Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2iku_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 3.A N VAL 149.A O no hydrogen 2.815 N/A THR 3.A OG1 VAL 149.A O no hydrogen 3.484 N/A SER 5.A N LEU 175.A O no hydrogen 3.047 N/A SER 5.A OG GLY 97.A O no hydrogen 3.029 N/A VAL 7.A N ILE 173.A O no hydrogen 2.959 N/A LEU 9.A N GLY 171.A O no hydrogen 2.874 N/A THR 10.A N TYR 18.A O no hydrogen 2.752 N/A ASN 11.A ND2 ASP 14.A OD2 no hydrogen 2.870 N/A TYR 12.A N GLN 16.A O no hydrogen 2.814 N/A ASP 14.A N ASN 11.A OD1 no hydrogen 2.956 N/A THR 15.A N TYR 12.A O no hydrogen 2.836 N/A THR 15.A OG1 TYR 12.A O no hydrogen 3.309 N/A GLN 16.A N TYR 12.A O no hydrogen 3.198 N/A GLN 16.A NE2 LEU 118.A O no hydrogen 2.979 N/A TYR 17.A OH ASN 160.A O no hydrogen 2.822 N/A TYR 18.A N THR 10.A O no hydrogen 3.167 N/A GLY 19.A N VAL 32.A O no hydrogen 2.958 N/A ILE 21.A N PHE 30.A O no hydrogen 3.069 N/A GLY 22.A N THR 95.A O no hydrogen 3.212 N/A ILE 23.A N GLN 28.A O no hydrogen 2.757 N/A GLY 24.A N ILE 93.A O no hydrogen 2.975 N/A THR 25.A N SER 66.A OG no hydrogen 3.129 N/A THR 25.A OG1 SER 68.A OG no hydrogen 2.569 N/A GLN 28.A N ILE 23.A O no hydrogen 2.749 N/A GLN 28.A NE2 ASP 62.A O no hydrogen 2.702 N/A PHE 30.A N ILE 21.A O no hydrogen 2.982 N/A LYS 31.A N ASP 122.A OD1 no hydrogen 2.854 N/A VAL 32.A N GLY 19.A O no hydrogen 2.825 N/A VAL 33.A N GLY 123.A O no hydrogen 3.168 N/A ASP 35.A N VAL 125.A O no hydrogen 2.954 N/A THR 36.A N THR 224.A OG1 no hydrogen 2.727 N/A THR 36.A OG1 VAL 222.A O no hydrogen 2.794 N/A THR 36.A OG1 THR 224.A OG1 no hydrogen 3.116 N/A GLY 37.A N ASP 35.A OD2 no hydrogen 2.617 N/A SER 38.A N ASP 35.A O no hydrogen 3.517 N/A SER 38.A OG ASP 35.A OD1 no hydrogen 2.604 N/A SER 39.A OG PHE 129.A O no hydrogen 2.765 N/A ASN 40.A ND2 ILE 134.A O no hydrogen 2.893 N/A TRP 42.A N VAL 124.A O no hydrogen 3.055 N/A TRP 42.A NE1 TYR 80.A OH no hydrogen 2.812 N/A VAL 43.A N GLY 106.A O no hydrogen 3.035 N/A SER 45.A N VAL 108.A O no hydrogen 2.855 N/A SER 45.A OG GLU 107.A OE2 no hydrogen 2.752 N/A SER 46.A N PHE 61.A O no hydrogen 2.792 N/A SER 46.A OG PHE 61.A O no hydrogen 3.249 N/A LYS 47.A N SER 45.A OG no hydrogen 3.018 N/A CYS 48.A N SER 45.A O no hydrogen 2.951 N/A CYS 48.A SG SER 49.A O no hydrogen 3.504 N/A CYS 48.A SG THR 109.A O no hydrogen 3.558 N/A ARG 50.A NH2 SER 46.A O no hydrogen 3.008 N/A ARG 50.A NH2 CYS 48.A O no hydrogen 3.035 N/A LEU 51.A N SER 49.A OG no hydrogen 3.252 N/A TYR 52.A N SER 49.A O no hydrogen 2.938 N/A CYS 55.A N TYR 52.A O no