Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2f3d_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 4.A N PHE 184.A O no hydrogen 2.832 N/A ARG 6.A N THR 3.A OG1 no hydrogen 3.086 N/A PHE 7.A N THR 3.A O no hydrogen 2.822 N/A VAL 8.A N LEU 4.A O no hydrogen 2.766 N/A MET 9.A N THR 5.A O no hydrogen 3.157 N/A GLU 10.A N ARG 6.A O no hydrogen 2.735 N/A GLU 11.A N PHE 7.A O no hydrogen 2.877 N/A GLY 12.A N VAL 8.A O no hydrogen 2.899 N/A ARG 13.A N MET 9.A O no hydrogen 2.818 N/A LYS 14.A N GLU 10.A O no hydrogen 3.272 N/A LYS 14.A NZ GLU 10.A OE1 no hydrogen 3.225 N/A ALA 15.A N GLU 11.A O no hydrogen 3.307 N/A ARG 16.A NH2 GLY 17.A O no hydrogen 3.429 N/A GLY 17.A N GLY 12.A O no hydrogen 3.328 N/A GLN 23.A N GLY 19.A O no hydrogen 3.029 N/A LEU 24.A N GLU 20.A O no hydrogen 2.782 N/A LEU 25.A N MET 21.A O no hydrogen 2.899 N/A ASN 26.A N THR 22.A O no hydrogen 2.838 N/A SER 27.A N GLN 23.A O no hydrogen 2.867 N/A SER 27.A OG GLN 23.A O no hydrogen 3.016 N/A SER 27.A OG VAL 75.A O no hydrogen 3.450 N/A LEU 28.A N LEU 24.A O no hydrogen 3.099 N/A CYS 29.A N LEU 25.A O no hydrogen 3.014 N/A CYS 29.A SG LEU 25.A O no hydrogen 3.187 N/A THR 30.A N ASN 26.A O no hydrogen 3.077 N/A THR 30.A OG1 ASN 26.A O no hydrogen 3.260 N/A ALA 31.A N SER 27.A O no hydrogen 2.955 N/A VAL 32.A N LEU 28.A O no hydrogen 2.784 N/A LYS 33.A N CYS 29.A O no hydrogen 2.987 N/A LYS 33.A NZ GLY 182.A O no hydrogen 2.901 N/A ALA 34.A N THR 30.A O no hydrogen 3.017 N/A ILE 35.A N ALA 31.A O no hydrogen 2.868 N/A SER 36.A N VAL 32.A O no hydrogen 2.872 N/A SER 36.A OG THR 162.A OG1 no hydrogen 2.784 N/A THR 37.A N LYS 33.A O no hydrogen 3.010 N/A THR 37.A OG1 LYS 33.A O no hydrogen 2.881 N/A ALA 38.A N ALA 34.A O no hydrogen 3.142 N/A VAL 39.A N ILE 35.A O no hydrogen 2.799 N/A ARG 40.A N SER 36.A O no hydrogen 2.893 N/A ARG 40.A NH1 GLY 159.A O no hydrogen 2.909 N/A ARG 40.A NH2 GLY 159.A O no hydrogen 2.869 N/A LYS 41.A N ALA 38.A O no hydrogen 3.177 N/A ALA 42.A N VAL 39.A O no hydrogen 3.353 N/A ALA 45.A N LYS 41.A O no hydrogen 3.210 N/A HIS 46.A N GLY 43.A O no hydrogen 3.118 N/A LEU 47.A N ALA 42.A O no hydrogen 2.930 N/A ALA 51.A N VAL 61.A O no hydrogen 2.741 N/A ASN 55.A N ASP 59.A O no hydrogen 3.272 N/A THR 57.A OG1 ASN 55.A OD1 no hydrogen 2.402 N/A THR 57.A OG1 ASP 59.A OD2 no hydrogen 3.234 N/A GLY 58.A N ASN 55.A O no hydrogen 2.814 N/A ASP 59.A N ASN 55.A OD1 no hydrogen 2.985 N/A