Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2f6k_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A N ASP 46.A OD2 no hydrogen 3.445 N/A SER 1.A OG ASP 46.A OD1 no hydrogen 3.267 N/A LYS 2.A N ASP 46.A O no hydrogen 2.788 N/A LYS 2.A NZ ASN 45.A O no hydrogen 3.071 N/A ILE 3.A N PHE 290.A O no hydrogen 2.860 N/A ASP 4.A N TYR 49.A O no hydrogen 2.728 N/A PHE 5.A N TYR 256.A O no hydrogen 2.980 N/A HIS 6.A N ASP 4.A OD1 no hydrogen 3.106 N/A HIS 6.A ND1 ASP 233.A OD1 no hydrogen 2.682 N/A HIS 8.A N ILE 260.A O no hydrogen 2.774 N/A HIS 8.A ND1 SER 53.A O no hydrogen 2.883 N/A TYR 9.A OH ALA 74.A O no hydrogen 2.853 N/A TYR 14.A OH PRO 57.A O no hydrogen 2.779 N/A VAL 15.A N PRO 11.A O no hydrogen 3.024 N/A GLU 16.A N THR 12.A O no hydrogen 2.950 N/A ALA 17.A N SER 13.A O no hydrogen 2.999 N/A LEU 18.A N TYR 14.A O no hydrogen 2.963 N/A LYS 19.A N VAL 15.A O no hydrogen 3.122 N/A ARG 20.A N GLU 16.A O no hydrogen 3.027 N/A ARG 20.A NH2 GLU 66.A OE2 no hydrogen 2.514 N/A HIS 21.A N ALA 17.A O no hydrogen 2.939 N/A HIS 21.A NE2 GLU 66.A OE2 no hydrogen 2.814 N/A VAL 22.A N LEU 18.A O no hydrogen 2.894 N/A GLY 28.A N ASP 25.A O no hydrogen 2.822 N/A TRP 29.A N PRO 26.A O no hydrogen 2.856 N/A TRP 29.A NE1 TYR 262.A O no hydrogen 3.041 N/A TRP 34.A NE1 THR 39.A OG1 no hydrogen 2.713 N/A LEU 38.A N THR 35.A O no hydrogen 3.234 N/A LEU 40.A N PRO 36.A O no hydrogen 3.046 N/A ASN 41.A N GLN 37.A O no hydrogen 2.834 N/A PHE 42.A N LEU 38.A O no hydrogen 2.963 N/A ARG 43.A NH1 ASN 41.A OD1 no hydrogen 2.558 N/A ASP 44.A N ASN 41.A O no hydrogen 3.045 N/A ASN 45.A ND2 PHE 42.A O no hydrogen 2.831 N/A SER 48.A N LYS 2.A O no hydrogen 2.878 N/A SER 48.A OG LYS 2.A O no hydrogen 3.502 N/A TYR 49.A N LYS 2.A O no hydrogen 3.448 N/A SER 50.A N GLN 88.A O no hydrogen 2.920 N/A ILE 51.A N ASP 4.A O no hydrogen 2.806 N/A LEU 52.A N GLY 90.A O no hydrogen 2.874 N/A SER 53.A N THR 7.A O no hydrogen 3.172 N/A SER 53.A OG HIS 8.A ND1 no hydrogen 3.130 N/A SER 55.A OG SER 56.A O no hydrogen 3.443 N/A SER 56.A OG ASP 27.A OD2 no hydrogen 3.496 N/A SER 56.A OG PRO 153.A O no hydrogen 3.086 N/A HIS 58.A N ASN 154.A OD1 no hydrogen 3.022 N/A HIS 58.A ND1 SER 125.A OG no hydrogen 2.818 N/A HIS 58.A NE2 LEU 95.A O no hydrogen 2.999 N/A GLU 66.A N ASP 63.A OD1 no hydrogen 3.014 N/A THR 67.A N ASP 63.A O no hydrogen 2.909 N/A THR 67.A OG1 VAL 59.A O no hydrogen 2.988 N/A THR 