Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2he8_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 4.A N ILE 12.A O no hydrogen 2.974 N/A LEU 6.A N ASN 10.A O no hydrogen 2.741 N/A ASN 7.A ND2 PRO 182.A O no hydrogen 3.003 N/A ASN 7.A ND2 ASP 206.A O no hydrogen 2.945 N/A GLY 9.A N LEU 6.A O no hydrogen 3.018 N/A ASN 10.A N ASP 8.A OD1 no hydrogen 3.018 N/A ASN 10.A ND2 ASP 8.A OD1 no hydrogen 3.381 N/A ASN 10.A ND2 ASP 8.A OD2 no hydrogen 3.214 N/A ILE 12.A N VAL 4.A O no hydrogen 3.078 N/A VAL 14.A N HIS 2.A O no hydrogen 2.841 N/A GLY 16.A N VAL 260.A O no hydrogen 2.693 N/A PHE 17.A N HIS 44.A O no hydrogen 2.792 N/A GLY 18.A N ASN 262.A O no hydrogen 2.907 N/A THR 19.A N ASP 46.A O no hydrogen 2.824 N/A THR 19.A OG1 ASP 46.A O no hydrogen 2.698 N/A CYS 25.A N PRO 22.A O no hydrogen 2.983 N/A LYS 27.A NZ TYR 51.A O no hydrogen 3.291 N/A LYS 29.A N PRO 26.A O no hydrogen 2.685 N/A LYS 29.A NZ GLU 32.A OE1 no hydrogen 2.636 N/A ALA 30.A N LYS 27.A O no hydrogen 3.002 N/A LYS 31.A N SER 28.A O no hydrogen 3.033 N/A LYS 31.A NZ GLU 59.A OE1 no hydrogen 2.509 N/A LEU 33.A N LYS 29.A O no hydrogen 3.008 N/A THR 34.A N ALA 30.A O no hydrogen 2.893 N/A THR 34.A OG1 ALA 30.A O no hydrogen 2.734 N/A LYS 35.A N LYS 31.A O no hydrogen 3.081 N/A ILE 36.A N GLU 32.A O no hydrogen 3.026 N/A ALA 37.A N LEU 33.A O no hydrogen 2.844 N/A ILE 38.A N THR 34.A O no hydrogen 2.958 N/A ASP 39.A N LYS 35.A O no hydrogen 2.988 N/A ALA 40.A N ILE 36.A O no hydrogen 2.898 N/A GLY 41.A N ILE 38.A O no hydrogen 2.976 N/A PHE 42.A N ALA 37.A O no hydrogen 2.891 N/A HIS 44.A ND1 PRO 13.A O no hydrogen 3.046 N/A PHE 45.A N PHE 76.A O no hydrogen 2.817 N/A ASP 46.A N PHE 17.A O no hydrogen 2.819 N/A SER 47.A N THR 78.A O no hydrogen 2.887 N/A SER 47.A OG THR 19.A OG1 no hydrogen 3.074 N/A SER 49.A N LYS 80.A O no hydrogen 3.229 N/A SER 49.A OG LYS 80.A O no hydrogen 3.304 N/A TYR 51.A N ALA 48.A O no hydrogen 3.258 N/A ASN 52.A N SER 49.A O no hydrogen 3.285 N/A THR 53.A OG1 THR 19.A O no hydrogen 3.390 N/A VAL 57.A N THR 53.A O no hydrogen 2.923 N/A GLY 58.A N GLU 54.A O no hydrogen 2.821 N/A GLU 59.A N ASP 55.A O no hydrogen 3.092 N/A ALA 60.A N HIS 56.A O no hydrogen 2.982 N/A ILE 61.A N VAL 57.A O no hydrogen 3.018 N/A ARG 62.A N GLY 58.A O no hydrogen 2.924 N/A ARG 62.A NE LEU 102.A O no hydrogen 2.924 N/A SER 63.A N GLU 59.A O no hydrogen 2.936 N/A LYS 64.A N ALA 60.A O no hydrogen 3.100 N/A LYS 64.A NZ ASP 39.A OD1 no hydrogen 2.783 N/A LYS 64.A NZ ASP 39.A OD2 no hydrogen 2.814 N/A ILE 65.A N ILE 61.A O no hydrogen 2.993 N/A ALA 66.A N ARG 62.A O no hydrogen 2.928 N/A ASP 67.A N SER 63.A O no hydrogen 3.182 N/A GLY 68.A N ILE 65.A O