Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2hph_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 3.A N ASP 33.A O no hydrogen 2.821 N/A ARG 4.A NE LYS 58.A O no hydrogen 3.032 N/A ARG 4.A NH2 LYS 58.A O no hydrogen 2.864 N/A ILE 5.A N GLN 35.A O no hydrogen 2.869 N/A GLY 6.A N ALA 62.A O no hydrogen 2.964 N/A VAL 7.A N LEU 37.A O no hydrogen 2.924 N/A THR 8.A N ALA 64.A O no hydrogen 3.027 N/A ILE 9.A N ASN 39.A O no hydrogen 2.914 N/A TYR 10.A N ASN 66.A OD1 no hydrogen 2.866 N/A TYR 10.A OH ASP 14.A OD1 no hydrogen 2.635 N/A LYS 11.A NZ.A TYR 10.A OH no hydrogen 3.426 N/A TYR 12.A N ASP 40.A OD1 no hydrogen 2.917 N/A ASP 14.A N LYS 11.A O no hydrogen 3.160 N/A MET 17.A N ASP 14.A OD2 no hydrogen 2.869 N/A SER 18.A N ASP 14.A O no hydrogen 2.832 N/A VAL 19.A N ASN 15.A O no hydrogen 3.376 N/A VAL 20.A N PHE 16.A O no hydrogen 3.075 N/A ARG 21.A N MET 17.A O no hydrogen 2.771 N/A ARG 21.A NH1 GLU 25.A OE1 no hydrogen 2.760 N/A LYS 22.A N SER 18.A O no hydrogen 3.054 N/A ALA 23.A N VAL 19.A O no hydrogen 3.006 N/A ILE 24.A N VAL 20.A O no hydrogen 2.893 N/A GLU 25.A N ARG 21.A O no hydrogen 3.152 N/A GLN 26.A N LYS 22.A O no hydrogen 3.060 N/A ASP 27.A N ALA 23.A O no hydrogen 2.969 N/A ALA 28.A N ILE 24.A O no hydrogen 2.955 N/A LYS 29.A N GLU 25.A O no hydrogen 3.001 N/A LYS 29.A NZ GLN 26.A OE1 no hydrogen 2.712 N/A ALA 30.A N ASP 27.A O no hydrogen 3.148 N/A ALA 31.A N ALA 28.A O no hydrogen 2.892 N/A VAL 34.A N ALA 31.A O no hydrogen 2.946 N/A GLN 35.A N THR 3.A O no hydrogen 2.799 N/A LEU 37.A N ILE 5.A O no hydrogen 2.906 N/A ASN 39.A N VAL 7.A O no hydrogen 2.902 N/A SER 41.A N ILE 9.A O no hydrogen 3.004 N/A SER 41.A OG GLN 51.A OE1 no hydrogen 2.761 N/A GLN 42.A N ASP 40.A OD1 no hydrogen 3.010 N/A ASN 43.A N TYR 10.A O no hydrogen 2.802 N/A ASP 44.A N SER 41.A O no hydrogen 3.112 N/A GLN 45.A NE2 GLN 48.A OE1 no hydrogen 2.987 N/A GLN 45.A NE2 ASN 49.A OD1 no hydrogen 2.949 N/A SER 46.A OG.A ASP 44.A OD1 no hydrogen 2.553 N/A LYS 47.A N ASP 44.A OD1 no hydrogen 3.261 N/A LYS 47.A NZ GLN 42.A OE1 no hydrogen 2.790 N/A GLN 48.A N ASP 44.A O no hydrogen 2.995 N/A GLN 48.A NE2 SER 41.A OG no hydrogen 3.040 N/A GLN 48.A NE2 ASN 66.A O no hydrogen 2.889 N/A ASN 49.A N GLN 45.A O no hydrogen 2.812 N/A ASP 50.A N SER 46.A O no hydrogen 3.183 N/A GLN 51.A N LYS 47.A O no hydrogen 2.925 N/A GLN 51.A NE2 ASP 40.A O no hydrogen 2.870 N/A ILE 52.A N GLN 48.A O no hydrogen 2.865 N/A ASP 