Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2g4c_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): CYS 8.A N LEU 4.A O no hydrogen 2.743 N/A CYS 8.A SG LEU 4.A O no hydrogen 3.302 N/A GLN 9.A N GLU 6.A O no hydrogen 2.940 N/A ARG 10.A N GLU 6.A O no hydrogen 2.990 N/A ARG 11.A N ILE 7.A O no hydrogen 2.780 N/A ARG 11.A NE GLU 346.A OE2 no hydrogen 2.802 N/A ARG 11.A NH2 GLU 346.A OE2 no hydrogen 3.512 N/A HIS 12.A N GLN 9.A O no hydrogen 3.206 N/A PHE 13.A N CYS 8.A O no hydrogen 2.797 N/A LEU 14.A N CYS 8.A O no hydrogen 2.917 N/A SER 17.A N GLN 20.A OE1 no hydrogen 3.136 N/A SER 17.A OG GLN 20.A OE1 no hydrogen 3.334 N/A SER 22.A OG GLN 19.A O no hydrogen 2.652 N/A SER 25.A OG GLN 20.A O no hydrogen 3.236 N/A LEU 26.A N SER 22.A O no hydrogen 2.778 N/A LEU 27.A N ARG 23.A O no hydrogen 3.261 N/A SER 28.A N ASP 24.A O no hydrogen 3.173 N/A SER 28.A OG ASP 24.A O no hydrogen 3.327 N/A CYS 30.A N SER 25.A O no hydrogen 3.041 N/A CYS 30.A SG SER 28.A O no hydrogen 3.933 N/A CYS 30.A SG SER 28.A OG no hydrogen 3.063 N/A CYS 30.A SG ILE 156.A O no hydrogen 3.730 N/A GLY 35.A N PHE 13.A O no hydrogen 2.912 N/A LEU 37.A N HIS 12.A O no hydrogen 3.167 N/A VAL 39.A N GLY 35.A O no hydrogen 2.856 N/A GLU 40.A N PRO 36.A O no hydrogen 2.881 N/A LEU 41.A N LEU 37.A O no hydrogen 2.677 N/A ARG 42.A N GLY 38.A O no hydrogen 2.827 N/A ARG 42.A NH1 ASP 268.A OD1 no hydrogen 2.654 N/A ARG 42.A NH1 ASP 268.A OD2 no hydrogen 3.399 N/A LYS 43.A N VAL 39.A O no hydrogen 2.869 N/A ASN 44.A N GLU 40.A O no hydrogen 2.951 N/A LEU 45.A N LEU 41.A O no hydrogen 3.112 N/A ALA 46.A N ARG 42.A O no hydrogen 2.667 N/A ALA 47.A N LYS 43.A O no hydrogen 2.883 N/A GLU 48.A N ASN 44.A O no hydrogen 2.595 N/A TRP 49.A N LEU 45.A O no hydrogen 2.902 N/A TRP 50.A N ALA 46.A O no hydrogen 3.065 N/A THR 51.A N ALA 47.A O no hydrogen 3.028 N/A THR 51.A OG1 ALA 47.A O no hydrogen 2.677 N/A THR 51.A OG1 GLU 48.A O no hydrogen 3.208 N/A SER 52.A N GLU 48.A O no hydrogen 2.900 N/A VAL 53.A N TRP 49.A O no hydrogen 3.222 N/A VAL 54.A N TRP 50.A O no hydrogen 2.963 N/A VAL 55.A N TRP 50.A O no hydrogen 3.166 N/A PHE 56.A N THR 51.A O no hydrogen 3.298 N/A GLU 58.A N PHE 56.A O no hydrogen 3.214 N/A GLN 59.A N ARG 57.A O no hydrogen 2.736 N/A PHE 61.A N GLY 142.A O no hydrogen 2.937 N/A VAL 63.A N ALA 144.A O no hydrogen 3.259 N/A ALA 65.A N GLN 145.A OE1 no hydrogen 3.316 N/A LYS 69.A N LYS 115.A O no hydrogen 2.727 N/A LYS 69.A NZ PRO 70.A O no hydrogen 3.467 N/A ARG 81.A NE LEU 110.A O no hydrogen 3.066 N/A ARG 81.A NH2 GLY 76.A O no hydrogen 2.687 N/A ARG 81.A NH2 LEU 110.A O no hydrogen 3.375 N/A LEU 82.A N GLY 114.A O no hydrogen 3.151 N/A THR 87.A OG1 SER 