Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2ik9_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 1.A N ASP 22.A OD1 no hydrogen 2.999 N/A THR 3.A N GLU 20.A O no hydrogen 3.012 N/A THR 3.A OG1 GLU 20.A OE1 no hydrogen 2.809 N/A ARG 5.A N TYR 18.A O no hydrogen 2.816 N/A ARG 5.A NE GLU 20.A OE2 no hydrogen 2.803 N/A ARG 5.A NH1 PRO 258.A O no hydrogen 2.981 N/A ARG 5.A NH2 GLU 20.A OE2 no hydrogen 3.014 N/A ARG 5.A NH2 GLY 23.A O no hydrogen 3.417 N/A GLN 6.A NE2 GLY 8.A O no hydrogen 2.934 N/A ILE 7.A N LYS 16.A O no hydrogen 2.807 N/A GLY 8.A N SER 261.A O no hydrogen 3.095 N/A GLY 8.A N SER 261.A OG no hydrogen 3.166 N/A ASN 11.A ND2 ALA 266.A O no hydrogen 2.981 N/A THR 12.A OG1 ALA 9.A O no hydrogen 2.648 N/A THR 12.A OG1 GLU 14.A OE1 no hydrogen 3.329 N/A TYR 15.A N THR 12.A O no hydrogen 3.378 N/A LYS 16.A N ILE 7.A O no hydrogen 2.983 N/A LYS 16.A NZ GLU 63.A OE1 no hydrogen 2.837 N/A VAL 17.A N ILE 68.A O no hydrogen 2.837 N/A TYR 18.A N ARG 5.A O no hydrogen 2.908 N/A GLU 20.A N THR 3.A O no hydrogen 2.881 N/A LYS 21.A N LYS 24.A O no hydrogen 2.775 N/A ASP 22.A N THR 1.A O no hydrogen 2.922 N/A LYS 24.A N LYS 21.A O no hydrogen 2.964 N/A VAL 26.A N ILE 19.A O no hydrogen 2.986 N/A SER 27.A N ASP 31.A OD2 no hydrogen 2.850 N/A SER 27.A OG HIS 30.A ND1 no hydrogen 3.338 N/A SER 27.A OG ASN 66.A OD1 no hydrogen 2.614 N/A ALA 28.A N LEU 65.A O no hydrogen 3.183 N/A PHE 29.A N SER 27.A OG no hydrogen 3.150 N/A HIS 30.A N SER 27.A OG no hydrogen 2.938 N/A ASP 31.A N SER 27.A O no hydrogen 2.988 N/A LEU 34.A N GLN 98.A OE1 no hydrogen 3.040 N/A ALA 36.A N ILE 42.A O no hydrogen 2.759 N/A ASP 37.A N ILE 42.A O no hydrogen 3.012 N/A ASN 40.A N ASP 37.A O no hydrogen 3.216 N/A ASN 40.A N ASP 37.A OD1 no hydrogen 3.289 N/A ASN 40.A ND2 ASP 37.A OD2 no hydrogen 2.881 N/A ASN 41.A N LYS 38.A O no hydrogen 3.106 N/A ILE 42.A N ASP 37.A O no hydrogen 3.006 N/A PHE 43.A N VAL 133.A O no hydrogen 2.919 N/A ASN 44.A N LEU 34.A O no hydrogen 2.901 N/A ASN 44.A ND2 PRO 33.A O no hydrogen 2.881 N/A MET 45.A N LYS 131.A O no hydrogen 2.758 N/A VAL 46.A N ALA 95.A O no hydrogen 2.939 N/A VAL 47.A N GLN 129.A O no hydrogen 2.894 N/A GLU 48.A N TYR 93.A O no hydrogen 2.906 N/A ILE 49.A N TYR 93.A O no hydrogen 2.886 N/A ARG 51.A N ASN 92.A OD1 no hydrogen 3.056 N/A ARG 51.A NH1 GLU 122.A O no hydrogen 3.491 