67.A OG1 ASP 63.A O no hydrogen 3.028 N/A ILE 68.A N LYS 64.A O no hydrogen 2.958 N/A ARG 69.A N ALA 65.A O no hydrogen 2.931 N/A LEU 70.A N GLU 66.A O no hydrogen 2.771 N/A VAL 71.A N THR 67.A O no hydrogen 2.982 N/A GLU 72.A N ILE 68.A O no hydrogen 3.146 N/A ALA 73.A N ARG 69.A O no hydrogen 2.945 N/A ALA 74.A N LEU 70.A O no hydrogen 2.952 N/A ASN 75.A N VAL 71.A O no hydrogen 2.901 N/A ASN 75.A ND2 SER 94.A O no hydrogen 3.209 N/A ASP 76.A N GLU 72.A O no hydrogen 2.965 N/A ASP 77.A N ALA 73.A O no hydrogen 3.189 N/A GLY 78.A N ALA 74.A O no hydrogen 3.008 N/A LYS 79.A N ASN 75.A O no hydrogen 2.893 N/A LYS 79.A NZ ASP 114.A OD1 no hydrogen 2.972 N/A SER 80.A N ASP 76.A O no hydrogen 2.737 N/A LEU 81.A N ASP 77.A O no hydrogen 2.923 N/A ALA 82.A N GLY 78.A O no hydrogen 3.083 N/A GLN 83.A N LYS 79.A O no hydrogen 2.989 N/A GLN 84.A N SER 80.A O no hydrogen 3.064 N/A TYR 85.A N LEU 81.A O no hydrogen 2.805 N/A GLN 88.A N TYR 85.A O no hydrogen 2.946 N/A LEU 89.A N TYR 85.A O no hydrogen 2.813 N/A GLY 90.A N SER 50.A O no hydrogen 2.971 N/A TYR 91.A OH ASP 114.A O no hydrogen 2.871 N/A LEU 92.A N LEU 52.A O no hydrogen 2.786 N/A ALA 93.A N GLY 118.A O no hydrogen 2.806 N/A SER 94.A N ASN 75.A OD1 no hydrogen 2.878 N/A ILE 97.A N LEU 95.A O no hydrogen 2.643 N/A TYR 99.A N PRO 96.A O no hydrogen 3.002 N/A ALA 103.A N TYR 99.A O no hydrogen 2.827 N/A VAL 104.A N GLU 100.A O no hydrogen 2.907 N/A LYS 105.A N LEU 101.A O no hydrogen 3.189 N/A THR 106.A N ASP 102.A O no hydrogen 3.013 N/A THR 106.A OG1 ASP 102.A O no hydrogen 3.322 N/A VAL 107.A N ALA 103.A O no hydrogen 2.901 N/A GLN 108.A N VAL 104.A O no hydrogen 3.255 N/A GLN 109.A N LYS 105.A O no hydrogen 3.117 N/A GLN 109.A NE2 ASP 114.A OD2 no hydrogen 2.904 N/A ALA 110.A N THR 106.A O no hydrogen 2.813 N/A LEU 111.A N VAL 107.A O no hydrogen 2.989 N/A ASP 112.A N GLN 108.A O no hydrogen 2.787 N/A GLN 113.A N GLN 109.A O no hydrogen 3.043 N/A ASP 114.A N GLN 109.A O no hydrogen 3.125 N/A ALA 116.A N ALA 110.A O no hydrogen 3.111 N/A LEU 117.A N TYR 91.A O no hydrogen 2.898 N/A VAL 119.A N ILE 148.A O no hydrogen 2.937 N/A THR 120.A N ALA 93.A O no hydrogen 2.832 N/A THR 120.A OG1 ALA 150.A O no hydrogen 3.360 N/A VAL 121.A N ALA 150.A O no hydrogen 2.848 N/A THR 123.A N HIS 152.A O no hydrogen 2.975 N/A THR 123.A OG1 ASP 176.A OD2 no hydrogen 2.431 N/A ASN 124.A ND2 GLU 155.A O no hydrogen 2.967 N/A ASN 