53.A N ASN 49.A O no hydrogen 3.096 N/A VAL 54.A N ASP 50.A O no hydrogen 3.046 N/A LEU 55.A N GLN 51.A O no hydrogen 2.923 N/A LEU 56.A N ILE 52.A O no hydrogen 2.897 N/A ALA 57.A N ASP 53.A O no hydrogen 2.893 N/A LYS 58.A N VAL 54.A O no hydrogen 2.996 N/A GLY 59.A N LEU 56.A O no hydrogen 2.990 N/A VAL 60.A N LEU 55.A O no hydrogen 3.394 N/A LYS 61.A N ARG 4.A O no hydrogen 2.862 N/A LEU 63.A N PRO 86.A O no hydrogen 2.981 N/A ALA 64.A N GLY 6.A O no hydrogen 2.788 N/A ILE 65.A N VAL 88.A O no hydrogen 2.909 N/A ASN 66.A N THR 8.A O no hydrogen 2.980 N/A ASN 66.A ND2 PHE 90.A O no hydrogen 2.981 N/A ASN 66.A ND2 ASN 91.A OD1 no hydrogen 2.967 N/A VAL 68.A N GLN 45.A OE1 no hydrogen 2.976 N/A ASP 69.A N GLN 45.A OE1 no hydrogen 2.875 N/A ALA 71.A N ASP 69.A OD1 no hydrogen 3.118 N/A ALA 72.A N ASP 69.A O no hydrogen 2.843 N/A ALA 73.A N PRO 70.A O no hydrogen 3.174 N/A VAL 76.A N ALA 72.A O no hydrogen 3.101 N/A ILE 77.A N ALA 73.A O no hydrogen 2.804 N/A GLU 78.A N GLY 74.A O no hydrogen 2.966 N/A LYS 79.A N THR 75.A O no hydrogen 3.223 N/A LYS 79.A NZ ASP 53.A OD1 no hydrogen 2.908 N/A LYS 79.A NZ ASP 53.A OD2 no hydrogen 3.224 N/A ALA 80.A N VAL 76.A O no hydrogen 2.957 N/A ARG 81.A N ILE 77.A O no hydrogen 2.776 N/A ARG 81.A NE GLU 78.A OE1 no hydrogen 2.860 N/A ARG 81.A NH1 GLU 78.A OE2 no hydrogen 2.872 N/A ARG 81.A NH1 SER 101.A O no hydrogen 2.869 N/A ARG 81.A NH2 SER 101.A O no hydrogen 3.431 N/A GLY 82.A N GLU 78.A O no hydrogen 3.179 N/A GLN 83.A N ALA 80.A O no hydrogen 3.086 N/A ASN 84.A N ARG 81.A O no hydrogen 2.906 N/A VAL 85.A N ALA 80.A O no hydrogen 2.958 N/A VAL 87.A N LYS 104.A O no hydrogen 2.932 N/A VAL 88.A N LEU 63.A O no hydrogen 2.840 N/A PHE 89.A N TYR 106.A O no hydrogen 2.862 N/A PHE 90.A N ILE 65.A O no hydrogen 2.957 N/A ASN 91.A N VAL 108.A O no hydrogen 3.118 N/A LYS 92.A N PHE 90.A O no hydrogen 2.893 N/A LYS 92.A NZ VAL 68.A O no hydrogen 2.825 N/A LYS 92.A NZ GLU 149.A OE1 no hydrogen 2.840 N/A LYS 92.A NZ GLU 149.A OE2 no hydrogen 3.412 N/A ARG 96.A NE ASP 100.A OD2 no hydrogen 3.263 N/A ARG 96.A NH1 ASN 288.A O no hydrogen 3.069 N/A ARG 96.A NH2 ASP 100.A OD1 no hydrogen 2.870 N/A ARG 96.A NH2 ASN 288.A O no hydrogen 2.901 N/A ALA 98.A N SER 95.A OG no hydrogen 2.892 N/A LEU 99.A N SER 95.A O no hydrogen 2.920 N/A ASP 100.A N ARG 96.A O no hydrogen 2.898 N/A SER 101.A N ALA 98.A O no hydrogen 3.034 N/A SER 101.A OG ALA 98.A O no hydrogen 2.654 N/A TYR 