Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2fhx_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): HIS 2.A ND1 THR 12.A OG1 no hydrogen 2.885 N/A VAL 3.A N ALA 11.A O no hydrogen 2.899 N/A LEU 5.A N LEU 9.A O no hydrogen 2.750 N/A TYR 7.A OH GLU 49.A OE1 no hydrogen 2.901 N/A ASN 8.A ND2 ASP 25.A OD1 no hydrogen 2.720 N/A THR 10.A N THR 22.A O no hydrogen 2.893 N/A ALA 11.A N VAL 3.A O no hydrogen 3.025 N/A THR 12.A N VAL 20.A O no hydrogen 2.884 N/A THR 12.A OG1 HIS 2.A ND1 no hydrogen 2.885 N/A LYS 13.A N ASP 1.A O no hydrogen 2.722 N/A ILE 14.A N VAL 18.A O no hydrogen 2.896 N/A ASP 15.A N VAL 18.A O no hydrogen 3.335 N/A SER 16.A N ASP 15.A OD1 no hydrogen 2.586 N/A VAL 18.A N ASP 15.A O no hydrogen 3.249 N/A PHE 19.A N VAL 33.A O no hydrogen 2.866 N/A VAL 20.A N THR 12.A O no hydrogen 2.820 N/A VAL 21.A N VAL 31.A O no hydrogen 2.790 N/A THR 22.A N THR 10.A O no hydrogen 2.902 N/A THR 22.A OG1 ASN 30.A OD1 no hydrogen 2.708 N/A ASP 23.A N SER 29.A O no hydrogen 3.026 N/A ARG 24.A N ASN 8.A O no hydrogen 2.960 N/A ASP 25.A N ASP 23.A OD1 no hydrogen 2.773 N/A PHE 26.A N ASP 23.A OD1 no hydrogen 3.217 N/A SER 29.A N ASP 23.A O no hydrogen 3.355 N/A ASN 30.A N GLY 218.A O no hydrogen 2.770 N/A ASN 30.A ND2 PRO 217.A O no hydrogen 3.032 N/A ASN 30.A ND2 GLY 220.A O no hydrogen 2.853 N/A VAL 31.A N VAL 21.A O no hydrogen 2.836 N/A LEU 32.A N VAL 44.A O no hydrogen 3.191 N/A VAL 33.A N PHE 19.A O no hydrogen 2.898 N/A ALA 34.A N VAL 42.A O no hydrogen 2.827 N/A LYS 35.A N ASP 17.A O no hydrogen 2.705 N/A LYS 35.A NZ MET 64.A O no hydrogen 2.667 N/A MET 36.A N THR 40A.A O no hydrogen 2.632 N/A LEU 37.A N GLU 153.A OE2 no hydrogen 2.455 N/A GLY 39.A N MET 36.A O no hydrogen 3.058 N/A VAL 41.A N LYS 68.A O no hydrogen 2.761 N/A VAL 42.A N ALA 34.A O no hydrogen 2.740 N/A ILE 43.A N VAL 70.A O no hydrogen 2.796 N/A VAL 44.A N LEU 32.A O no hydrogen 3.018 N/A SER 45.A N ILE 72.A O no hydrogen 2.961 N/A SER 46.A OG PRO 47.A O no hydrogen 2.835 N/A ASN 50.A ND2 GLU 85.A OE1 no hydrogen 2.799 N/A LEU 51.A N GLU 49.A OE2 no hydrogen 2.794 N/A GLY 52.A N GLU 49.A OE1 no hydrogen 2.931 N/A THR 53.A N GLU 49.A O no hydrogen 3.106 N/A THR 53.A OG1 GLU 49.A O no hydrogen 2.819 N/A GLN 54.A N ASN 50.A O no hydrogen 2.915 N/A THR 55.A N LEU 51.A O no hydrogen 3.135 N/A THR 55.A OG1 LEU 51.A O no hydrogen 2.838 N/A LEU 56.A N GLY 52.A O no hydrogen 2.991 N/A MET 57.A N THR 53.A O no hydrogen 2.829 N/A ASP 58.A N GLN 54.A O no hydrogen 2.845 N/A TRP 59.A N THR 55.A O no hydrogen 3.023 N/A VAL 60.A N LEU 56.A O no hydrogen 2.909 N/A ALA 61.A N MET 57.A O no hydrogen 2.889 N/A LYS 62.A N ASP 58.A