124.A ND2 ASP 176.A OD1 no hydrogen 3.524 N/A ASN 124.A ND2 ASP 176.A OD2 no hydrogen 3.006 N/A SER 125.A N LEU 128.A O no hydrogen 2.946 N/A SER 125.A OG HIS 58.A ND1 no hydrogen 2.818 N/A SER 125.A OG ASN 60.A OD1 no hydrogen 3.233 N/A GLY 127.A N ASN 124.A OD1 no hydrogen 2.909 N/A LEU 128.A N SER 125.A O no hydrogen 2.981 N/A TYR 129.A OH ASP 176.A OD1 no hydrogen 2.627 N/A PHE 130.A N THR 123.A O no hydrogen 2.754 N/A GLY 131.A N TYR 139.A OH no hydrogen 2.792 N/A SER 132.A N TYR 129.A O no hydrogen 3.094 N/A LEU 135.A N SER 132.A O no hydrogen 3.009 N/A GLU 136.A N PRO 133.A O no hydrogen 3.275 N/A ARG 137.A N GLU 100.A OE2 no hydrogen 3.085 N/A ARG 137.A NH1 GLU 100.A OE1 no hydrogen 2.622 N/A ARG 137.A NH1 GLU 100.A OE2 no hydrogen 3.377 N/A VAL 138.A N LEU 135.A O no hydrogen 2.841 N/A TYR 139.A N LEU 135.A O no hydrogen 3.112 N/A TYR 139.A OH SER 132.A O no hydrogen 2.803 N/A GLN 140.A N GLU 136.A O no hydrogen 2.950 N/A GLU 141.A N ARG 137.A O no hydrogen 3.214 N/A LEU 142.A N VAL 138.A O no hydrogen 3.140 N/A ASP 143.A N TYR 139.A O no hydrogen 2.699 N/A ALA 144.A N GLN 140.A O no hydrogen 2.990 N/A ARG 145.A N LEU 142.A O no hydrogen 3.215 N/A ARG 145.A NE ASP 112.A OD1 no hydrogen 2.871 N/A ARG 145.A NE ASP 112.A OD2 no hydrogen 3.422 N/A ARG 145.A NH1 GLU 141.A O no hydrogen 2.755 N/A ARG 145.A NH1 GLU 141.A OE1 no hydrogen 2.700 N/A ARG 145.A NH2 ASP 112.A OD2 no hydrogen 2.822 N/A GLN 146.A N ASP 143.A O no hydrogen 3.067 N/A ALA 147.A N LEU 142.A O no hydrogen 3.079 N/A VAL 149.A N LYS 195.A O no hydrogen 2.837 N/A ALA 150.A N VAL 119.A O no hydrogen 2.903 N/A LEU 151.A N ILE 197.A O no hydrogen 3.097 N/A HIS 152.A N VAL 121.A O no hydrogen 2.773 N/A HIS 152.A ND1 PRO 153.A O no hydrogen 3.123 N/A HIS 152.A NE2 HIS 8.A NE2 no hydrogen 3.031 N/A ASN 154.A N THR 123.A OG1 no hydrogen 3.060 N/A ASN 154.A ND2 HIS 152.A O no hydrogen 3.231 N/A ALA 157.A N TYR 129.A OH no hydrogen 2.875 N/A LEU 167.A N ASP 164.A O no hydrogen 2.809 N/A VAL 169.A N ASP 27.A O no hydrogen 3.031 N/A LEU 171.A N PRO 168.A O no hydrogen 3.262 N/A PHE 174.A N VAL 169.A O no hydrogen 2.953 N/A THR 177.A N PHE 174.A O no hydrogen 2.935 N/A THR 177.A OG1 PHE 174.A O no hydrogen 3.417 N/A THR 178.A N PHE 175.A O no hydrogen 2.999 N/A THR 178.A OG1 PHE 175.A O no hydrogen 2.609 N/A THR 179.A OG1 THR 123.A O no hydrogen 3.284 N/A THR 179.A OG1 ASP 176.A O no hydrogen 2.819 N/A