Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2hl6_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 1.A N THR 228.A O no hydrogen 2.879 N/A ALA 1.A N GLN 233.A OE1 no hydrogen 3.267 N/A THR 3.A N VAL 226.A O no hydrogen 3.094 N/A GLN 4.A NE2 GLN 222.A O no hydrogen 3.086 N/A GLN 4.A NE2 ASN 223.A OD1 no hydrogen 3.390 N/A GLY 5.A N THR 224.A O no hydrogen 2.877 N/A ILE 6.A N ALA 221.A O no hydrogen 3.038 N/A LEU 10.A N SER 7.A OG no hydrogen 2.963 N/A TYR 11.A N SER 7.A O no hydrogen 2.898 N/A ASN 12.A N GLU 8.A O no hydrogen 2.828 N/A ARG 13.A N ASP 9.A O no hydrogen 3.124 N/A ARG 13.A NE TYR 156.A OH no hydrogen 2.777 N/A ARG 13.A NH1 GLU 60.A OE2 no hydrogen 2.675 N/A ARG 13.A NH2 GLU 60.A OE1 no hydrogen 2.441 N/A LEU 14.A N LEU 10.A O no hydrogen 2.949 N/A VAL 15.A N TYR 11.A O no hydrogen 2.934 N/A GLU 16.A N ASN 12.A O no hydrogen 2.925 N/A MET 17.A N ARG 13.A O no hydrogen 3.031 N/A ALA 18.A N LEU 14.A O no hydrogen 2.867 N/A THR 19.A N VAL 15.A O no hydrogen 2.881 N/A THR 19.A OG1 VAL 15.A O no hydrogen 2.753 N/A ILE 20.A N GLU 16.A O no hydrogen 3.153 N/A SER 21.A N MET 17.A O.A no hydrogen 2.971 N/A SER 21.A N MET 17.A O.B no hydrogen 2.968 N/A SER 21.A OG MET 17.A O.A no hydrogen 3.021 N/A SER 21.A OG MET 17.A O.B no hydrogen 3.022 N/A GLN 22.A N ALA 18.A O no hydrogen 2.822 N/A GLN 22.A NE2 THR 248.A O no hydrogen 2.950 N/A GLN 22.A NE2 MET 253.A O no hydrogen 2.920 N/A ALA 23.A N THR 19.A O no hydrogen 2.827 N/A ALA 24.A N ILE 20.A O no hydrogen 3.030 N/A TYR 25.A OH HIS 132.A ND1 no hydrogen 2.741 N/A ALA 26.A N ALA 23.A O no hydrogen 2.894 N/A LEU 28.A N ALA 23.A O no hydrogen 2.889 N/A CYS 29.A N ALA 26.A O no hydrogen 3.148 N/A ASN 30.A ND2 TRP 260.A O no hydrogen 3.257 N/A THR 34.A OG1 ASP 55.A OD2 no hydrogen 2.996 N/A ILE 35.A N PRO 32.A O no hydrogen 3.144 N/A ILE 36.A N ARG 54.A O no hydrogen 2.767 N/A LYS 37.A NZ ASP 27.A O no hydrogen 3.243 N/A GLY 38.A N ILE 52.A O no hydrogen 2.821 N/A LYS 40.A NZ ASN 49.A OD1 no hydrogen 2.711 N/A ILE 41.A N GLY 50.A O no hydrogen 2.772 N/A TYR 42.A N GLN 110.A OE1 no hydrogen 3.040 N/A ASN 43.A N ILE 48.A O no hydrogen 3.164 N/A THR 46.A N ASN 43.A OD1 no hydrogen 3.101 N/A THR 46.A OG1 ASN 43.A OD1 no hydrogen 3.245 N/A THR 46.A OG1 SER 106.A OG no hydrogen 2.738 N/A ILE 48.A N THR 46.A OG1 no hydrogen 3.421 N/A ASN 49.A ND2 ASP 47.A O no hydrogen 2.900 N/A ASN 49.A ND2 ASP 47.A OD1 no hydrogen 3.007 N/A GLY 50.A N ILE 41.A O no hydrogen 2.922 N/A TRP 51.A N VAL 64.A O no hydrogen 2.970 N/A ILE 52.A N GLU 39.A O no hydrogen 3.193 N/A LEU 53.A N ILE 62.A O no hydrogen 