Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2htb_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 5.A N SER 1.A O no hydrogen 3.307 N/A LYS 6.A N HIS 2.A O no hydrogen 2.765 N/A ILE 7.A N MET 3.A O no hydrogen 3.184 N/A PHE 8.A N ILE 4.A O no hydrogen 3.226 N/A ALA 9.A N ASN 5.A O no hydrogen 3.131 N/A ALA 9.A N LYS 6.A O no hydrogen 3.328 N/A LEU 10.A N ILE 7.A O no hydrogen 2.915 N/A ILE 13.A N ARG 22.A O no hydrogen 2.807 N/A GLU 14.A N ARG 22.A O no hydrogen 3.149 N/A LEU 16.A N LEU 20.A O no hydrogen 2.654 N/A THR 17.A N LEU 20.A O no hydrogen 3.106 N/A THR 17.A OG1 GLU 112.A OE1 no hydrogen 2.631 N/A THR 17.A OG1 GLU 112.A OE2 no hydrogen 3.436 N/A VAL 19.A N THR 17.A OG1 no hydrogen 2.989 N/A LEU 20.A N THR 17.A O no hydrogen 3.178 N/A LEU 20.A N THR 17.A OG1 no hydrogen 3.042 N/A SER 21.A N VAL 32.A O no hydrogen 3.206 N/A ARG 22.A N GLU 14.A O no hydrogen 3.008 N/A ARG 22.A NH1 GLU 14.A OE2 no hydrogen 2.614 N/A ARG 22.A NH2 ASP 29.A OD1 no hydrogen 2.767 N/A ARG 23.A N LEU 30.A O no hydrogen 3.024 N/A ARG 23.A NE SER 21.A OG no hydrogen 3.245 N/A ARG 23.A NH1 PHE 8.A O no hydrogen 2.842 N/A ARG 23.A NH1 LEU 10.A O no hydrogen 2.768 N/A LEU 25.A N LEU 28.A O no hydrogen 3.285 N/A ASP 27.A N PHE 69.A O no hydrogen 3.189 N/A LEU 28.A N LEU 25.A O no hydrogen 2.887 N/A LEU 30.A N ARG 23.A O no hydrogen 2.797 N/A ILE 31.A N PHE 42.A O no hydrogen 2.815 N/A VAL 32.A N SER 21.A O no hydrogen 2.798 N/A VAL 33.A N ALA 40.A O no hydrogen 2.582 N/A ASP 34.A N VAL 19.A O no hydrogen 3.091 N/A HIS 35.A N VAL 38.A O no hydrogen 2.853 N/A VAL 38.A N HIS 35.A O no hydrogen 2.892 N/A LYS 39.A N LYS 53.A O no hydrogen 2.874 N/A LYS 39.A NZ ASP 34.A OD1 no hydrogen 3.011 N/A ALA 40.A N VAL 33.A O no hydrogen 2.934 N/A SER 41.A N SER 51.A O no hydrogen 3.063 N/A SER 41.A OG SER 51.A OG no hydrogen 2.873 N/A PHE 42.A N ILE 31.A O no hydrogen 2.761 N/A ALA 43.A N HIS 48.A O no hydrogen 2.801 N/A LEU 44.A N ASP 29.A O no hydrogen 3.279 N/A GLN 45.A NE2 LYS 70.A O no hydrogen 3.431 N/A GLY 46.A N LEU 103.A O no hydrogen 2.709 N/A ALA 47.A N LEU 44.A O no hydrogen 3.016 N/A HIS 48.A N ALA 43.A O no hydrogen 2.812 N/A HIS 48.A NE2 GLY 77.A O no hydrogen 2.614 N/A LEU 50.A N SER 41.A O no hydrogen 2.562 N/A SER 51.A N SER 41.A O no hydrogen 3.091 N/A SER 51.A OG SER 41.A OG no hydrogen 2.873 N/A TRP 52.A NE1 