no hydrogen 3.012 N/A THR 69.A N ASP 67.A OD1 no hydrogen 2.995 N/A THR 69.A OG1 ASP 67.A OD1 no hydrogen 2.568 N/A VAL 70.A N LYS 64.A O no hydrogen 3.014 N/A ARG 71.A NE ASP 74.A OD2 no hydrogen 2.995 N/A ARG 71.A NH2 ASP 74.A OD1 no hydrogen 3.259 N/A ARG 71.A NH2 ASP 74.A OD2 no hydrogen 3.197 N/A ARG 72.A NH1 ARG 72.A O no hydrogen 2.866 N/A ARG 72.A NH1 ILE 75.A O no hydrogen 2.954 N/A ARG 72.A NH1 ASP 108.A OD1 no hydrogen 3.098 N/A ARG 72.A NH2 TYR 106.A O no hydrogen 2.916 N/A ARG 72.A NH2 ASP 108.A OD1 no hydrogen 2.966 N/A ASP 74.A N ARG 71.A O no hydrogen 2.947 N/A ILE 75.A N ARG 72.A O no hydrogen 3.068 N/A PHE 76.A N HIS 43.A O no hydrogen 2.678 N/A TYR 77.A N ASP 108.A OD1 no hydrogen 2.774 N/A TYR 77.A OH GLU 54.A OE2 no hydrogen 2.568 N/A THR 78.A N PHE 45.A O no hydrogen 2.985 N/A SER 79.A N LEU 109.A O no hydrogen 2.940 N/A SER 79.A OG GLU 54.A OE2 no hydrogen 2.729 N/A LYS 80.A NZ ASP 46.A OD1 no hydrogen 2.569 N/A LYS 80.A NZ SER 47.A O no hydrogen 2.852 N/A LYS 80.A NZ TYR 51.A OH no hydrogen 3.199 N/A VAL 81.A N LEU 111.A O no hydrogen 2.868 N/A TRP 82.A NE1 ASN 124.A O no hydrogen 2.712 N/A CYS 83.A SG MET 116.A O no hydrogen 3.137 N/A SER 85.A N TRP 82.A O no hydrogen 2.868 N/A GLU 89.A N GLU 89.A OE1 no hydrogen 2.672 N/A LEU 90.A N HIS 87.A O no hydrogen 2.821 N/A VAL 91.A N PRO 88.A O no hydrogen 3.415 N/A ARG 92.A NE GLU 96.A OE2 no hydrogen 2.913 N/A SER 94.A N LEU 90.A O no hydrogen 3.063 N/A LEU 95.A N VAL 91.A O no hydrogen 3.171 N/A GLU 96.A N ARG 92.A O no hydrogen 2.961 N/A ARG 97.A N ALA 93.A O no hydrogen 3.126 N/A SER 98.A N SER 94.A O no hydrogen 3.016 N/A SER 98.A OG GLU 54.A OE1 no hydrogen 2.629 N/A SER 98.A OG GLU 54.A OE2 no hydrogen 3.519 N/A SER 98.A OG SER 94.A O no hydrogen 3.457 N/A LEU 99.A N LEU 95.A O no hydrogen 2.972 N/A GLN 100.A N GLU 96.A O no hydrogen 2.963 N/A LYS 101.A N ARG 97.A O no hydrogen 2.930 N/A LEU 102.A N SER 98.A O no hydrogen 2.799 N/A PHE 104.A N LEU 99.A O no hydrogen 2.999 N/A VAL 107.A N LEU 155.A O no hydrogen 3.021 N/A ASP 108.A N TYR 77.A O no hydrogen 2.802 N/A LEU 109.A N TYR 77.A O no hydrogen 3.166 N/A TYR 110.A N SER 158.A O no hydrogen 2.974 N/A LEU 111.A N SER 79.A O no hydrogen 3.053 N/A ILE 112.A N GLY 160.A O no hydrogen 3.287 N/A HIS 113.A N VAL 81.A O no hydrogen 3.142 N/A LEU 118.A N CYS 83.A O no hydrogen 3.005 N/A LYS 119.A N ILE 134.A O no hydrogen 3.026 N/A ASN 124.A ND2 ASN 52.A OD1 no hydrogen 3.653 N/A ASP 128.A N LYS 132.A O no hydrogen 2.885 N/A HIS 130.A N ASP 128.A OD1 no hydrogen 2.734 N/A GLY 131.A N ASP 128.A O no hydrogen 3.090 N/A LYS 132.A N ASP 128.A OD1 no hydrogen 2.961 N/A ILE 134.A N PRO 126.A O no hydrogen 