VAL 61.A N SER 53.A O no hydrogen 2.960 N/A LYS 62.A N ASP 65.A OD1 no hydrogen 2.883 N/A LYS 62.A NZ SER 114.A O no hydrogen 3.221 N/A LYS 62.A NZ SER 114.A OG no hydrogen 2.945 N/A LYS 63.A N GLY 49.A O no hydrogen 2.949 N/A LYS 63.A NZ HIS 46.A O no hydrogen 2.554 N/A LYS 63.A NZ TYR 48.A O no hydrogen 2.770 N/A VAL 66.A N LYS 62.A O no hydrogen 3.184 N/A LEU 67.A N LYS 63.A O no hydrogen 2.990 N/A SER 68.A N LEU 64.A O no hydrogen 2.887 N/A SER 68.A OG LEU 64.A O no hydrogen 2.836 N/A SER 68.A OG ASP 65.A O no hydrogen 2.908 N/A ASN 69.A N ASP 65.A O no hydrogen 2.885 N/A ASN 69.A ND2 ASP 90.A OD2 no hydrogen 3.338 N/A ASP 70.A N VAL 66.A O no hydrogen 2.834 N/A LEU 71.A N LEU 67.A O no hydrogen 2.934 N/A VAL 72.A N SER 68.A O no hydrogen 2.989 N/A ILE 73.A N ASN 69.A O no hydrogen 2.994 N/A ASN 74.A N ASP 70.A O no hydrogen 2.986 N/A VAL 75.A N LEU 71.A O no hydrogen 2.958 N/A LEU 76.A N VAL 72.A O no hydrogen 2.943 N/A LYS 77.A N ILE 73.A O no hydrogen 2.958 N/A SER 78.A N ASN 74.A O no hydrogen 3.297 N/A SER 78.A OG ASN 74.A O no hydrogen 3.124 N/A SER 78.A OG VAL 75.A O no hydrogen 3.367 N/A SER 79.A N LEU 76.A O no hydrogen 3.302 N/A SER 79.A OG LEU 76.A O no hydrogen 2.630 N/A ALA 81.A N SER 79.A OG no hydrogen 3.276 N/A THR 82.A OG1 LEU 76.A O no hydrogen 3.389 N/A CYS 83.A N TYR 104.A O no hydrogen 2.962 N/A CYS 83.A SG TYR 104.A O no hydrogen 3.662 N/A LEU 85.A N ILE 94.A O no hydrogen 2.766 N/A VAL 86.A N VAL 106.A O no hydrogen 2.805 N/A SER 87.A OG ASN 69.A OD1 no hydrogen 2.581 N/A GLU 88.A N PHE 108.A O no hydrogen 3.199 N/A GLU 89.A N SER 87.A OG no hydrogen 3.026 N/A ASP 90.A N SER 87.A O no hydrogen 3.113 N/A ASN 92.A ND2 GLU 140.A OE1 no hydrogen 3.526 N/A ALA 93.A N GLU 140.A OE1 no hydrogen 3.027 N/A ILE 94.A N LEU 85.A O no hydrogen 2.623 N/A VAL 96.A N CYS 83.A O no hydrogen 3.109 N/A LYS 100.A N GLU 97.A O no hydrogen 2.944 N/A ARG 101.A N PRO 98.A O no hydrogen 3.124 N/A ARG 101.A NE VAL 96.A O no hydrogen 2.532 N/A ARG 101.A NH1 GLU 137.A OE2 no hydrogen 3.562 N/A GLY 102.A N THR 82.A O no hydrogen 2.767 N/A LYS 103.A N GLU 20.A OE1 no hydrogen 3.125 N/A TYR 104.A N ALA 81.A O no hydrogen 2.942 N/A VAL 105.A N TYR 130.A O no hydrogen 2.740 N/A VAL 106.A N VAL 84.A O no hydrogen 2.990 N/A CYS 107.A N GLY 128.A O no hydrogen 2.966 N/A PHE 108.A N VAL 86.A O no hydrogen 2.758 N/A ASP 109.A N ILE 126.A O no hydrogen 2.766 N/A ASP 112.A N GLY 124.A O no