Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2hlo_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 3.A OG SER 3.A O no hydrogen 2.534 N/A ASN 8.A N ILE 5.A O no hydrogen 2.551 N/A ASN 8.A ND2 ASN 8.A O no hydrogen 2.578 N/A LEU 9.A N ILE 5.A O no hydrogen 3.326 N/A ARG 10.A N ASN 8.A O no hydrogen 2.510 N/A ARG 13.A N ARG 10.A O no hydrogen 2.964 N/A SER 14.A OG VAL 11.A O no hydrogen 3.087 N/A ILE 15.A N VAL 11.A O no hydrogen 3.300 N/A LEU 16.A N LEU 12.A O no hydrogen 3.368 N/A GLU 17.A N ARG 13.A O no hydrogen 2.925 N/A ASN 18.A N SER 14.A O no hydrogen 2.846 N/A LEU 19.A N ILE 15.A O no hydrogen 2.943 N/A ARG 20.A N LEU 16.A O no hydrogen 2.891 N/A SER 21.A N GLU 17.A O no hydrogen 3.002 N/A SER 21.A N ASN 18.A O no hydrogen 2.768 N/A LYS 22.A N ASN 18.A O no hydrogen 2.773 N/A ILE 23.A N LEU 19.A O no hydrogen 2.986 N/A GLN 24.A N ARG 20.A O no hydrogen 3.440 N/A LYS 25.A N SER 21.A O no hydrogen 3.279 N/A LEU 26.A N LYS 22.A O no hydrogen 3.069 N/A GLU 27.A N ILE 23.A O no hydrogen 3.052 N/A SER 28.A N GLN 24.A O no hydrogen 3.188 N/A SER 28.A OG GLN 24.A O no hydrogen 3.128 N/A ASP 29.A N LYS 25.A O no hydrogen 3.101 N/A VAL 30.A N LEU 26.A O no hydrogen 3.069 N/A SER 31.A N GLU 27.A O no hydrogen 2.917 N/A ALA 32.A N SER 28.A O no hydrogen 2.927 N/A GLN 33.A N ASP 29.A O no hydrogen 2.907 N/A MET 34.A N VAL 30.A O no hydrogen 3.009 N/A GLU 35.A N SER 31.A O no hydrogen 3.220 N/A TYR 36.A N ALA 32.A O no hydrogen 3.069 N/A CYS 37.A N GLN 33.A O no hydrogen 3.167 N/A CYS 37.A N MET 34.A O no hydrogen 3.277 N/A CYS 37.A SG GLN 33.A O no hydrogen 3.273 N/A CYS 37.A SG GLN 33.A OE1 no hydrogen 3.398 N/A ARG 38.A N GLU 35.A O no hydrogen 2.906 N/A ARG 38.A NE GLU 35.A OE1 no hydrogen 2.762 N/A SER 44.A N ASN 123.A OD1 no hydrogen 3.034 N/A CYS 45.A SG ALA 121.A O no hydrogen 3.769 N/A ASN 46.A ND2 ASN 128.A O no hydrogen 2.384 N/A SER 51.A OG LEU 70.A O no hydrogen 2.559 N/A LYS 53.A N GLU 57.A OE1 no hydrogen 3.373 N/A CYS 55.A SG TRP 93.A O no hydrogen 3.620 N/A CYS 55.A SG THR 94.A OG1 no hydrogen 3.054 N/A GLU 56.A N GLU 54.A OE2 no hydrogen 3.312 N/A GLU 57.A N GLU 54.A OE1 no hydrogen 2.604 N/A ILE 58.A N GLU 54.A O no hydrogen 3.160 N/A ILE 59.A N CYS 55.A O no hydrogen 3.012 N/A ARG 60.A N GLU 56.A O no hydrogen 3.245 N/A LYS 61.A N ILE 58.A O no hydrogen 3.065 N/A LYS 61.A NZ SER 51.A O no hydrogen 2.774 N/A LYS 61.A NZ GLU 57.A OE2 no hydrogen 3.418 N/A GLY 63.A N ILE 58.A O no hydrogen 3.098 N/A THR 65.A OG1 GLU 67.A