2.824 N/A ASP 136.A N ALA 117.A O no hydrogen 3.079 N/A ARG 137.A N ASP 136.A OD1 no hydrogen 2.773 N/A CYS 141.A N ASP 139.A OD1 no hydrogen 2.981 N/A CYS 141.A SG MET 171.A O no hydrogen 3.716 N/A ALA 142.A N ASP 139.A O no hydrogen 2.700 N/A THR 143.A N ASP 139.A O no hydrogen 3.007 N/A THR 143.A OG1 LEU 86.A O no hydrogen 2.721 N/A THR 143.A OG1 ASP 139.A O no hydrogen 3.513 N/A TRP 144.A N LEU 140.A O no hydrogen 2.860 N/A TRP 144.A NE1 TYR 180.A O no hydrogen 2.874 N/A GLU 145.A N CYS 141.A O no hydrogen 3.011 N/A ALA 146.A N ALA 142.A O no hydrogen 3.091 N/A MET 147.A N THR 143.A O no hydrogen 3.027 N/A GLU 148.A N TRP 144.A O no hydrogen 2.878 N/A LYS 149.A N GLU 145.A O no hydrogen 3.055 N/A LYS 149.A NZ GLU 145.A O no hydrogen 3.529 N/A CYS 150.A N ALA 146.A O no hydrogen 3.200 N/A CYS 150.A SG ALA 146.A O no hydrogen 3.284 N/A LYS 151.A N MET 147.A O no hydrogen 3.108 N/A LYS 151.A NZ ASP 8.A OD2 no hydrogen 2.917 N/A LYS 151.A NZ LYS 157.A O no hydrogen 2.790 N/A ASP 152.A N GLU 148.A O no hydrogen 2.970 N/A ALA 153.A N LYS 149.A O no hydrogen 2.839 N/A GLY 154.A N LYS 151.A O no hydrogen 3.073 N/A LEU 155.A N CYS 150.A O no hydrogen 3.046 N/A THR 156.A OG1 SER 158.A O no hydrogen 2.685 N/A LYS 157.A N VAL 107.A O no hydrogen 3.121 N/A SER 158.A N ASP 108.A O no hydrogen 2.927 N/A SER 158.A OG ASP 8.A OD1 no hydrogen 3.407 N/A SER 158.A OG ASP 8.A OD2 no hydrogen 2.662 N/A GLY 160.A N TYR 110.A O no hydrogen 3.047 N/A VAL 161.A N CYS 184.A O no hydrogen 3.030 N/A SER 162.A OG ASN 163.A OD1 no hydrogen 3.097 N/A SER 162.A OG GLN 186.A O no hydrogen 2.771 N/A ASN 163.A N GLN 186.A O no hydrogen 2.805 N/A ASN 163.A ND2 TYR 212.A OH no hydrogen 2.512 N/A PHE 164.A N ASN 185.A OD1 no hydrogen 3.345 N/A ASN 165.A N GLN 168.A OE1 no hydrogen 2.927 N/A ASN 165.A ND2 PRO 311.A O no hydrogen 3.193 N/A TYR 166.A N TYR 316.A O no hydrogen 2.833 N/A ARG 167.A NH1 ASP 314.A OD2 no hydrogen 3.252 N/A GLN 168.A N ASN 165.A OD1 no hydrogen 2.927 N/A GLN 168.A NE2 ASN 309.A O no hydrogen 3.056 N/A LEU 169.A N ASN 165.A O no hydrogen 3.081 N/A GLU 170.A N TYR 166.A O no hydrogen 2.890 N/A MET 171.A N ARG 167.A O no hydrogen 2.979 N/A ILE 172.A N GLN 168.A O no hydrogen 3.407 N/A LEU 173.A N LEU 169.A O no hydrogen 2.867 N/A ASN 174.A N GLU 170.A O no hydrogen 2.837 N/A LYS 175.A N ILE 172.A O no hydrogen 3.136 N/A LYS 175.A NZ GLU 145.A OE1 no hydrogen 2.703 N/A LYS 175.A NZ PRO 176.A O no hydrogen 3.154 N/A LEU 178.A N LYS 175.A O no hydrogen 3.093 N/A LYS 179.A N GLU 148.A OE2 no hydrogen 2.725 N/A LYS 179.A NZ ASP 152.A OD1 no hydrogen 3.315 N/A LYS 179.A NZ ASP 152.A OD2 no hydrogen 2.818 N/A TYR 180.A N GLU 148.A OE2 no hydrogen 