Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2i9k_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 1.A N GLY 284.A O no hydrogen 2.778 N/A MET 1.A N ASN 309.A OD1 no hydrogen 3.411 N/A ILE 2.A N GLN 312.A OE1 no hydrogen 2.618 N/A LYS 7.A NZ ILE 4.A O no hydrogen 2.728 N/A LYS 7.A NZ SER 30.A O no hydrogen 3.018 N/A GLN 8.A NE2 ASP 6.A O no hydrogen 2.977 N/A LEU 9.A N CYS 31.A O no hydrogen 2.637 N/A THR 10.A OG1 LYS 7.A O no hydrogen 2.982 N/A LEU 12.A N LEU 9.A O no hydrogen 3.055 N/A ARG 13.A N ASP 73.A OD2 no hydrogen 2.530 N/A ARG 13.A NE ASP 71.A O no hydrogen 2.914 N/A ARG 13.A NH2 ASP 71.A O no hydrogen 2.967 N/A PHE 14.A N GLU 34.A O no hydrogen 2.729 N/A ILE 15.A N ILE 74.A O no hydrogen 2.983 N/A ASP 16.A N TYR 37.A O no hydrogen 2.564 N/A LEU 17.A N CYS 76.A O no hydrogen 3.170 N/A ALA 19.A N ASN 39.A O no hydrogen 2.834 N/A GLY 20.A N GLU 40.A OE1 no hydrogen 2.878 N/A GLY 22.A N ALA 19.A O no hydrogen 2.942 N/A ARG 25.A NE TYR 49.A OH no hydrogen 2.949 N/A ARG 25.A NH1 GLU 29.A OE2 no hydrogen 2.875 N/A ARG 25.A NH2 TYR 49.A OH no hydrogen 3.113 N/A LEU 26.A N GLY 22.A O no hydrogen 2.710 N/A ALA 27.A N GLY 23.A O no hydrogen 3.127 N/A LEU 28.A N PHE 24.A O no hydrogen 2.993 N/A GLU 29.A N ARG 25.A O no hydrogen 2.763 N/A SER 30.A N LEU 26.A O no hydrogen 3.120 N/A SER 30.A N ALA 27.A O no hydrogen 3.133 N/A SER 30.A OG ALA 27.A O no hydrogen 2.466 N/A CYS 31.A N LEU 28.A O no hydrogen 3.014 N/A CYS 31.A SG ALA 27.A O no hydrogen 3.874 N/A GLY 32.A N GLU 29.A O no hydrogen 3.085 N/A ALA 33.A N LEU 28.A O no hydrogen 2.975 N/A GLU 34.A N LEU 12.A O no hydrogen 2.730 N/A CYS 35.A SG PHE 14.A O no hydrogen 3.879 N/A CYS 35.A SG TYR 37.A O no hydrogen 3.537 N/A VAL 36.A N PHE 14.A O no hydrogen 2.958 N/A TYR 37.A OH GLU 58.A OE1 no hydrogen 2.613 N/A ASN 39.A N ASP 16.A O no hydrogen 2.649 N/A ASN 39.A ND2 TYR 37.A OH no hydrogen 2.819 N/A ASN 39.A ND2 GLY 59.A O no hydrogen 3.060 N/A GLU 40.A N GLU 58.A O no hydrogen 3.004 N/A ASP 42.A N GLU 40.A OE2 no hydrogen 2.791 N/A ALA 45.A N ASP 42.A OD1 no hydrogen 2.971 N/A GLN 46.A N ASP 42.A O no hydrogen 2.737 N/A GLN 46.A NE2 GLU 40.A O no hydrogen 2.785 N/A GLU 47.A N LYS 43.A O no hydrogen 2.854 N/A VAL 48.A N TYR 44.A O no hydrogen 3.051 N/A TYR 49.A N ALA 45.A O no hydrogen 2.803 N/A TYR 49.A OH ASP 16.A OD2 no hydrogen 2.937 N/A GLU 50.A N GLN 46.A O no hydrogen 2.945 N/A MET 51.A N GLU 47.A O no hydrogen 2.931 N/A ASN 52.A N TYR 49.A O no hydrogen 2.977 N/A ASN 52.A ND2 VAL 48.A O no hydrogen 2.849 N/A ASN 52.A ND2 LYS 290.A O no hydrogen 2.866 N/A PHE 53.A N TYR 49.A O no hydrogen 2.777 N/A PHE 53.A N GLU 50.A O no hydrogen 3.203 