GLY 146.A O no hydrogen 3.061 N/A LYS 53.A N LYS 39.A O no hydrogen 2.844 N/A VAL 55.A N GLN 37.A O no hydrogen 2.889 N/A GLU 57.A N PRO 54.A O no hydrogen 3.076 N/A VAL 60.A N TRP 52.A O no hydrogen 2.975 N/A TRP 62.A N TYR 168.A O no hydrogen 2.764 N/A SER 64.A N ARG 76.A O no hydrogen 3.139 N/A SER 64.A OG ASP 256.A O no hydrogen 2.713 N/A ASN 66.A N SER 64.A OG no hydrogen 2.822 N/A ASN 66.A ND2 ASN 65.A O no hydrogen 3.684 N/A THR 67.A N SER 64.A O no hydrogen 3.199 N/A THR 67.A OG1 PRO 68.A O no hydrogen 3.057 N/A LYS 70.A NZ ASP 26.A OD2 no hydrogen 3.312 N/A THR 71.A N ASP 27.A OD2 no hydrogen 2.793 N/A THR 71.A OG1 ASP 27.A OD2 no hydrogen 3.244 N/A GLY 72.A N GLN 45.A OE1 no hydrogen 2.763 N/A VAL 73.A N LYS 70.A O no hydrogen 3.072 N/A ARG 76.A N THR 67.A OG1 no hydrogen 2.795 N/A ARG 76.A NE ASP 256.A OD1 no hydrogen 3.158 N/A ARG 76.A NE ASP 256.A OD2 no hydrogen 3.093 N/A ARG 76.A NH1 TYR 168.A OH no hydrogen 2.995 N/A ARG 76.A NH2 ASP 256.A OD1 no hydrogen 3.256 N/A ARG 76.A NH2 ASP 256.A OD2 no hydrogen 3.359 N/A GLY 78.A N TRP 62.A O no hydrogen 2.782 N/A VAL 79.A N LEU 49.A O no hydrogen 2.806 N/A CYS 82.A N ALA 164.A O no hydrogen 3.005 N/A CYS 82.A SG PRO 80.A O no hydrogen 3.950 N/A TRP 85.A NE1 PRO 95.A O no hydrogen 2.854 N/A GLY 87.A N HIS 97.A ND1 no hydrogen 2.676 N/A LEU 94.A N GLN 91.A O no hydrogen 3.162 N/A HIS 97.A N GLY 87.A O no hydrogen 3.008 N/A PHE 99.A N TRP 83.A O no hydrogen 2.910 N/A ALA 100.A N TRP 83.A O no hydrogen 3.128 N/A ARG 101.A NH2 SER 96.A O no hydrogen 2.859 N/A ASN 102.A N PHE 99.A O no hydrogen 2.893 N/A ASN 102.A ND2 GLY 72.A O no hydrogen 2.714 N/A TRP 105.A N LEU 44.A O no hydrogen 2.856 N/A TRP 105.A NE1 ALA 100.A O no hydrogen 3.228 N/A ALA 106.A N GLU 122.A O no hydrogen 2.884 N/A LYS 108.A N THR 120.A O no hydrogen 2.745 N/A ALA 109.A N THR 120.A O no hydrogen 3.238 N/A ASN 111.A N MET 118.A O no hydrogen 3.206 N/A ASP 113.A N GLY 116.A O no hydrogen 3.105 N/A VAL 117.A N VAL 145.A O no hydrogen 2.929 N/A MET 118.A N ASN 111.A O no hydrogen 2.856 N/A LEU 119.A N PHE 143.A O no hydrogen 2.936 N/A THR 120.A N ALA 109.A O no hydrogen 2.736 N/A PHE 121.A N ALA 141.A O no hydrogen 2.752 N/A GLU 122.A N ALA 106.A O no hydrogen 2.782 N/A LEU 123.A N LEU 139.A O no hydrogen 2.949 N/A GLN 124.A NE2 THR 138.A OG1 no hydrogen 2.836 N/A SER 125.A N PHE 