Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2hmc_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 2.A N GLU 182.A OE2 no hydrogen 2.576 N/A GLN 3.A NE2 SER 7.A OG no hydrogen 2.952 N/A GLY 4.A N TYR 1.A O.A no hydrogen 3.265 N/A GLY 4.A N TYR 1.A O.B no hydrogen 2.755 N/A ILE 8.A N GLN 3.A OE1 no hydrogen 3.011 N/A PHE 9.A N SER 7.A OG no hydrogen 3.137 N/A SER 10.A N.A SER 7.A O no hydrogen 3.263 N/A SER 10.A N.B SER 7.A O no hydrogen 3.240 N/A SER 10.A OG.A SER 7.A O no hydrogen 2.890 N/A GLY 11.A N THR 202.A O no hydrogen 3.141 N/A ILE 13.A N ALA 204.A O no hydrogen 2.781 N/A ALA 15.A N THR 206.A O no hydrogen 2.931 N/A LEU 16.A N VAL 45.A O no hydrogen 3.144 N/A THR 17.A OG1 TYR 46.A OH no hydrogen 2.834 N/A THR 17.A OG1 GLY 50.A O no hydrogen 2.688 N/A CYS 19.A SG ARG 20.A O no hydrogen 3.684 N/A ARG 20.A N THR 24.A O no hydrogen 2.870 N/A ARG 20.A NH2 THR 24.A OG1 no hydrogen 3.358 N/A GLN 21.A NE2 GLN 21.A O no hydrogen 3.596 N/A ARG 23.A N ARG 20.A O no hydrogen 2.869 N/A ARG 23.A NH1 HIS 273.A O no hydrogen 2.904 N/A THR 24.A N ASP 22.A OD1 no hydrogen 3.117 N/A THR 24.A OG1 ASP 22.A OD1 no hydrogen 2.914 N/A THR 24.A OG1 ASP 22.A OD2 no hydrogen 3.118 N/A ASP 26.A N PRO 18.A O no hydrogen 2.708 N/A ALA 29.A N ASP 26.A OD1 no hydrogen 3.224 N/A LEU 30.A N ASP 26.A O no hydrogen 3.074 N/A VAL 31.A N PHE 27.A O no hydrogen 2.971 N/A ARG 32.A N ASP 28.A O no hydrogen 2.916 N/A ARG 32.A NH2 GLU 269.A OE2 no hydrogen 3.219 N/A LYS 33.A N ALA 29.A O no hydrogen 2.968 N/A LYS 33.A NZ GLU 36.A OE1 no hydrogen 2.682 N/A LYS 33.A NZ ASP 267.A OD2 no hydrogen 2.729 N/A GLY 34.A N LEU 30.A O no hydrogen 2.903 N/A LYS 35.A N VAL 31.A O no hydrogen 2.869 N/A GLU 36.A N ARG 32.A O no hydrogen 2.959 N/A LEU 37.A N LYS 33.A O no hydrogen 2.945 N/A ILE 38.A N GLY 34.A O no hydrogen 3.097 N/A ALA 39.A N LYS 35.A O no hydrogen 3.063 N/A ASP 40.A N GLU 36.A O no hydrogen 2.983 N/A GLY 41.A N ILE 38.A O no hydrogen 2.924 N/A SER 42.A N VAL 12.A O no hydrogen 2.852 N/A VAL 44.A N PRO 72.A O no hydrogen 2.954 N/A VAL 45.A N PRO 14.A O no hydrogen 2.801 N/A TYR 46.A N ILE 74.A O no hydrogen 3.010 N/A TYR 46.A OH THR 17.A OG1 no hydrogen 2.834 N/A CYS 47.A SG GLY 48.A O no hydrogen 3.765 N/A CYS 47.A SG GLY 50.A O no hydrogen 3.169 N/A GLY 50.A N LEU 16.A O no hydrogen 3.186 N/A ASP 51.A N SER 49.A O.A no hydrogen 3.329 N/A ASP 51.A N SER 49.A O.B no hydrogen 2.853 N/A TRP 52.A N GLY 48.A O no hydrogen 3.342 N/A LEU 54.A N ASP 51.A O no hydrogen 2.829 N/A LEU 55.A N TRP 52.A O no hydrogen 3.096 N/A THR 56.A N GLN 59.A OE1 no hydrogen 2.982 N/A GLN 59.A N THR 56.A OG1 no hydrogen 2.892 N/A ARG 60.A N THR 56.A O no hydrogen 3.154 N/A ARG 60.A NH1 