Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2hz4_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 4.A N VAL 66.A O no hydrogen 3.120 N/A ARG 6.A NH1 PRO 72.A O no hydrogen 3.034 N/A THR 7.A N GLU 5.A OE2 no hydrogen 2.994 N/A THR 7.A OG1 GLU 5.A OE2 no hydrogen 2.757 N/A ASP 8.A N GLU 5.A O no hydrogen 3.024 N/A ILE 9.A N ARG 6.A O no hydrogen 3.156 N/A THR 10.A N VAL 22.A O no hydrogen 2.886 N/A LYS 12.A N GLU 20.A O no hydrogen 2.980 N/A HIS 13.A ND1 LYS 14.A O no hydrogen 3.145 N/A TYR 19.A N VAL 32.A O no hydrogen 2.854 N/A TYR 19.A OH GLU 17.A OE1 no hydrogen 2.752 N/A GLU 20.A N HIS 13.A O no hydrogen 2.980 N/A GLY 21.A N VAL 30.A O no hydrogen 2.849 N/A VAL 22.A N THR 10.A O no hydrogen 2.884 N/A TRP 23.A N LEU 28.A O no hydrogen 2.846 N/A LYS 24.A N ASP 8.A O no hydrogen 2.804 N/A LYS 24.A NZ THR 7.A O no hydrogen 2.778 N/A TYR 26.A N TRP 23.A O no hydrogen 2.952 N/A SER 27.A N LYS 24.A O no hydrogen 3.406 N/A VAL 30.A N GLY 21.A O no hydrogen 2.892 N/A ALA 31.A N THR 77.A O no hydrogen 2.893 N/A VAL 32.A N TYR 19.A O no hydrogen 2.866 N/A LYS 33.A N ILE 75.A O no hydrogen 2.773 N/A THR 34.A N GLU 17.A O no hydrogen 2.731 N/A THR 34.A OG1 PHE 73.A O no hydrogen 3.347 N/A LEU 35.A N PHE 73.A O no hydrogen 3.009 N/A THR 39.A OG1 LYS 36.A O no hydrogen 2.918 N/A GLU 41.A N THR 39.A O no hydrogen 2.993 N/A PHE 45.A N GLU 41.A O no hydrogen 2.814 N/A LEU 46.A N VAL 42.A O no hydrogen 3.289 N/A LYS 47.A N GLU 43.A O no hydrogen 3.301 N/A LYS 47.A NZ LYS 47.A O no hydrogen 3.115 N/A ALA 49.A N PHE 45.A O no hydrogen 3.157 N/A ALA 50.A N LEU 46.A O no hydrogen 2.884 N/A VAL 51.A N LYS 47.A O no hydrogen 3.006 N/A MET 52.A N GLU 48.A O no hydrogen 3.028 N/A LYS 53.A N ALA 49.A O no hydrogen 3.102 N/A GLU 54.A N VAL 51.A O no hydrogen 2.844 N/A ILE 55.A N MET 52.A O no hydrogen 3.333 N/A LYS 56.A N TYR 115.A OH no hydrogen 3.174 N/A ASN 59.A N HIS 57.A ND1 no hydrogen 3.141 N/A ASN 59.A ND2 VAL 139.A O no hydrogen 3.006 N/A LEU 60.A N HIS 57.A O no hydrogen 3.088 N/A VAL 61.A N VAL 141.A O no hydrogen 2.930 N/A GLN 62.A N GLU 78.A OE2 no hydrogen 2.969 N/A LEU 64.A N ILE 76.A O no hydrogen 3.023 N/A GLY 65.A N ILE 76.A O no hydrogen 3.209 N/A VAL 66.A N TRP 2.A O no hydrogen 3.074 N/A CYS 67.A N TYR 74.A O no hydrogen 2.798 N/A CYS 67.A SG MET 4.A O no hydrogen 3.866 N/A THR 68.A N GLU 3.A OE2 no hydrogen 2.716 N/A THR 68.A OG1 GLU 3.A OE2 no hydrogen 2.410 N/A TYR 74.A N CYS 67.A O no hydrogen 3.005 N/A ILE 75.A N LYS 33.A O no hydrogen 2.773 N/A ILE 76.A N GLY 65.A O no hydrogen 2.762 N/A THR 77.A N ALA 31.A O no hydrogen 2.813 N/A THR 77.A OG1 GLU 78.A O no hydrogen 3.381 N/A GLU 78.A N GLN 62.A O no hydrogen 3.055 N/A TYR 82.A N VAL 133.A O no hydrogen 3.093 N/A GLY 83.A N MET 80.A O no hydrogen 3.028 N/A ASN 84.A