137.A O no hydrogen 2.930 N/A SER 125.A OG PHE 137.A O no hydrogen 3.428 N/A SER 126.A OG THR 129.A OG1 no hydrogen 3.154 N/A THR 129.A N SER 126.A OG no hydrogen 3.006 N/A THR 129.A OG1 SER 126.A OG no hydrogen 3.154 N/A ARG 130.A N SER 126.A O no hydrogen 2.926 N/A ARG 130.A NH1 ASP 136.A OD1 no hydrogen 3.350 N/A LYS 131.A N ALA 128.A O no hydrogen 3.409 N/A TYR 132.A N THR 129.A O no hydrogen 3.401 N/A TRP 133.A N THR 129.A O no hydrogen 3.148 N/A HIS 135.A N TRP 133.A O no hydrogen 2.769 N/A PHE 137.A N SER 125.A OG no hydrogen 3.108 N/A THR 138.A N HIS 156.A O no hydrogen 3.017 N/A LEU 139.A N LEU 123.A O no hydrogen 2.774 N/A LEU 140.A N GLU 154.A O no hydrogen 2.825 N/A ALA 141.A N PHE 121.A O no hydrogen 3.044 N/A ARG 142.A N GLU 152.A O no hydrogen 2.678 N/A ARG 142.A NH2 GLU 154.A OE2 no hydrogen 2.810 N/A PHE 143.A N LEU 119.A O no hydrogen 2.916 N/A LYS 144.A N GLU 150.A O no hydrogen 2.859 N/A VAL 145.A N VAL 117.A O no hydrogen 2.854 N/A GLY 146.A N THR 148.A O no hydrogen 2.845 N/A CYS 149.A N ILE 291.A O no hydrogen 2.989 N/A GLU 150.A N LYS 144.A O no hydrogen 2.834 N/A ILE 151.A N GLN 289.A O no hydrogen 2.946 N/A LEU 153.A N LEU 287.A O no hydrogen 2.854 N/A GLU 154.A N LEU 140.A O no hydrogen 2.687 N/A ALA 155.A N SER 285.A O no hydrogen 2.861 N/A HIS 156.A N THR 138.A O no hydrogen 2.842 N/A HIS 156.A NE2 GLU 154.A OE1 no hydrogen 2.453 N/A THR 161.A N GLN 277.A O no hydrogen 2.963 N/A THR 162.A N PRO 84.A O no hydrogen 2.937 N/A THR 162.A OG1 TYR 272.A O no hydrogen 3.350 N/A SER 163.A N TYR 272.A O no hydrogen 2.813 N/A ALA 164.A N CYS 82.A O no hydrogen 2.986 N/A LEU 165.A N THR 270.A O no hydrogen 2.712 N/A HIS 166.A N PRO 80.A O no hydrogen 2.794 N/A HIS 166.A ND1 HIS 166.A O no hydrogen 2.556 N/A TYR 168.A N GLY 78.A O no hydrogen 2.891 N/A PHE 169.A N VAL 266.A O no hydrogen 2.863 N/A ASN 170.A N VAL 60.A O no hydrogen 2.597 N/A ASN 170.A ND2 GLU 59.A O no hydrogen 2.947 N/A VAL 171.A N THR 264.A O no hydrogen 3.090 N/A GLY 172.A N ASP 224.A OD2 no hydrogen 2.881 N/A ILE 174.A N LYS 263.A O no hydrogen 2.575 N/A ALA 175.A N ASP 173.A OD1 no hydrogen 2.862 N/A ASN 176.A N ASP 173.A O no hydrogen 2.714 N/A ASN 176.A ND2 THR 226.A OG1 no hydrogen 2.230 N/A VAL 177.A N ILE 174.A O no hydrogen 3.372 N/A LYS 178.A N HIS 223.A O no hydrogen 3.108 N/A VAL 179.A N GLN 203.A O no hydrogen 