hydrogen 2.838 N/A TYR 57.A N THR 53.A O no hydrogen 3.225 N/A TYR 57.A N ALA 54.A O no hydrogen 3.280 N/A HIS 58.A ND1 ALA 54.A O no hydrogen 2.725 N/A HIS 58.A NE2 ALA 119.A O no hydrogen 2.856 N/A LYS 59.A N ASP 122.A OD2 no hydrogen 2.850 N/A LYS 59.A NZ THR 29.A O no hydrogen 2.797 N/A LYS 59.A NZ THR 29.A OG1 no hydrogen 2.933 N/A PHE 61.A N PRO 44.A O no hydrogen 2.745 N/A ASP 62.A N GLN 28.A OE1 no hydrogen 2.828 N/A ASP 65.A N ASP 62.A O no hydrogen 3.162 N/A SER 66.A N ALA 63.A O no hydrogen 2.998 N/A SER 66.A OG SER 68.A OG no hydrogen 3.104 N/A SER 66.A OG ASP 92.A OD1 no hydrogen 3.385 N/A SER 66.A OG ASP 92.A OD2 no hydrogen 2.569 N/A SER 67.A N THR 25.A O no hydrogen 2.936 N/A SER 67.A OG THR 25.A O no hydrogen 3.476 N/A SER 68.A OG THR 25.A OG1 no hydrogen 2.569 N/A SER 68.A OG SER 66.A OG no hydrogen 3.104 N/A SER 68.A OG ASP 92.A OD1 no hydrogen 2.563 N/A LYS 70.A N GLN 91.A O no hydrogen 2.802 N/A GLY 73.A N LEU 89.A O no hydrogen 2.855 N/A THR 74.A N ASN 72.A OD1 no hydrogen 2.965 N/A THR 74.A OG1 ASN 72.A OD1 no hydrogen 2.739 N/A LEU 76.A N GLY 87.A O no hydrogen 3.111 N/A THR 77.A OG1 SER 86.A OG no hydrogen 3.055 N/A LEU 78.A N VAL 85.A O no hydrogen 2.837 N/A TYR 80.A N GLY 83.A O no hydrogen 2.812 N/A GLY 83.A N TYR 80.A O no hydrogen 3.255 N/A VAL 85.A N LEU 78.A O no hydrogen 3.053 N/A SER 86.A N GLU 110.A O no hydrogen 3.200 N/A SER 86.A OG THR 77.A OG1 no hydrogen 3.055 N/A SER 86.A OG GLU 110.A OE1 no hydrogen 3.321 N/A GLY 87.A N LEU 76.A O no hydrogen 2.935 N/A PHE 88.A N GLU 107.A O no hydrogen 3.073 N/A LEU 89.A N THR 74.A O no hydrogen 2.776 N/A SER 90.A N PHE 105.A O no hydrogen 2.730 N/A SER 90.A OG GLU 107.A OE1 no hydrogen 2.689 N/A GLN 91.A N LYS 70.A O no hydrogen 2.954 N/A ASP 92.A N GLN 103.A O no hydrogen 3.145 N/A ILE 93.A N ASP 92.A OD1 no hydrogen 2.761 N/A ILE 94.A N VAL 101.A O no hydrogen 2.783 N/A THR 95.A N GLY 22.A O no hydrogen 2.962 N/A THR 95.A OG1 GLY 22.A O no hydrogen 3.378 N/A VAL 96.A N ILE 99.A O no hydrogen 2.887 N/A ILE 99.A N VAL 96.A O no hydrogen 3.046 N/A VAL 101.A N ILE 94.A O no hydrogen 2.855 N/A GLN 103.A N ASP 92.A O no hydrogen 2.959 N/A GLN 103.A NE2 MET 104.A O no hydrogen 2.874 N/A GLN 103.A NE2 THR 138.A O no hydrogen 3.073 N/A PHE 105.A N SER 90.A O no hydrogen 2.680 N/A GLY 106.A N VAL 41.A O no hydrogen 2.705 N/A GLU 107.A N PHE 88.A O no hydrogen 2.780 N/A VAL 108.A N VAL 43.A O no hydrogen 3.021 N/A THR 109.A N SER 86.A O no hydrogen 2.892 N/A GLU 110.A N SER 86.A O no hydrogen 2.979 N/A PHE 116.A N PRO 