hydrogen 2.716 N/A ASN 116.A N GLY 113.A O no hydrogen 2.766 N/A ASN 116.A ND2 VAL 236.A O no hydrogen 2.896 N/A ASN 116.A ND2 SER 238.A OG no hydrogen 2.968 N/A ILE 117.A N SER 114.A O no hydrogen 3.145 N/A CYS 119.A SG ASN 116.A O no hydrogen 3.561 N/A CYS 119.A SG ASN 116.A OD1 no hydrogen 3.409 N/A LEU 120.A N ILE 117.A O no hydrogen 3.091 N/A VAL 121.A N ASN 116.A O no hydrogen 3.174 N/A GLY 124.A N ASP 112.A O no hydrogen 3.054 N/A THR 125.A N ALA 156.A O no hydrogen 2.910 N/A THR 125.A OG1 PRO 110.A O no hydrogen 2.697 N/A THR 125.A OG1 TYR 158.A OH no hydrogen 2.747 N/A ILE 126.A N ASP 109.A O no hydrogen 2.939 N/A PHE 127.A N GLY 154.A O no hydrogen 3.007 N/A GLY 128.A N CYS 107.A O no hydrogen 2.831 N/A ILE 129.A N ALA 152.A O no hydrogen 2.657 N/A TYR 130.A N VAL 105.A O no hydrogen 2.796 N/A LYS 132.A N LYS 103.A O no hydrogen 2.730 N/A LYS 132.A NZ ASP 136.A O no hydrogen 2.783 N/A LYS 132.A NZ ASP 142.A OD1 no hydrogen 3.324 N/A LYS 132.A NZ ASP 142.A OD2 no hydrogen 3.528 N/A SER 134.A OG ASP 142.A OD1 no hydrogen 3.123 N/A SER 139.A N ASP 142.A OD2 no hydrogen 2.733 N/A LYS 141.A N SER 139.A OG no hydrogen 3.315 N/A ASP 142.A N SER 139.A O no hydrogen 2.940 N/A ALA 143.A N GLU 140.A O no hydrogen 3.122 N/A LEU 144.A N LYS 141.A O no hydrogen 3.113 N/A GLN 145.A NE2 ARG 131.A O no hydrogen 3.367 N/A GLN 145.A NE2 ASP 142.A O no hydrogen 2.848 N/A ARG 148.A N LEU 294.A O no hydrogen 2.884 N/A ASN 149.A N PRO 146.A O no hydrogen 2.922 N/A ASN 149.A ND2 GLN 145.A OE1 no hydrogen 3.390 N/A LEU 150.A N GLY 147.A O no hydrogen 2.902 N/A VAL 151.A N ILE 129.A O no hydrogen 2.812 N/A ALA 152.A N ILE 129.A O no hydrogen 3.432 N/A ALA 153.A N ALA 167.A O no hydrogen 2.991 N/A GLY 154.A N PHE 127.A O no hydrogen 3.026 N/A TYR 155.A N VAL 165.A O no hydrogen 2.993 N/A TYR 155.A OH HIS 244.A ND1 no hydrogen 2.596 N/A ALA 156.A N THR 125.A O no hydrogen 2.731 N/A LEU 157.A N MET 163.A O no hydrogen 2.676 N/A TYR 158.A N ILE 123.A O no hydrogen 2.799 N/A TYR 158.A OH THR 125.A OG1 no hydrogen 2.747 N/A GLY 159.A N ALA 161.A O no hydrogen 3.090 N/A THR 162.A OG1 SER 36.A OG no hydrogen 2.784 N/A MET 163.A N LEU 157.A O no hydrogen 2.931 N/A LEU 164.A N PHE 175.A O no hydrogen 2.771 N/A VAL 165.A N TYR 155.A O no hydrogen 2.810 N/A LEU 166.A N ASN 173.A O no hydrogen 2.975 N/A ALA 167.A N ALA 153.A O no hydrogen 2.712 N/A MET 168.A N GLY 171.A O no hydrogen 3.088 N/A GLY 171.A N