Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2fik_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 1.A N MET 92.A O no hydrogen 3.366 N/A THR 2.A OG1 GLU 91.A OE1 no hydrogen 2.090 N/A PHE 3.A N CYS 90.A O no hydrogen 2.760 N/A ARG 4.A N TRP 24.A O no hydrogen 2.887 N/A CYS 5.A N ALA 88.A O no hydrogen 2.712 N/A LEU 6.A N VAL 22.A O no hydrogen 2.816 N/A GLN 7.A N LEU 86.A O no hydrogen 2.863 N/A GLN 7.A NE2 SER 9.A OG no hydrogen 2.906 N/A MET 8.A N ASP 20.A O no hydrogen 2.826 N/A SER 9.A N ILE 84.A O no hydrogen 2.870 N/A SER 10.A N ARG 18.A O no hydrogen 2.949 N/A SER 10.A OG GLU 83.A OE1 no hydrogen 2.510 N/A SER 10.A OG GLU 83.A OE2 no hydrogen 3.176 N/A PHE 11.A N ILE 82.A O no hydrogen 2.804 N/A ALA 12.A N TRP 16.A O no hydrogen 2.938 N/A ASN 13.A N TRP 16.A O no hydrogen 3.500 N/A SER 15.A N ASN 13.A OD1 no hydrogen 3.170 N/A TRP 16.A N ASN 13.A O no hydrogen 3.426 N/A ARG 18.A N SER 10.A O no hydrogen 3.010 N/A ARG 18.A NE ASP 20.A OD1 no hydrogen 2.938 N/A ARG 18.A NH1 ASP 36.A OD1 no hydrogen 3.308 N/A ARG 18.A NH2 ASP 20.A OD1 no hydrogen 3.357 N/A ARG 18.A NH2 ASP 20.A OD2 no hydrogen 2.791 N/A THR 19.A N ASN 35.A OD1 no hydrogen 2.936 N/A ASP 20.A N MET 8.A O no hydrogen 3.001 N/A SER 21.A N TRP 33.A O no hydrogen 2.957 N/A VAL 22.A N LEU 6.A O no hydrogen 3.021 N/A VAL 23.A N HIS 31.A O no hydrogen 3.033 N/A TRP 24.A N ARG 4.A O no hydrogen 2.864 N/A LEU 25.A N LEU 28.A O no hydrogen 2.915 N/A GLY 26.A N THR 2.A O no hydrogen 2.880 N/A LEU 28.A N LEU 25.A O no hydrogen 3.159 N/A GLN 29.A NE2 HIS 31.A O no hydrogen 3.192 N/A THR 30.A N VAL 23.A O no hydrogen 2.819 N/A THR 30.A OG1 VAL 23.A O no hydrogen 3.325 N/A THR 30.A OG1 HIS 31.A ND1 no hydrogen 2.830 N/A HIS 31.A N VAL 23.A O no hydrogen 3.437 N/A HIS 31.A ND1 THR 30.A OG1 no hydrogen 2.830 N/A HIS 31.A NE2 SER 47.A O no hydrogen 2.881 N/A ARG 32.A N SER 41.A O no hydrogen 3.014 N/A TRP 33.A N SER 21.A O no hydrogen 2.794 N/A TRP 33.A NE1 SER 37.A O no hydrogen 3.011 N/A SER 34.A OG ASP 36.A OD2 no hydrogen 2.759 N/A ASN 35.A N ASP 20.A OD2 no hydrogen 2.816 N/A ASP 36.A N SER 34.A OG no hydrogen 3.135 N/A SER 37.A N SER 34.A O no hydrogen 3.033 N/A SER 37.A OG THR 39.A O no hydrogen 2.760 N/A THR 39.A N SER 37.A OG no hydrogen 3.292 N/A ILE 40.A N GLN 60.A OE1 no hydrogen 2.968 N/A SER 41.A N ARG 32.A O no hydrogen 2.785 N/A THR 43.A N THR 30.A O no hydrogen 3.126 N/A THR 