GLY 78.A O no hydrogen 2.563 N/A ARG 60.A NH2 GLY 76.A O no hydrogen 2.925 N/A ARG 60.A NH2 GLY 78.A O no hydrogen 2.679 N/A GLY 62.A N GLN 59.A O no hydrogen 2.981 N/A VAL 63.A N ARG 60.A O no hydrogen 2.847 N/A ARG 65.A N GLU 61.A O no hydrogen 2.951 N/A ARG 65.A NH2 ASP 28.A OD1 no hydrogen 2.627 N/A LEU 66.A N GLY 62.A O no hydrogen 2.992 N/A VAL 67.A N VAL 63.A O no hydrogen 2.847 N/A LYS 68.A N GLU 64.A O no hydrogen 2.779 N/A LYS 68.A NZ GLU 64.A OE2 no hydrogen 2.674 N/A ALA 69.A N ARG 65.A O no hydrogen 3.059 N/A ALA 69.A N LEU 66.A O no hydrogen 3.268 N/A GLY 70.A N VAL 67.A O no hydrogen 3.101 N/A ILE 71.A N LEU 66.A O no hydrogen 3.271 N/A ILE 74.A N VAL 44.A O no hydrogen 2.797 N/A VAL 75.A N GLY 99.A O no hydrogen 2.935 N/A GLY 76.A N TYR 46.A O no hydrogen 2.965 N/A SER 84.A N ASN 81.A OD1 no hydrogen 2.871 N/A SER 84.A OG ASP 57.A OD1 no hydrogen 3.228 N/A SER 84.A OG ASP 57.A OD2 no hydrogen 2.579 N/A ALA 85.A N ASN 81.A O no hydrogen 3.058 N/A VAL 86.A N THR 82.A O no hydrogen 2.799 N/A ALA 87.A N ALA 83.A O no hydrogen 2.988 N/A HIS 88.A N SER 84.A O no hydrogen 3.149 N/A HIS 88.A NE2 ASP 57.A OD1 no hydrogen 2.914 N/A ALA 89.A N ALA 85.A O no hydrogen 3.152 N/A VAL 90.A N VAL 86.A O no hydrogen 2.842 N/A HIS 91.A N ALA 87.A O no hydrogen 3.024 N/A ALA 92.A N HIS 88.A O no hydrogen 2.924 N/A GLN 93.A N ALA 89.A O no hydrogen 3.154 N/A LYS 94.A N.A VAL 90.A O no hydrogen 2.986 N/A LYS 94.A N.B VAL 90.A O no hydrogen 3.003 N/A VAL 95.A N HIS 91.A O no hydrogen 2.953 N/A GLY 96.A N ALA 92.A O no hydrogen 3.109 N/A ALA 97.A N ALA 92.A O no hydrogen 3.001 N/A LYS 98.A N VAL 73.A O no hydrogen 2.910 N/A GLY 99.A N VAL 73.A O no hydrogen 3.142 N/A LEU 100.A N PRO 130.A O no hydrogen 2.905 N/A ILE 102.A N THR 77.A OG1 no hydrogen 3.045 N/A ARG 104.A N GLN 115.A OE1 no hydrogen 2.758 N/A ARG 104.A NE SER 107.A O no hydrogen 2.642 N/A ARG 104.A NH2 SER 107.A OG no hydrogen 2.814 N/A VAL 111.A N ARG 108.A O no hydrogen 2.963 N/A GLN 115.A N VAL 111.A O no hydrogen 2.965 N/A GLN 115.A NE2 ARG 104.A O no hydrogen 3.038 N/A GLN 115.A NE2 GLY 109.A O no hydrogen 2.868 N/A LYS 116.A N ILE 112.A O no hydrogen 2.817 N/A ALA 117.A N ALA 113.A O no hydrogen 3.301 N/A HIS 118.A N ALA 114.A O no hydrogen 2.986 N/A PHE 119.A N GLN 115.A O no hydrogen 2.834 N/A LYS 120.A N LYS 116.A O no hydrogen 2.935 N/A LYS 120.A NZ HIS 155.A NE2 no hydrogen 2.936 N/A ALA 121.A N ALA 117.A O no hydrogen 2.959 N/A ILE 122.A N HIS 118.A O no hydrogen 3.026 N/A LEU 123.A N PHE 119.A O no hydrogen 2.792 N/A SER 124.A N LYS 120.A O no hydrogen 2.930 N/A SER 124.A OG LYS 120.A O no hydrogen 2.573 N/A ALA 125.A N ILE 122.A O no hydrogen 2.990 N/A GLU 128.A N GLN 93.A