PHE 180.A N THR 177.A O no hydrogen 2.967 N/A ILE 181.A N THR 178.A O no hydrogen 3.310 N/A LYS 184.A N ILE 181.A O no hydrogen 2.864 N/A TYR 185.A N ASN 182.A O no hydrogen 3.098 N/A HIS 186.A N LEU 183.A O no hydrogen 2.905 N/A LYS 190.A N HIS 186.A O no hydrogen 2.849 N/A TYR 191.A N PHE 187.A O no hydrogen 2.742 N/A ASN 193.A N ASP 143.A OD1 no hydrogen 2.842 N/A ASN 193.A ND2 ASP 143.A OD1 no hydrogen 3.454 N/A ASN 193.A ND2 ASP 143.A OD2 no hydrogen 2.821 N/A ILE 194.A N TYR 191.A O no hydrogen 3.208 N/A LYS 195.A N ALA 147.A O no hydrogen 2.892 N/A LYS 195.A NZ GLN 146.A O no hydrogen 3.522 N/A LYS 195.A NZ ASN 193.A O no hydrogen 3.282 N/A ILE 197.A N VAL 149.A O no hydrogen 2.898 N/A ILE 198.A N TYR 231.A O no hydrogen 2.846 N/A HIS 200.A N ASP 233.A OD2 no hydrogen 2.894 N/A HIS 200.A NE2 ASP 259.A OD2 no hydrogen 3.342 N/A ALA 201.A N ASP 233.A O no hydrogen 2.941 N/A GLY 202.A N PRO 199.A O no hydrogen 3.233 N/A ALA 203.A N HIS 200.A O no hydrogen 3.098 N/A PHE 204.A N THR 178.A OG1 no hydrogen 3.337 N/A LEU 205.A N GLY 202.A O no hydrogen 2.734 N/A ILE 207.A N PHE 204.A O no hydrogen 2.930 N/A VAL 208.A N PHE 204.A O no hydrogen 3.048 N/A ASP 209.A N LEU 205.A O no hydrogen 3.166 N/A ARG 211.A N VAL 208.A O no hydrogen 2.694 N/A ILE 212.A N VAL 208.A O no hydrogen 2.930 N/A ALA 213.A N ASP 209.A O no hydrogen 2.770 N/A ALA 216.A N ILE 212.A O no hydrogen 2.815 N/A GLN 217.A N ALA 213.A O no hydrogen 3.007 N/A LYS 218.A N GLN 214.A O no hydrogen 2.903 N/A VAL 219.A N TYR 215.A O no hydrogen 2.657 N/A TYR 220.A N ALA 216.A O no hydrogen 3.047 N/A VAL 222.A N ALA 216.A O no hydrogen 2.972 N/A TYR 225.A OH ASP 210.A OD2 no hydrogen 2.627 N/A ASP 226.A N ASP 223.A O no hydrogen 2.941 N/A ASP 226.A N ASP 223.A OD1 no hydrogen 3.191 N/A VAL 227.A N ASP 223.A O no hydrogen 3.193 N/A HIS 229.A N ASP 226.A O no hydrogen 3.062 N/A HIS 229.A N VAL 227.A O no hydrogen 2.945 N/A HIS 229.A NE2 PRO 192.A O no hydrogen 3.079 N/A VAL 230.A N VAL 227.A O no hydrogen 3.056 N/A TYR 231.A N VAL 196.A O no hydrogen 2.747 N/A PHE 232.A N HIS 253.A O no hydrogen 2.962 N/A ASP 233.A N ILE 198.A O no hydrogen 3.315 N/A ALA 235.A N ASP 233.A OD2 no hydrogen 3.021 N/A VAL 238.A N GLY 236.A O no hydrogen 2.880 N/A LEU 243.A N VAL 238.A O no hydrogen 2.691 N/A THR 245.A N ARG 241.A O no hydrogen 3.199 N/A THR 245.A OG1 ARG 241.A O no hydrogen 3.226 N/A LEU 246.A N GLN 242.A