2.713 N/A ARG 54.A N ILE 36.A O no hydrogen 2.987 N/A ARG 54.A NE ASP 56.A OD1 no hydrogen 2.788 N/A ARG 54.A NH1 GLN 118.A OE1 no hydrogen 2.991 N/A ARG 54.A NH2 ASP 56.A OD2 no hydrogen 3.089 N/A ASP 55.A N GLU 60.A O no hydrogen 2.895 N/A THR 57.A N ASP 55.A OD1 no hydrogen 2.886 N/A SER 58.A N ASP 55.A OD1 no hydrogen 3.057 N/A SER 58.A OG GLU 60.A OE2 no hydrogen 2.650 N/A GLU 60.A N ASP 55.A O no hydrogen 3.131 N/A ILE 61.A N ALA 126.A O no hydrogen 2.866 N/A ILE 62.A N LEU 53.A O no hydrogen 2.871 N/A THR 63.A N THR 128.A O no hydrogen 2.861 N/A VAL 64.A N TRP 51.A O no hydrogen 3.007 N/A PHE 65.A N THR 130.A O no hydrogen 3.111 N/A ARG 66.A N ASN 49.A O no hydrogen 2.857 N/A ARG 66.A NE GLY 67.A O no hydrogen 3.028 N/A ARG 66.A NH2 ASP 47.A OD2 no hydrogen 2.950 N/A ARG 66.A NH2 ASN 73.A OD1 no hydrogen 2.744 N/A THR 68.A OG1 ASP 77.A OD2 no hydrogen 2.453 N/A GLY 69.A N ASN 73.A OD1 no hydrogen 3.175 N/A SER 70.A OG ASP 47.A OD2 no hydrogen 2.656 N/A ASN 73.A N SER 70.A OG no hydrogen 3.046 N/A ASN 73.A ND2 THR 46.A O no hydrogen 2.980 N/A ASN 73.A ND2 ASP 47.A O no hydrogen 2.894 N/A LEU 74.A N SER 70.A O no hydrogen 2.984 N/A GLN 75.A N ASP 71.A O no hydrogen 2.981 N/A LEU 76.A N THR 72.A O no hydrogen 3.434 N/A ASP 77.A N ASN 73.A O no hydrogen 2.925 N/A THR 78.A N LEU 74.A O no hydrogen 3.100 N/A THR 78.A OG1 LEU 74.A O no hydrogen 2.961 N/A ASN 79.A N LEU 76.A O no hydrogen 3.187 N/A THR 81.A N ASN 79.A OD1 no hydrogen 3.073 N/A THR 81.A OG1 ASN 79.A OD1 no hydrogen 3.275 N/A THR 83.A N VAL 96.A O no hydrogen 2.960 N/A PHE 85.A N CYS 94.A O no hydrogen 3.068 N/A LEU 88.A N PHE 85.A O no hydrogen 3.078 N/A CYS 91.A N LEU 88.A O no hydrogen 2.969 N/A CYS 94.A N CYS 91.A O no hydrogen 3.286 N/A CYS 94.A SG ASN 92.A O no hydrogen 3.876 N/A GLU 95.A N ASN 165.A OD1 no hydrogen 2.967 N/A VAL 96.A N THR 83.A O no hydrogen 2.801 N/A HIS 97.A N SER 163.A O no hydrogen 2.861 N/A HIS 97.A NE2 LEU 76.A O no hydrogen 3.206 N/A GLY 99.A N ASN 79.A O no hydrogen 3.260 N/A TYR 100.A OH ASP 77.A OD1 no hydrogen 2.463 N/A TYR 101.A N HIS 97.A O no hydrogen 2.910 N/A ILE 102.A N GLY 98.A O no hydrogen 3.187 N/A GLY 103.A N GLY 99.A O no hydrogen 3.069 N/A TRP 104.A N TYR 100.A O no hydrogen 2.833 N/A TRP 104.A NE1 THR 87.A OG1 no hydrogen 3.052 N/A ILE 105.A N TYR 101.A O no hydrogen 2.842 N/A SER 106.A N ILE 102.A O no hydrogen 3.320 N/A SER 106.A N GLY 103.A O no hydrogen 3.169 N/A SER 106.A OG THR 46.A OG1 no hydrogen 2.738 N/A SER 106.A OG GLY 103.A O no hydrogen 2.728 N/A VAL 107.A N TRP 104.A O no hydrogen 3.097 N/A GLN 108.A NE2 GLU 112.A OE1 no