OE1 no hydrogen 2.912 N/A ILE 129.A N ALA 126.A O no hydrogen 3.149 N/A ALA 131.A N ASN 157.A O no hydrogen 2.622 N/A VAL 132.A N.A LEU 100.A O no hydrogen 3.020 N/A VAL 132.A N.B LEU 100.A O no hydrogen 3.045 N/A ILE 133.A N GLY 160.A O no hydrogen 3.191 N/A TYR 134.A N VAL 101.A O no hydrogen 2.970 N/A ASN 135.A N LYS 162.A O no hydrogen 2.810 N/A ASN 135.A ND2 GLU 163.A OE1 no hydrogen 2.725 N/A TYR 138.A N.A SER 136.A OG no hydrogen 3.277 N/A TYR 138.A N.B SER 136.A OG no hydrogen 3.328 N/A TYR 138.A OH.B GLU 252.A O no hydrogen 2.990 N/A TYR 139.A N SER 136.A O no hydrogen 3.404 N/A GLY 140.A N PRO 137.A O no hydrogen 3.210 N/A THR 143.A N ASN 135.A OD1 no hydrogen 2.859 N/A ALA 145.A N TYR 171.A OH no hydrogen 2.920 N/A LEU 147.A N ASP 146.A OD1 no hydrogen 2.892 N/A PHE 148.A N ARG 144.A O no hydrogen 2.906 N/A PHE 149.A N ALA 145.A O no hydrogen 2.967 N/A ALA 150.A N ASP 146.A O no hydrogen 3.057 N/A LEU 151.A N LEU 147.A O no hydrogen 2.976 N/A ARG 152.A N PHE 148.A O no hydrogen 2.945 N/A ARG 152.A NE LEU 158.A O no hydrogen 2.856 N/A ARG 152.A NH2 LEU 158.A O no hydrogen 2.975 N/A ARG 152.A NH2 GLU 182.A OE1 no hydrogen 2.595 N/A ALA 153.A N PHE 149.A O no hydrogen 3.049 N/A GLU 154.A N LEU 151.A O no hydrogen 2.983 N/A HIS 155.A N ARG 152.A O no hydrogen 3.321 N/A ASN 157.A ND2 LEU 123.A O no hydrogen 3.301 N/A ASN 157.A ND2 ILE 129.A O no hydrogen 3.102 N/A LEU 158.A N HIS 155.A O no hydrogen 3.026 N/A VAL 159.A N ALA 131.A O no hydrogen 2.868 N/A GLY 160.A N ALA 131.A O no hydrogen 3.125 N/A PHE 161.A N THR 184.A O no hydrogen 2.999 N/A LYS 162.A N ILE 133.A O no hydrogen 2.758 N/A PHE 164.A N ASN 135.A O no hydrogen 3.016 N/A GLY 165.A N GLU 163.A OE2 no hydrogen 2.755 N/A ARG 170.A NE.A GLU 174.A OE2 no hydrogen 2.518 N/A ARG 170.A NE.B HIS 194.A NE2 no hydrogen 3.483 N/A ARG 170.A NH1.A GLU 174.A OE2 no hydrogen 2.471 N/A ARG 170.A NH2.B HIS 194.A NE2 no hydrogen 3.212 N/A TYR 171.A N ALA 168.A O no hydrogen 3.037 N/A ALA 172.A N ASP 169.A O no hydrogen 3.083 N/A GLU 174.A N ARG 170.A O.A no hydrogen 2.752 N/A GLU 174.A N ARG 170.A O.B no hydrogen 2.819 N/A ASN 175.A N TYR 171.A O no hydrogen 2.868 N/A ILE 176.A N ALA 172.A O no hydrogen 2.857 N/A THR 177.A N ALA 172.A O no hydrogen 2.981 N/A THR 177.A OG1 ALA 172.A O no hydrogen 3.459 N/A SER 178.A OG ALA 173.A O no hydrogen 2.643 N/A ASP 181.A N ARG 179.A O no hydrogen 2.747 N/A VAL 183.A N ASP 181.A OD1 no hydrogen 2.810 N/A THR 184.A N VAL 159.A O no hydrogen 2.989 N/A ASP 189.A N ASP 251.A OD2 no hydrogen 2.935 N/A THR 190.A OG1 GLU 252.A OE2 no hydrogen 2.627 N/A ALA 191.A N VAL 188.A O no hydrogen 3.349 N/A VAL 193.A N GLU 241.A OE2 no hydrogen 3.294 N/A GLY 195.A N