N/A GLY 54.A N GLU 50.A O no hydrogen 2.733 N/A GLU 58.A N SER 38.A O no hydrogen 3.140 N/A THR 62.A N ASP 60.A OD1 no hydrogen 2.731 N/A THR 62.A OG1 ASP 60.A OD1 no hydrogen 2.486 N/A THR 62.A OG1 ASP 60.A OD2 no hydrogen 3.153 N/A GLN 63.A N ASP 60.A O no hydrogen 2.958 N/A VAL 64.A N ILE 61.A O no hydrogen 3.237 N/A GLU 66.A N GLU 66.A OE1 no hydrogen 2.483 N/A LYS 67.A N ASN 65.A OD1 no hydrogen 2.827 N/A THR 68.A N ASN 65.A O no hydrogen 2.569 N/A ILE 69.A N GLU 66.A O no hydrogen 2.700 N/A ASP 73.A N ARG 13.A O no hydrogen 2.589 N/A ILE 74.A N ARG 13.A O no hydrogen 2.955 N/A LEU 75.A N VAL 115.A O no hydrogen 2.715 N/A CYS 76.A N ILE 15.A O no hydrogen 3.046 N/A ALA 77.A N PHE 117.A O no hydrogen 2.802 N/A PHE 84.A N CYS 81.A O no hydrogen 2.807 N/A SER 85.A N CYS 81.A O no hydrogen 2.926 N/A SER 87.A N SER 85.A OG no hydrogen 3.240 N/A SER 87.A OG GLN 237.A OE1 no hydrogen 3.539 N/A GLY 88.A N SER 85.A O no hydrogen 3.335 N/A GLN 90.A NE2 ASN 123.A OD1 no hydrogen 2.930 N/A GLU 94.A N LYS 91.A O no hydrogen 2.915 N/A ASP 95.A N GLY 92.A O no hydrogen 3.038 N/A ARG 97.A N ASP 95.A OD1 no hydrogen 2.490 N/A ARG 97.A NH1 ASP 95.A OD1 no hydrogen 3.456 N/A GLY 98.A N ASP 95.A O no hydrogen 2.895 N/A PHE 102.A N THR 99.A O no hydrogen 2.772 N/A ASP 103.A N LEU 100.A O no hydrogen 2.770 N/A ILE 104.A N LEU 100.A O no hydrogen 3.170 N/A ALA 105.A N PHE 101.A O no hydrogen 2.770 N/A ARG 106.A N PHE 102.A O no hydrogen 3.118 N/A ARG 106.A NE GLU 66.A OE1 no hydrogen 2.844 N/A ARG 106.A NH1 ASP 103.A OD1 no hydrogen 2.659 N/A ARG 106.A NH2 GLU 66.A OE1 no hydrogen 3.179 N/A ILE 107.A N ASP 103.A O no hydrogen 3.244 N/A ILE 107.A N ILE 104.A O no hydrogen 2.691 N/A VAL 108.A N ILE 104.A O no hydrogen 2.931 N/A ARG 109.A N ALA 105.A O no hydrogen 3.217 N/A GLU 110.A N ARG 106.A O no hydrogen 3.236 N/A LYS 111.A N ILE 107.A O no hydrogen 2.832 N/A LYS 111.A NZ ILE 69.A O no hydrogen 2.690 N/A LYS 111.A NZ ASP 71.A OD1 no hydrogen 2.907 N/A LYS 112.A N VAL 108.A O no hydrogen 2.722 N/A VAL 115.A N ASP 73.A O no hydrogen 2.718 N/A VAL 116.A N CYS 170.A O no hydrogen 2.695 N/A PHE 117.A N LEU 75.A O no hydrogen 2.587 N/A MET 118.A N MET 168.A O no hydrogen 2.907 N/A GLU 119.A N ALA 77.A O no hydrogen 2.981 N/A ASN 120.A N ILE 166.A O no hydrogen 3.246 N/A ASN 120.A ND2 PRO 80.A O no hydrogen 2.876 N/A VAL 121.A N ASN 120.A OD1 no hydrogen 2.924 N/A LYS 122.A NZ GLU 164.A OE1 no hydrogen 3.492 N/A ALA 124.A N VAL 121.A O no hydrogen 3.098 N/A ALA 125.A N LYS 122.A O no hydrogen 2.773 N/A SER 126.A N ASN 123.A O no hydrogen 3.242 N/A HIS 127.A N ASN 123.A O no hydrogen 2.813 N/A GLY 130.A N SER 126.A O no hydrogen 