ND2 ASP 87.A OD2 no hydrogen 2.810 N/A LEU 85.A N CYS 131.A O no hydrogen 2.683 N/A ASP 87.A N ASN 84.A OD1 no hydrogen 3.197 N/A TYR 88.A N ASN 84.A O no hydrogen 2.922 N/A LEU 89.A N LEU 85.A O no hydrogen 2.945 N/A ARG 90.A N LEU 86.A O no hydrogen 3.172 N/A ARG 90.A NE GLY 198.A O no hydrogen 2.846 N/A ARG 90.A NH2 GLY 198.A O no hydrogen 3.206 N/A GLU 91.A N ASP 87.A O no hydrogen 3.102 N/A GLU 91.A N TYR 88.A O no hydrogen 3.251 N/A CYS 92.A SG LEU 89.A O no hydrogen 3.396 N/A GLU 96.A N ASN 93.A O no hydrogen 3.253 N/A GLU 96.A N ASN 93.A OD1 no hydrogen 3.059 N/A VAL 97.A N ASN 93.A O no hydrogen 3.103 N/A VAL 101.A N ASN 98.A OD1 no hydrogen 3.141 N/A LEU 102.A N ASN 98.A O no hydrogen 3.070 N/A LEU 103.A N ALA 99.A O no hydrogen 3.309 N/A TYR 104.A N VAL 100.A O no hydrogen 3.147 N/A MET 105.A N VAL 101.A O no hydrogen 3.147 N/A ALA 106.A N LEU 102.A O no hydrogen 3.093 N/A THR 107.A N LEU 103.A O no hydrogen 2.936 N/A THR 107.A OG1 LEU 103.A O no hydrogen 2.575 N/A GLN 108.A N TYR 104.A O no hydrogen 2.793 N/A GLN 108.A NE2 TYR 104.A O no hydrogen 3.345 N/A GLN 108.A NE2 HIS 137.A O no hydrogen 2.918 N/A ILE 109.A N MET 105.A O no hydrogen 3.004 N/A SER 110.A N ALA 106.A O no hydrogen 3.022 N/A SER 110.A OG ALA 106.A O no hydrogen 2.908 N/A SER 110.A OG THR 107.A O no hydrogen 2.736 N/A SER 110.A OG HIS 252.A ND1 no hydrogen 3.243 N/A SER 111.A N THR 107.A O no hydrogen 3.079 N/A SER 111.A OG HIS 57.A NE2 no hydrogen 3.367 N/A ALA 112.A N GLN 108.A O no hydrogen 3.171 N/A MET 113.A N ILE 109.A O no hydrogen 3.247 N/A MET 113.A N SER 110.A O no hydrogen 3.029 N/A GLU 114.A N SER 110.A O no hydrogen 2.908 N/A TYR 115.A N SER 111.A O no hydrogen 3.231 N/A LEU 116.A N ALA 112.A O no hydrogen 3.119 N/A GLU 117.A N MET 113.A O no hydrogen 2.754 N/A LYS 118.A N GLU 114.A O no hydrogen 2.990 N/A LYS 118.A N TYR 115.A O no hydrogen 2.962 N/A LYS 119.A N TYR 115.A O no hydrogen 3.125 N/A LYS 119.A NZ GLU 54.A O no hydrogen 2.845 N/A ASN 120.A N GLU 117.A O no hydrogen 3.467 N/A ASN 120.A ND2 MET 150.A O no hydrogen 2.533 N/A ASN 120.A ND2 GLY 152.A O no hydrogen 3.537 N/A PHE 121.A N LEU 116.A O no hydrogen 2.859 N/A ILE 122.A N ARG 148.A O no hydrogen 3.136 N/A HIS 123.A N ASP 183.A OD2 no hydrogen 2.755 N/A HIS 123.A NE2 ALA 142.A O no hydrogen 2.810 N/A ARG 124.A N ASP 183.A OD1 no hydrogen 3.340 N/A ARG 124.A N ASP 183.A OD2 no hydrogen 3.300 N/A ARG 124.A NE LEU 146.A O no hydrogen 3.059 N/A ARG 124.A NH2 LEU 146.A O no hydrogen 3.189 N/A ASP 125.A N HIS 123.A ND1 no hydrogen 3.229 N/A ALA 128.A N GLU 193.A OE2 no hydrogen 2.976 N/A ASN 130.A N ALA 127.A O no hydrogen 2.843 N/A ASN 130.A ND2 ASP 125.A O no hydrogen 2.852 N/A ASN 130.A ND2 ASP 125.A OD2 no hydrogen 2.847 N/A CYS 131.A N ALA 128.A O no hydrogen 3.057 N/A CYS 