Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2hxy_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 2.A OG1 ASP 4.A OD2 no hydrogen 3.197 N/A ASP 4.A N THR 2.A OG1 no hydrogen 3.346 N/A MET 6.A N PHE 3.A O no hydrogen 3.260 N/A ARG 9.A N GLN 61.A OE1 no hydrogen 2.877 N/A ARG 9.A NE ASP 11.A OD1 no hydrogen 3.548 N/A ARG 9.A NH2 ASP 11.A OD2 no hydrogen 3.207 N/A LEU 12.A N ARG 9.A O no hydrogen 3.319 N/A LEU 13.A N ARG 9.A O no hydrogen 3.108 N/A ARG 14.A N GLU 10.A O no hydrogen 2.898 N/A ILE 16.A N LEU 12.A O no hydrogen 2.707 N/A TYR 17.A N LEU 13.A O no hydrogen 3.069 N/A TYR 17.A OH ASP 4.A OD2 no hydrogen 2.915 N/A ALA 18.A N ARG 14.A O no hydrogen 2.768 N/A TYR 19.A N GLY 15.A O no hydrogen 2.644 N/A GLY 20.A N TYR 17.A O no hydrogen 2.821 N/A SER 25.A N GLN 28.A OE1 no hydrogen 2.851 N/A GLN 28.A NE2 THR 49.A O no hydrogen 3.311 N/A GLN 29.A N SER 25.A O no hydrogen 3.251 N/A ARG 30.A NH2 ASP 305.A OD1 no hydrogen 3.330 N/A ALA 31.A N ILE 27.A O no hydrogen 2.995 N/A ILE 32.A N GLN 28.A O no hydrogen 2.884 N/A LYS 33.A N GLN 29.A O no hydrogen 2.683 N/A GLN 34.A N ARG 30.A O no hydrogen 2.636 N/A ILE 35.A N ALA 31.A O no hydrogen 2.812 N/A ILE 36.A N ILE 32.A O no hydrogen 3.021 N/A LYS 37.A N LYS 33.A O no hydrogen 3.186 N/A LYS 37.A NZ GLU 280.A OE2 no hydrogen 3.120 N/A GLY 38.A N GLN 34.A O no hydrogen 3.332 N/A GLY 38.A N ILE 35.A O no hydrogen 2.935 N/A ARG 39.A NE ASP 198.A O no hydrogen 3.372 N/A ILE 42.A N ILE 200.A O no hydrogen 2.854 N/A ALA 43.A N LEU 179.A O no hydrogen 3.047 N/A GLN 44.A N ILE 202.A O no hydrogen 3.032 N/A GLN 44.A NE2 ALA 182.A O no hydrogen 3.377 N/A SER 45.A N SER 181.A O no hydrogen 3.032 N/A THR 54.A N GLY 50.A O no hydrogen 3.295 N/A THR 54.A OG1 GLY 50.A O no hydrogen 3.529 N/A SER 56.A N THR 52.A O no hydrogen 3.009 N/A SER 56.A OG THR 52.A O no hydrogen 2.957 N/A ILE 57.A N ALA 53.A O no hydrogen 2.558 N/A SER 58.A N THR 54.A O no hydrogen 3.416 N/A SER 58.A OG THR 54.A O no hydrogen 3.112 N/A VAL 59.A N PHE 55.A O no hydrogen 2.699 N/A LEU 60.A N SER 56.A O no hydrogen 2.833 N/A GLN 61.A N ILE 57.A O no hydrogen 3.053 N/A CYS 62.A N SER 58.A O no hydrogen 3.248 N/A CYS 62.A SG ILE 36.A O no hydrogen 3.954 N/A LEU 63.A N GLN 61.A O no hydrogen 2.943 N/A VAL 67.A N ASP 64.A O no hydrogen 2.846 N/A THR 70.A OG1 GLN 120.A O no hydrogen 2.758 N/A GLN 71.A N HIS 121.A O no hydrogen 3.038 N/A GLN 71.A NE2 ASP 64.A O no hydrogen 3.035 N/A LEU 73.A N MET 146.A O no hydrogen 2.848 N/A ILE 74.A N VAL 123.A O no hydrogen 2.726 N/A LEU 75.A N VAL 148.A O no hydrogen 2.888 N/A ALA 76.A N GLY 125.A O no hydrogen 3.251 N/A LEU 81.A N