84.A O no hydrogen 2.446 N/A LEU 88.A N ALA 85.A O no hydrogen 2.914 N/A ARG 89.A N ALA 85.A O no hydrogen 3.480 N/A ILE 91.A N LEU 88.A O no hydrogen 2.878 N/A LEU 92.A N LEU 88.A O no hydrogen 3.123 N/A LEU 92.A N ARG 89.A O no hydrogen 2.550 N/A LYS 95.A N GLN 93.A O no hydrogen 2.380 N/A SER 98.A OG LYS 95.A O no hydrogen 2.592 N/A LYS 99.A N LEU 97.A O no hydrogen 2.360 N/A GLN 101.A N LEU 97.A O no hydrogen 3.073 N/A VAL 103.A N GLU 100.A O no hydrogen 3.411 N/A THR 104.A OG1 GLU 100.A O no hydrogen 3.046 N/A PHE 105.A N GLN 101.A O no hydrogen 3.200 N/A GLU 107.A N THR 104.A O no hydrogen 3.103 N/A ASN 108.A N PHE 105.A O no hydrogen 2.461 N/A VAL 109.A N PHE 105.A O no hydrogen 3.296 N/A THR 112.A N ASN 108.A O no hydrogen 2.594 N/A THR 112.A N VAL 109.A O no hydrogen 2.722 N/A THR 112.A OG1 ASN 108.A O no hydrogen 2.599 N/A SER 113.A N VAL 109.A O no hydrogen 2.867 N/A LYS 115.A N LYS 69.A O no hydrogen 3.111 N/A LYS 115.A NZ ASP 77.A OD2 no hydrogen 3.239 N/A ARG 117.A N HIS 67.A O no hydrogen 2.993 N/A ARG 117.A NE LEU 66.A O no hydrogen 2.919 N/A ARG 117.A NH1 VAL 148.A O no hydrogen 2.594 N/A ARG 117.A NH2 ALA 65.A O no hydrogen 3.528 N/A ARG 117.A NH2 LEU 66.A O no hydrogen 3.314 N/A ALA 124.A N LEU 120.A O no hydrogen 3.214 N/A LEU 125.A N LEU 121.A O no hydrogen 2.953 N/A GLU 126.A N HIS 122.A O no hydrogen 2.865 N/A HIS 127.A N ALA 124.A O no hydrogen 2.832 N/A TYR 128.A N LEU 125.A O no hydrogen 2.957 N/A CYS 131.A N HIS 127.A O no hydrogen 2.812 N/A LEU 132.A N VAL 129.A O no hydrogen 2.805 N/A LYS 137.A N VAL 135.A O no hydrogen 2.244 N/A ARG 138.A N VAL 135.A O no hydrogen 2.773 N/A LEU 139.A N ARG 250.A O no hydrogen 3.372 N/A GLY 142.A N GLN 59.A O no hydrogen 3.129 N/A LEU 143.A N VAL 165.A O no hydrogen 3.111 N/A ALA 144.A N PHE 61.A O no hydrogen 2.877 N/A GLN 145.A N SER 163.A O no hydrogen 2.670 N/A GLY 147.A N GLU 161.A O no hydrogen 2.634 N/A CYS 149.A N LYS 159.A O no hydrogen 2.594 N/A CYS 149.A SG GLU 161.A OE2 no hydrogen 3.315 N/A PHE 150.A N ARG 117.A O no hydrogen 3.205 N/A HIS 151.A N GLY 157.A O no hydrogen 2.910 N/A HIS 151.A NE2 GLU 118.A O no hydrogen 2.835 N/A VAL 153.A N SER 155.A O no hydrogen 3.225 N/A GLY 157.A N HIS 151.A O no hydrogen 2.729 N/A GLU 158.A N GLY 29.A O no hydrogen 3.028 N/A LYS 159.A N CYS 149.A O no hydrogen 2.943 N/A LYS 159.A NZ LEU 27.A O no hydrogen 2.959 N/A LYS 159.A NZ ASP 266.A OD2 no hydrogen 3.125 N/A THR 160.A N ASP 268.A OD2 no hydrogen 2.736 N/A GLU 161.A N GLY 147.A O no hydrogen 2.571 N/A ALA 162.A N GLY 265.A O no hydrogen 3.049 N/A SER 163.A N GLN 145.A O no hydrogen 2.571 N/A LEU 164.A N VAL 263.A O no hydrogen 3.156 N/A VAL 165.A N LEU 143.A O no hydrogen 