O no hydrogen 3.062 N/A SER 247.A OG THR 245.A O no hydrogen 2.786 N/A LEU 248.A N LEU 246.A O no hydrogen 2.994 N/A ALA 249.A N LEU 246.A O no hydrogen 2.723 N/A GLN 250.A NE2 GLU 252.A OE1 no hydrogen 3.050 N/A HIS 253.A N GLN 250.A O no hydrogen 2.978 N/A HIS 253.A ND1 VAL 230.A O no hydrogen 2.852 N/A LEU 255.A N PHE 232.A O no hydrogen 2.650 N/A SER 258.A N ASP 4.A OD1 no hydrogen 3.062 N/A SER 258.A N HIS 6.A O no hydrogen 3.210 N/A SER 258.A OG ASP 4.A OD2 no hydrogen 2.589 N/A ASP 259.A N HIS 6.A O no hydrogen 2.617 N/A THR 263.A N ASP 259.A O no hydrogen 3.077 N/A SER 268.A N PRO 264.A O no hydrogen 2.904 N/A SER 268.A OG SER 258.A O no hydrogen 2.846 N/A ARG 269.A N LEU 265.A O no hydrogen 2.946 N/A ARG 269.A NH1 ASP 44.A O no hydrogen 2.889 N/A ARG 269.A NH1 ASN 45.A OD1 no hydrogen 2.913 N/A GLN 270.A N ASP 266.A O no hydrogen 3.070 N/A LEU 271.A N GLY 267.A O no hydrogen 2.996 N/A GLY 272.A N SER 268.A O no hydrogen 2.889 N/A HIS 273.A N ARG 269.A O no hydrogen 2.964 N/A ALA 274.A N GLN 270.A O no hydrogen 3.011 N/A LEU 275.A N LEU 271.A O no hydrogen 3.253 N/A ALA 276.A N GLY 272.A O no hydrogen 3.184 N/A THR 277.A N HIS 273.A O no hydrogen 3.016 N/A THR 277.A OG1 HIS 273.A O no hydrogen 3.358 N/A THR 278.A N ALA 274.A O no hydrogen 2.937 N/A LEU 280.A N THR 278.A OG1 no hydrogen 3.059 N/A THR 282.A N GLN 285.A OE1 no hydrogen 2.872 N/A GLN 285.A N THR 282.A OG1 no hydrogen 3.177 N/A LYS 286.A N THR 282.A O no hydrogen 3.011 N/A LYS 286.A NZ ALA 276.A O no hydrogen 2.611 N/A LYS 286.A NZ THR 278.A O no hydrogen 2.783 N/A GLN 287.A N ASN 283.A O no hydrogen 3.015 N/A ALA 288.A N GLU 284.A O no hydrogen 2.942 N/A ILE 289.A N GLN 285.A O no hydrogen 2.899 N/A PHE 290.A N LYS 286.A O no hydrogen 3.043 N/A TYR 291.A N GLN 287.A O no hydrogen 3.003 N/A ASP 292.A N GLN 287.A O no hydrogen 3.193 N/A ASN 293.A N ALA 288.A O no hydrogen 2.915 N/A ASN 293.A ND2 PRO 251.A O no hydrogen 2.887 N/A ASN 293.A ND2 LEU 254.A O no hydrogen 2.807 N/A HIS 295.A N TYR 291.A O no hydrogen 2.899 N/A ARG 296.A N ASP 292.A O no hydrogen 2.869 N/A ARG 296.A NH1 ASN 293.A OD1 no hydrogen 3.176 N/A LEU 297.A N ASN 293.A O no hydrogen 3.107 N/A LEU 298.A N ALA 294.A O no hydrogen 2.811 N/A THR 299.A N HIS 295.A O no hydrogen 2.969 N/A THR 299.A OG1 HIS 295.A O no hydrogen 3.127 N/A THR 299.A OG1 ARG 296.A O no hydrogen 3.188 N/A GLU 300.A N ARG 296.A O no hydrogen 3.222 N/A