112.A O no hydrogen 2.972 N/A MET 117.A N ALA 113.A O no hydrogen 2.948 N/A LEU 118.A N PRO 115.A O no hydrogen 2.795 N/A ALA 119.A N PHE 116.A O no hydrogen 3.098 N/A GLU 120.A N GLN 16.A OE1 no hydrogen 2.807 N/A ASP 122.A N LYS 31.A O no hydrogen 2.749 N/A GLY 123.A N LYS 31.A O no hydrogen 3.058 N/A VAL 124.A N TRP 42.A O no hydrogen 3.062 N/A VAL 125.A N VAL 33.A O no hydrogen 2.950 N/A GLY 126.A N ASN 40.A O no hydrogen 2.861 N/A MET 127.A N ASP 35.A O no hydrogen 2.646 N/A GLY 128.A N SER 38.A O no hydrogen 2.792 N/A GLU 131.A N GLU 131.A OE1 no hydrogen 2.781 N/A GLN 132.A N PHE 129.A O no hydrogen 3.055 N/A ALA 133.A N ILE 130.A O no hydrogen 2.705 N/A ILE 134.A N ASN 40.A OD1 no hydrogen 2.819 N/A ARG 136.A N ALA 133.A O no hydrogen 3.258 N/A ASN 143.A N PRO 139.A O no hydrogen 3.064 N/A ILE 144.A N ILE 140.A O no hydrogen 2.854 N/A ILE 145.A N PHE 141.A O no hydrogen 2.920 N/A SER 146.A N ASP 142.A O no hydrogen 3.140 N/A SER 146.A OG ASP 142.A O no hydrogen 3.559 N/A GLN 147.A N ILE 144.A O no hydrogen 3.132 N/A GLN 147.A NE2 THR 100.A O no hydrogen 2.882 N/A GLY 148.A N ILE 145.A O no hydrogen 2.853 N/A LYS 151.A N THR 3.A O no hydrogen 3.070 N/A PHE 155.A N PHE 324.A O no hydrogen 3.035 N/A SER 156.A N VAL 174.A O no hydrogen 3.040 N/A SER 156.A OG GLY 177.A O no hydrogen 2.664 N/A SER 156.A OG SER 178.A OG no hydrogen 2.703 N/A PHE 157.A N THR 322.A O no hydrogen 2.862 N/A TYR 158.A N GLN 172.A O no hydrogen 2.768 N/A TYR 159.A OH THR 224.A O no hydrogen 2.482 N/A ASN 160.A N GLY 170.A O no hydrogen 2.876 N/A ASN 160.A ND2 LEU 169.A O no hydrogen 2.939 N/A ASN 165.A N SER 163.A OG no hydrogen 2.805 N/A GLY 171.A N LEU 9.A O no hydrogen 3.082 N/A GLN 172.A N TYR 158.A O no hydrogen 2.868 N/A GLN 172.A NE2 ASP 179.A OD2 no hydrogen 3.227 N/A ILE 173.A N VAL 7.A O no hydrogen 3.142 N/A VAL 174.A N SER 156.A O no hydrogen 3.023 N/A LEU 175.A N SER 5.A O no hydrogen 2.603 N/A GLY 176.A N VAL 154.A O no hydrogen 2.765 N/A SER 178.A OG SER 156.A OG no hydrogen 2.703 N/A SER 178.A OG GLU 323.A OE2 no hydrogen 2.861 N/A ASP 179.A N TYR 321.A OH no hydrogen 2.925 N/A GLN 181.A N ASP 179.A OD1 no hydrogen 2.885 N/A HIS 182.A N ASP 179.A O no hydrogen 2.932 N/A GLU 184.A N LEU 335.A O no hydrogen 2.890 N/A HIS 188.A N PHE 333.A O no hydrogen 2.857 N/A TYR 189.A OH GLU 323.A OE1 no hydrogen 2.854 N/A ILE 190.A N ILE 331.A O no hydrogen 2.846 N/A LEU 192.A N ASN 329.A O no hydrogen 3.204 N/A ILE 193.A N GLN 199.A O no hydrogen 3.203 N/A THR 195.A OG1 ASN 329.A OD1 no hydrogen 2.808 N/A TRP 