O no hydrogen 2.907 N/A THR 63.A N TRP 59.A O no hydrogen 2.918 N/A THR 63.A OG1 TRP 59.A O no hydrogen 2.707 N/A MET 64.A N VAL 60.A O no hydrogen 2.855 N/A LYS 65.A N ALA 61.A O no hydrogen 3.152 N/A LYS 67.A N GLY 39.A O no hydrogen 2.987 N/A VAL 70.A N VAL 41.A O no hydrogen 2.893 N/A ALA 71.A N GLU 93.A O no hydrogen 2.849 N/A ILE 72.A N ILE 43.A O no hydrogen 2.749 N/A ASN 73.A N TRP 95.A O no hydrogen 2.740 N/A ASN 73.A ND2 ASN 84.A OD1 no hydrogen 2.962 N/A THR 74.A OG1 HIS 75.A ND1 no hydrogen 3.106 N/A HIS 75.A ND1 THR 74.A OG1 no hydrogen 3.106 N/A HIS 77.A NE2 ASP 194.A OD1 no hydrogen 2.558 N/A ASP 79.A N ASP 79.A OD2 no hydrogen 2.627 N/A GLY 80.A N SER 46.A OG no hydrogen 3.169 N/A THR 81.A N HIS 77.A O no hydrogen 2.924 N/A THR 81.A OG1 PHE 76.A O no hydrogen 3.017 N/A THR 81.A OG1 HIS 77.A O no hydrogen 3.138 N/A GLY 82.A N LEU 78.A O no hydrogen 2.739 N/A ASN 84.A N THR 81.A O no hydrogen 3.203 N/A ASN 84.A ND2 ASN 73.A OD1 no hydrogen 2.951 N/A ASN 84.A ND2 VAL 134.A O no hydrogen 2.768 N/A TYR 87.A N GLY 83.A O no hydrogen 2.775 N/A TYR 87.A OH SER 45.A O no hydrogen 3.076 N/A LYS 88.A N ASN 84.A O no hydrogen 2.818 N/A LYS 88.A NZ ASP 137.A OD1 no hydrogen 3.056 N/A LYS 89.A N GLU 85.A O no hydrogen 2.999 N/A MET 90.A N ILE 86.A O no hydrogen 2.912 N/A MET 90.A N TYR 87.A O no hydrogen 3.271 N/A GLY 91.A N LYS 88.A O no hydrogen 2.859 N/A ALA 92.A N TYR 87.A O no hydrogen 2.914 N/A GLU 93.A N VAL 69.A O no hydrogen 2.845 N/A TRP 95.A N ALA 71.A O no hydrogen 2.790 N/A SER 96.A N ASN 138.A O no hydrogen 3.029 N/A SER 96.A OG SER 97.A O no hydrogen 2.960 N/A SER 97.A OG THR 100.A OG1 no hydrogen 2.963 N/A ASP 98.A N PHE 140.A O no hydrogen 2.769 N/A LEU 99.A N ASP 98.A OD1 no hydrogen 2.922 N/A THR 100.A N SER 97.A OG no hydrogen 3.053 N/A THR 100.A OG1 SER 97.A OG no hydrogen 2.963 N/A THR 100.A OG1 ASP 167.A OD2 no hydrogen 2.696 N/A LYS 101.A N SER 97.A O no hydrogen 3.258 N/A GLN 102.A N ASP 98.A O no hydrogen 2.982 N/A GLN 102.A NE2 GLU 106.A OE1 no hydrogen 2.668 N/A LEU 103.A N LEU 99.A O no hydrogen 2.738 N/A ARG 104.A N THR 100.A O no hydrogen 2.910 N/A ARG 104.A NE ARG 104.A O no hydrogen 3.087 N/A ARG 104.A NE ASN 108.A OD1 no hydrogen 3.197 N/A ARG 104.A NH1 PHE 76.A O no hydrogen 3.005 N/A ARG 104.A NH2 ASN 108.A OD1 no hydrogen 2.878 N/A LEU 105.A N LYS 101.A O no hydrogen 3.021 N/A GLU 106.A N GLN 102.A O no hydrogen 2.910 N/A GLU 107.A N LEU 103.A O no hydrogen 2.843 N/A ASN 108.A N ARG 104.A O no hydrogen 2.942 N/A ASN 108.A ND2 PRO 133.A O no hydrogen 2.966 N/A TYR 119.A N ALA 115G.A O no hydrogen 2.948 N/A ASP 123.A N ASN 121.A OD1 no hydrogen 3.229 N/A