N/A ARG 51.A NH2 GLU 122.A O no hydrogen 2.802 N/A TRP 52.A N TYR 89.A O no hydrogen 2.729 N/A THR 53.A N PRO 50.A O no hydrogen 3.280 N/A THR 53.A OG1 PRO 50.A O no hydrogen 2.696 N/A ASN 54.A ND2 VAL 80.A O no hydrogen 2.853 N/A ASN 54.A ND2 ASN 82.A OD1 no hydrogen 2.873 N/A LYS 56.A N ARG 78.A O no hydrogen 3.008 N/A LYS 56.A NZ TYR 89.A OH no hydrogen 3.337 N/A LEU 57.A N ALA 55.A O no hydrogen 3.032 N/A GLU 58.A N ILE 69.A O no hydrogen 2.961 N/A ILE 59.A N GLU 48.A OE2 no hydrogen 2.869 N/A THR 60.A N PRO 67.A O no hydrogen 2.864 N/A THR 60.A OG1 GLU 58.A O no hydrogen 3.414 N/A THR 60.A OG1 PRO 67.A O no hydrogen 2.768 N/A LYS 61.A NZ ASP 113.A OD1.A no hydrogen 2.856 N/A LYS 61.A NZ ASP 113.A OD1.B no hydrogen 2.963 N/A THR 64.A OG1 ASP 237.A OD2 no hydrogen 2.788 N/A ASN 66.A N GLU 63.A O no hydrogen 2.827 N/A ASN 66.A ND2 THR 60.A O no hydrogen 2.976 N/A ASN 66.A ND2 ASP 237.A O no hydrogen 3.398 N/A ILE 68.A N VAL 17.A O no hydrogen 2.809 N/A ILE 69.A N GLU 58.A O no hydrogen 2.968 N/A GLN 70.A NE2 ARG 78.A O no hydrogen 2.848 N/A ASP 71.A N LYS 56.A O no hydrogen 2.787 N/A LYS 73.A N LYS 76.A O no hydrogen 2.823 N/A LYS 76.A N LYS 73.A O no hydrogen 2.996 N/A ARG 78.A N ASP 71.A O no hydrogen 2.911 N/A ARG 78.A NE THR 72.A O no hydrogen 3.102 N/A ARG 78.A NH2 THR 72.A O no hydrogen 3.377 N/A VAL 80.A N ASN 54.A O no hydrogen 2.848 N/A ARG 81.A NH2 SER 271.A O no hydrogen 2.807 N/A ASN 82.A ND2 ASP 273.A O no hydrogen 3.165 N/A ASN 82.A ND2 LYS 274.A O no hydrogen 3.558 N/A CYS 83.A SG ARG 81.A O no hydrogen 3.781 N/A PHE 84.A N PHE 276.A O no hydrogen 2.801 N/A HIS 86.A N CYS 83.A O no hydrogen 2.749 N/A GLY 88.A N ASN 82.A OD1 no hydrogen 2.822 N/A TYR 89.A N THR 53.A O no hydrogen 3.022 N/A ASN 92.A N GLU 119.A O no hydrogen 3.124 N/A ASN 92.A ND2 GLU 119.A OE1 no hydrogen 2.951 N/A ASN 92.A ND2 THR 123.A O no hydrogen 2.873 N/A TYR 93.A N ILE 49.A O no hydrogen 2.872 N/A GLY 94.A N VAL 117.A O no hydrogen 2.955 N/A ALA 95.A N VAL 46.A O no hydrogen 2.982 N/A PHE 96.A N ILE 115.A O no hydrogen 3.080 N/A GLN 98.A N PHE 29.A O no hydrogen 2.839 N/A GLN 98.A NE2 HIS 30.A O no hydrogen 2.920 N/A THR 99.A OG1 PHE 96.A O no hydrogen 2.733 N/A TRP 100.A N THR 218.A O no hydrogen 3.036 N/A TRP 100.A NE1 ASN 112.A OD1 no hydrogen 3.012 N/A GLU 101.A N ASP 113.A O.A no hydrogen 2.891 N/A GLU 101.A N ASP 