Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2iew_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 4.A N LEU 45.A O no hydrogen 2.746 N/A LYS 6.A N LEU 43.A O no hydrogen 3.005 N/A LYS 6.A NZ GLU 12.A OE1 no hydrogen 2.622 N/A LYS 6.A NZ GLU 12.A OE2 no hydrogen 3.531 N/A ALA 8.A N GLN 41.A O no hydrogen 2.792 N/A GLN 11.A NE2 SER 227.A O no hydrogen 2.925 N/A LEU 13.A N PHE 9.A O no hydrogen 2.988 N/A GLU 14.A N PRO 10.A O no hydrogen 2.834 N/A PHE 15.A N GLN 11.A O no hydrogen 3.016 N/A TYR 16.A N GLU 12.A O no hydrogen 3.043 N/A LYS 17.A N LEU 13.A O no hydrogen 3.010 N/A LYS 17.A NZ GLU 14.A OE2 no hydrogen 3.229 N/A ALA 18.A N GLU 14.A O no hydrogen 2.817 N/A ILE 19.A N PHE 15.A O no hydrogen 3.012 N/A GLN 20.A N TYR 16.A O no hydrogen 2.858 N/A LEU 25.A N GLU 178.A OE2 no hydrogen 3.213 N/A SER 27.A N PRO 24.A O no hydrogen 3.051 N/A SER 27.A OG PRO 24.A O no hydrogen 2.878 N/A TRP 28.A N LEU 25.A O no hydrogen 2.941 N/A TRP 28.A NE1 THR 174.A OG1 no hydrogen 3.006 N/A MET 29.A N CYS 26.A O no hydrogen 3.218 N/A THR 31.A N GLU 46.A OE1 no hydrogen 3.058 N/A THR 31.A OG1 GLU 46.A OE1 no hydrogen 3.068 N/A LEU 33.A N VAL 44.A O no hydrogen 2.886 N/A LEU 36.A N TYR 42.A O no hydrogen 2.938 N/A GLU 38.A N LYS 40.A O no hydrogen 2.805 N/A SER 39.A OG GLU 38.A O no hydrogen 3.127 N/A TYR 42.A N LEU 36.A O no hydrogen 2.844 N/A LEU 43.A N LYS 6.A O no hydrogen 2.628 N/A VAL 44.A N GLY 34.A O no hydrogen 2.854 N/A LEU 45.A N ILE 4.A O no hydrogen 2.946 N/A GLU 46.A N THR 31.A O no hydrogen 2.952 N/A ASN 47.A N LEU 2.A O no hydrogen 2.860 N/A ASN 47.A ND2 GLY 1.A O no hydrogen 2.808 N/A LEU 49.A N ASN 47.A OD1 no hydrogen 3.001 N/A TYR 50.A N ASN 47.A O no hydrogen 3.118 N/A PHE 52.A N LEU 49.A O no hydrogen 3.148 N/A SER 53.A N GLU 192.A OE1 no hydrogen 2.705 N/A SER 53.A OG ASP 194.A OD2 no hydrogen 2.580 N/A LYS 54.A N GLU 192.A OE2 no hydrogen 2.796 N/A LYS 54.A NZ ASP 122.A OD1 no hydrogen 2.874 N/A LYS 54.A NZ ASP 122.A OD2 no hydrogen 3.499 N/A ASN 56.A N TYR 191.A O no hydrogen 2.822 N/A ASN 56.A ND2 LYS 54.A O no hydrogen 3.018 N/A ASN 56.A ND2 GLN 101.A OE1 no hydrogen 3.042 N/A ILE 57.A N LYS 99.A O no hydrogen 2.830 N/A LEU 58.A N PHE 189.A O no hydrogen 2.892 N/A ASP 59.A N GLY 97.A O no hydrogen 3.023 N/A ILE 60.A N LEU 187.A O no hydrogen 2.902 N/A LYS 61.A N ARG 94.A O no hydrogen 2.778 N/A LYS 61.A NZ SER 184.A O no hydrogen 2.947 N/A LYS 61.A NZ SER 186.A OG no hydrogen 2.710 N/A LYS 61.A NZ ASP 223.A OD2 no hydrogen 2.880 N/A LEU 62.A N SER 185.A O no hydrogen 2.912 N/A GLY 63.A N GLY 92.A O no hydrogen 2.692 N/A LYS 64.A NZ GLU 241.A OE1 no hydrogen 3.162 N/A THR 65.A N ASN 238.A OD1 no hydrogen 3.093 N/A ARG 76.A N SER 72.A O no hydrogen 2.740 N/A GLU 77.A N LEU 73.A O no