2.935 N/A SER 180.A N VAL 221.A O no hydrogen 2.942 N/A SER 180.A OG HIS 223.A NE2 no hydrogen 2.595 N/A LEU 182.A N GLY 201.A O no hydrogen 2.823 N/A ARG 185.A N ASP 184.A OD1 no hydrogen 2.580 N/A PHE 186.A N GLY 196.A O no hydrogen 2.961 N/A ILE 187.A N VAL 212.A O no hydrogen 2.939 N/A ASP 188.A N LYS 194.A O no hydrogen 2.899 N/A LYS 189.A N ASP 210.A O no hydrogen 3.031 N/A VAL 190.A N ASP 188.A OD1 no hydrogen 3.038 N/A ASN 191.A N ASP 188.A O no hydrogen 2.877 N/A ASN 191.A N ASP 188.A OD1 no hydrogen 3.269 N/A ASN 191.A ND2 ASP 188.A OD1 no hydrogen 3.168 N/A ASN 191.A ND2 ASP 188.A OD2 no hydrogen 2.688 N/A LYS 194.A N ASN 191.A O no hydrogen 2.948 N/A GLY 196.A N PHE 186.A O no hydrogen 2.928 N/A LEU 198.A N ASP 184.A O no hydrogen 2.912 N/A ILE 202.A N ASP 200.A OD2 no hydrogen 3.197 N/A GLN 203.A N VAL 179.A O no hydrogen 2.849 N/A ARG 208.A N ASP 207.A OD2 no hydrogen 2.556 N/A THR 209.A N ASN 245.A O no hydrogen 3.066 N/A THR 209.A OG1 ASP 207.A O no hydrogen 2.724 N/A ARG 211.A N GLY 243.A O no hydrogen 2.914 N/A VAL 212.A N ILE 187.A O no hydrogen 3.029 N/A TYR 213.A N VAL 241.A O no hydrogen 2.716 N/A LEU 214.A N ARG 185.A O no hydrogen 3.107 N/A GLU 217.A N GLY 181.A O no hydrogen 3.005 N/A CYS 219.A SG SER 220.A O no hydrogen 3.532 N/A CYS 219.A SG VAL 233.A O no hydrogen 3.993 N/A SER 220.A N VAL 233.A O no hydrogen 2.603 N/A SER 220.A OG HIS 235.A NE2 no hydrogen 2.699 N/A VAL 221.A N SER 180.A O no hydrogen 3.039 N/A ILE 222.A N ILE 231.A O no hydrogen 2.767 N/A HIS 223.A N LYS 178.A O no hydrogen 2.802 N/A HIS 223.A NE2 SER 180.A OG no hydrogen 2.595 N/A ASP 224.A N ARG 229.A O no hydrogen 2.932 N/A ALA 225.A N ASN 176.A O no hydrogen 3.362 N/A THR 226.A N ASP 224.A OD1 no hydrogen 2.844 N/A LEU 227.A N ASP 224.A OD1 no hydrogen 3.115 N/A ARG 229.A N ASP 224.A O no hydrogen 3.018 N/A ARG 229.A NH1 GLU 58.A O no hydrogen 3.015 N/A ARG 229.A NH1 GLU 59.A O no hydrogen 3.414 N/A ARG 229.A NH2 GLU 59.A O no hydrogen 2.826 N/A ARG 229.A NH2 ASN 170.A O no hydrogen 2.788 N/A THR 230.A N ALA 294.A O no hydrogen 2.967 N/A ILE 231.A N ILE 222.A O no hydrogen 2.895 N/A ASP 232.A N CYS 292.A O no hydrogen 2.676 N/A VAL 233.A N SER 220.A O no hydrogen 2.627 N/A VAL 234.A N THR 290.A O no hydrogen 2.804 N/A HIS 235.A N ALA 218.A O no hydrogen 2.824 N/A HIS 235.A ND1 THR 270.A OG1 no hydrogen 