OE2 no hydrogen 2.687 N/A SER 66.A OG ASN 87.A OD1 no hydrogen 2.629 N/A MET 68.A N CYS 130.A O no hydrogen 3.172 N/A TYR 69.A N VAL 82.A O no hydrogen 2.940 N/A TYR 69.A OH THR 65.A O no hydrogen 2.915 N/A ILE 71.A N TYR 80.A O no hydrogen 2.852 N/A GLN 72.A N GLY 52.A O no hydrogen 2.834 N/A GLN 72.A NE2 ASP 74.A O no hydrogen 3.462 N/A GLN 72.A NE2 VAL 77.A O no hydrogen 2.856 N/A SER 76.A N ASP 74.A OD2 no hydrogen 2.975 N/A SER 76.A OG ASP 74.A OD2 no hydrogen 2.418 N/A VAL 77.A N ASP 74.A O no hydrogen 3.165 N/A TYR 80.A N ILE 71.A O no hydrogen 2.988 N/A VAL 82.A N TYR 69.A O no hydrogen 2.975 N/A TYR 83.A N TYR 136.A OH no hydrogen 3.163 N/A TYR 83.A OH GLY 131.A O no hydrogen 2.879 N/A CYS 84.A N GLU 67.A O no hydrogen 3.070 N/A ASP 85.A N TRP 93.A O no hydrogen 2.832 N/A MET 86.A N SER 66.A OG no hydrogen 2.690 N/A ASN 87.A N ASP 85.A OD2 no hydrogen 2.716 N/A THR 88.A N ASP 85.A OD2 no hydrogen 3.051 N/A THR 88.A OG1 ASP 85.A OD1 no hydrogen 2.538 N/A THR 88.A OG1 ASP 85.A OD2 no hydrogen 3.448 N/A GLY 91.A N THR 88.A O no hydrogen 2.874 N/A TRP 93.A N ASP 85.A O no hydrogen 3.201 N/A TRP 93.A NE1 THR 88.A O no hydrogen 2.939 N/A THR 94.A N ILE 298.A O no hydrogen 2.876 N/A VAL 95.A N TYR 83.A O no hydrogen 2.914 N/A ILE 96.A N MET 296.A O no hydrogen 2.752 N/A GLN 97.A N MET 296.A O no hydrogen 3.243 N/A ASN 98.A N TYR 136.A O no hydrogen 3.147 N/A ASN 98.A ND2 GLY 134.A O no hydrogen 2.765 N/A ARG 99.A N MET 294.A O no hydrogen 2.716 N/A ARG 99.A NH1 PRO 256.A O no hydrogen 2.582 N/A ARG 99.A NH1 GLY 258.A O no hydrogen 3.143 N/A ARG 99.A NH2 GLY 258.A O no hydrogen 2.994 N/A GLN 100.A N GLU 135.A OE2 no hydrogen 2.826 N/A ASP 101.A N GLU 135.A OE2 no hydrogen 2.977 N/A GLY 102.A N GLU 135.A OE2 no hydrogen 2.861 N/A SER 103.A N ASP 101.A OD1 no hydrogen 2.895 N/A SER 103.A OG ASP 101.A OD1 no hydrogen 2.657 N/A VAL 104.A N GLU 135.A OE1 no hydrogen 2.956 N/A GLY 107.A N ASP 105.A OD1 no hydrogen 2.683 N/A ARG 108.A NE ASP 105.A O no hydrogen 3.003 N/A LYS 109.A NZ TYR 222.A OH no hydrogen 2.944 N/A TRP 110.A N ASP 223.A OD1 no hydrogen 2.899 N/A TRP 110.A NE1 GLU 178.A OE2 no hydrogen 2.953 N/A TYR 113.A N LYS 109.A O no hydrogen 3.427 N/A TYR 113.A OH PHE 106.A O no hydrogen 2.711 N/A LYS 114.A N TRP 110.A O no hydrogen 3.054 N/A LYS 114.A N ASP 111.A O no hydrogen 2.999 N/A LYS 114.A NZ GLU 178.A OE1 no hydrogen 2.945 N/A GLN 115.A N ASP 111.A O no hydrogen 2.949 N/A GLY 116.A N PRO 112.A O no hydrogen 2.644 N/A PHE 117.A N TRP 137.A