MET 168.A O no hydrogen 2.900 N/A ASN 173.A N LEU 166.A O no hydrogen 2.990 N/A CYS 174.A N ASP 188.A O no hydrogen 2.883 N/A PHE 175.A N LEU 164.A O no hydrogen 2.838 N/A MET 176.A N ILE 185.A O no hydrogen 2.762 N/A LEU 177.A N THR 162.A O no hydrogen 2.830 N/A ASP 178.A N GLU 183.A O no hydrogen 2.830 N/A ALA 180.A N ASP 178.A OD1 no hydrogen 3.014 N/A ILE 181.A N ASP 178.A O no hydrogen 3.232 N/A GLY 182.A N ASP 178.A O no hydrogen 2.843 N/A ILE 185.A N MET 176.A O no hydrogen 2.665 N/A LEU 186.A N VAL 2.A O no hydrogen 2.872 N/A VAL 187.A N CYS 174.A O no hydrogen 2.859 N/A ASP 188.A N CYS 174.A O no hydrogen 3.324 N/A ASP 190.A N ASN 173.A OD1 no hydrogen 2.873 N/A VAL 191.A N VAL 172.A O no hydrogen 2.848 N/A LYS 192.A NZ LYS 281.A O no hydrogen 3.051 N/A ILE 193.A N ALA 282.A O no hydrogen 2.837 N/A LYS 196.A NZ TYR 231.A OH no hydrogen 3.277 N/A LYS 196.A NZ ASP 314.A OD1 no hydrogen 3.453 N/A GLY 197.A N ASP 314.A OD2 no hydrogen 2.717 N/A TYR 200.A N GLY 232.A O no hydrogen 3.056 N/A TYR 200.A OH GLU 204.A OE1 no hydrogen 2.700 N/A SER 201.A N ILE 252.A O no hydrogen 2.772 N/A SER 201.A OG ARG 234.A O no hydrogen 2.695 N/A GLY 205.A N ASN 203.A OD1 no hydrogen 2.882 N/A ALA 207.A N GLU 204.A O no hydrogen 3.001 N/A GLU 209.A N TYR 206.A O no hydrogen 2.759 N/A PHE 210.A N ALA 207.A O no hydrogen 3.321 N/A ILE 214.A N ASP 211.A OD1 no hydrogen 2.897 N/A THR 215.A N ASP 211.A O no hydrogen 3.140 N/A THR 215.A OG1 ASP 211.A O no hydrogen 3.142 N/A GLU 216.A N PRO 212.A O no hydrogen 2.917 N/A TYR 217.A N ALA 213.A O no hydrogen 2.933 N/A ILE 218.A N ILE 214.A O no hydrogen 2.982 N/A GLN 219.A N THR 215.A O no hydrogen 3.176 N/A ARG 220.A N GLU 216.A O no hydrogen 3.028 N/A ARG 220.A NH1 GLU 317.A OE2 no hydrogen 2.976 N/A LYS 221.A N TYR 217.A O no hydrogen 2.928 N/A LYS 221.A NZ GLU 317.A OE1 no hydrogen 3.500 N/A LYS 222.A N ILE 218.A O no hydrogen 3.090 N/A LYS 222.A NZ GLU 204.A OE2 no hydrogen 2.669 N/A PHE 223.A N GLN 219.A O no hydrogen 2.756 N/A ASN 227.A N PRO 224.A O no hydrogen 3.107 N/A SER 228.A N ASP 226.A OD2 no hydrogen 2.962 N/A SER 228.A OG ASP 226.A OD1 no hydrogen 3.356 N/A SER 228.A OG ASP 226.A OD2 no hydrogen 2.685 N/A TYR 231.A N LYS 221.A O no hydrogen 3.018 N/A TYR 231.A OH ASP 314.A OD1 no hydrogen 2.580 N/A GLY 232.A N SER 198.A O no hydrogen 2.866 N/A ARG 234.A N TYR 200.A O no hydrogen 3.276 N/A ARG 234.A NH1 ALA 233.A O no hydrogen 2.943 