hydrogen 2.930 N/A ARG 78.A N GLU 74.A O no hydrogen 3.177 N/A MET 79.A N LYS 75.A O no hydrogen 2.723 N/A LYS 80.A N ARG 76.A O no hydrogen 3.007 N/A ARG 81.A N GLU 77.A O no hydrogen 3.225 N/A VAL 82.A N ARG 78.A O no hydrogen 3.050 N/A SER 83.A N MET 79.A O no hydrogen 3.046 N/A SER 83.A OG LYS 64.A O no hydrogen 2.568 N/A GLU 84.A N LYS 80.A O no hydrogen 2.835 N/A THR 85.A N ARG 81.A O no hydrogen 3.033 N/A THR 85.A N VAL 82.A O no hydrogen 3.377 N/A THR 85.A OG1 ARG 81.A O no hydrogen 2.743 N/A THR 86.A OG1 VAL 82.A O no hydrogen 2.861 N/A THR 87.A OG1 PHE 93.A O no hydrogen 2.618 N/A SER 88.A N THR 86.A OG1 no hydrogen 3.234 N/A GLY 89.A N SER 83.A O no hydrogen 2.960 N/A SER 90.A OG THR 87.A O no hydrogen 3.413 N/A SER 90.A OG ASP 136.A OD1 no hydrogen 2.619 N/A SER 90.A OG ASP 136.A OD2 no hydrogen 3.389 N/A LEU 91.A N THR 87.A O no hydrogen 2.727 N/A GLY 92.A N SER 88.A O no hydrogen 2.837 N/A ARG 94.A N LYS 61.A O no hydrogen 2.944 N/A ARG 94.A NH1 SER 88.A OG no hydrogen 3.043 N/A CYS 96.A N ASP 59.A O no hydrogen 2.813 N/A GLY 97.A N ASP 59.A O no hydrogen 3.469 N/A MET 98.A N ILE 126.A O no hydrogen 3.046 N/A LYS 99.A N ILE 57.A O no hydrogen 2.895 N/A ILE 100.A N ILE 124.A O no hydrogen 3.127 N/A GLN 101.A N ASN 56.A OD1 no hydrogen 2.884 N/A GLN 101.A NE2 ASP 122.A OD2 no hydrogen 3.050 N/A LYS 102.A N ASP 122.A O no hydrogen 2.690 N/A ASN 103.A ND2 ASN 148.A O no hydrogen 2.899 N/A SER 105.A N ASN 103.A OD1 no hydrogen 3.020 N/A SER 105.A OG ASN 103.A OD1 no hydrogen 3.231 N/A LEU 107.A N ASN 103.A O no hydrogen 2.975 N/A ASN 108.A N PRO 104.A O no hydrogen 3.243 N/A GLN 109.A N VAL 106.A O no hydrogen 2.798 N/A LEU 110.A N VAL 106.A O no hydrogen 3.186 N/A TYR 114.A N SER 111.A O no hydrogen 3.063 N/A GLU 116.A N PHE 125.A O no hydrogen 2.964 N/A ASP 122.A N ASP 122.A OD1 no hydrogen 2.582 N/A TYR 123.A N SER 121.A OG no hydrogen 3.146 N/A TYR 123.A OH PRO 55.A O no hydrogen 2.628 N/A ILE 124.A N ILE 100.A O no hydrogen 2.829 N/A PHE 125.A N GLU 116.A O no hydrogen 2.909 N/A ILE 126.A N MET 98.A O no hydrogen 2.802 N/A ASN 127.A N TYR 114.A O no hydrogen 3.036 N/A ASN 127.A ND2 GLU 113.A O no hydrogen 2.925 N/A TYR 130.A N ASN 127.A OD1 no hydrogen 3.087 N/A GLY 131.A N ASN 127.A O no hydrogen 3.387 N/A ARG 132.A N LYS 128.A O no hydrogen 2.824 N/A SER 133.A N LEU 129.A O no hydrogen 3.034 N/A SER 133.A N TYR 130.A O no hydrogen 3.241 N/A SER 133.A OG LEU 129.A O no hydrogen 2.671 N/A SER 133.A OG TYR 130.A O no hydrogen 2.986 N/A ARG 134.A NE TYR 130.A O no hydrogen 2.953 N/A ARG 134.A NH2 SER 133.A OG no hydrogen 3.041 N/A THR 135.A N ASN 138.A OD1 no hydrogen 2.879 N/A GLN 137.A N THR 135.A OG1 no hydrogen 3.184 N/A ASN 138.A N THR 135.A O no hydrogen 3.320 N/A ASN 138.A N THR 