O no hydrogen 2.935 N/A ASN 119.A N GLU 135.A O no hydrogen 2.715 N/A THR 122.A N LEU 132.A O no hydrogen 2.759 N/A ASN 123.A ND2 SER 44.A O no hydrogen 2.841 N/A GLY 126.A N ASP 125.A OD1 no hydrogen 2.585 N/A LYS 127.A N THR 124.A O no hydrogen 3.267 N/A GLY 131.A N THR 124.A OG1 no hydrogen 3.174 N/A LEU 132.A N THR 122.A O no hydrogen 3.378 N/A GLY 134.A N VAL 120.A O no hydrogen 3.153 N/A TYR 136.A N ASN 98.A O no hydrogen 3.377 N/A TYR 136.A OH VAL 95.A O no hydrogen 2.637 N/A TRP 137.A N PHE 117.A O no hydrogen 2.922 N/A LEU 138.A N ILE 96.A O no hydrogen 2.931 N/A ASN 140.A N TYR 113.A O no hydrogen 2.959 N/A ASP 141.A N LYS 114.A O no hydrogen 3.440 N/A ILE 143.A N GLY 139.A O no hydrogen 2.852 N/A SER 144.A N ASN 140.A O no hydrogen 2.905 N/A SER 144.A OG VAL 175.A O no hydrogen 2.591 N/A GLN 145.A N ASP 141.A O no hydrogen 3.069 N/A LEU 146.A N LYS 142.A O no hydrogen 3.021 N/A THR 147.A N ILE 143.A O no hydrogen 3.049 N/A THR 147.A OG1 ILE 143.A O no hydrogen 3.337 N/A THR 147.A OG1 SER 144.A O no hydrogen 2.993 N/A ARG 148.A N SER 144.A O no hydrogen 3.259 N/A ARG 148.A N GLN 145.A O no hydrogen 3.324 N/A ARG 148.A NE SER 144.A O no hydrogen 3.449 N/A MET 149.A N LEU 146.A O no hydrogen 3.486 N/A THR 152.A OG1 GLY 150.A O no hydrogen 2.884 N/A GLU 153.A N ARG 299.A O no hydrogen 2.738 N/A LEU 154.A N TYR 170.A O no hydrogen 2.842 N/A LEU 155.A N LYS 297.A O no hydrogen 2.850 N/A ILE 156.A N ALA 168.A O no hydrogen 2.896 N/A GLU 157.A N SER 295.A O no hydrogen 3.221 N/A MET 158.A N VAL 166.A O no hydrogen 3.161 N/A GLU 159.A N LYS 293.A O no hydrogen 2.771 N/A ASP 160.A N ASP 164.A O no hydrogen 3.013 N/A TRP 161.A N TYR 289.A OH no hydrogen 2.916 N/A TRP 161.A NE1 SER 290.A O no hydrogen 2.777 N/A LYS 162.A N ASP 160.A OD2 no hydrogen 2.811 N/A GLY 163.A N ASP 160.A O no hydrogen 3.454 N/A VAL 166.A N MET 158.A O no hydrogen 3.198 N/A LYS 167.A N THR 192.A OG1 no hydrogen 3.026 N/A LYS 167.A NZ GLU 89.A OE1 no hydrogen 3.271 N/A LYS 167.A NZ GLU 89.A OE2 no hydrogen 2.500 N/A ALA 168.A N ILE 156.A O no hydrogen 2.728 N/A HIS 169.A N ARG 190.A O no hydrogen 2.763 N/A TYR 170.A N LEU 154.A O no hydrogen 2.784 N/A GLY 171.A N LYS 188.A O no hydrogen 2.923 N/A GLY 172.A N ASN 187.A O no hydrogen 3.162 N/A PHE 173.A N THR 152.A O no hydrogen 2.794 N/A THR 174.A N SER 185.A O no hydrogen 2.950 N/A VAL 175.A N THR 147.A OG1 no hydrogen 3.185 N/A GLN 176.A N GLN 183.A O no hydrogen 3.150 N/A ASN 180.A N ASN 177.A O no hydrogen 3.225 N/A