THR 78.A OG1 no hydrogen 3.341 N/A ALA 82.A N THR 78.A O no hydrogen 2.751 N/A VAL 83.A N ARG 79.A O no hydrogen 2.982 N/A GLN 84.A N GLU 80.A O no hydrogen 3.068 N/A ILE 85.A N LEU 81.A O no hydrogen 3.017 N/A GLN 86.A N ALA 82.A O no hydrogen 3.297 N/A GLN 86.A NE2 CYS 100.A O no hydrogen 2.862 N/A LYS 87.A N VAL 83.A O no hydrogen 2.761 N/A GLY 88.A N GLN 84.A O no hydrogen 2.733 N/A LEU 89.A N ILE 85.A O no hydrogen 2.836 N/A LEU 90.A N GLN 86.A O no hydrogen 2.834 N/A ALA 91.A N LYS 87.A O no hydrogen 3.037 N/A LEU 92.A N GLY 88.A O no hydrogen 2.827 N/A LEU 92.A N LEU 89.A O no hydrogen 3.091 N/A GLY 93.A N LEU 89.A O no hydrogen 2.964 N/A MET 96.A N GLY 93.A O no hydrogen 2.439 N/A GLN 99.A N HIS 121.A ND1 no hydrogen 3.227 N/A GLN 99.A NE2 ASN 97.A O no hydrogen 3.695 N/A CYS 100.A SG VAL 122.A O no hydrogen 3.653 N/A HIS 101.A N VAL 122.A O no hydrogen 3.036 N/A HIS 101.A NE2 ASP 112.A OD1 no hydrogen 2.907 N/A CYS 103.A N ALA 124.A O no hydrogen 2.733 N/A ILE 104.A N ASP 112.A OD2 no hydrogen 3.129 N/A VAL 109.A N GLY 106.A O no hydrogen 3.383 N/A ASP 112.A N ASN 108.A O no hydrogen 2.695 N/A ILE 113.A N VAL 109.A O no hydrogen 2.963 N/A ARG 114.A N GLY 110.A O no hydrogen 2.784 N/A LYS 115.A N GLU 111.A O no hydrogen 2.987 N/A LYS 115.A NZ HIS 101.A ND1 no hydrogen 3.566 N/A LEU 116.A N ASP 112.A O no hydrogen 3.137 N/A ASP 117.A N ILE 113.A O no hydrogen 3.302 N/A GLY 119.A N LYS 115.A O no hydrogen 3.254 N/A GLN 120.A NE2 LYS 115.A O no hydrogen 3.559 N/A HIS 121.A NE2 ILE 65.A O no hydrogen 2.853 N/A VAL 123.A N ALA 72.A O no hydrogen 3.064 N/A ALA 124.A N HIS 101.A O no hydrogen 2.968 N/A GLY 125.A N ILE 74.A O no hydrogen 3.194 N/A ARG 129.A NH2 ASP 132.A OD1 no hydrogen 3.151 N/A VAL 130.A N THR 126.A O no hydrogen 2.918 N/A PHE 131.A N PRO 127.A O no hydrogen 3.017 N/A ASP 132.A N GLY 128.A O no hydrogen 3.035 N/A MET 133.A N ARG 129.A O no hydrogen 3.090 N/A ILE 134.A N VAL 130.A O no hydrogen 3.223 N/A ILE 134.A N PHE 131.A O no hydrogen 2.955 N/A ARG 135.A N PHE 131.A O no hydrogen 2.791 N/A ARG 136.A N ASP 132.A O no hydrogen 2.744 N/A ARG 136.A NE ASP 132.A OD1 no hydrogen 3.488 N/A ARG 137.A N ILE 134.A O no hydrogen 3.118 N/A SER 138.A N MET 133.A O no hydrogen 2.982 N/A SER 138.A OG ARG 136.A O no hydrogen 3.391 N/A LEU 139.A N MET 133.A O no hydrogen 2.690 N/A THR 141.A OG1 TYR 170.A O no hydrogen 3.000 N/A ILE 144.A N THR 141.A O no hydrogen 2.478 N/A LYS 145.A N GLN 71.A O no hydrogen 2.778 N/A LYS 145.A NZ GLN 71.A OE1 no hydrogen 3.469 N/A LEU 147.A N GLN 176.A O no hydrogen 2.739 N/A VAL 148.A N LEU 73.A O no hydrogen 2.819 N/A LEU 149.A N VAL 178.A