2.732 N/A ASN 131.A N ASP 128.A O no hydrogen 2.874 N/A ASN 131.A ND2 ASP 128.A OD2 no hydrogen 3.498 N/A GLU 134.A N GLY 130.A O no hydrogen 3.235 N/A VAL 135.A N ASN 131.A O no hydrogen 2.959 N/A VAL 136.A N THR 132.A O no hydrogen 3.124 N/A LYS 137.A N LEU 133.A O no hydrogen 2.819 N/A ASN 138.A N GLU 134.A O no hydrogen 2.780 N/A THR 139.A N VAL 135.A O no hydrogen 2.661 N/A THR 139.A OG1 VAL 135.A O no hydrogen 2.595 N/A MET 140.A N VAL 136.A O no hydrogen 2.925 N/A MET 140.A N LYS 137.A O no hydrogen 3.130 N/A ASN 141.A N LYS 137.A O no hydrogen 2.840 N/A GLU 142.A N ASN 138.A O no hydrogen 2.721 N/A LEU 143.A N MET 140.A O no hydrogen 3.038 N/A ASP 144.A N ASN 141.A O no hydrogen 2.727 N/A TYR 145.A N MET 140.A O no hydrogen 3.095 N/A TYR 145.A OH PRO 113.A O no hydrogen 2.539 N/A SER 146.A N PHE 171.A O no hydrogen 2.879 N/A SER 146.A OG HIS 148.A NE2 no hydrogen 3.210 N/A HIS 148.A N ILE 169.A O no hydrogen 2.964 N/A LYS 150.A N TYR 167.A O no hydrogen 2.996 N/A LEU 152.A N ARG 165.A O no hydrogen 2.920 N/A ALA 154.A N ARG 163.A O no hydrogen 3.033 N/A LEU 155.A N ASN 153.A OD1 no hydrogen 3.482 N/A ASP 156.A N ASN 153.A O no hydrogen 2.857 N/A TYR 157.A N ALA 154.A O no hydrogen 2.626 N/A TYR 157.A OH PRO 183.A O no hydrogen 3.001 N/A GLN 161.A N ILE 159.A O no hydrogen 2.835 N/A LYS 162.A N ALA 248.A O no hydrogen 2.731 N/A LYS 162.A NZ LYS 162.A O no hydrogen 2.690 N/A LYS 162.A NZ GLU 164.A OE2 no hydrogen 3.469 N/A ARG 163.A NE GLN 161.A OE1 no hydrogen 2.973 N/A ARG 163.A NH1 GLY 303.A O no hydrogen 3.537 N/A ARG 163.A NH2 GLY 303.A O no hydrogen 2.835 N/A ARG 165.A N LEU 152.A O no hydrogen 2.969 N/A ARG 165.A NH1 GLU 164.A O no hydrogen 2.957 N/A ILE 166.A N ASN 120.A O no hydrogen 2.890 N/A TYR 167.A N LYS 150.A O no hydrogen 2.706 N/A MET 168.A N MET 118.A O no hydrogen 2.977 N/A ILE 169.A N HIS 148.A O no hydrogen 2.608 N/A CYS 170.A N VAL 116.A O no hydrogen 2.833 N/A CYS 170.A SG VAL 116.A O no hydrogen 3.857 N/A PHE 171.A N SER 146.A OG no hydrogen 3.280 N/A ARG 172.A N LYS 114.A O no hydrogen 3.048 N/A ARG 172.A NE LYS 112.A O no hydrogen 3.089 N/A ARG 172.A NH1 ASP 174.A OD2 no hydrogen 2.403 N/A ASN 173.A N ASP 144.A O no hydrogen 2.799 N/A PHE 186.A N ASP 156.A O no hydrogen 3.157 N/A THR 190.A OG1 ASN 189.A OD1 no hydrogen 2.972 N/A PHE 191.A N ASP 194.A OD2 no hydrogen 3.012 N/A VAL 192.A N GLY 246.A O no hydrogen 3.388 N/A LYS 193.A N THR 244.A O no hydrogen 2.927 N/A LYS 193.A NZ ASP 194.A OD1 no hydrogen 2.567 N/A LYS 193.A NZ ASP 194.A OD2 no hydrogen 3.159 N/A ASP 194.A N PHE 191.A O no hydrogen 2.835 N/A LEU 195.A N VAL 192.A O no hydrogen 2.816 N/A LEU 196.A N VAL 192.A O no