102.A OH VAL 85.A O no hydrogen 2.669 N/A LYS 104.A NZ ASN 84.A O no hydrogen 2.997 N/A LYS 104.A NZ ASN 84.A OD1 no hydrogen 2.971 N/A ALA 105.A N TYR 102.A O no hydrogen 3.081 N/A TYR 106.A N VAL 87.A O no hydrogen 2.937 N/A TYR 107.A N LYS 289.A O no hydrogen 2.967 N/A VAL 108.A N PHE 89.A O no hydrogen 2.873 N/A GLY 109.A N VAL 291.A O no hydrogen 2.890 N/A THR 110.A OG1 TYR 295.A OH no hydrogen 2.688 N/A SER 112.A OG ASP 154.A OD1 no hydrogen 2.630 N/A LYS 113.A NZ ASP 111.A OD1 no hydrogen 2.743 N/A LYS 113.A NZ ASP 111.A OD2 no hydrogen 3.453 N/A GLU 114.A N ASP 111.A O no hydrogen 2.971 N/A SER 115.A N SER 112.A O no hydrogen 3.107 N/A SER 115.A OG SER 112.A O no hydrogen 2.730 N/A ILE 117.A N LYS 113.A O no hydrogen 2.949 N/A ILE 118.A N GLU 114.A O no hydrogen 2.908 N/A GLN 119.A N SER 115.A O no hydrogen 2.928 N/A GLN 119.A NE2 ALA 209.A O no hydrogen 3.021 N/A GLN 119.A NE2 GLY 234.A O no hydrogen 3.026 N/A GLY 120.A N GLY 116.A O no hydrogen 2.886 N/A ASP 121.A N ILE 117.A O no hydrogen 2.889 N/A LEU 122.A N ILE 118.A O no hydrogen 2.899 N/A ILE 123.A N GLN 119.A O no hydrogen 2.898 N/A ALA 124.A N GLY 120.A O no hydrogen 2.872 N/A LYS 125.A N ASP 121.A O no hydrogen 2.961 N/A LYS 125.A NZ ASP 299.A OD2 no hydrogen 2.774 N/A HIS 126.A N LEU 122.A O no hydrogen 2.983 N/A HIS 126.A NE2 ASP 299.A OD2 no hydrogen 2.721 N/A TRP 127.A N ILE 123.A O no hydrogen 2.788 N/A ALA 128.A N ALA 124.A O no hydrogen 3.018 N/A ALA 129.A N LYS 125.A O no hydrogen 3.085 N/A ASN 130.A N TRP 127.A O no hydrogen 3.190 N/A ASN 130.A ND2 HIS 126.A O no hydrogen 2.854 N/A TRP 133.A N ASN 130.A O no hydrogen 2.887 N/A ASP 134.A N GLN 131.A O no hydrogen 3.088 N/A ASN 136.A N GLU 205.A OE2 no hydrogen 3.251 N/A ASN 136.A ND2 ASP 138.A OD2 no hydrogen 2.999 N/A LYS 137.A N ASP 134.A O no hydrogen 2.978 N/A ASP 138.A N ASP 134.A OD1 no hydrogen 3.348 N/A GLY 139.A N ASP 134.A OD2 no hydrogen 2.773 N/A GLN 140.A N ASP 138.A OD1 no hydrogen 2.874 N/A GLN 140.A NE2.B ASP 138.A OD2 no hydrogen 3.231 N/A ILE 141.A N LYS 172.A O no hydrogen 2.867 N/A GLN 142.A N GLU 205.A OE1 no hydrogen 3.007 N/A GLN 142.A NE2 ASP 138.A OD2 no hydrogen 2.884 N/A GLN 142.A NE2 GLU 174.A OE1 no hydrogen 2.806 N/A PHE 143.A N GLU 174.A O no hydrogen 2.981 N/A VAL 144.A N VAL 206.A O no hydrogen 3.097 N/A LEU 145.A N GLN 177.A O no hydrogen 3.006 N/A LEU 146.A N ILE 208.A O no hydrogen 2.875 N/A LYS 147.A N ASP 179.A O no hydrogen 2.883 N/A