113.A O.B no hydrogen 2.811 N/A ASN 104.A N ASP 102.A OD1 no hydrogen 2.924 N/A ASN 104.A ND2 SER 231.A OG no hydrogen 3.113 N/A THR 106.A OG1 THR 147.A OG1 no hydrogen 2.771 N/A ASP 111.A N GLU 101.A OE1 no hydrogen 3.113 N/A ASN 112.A N GLU 101.A O no hydrogen 2.859 N/A ASP 113.A N.A ASP 111.A OD1 no hydrogen 3.079 N/A ASP 113.A N.B ASP 111.A OD1 no hydrogen 3.079 N/A ILE 115.A N THR 99.A OG1 no hydrogen 2.849 N/A ASP 116.A N TRP 149.A O no hydrogen 3.315 N/A VAL 117.A N GLY 94.A O no hydrogen 2.887 N/A LEU 118.A N VAL 151.A O no hydrogen 2.725 N/A GLU 119.A N ASN 92.A O no hydrogen 2.816 N/A ILE 120.A N ALA 153.A O no hydrogen 2.990 N/A GLY 121.A N GLU 119.A OE2 no hydrogen 2.891 N/A GLU 122.A N ASP 158.A OD1 no hydrogen 2.885 N/A ALA 125.A N ASN 92.A OD1 no hydrogen 2.943 N/A TYR 126.A N GLN 129.A OE1 no hydrogen 3.112 N/A THR 127.A OG1 GLU 48.A O no hydrogen 2.829 N/A GLY 128.A N VAL 47.A O no hydrogen 2.762 N/A GLN 129.A N TYR 126.A O no hydrogen 3.018 N/A LYS 131.A N MET 45.A O no hydrogen 3.029 N/A LYS 131.A NZ GLU 119.A OE1 no hydrogen 3.159 N/A LYS 131.A NZ ASP 155.A OD2 no hydrogen 2.786 N/A GLN 132.A NE2 ASN 44.A OD1 no hydrogen 2.928 N/A GLN 132.A NE2 VAL 130.A O no hydrogen 3.678 N/A VAL 133.A N PHE 43.A O no hydrogen 2.873 N/A LYS 134.A N ILE 154.A O no hydrogen 2.941 N/A LYS 134.A NZ ALA 161.A O no hydrogen 2.893 N/A LYS 134.A NZ LEU 164.A O no hydrogen 2.713 N/A LEU 136.A N ILE 152.A O no hydrogen 2.792 N/A GLY 137.A N ILE 152.A O no hydrogen 3.393 N/A ILE 138.A N LYS 206.A O no hydrogen 2.935 N/A MET 139.A N LYS 150.A O no hydrogen 2.896 N/A LEU 141.A N GLU 148.A O no hydrogen 3.006 N/A LEU 142.A N GLN 198.A O no hydrogen 2.687 N/A ASP 143.A N GLU 146.A O no hydrogen 2.977 N/A GLU 146.A N ASP 143.A O no hydrogen 3.052 N/A THR 147.A N VAL 109.A O no hydrogen 2.860 N/A THR 147.A OG1 THR 106.A OG1 no hydrogen 2.771 N/A THR 147.A OG1 ALA 108.A O no hydrogen 3.029 N/A GLU 148.A N LEU 141.A O no hydrogen 2.728 N/A TRP 149.A N GLU 101.A OE2 no hydrogen 3.087 N/A LYS 150.A N MET 139.A O no hydrogen 2.831 N/A LYS 150.A NZ TYR 93.A OH no hydrogen 3.154 N/A LYS 150.A NZ ASP 116.A OD2 no hydrogen 2.794 N/A LYS 150.A NZ GLU 148.A OE1 no hydrogen 2.828 N/A VAL 151.A N ASP 116.A O no hydrogen 2.868 N/A ILE 152.A N GLY 137.A O no hydrogen 2.874 N/A ALA 153.A N LEU 118.A O no hydrogen 2.863 N/A ILE 154.A N LYS 