O no hydrogen 3.044 N/A ASP 150.A N LEU 75.A O no hydrogen 3.099 N/A ALA 152.A N ILE 180.A O no hydrogen 3.023 N/A MET 155.A N GLU 151.A O no hydrogen 3.053 N/A LEU 156.A N ALA 152.A O no hydrogen 3.094 N/A ASN 157.A N ASP 153.A O no hydrogen 3.351 N/A LYS 158.A N GLU 154.A O no hydrogen 3.057 N/A GLY 159.A N LEU 156.A O no hydrogen 2.605 N/A PHE 160.A N MET 155.A O no hydrogen 3.170 N/A ILE 164.A N PHE 160.A O no hydrogen 3.018 N/A TYR 165.A N LYS 161.A O no hydrogen 3.229 N/A ASP 166.A N GLU 162.A O no hydrogen 2.828 N/A VAL 167.A N GLN 163.A O no hydrogen 2.899 N/A TYR 168.A N ILE 164.A O no hydrogen 3.046 N/A ARG 169.A N TYR 165.A O no hydrogen 3.229 N/A TYR 170.A N ASP 166.A O no hydrogen 3.354 N/A LEU 171.A N VAL 167.A O no hydrogen 3.308 N/A LEU 171.A N TYR 168.A O no hydrogen 2.735 N/A THR 175.A OG1 PRO 172.A O no hydrogen 3.206 N/A GLN 176.A NE2 ILE 35.A O no hydrogen 2.689 N/A GLN 176.A NE2 ARG 39.A O no hydrogen 2.938 N/A VAL 177.A N ASP 40.A OD1 no hydrogen 3.297 N/A VAL 178.A N LEU 147.A O no hydrogen 2.898 N/A LEU 179.A N VAL 41.A O no hydrogen 2.733 N/A ILE 180.A N LEU 149.A O no hydrogen 3.025 N/A SER 181.A N ALA 43.A O no hydrogen 3.057 N/A SER 181.A OG ASP 153.A OD1 no hydrogen 2.970 N/A SER 181.A OG THR 183.A O no hydrogen 2.500 N/A HIS 186.A N HIS 186.A ND1 no hydrogen 2.535 N/A ILE 188.A N PRO 185.A O no hydrogen 3.115 N/A LEU 189.A N PRO 185.A O no hydrogen 3.426 N/A MET 191.A N ILE 188.A O no hydrogen 3.267 N/A THR 192.A N ILE 188.A O no hydrogen 2.792 N/A THR 192.A OG1 ILE 188.A O no hydrogen 3.245 N/A THR 192.A OG1 LEU 189.A O no hydrogen 2.565 N/A ASN 193.A N LEU 189.A O no hydrogen 3.022 N/A LYS 194.A N MET 191.A O no hydrogen 2.980 N/A PHE 195.A N THR 192.A O no hydrogen 3.220 N/A THR 197.A N ASP 40.A OD2 no hydrogen 3.119 N/A ILE 200.A N ASP 40.A O no hydrogen 2.665 N/A ILE 202.A N ILE 42.A O no hydrogen 2.886 N/A VAL 204.A N GLN 44.A OE1 no hydrogen 3.102 N/A ARG 206.A NH1 GLU 208.A OE2 no hydrogen 2.660 N/A THR 210.A N ARG 330.A O no hydrogen 3.208 N/A ILE 214.A N LEU 211.A O no hydrogen 3.129 N/A LYS 215.A N GLY 338.A O no hydrogen 3.150 N/A PHE 217.A N ALA 340.A O no hydrogen 2.948 N/A PHE 218.A N ASP 364.A O no hydrogen 2.719 N/A VAL 219.A N ASN 342.A O no hydrogen 2.706 N/A VAL 221.A N VAL 219.A O no hydrogen 2.713 N/A GLU 225.A N GLU 225.A OE1 no hydrogen 2.661 N/A TRP 226.A N ARG 223.A O no hydrogen 3.140 N/A LYS 227.A N GLU 224.A O no hydrogen 2.831 N/A LYS 227.A NZ GLU 224.A OE1 no hydrogen 3.098 N/A LYS 227.A NZ GLU 224.A OE2 no hydrogen 3.369 N/A LYS 227.A NZ TYR 315.A O no hydrogen 3.169 N/A LYS 227.A NZ ASP 316.A OD2 no hydrogen 2.798 