3.231 N/A TRP 166.A N LEU 261.A O no hydrogen 3.077 N/A PHE 167.A N TYR 141.A O no hydrogen 3.143 N/A THR 168.A N CYS 259.A O no hydrogen 3.148 N/A THR 168.A OG1 PRO 169.A O no hydrogen 3.352 N/A ARG 171.A NH2 ASP 251.A OD1 no hydrogen 3.131 N/A SER 173.A N PRO 169.A O no hydrogen 2.708 N/A TRP 176.A N THR 172.A O no hydrogen 2.677 N/A LEU 177.A N SER 173.A O no hydrogen 3.233 N/A ASP 178.A N GLN 175.A O no hydrogen 2.822 N/A PHE 179.A N GLN 175.A O no hydrogen 3.255 N/A TRP 180.A N TRP 176.A O no hydrogen 2.872 N/A LEU 181.A N LEU 177.A O no hydrogen 3.129 N/A ARG 182.A N ASP 178.A O no hydrogen 3.063 N/A HIS 183.A N PHE 179.A O no hydrogen 2.785 N/A HIS 183.A NE2 SER 52.A O no hydrogen 3.238 N/A ARG 184.A N TRP 180.A O no hydrogen 2.746 N/A ARG 184.A NE GLU 226.A OE1 no hydrogen 2.615 N/A ARG 184.A NE GLU 226.A OE2 no hydrogen 2.680 N/A ARG 184.A NH2 GLU 226.A OE1 no hydrogen 2.869 N/A LEU 185.A N LEU 181.A O no hydrogen 2.792 N/A GLN 186.A N ARG 182.A O no hydrogen 2.660 N/A TRP 187.A N HIS 183.A O no hydrogen 2.828 N/A TRP 188.A N ARG 184.A O no hydrogen 3.100 N/A TRP 188.A NE1 GLU 226.A OE1 no hydrogen 2.659 N/A ARG 189.A N LEU 185.A O no hydrogen 3.439 N/A ARG 189.A NE PHE 198.A O no hydrogen 3.026 N/A ARG 189.A NH2 PHE 198.A O no hydrogen 2.768 N/A LYS 190.A N GLN 186.A O no hydrogen 3.224 N/A ALA 192.A N ARG 189.A O no hydrogen 2.797 N/A MET 193.A N ASP 277.A OD2 no hydrogen 2.771 N/A SER 194.A N ASP 277.A OD1 no hydrogen 3.375 N/A SER 194.A OG ASP 277.A OD1 no hydrogen 3.414 N/A ASN 197.A N SER 194.A O no hydrogen 2.741 N/A SER 199.A N TYR 215.A O no hydrogen 2.985 N/A SER 201.A OG LYS 213.A O no hydrogen 3.400 N/A CYS 203.A SG GLY 211.A O no hydrogen 2.818 N/A GLU 206.A N GLY 208.A O no hydrogen 3.320 N/A GLY 211.A N CYS 203.A O no hydrogen 2.911 N/A LYS 213.A N SER 201.A O no hydrogen 3.240 N/A LEU 214.A N GLU 226.A O no hydrogen 2.562 N/A TYR 215.A N SER 199.A O no hydrogen 2.663 N/A TYR 216.A N GLU 223.A O no hydrogen 2.921 N/A ASN 217.A N ASN 197.A O no hydrogen 2.757 N/A GLY 221.A N PHE 218.A O no hydrogen 2.532 N/A GLU 223.A N TYR 216.A O no hydrogen 3.083 N/A ILE 225.A N LEU 214.A O no hydrogen 2.967 N/A GLU 226.A N LEU 214.A O no hydrogen 3.441 N/A THR 227.A N ASN 264.A O no hydrogen 2.777 N/A LEU 228.A N ASN 212.A O no hydrogen 2.951 N/A TRP 229.A N SER 262.A O no hydrogen 3.138 N/A ASN 230.A N LYS 210.A O no hydrogen 3.048 N/A ASN 230.A ND2 SER 173.A OG no hydrogen 2.536 N/A LEU 231.A N VAL 260.A O no hydrogen 2.996 N/A GLU 235.A N GLU 235.A OE1 no hydrogen 2.798 N/A LEU 237.A N ASP 233.A O no hydrogen 3.025 N/A HIS 238.A N HIS 234.A O no hydrogen 3.049 N/A MET 239.A N GLU 235.A O no hydrogen 2.830 N/A TYR 