131.A SG ALA 127.A O no hydrogen 3.859 N/A LEU 132.A N LYS 140.A O no hydrogen 2.992 N/A VAL 133.A N GLY 83.A O no hydrogen 2.801 N/A GLY 134.A N LEU 138.A O no hydrogen 3.012 N/A VAL 139.A N GLN 108.A OE1 no hydrogen 2.738 N/A LYS 140.A N LEU 132.A O no hydrogen 2.980 N/A LYS 140.A NZ PRO 58.A O no hydrogen 3.395 N/A LYS 140.A NZ GLU 78.A OE1 no hydrogen 3.029 N/A LYS 140.A NZ GLU 78.A OE2 no hydrogen 2.727 N/A VAL 141.A N ASN 59.A O no hydrogen 2.892 N/A ALA 142.A N ASN 130.A O no hydrogen 3.142 N/A SER 147.A N PHE 144.A O no hydrogen 2.914 N/A SER 147.A OG HIS 123.A O no hydrogen 3.537 N/A SER 147.A OG PHE 144.A O no hydrogen 2.991 N/A ARG 148.A N ILE 122.A O no hydrogen 3.270 N/A ARG 148.A NH1 GLY 145.A O no hydrogen 3.363 N/A ARG 148.A NH1 SER 147.A O no hydrogen 2.762 N/A ARG 148.A NH2 GLU 44.A OE2 no hydrogen 3.338 N/A MET 150.A N ASN 120.A O no hydrogen 3.103 N/A TYR 155.A N PHE 178.A O no hydrogen 3.081 N/A ALA 157.A N ASN 176.A O no hydrogen 2.978 N/A ALA 161.A N HIS 158.A O no hydrogen 3.046 N/A LYS 166.A NZ PRO 201.A O no hydrogen 3.095 N/A LYS 166.A NZ ILE 205.A O no hydrogen 2.839 N/A TRP 167.A N PRO 164.A O no hydrogen 3.127 N/A TRP 167.A NE1 GLU 193.A OE2 no hydrogen 3.096 N/A THR 168.A N ILE 165.A O no hydrogen 2.688 N/A THR 168.A OG1 PRO 164.A O no hydrogen 2.700 N/A GLU 171.A N GLU 171.A OE1 no hydrogen 2.615 N/A SER 172.A N ALA 169.A O no hydrogen 2.940 N/A SER 172.A OG LYS 177.A O no hydrogen 2.730 N/A LEU 173.A N ALA 169.A O no hydrogen 3.065 N/A ALA 174.A N PRO 170.A O no hydrogen 2.959 N/A TYR 175.A N GLU 171.A O no hydrogen 3.010 N/A LYS 177.A N GLU 171.A O no hydrogen 3.363 N/A PHE 178.A N TYR 155.A O no hydrogen 2.820 N/A SER 179.A N SER 182.A OG no hydrogen 3.035 N/A LYS 181.A NZ PRO 246.A O no hydrogen 2.886 N/A SER 182.A N SER 179.A OG no hydrogen 3.154 N/A SER 182.A OG SER 179.A O no hydrogen 2.991 N/A ASP 183.A N SER 179.A O no hydrogen 3.303 N/A VAL 184.A N ILE 180.A O no hydrogen 2.900 N/A TRP 185.A N LYS 181.A O no hydrogen 3.077 N/A ALA 186.A N SER 182.A O no hydrogen 3.140 N/A PHE 187.A N ASP 183.A O no hydrogen 2.823 N/A GLY 188.A N VAL 184.A O no hydrogen 2.919 N/A VAL 189.A N TRP 185.A O no hydrogen 3.226 N/A LEU 190.A N ALA 186.A O no hydrogen 3.104 N/A LEU 191.A N PHE 187.A O no hydrogen 2.873 N/A TRP 192.A N GLY 188.A O no hydrogen 3.221 N/A TRP 192.A NE1 GLU 221.A O no hydrogen 3.346 N/A GLU 193.A N VAL 189.A O no hydrogen 2.867 N/A ILE 194.A N LEU 190.A O no hydrogen 2.878 N/A ALA 195.A N LEU 191.A O no hydrogen 2.819 N/A THR 196.A N TRP 192.A O no hydrogen 3.240 N/A THR 196.A OG1 TRP 192.A O no hydrogen 2.802 N/A THR 196.A OG1 GLU 193.A O no hydrogen 3.147 N/A TYR 197.A N ILE 194.A O no hydrogen 3.090 N/A TYR 197.A OH VAL 97.A O no hydrogen 2.935 N/A GLY 198.A N GLU 193.A O no hydrogen 