ALA 191.A O no hydrogen 2.823 N/A PHE 196.A N VAL 192.A O no hydrogen 2.974 N/A VAL 197.A N VAL 193.A O no hydrogen 2.897 N/A ASN 198.A N HIS 194.A O no hydrogen 2.971 N/A CYS 199.A SG HIS 194.A O no hydrogen 3.576 N/A ALA 201.A N GLY 195.A O no hydrogen 2.795 N/A THR 202.A N LEU 185.A O no hydrogen 3.063 N/A ALA 204.A N GLY 11.A O no hydrogen 2.854 N/A ILE 205.A N ILE 186.A O no hydrogen 2.892 N/A THR 206.A N ILE 13.A O no hydrogen 2.799 N/A THR 206.A OG1 ASP 189.A OD1 no hydrogen 3.320 N/A GLY 207.A N ASP 189.A OD1 no hydrogen 2.762 N/A GLY 207.A N ASP 189.A OD2 no hydrogen 3.240 N/A ILE 208.A N ASP 189.A OD2 no hydrogen 2.830 N/A GLY 209.A N THR 206.A OG1 no hydrogen 2.905 N/A ASN 210.A N GLY 207.A O no hydrogen 3.037 N/A ASN 210.A ND2 ALA 15.A O no hydrogen 2.956 N/A ASN 210.A ND2 GLY 207.A O no hydrogen 2.847 N/A VAL 211.A N ILE 208.A O no hydrogen 2.822 N/A LEU 212.A N ILE 208.A O no hydrogen 2.784 N/A LYS 214.A NZ ASP 40.A O no hydrogen 3.549 N/A GLU 215.A N GLU 215.A OE1 no hydrogen 2.790 N/A VAL 216.A N LEU 212.A O no hydrogen 2.984 N/A ILE 217.A N PRO 213.A O no hydrogen 2.884 N/A HIS 218.A N LYS 214.A O no hydrogen 2.829 N/A HIS 218.A ND1 TYR 299.A OH no hydrogen 3.023 N/A LEU 219.A N GLU 215.A O no hydrogen 3.014 N/A CYS 220.A N VAL 216.A O no hydrogen 2.947 N/A CYS 220.A SG VAL 216.A O no hydrogen 3.449 N/A LYS 221.A N ILE 217.A O no hydrogen 2.867 N/A LEU 222.A N HIS 218.A O no hydrogen 2.910 N/A SER 223.A N LEU 219.A O no hydrogen 2.871 N/A SER 223.A OG LEU 219.A O no hydrogen 2.866 N/A GLN 224.A N CYS 220.A O no hydrogen 2.787 N/A ALA 225.A N LYS 221.A O no hydrogen 3.080 N/A ALA 226.A N LEU 222.A O no hydrogen 2.789 N/A ALA 227.A N SER 223.A O no hydrogen 2.817 N/A LYS 228.A N ALA 225.A O no hydrogen 2.974 N/A GLY 229.A N ALA 226.A O no hydrogen 2.986 N/A ASP 230.A N ALA 225.A O no hydrogen 3.378 N/A ALA 233.A N ASP 230.A OD1 no hydrogen 2.913 N/A ARG 234.A N.A ASP 230.A O no hydrogen 3.099 N/A ARG 234.A N.B ASP 230.A O no hydrogen 3.119 N/A ALA 235.A N ALA 231.A O no hydrogen 3.178 N/A ARG 236.A N ASP 232.A O.A no hydrogen 3.022 N/A ARG 236.A N ASP 232.A O.B no hydrogen 3.021 N/A ALA 237.A N ALA 233.A O no hydrogen 2.783 N/A LEU 238.A N ARG 234.A O.A no hydrogen 3.051 N/A LEU 238.A N ARG 234.A O.B no hydrogen 2.981 N/A GLU 239.A N ALA 235.A O no hydrogen 3.295 N/A LEU 240.A N ARG 236.A O no hydrogen 3.028 N/A GLU 241.A N ALA 237.A O no hydrogen 2.866 N/A GLN 242.A N LEU 238.A O no hydrogen 3.016 N/A ALA 243.A N GLU 239.A O no hydrogen 2.927 N/A LEU 244.A N LEU 240.A O no hydrogen 2.904 N/A ALA 245.A N GLN 242.A O no hydrogen 3.172 N/A SER 248.A N LEU 244.A O no hydrogen 2.882 N/A SER 248.A OG LEU 244.A O no hydrogen 2.572 