ASN 180.A N ASN 177.A OD1 no hydrogen 3.256 N/A ASN 180.A ND2 ASN 177.A OD1 no hydrogen 2.983 N/A LYS 181.A N GLU 178.A O no hydrogen 2.814 N/A TYR 182.A N ASN 177.A O no hydrogen 2.833 N/A TYR 182.A OH ASP 141.A OD1 no hydrogen 2.516 N/A GLN 183.A N ASN 180.A O no hydrogen 3.303 N/A ILE 184.A N MET 217.A O no hydrogen 3.032 N/A SER 185.A N THR 174.A O no hydrogen 3.085 N/A VAL 186.A N ASN 215.A OD1 no hydrogen 3.141 N/A ASN 187.A N GLY 172.A O no hydrogen 3.053 N/A LYS 188.A NZ ASN 187.A OD1 no hydrogen 2.907 N/A TYR 189.A OH ALA 193.A O no hydrogen 2.443 N/A ARG 190.A N HIS 169.A O no hydrogen 2.922 N/A THR 192.A N LYS 167.A O no hydrogen 2.919 N/A ALA 193.A N LYS 167.A O no hydrogen 3.077 N/A ALA 196.A N GLY 194.A O no hydrogen 2.692 N/A LEU 197.A N TYR 170.A OH no hydrogen 3.356 N/A ASP 199.A N ASN 195.A O no hydrogen 3.095 N/A GLY 200.A N ALA 196.A O no hydrogen 2.985 N/A ALA 201.A N THR 212.A OG1 no hydrogen 2.864 N/A SER 202.A OG ASN 283.A OD1 no hydrogen 3.377 N/A GLN 203.A N GLN 203.A OE1 no hydrogen 2.747 N/A ARG 209.A N MET 205.A O no hydrogen 3.030 N/A ARG 209.A N GLY 206.A O no hydrogen 3.200 N/A ARG 209.A NH1 ASP 199.A O no hydrogen 2.726 N/A THR 210.A N GLY 206.A O no hydrogen 3.329 N/A THR 210.A OG1 GLY 206.A O no hydrogen 3.404 N/A MET 211.A N GLU 207.A O no hydrogen 3.173 N/A THR 212.A N ARG 209.A O no hydrogen 2.865 N/A THR 212.A OG1 ARG 209.A O no hydrogen 2.796 N/A HIS 214.A N LEU 197.A O no hydrogen 2.979 N/A HIS 214.A ND1 TRP 247.A O no hydrogen 2.976 N/A ASN 215.A N LEU 197.A O no hydrogen 2.881 N/A GLY 216.A N ILE 184.A O no hydrogen 3.019 N/A MET 217.A N HIS 214.A O no hydrogen 2.920 N/A PHE 219.A N LYS 181.A O no hydrogen 3.114 N/A SER 220.A N TRP 246.A O no hydrogen 2.764 N/A THR 221.A N ARG 224.A O no hydrogen 3.063 N/A THR 221.A OG1 ASP 223.A OD1 no hydrogen 2.841 N/A ARG 224.A N THR 221.A O no hydrogen 2.749 N/A ASN 226.A N SER 220.A OG no hydrogen 2.843 N/A ASN 226.A ND2 PHE 219.A O no hydrogen 3.077 N/A ASP 227.A N ASP 225.A OD1 no hydrogen 3.186 N/A GLY 228.A N ASN 249.A O no hydrogen 2.691 N/A TRP 229.A N ASP 227.A OD1 no hydrogen 2.656 N/A LEU 230.A N GLY 228.A O no hydrogen 2.916 N/A ARG 235.A N ASP 233.A OD2 no hydrogen 2.769 N/A ARG 235.A NE PRO 234.A O no hydrogen 2.844 N/A ARG 235.A NH2 PRO 234.A O no hydrogen 2.842 N/A CYS 238.A N ASP 227.A OD2 no hydrogen 3.067 N/A CYS 238.A SG ASP 227.A OD2 no hydrogen 3.780 N/A CYS 238.A SG ASN 249.A O no hydrogen 3.605 N/A SER 239.A OG GLY 244.A O no hydrogen 3.332 N/A