43.A OG1 GLN 29.A O no hydrogen 2.804 N/A LYS 44.A N SER 47.A OG no hydrogen 2.919 N/A LYS 44.A NZ GLN 29.A O no hydrogen 2.978 N/A LYS 44.A NZ THR 43.A O no hydrogen 3.565 N/A LYS 44.A NZ GLU 229.A OE1 no hydrogen 3.507 N/A LYS 44.A NZ GLU 229.A OE2 no hydrogen 2.595 N/A TRP 46.A NE1 ASP 168.A OD2 no hydrogen 2.795 N/A SER 47.A N LYS 44.A O no hydrogen 3.505 N/A SER 47.A OG THR 30.A O no hydrogen 2.608 N/A SER 47.A OG LYS 44.A O no hydrogen 3.145 N/A GLN 48.A NE2 LEU 51.A O no hydrogen 2.790 N/A GLN 48.A NE2 ASN 53.A OD1 no hydrogen 2.883 N/A GLY 49.A N TRP 46.A O no hydrogen 2.908 N/A LEU 51.A N GLN 48.A O no hydrogen 3.133 N/A SER 52.A N GLN 55.A OE1 no hydrogen 2.935 N/A SER 52.A OG GLN 55.A OE1 no hydrogen 3.208 N/A GLN 54.A NE2 SER 52.A OG no hydrogen 2.870 N/A GLN 55.A N SER 52.A OG no hydrogen 3.035 N/A TRP 56.A N SER 52.A O no hydrogen 2.877 N/A GLU 57.A N ASN 53.A O no hydrogen 2.927 N/A LYS 58.A N GLN 54.A O no hydrogen 3.052 N/A LEU 59.A N GLN 55.A O no hydrogen 3.028 N/A GLN 60.A N TRP 56.A O no hydrogen 2.813 N/A HIS 61.A N GLU 57.A O no hydrogen 2.894 N/A MET 62.A N LYS 58.A O no hydrogen 3.126 N/A PHE 63.A N LEU 59.A O no hydrogen 3.158 N/A GLN 64.A N GLN 60.A O no hydrogen 2.876 N/A GLN 64.A NE2 ALA 38.A O no hydrogen 2.735 N/A VAL 65.A N HIS 61.A O no hydrogen 3.065 N/A TYR 66.A N MET 62.A O no hydrogen 2.941 N/A TYR 66.A OH GLN 7.A OE1 no hydrogen 2.505 N/A ARG 67.A N PHE 63.A O no hydrogen 2.863 N/A ARG 67.A NH1 SER 34.A O no hydrogen 2.998 N/A ARG 67.A NH1 SER 37.A O no hydrogen 3.293 N/A ARG 67.A NH2 SER 37.A O no hydrogen 2.944 N/A VAL 68.A N GLN 64.A O no hydrogen 3.456 N/A SER 69.A N VAL 65.A O no hydrogen 2.925 N/A SER 69.A OG VAL 65.A O no hydrogen 3.165 N/A PHE 70.A N TYR 66.A O no hydrogen 2.738 N/A THR 71.A N ARG 67.A O no hydrogen 3.341 N/A THR 71.A OG1 ARG 67.A O no hydrogen 2.902 N/A ARG 72.A N VAL 68.A O no hydrogen 3.158 N/A ASP 73.A N SER 69.A O no hydrogen 2.815 N/A ILE 74.A N PHE 70.A O no hydrogen 3.030 N/A GLN 75.A N THR 71.A O no hydrogen 3.077 N/A GLN 75.A NE2 ASN 13.A O no hydrogen 3.136 N/A GLU 76.A N ARG 72.A O no hydrogen 2.955 N/A LEU 77.A N ASP 73.A O no hydrogen 2.913 N/A VAL 78.A N ILE 74.A O no hydrogen 2.959 N/A LYS 79.A N GLU 76.A O no hydrogen 3.204 N/A TYR 80.A OH GLN 75.A OE1 no hydrogen 2.522 N/A ILE 82.A N PHE 11.A O no hydrogen 2.927 N/A GLU 83.A N GLN 107.A OE1 no hydrogen 2.791 N/A ILE 84.A N SER 