135.A OG1 no hydrogen 3.091 N/A ALA 142.A N ASN 138.A O no hydrogen 3.059 N/A ILE 143.A N VAL 139.A O no hydrogen 3.039 N/A GLU 144.A N SER 140.A O no hydrogen 3.005 N/A LEU 145.A N ASP 141.A O no hydrogen 2.899 N/A TYR 146.A N ALA 142.A O no hydrogen 3.277 N/A TYR 146.A OH ASN 56.A O no hydrogen 2.635 N/A PHE 147.A N ILE 143.A O no hydrogen 3.436 N/A ASN 148.A N LEU 145.A O no hydrogen 3.026 N/A ASN 149.A N PHE 147.A O no hydrogen 2.699 N/A ASN 149.A ND2 ASN 56.A OD1 no hydrogen 3.216 N/A ASN 149.A ND2 GLN 101.A OE1 no hydrogen 3.058 N/A HIS 151.A N ASN 149.A OD1 no hydrogen 2.815 N/A LEU 152.A N ASN 149.A O no hydrogen 3.359 N/A ARG 156.A N SER 153.A OG no hydrogen 3.119 N/A ARG 156.A NE ASP 203.A OD1 no hydrogen 3.421 N/A ARG 156.A NE ASP 203.A OD2 no hydrogen 3.177 N/A ARG 156.A NH2 GLU 199.A OE2 no hydrogen 3.060 N/A ARG 156.A NH2 ASP 203.A OD1 no hydrogen 2.886 N/A LYS 157.A N SER 153.A O no hydrogen 2.994 N/A LYS 157.A NZ LEU 152.A O no hydrogen 3.226 N/A HIS 158.A N ASP 154.A O no hydrogen 3.053 N/A GLN 159.A N ALA 155.A O no hydrogen 2.932 N/A GLN 159.A NE2 ASP 203.A O no hydrogen 2.910 N/A LEU 160.A N ARG 156.A O no hydrogen 3.001 N/A LYS 161.A N LYS 157.A O no hydrogen 3.180 N/A LYS 162.A N HIS 158.A O no hydrogen 2.963 N/A THR 163.A N GLN 159.A O no hydrogen 2.838 N/A THR 163.A OG1 GLN 159.A O no hydrogen 3.021 N/A PHE 164.A N LEU 160.A O no hydrogen 2.784 N/A LEU 165.A N LYS 161.A O no hydrogen 2.942 N/A LYS 166.A N LYS 162.A O no hydrogen 3.102 N/A ARG 167.A N THR 163.A O no hydrogen 3.003 N/A ARG 167.A NE LEU 207.A O no hydrogen 2.738 N/A ARG 167.A NH1 SER 217.A OG no hydrogen 2.797 N/A ARG 167.A NH2 ASP 205.A OD1 no hydrogen 3.501 N/A ARG 167.A NH2 LYS 206.A O no hydrogen 2.823 N/A ARG 167.A NH2 SER 217.A OG no hydrogen 3.283 N/A LEU 168.A N PHE 164.A O no hydrogen 2.932 N/A GLN 169.A N LEU 165.A O no hydrogen 2.914 N/A LEU 170.A N LYS 166.A O no hydrogen 3.029 N/A PHE 171.A N ARG 167.A O no hydrogen 2.785 N/A TYR 172.A N LEU 168.A O no hydrogen 2.958 N/A ASN 173.A N GLN 169.A O no hydrogen 3.088 N/A THR 174.A N LEU 170.A O no hydrogen 2.987 N/A THR 174.A OG1 ALA 23.A O no hydrogen 2.614 N/A THR 174.A OG1 LEU 170.A O no hydrogen 3.183 N/A MET 175.A N PHE 171.A O no hydrogen 2.952 N/A LEU 176.A N TYR 172.A O no hydrogen 3.084 N/A GLU 177.A N THR 174.A O no hydrogen 2.920 N/A ARG 181.A N GLU 228.A O no hydrogen 3.014 N/A ARG 181.A NH1 VAL 180.A O no hydrogen 2.798 N/A ARG 181.A NH1 GLY 234.A O no hydrogen 2.869 N/A ARG 181.A NH2 LYS 233.A O no hydrogen 2.939 N/A MET 182.A N ASP 236.A OD2 no hydrogen 2.728 N/A ILE 183.A N HIS 226.A O no hydrogen 3.010 N/A SER 186.A N ILE 222.A O no hydrogen 3.076 N/A SER 186.A OG ASP 59.A OD1 no hydrogen 2.586 N/A SER 186.A OG ASP 59.A OD2 no hydrogen 3.445 