N/A VAL 236.A N ASP 242.A OD1 no hydrogen 2.786 N/A GLY 237.A N ASP 242.A OD2 no hydrogen 2.974 N/A SER 238.A OG SER 122.A O no hydrogen 2.623 N/A VAL 240.A N ASP 112.A OD2 no hydrogen 2.891 N/A ASP 242.A N SER 238.A O no hydrogen 3.020 N/A VAL 243.A N MET 239.A O no hydrogen 2.797 N/A HIS 244.A N VAL 240.A O no hydrogen 2.961 N/A HIS 244.A ND1 TYR 155.A OH no hydrogen 2.596 N/A ARG 245.A N ALA 241.A O no hydrogen 3.037 N/A ARG 245.A NH1 ASP 242.A OD1 no hydrogen 2.927 N/A ARG 245.A NH2 ASP 242.A OD1 no hydrogen 3.312 N/A THR 246.A N ASP 242.A O no hydrogen 3.040 N/A THR 246.A OG1 ASP 242.A O no hydrogen 2.710 N/A LEU 247.A N VAL 243.A O no hydrogen 2.895 N/A VAL 248.A N HIS 244.A O no hydrogen 3.073 N/A TYR 249.A N ARG 245.A O no hydrogen 2.743 N/A GLY 250.A N THR 246.A O no hydrogen 2.703 N/A GLY 251.A N SER 311.A OG no hydrogen 2.861 N/A ILE 252.A N ILE 199.A O no hydrogen 3.005 N/A PHE 253.A N LEU 309.A O no hydrogen 2.848 N/A MET 254.A N SER 201.A O no hydrogen 2.761 N/A TYR 255.A N ILE 307.A O no hydrogen 2.866 N/A ASN 258.A N SER 261.A O no hydrogen 2.909 N/A LYS 259.A N GLU 209.A OE2 no hydrogen 3.082 N/A LYS 259.A NZ GLU 209.A O no hydrogen 3.162 N/A LYS 260.A NZ GLU 209.A OE1 no hydrogen 2.709 N/A LYS 260.A NZ GLU 209.A OE2 no hydrogen 3.099 N/A SER 261.A N ASN 258.A OD1 no hydrogen 2.677 N/A GLY 264.A N SER 261.A O no hydrogen 2.903 N/A ARG 267.A N GLU 271.A OE2 no hydrogen 2.667 N/A ARG 267.A NE GLU 271.A OE2 no hydrogen 2.735 N/A ARG 267.A NH1 ASP 59.A OD2 no hydrogen 3.120 N/A ARG 267.A NH1 GLU 88.A OE2 no hydrogen 3.065 N/A ARG 267.A NH2 GLU 271.A OE1 no hydrogen 2.842 N/A ARG 267.A NH2 GLU 271.A OE2 no hydrogen 3.370 N/A LEU 268.A N GLN 303.A O no hydrogen 2.956 N/A TYR 270.A OH HIS 302.A ND1 no hydrogen 2.671 N/A GLU 271.A N ARG 267.A O no hydrogen 3.074 N/A CYS 272.A N ARG 267.A O no hydrogen 2.886 N/A CYS 272.A SG ARG 267.A O no hydrogen 3.728 N/A CYS 272.A SG ALA 305.A O no hydrogen 3.803 N/A ASN 273.A N LEU 268.A O no hydrogen 2.857 N/A ASN 273.A ND2 VAL 293.A O no hydrogen 3.461 N/A MET 275.A N GLU 271.A O no hydrogen 3.439 N/A ALA 276.A N CYS 272.A O no hydrogen 2.773 N/A TYR 277.A N ASN 273.A O no hydrogen 2.901 N/A VAL 278.A N PRO 274.A O no hydrogen 3.039 N/A MET 279.A N MET 275.A O no hydrogen 2.904 N/A GLU 280.A N ALA 276.A O no hydrogen 2.915 N/A LYS 281.A N TYR 277.A O no hydrogen 2.974 N/A ALA 282.A N VAL 278.A O no hydrogen 3.085 N/A ALA 282.A N