198.A NE1 MET 127.A O no hydrogen 3.077 N/A GLN 199.A NE2 THR 306.A O no hydrogen 3.061 N/A ILE 200.A N ALA 220.A O no hydrogen 2.948 N/A GLN 201.A NE2 MET 202.A O no hydrogen 3.539 N/A MET 202.A N CYS 218.A O no hydrogen 2.897 N/A LYS 203.A N HIS 268.A O no hydrogen 2.936 N/A VAL 205.A N LEU 213.A O no hydrogen 3.208 N/A SER 206.A N SER 266.A O no hydrogen 2.993 N/A VAL 207.A N SER 210.A O no hydrogen 3.184 N/A GLY 208.A N ASP 264.A O no hydrogen 2.884 N/A SER 210.A OG VAL 207.A O no hydrogen 3.555 N/A LEU 213.A N VAL 205.A O no hydrogen 3.358 N/A CYS 214.A SG MET 202.A O no hydrogen 3.301 N/A GLY 217.A N CYS 214.A O no hydrogen 3.187 N/A CYS 218.A N MET 202.A O no hydrogen 2.813 N/A CYS 218.A SG MET 202.A O no hydrogen 3.936 N/A ALA 220.A N ILE 200.A O no hydrogen 2.967 N/A LEU 221.A N TRP 310.A O no hydrogen 2.714 N/A VAL 222.A N TRP 198.A O no hydrogen 2.894 N/A ASP 223.A N LEU 312.A O no hydrogen 3.190 N/A THR 224.A N THR 36.A OG1 no hydrogen 2.775 N/A THR 224.A OG1 PHE 34.A O no hydrogen 2.758 N/A THR 224.A OG1 THR 36.A OG1 no hydrogen 3.116 N/A GLY 225.A N ASP 223.A OD2 no hydrogen 2.963 N/A ALA 226.A N ASP 223.A O no hydrogen 3.103 N/A SER 227.A OG THR 15.A O no hydrogen 2.413 N/A ILE 229.A N ALA 296.A O no hydrogen 3.349 N/A SER 230.A N ALA 311.A O no hydrogen 2.840 N/A GLY 231.A N HIS 298.A O no hydrogen 3.244 N/A SER 232.A OG SER 235.A OG no hydrogen 2.226 N/A THR 233.A N ASP 301.A OD2 no hydrogen 3.108 N/A THR 233.A OG1 ASP 301.A OD1 no hydrogen 2.394 N/A SER 235.A N SER 232.A OG no hydrogen 2.901 N/A SER 235.A OG SER 232.A OG no hydrogen 2.226 N/A ILE 236.A N SER 232.A O no hydrogen 2.804 N/A GLU 237.A N THR 233.A O no hydrogen 2.888 N/A LYS 238.A N SER 234.A O no hydrogen 3.322 N/A LEU 239.A N SER 235.A O no hydrogen 3.131 N/A MET 240.A N ILE 236.A O no hydrogen 2.686 N/A GLU 241.A N GLU 237.A O no hydrogen 2.914 N/A ALA 242.A N LYS 238.A O no hydrogen 3.206 N/A LEU 243.A N LEU 239.A O no hydrogen 3.091 N/A GLY 244.A N GLU 241.A O no hydrogen 3.075 N/A ALA 245.A N MET 240.A O no hydrogen 2.896 N/A LYS 246.A N VAL 253.A O no hydrogen 2.738 N/A LYS 247.A NZ ARG 248.A O no hydrogen 2.871 N/A ARG 248.A N ASP 251.A O no hydrogen 2.839 N/A ARG 248.A NE ASP 251.A OD1 no hydrogen 3.010 N/A ARG 248.A NH1 ASP 251.A OD1 no hydrogen 3.564 N/A ARG 248.A NH1 ASP 251.A OD2 no hydrogen 3.160 N/A VAL 253.A N LYS 246.A O no hydrogen 2.891 N/A VAL 254.A N CYS 293.A O no hydrogen 3.268 N/A CYS 256.A N LYS 291.A O no hydrogen 3.109 N/A GLU 258.A N LYS 255.A O no hydrogen 2.882 N/A GLY 259.A N