LYS 147.A NZ GLU 156.A OE1 no hydrogen 3.033 N/A LYS 147.A NZ GLU 156.A OE2 no hydrogen 3.129 N/A GLY 148.A N ASN 210.A OD1 no hydrogen 2.842 N/A GLY 151.A N GLU 156.A OE2 no hydrogen 2.802 N/A HIS 152.A N GLU 149.A O no hydrogen 3.019 N/A ASP 154.A N HIS 152.A ND1 no hydrogen 3.004 N/A GLU 156.A N HIS 152.A O no hydrogen 2.946 N/A ALA 157.A N PRO 153.A O no hydrogen 3.031 N/A ARG 158.A N ASP 154.A O no hydrogen 2.898 N/A ARG 158.A NE SER 115.A OG no hydrogen 2.878 N/A ARG 158.A NH1 ASN 210.A O no hydrogen 2.848 N/A ARG 158.A NH2 TYR 295.A OH no hydrogen 2.854 N/A THR 159.A N ALA 155.A O no hydrogen 3.094 N/A THR 159.A OG1 ALA 155.A O no hydrogen 2.776 N/A THR 159.A OG1 ASN 210.A OD1 no hydrogen 3.078 N/A THR 160.A N GLU 156.A O no hydrogen 3.034 N/A THR 160.A OG1 GLU 156.A O no hydrogen 3.141 N/A TYR 161.A N ALA 157.A O no hydrogen 2.844 N/A VAL 162.A N ARG 158.A O no hydrogen 3.171 N/A LYS 164.A N THR 160.A O no hydrogen 3.036 N/A GLU 165.A N TYR 161.A O no hydrogen 2.899 N/A LEU 166.A N VAL 162.A O no hydrogen 3.138 N/A ASN 167.A N ILE 163.A O no hydrogen 2.860 N/A ASP 168.A N LYS 164.A O no hydrogen 2.785 N/A LYS 169.A N GLU 165.A O no hydrogen 3.049 N/A LYS 169.A N LEU 166.A O no hydrogen 3.158 N/A LYS 169.A NZ ASP 121.A OD1 no hydrogen 3.173 N/A GLY 170.A N ASN 167.A O no hydrogen 3.016 N/A ILE 171.A N LEU 166.A O no hydrogen 2.986 N/A THR 173.A OG1 ASN 167.A OD1 no hydrogen 3.005 N/A GLU 174.A N ILE 141.A O no hydrogen 2.832 N/A LEU 176.A N PHE 143.A O no hydrogen 2.833 N/A ASP 179.A N LEU 145.A O no hydrogen 3.177 N/A THR 180.A N ASP 179.A OD1 no hydrogen 2.807 N/A THR 180.A OG1 LYS 147.A O no hydrogen 3.175 N/A THR 180.A OG1 GLY 148.A O no hydrogen 2.728 N/A ALA 181.A N LYS 147.A O no hydrogen 2.898 N/A MET 182.A N THR 180.A OG1 no hydrogen 3.039 N/A ASP 184.A N ALA 181.A O no hydrogen 2.909 N/A THR 185.A OG1 ALA 213.A O no hydrogen 2.796 N/A GLN 187.A N ASP 184.A OD2 no hydrogen 2.917 N/A ALA 188.A N ASP 184.A O no hydrogen 3.091 N/A LYS 189.A N THR 185.A O no hydrogen 2.871 N/A ASP 190.A N ALA 186.A O no hydrogen 3.071 N/A LYS 191.A N GLN 187.A O no hydrogen 2.981 N/A LYS 191.A NZ ASP 179.A OD2 no hydrogen 3.009 N/A MET 192.A N ALA 188.A O no hydrogen 2.872 N/A ASP 193.A N LYS 189.A O no hydrogen 2.908 N/A ALA 194.A N ASP 190.A O no hydrogen 3.041 N/A TRP 195.A N LYS 191.A O no hydrogen 3.007 N/A LEU 196.A N MET 192.A O no hydrogen 2.933 N/A SER 197.A N ALA 194.A O no hydrogen 2.983 N/A