N/A THR 230.A N TRP 226.A O no hydrogen 3.333 N/A THR 230.A OG1 TRP 226.A O no hydrogen 3.181 N/A LEU 231.A N LYS 227.A O no hydrogen 2.892 N/A LEU 231.A N PHE 228.A O no hydrogen 2.700 N/A CYS 232.A N PHE 228.A O no hydrogen 3.016 N/A CYS 232.A SG PHE 228.A O no hydrogen 3.733 N/A ASP 233.A N ASP 229.A O no hydrogen 2.895 N/A TYR 235.A N LEU 231.A O no hydrogen 2.700 N/A THR 237.A N LEU 234.A O no hydrogen 2.911 N/A LEU 238.A N TYR 235.A O no hydrogen 3.033 N/A THR 239.A N TYR 235.A O no hydrogen 3.299 N/A THR 239.A OG1 TYR 235.A O no hydrogen 3.260 N/A THR 241.A N LEU 238.A O no hydrogen 2.740 N/A THR 241.A OG1 GLN 242.A O no hydrogen 2.879 N/A THR 241.A OG1 SER 310.A OG no hydrogen 3.194 N/A GLN 242.A NE2 PHE 286.A O no hydrogen 2.440 N/A GLN 242.A NE2 SER 291.A O no hydrogen 2.485 N/A VAL 244.A N LEU 311.A O no hydrogen 3.255 N/A ILE 245.A N LEU 294.A O no hydrogen 2.671 N/A PHE 246.A N ILE 313.A O no hydrogen 2.868 N/A CYS 247.A SG PHE 246.A O no hydrogen 2.862 N/A CYS 247.A SG LYS 252.A O no hydrogen 3.987 N/A ASN 248.A ND2 LEU 317.A O no hydrogen 3.559 N/A LYS 252.A N THR 249.A O no hydrogen 3.010 N/A LYS 252.A NZ GLU 224.A OE1 no hydrogen 2.628 N/A LYS 252.A NZ GLU 224.A OE2 no hydrogen 3.054 N/A LYS 252.A NZ ASP 316.A OD1 no hydrogen 3.325 N/A LYS 252.A NZ ASP 316.A OD2 no hydrogen 3.251 N/A VAL 253.A N THR 249.A O no hydrogen 3.128 N/A VAL 253.A N LYS 250.A O no hydrogen 2.747 N/A ASP 254.A N LYS 250.A O no hydrogen 3.067 N/A TRP 255.A N ARG 251.A O no hydrogen 2.898 N/A LEU 256.A N LYS 252.A O no hydrogen 3.183 N/A THR 257.A N VAL 253.A O no hydrogen 2.660 N/A THR 257.A OG1 VAL 253.A O no hydrogen 3.080 N/A GLU 258.A N ASP 254.A O no hydrogen 2.996 N/A LYS 259.A N TRP 255.A O no hydrogen 2.782 N/A MET 260.A N THR 257.A O no hydrogen 2.721 N/A ARG 261.A N THR 257.A O no hydrogen 2.815 N/A ARG 261.A NE VAL 267.A O no hydrogen 3.314 N/A ARG 261.A NH2 VAL 267.A O no hydrogen 3.004 N/A GLU 262.A N GLU 258.A O no hydrogen 2.839 N/A ASN 264.A N ARG 261.A O no hydrogen 3.110 N/A SER 268.A N VAL 293.A O no hydrogen 3.021 N/A SER 268.A OG SER 291.A OG no hydrogen 3.410 N/A MET 270.A N ILE 295.A O no hydrogen 3.382 N/A GLU 278.A N PRO 275.A O no hydrogen 2.736 N/A ARG 279.A N PRO 275.A O no hydrogen 2.807 N/A ILE 282.A N GLU 278.A O no hydrogen 2.956 N/A ILE 282.A N ARG 279.A O no hydrogen 2.959 N/A MET 283.A N ARG 279.A O no hydrogen 3.258 N/A LYS 284.A N GLU 280.A O no hydrogen 3.092 N/A PHE 286.A N ILE 282.A O no hydrogen 2.910 N/A ARG 287.A N MET 283.A O no hydrogen 2.605 N/A ARG 287.A NE ASP 198.A OD1 no hydrogen 3.120 N/A ARG 287.A NH2 ASP 198.A OD1 no hydrogen 2.823 N/A