134.A O no hydrogen 3.019 N/A ASP 155.A N GLU 119.A OE2 no hydrogen 2.867 N/A ILE 156.A N GLN 132.A O no hydrogen 2.960 N/A ASN 157.A N ASP 155.A OD1 no hydrogen 2.885 N/A ASP 158.A N ASP 155.A O no hydrogen 3.004 N/A LEU 160.A N ASP 158.A OD2 no hydrogen 2.857 N/A ALA 161.A N ASP 158.A O no hydrogen 2.952 N/A LYS 163.A N LEU 160.A O no hydrogen 2.858 N/A LEU 164.A N ALA 161.A O no hydrogen 3.029 N/A ASN 165.A N ASP 169.A OD2 no hydrogen 2.841 N/A ASP 166.A N ASP 169.A OD2 no hydrogen 3.171 N/A ILE 167.A N ASP 166.A OD1 no hydrogen 2.792 N/A ASP 169.A N ASP 166.A O no hydrogen 2.912 N/A VAL 170.A N ILE 167.A O no hydrogen 3.026 N/A LYS 172.A N GLU 168.A O no hydrogen 3.234 N/A TYR 173.A N ASP 169.A O no hydrogen 3.016 N/A PHE 174.A N VAL 170.A O no hydrogen 2.824 N/A LEU 177.A N PHE 174.A O no hydrogen 2.950 N/A ALA 180.A N GLY 176.A O no hydrogen 2.894 N/A THR 181.A N LEU 177.A O no hydrogen 2.870 N/A THR 181.A OG1 LEU 177.A O no hydrogen 2.742 N/A ASN 182.A N LEU 178.A O no hydrogen 2.968 N/A GLU 183.A N ARG 179.A O no hydrogen 2.951 N/A TRP 184.A N ALA 180.A O no hydrogen 2.758 N/A TRP 184.A NE1 GLY 88.A O no hydrogen 2.937 N/A PHE 185.A N THR 181.A O no hydrogen 3.168 N/A ARG 186.A N ASN 182.A O no hydrogen 3.151 N/A ARG 186.A NE GLU 196.A OE2 no hydrogen 3.018 N/A ARG 186.A NH2 GLU 196.A OE2 no hydrogen 2.977 N/A ILE 187.A N GLU 183.A O no hydrogen 3.026 N/A ILE 187.A N TRP 184.A O no hydrogen 3.208 N/A LYS 189.A NZ ASP 143.A OD1 no hydrogen 2.718 N/A ILE 190.A N ILE 187.A O no hydrogen 2.936 N/A ASP 192.A N LYS 189.A O no hydrogen 2.959 N/A GLY 193.A N ILE 190.A O no hydrogen 2.837 N/A LYS 194.A N LYS 189.A O no hydrogen 3.208 N/A ASN 197.A N ARG 186.A O no hydrogen 2.904 N/A ASN 197.A ND2 PHE 185.A O no hydrogen 3.007 N/A GLN 198.A N LEU 142.A O no hydrogen 3.220 N/A ALA 200.A N ALA 140.A O no hydrogen 2.889 N/A GLY 203.A N ALA 200.A O no hydrogen 3.064 N/A GLU 204.A N PHE 201.A O no hydrogen 2.937 N/A LYS 206.A N ILE 138.A O no hydrogen 2.777 N/A LYS 206.A NZ GLU 204.A OE1 no hydrogen 3.082 N/A LYS 208.A N ASP 166.A OD1 no hydrogen 2.870 N/A LYS 208.A NZ ASN 165.A OD1 no hydrogen 2.844 N/A LYS 209.A NZ ASP 213.A OD2 no hydrogen 2.977 N/A TYR 210.A OH GLU 105.A OE1 no hydrogen 2.630 N/A ALA 211.A N ASN 207.A O no hydrogen 2.900 N/A LEU 212.A N LYS 208.A O no hydrogen 2.799 N/A ASP 213.A N LYS 209.A O