SER 197.A OG ASP 193.A O no hydrogen 2.809 N/A SER 197.A OG ASP 193.A OD1 no hydrogen 3.193 N/A GLY 198.A N TRP 195.A O no hydrogen 3.502 N/A ALA 201.A N GLY 198.A O no hydrogen 3.302 N/A LYS 203.A N ASN 200.A O no hydrogen 3.041 N/A ILE 204.A N ALA 201.A O no hydrogen 3.187 N/A GLU 205.A N GLN 142.A O no hydrogen 2.836 N/A VAL 206.A N GLN 142.A O no hydrogen 3.222 N/A VAL 207.A N PRO 231.A O no hydrogen 2.929 N/A ILE 208.A N VAL 144.A O no hydrogen 2.898 N/A ALA 209.A N PHE 233.A O no hydrogen 2.860 N/A ASN 210.A N LEU 146.A O no hydrogen 2.907 N/A ASN 210.A ND2 THR 159.A OG1 no hydrogen 3.024 N/A ASN 211.A ND2 TRP 183.A O no hydrogen 3.175 N/A ASP 212.A N VAL 235.A O no hydrogen 2.785 N/A MET 214.A N ASN 211.A OD1 no hydrogen 2.881 N/A ALA 215.A N ASN 211.A O no hydrogen 3.055 N/A MET 216.A N ASP 212.A O no hydrogen 2.793 N/A GLY 217.A N ALA 213.A O no hydrogen 3.214 N/A ALA 218.A N MET 214.A O no hydrogen 3.018 N/A VAL 219.A N ALA 215.A O no hydrogen 2.860 N/A GLU 220.A N MET 216.A O no hydrogen 3.141 N/A ALA 221.A N GLY 217.A O no hydrogen 3.049 N/A LEU 222.A N ALA 218.A O no hydrogen 2.869 N/A LYS 223.A N VAL 219.A O no hydrogen 3.006 N/A ALA 224.A N GLU 220.A O no hydrogen 3.046 N/A HIS 225.A N ALA 221.A O no hydrogen 3.174 N/A HIS 225.A NE2 ASP 193.A OD1 no hydrogen 2.778 N/A ASN 226.A N LYS 223.A O no hydrogen 3.078 N/A LYS 227.A N LEU 222.A O no hydrogen 2.851 N/A ILE 230.A N LYS 227.A O no hydrogen 3.056 N/A PHE 233.A N VAL 207.A O no hydrogen 2.983 N/A GLY 234.A N GLY 252.A O no hydrogen 2.995 N/A ASP 236.A N VAL 254.A O no hydrogen 2.631 N/A ALA 237.A N THR 253.A OG1 no hydrogen 3.304 N/A LEU 238.A N ASP 212.A OD2 no hydrogen 3.032 N/A LEU 242.A N LEU 238.A O no hydrogen 2.873 N/A ALA 243.A N PRO 239.A O no hydrogen 3.015 N/A VAL 245.A N ALA 241.A O no hydrogen 2.925 N/A LYS 246.A N LEU 242.A O no hydrogen 3.018 N/A SER 247.A N ALA 243.A O no hydrogen 3.022 N/A SER 247.A OG LEU 244.A O no hydrogen 3.181 N/A GLY 248.A N VAL 245.A O no hydrogen 3.183 N/A ALA 249.A N SER 247.A OG no hydrogen 3.308 N/A LEU 250.A N LEU 244.A O no hydrogen 3.041 N/A ALA 251.A N VAL 232.A O no hydrogen 2.837 N/A THR 253.A N VAL 298.A O no hydrogen 2.886 N/A THR 253.A OG1 ASP 212.A OD1 no hydrogen 2.607 N/A THR 253.A OG1 ASP 212.A OD2 no hydrogen 3.280 N/A VAL 254.A N THR 253.A OG1 no hydrogen 2.718 N/A LEU 255.A N VAL 296.A O no hydrogen 2.690 N/A ASN 256.A N ASP 236.A O no hydrogen 3.040 N/A ASN 256.A ND2 