LYS 240.A NZ ARG 235.A O no hydrogen 3.256 N/A GLY 243.A N LYS 240.A O no hydrogen 2.871 N/A GLY 245.A N TYR 113.A OH no hydrogen 2.919 N/A TRP 246.A N SER 220.A O no hydrogen 3.161 N/A TRP 247.A NE1 TYR 182.A O no hydrogen 2.767 N/A TYR 248.A OH GLY 244.A O no hydrogen 2.648 N/A ASN 249.A N CYS 251.A O no hydrogen 2.828 N/A ASN 249.A ND2 ILE 213.A O no hydrogen 3.044 N/A ARG 250.A N MET 211.A O no hydrogen 2.958 N/A ALA 253.A N HIS 214.A NE2 no hydrogen 3.033 N/A ALA 254.A N HIS 214.A NE2 no hydrogen 3.227 N/A ASN 255.A N VAL 280.A O no hydrogen 2.755 N/A ASN 255.A ND2 TYR 248.A OH no hydrogen 3.017 N/A ASN 257.A N ASN 255.A OD1 no hydrogen 3.260 N/A ASN 257.A ND2 GLY 245.A O no hydrogen 2.759 N/A GLY 258.A N ASN 255.A O no hydrogen 3.356 N/A ARG 259.A N ASP 277.A O no hydrogen 2.652 N/A ARG 259.A NH1 ASP 242.A OD2 no hydrogen 2.643 N/A TYR 260.A OH ARG 292.A O no hydrogen 2.763 N/A TYR 261.A OH ASP 277.A OD2 no hydrogen 2.737 N/A TYR 266.A N TRP 288.A O no hydrogen 3.068 N/A THR 267.A OG1 ASP 269.A OD1 no hydrogen 2.858 N/A MET 270.A N THR 267.A O no hydrogen 3.284 N/A GLY 274.A N ALA 271.A O no hydrogen 2.978 N/A GLY 278.A N TYR 266.A OH no hydrogen 2.973 N/A VAL 279.A N SER 290.A OG no hydrogen 3.016 N/A VAL 280.A N ASN 255.A O no hydrogen 3.215 N/A TRP 281.A NE1 GLY 194.A O no hydrogen 3.079 N/A MET 282.A N ALA 253.A O no hydrogen 2.945 N/A ASN 283.A ND2 GLY 200.A O no hydrogen 3.646 N/A TRP 284.A N TRP 281.A O no hydrogen 2.961 N/A LYS 285.A N TRP 281.A O no hydrogen 3.320 N/A LYS 285.A NZ ASP 160.A OD1 no hydrogen 2.971 N/A GLY 286.A N MET 282.A O no hydrogen 2.983 N/A SER 290.A N GLY 264.A O no hydrogen 2.838 N/A SER 290.A OG ARG 259.A O no hydrogen 3.378 N/A MET 291.A N VAL 279.A O no hydrogen 2.888 N/A ARG 292.A N GLU 159.A O no hydrogen 2.788 N/A LYS 293.A N GLU 159.A O no hydrogen 3.175 N/A MET 294.A N ARG 99.A O no hydrogen 3.138 N/A SER 295.A N GLU 157.A O no hydrogen 2.944 N/A SER 295.A OG GLU 157.A O no hydrogen 3.528 N/A MET 296.A N GLN 97.A O no hydrogen 2.883 N/A LYS 297.A N LEU 155.A O no hydrogen 3.002 N/A LYS 297.A NZ ASP 85.A OD1 no hydrogen 2.706 N/A LYS 297.A NZ GLU 157.A OE1 no hydrogen 2.834 N/A ILE 298.A N THR 94.A O no hydrogen 2.918 N/A ARG 299.A N GLU 153.A O no hydrogen 3.191 N/A ARG 299.A NE GLU 153.A OE2 no hydrogen 3.151 N/A ARG 299.A NH1 GLU 89.A O no hydrogen 3.397 N/A ARG 299.A NH1 GLY 91.A O no hydrogen 3.117 N/A ARG 299.A NH2 GLU 153.A OE2 no hydrogen 2.757 N/A PHE 301.A N PRO 151.A O no hydrogen 2.892 N/A