240.A N LEU 236.A O no hydrogen 2.902 N/A TYR 240.A OH LEU 125.A O no hydrogen 2.446 N/A LYS 246.A N ASN 243.A O no hydrogen 3.285 N/A LEU 247.A N VAL 244.A O no hydrogen 2.880 N/A ASP 251.A N LYS 254.A O no hydrogen 3.276 N/A CYS 259.A N THR 168.A O no hydrogen 2.532 N/A VAL 260.A N GLY 232.A O no hydrogen 2.782 N/A LEU 261.A N TRP 166.A O no hydrogen 3.009 N/A SER 262.A N TRP 229.A O no hydrogen 2.758 N/A VAL 263.A N LEU 164.A O no hydrogen 2.909 N/A ASN 264.A N THR 227.A O no hydrogen 2.976 N/A GLY 265.A N ALA 162.A O no hydrogen 3.032 N/A ASP 266.A N ILE 225.A O no hydrogen 2.615 N/A LEU 267.A N THR 160.A O no hydrogen 2.927 N/A ARG 269.A NH1 LEU 224.A O no hydrogen 3.125 N/A ARG 269.A NH2 LEU 27.A O no hydrogen 2.552 N/A GLY 270.A N ASP 266.A O no hydrogen 2.915 N/A MET 271.A N LEU 267.A O no hydrogen 2.624 N/A LEU 272.A N ASP 268.A O no hydrogen 3.383 N/A ALA 273.A N ARG 269.A O no hydrogen 2.911 N/A TYR 274.A N GLY 270.A O no hydrogen 3.159 N/A TYR 274.A N MET 271.A O no hydrogen 2.717 N/A TYR 274.A OH TRP 188.A O no hydrogen 2.292 N/A LEU 275.A N MET 271.A O no hydrogen 3.105 N/A TYR 276.A N LEU 272.A O no hydrogen 2.802 N/A TYR 276.A OH GLU 2.A OE2 no hydrogen 3.113 N/A ASP 277.A N ALA 273.A O no hydrogen 2.974 N/A SER 278.A OG TYR 274.A O no hydrogen 3.246 N/A SER 278.A OG LEU 275.A O no hydrogen 3.187 N/A PHE 279.A N TYR 276.A O no hydrogen 3.045 N/A ARG 281.A NH1 ASP 345.A OD2 no hydrogen 2.945 N/A ARG 281.A NH2 ASP 345.A OD1 no hydrogen 3.467 N/A LEU 284.A N ASP 345.A O no hydrogen 2.721 N/A LYS 285.A N SER 278.A O no hydrogen 3.117 N/A LEU 286.A N SER 348.A OG no hydrogen 3.293 N/A CYS 289.A N HIS 287.A ND1 no hydrogen 2.710 N/A LEU 290.A N HIS 287.A O no hydrogen 3.014 N/A LYS 294.A N SER 324.A OG no hydrogen 3.155 N/A LYS 294.A NZ PRO 288.A O no hydrogen 2.606 N/A LYS 294.A NZ ALA 291.A O no hydrogen 2.638 N/A VAL 295.A N SER 324.A O no hydrogen 3.324 N/A ALA 296.A N PHE 351.A O no hydrogen 3.263 N/A ASP 298.A N VAL 353.A O no hydrogen 3.351 N/A GLY 300.A N VAL 355.A O no hydrogen 2.821 N/A THR 304.A OG1 PRO 303.A O no hydrogen 2.466 N/A ARG 308.A N THR 304.A O no hydrogen 2.796 N/A CYS 311.A SG LEU 307.A O no hydrogen 3.476 N/A LEU 314.A N VAL 310.A O no hydrogen 2.705 N/A LEU 314.A N CYS 311.A O no hydrogen 3.126 N/A PHE 315.A N CYS 311.A O no hydrogen 2.591 N/A ASN 316.A N GLN 312.A O no hydrogen 3.196 N/A GLU 317.A N GLY 313.A O no hydrogen 3.091 N/A LEU 318.A N LEU 314.A O no hydrogen 2.503 N/A LEU 319.A N PHE 315.A O no hydrogen 3.140 N/A GLU 320.A N ASN 316.A O no hydrogen 2.686 N/A ASN 321.A N LEU 318.A O no hydrogen 3.233 N/A ASN 321.A ND2 GLU 317.A O no hydrogen 3.230 N/A GLY 322.A N LEU 319.A O no hydrogen 