LEU 124.A N ASN 121.A OD1 no hydrogen 3.386 N/A LYS 125.A N ASN 121.A O no hydrogen 3.090 N/A LYS 125.A NZ GLU 122.A OE1 no hydrogen 2.637 N/A LYS 125.A NZ GLU 122.A OE2 no hydrogen 3.463 N/A ARG 126.A N GLU 122.A O no hydrogen 3.016 N/A ARG 127.A N ASP 123.A O no hydrogen 3.102 N/A ARG 127.A NE ASP 123.A O no hydrogen 3.234 N/A ILE 128.A N LEU 124.A O no hydrogen 2.778 N/A LEU 129.A N LYS 125.A O no hydrogen 2.967 N/A SER 130.A N ARG 126.A O no hydrogen 2.791 N/A SER 131.A N ARG 127.A O no hydrogen 3.008 N/A SER 131.A N ILE 128.A O no hydrogen 3.113 N/A SER 131.A OG ILE 128.A O no hydrogen 2.650 N/A HIS 132.A N LEU 129.A O no hydrogen 3.256 N/A HIS 132.A NE2 ASP 111C.A OD2 no hydrogen 2.532 N/A ASP 137.A N THR 94.A OG1 no hydrogen 2.875 N/A ASN 138.A N THR 94.A O no hydrogen 2.989 N/A ASN 138.A ND2 THR 94.A O no hydrogen 2.912 N/A PHE 140.A N SER 96.A O no hydrogen 3.099 N/A LEU 142.A N ASP 98.A OD1 no hydrogen 3.118 N/A GLN 144.A NE2 GLN 144.A O no hydrogen 3.301 N/A GLY 145.A N ASP 141.A O no hydrogen 2.823 N/A GLY 145.A N LEU 142.A O no hydrogen 3.195 N/A LYS 146.A N VAL 157.A O no hydrogen 3.044 N/A PHE 148.A N VAL 155.A O no hydrogen 2.718 N/A PHE 150.A N GLU 153.A O no hydrogen 2.726 N/A SER 151.A OG PHE 150.A O no hydrogen 2.709 N/A GLU 153.A N PHE 150.A O no hydrogen 3.260 N/A VAL 155.A N PHE 148.A O no hydrogen 2.848 N/A GLU 156.A N TYR 172.A O no hydrogen 2.835 N/A VAL 157.A N LYS 146.A O no hydrogen 2.793 N/A SER 158.A N VAL 170.A O no hydrogen 2.990 N/A ALA 163.A N SER 165.A O no hydrogen 3.180 N/A SER 165.A N ASN 168.A OD1 no hydrogen 3.017 N/A SER 165.A OG ASP 167.A OD1 no hydrogen 2.673 N/A ASN 168.A ND2 GLY 161.A O no hydrogen 2.930 N/A ASN 168.A ND2 ASN 168.A O no hydrogen 2.829 N/A VAL 169.A N THR 74.A O no hydrogen 2.983 N/A VAL 170.A N SER 158.A O no hydrogen 2.902 N/A VAL 171.A N PHE 180.A O no hydrogen 3.117 N/A TYR 172.A N GLU 156.A O no hydrogen 2.724 N/A PHE 173.A N LEU 178.A O no hydrogen 2.792 N/A LYS 176.A NZ SER 16.A O no hydrogen 2.793 N/A LYS 177.A N PRO 174.A O no hydrogen 3.308 N/A LYS 177.A NZ ASP 211.A OD2 no hydrogen 2.669 N/A LEU 178.A N PHE 173.A O no hydrogen 3.105 N/A LEU 179.A N ILE 214.A O no hydrogen 3.002 N/A PHE 180.A N VAL 171.A O no hydrogen 2.861 N/A GLY 181.A N ILE 216.A O no hydrogen 2.849 N/A GLY 182.A N ILE 216.A O no hydrogen 3.213 N/A ILE 184.A N GLY 182.A O no hydrogen 3.051 N/A LYS 185.A N THR 231.A OG1 no hydrogen 2.960 N/A ALA 195.A N LEU 192.A O no hydrogen 2.976 N/A ASN 196.A N ALA 163.A O no hydrogen 2.776 N/A ALA 199.A N ASN 196.A O no hydrogen 3.123 N/A ALA 199.A N ASN 196.A OD1 no hydrogen 3.033 N/A TRP 200.A N VAL 197.A O no