9.A O no hydrogen 2.875 N/A GLN 85.A N ALA 105.A O no hydrogen 2.978 N/A LEU 86.A N GLN 7.A O no hydrogen 2.980 N/A SER 87.A N HIS 103.A O no hydrogen 2.917 N/A ALA 88.A N CYS 5.A O no hydrogen 3.067 N/A GLY 89.A N PHE 101.A O no hydrogen 3.028 N/A CYS 90.A N PHE 3.A O no hydrogen 3.021 N/A GLU 91.A N GLU 99.A O no hydrogen 2.811 N/A MET 92.A N TYR 1.A O no hydrogen 2.771 N/A TYR 93.A N ALA 97.A O no hydrogen 2.830 N/A GLU 99.A N GLU 91.A O no hydrogen 2.962 N/A SER 100.A OG LEU 150.A O no hydrogen 2.441 N/A PHE 101.A N GLY 89.A O no hydrogen 2.865 N/A HIS 103.A N SER 87.A O no hydrogen 2.815 N/A VAL 104.A N VAL 112.A O no hydrogen 2.750 N/A ALA 105.A N GLN 85.A O no hydrogen 2.870 N/A PHE 106.A N LYS 109.A O no hydrogen 2.769 N/A GLN 107.A N GLU 83.A O no hydrogen 2.848 N/A GLN 107.A NE2 PRO 81.A O no hydrogen 2.980 N/A LYS 109.A N PHE 106.A O no hydrogen 3.116 N/A VAL 111.A N VAL 104.A O no hydrogen 2.927 N/A VAL 112.A N VAL 104.A O no hydrogen 3.320 N/A ARG 113.A N GLN 120.A O no hydrogen 2.943 N/A PHE 114.A N LEU 102.A O no hydrogen 3.015 N/A TRP 115.A N SER 118.A O no hydrogen 2.884 N/A SER 118.A N TRP 115.A O no hydrogen 3.286 N/A TRP 119.A N ASN 137.A OD1 no hydrogen 2.839 N/A GLN 120.A N ARG 113.A O no hydrogen 2.798 N/A THR 121.A OG1 ASP 130.A OD1 no hydrogen 3.558 N/A VAL 122.A N VAL 111.A O no hydrogen 2.913 N/A ALA 125.A N VAL 122.A O no hydrogen 2.984 N/A LEU 129.A N PRO 126.A O no hydrogen 3.237 N/A ASP 130.A N SER 127.A O no hydrogen 3.126 N/A ILE 133.A N LEU 129.A O no hydrogen 3.055 N/A LYS 134.A N ASP 130.A O no hydrogen 3.007 N/A LYS 134.A NZ LYS 134.A O no hydrogen 2.952 N/A VAL 135.A N LEU 131.A O no hydrogen 2.935 N/A LEU 136.A N PRO 132.A O no hydrogen 2.884 N/A ASN 137.A N ILE 133.A O no hydrogen 2.970 N/A ASN 137.A ND2 TRP 119.A O no hydrogen 2.866 N/A ALA 138.A N VAL 135.A O no hydrogen 2.921 N/A ASP 139.A N LEU 136.A O no hydrogen 3.036 N/A THR 142.A N ASP 139.A OD1 no hydrogen 2.993 N/A THR 142.A OG1 ASP 139.A OD2 no hydrogen 2.881 N/A SER 143.A N ASP 139.A O no hydrogen 3.129 N/A SER 143.A OG THR 117.A O no hydrogen 2.821 N/A ALA 144.A N GLN 140.A O no hydrogen 2.838 N/A THR 145.A N GLY 141.A O no hydrogen 3.070 N/A THR 145.A OG1 GLY 141.A O no hydrogen 2.919 N/A VAL 146.A N THR 142.A O no hydrogen 2.915 N/A GLN 147.A N SER 143.A O no hydrogen 2.968 N/A GLN 147.A NE2 SER 143.A O no hydrogen 3.503 N/A GLN 147.A NE2 SER 143.A OG