SER 288.A N LYS 284.A O no hydrogen 2.956 N/A GLY 289.A N GLU 285.A O no hydrogen 3.206 N/A ALA 290.A N GLU 285.A O no hydrogen 3.099 N/A SER 291.A OG SER 268.A OG no hydrogen 3.410 N/A ARG 292.A NH1 THR 239.A O no hydrogen 3.438 N/A LEU 294.A N ALA 243.A O no hydrogen 2.849 N/A ILE 295.A N SER 268.A O no hydrogen 2.828 N/A SER 296.A N ILE 245.A O no hydrogen 2.818 N/A SER 296.A OG THR 297.A O no hydrogen 2.872 N/A THR 297.A N MET 270.A O no hydrogen 3.463 N/A VAL 306.A N LEU 304.A O no hydrogen 2.608 N/A ILE 312.A N VAL 339.A O no hydrogen 2.917 N/A ILE 313.A N VAL 244.A O no hydrogen 2.871 N/A ASN 314.A N ILE 341.A O no hydrogen 3.065 N/A ASN 314.A ND2 ASN 342.A OD1 no hydrogen 2.485 N/A GLU 322.A N ASN 320.A O no hydrogen 2.559 N/A LEU 323.A N ASN 320.A O no hydrogen 3.318 N/A TYR 324.A OH GLN 216.A OE1 no hydrogen 2.645 N/A ILE 325.A N TYR 359.A OH no hydrogen 3.322 N/A ARG 327.A N LEU 323.A O no hydrogen 2.930 N/A ARG 327.A NE ASN 314.A OD1 no hydrogen 3.035 N/A ARG 327.A NH2 ASN 314.A OD1 no hydrogen 3.094 N/A ILE 328.A N TYR 324.A O no hydrogen 3.253 N/A GLY 329.A N ILE 325.A O no hydrogen 2.700 N/A ARG 330.A NH1 GLU 212.A O no hydrogen 2.781 N/A SER 331.A OG ASP 207.A OD2 no hydrogen 2.560 N/A TYR 334.A N SER 331.A OG no hydrogen 3.158 N/A GLY 335.A N GLY 332.A O no hydrogen 3.048 N/A VAL 339.A N SER 310.A O no hydrogen 2.878 N/A ALA 340.A N LYS 215.A O no hydrogen 3.067 N/A ILE 341.A N ILE 312.A O no hydrogen 2.957 N/A ASN 342.A N PHE 217.A O no hydrogen 2.485 N/A ASN 342.A ND2 PHE 217.A O no hydrogen 3.125 N/A ASN 342.A ND2 TYR 324.A OH no hydrogen 2.960 N/A PHE 343.A N ASN 314.A O no hydrogen 3.126 N/A LYS 345.A NZ GLU 224.A OE1 no hydrogen 3.021 N/A ASN 346.A N GLU 222.A O no hydrogen 3.388 N/A ASP 348.A N LYS 345.A O no hydrogen 2.524 N/A ILE 349.A N ASN 346.A O no hydrogen 3.290 N/A LEU 352.A N ASP 348.A O no hydrogen 2.877 N/A ARG 353.A N ILE 349.A O no hydrogen 3.396 N/A ARG 353.A NH2 GLN 357.A OE1 no hydrogen 3.137 N/A ASP 354.A N ARG 350.A O no hydrogen 3.128 N/A ILE 355.A N ILE 351.A O no hydrogen 3.149 N/A GLU 356.A N LEU 352.A O no hydrogen 2.981 N/A GLN 357.A N ARG 353.A O no hydrogen 2.738 N/A TYR 358.A N ASP 354.A O no hydrogen 2.805 N/A TYR 358.A OH GLU 322.A OE1 no hydrogen 2.701 N/A TYR 359.A N ILE 355.A O no hydrogen 3.146 N/A THR 361.A N GLU 356.A O no hydrogen 3.125 N/A GLN 362.A NE2 ASP 364.A OD1 no hydrogen 2.830 N/A GLN 362.A NE2 ASP 364.A OD2 no hydrogen 3.108 N/A ILE 363.A N GLU 356.A OE1 no hydrogen 2.680 N/A ASP 364.A N GLN 216.A O no hydrogen 3.057 N/A MET 366.A N PHE 218.A O no hydrogen 3.125 N/A LEU 373.A N VAL 370.A O no hydrogen 2.844 N/A