hydrogen 2.960 N/A GLN 110.A NE2 GLU 39.A OE2 no hydrogen 2.891 N/A GLN 110.A NE2 LYS 40.A O no hydrogen 2.889 N/A VAL 111.A N VAL 107.A O no hydrogen 2.913 N/A GLU 112.A N GLN 108.A O no hydrogen 2.857 N/A SER 113.A N ASP 109.A O no hydrogen 3.024 N/A LEU 114.A N GLN 110.A O no hydrogen 3.008 N/A VAL 115.A N VAL 111.A O no hydrogen 2.981 N/A LYS 116.A N GLU 112.A O no hydrogen 2.925 N/A GLN 117.A N SER 113.A O no hydrogen 3.095 N/A GLN 118.A N LEU 114.A O no hydrogen 3.014 N/A ALA 119.A N VAL 115.A O no hydrogen 2.784 N/A SER 120.A N LYS 116.A O no hydrogen 3.039 N/A SER 120.A OG LYS 116.A O no hydrogen 3.513 N/A SER 120.A OG GLN 117.A O no hydrogen 2.688 N/A GLN 121.A N GLN 117.A O no hydrogen 3.266 N/A GLN 121.A NE2 GLN 117.A O no hydrogen 3.514 N/A TYR 122.A N GLN 118.A O no hydrogen 2.883 N/A TYR 125.A N TYR 122.A O no hydrogen 3.162 N/A TYR 125.A OH ASP 56.A OD1 no hydrogen 2.555 N/A ALA 126.A N LYS 59.A O no hydrogen 3.021 N/A LEU 127.A N ASN 152.A O no hydrogen 3.002 N/A THR 128.A N ILE 61.A O no hydrogen 2.872 N/A THR 128.A OG1 GLU 60.A OE1 no hydrogen 2.961 N/A VAL 129.A N ARG 154.A O no hydrogen 2.913 N/A THR 130.A N THR 63.A O no hydrogen 2.893 N/A THR 130.A OG1 SER 21.A OG no hydrogen 3.100 N/A THR 130.A OG1 TYR 156.A O no hydrogen 2.705 N/A HIS 132.A ND1 TYR 25.A OH no hydrogen 2.741 N/A HIS 132.A NE2 HIS 247.A O no hydrogen 2.752 N/A SER 133.A N PHE 158.A O no hydrogen 2.956 N/A SER 133.A OG HIS 247.A NE2 no hydrogen 2.696 N/A GLY 135.A N HIS 132.A O no hydrogen 2.802 N/A ALA 136.A N SER 133.A O no hydrogen 2.855 N/A SER 137.A N SER 133.A O no hydrogen 3.257 N/A SER 137.A OG SER 163.A OG no hydrogen 2.753 N/A MET 138.A N LEU 134.A O no hydrogen 2.975 N/A ALA 139.A N GLY 135.A O no hydrogen 2.855 N/A ALA 140.A N ALA 136.A O no hydrogen 2.937 N/A LEU 141.A N SER 137.A O no hydrogen 2.996 N/A THR 142.A N MET 138.A O no hydrogen 2.993 N/A THR 142.A OG1 MET 138.A O no hydrogen 2.885 N/A ALA 143.A N ALA 139.A O no hydrogen 2.808 N/A ALA 144.A N ALA 140.A O no hydrogen 2.931 N/A GLN 145.A N LEU 141.A O no hydrogen 3.087 N/A LEU 146.A N THR 142.A O no hydrogen 2.859 N/A SER 147.A N ALA 143.A O no hydrogen 2.916 N/A SER 147.A OG ALA 143.A O no hydrogen 3.542 N/A SER 147.A OG ALA 144.A O no hydrogen 2.692 N/A ALA 148.A N GLN 145.A O no hydrogen 3.227 N/A THR 149.A N LEU 146.A O no hydrogen 2.982 N/A TYR 150.A N LEU 146.A O no hydrogen 2.963 N/A ARG 154.A N LEU 127.A O no hydrogen 2.860 N/A LEU 155.A N GLN 185.A O no hydrogen 2.813 N/A TYR 156.A N VAL 129.A O no hydrogen 3.010 N/A THR 157.A N PHE 187.A O no hydrogen 2.990 N/A THR 157.A OG1 