no hydrogen 3.164 N/A MET 148.A N ALA 144.A O no hydrogen 3.039 N/A LEU 149.A N THR 145.A O no hydrogen 2.859 N/A LEU 150.A N VAL 146.A O no hydrogen 2.875 N/A ASN 151.A N GLN 147.A O no hydrogen 2.827 N/A ASP 152.A N MET 148.A O no hydrogen 2.894 N/A THR 153.A N MET 148.A O no hydrogen 2.964 N/A THR 153.A OG1 MET 148.A O no hydrogen 3.454 N/A CYS 154.A N LEU 149.A O no hydrogen 2.726 N/A LEU 156.A N ASP 152.A O no hydrogen 3.248 N/A PHE 157.A N THR 153.A O no hydrogen 2.863 N/A VAL 158.A N CYS 154.A O no hydrogen 2.982 N/A ARG 159.A N PRO 155.A O no hydrogen 2.964 N/A GLY 160.A N LEU 156.A O no hydrogen 3.281 N/A LEU 161.A N PHE 157.A O no hydrogen 3.022 N/A LEU 162.A N VAL 158.A O no hydrogen 2.905 N/A GLU 163.A N ARG 159.A O no hydrogen 3.272 N/A ALA 164.A N GLY 160.A O no hydrogen 2.882 N/A GLY 165.A N LEU 161.A O no hydrogen 2.706 N/A LYS 166.A N GLU 163.A O no hydrogen 3.211 N/A LYS 166.A NZ GLU 170.A OE2 no hydrogen 3.535 N/A ASP 168.A N GLY 165.A O no hydrogen 3.060 N/A LEU 169.A N GLY 165.A O no hydrogen 2.882 N/A GLU 170.A N LYS 166.A O no hydrogen 2.824 N/A LYS 171.A N ASP 168.A O no hydrogen 3.166 N/A LYS 171.A NZ GLU 229.A O no hydrogen 2.875 N/A GLU 173.A N TYR 200.A O no hydrogen 2.827 N/A VAL 176.A N SER 197.A O no hydrogen 2.925 N/A TRP 178.A N HIS 195.A O no hydrogen 2.950 N/A SER 180.A N VAL 193.A O no hydrogen 2.960 N/A SER 180.A OG HIS 195.A NE2 no hydrogen 2.785 N/A VAL 182.A N GLN 191.A O no hydrogen 3.078 N/A SER 184.A N HIS 189.A O no hydrogen 3.027 N/A SER 184.A OG ASP 238.A OD2 no hydrogen 3.377 N/A HIS 189.A N ALA 186.A O no hydrogen 2.994 N/A ARG 190.A N VAL 239.A O no hydrogen 2.936 N/A ARG 190.A NH1 SER 181.A OG no hydrogen 2.511 N/A ARG 190.A NH2 SER 181.A OG no hydrogen 2.856 N/A GLN 191.A N VAL 182.A O no hydrogen 2.847 N/A LEU 192.A N LEU 237.A O no hydrogen 2.805 N/A VAL 193.A N SER 180.A O no hydrogen 2.756 N/A CYS 194.A N ALA 235.A O no hydrogen 2.851 N/A HIS 195.A N TRP 178.A O no hydrogen 2.814 N/A HIS 195.A ND1 TYR 232.A OH no hydrogen 2.953 N/A HIS 195.A NE2 SER 180.A OG no hydrogen 2.785 N/A VAL 196.A N LEU 233.A O no hydrogen 2.835 N/A SER 197.A N VAL 176.A O no hydrogen 2.844 N/A GLY 198.A N TRP 231.A O no hydrogen 2.799 N/A TYR 200.A N GLU 173.A O no hydrogen 3.035 N/A TYR 200.A OH ASP 27.A OD1 no hydrogen 2.536 N/A TRP 205.A N LYS 252.A O no hydrogen 3.044 N/A MET 207.A N ARG 250.A O no hydrogen 3.009 N/A TRP 