hydrogen 3.147 N/A TRP 200.A NE1 MET 183.A O no hydrogen 2.987 N/A SER 203.A N ALA 199.A O no hydrogen 2.960 N/A SER 203.A OG PRO 162.A O no hydrogen 2.691 N/A SER 203.A OG ALA 199.A O no hydrogen 2.970 N/A ALA 204.A N TRP 200.A O no hydrogen 2.795 N/A ARG 205.A N PRO 201.A O no hydrogen 2.937 N/A ARG 205.A NH1 GLU 236.A OE2 no hydrogen 2.693 N/A ARG 205.A NH2 ASP 202.A OD1 no hydrogen 2.583 N/A ARG 206.A N ASP 202.A O no hydrogen 3.207 N/A ARG 206.A N SER 203.A O no hydrogen 3.286 N/A ARG 206.A NH1 PRO 160.A O no hydrogen 2.840 N/A LEU 207.A N ALA 204.A O no hydrogen 2.935 N/A LYS 208.A N ARG 205.A O no hydrogen 3.171 N/A LYS 209.A N ARG 206.A O no hydrogen 3.363 N/A PHE 210.A N LEU 207.A O no hydrogen 3.182 N/A LYS 213.A N LYS 177.A O no hydrogen 2.760 N/A ILE 214.A N LYS 177.A O no hydrogen 3.306 N/A VAL 215.A N GLY 223.A O no hydrogen 2.753 N/A ILE 216.A N LEU 179.A O no hydrogen 2.803 N/A GLY 220.A N SER 28.A O no hydrogen 2.863 N/A GLY 223.A N VAL 215.A O no hydrogen 3.254 N/A GLY 224.A N GLU 226.A OE2 no hydrogen 2.655 N/A GLU 226.A N GLU 226.A OE1 no hydrogen 2.930 N/A MET 227.A N GLY 224.A O no hydrogen 3.157 N/A VAL 228.A N PRO 225.A O no hydrogen 3.117 N/A ASN 229.A ND2 PRO 225.A O no hydrogen 3.030 N/A LYS 230.A N GLU 226.A O no hydrogen 2.894 N/A THR 231.A N MET 227.A O no hydrogen 3.096 N/A THR 231.A OG1 MET 227.A O no hydrogen 2.921 N/A ILE 232.A N VAL 228.A O no hydrogen 3.043 N/A LYS 233.A N ASN 229.A O no hydrogen 3.340 N/A VAL 234.A N LYS 230.A O no hydrogen 3.021 N/A ALA 235.A N THR 231.A O no hydrogen 2.849 N/A GLU 236.A N ILE 232.A O no hydrogen 2.800 N/A LYS 237.A N LYS 233.A O no hydrogen 2.891 N/A LYS 237.A NZ GLU 241.A OE1 no hydrogen 3.466 N/A ALA 238.A N VAL 234.A O no hydrogen 3.098 N/A VAL 239.A N ALA 235.A O no hydrogen 2.899 N/A GLY 240.A N GLU 236.A O no hydrogen 2.880 N/A GLU 241.A N LYS 237.A O no hydrogen 2.839 N/A MET 242.A N ALA 238.A O no hydrogen 2.891 N/A ARG 243.A NE GLY 240.A O no hydrogen 3.192 N/A ARG 243.A NH2 GLY 240.A O no hydrogen 2.926 N/A LEU 244.A N VAL 239.A O no hydrogen 3.083 N/A THR 40A.A N ASP 38.A OD1 no hydrogen 3.153 N/A THR 40A.A OG1 ASP 38.A OD1 no hydrogen 3.377 N/A LYS 109A.A N LEU 105.A O no hydrogen 2.981 N/A LYS 110B.A N GLU 106.A O no hydrogen 2.961 N/A ASP 111C.A N GLU 107.A O no hydrogen 3.001 N/A ARG 112D.A N ASN 108.A O no hydrogen 2.798 N/A ILE 113E.A N LYS 109A.A O no hydrogen 2.896 N/A LYS 114F.A N LYS 110B.A O no hydrogen 3.104 N/A ALA 115G.A N ASP 111C.A O no hydrogen 2.878 N/A ALA 116H.A N ARG 112D.A O no hydrogen 3.062 N/A GLU 117I.A N ILE 113E.A O no hydrogen 3.271 N/A PHE 118J.A N LYS 114F.A O no hydrogen 2.861 N/A