 247.A N GLY 211.A O no hydrogen 2.851 N/A ILE 249.A N ASN 247.A OD1 no hydrogen 3.149 N/A LEU 250.A N ASN 247.A O no hydrogen 3.009 N/A ASP 251.A N PRO 248.A O no hydrogen 3.156 N/A GLU 252.A N ASP 251.A OD1 no hydrogen 2.623 N/A ASN 254.A ND2 ALA 20.A O no hydrogen 3.193 N/A ARG 255.A N GLU 252.A O no hydrogen 3.034 N/A THR 256.A N ASP 251.A OD1 no hydrogen 3.376 N/A THR 256.A N ASP 251.A OD2 no hydrogen 2.945 N/A THR 256.A OG1 ASP 251.A OD1 no hydrogen 2.841 N/A GLU 258.A N ASN 254.A O no hydrogen 3.046 N/A MET 259.A N ARG 255.A O no hydrogen 2.895 N/A LEU 260.A N THR 256.A O no hydrogen 3.061 N/A VAL 261.A N ALA 257.A O no hydrogen 2.970 N/A GLY 262.A N GLU 258.A O no hydrogen 3.058 N/A LEU 263.A N MET 259.A O no hydrogen 3.028 N/A ALA 264.A N LEU 260.A O no hydrogen 2.926 N/A LEU 265.A N VAL 261.A O no hydrogen 3.046 N/A SER 266.A N GLY 262.A O no hydrogen 3.128 N/A SER 266.A OG HIS 226.A ND1 no hydrogen 2.877 N/A SER 266.A OG GLY 262.A O no hydrogen 3.520 N/A LEU 267.A N LEU 263.A O no hydrogen 2.942 N/A LEU 268.A N ALA 264.A O no hydrogen 2.915 N/A GLY 269.A N SER 266.A O no hydrogen 3.183 N/A LYS 270.A N LEU 265.A O no hydrogen 2.949 N/A