no hydrogen 3.120 N/A ILE 214.A N TYR 210.A O no hydrogen 3.092 N/A ILE 215.A N ALA 211.A O no hydrogen 2.904 N/A LYS 216.A N LEU 212.A O no hydrogen 2.953 N/A GLU 217.A N ASP 213.A O no hydrogen 3.002 N/A THR 218.A N ILE 214.A O no hydrogen 2.969 N/A THR 218.A OG1 ILE 214.A O no hydrogen 3.371 N/A THR 218.A OG1 ILE 215.A O no hydrogen 2.946 N/A HIS 219.A N ILE 215.A O no hydrogen 2.897 N/A HIS 219.A ND1 GLN 98.A O no hydrogen 2.717 N/A ASP 220.A N LYS 216.A O no hydrogen 2.909 N/A SER 221.A N GLU 217.A O no hydrogen 2.991 N/A SER 221.A OG GLU 217.A O no hydrogen 3.400 N/A TRP 222.A N THR 218.A O no hydrogen 3.045 N/A LYS 223.A N HIS 219.A O no hydrogen 2.933 N/A GLN 224.A N ASP 220.A O no hydrogen 3.235 N/A LEU 225.A N SER 221.A O no hydrogen 3.000 N/A ILE 226.A N TRP 222.A O no hydrogen 2.888 N/A ALA 227.A N LYS 223.A O no hydrogen 3.157 N/A GLY 228.A N LEU 225.A O no hydrogen 2.977 N/A LYS 229.A N GLN 224.A O no hydrogen 2.830 N/A SER 230.A OG ASP 232.A O no hydrogen 3.364 N/A ILE 236.A N SER 233.A O no hydrogen 2.772 N/A ASP 237.A N LYS 61.A O no hydrogen 2.783 N/A THR 239.A N ASP 237.A OD1 no hydrogen 2.944 N/A THR 239.A OG1 ASP 237.A OD1 no hydrogen 2.601 N/A VAL 241.A N ASP 31.A OD1 no hydrogen 3.271 N/A VAL 241.A N ASP 31.A OD2 no hydrogen 2.859 N/A THR 242.A N ASP 31.A OD1 no hydrogen 2.987 N/A THR 242.A OG1 ASP 31.A OD1 no hydrogen 2.629 N/A THR 246.A N LEU 243.A O no hydrogen 3.048 N/A THR 246.A OG1 ASN 240.A OD1 no hydrogen 2.940 N/A THR 246.A OG1 LEU 243.A O no hydrogen 2.633 N/A THR 248.A OG1 LEU 238.A O no hydrogen 2.693 N/A THR 248.A OG1 ASN 240.A OD1 no hydrogen 3.530 N/A TYR 249.A N THR 246.A O no hydrogen 3.415 N/A SER 250.A N ASN 240.A O no hydrogen 2.868 N/A ALA 253.A N SER 250.A O no hydrogen 3.154 N/A SER 254.A OG PRO 25.A O no hydrogen 2.618 N/A ALA 256.A N ALA 252.A O no hydrogen 3.353 N/A ILE 257.A N SER 254.A O no hydrogen 3.341 N/A SER 261.A N GLN 6.A O no hydrogen 2.959 N/A LYS 263.A N GLY 8.A O no hydrogen 3.432 N/A ALA 266.A N LYS 10.A O no hydrogen 2.885 N/A SER 271.A N ASP 269.A OD2 no hydrogen 2.890 N/A SER 271.A OG ASP 269.A OD2 no hydrogen 2.770 N/A ILE 272.A N ASP 269.A O no hydrogen 2.981 N/A ASP 273.A N LYS 270.A O no hydrogen 2.969 N/A LYS 274.A N SER 271.A O no hydrogen 3.094 N/A TRP 275.A NE1 HIS 86.A O no hydrogen 2.828 N/A PHE 276.A N ASN 82.A O no hydrogen 2.823 N/A