2.788 N/A TYR 180.A OH ASP 152.A OD1 no hydrogen 2.366 N/A LYS 181.A NZ LYS 205.A O no hydrogen 2.739 N/A VAL 183.A N ILE 159.A O no hydrogen 2.889 N/A ASN 185.A N VAL 208.A O no hydrogen 3.074 N/A ASN 185.A ND2 PHE 164.A O no hydrogen 2.835 N/A GLN 186.A N VAL 161.A O no hydrogen 2.892 N/A GLN 186.A NE2 ASP 46.A OD2 no hydrogen 3.010 N/A VAL 187.A N VAL 210.A O no hydrogen 2.864 N/A CYS 189.A N TYR 212.A O no hydrogen 3.149 N/A CYS 189.A SG LEU 193.A O no hydrogen 3.655 N/A HIS 190.A N LEU 193.A O no hydrogen 3.163 N/A TYR 192.A OH GLU 231.A OE2 no hydrogen 2.502 N/A LEU 193.A N HIS 190.A O no hydrogen 2.855 N/A ASN 194.A N ASN 293.A OD1 no hydrogen 3.045 N/A MET 196.A N ASN 194.A OD1 no hydrogen 2.931 N/A LEU 199.A N GLN 195.A O no hydrogen 2.780 N/A ASP 200.A N MET 196.A O no hydrogen 2.984 N/A PHE 201.A N LYS 197.A O no hydrogen 3.052 N/A CYS 202.A N LEU 198.A O no hydrogen 2.919 N/A CYS 202.A SG LEU 198.A O no hydrogen 3.393 N/A LYS 203.A N LEU 199.A O no hydrogen 2.867 N/A SER 204.A N ASP 200.A O no hydrogen 2.991 N/A SER 204.A OG PHE 201.A O no hydrogen 2.568 N/A LYS 205.A N PHE 201.A O no hydrogen 3.092 N/A LYS 205.A N CYS 202.A O no hydrogen 2.923 N/A ASP 206.A N LYS 203.A O no hydrogen 3.185 N/A ILE 207.A N CYS 202.A O no hydrogen 2.770 N/A VAL 208.A N VAL 183.A O no hydrogen 2.998 N/A VAL 210.A N ASN 185.A O no hydrogen 3.171 N/A ALA 211.A N VAL 259.A O no hydrogen 2.768 N/A TYR 212.A N VAL 187.A O no hydrogen 3.113 N/A GLY 216.A N GLY 213.A O no hydrogen 2.970 N/A GLN 223.A N GLY 219.A O no hydrogen 2.736 N/A GLN 223.A N TRP 220.A O no hydrogen 3.156 N/A ASN 224.A N TRP 220.A O no hydrogen 2.695 N/A ASN 224.A ND2 TRP 220.A O no hydrogen 2.739 N/A SER 225.A N VAL 221.A O no hydrogen 2.843 N/A SER 225.A OG VAL 221.A O no hydrogen 3.161 N/A VAL 227.A N ASP 230.A OD1 no hydrogen 2.689 N/A LEU 228.A N TYR 298.A OH no hydrogen 3.243 N/A ASP 230.A N VAL 227.A O no hydrogen 2.594 N/A GLU 231.A N LEU 228.A O no hydrogen 2.856 N/A VAL 233.A N GLU 231.A OE1 no hydrogen 3.044 N/A GLY 235.A N GLU 231.A O no hydrogen 3.038 N/A SER 236.A N PRO 232.A O no hydrogen 2.778 N/A MET 237.A N VAL 233.A O no hydrogen 2.847 N/A ALA 238.A N LEU 234.A O no hydrogen 2.735 N/A LYS 239.A N GLY 235.A O no hydrogen 3.138 N/A LYS 240.A N SER 236.A O no hydrogen 2.845 N/A LYS 240.A NZ ASP 285.A OD1 no hydrogen 3.185 N/A LYS 240.A NZ ASP 285.A OD2 no hydrogen 3.002 N/A TYR 241.A N MET 237.A O no hydrogen 2.913 N/A TYR 241.A OH ASP 285.A OD2 no hydrogen 2.330 N/A ASN 242.A N LYS 239.A O no hydrogen 3.195 N/A ARG 243.A N ALA 238.A O no hydrogen 2.758 N/A ARG 243.A NH1 GLN 275.A OE1 no hydrogen 2.970 N/A ARG 243.A NH1 GLU 278.A OE1 no hydrogen 3.323 