GLU 160.A OE1 no hydrogen 2.718 N/A PHE 158.A N GLY 131.A O no hydrogen 3.092 N/A GLY 159.A N VAL 189.A O no hydrogen 3.095 N/A ARG 162.A N LEU 199.A O no hydrogen 2.860 N/A ARG 162.A NH1 PRO 200.A O no hydrogen 2.952 N/A SER 163.A OG SER 137.A OG no hydrogen 2.753 N/A SER 163.A OG GLU 160.A OE2 no hydrogen 2.654 N/A SER 163.A OG PRO 161.A O no hydrogen 3.523 N/A ASN 165.A N GLU 95.A O no hydrogen 2.903 N/A ASN 165.A ND2 ASP 93.A O no hydrogen 3.027 N/A GLN 166.A NE2 GLN 166.A O no hydrogen 3.118 N/A GLN 166.A NE2 SER 170.A OG no hydrogen 3.015 N/A PHE 168.A N ASN 165.A OD1 no hydrogen 2.970 N/A ALA 169.A N ASN 165.A O no hydrogen 2.972 N/A SER 170.A N GLN 166.A O no hydrogen 2.828 N/A SER 170.A OG GLN 166.A O no hydrogen 3.170 N/A TYR 171.A N ALA 167.A O no hydrogen 3.007 N/A MET 172.A N PHE 168.A O no hydrogen 2.992 N/A ASN 173.A N ALA 169.A O no hydrogen 2.855 N/A ASP 174.A N SER 170.A O no hydrogen 3.020 N/A ALA 175.A N TYR 171.A O no hydrogen 2.914 N/A PHE 176.A N MET 172.A O.A no hydrogen 2.903 N/A PHE 176.A N MET 172.A O.B no hydrogen 2.863 N/A GLN 177.A N ASP 174.A O no hydrogen 3.370 N/A VAL 178.A N ASN 173.A O no hydrogen 2.979 N/A GLU 182.A N SER 180.A OG no hydrogen 2.963 N/A THR 183.A N SER 180.A O no hydrogen 3.042 N/A THR 183.A OG1 GLN 177.A O no hydrogen 2.803 N/A THR 183.A OG1 SER 180.A O no hydrogen 3.140 N/A THR 184.A OG1 TYR 186.A O no hydrogen 2.874 N/A GLN 185.A N PHE 176.A O no hydrogen 2.805 N/A GLN 185.A NE2 THR 183.A O no hydrogen 3.544 N/A GLN 185.A NE2 THR 184.A O no hydrogen 2.763 N/A TYR 186.A N THR 184.A OG1 no hydrogen 3.035 N/A TYR 186.A OH GLU 160.A OE1 no hydrogen 2.622 N/A TYR 186.A OH GLU 160.A OE2 no hydrogen 3.124 N/A PHE 187.A N LEU 155.A O no hydrogen 2.857 N/A ARG 188.A N VAL 211.A O no hydrogen 2.857 N/A ARG 188.A NE GLY 209.A O no hydrogen 2.985 N/A ARG 188.A NH1 GLU 236.A OE2 no hydrogen 2.883 N/A ARG 188.A NH2 GLU 212.A OE1 no hydrogen 3.418 N/A ARG 188.A NH2 GLU 236.A OE2 no hydrogen 3.477 N/A VAL 189.A N THR 157.A O no hydrogen 2.807 N/A THR 190.A N TYR 213.A O no hydrogen 2.896 N/A THR 190.A OG1 GLU 212.A OE2 no hydrogen 2.692 N/A HIS 191.A ND1 ALA 246.A O no hydrogen 2.769 N/A HIS 191.A NE2 ASP 217.A OD1 no hydrogen 2.817 N/A SER 192.A N SER 215.A O no hydrogen 2.797 N/A ASP 194.A N HIS 191.A O no hydrogen 2.875 N/A ILE 196.A N ASP 194.A OD1 no hydrogen 2.906 N/A ASN 198.A N GLY 195.A O no hydrogen 3.108 N/A ASN 198.A ND2 GLY 195.A O no hydrogen 3.539 N/A ASN 198.A ND2 GLY 240.A O no hydrogen 3.261 N/A LEU 199.A N ILE 196.A O no hydrogen 2.916 N/A GLU 203.A N GLU 203.A OE1 no hydrogen 2.818 N/A