2.704 N/A MET 199.A N THR 196.A OG1 no hydrogen 3.239 N/A ILE 205.A N TYR 202.A O no hydrogen 3.167 N/A SER 208.A OG ASP 206.A OD2 no hydrogen 2.656 N/A GLN 209.A N ASP 206.A O no hydrogen 3.018 N/A GLN 209.A NE2 ASP 206.A OD1 no hydrogen 3.140 N/A GLN 209.A NE2 ASP 206.A OD2 no hydrogen 3.309 N/A VAL 210.A N LEU 207.A O no hydrogen 3.415 N/A LEU 213.A N GLN 209.A O no hydrogen 3.055 N/A LEU 214.A N VAL 210.A O no hydrogen 2.948 N/A GLU 215.A N TYR 211.A O no hydrogen 2.898 N/A LYS 216.A N GLU 212.A O no hydrogen 2.892 N/A ASP 217.A N LEU 214.A O no hydrogen 2.976 N/A TYR 218.A N LEU 213.A O no hydrogen 2.836 N/A ARG 219.A NE TRP 238.A O no hydrogen 3.094 N/A ARG 219.A NH1 LEU 214.A O no hydrogen 3.113 N/A ARG 219.A NH1 TYR 218.A O no hydrogen 2.908 N/A ARG 219.A NH2 TRP 238.A O no hydrogen 3.074 N/A ARG 222.A NH1 CYS 226.A O no hydrogen 3.238 N/A CYS 226.A N PRO 223.A O no hydrogen 3.158 N/A CYS 226.A SG PRO 227.A O no hydrogen 3.400 N/A TYR 231.A N PRO 227.A O no hydrogen 3.177 N/A TYR 231.A OH MET 220.A O no hydrogen 2.836 N/A GLU 232.A N GLU 228.A O no hydrogen 2.826 N/A LEU 233.A N LYS 229.A O no hydrogen 3.180 N/A MET 234.A N VAL 230.A O no hydrogen 2.966 N/A ARG 235.A N TYR 231.A O no hydrogen 2.964 N/A ARG 235.A NE TYR 231.A OH no hydrogen 3.181 N/A ALA 236.A N GLU 232.A O no hydrogen 3.031 N/A CYS 237.A N LEU 233.A O no hydrogen 2.789 N/A CYS 237.A SG VAL 184.A O no hydrogen 3.544 N/A CYS 237.A SG LEU 233.A O no hydrogen 3.427 N/A TRP 238.A N ARG 235.A O no hydrogen 3.194 N/A GLN 239.A N ALA 236.A O no hydrogen 3.318 N/A GLN 239.A NE2 ARG 235.A O no hydrogen 3.447 N/A SER 243.A OG ASN 241.A OD1 no hydrogen 2.829 N/A ASP 244.A N ASN 241.A O no hydrogen 2.767 N/A ARG 245.A N PRO 242.A O no hydrogen 3.165 N/A ARG 245.A NE GLN 239.A O no hydrogen 2.839 N/A ARG 245.A NH1 GLU 171.A OE2 no hydrogen 3.192 N/A ARG 245.A NH1 LYS 181.A O no hydrogen 3.271 N/A ARG 245.A NH2 GLU 171.A OE1 no hydrogen 3.116 N/A ARG 245.A NH2 GLU 171.A OE2 no hydrogen 3.536 N/A ARG 245.A NH2 GLN 239.A O no hydrogen 2.973 N/A ARG 245.A NH2 TRP 240.A O no hydrogen 2.983 N/A PHE 248.A N GLU 117.A OE2 no hydrogen 2.529 N/A ALA 249.A N GLU 117.A OE1 no hydrogen 3.018 N/A GLU 250.A N SER 247.A OG no hydrogen 2.876 N/A ILE 251.A N SER 247.A O no hydrogen 2.901 N/A HIS 252.A N PHE 248.A O no hydrogen 2.863 N/A HIS 252.A ND1 SER 110.A OG no hydrogen 3.243 N/A GLN 253.A N ALA 249.A O no hydrogen 3.075 N/A ALA 254.A N GLU 250.A O no hydrogen 3.121 N/A PHE 255.A N ILE 251.A O no hydrogen 2.899 N/A GLU 256.A N HIS 252.A O no hydrogen 2.619 N/A THR 257.A N GLN 253.A O no hydrogen 3.071 N/A MET 258.A N ALA 254.A O no hydrogen 2.990 N/A PHE 259.A N PHE 255.A O no hydrogen 2.755 N/A GLN 260.A N GLU 256.A O no hydrogen 3.078 N/A GLU 261.A N THR 257.A O no hydrogen 3.306 N/A