hydrogen 3.161 N/A LEU 197.A N GLU 278.A OE2 no hydrogen 2.651 N/A GLU 201.A N PRO 198.A O no hydrogen 2.824 N/A VAL 202.A N ASP 199.A O no hydrogen 3.044 N/A LEU 205.A N VAL 202.A O no hydrogen 2.910 N/A VAL 206.A N GLU 203.A O no hydrogen 2.863 N/A ILE 207.A N THR 271.A O no hydrogen 2.809 N/A ARG 209.A NE ASP 211.A OD1 no hydrogen 3.201 N/A ARG 209.A NH2 ASP 211.A OD2 no hydrogen 2.749 N/A LEU 212.A N ARG 209.A O no hydrogen 2.818 N/A VAL 213.A N ILE 231.A O no hydrogen 2.730 N/A THR 215.A N LEU 229.A O no hydrogen 2.631 N/A THR 215.A OG1 LEU 229.A O no hydrogen 2.867 N/A ASN 216.A ND2 THR 215.A OG1 no hydrogen 3.081 N/A ILE 219.A N GLU 218.A OE1 no hydrogen 2.698 N/A GLN 221.A N GLU 220.A OE1 no hydrogen 2.363 N/A THR 223.A N ARG 245.A O no hydrogen 3.121 N/A LEU 229.A N ILE 241.A O no hydrogen 2.743 N/A GLY 230.A N ILE 241.A O no hydrogen 3.404 N/A ILE 231.A N VAL 213.A O no hydrogen 2.989 N/A VAL 232.A N GLU 239.A O no hydrogen 3.109 N/A GLY 233.A N ASP 211.A OD2 no hydrogen 2.912 N/A GLY 235.A N VAL 232.A O no hydrogen 2.983 N/A GLY 236.A N GLU 239.A OE1 no hydrogen 2.622 N/A GLN 237.A NE2 SER 87.A OG no hydrogen 3.134 N/A ARG 240.A NE GLY 235.A O no hydrogen 2.952 N/A ILE 241.A N GLY 230.A O no hydrogen 2.965 N/A TYR 242.A N GLY 264.A O no hydrogen 2.661 N/A SER 243.A N VAL 227.A O no hydrogen 2.817 N/A SER 243.A OG GLU 218.A OE1 no hydrogen 2.938 N/A ARG 245.A N SER 243.A OG no hydrogen 2.884 N/A ARG 245.A NE ILE 219.A O no hydrogen 2.656 N/A ARG 245.A NH2 ILE 219.A O no hydrogen 3.317 N/A GLY 246.A N SER 243.A O no hydrogen 2.863 N/A ILE 247.A N LYS 225.A O no hydrogen 2.791 N/A ALA 248.A N PRO 160.A O no hydrogen 3.167 N/A ILE 249.A N TYR 265.A OH no hydrogen 2.875 N/A THR 250.A OG1 LYS 162.A O no hydrogen 3.227 N/A LEU 251.A N GLN 161.A OE1 no hydrogen 3.310 N/A SER 252.A N LYS 261.A O no hydrogen 3.044 N/A PHE 259.A N GLY 238.A O no hydrogen 2.701 N/A LYS 261.A NZ SER 296.A O no hydrogen 3.231 N/A THR 262.A N PHE 259.A O no hydrogen 3.222 N/A THR 262.A OG1 GLY 263.A O no hydrogen 3.114 N/A GLY 263.A N PHE 259.A O no hydrogen 2.900 N/A GLY 264.A N ARG 240.A O no hydrogen 3.028 N/A TYR 265.A N ARG 272.A O no hydrogen 2.740 N/A LEU 266.A N TYR 242.A O no hydrogen 3.171 N/A VAL 267.A N LYS 270.A O no hydrogen 2.804 N/A LYS 270.A N VAL 267.A O no hydrogen 3.049 N/A ARG 272.A N TYR 265.A O no hydrogen 2.855 N/A ARG 272.A NH1 LYS 273.A O no hydrogen 2.789 N/A ARG 272.A NH1 GLU 278.A OE1 no hydrogen 2.943 N/A ARG 272.A NH2 GLU 278.A OE1 no hydrogen 3.271 N/A ARG 272.A NH2 GLU 278.A OE2 no hydrogen 3.031 N/A LEU 274.A N THR 262.A OG1 no hydrogen 3.004 N/A HIS 275.A N GLU 278.A OE1 no hydrogen 2.974 N/A