N/A LEU 187.A N ILE 60.A O no hydrogen 2.741 N/A LEU 188.A N SER 220.A O no hydrogen 2.782 N/A PHE 189.A N LEU 58.A O no hydrogen 2.789 N/A ILE 190.A N SER 218.A O no hydrogen 2.912 N/A TYR 191.A N ASN 56.A O no hydrogen 3.015 N/A TYR 191.A OH TYR 146.A O no hydrogen 2.630 N/A GLU 192.A N LEU 216.A O no hydrogen 2.711 N/A GLY 193.A N LYS 54.A O no hydrogen 2.822 N/A ASP 194.A N GLU 192.A OE2 no hydrogen 2.936 N/A GLU 196.A N ASP 194.A OD1 no hydrogen 2.993 N/A ARG 197.A N ASP 194.A O no hydrogen 2.979 N/A ARG 197.A NH1 GLU 192.A OE1 no hydrogen 2.877 N/A ARG 197.A NH1 SER 215.A O no hydrogen 2.897 N/A ARG 197.A NH2 SER 215.A O no hydrogen 2.898 N/A TRP 198.A N ASP 194.A O no hydrogen 3.364 N/A TRP 198.A NE1 GLU 192.A O no hydrogen 2.773 N/A GLU 199.A N PRO 195.A O no hydrogen 2.950 N/A LEU 200.A N GLU 196.A O no hydrogen 2.867 N/A LEU 201.A N ARG 197.A O no hydrogen 3.007 N/A ASN 202.A N GLU 199.A O no hydrogen 3.060 N/A ASP 203.A N TRP 198.A O no hydrogen 2.889 N/A VAL 204.A N LEU 201.A O no hydrogen 3.013 N/A LYS 206.A NZ SER 215.A OG no hydrogen 2.879 N/A ASP 214.A N ASP 211.A OD1 no hydrogen 2.744 N/A LEU 216.A N ASP 205.A OD1 no hydrogen 3.085 N/A SER 217.A N ASP 205.A OD1 no hydrogen 3.138 N/A SER 217.A OG ASP 205.A OD2 no hydrogen 2.626 N/A SER 218.A N ILE 190.A O no hydrogen 2.807 N/A SER 220.A N LEU 188.A O no hydrogen 2.834 N/A LEU 221.A N TRP 28.A O no hydrogen 2.891 N/A ILE 222.A N SER 186.A O no hydrogen 2.923 N/A PHE 224.A N GLU 12.A OE2 no hydrogen 2.947 N/A SER 227.A N PHE 224.A O no hydrogen 3.129 N/A GLU 228.A N ARG 181.A O no hydrogen 3.083 N/A THR 230.A N GLU 179.A O no hydrogen 2.872 N/A GLY 232.A N GLU 179.A OE1 no hydrogen 2.783 N/A LYS 233.A N THR 230.A O no hydrogen 3.158 N/A GLY 234.A N GLU 179.A OE2 no hydrogen 2.770 N/A ASN 238.A ND2 THR 65.A O no hydrogen 3.188 N/A VAL 239.A N ASP 236.A O no hydrogen 3.267 N/A VAL 239.A N ASP 236.A OD1 no hydrogen 3.363 N/A ILE 240.A N ASP 236.A O no hydrogen 3.129 N/A GLU 241.A N GLU 237.A O no hydrogen 3.134 N/A VAL 243.A N VAL 239.A O no hydrogen 3.265 N/A GLU 244.A N ILE 240.A O no hydrogen 2.734 N/A THR 245.A N GLU 241.A O no hydrogen 3.222 N/A THR 245.A OG1 LEU 91.A O no hydrogen 2.677 N/A THR 245.A OG1 GLU 241.A O no hydrogen 3.218 N/A LEU 246.A N GLY 242.A O no hydrogen 3.008 N/A LEU 247.A N VAL 243.A O no hydrogen 2.856 N/A ASP 248.A N GLU 244.A O no hydrogen 3.234 N/A ILE 249.A N THR 245.A O no hydrogen 2.987 N/A PHE 250.A N LEU 246.A O no hydrogen 2.865 N/A MET 251.A N LEU 247.A O no hydrogen 2.844 N/A LYS 252.A N ASP 248.A O no hydrogen 3.021 N/A PHE 253.A N ILE 249.A O no hydrogen 3.090 N/A LEU 254.A N MET 251.A O no hydrogen 3.032 N/A GLU 255.A N LYS 252.A O no hydrogen 3.031 N/A HIS 257.A ND1 GLU 255.A O no hydrogen 3.272 N/A