2.910 N/A HIS 235.A NE2 SER 220.A OG no hydrogen 2.699 N/A HIS 236.A N ALA 288.A O no hydrogen 2.665 N/A LEU 239.A N VAL 271.A O no hydrogen 3.063 N/A ASN 240.A N VAL 271.A O no hydrogen 3.051 N/A ASN 240.A ND2 THR 274.A OG1 no hydrogen 2.873 N/A VAL 241.A N TYR 213.A O no hydrogen 3.415 N/A VAL 242.A N GLU 269.A O no hydrogen 2.991 N/A GLY 243.A N ARG 211.A O no hydrogen 2.991 N/A TRP 244.A N CYS 267.A O no hydrogen 2.985 N/A ASN 245.A N THR 209.A O no hydrogen 3.082 N/A SER 251.A N GLY 247.A O no hydrogen 2.836 N/A SER 251.A OG PRO 258.A O no hydrogen 2.927 N/A SER 251.A OG ASP 259.A O no hydrogen 3.239 N/A VAL 252.A N PRO 248.A O no hydrogen 3.033 N/A SER 253.A N ALA 249.A O no hydrogen 3.022 N/A SER 253.A OG ALA 249.A O no hydrogen 3.157 N/A MET 254.A N LEU 250.A O no hydrogen 3.063 N/A GLY 261.A N PRO 258.A O no hydrogen 2.900 N/A TYR 262.A N SER 251.A OG no hydrogen 3.209 N/A LYS 263.A N ASP 260.A O no hydrogen 3.049 N/A THR 264.A N GLY 261.A O no hydrogen 3.181 N/A VAL 266.A N PHE 169.A O no hydrogen 3.241 N/A CYS 267.A N TRP 244.A O no hydrogen 2.860 N/A CYS 267.A SG SER 167.A O no hydrogen 3.473 N/A GLU 269.A N VAL 242.A O no hydrogen 2.575 N/A THR 270.A N LEU 165.A O no hydrogen 3.172 N/A THR 270.A OG1 HIS 235.A ND1 no hydrogen 2.910 N/A THR 270.A OG1 GLN 289.A OE1 no hydrogen 2.820 N/A VAL 271.A N ASN 240.A O no hydrogen 3.140 N/A TYR 272.A N SER 163.A O no hydrogen 2.743 N/A ALA 273.A N ASN 240.A OD1 no hydrogen 3.139 N/A THR 274.A N ASN 240.A OD1 no hydrogen 2.895 N/A THR 274.A OG1 ASN 240.A OD1 no hydrogen 3.148 N/A GLN 277.A N THR 161.A O no hydrogen 2.990 N/A GLN 277.A NE2 ARG 286.A O no hydrogen 3.023 N/A ALA 279.A N PHE 159.A O no hydrogen 2.897 N/A THR 280.A N LYS 283.A O no hydrogen 3.116 N/A LYS 283.A N THR 280.A OG1 no hydrogen 2.680 N/A SER 285.A N ALA 155.A O no hydrogen 3.042 N/A LEU 287.A N LEU 153.A O no hydrogen 3.140 N/A ALA 288.A N HIS 236.A O no hydrogen 2.869 N/A GLN 289.A N ILE 151.A O no hydrogen 2.847 N/A GLN 289.A NE2 SER 167.A OG no hydrogen 2.576 N/A THR 290.A N VAL 234.A O no hydrogen 2.730 N/A THR 290.A OG1 HIS 236.A NE2 no hydrogen 3.407 N/A ILE 291.A N CYS 149.A O no hydrogen 2.859 N/A CYS 292.A N ASP 232.A O no hydrogen 3.133 N/A ALA 294.A N THR 230.A O no hydrogen 2.991 N/A LYS 295.A NZ GLY 56.A O no hydrogen 3.417 N/A ARG 296.A N ASN 228.A O no hydrogen 2.475 N/A