ARG 277.A NH1 TYR 289.A O no hydrogen 3.014 N/A ARG 277.A NH2 TYR 289.A O no hydrogen 2.591 N/A CYS 279.A N HIS 275.A O no hydrogen 2.843 N/A CYS 279.A SG HIS 275.A O no hydrogen 3.494 N/A ALA 280.A N PRO 276.A O no hydrogen 2.888 N/A ARG 281.A N ARG 277.A O no hydrogen 2.967 N/A ARG 281.A NE ASP 287.A OD1 no hydrogen 2.917 N/A ARG 281.A NH1 LEU 195.A O no hydrogen 2.708 N/A VAL 282.A N GLU 278.A O no hydrogen 2.723 N/A MET 283.A N CYS 279.A O no hydrogen 2.631 N/A MET 283.A N ALA 280.A O no hydrogen 2.928 N/A GLY 284.A N ARG 281.A O no hydrogen 3.018 N/A TYR 285.A N ALA 280.A O no hydrogen 2.742 N/A TYR 285.A OH SER 305.A OG no hydrogen 2.761 N/A TYR 289.A N PRO 286.A O no hydrogen 2.691 N/A TYR 289.A OH LEU 21.A O no hydrogen 2.740 N/A LYS 290.A N ASN 52.A OD1 no hydrogen 2.847 N/A HIS 292.A NE2 GLU 47.A OE1 no hydrogen 2.901 N/A SER 294.A N HIS 292.A ND1 no hydrogen 3.088 N/A GLN 297.A N SER 294.A OG no hydrogen 3.216 N/A ALA 298.A N SER 294.A O no hydrogen 2.631 N/A TYR 299.A N THR 295.A O no hydrogen 2.768 N/A TYR 299.A OH LEU 274.A O no hydrogen 2.389 N/A LYS 300.A N SER 296.A O no hydrogen 3.028 N/A GLN 301.A N GLN 297.A O no hydrogen 2.774 N/A PHE 302.A N ALA 298.A O no hydrogen 3.017 N/A GLY 303.A N TYR 299.A O no hydrogen 2.713 N/A ASN 304.A N LYS 300.A O no hydrogen 3.078 N/A SER 305.A N PHE 302.A O no hydrogen 3.191 N/A SER 305.A OG TYR 285.A OH no hydrogen 2.761 N/A VAL 306.A N SER 305.A OG no hydrogen 2.484 N/A ILE 308.A N MET 283.A O no hydrogen 3.134 N/A LEU 311.A N VAL 307.A O no hydrogen 3.160 N/A GLN 312.A N ILE 308.A O no hydrogen 2.709 N/A GLN 312.A N ASN 309.A O no hydrogen 2.979 N/A GLN 312.A NE2 ILE 2.A O no hydrogen 2.676 N/A GLN 312.A NE2 SER 30.A OG no hydrogen 2.926 N/A TYR 313.A N ASN 309.A O no hydrogen 3.016 N/A ILE 314.A N VAL 310.A O no hydrogen 3.136 N/A ALA 315.A N LEU 311.A O no hydrogen 2.946 N/A TYR 316.A N GLN 312.A O no hydrogen 2.723 N/A TYR 316.A OH ASP 6.A OD2 no hydrogen 2.471 N/A ASN 317.A N TYR 313.A O no hydrogen 3.272 N/A ASN 317.A ND2 GLN 181.A O no hydrogen 3.219 N/A ILE 318.A N ILE 314.A O no hydrogen 2.836 N/A GLY 319.A N ALA 315.A O no hydrogen 3.001 N/A SER 320.A N TYR 316.A O no hydrogen 3.033 N/A SER 320.A OG TYR 316.A O no hydrogen 3.038 N/A SER 321.A N ASN 317.A O no hydrogen 3.234 N/A SER 321.A OG ASN 179.A OD1 no hydrogen 3.234 N/A SER 321.A OG ASN 317.A O no hydrogen 3.288 N/A LEU 322.A N ILE 318.A O no hydrogen 2.989 N/A ASN 323.A N GLY 319.A O no hydrogen 2.655 N/A ASN 323.A ND2 GLN 8.A O no hydrogen 2.843 N/A ASN 323.A ND2 GLN 8.A OE1 no hydrogen 3.664 N/A PHE 324.A N SER 320.A O no hydrogen 2.891 N/A PHE 324.A N SER 321.A O no hydrogen 3.348 N/A