ASP 236.A OD1 no hydrogen 3.142 N/A ASN 260.A N ASP 257.A OD1 no hydrogen 3.015 N/A ASN 260.A ND2 ASP 257.A OD2 no hydrogen 2.831 N/A GLN 261.A N ASP 257.A O no hydrogen 3.139 N/A GLN 261.A NE2 ASN 256.A OD1 no hydrogen 2.753 N/A GLN 261.A NE2 ASP 257.A O no hydrogen 3.171 N/A ALA 262.A N ALA 258.A O no hydrogen 2.879 N/A LYS 263.A N ASN 259.A O no hydrogen 2.997 N/A LYS 263.A NZ ASP 267.A OD2 no hydrogen 3.310 N/A ALA 264.A N ASN 260.A O no hydrogen 2.927 N/A THR 265.A N GLN 261.A O no hydrogen 2.980 N/A THR 265.A OG1 GLN 261.A O no hydrogen 2.794 N/A PHE 266.A N ALA 262.A O no hydrogen 2.935 N/A ASP 267.A N LYS 263.A O no hydrogen 2.839 N/A LEU 268.A N ALA 264.A O no hydrogen 2.985 N/A ALA 269.A N THR 265.A O no hydrogen 2.955 N/A LYS 270.A N PHE 266.A O no hydrogen 2.888 N/A LYS 270.A NZ ASP 33.A OD2 no hydrogen 3.297 N/A LYS 270.A NZ ASP 274.A OD2 no hydrogen 2.853 N/A ASN 271.A N ASP 267.A O no hydrogen 3.061 N/A ASN 271.A ND2 ALA 278.A O no hydrogen 2.886 N/A ASN 271.A ND2 ASP 280.A O no hydrogen 2.834 N/A LEU 272.A N LEU 268.A O no hydrogen 2.887 N/A ALA 273.A N ALA 269.A O no hydrogen 2.865 N/A ASP 274.A N LYS 270.A O no hydrogen 3.079 N/A GLY 275.A N LEU 272.A O no hydrogen 2.988 N/A LYS 276.A N ASN 271.A O no hydrogen 2.937 N/A GLY 277.A N ASP 280.A OD2 no hydrogen 3.036 N/A ASP 280.A N GLY 277.A O no hydrogen 3.079 N/A THR 282.A N ALA 279.A O no hydrogen 2.909 N/A THR 282.A OG1 ALA 279.A O no hydrogen 2.672 N/A TRP 284.A N THR 282.A OG1 no hydrogen 3.146 N/A TRP 284.A NE1 ASP 267.A OD2 no hydrogen 2.871 N/A ASP 287.A N VAL 290.A O no hydrogen 2.883 N/A LYS 289.A NZ LEU 99.A O no hydrogen 2.637 N/A LYS 289.A NZ ALA 105.A O no hydrogen 2.801 N/A VAL 290.A N ASP 287.A O no hydrogen 3.075 N/A VAL 291.A N TYR 107.A O no hydrogen 2.891 N/A ARG 292.A NH1 GLU 93.A OE1 no hydrogen 2.917 N/A ARG 292.A NH1 GLU 93.A OE2 no hydrogen 3.454 N/A ARG 292.A NH1 THR 110.A O no hydrogen 2.819 N/A ARG 292.A NH2 GLU 93.A OE2 no hydrogen 2.840 N/A VAL 293.A N GLY 109.A O no hydrogen 2.850 N/A TYR 295.A N GLU 114.A OE1 no hydrogen 2.904 N/A TYR 295.A OH THR 110.A OG1 no hydrogen 2.688 N/A VAL 296.A N LEU 255.A O no hydrogen 3.318 N/A VAL 298.A N THR 253.A O no hydrogen 2.858 N/A ASP 299.A N ASN 302.A OD1 no hydrogen 2.885 N/A ASP 301.A N ASP 299.A OD1 no hydrogen 2.989 N/A ASN 302.A N ASP 299.A O no hydrogen 3.288 N/A ASN 302.A ND2 GLY 297.A O no hydrogen 2.875 N/A GLU 305.A N ASN 302.A O no hydrogen 2.788 N/A