N/A LEU 247.A N THR 244.A OG1 no hydrogen 2.971 N/A ILE 248.A N THR 244.A O no hydrogen 3.031 N/A ALA 249.A N PRO 245.A O no hydrogen 3.134 N/A LEU 250.A N ALA 246.A O no hydrogen 2.885 N/A ARG 251.A N LEU 247.A O no hydrogen 2.924 N/A ARG 251.A NH1 VAL 276.A O no hydrogen 2.823 N/A TYR 252.A N ILE 248.A O no hydrogen 2.945 N/A TYR 252.A OH ASP 290.A OD1 no hydrogen 2.431 N/A LEU 254.A N LEU 250.A O no hydrogen 3.258 N/A GLN 255.A N ARG 251.A O no hydrogen 3.035 N/A GLN 255.A NE2 LEU 281.A O no hydrogen 3.584 N/A ARG 256.A N GLN 253.A O no hydrogen 3.041 N/A ARG 256.A NH1 ASN 194.A O no hydrogen 2.996 N/A ARG 256.A NH1 GLN 253.A OE1 no hydrogen 2.959 N/A ARG 256.A NH2 ASN 194.A O no hydrogen 2.747 N/A GLY 257.A N LEU 254.A O no hydrogen 2.996 N/A ILE 258.A N GLN 253.A O no hydrogen 3.031 N/A VAL 259.A N LEU 209.A O no hydrogen 3.103 N/A VAL 260.A N VAL 14.A O no hydrogen 2.777 N/A LEU 261.A N ALA 211.A O no hydrogen 2.973 N/A ASN 262.A N GLY 16.A O no hydrogen 2.836 N/A LYS 266.A N SER 264.A OG no hydrogen 3.168 N/A LYS 266.A NZ GLU 268.A OE1.B no hydrogen 3.556 N/A ILE 270.A N LYS 266.A O no hydrogen 3.048 N/A LYS 271.A N GLU 267.A O no hydrogen 2.941 N/A GLU 272.A N GLU 268.A O.A no hydrogen 3.028 N/A GLU 272.A N GLU 268.A O.B no hydrogen 3.056 N/A ASN 273.A ND2 ILE 270.A O no hydrogen 2.961 N/A MET 274.A N LYS 271.A O no hydrogen 3.248 N/A GLN 275.A N GLU 272.A O no hydrogen 2.842 N/A VAL 276.A N ASN 273.A O no hydrogen 2.927 N/A PHE 277.A N MET 274.A O no hydrogen 3.425 N/A GLU 278.A N GLN 275.A O no hydrogen 2.659 N/A SER 282.A N TYR 241.A OH no hydrogen 3.086 N/A SER 282.A OG ASP 285.A OD2 no hydrogen 2.776 N/A ASP 285.A N SER 282.A OG no hydrogen 3.209 N/A MET 286.A N SER 282.A O no hydrogen 2.732 N/A LYS 287.A N SER 283.A O no hydrogen 2.958 N/A VAL 288.A N GLU 284.A O no hydrogen 2.983 N/A LEU 289.A N ASP 285.A O no hydrogen 3.011 N/A ASP 290.A N MET 286.A O no hydrogen 2.984 N/A GLY 291.A N LYS 287.A O no hydrogen 3.268 N/A GLY 291.A N VAL 288.A O no hydrogen 3.009 N/A LEU 292.A N LEU 289.A O no hydrogen 3.040 N/A ARG 294.A N TYR 192.A O no hydrogen 3.028 N/A ARG 294.A NE LEU 292.A O no hydrogen 2.984 N/A MET 296.A N TYR 192.A O no hydrogen 3.088 N/A TYR 298.A N GLU 188.A OE2 no hydrogen 2.785 N/A ILE 299.A N GLU 188.A OE1 no hydrogen 2.877 N/A PHE 304.A N ALA 301.A O no hydrogen 3.075 N/A LYS 305.A N ALA 302.A O no hydrogen 2.936 N/A HIS 307.A N PHE 304.A O no hydrogen 2.558 N/A HIS 307.A NE2 ALA 117.A O no hydrogen 2.974 N/A ASN 309.A N HIS 307.A ND1 no hydrogen 2.902 N/A ASN 309.A ND2 PRO 115.A O no hydrogen 3.338 N/A TRP 310.A N HIS 307.A O no hydrogen 3.004 N/A TRP 310.A NE1 PRO 300.A O no hydrogen 3.181 N/A