208.A N THR 218.A OG1 no hydrogen 3.001 N/A TRP 208.A NE1 ALA 235.A O no hydrogen 3.189 N/A MET 209.A N ALA 248.A O no hydrogen 2.709 N/A ARG 210.A N GLN 213.A O no hydrogen 2.934 N/A ARG 210.A NH1 GLU 243.A O no hydrogen 2.967 N/A ARG 210.A NH2 GLU 243.A O no hydrogen 2.438 N/A GLN 213.A N ARG 210.A O no hydrogen 2.982 N/A GLN 215.A N TRP 208.A O no hydrogen 2.776 N/A THR 218.A N GLN 215.A O no hydrogen 2.961 N/A THR 218.A OG1 GLN 215.A O no hydrogen 2.797 N/A HIS 219.A N THR 236.A O no hydrogen 2.871 N/A GLY 221.A N GLN 234.A O no hydrogen 2.733 N/A LEU 224.A N TYR 232.A O no hydrogen 2.834 N/A ASN 226.A N THR 230.A O no hydrogen 2.929 N/A ASN 226.A ND2 SER 197.A OG no hydrogen 3.067 N/A ASN 226.A ND2 THR 230.A OG1 no hydrogen 3.021 N/A THR 230.A OG1 ASP 228.A OD1 no hydrogen 2.665 N/A TRP 231.A N PHE 199.A O no hydrogen 2.856 N/A TRP 231.A NE1 ASP 27.A OD2 no hydrogen 2.944 N/A TYR 232.A N LEU 224.A O no hydrogen 2.762 N/A TYR 232.A OH HIS 195.A ND1 no hydrogen 2.953 N/A TYR 232.A OH GLN 234.A OE1 no hydrogen 2.803 N/A LEU 233.A N VAL 196.A O no hydrogen 2.921 N/A ALA 235.A N CYS 194.A O no hydrogen 2.917 N/A THR 236.A N HIS 219.A O no hydrogen 2.959 N/A LEU 237.A N LEU 192.A O no hydrogen 2.913 N/A VAL 239.A N ARG 190.A O no hydrogen 2.880 N/A ALA 241.A N GLY 188.A O no hydrogen 2.823 N/A GLU 243.A N GLU 240.A O no hydrogen 2.833 N/A LEU 247.A N GLU 244.A O no hydrogen 3.374 N/A ALA 248.A N MET 209.A O no hydrogen 2.931 N/A CYS 249.A N LEU 263.A O no hydrogen 2.789 N/A ARG 250.A N MET 207.A O no hydrogen 2.872 N/A ARG 250.A NE ASP 260.A OD2 no hydrogen 2.589 N/A ARG 250.A NH2 ASP 260.A OD2 no hydrogen 2.952 N/A VAL 251.A N ILE 261.A O no hydrogen 2.832 N/A LYS 252.A N TRP 205.A O no hydrogen 2.889 N/A LYS 252.A NZ ASP 260.A OD2 no hydrogen 2.613 N/A HIS 253.A ND1 SER 255.A OG no hydrogen 2.817 N/A HIS 253.A NE2 PRO 201.A O no hydrogen 2.694 N/A SER 254.A OG GLN 172.A OE1 no hydrogen 2.661 N/A SER 255.A N HIS 253.A ND1 no hydrogen 3.139 N/A SER 255.A OG GLU 173.A O no hydrogen 3.414 N/A SER 255.A OG HIS 253.A ND1 no hydrogen 2.817 N/A LEU 256.A N HIS 253.A O no hydrogen 3.007 N/A GLN 259.A N LEU 256.A O no hydrogen 3.166 N/A GLN 259.A NE2 ASP 260.A O no hydrogen 2.913 N/A ILE 261.A N VAL 251.A O no hydrogen 3.001 N/A LEU 263.A N CYS 249.A O no hydrogen 2.940 N/A TRP 265.A N LEU 247.A O no hydrogen 3.007 N/A TRP 265.A NE1 GLU 244.A OE2 no hydrogen 2.915 N/A