3.139 N/A ILE 323.A N LEU 318.A O no hydrogen 3.041 N/A SER 324.A OG PRO 292.A O no hydrogen 3.133 N/A TRP 326.A N VAL 295.A O no hydrogen 2.998 N/A GLY 328.A N LEU 297.A O no hydrogen 3.313 N/A GLU 331.A N GLY 328.A O no hydrogen 3.243 N/A SER 335.A OG GLN 334.A O no hydrogen 2.610 N/A SER 336.A OG GLU 338.A OE1 no hydrogen 2.776 N/A GLU 338.A N SER 336.A OG no hydrogen 3.359 N/A GLU 338.A N GLU 338.A OE1 no hydrogen 2.661 N/A GLN 339.A NE2 SER 335.A O no hydrogen 3.338 N/A SER 342.A N GLU 338.A O no hydrogen 3.018 N/A LYS 343.A NZ GLN 339.A O no hydrogen 2.802 N/A TYR 344.A OH ASP 298.A OD2 no hydrogen 3.109 N/A ASP 345.A N TYR 341.A O no hydrogen 3.099 N/A GLU 346.A N SER 342.A O no hydrogen 3.251 N/A GLU 346.A N LYS 343.A O no hydrogen 2.665 N/A MET 347.A N LYS 343.A O no hydrogen 3.051 N/A SER 348.A N ASP 345.A O no hydrogen 3.164 N/A SER 348.A OG LEU 284.A O no hydrogen 2.909 N/A SER 348.A OG SER 348.A O no hydrogen 2.581 N/A ILE 349.A N TYR 344.A O no hydrogen 2.948 N/A THR 352.A N ARG 368.A O no hydrogen 3.245 N/A VAL 355.A N ASP 298.A O no hydrogen 3.150 N/A THR 356.A N THR 359.A OG1 no hydrogen 2.895 N/A THR 356.A OG1 THR 359.A OG1 no hydrogen 3.404 N/A GLU 357.A N ARG 301.A O no hydrogen 2.976 N/A THR 358.A OG1 THR 358.A O no hydrogen 2.536 N/A THR 359.A N THR 356.A O no hydrogen 3.102 N/A THR 359.A OG1 THR 356.A O no hydrogen 2.890 N/A THR 359.A OG1 THR 356.A OG1 no hydrogen 3.404 N/A THR 359.A OG1 LEU 364.A O no hydrogen 3.083 N/A LEU 360.A N GLU 357.A O no hydrogen 2.745 N/A GLU 361.A N GLU 357.A O no hydrogen 3.240 N/A ASN 362.A ND2 THR 358.A O no hydrogen 2.849 N/A ILE 365.A N MET 378.A O no hydrogen 2.528 N/A ARG 368.A NH2 ASP 345.A OD2 no hydrogen 3.264 N/A SER 369.A N MET 374.A O no hydrogen 3.305 N/A SER 369.A OG THR 372.A OG1 no hydrogen 3.227 N/A ARG 370.A NH1 LEU 286.A O no hydrogen 3.162 N/A ARG 370.A NH2 LEU 286.A O no hydrogen 2.719 N/A ASP 371.A N SER 369.A OG no hydrogen 3.326 N/A THR 373.A OG1 THR 373.A O no hydrogen 2.388 N/A MET 378.A N ILE 365.A O no hydrogen 2.649 N/A SER 381.A OG ILE 380.A O no hydrogen 2.447 N/A LYS 382.A N HIS 379.A O no hydrogen 2.897 N/A LYS 384.A NZ ASP 385.A OD2 no hydrogen 3.435 N/A LEU 387.A N LEU 383.A O no hydrogen 2.971 N/A ILE 388.A N LYS 384.A O no hydrogen 2.943 N/A LYS 389.A N PHE 386.A O no hydrogen 3.025 N/A TYR 390.A N PHE 386.A O no hydrogen 2.857 N/A ILE 391.A N LEU 387.A O no hydrogen 2.850 N/A SER 392.A N ILE 388.A O no hydrogen 3.203 N/A SER 393.A N LYS 389.A O no hydrogen 2.442 N/A ALA 394.A N TYR 390.A O no hydrogen 2.879 N/A LYS 395.A N ILE 391.A O no hydrogen 3.224 N/A ASN 396.A N SER 392.A O no hydrogen 3.349 N/A VAL 397.A N SER 393.A O no hydrogen 3.283 N/A