N/A SER 249.A N ALA 245.A O no hydrogen 2.918 N/A SER 249.A N VAL 246.A O no hydrogen 3.033 N/A SER 249.A OG VAL 246.A O no hydrogen 2.575 N/A PHE 250.A N LEU 247.A O no hydrogen 3.341 N/A ASP 251.A N SER 248.A O no hydrogen 3.035 N/A GLU 252.A N SER 249.A O no hydrogen 3.053 N/A GLY 253.A N PHE 250.A O no hydrogen 3.449 N/A TYR 259.A N ASP 255.A O no hydrogen 2.841 N/A PHE 260.A N LEU 256.A O no hydrogen 2.858 N/A LYS 261.A N VAL 257.A O no hydrogen 2.958 N/A LYS 261.A NZ THR 17.A O no hydrogen 2.691 N/A LYS 261.A NZ LEU 272.A O no hydrogen 3.368 N/A TYR 262.A N LEU 258.A O no hydrogen 3.218 N/A TYR 262.A OH GLU 289.A OE2 no hydrogen 2.419 N/A LEU 264.A N TYR 262.A O no hydrogen 2.864 N/A LYS 265.A NZ VAL 211.A O no hydrogen 2.885 N/A GLY 266.A N VAL 263.A O no hydrogen 2.789 N/A LYS 268.A NZ.A VAL 263.A O no hydrogen 2.808 N/A GLU 269.A N GLU 269.A OE1 no hydrogen 2.735 N/A TYR 270.A N ASP 267.A O no hydrogen 3.300 N/A THR 271.A N LYS 268.A O.A no hydrogen 3.264 N/A THR 271.A N LYS 268.A O.B no hydrogen 3.015 N/A THR 271.A OG1 LYS 268.A O.A no hydrogen 2.763 N/A THR 271.A OG1 LYS 268.A O.B no hydrogen 2.653 N/A ASP 278.A N ASN 275.A O no hydrogen 3.138 N/A THR 281.A N GLN 284.A OE1 no hydrogen 2.881 N/A THR 281.A OG1 GLN 284.A OE1 no hydrogen 3.319 N/A GLN 284.A N THR 281.A OG1 no hydrogen 3.226 N/A GLN 284.A NE2 ASP 255.A OD2 no hydrogen 3.496 N/A ARG 285.A N.A THR 281.A O no hydrogen 2.910 N/A ARG 285.A N.B THR 281.A O no hydrogen 2.903 N/A ARG 285.A NH1.A ASP 282.A OD1 no hydrogen 2.504 N/A GLY 286.A N ASP 282.A O no hydrogen 3.025 N/A TYR 287.A N SER 283.A O no hydrogen 2.838 N/A VAL 288.A N.A GLN 284.A O no hydrogen 2.952 N/A VAL 288.A N.B GLN 284.A O no hydrogen 2.958 N/A GLU 289.A N ARG 285.A O.A no hydrogen 2.888 N/A GLU 289.A N ARG 285.A O.B no hydrogen 3.050 N/A ALA 290.A N GLY 286.A O no hydrogen 3.019 N/A GLN 291.A N TYR 287.A O no hydrogen 3.039 N/A PHE 292.A N VAL 288.A O.A no hydrogen 2.813 N/A PHE 292.A N VAL 288.A O.B no hydrogen 2.952 N/A LYS 293.A N GLU 289.A O no hydrogen 2.993 N/A LEU 294.A N ALA 290.A O no hydrogen 2.891 N/A PHE 295.A N GLN 291.A O no hydrogen 2.942 N/A ASN 296.A N PHE 292.A O no hydrogen 2.987 N/A SER 297.A N LYS 293.A O no hydrogen 2.956 N/A SER 297.A OG LYS 293.A O no hydrogen 3.152 N/A TRP 298.A N LEU 294.A O no hydrogen 2.885 N/A TYR 299.A N PHE 295.A O no hydrogen 2.921 N/A TYR 299.A OH HIS 218.A ND1 no hydrogen 3.023 N/A ALA 300.A N ASN 296.A O no hydrogen 3.080 N/A ASP 301.A N SER 297.A O no hydrogen 3.226 N/A TRP 302.A N TRP 298.A O no hydrogen 2.762 N/A TRP 302.A NE1 GLU 239.A OE1 no hydrogen 3.044 N/A SER 303.A N TYR 299.A O no hydrogen 2.846 N/A SER 303.A OG TYR 299.A O no hydrogen 2.709 N/A