MET 279.A O no hydrogen 3.060 N/A GLY 283.A N GLU 280.A O no hydrogen 3.080 N/A GLY 284.A N MET 279.A O no hydrogen 2.608 N/A LEU 285.A N GLY 310.A O no hydrogen 3.027 N/A THR 287.A N ILE 308.A O no hydrogen 2.807 N/A THR 287.A OG1 GLU 291.A O no hydrogen 3.090 N/A THR 288.A N GLU 291.A O no hydrogen 2.967 N/A THR 288.A OG1 GLU 291.A O no hydrogen 3.469 N/A GLY 289.A N THR 287.A OG1 no hydrogen 2.798 N/A LYS 290.A N THR 288.A OG1 no hydrogen 2.979 N/A GLU 291.A N THR 288.A OG1 no hydrogen 3.108 N/A VAL 293.A N ALA 286.A O no hydrogen 3.141 N/A ASP 295.A N ALA 292.A O no hydrogen 3.024 N/A ILE 296.A N VAL 293.A O no hydrogen 3.241 N/A THR 299.A N GLN 303.A OE1 no hydrogen 2.734 N/A THR 299.A OG1 GLN 303.A OE1 no hydrogen 3.388 N/A ASP 300.A N GLN 303.A OE1 no hydrogen 3.249 N/A HIS 302.A N ASP 300.A OD1 no hydrogen 2.710 N/A HIS 302.A ND1 TYR 270.A OH no hydrogen 2.671 N/A HIS 302.A NE2 ASP 90.A O no hydrogen 2.812 N/A HIS 302.A NE2 LYS 91.A O no hydrogen 3.102 N/A GLN 303.A N ASP 300.A O no hydrogen 3.185 N/A ARG 304.A NH1 LYS 265.A O no hydrogen 2.527 N/A ALA 305.A N LEU 266.A O no hydrogen 2.992 N/A ILE 307.A N TYR 255.A O no hydrogen 3.060 N/A ILE 308.A N THR 287.A O no hydrogen 2.724 N/A LEU 309.A N PHE 253.A O no hydrogen 2.938 N/A GLY 310.A N LEU 285.A O no hydrogen 3.039 N/A SER 311.A N GLY 251.A O no hydrogen 2.806 N/A SER 311.A OG LYS 194.A O no hydrogen 2.859 N/A SER 311.A OG GLY 251.A O no hydrogen 3.523 N/A GLU 313.A N LYS 195.A O no hydrogen 2.986 N/A VAL 315.A N SER 311.A O no hydrogen 2.975 N/A THR 316.A N PRO 312.A O no hydrogen 2.865 N/A THR 316.A OG1 PRO 312.A O no hydrogen 2.651 N/A GLU 317.A N GLU 313.A O no hydrogen 3.050 N/A LEU 318.A N ASP 314.A O no hydrogen 3.236 N/A LEU 319.A N VAL 315.A O no hydrogen 2.903 N/A GLU 320.A N THR 316.A O no hydrogen 2.857 N/A ILE 321.A N GLU 317.A O no hydrogen 3.216 N/A TYR 322.A N LEU 318.A O no hydrogen 3.037 N/A TYR 322.A OH ASP 211.A OD2 no hydrogen 2.575 N/A GLN 323.A N LEU 319.A O no hydrogen 2.877 N/A GLN 323.A NE2 LEU 319.A O no hydrogen 3.676 N/A LYS 324.A N GLU 320.A O no hydrogen 2.864 N/A LYS 324.A NZ GLU 216.A OE2 no hydrogen 2.764 N/A HIS 325.A N ILE 321.A O no hydrogen 3.035 N/A HIS 325.A NE2 GLU 216.A OE1 no hydrogen 2.618 N/A ALA 326.A N TYR 322.A O no hydrogen 3.027 N/A ALA 326.A N GLN 323.A O no hydrogen 3.159 N/A ALA 327.A N GLN 323.A O no hydrogen 3.142 N/A LYS 328.A N HIS 325.A O no hydrogen 3.347 N/A