GLN 204.A N PRO 201.A O no hydrogen 3.051 N/A GLY 205.A N ALA 202.A O no hydrogen 2.867 N/A TYR 206.A OH TYR 80.A O no hydrogen 2.628 N/A ALA 207.A N GLY 164.A O no hydrogen 2.873 N/A HIS 208.A NE2 PRO 197.A O no hydrogen 2.662 N/A GLY 210.A N ASN 173.A OD1 no hydrogen 2.833 N/A VAL 211.A N TYR 186.A O no hydrogen 3.394 N/A GLU 212.A N CYS 227.A O no hydrogen 3.098 N/A TYR 213.A N ARG 188.A O no hydrogen 2.973 N/A TRP 214.A N PHE 225.A O no hydrogen 2.819 N/A TRP 214.A NE1 SER 192.A O.A no hydrogen 2.920 N/A TRP 214.A NE1 SER 192.A O.B no hydrogen 2.914 N/A SER 215.A N THR 190.A O no hydrogen 2.856 N/A VAL 216.A N ASN 223.A O no hydrogen 2.974 N/A ASN 223.A N SER 220.A O no hydrogen 3.247 N/A ASN 223.A N SER 220.A OG no hydrogen 3.095 N/A ASN 223.A ND2 PRO 218.A O no hydrogen 2.886 N/A THR 224.A N ALA 221.A O no hydrogen 3.314 N/A THR 224.A OG1 SER 220.A O no hydrogen 2.733 N/A PHE 225.A N TRP 214.A O no hydrogen 2.858 N/A VAL 226.A N THR 3.A O no hydrogen 2.848 N/A CYS 227.A N GLU 212.A O no hydrogen 2.819 N/A THR 228.A N ALA 1.A O no hydrogen 2.865 N/A THR 228.A OG1 ALA 1.A O no hydrogen 3.391 N/A GLN 233.A NE2 ALA 1.A O no hydrogen 3.410 N/A GLN 233.A NE2 THR 228.A O no hydrogen 2.874 N/A CYS 235.A N GLU 212.A OE2 no hydrogen 3.042 N/A CYS 235.A SG SER 192.A O.A no hydrogen 3.722 N/A CYS 235.A SG SER 192.A O.B no hydrogen 3.724 N/A CYS 235.A SG ASP 194.A O no hydrogen 3.234 N/A ALA 237.A N CYS 234.A O no hydrogen 3.010 N/A GLN 238.A N CYS 235.A O no hydrogen 2.969 N/A GLN 238.A NE2 CYS 234.A O no hydrogen 3.017 N/A ASN 244.A ND2 ASN 193.A O no hydrogen 2.810 N/A HIS 247.A N ASN 244.A O no hydrogen 2.959 N/A HIS 247.A N ASN 244.A OD1 no hydrogen 3.217 N/A HIS 247.A ND1 ASP 194.A OD2 no hydrogen 2.875 N/A HIS 247.A NE2 SER 133.A OG no hydrogen 2.696 N/A THR 248.A N ASN 244.A O no hydrogen 3.393 N/A THR 248.A N ASP 245.A O no hydrogen 3.239 N/A THR 248.A OG1 ASP 245.A O no hydrogen 3.086 N/A THR 248.A OG1 THR 249.A OG1 no hydrogen 3.356 N/A THR 249.A OG1 THR 248.A OG1 no hydrogen 3.356 N/A THR 249.A OG1 THR 254.A OG1 no hydrogen 2.771 N/A TYR 250.A N MET 253.A O no hydrogen 3.049 N/A TYR 250.A OH ASP 194.A OD2 no hydrogen 2.634 N/A MET 253.A N TYR 250.A O no hydrogen 2.922 N/A THR 254.A OG1 THR 249.A OG1 no hydrogen 2.771 N/A SER 255.A N THR 248.A O no hydrogen 3.049 N/A SER 255.A OG GLN 22.A OE1 no hydrogen 2.786 N/A SER 255.A OG THR 248.A O no hydrogen 3.471 N/A GLY 256.A N GLN 22.A O no hydrogen 3.028 N/A ALA 257.A N THR 254.A O no hydrogen 2.981 N/A CYS 258.A SG GLY 256.A O no hydrogen 3.636 N/A TRP 260.A NE1 CYS 29.A O no hydrogen 3.202 N/A