CYS 256.A O no hydrogen 2.993 N/A THR 261.A OG1 GLU 258.A O no hydrogen 3.216 N/A LEU 262.A N GLY 259.A O no hydrogen 2.989 N/A ILE 265.A N LEU 276.A O no hydrogen 3.012 N/A SER 266.A N SER 206.A O no hydrogen 2.884 N/A SER 266.A OG THR 275.A OG1 no hydrogen 2.798 N/A PHE 267.A N TYR 274.A O no hydrogen 2.856 N/A HIS 268.A N GLY 204.A O no hydrogen 2.784 N/A LEU 269.A N LYS 272.A O no hydrogen 2.989 N/A LYS 272.A N LEU 269.A O no hydrogen 3.032 N/A TYR 274.A N PHE 267.A O no hydrogen 2.811 N/A THR 275.A OG1 SER 266.A OG no hydrogen 2.798 N/A LEU 276.A N ILE 265.A O no hydrogen 2.885 N/A THR 277.A N ASP 280.A OD2 no hydrogen 2.537 N/A THR 277.A OG1 ASP 280.A OD2 no hydrogen 2.919 N/A SER 278.A OG PRO 260.A O no hydrogen 3.091 N/A ASP 280.A N THR 277.A O no hydrogen 2.833 N/A TYR 281.A N SER 278.A O no hydrogen 2.911 N/A TYR 281.A OH PRO 263.A O no hydrogen 2.694 N/A VAL 282.A N SER 278.A O no hydrogen 2.802 N/A PHE 283.A N THR 294.A O no hydrogen 2.938 N/A GLN 284.A N VAL 282.A O no hydrogen 2.974 N/A GLN 284.A NE2 CYS 256.A O no hydrogen 3.040 N/A GLN 284.A NE2 SER 286.A O no hydrogen 2.684 N/A SER 288.A N SER 286.A OG no hydrogen 2.933 N/A LYS 290.A N SER 288.A OG no hydrogen 2.932 N/A CYS 293.A N VAL 254.A O no hydrogen 3.062 N/A CYS 293.A SG PHE 283.A O no hydrogen 3.473 N/A CYS 293.A SG SER 286.A O no hydrogen 4.023 N/A THR 294.A OG1 ASP 251.A OD2 no hydrogen 3.356 N/A LEU 295.A N TYR 252.A O no hydrogen 3.196 N/A ALA 296.A N TYR 281.A O no hydrogen 2.672 N/A HIS 298.A N ILE 229.A O no hydrogen 2.910 N/A MET 300.A N GLY 231.A O no hydrogen 2.951 N/A GLY 307.A N PRO 303.A O no hydrogen 2.905 N/A THR 309.A OG1 TRP 310.A O no hydrogen 2.715 N/A TRP 310.A N LEU 219.A O no hydrogen 2.802 N/A ALA 311.A N SER 230.A O no hydrogen 2.742 N/A LEU 312.A N LEU 221.A O no hydrogen 2.656 N/A GLY 313.A N TYR 228.A O no hydrogen 2.927 N/A ALA 314.A N ALA 226.A O no hydrogen 3.049 N/A THR 315.A OG1 SER 227.A O no hydrogen 3.473 N/A THR 315.A OG1 ALA 296.A O no hydrogen 2.869 N/A PHE 316.A N GLY 313.A O no hydrogen 2.877 N/A ILE 317.A N GLY 313.A O no hydrogen 3.048 N/A ARG 318.A N ALA 314.A O no hydrogen 2.993 N/A ARG 318.A NH2 ASP 14.A O no hydrogen 2.919 N/A ARG 318.A NH2 TYR 17.A OH no hydrogen 3.259 N/A LYS 319.A N PHE 316.A O no hydrogen 3.215 N/A LYS 319.A NZ THR 275.A O no hydrogen 2.576 N/A PHE 320.A N PHE 316.A O no hydrogen 3.089 N/A THR 322.A N PHE 157.A O no hydrogen 3.333 N/A THR 322.A OG1 PHE 320.A O no hydrogen 2.847 N/A GLU 323.A N GLY 332.A O no hydrogen 2.921 N/A PHE 324.A N PHE 155.A O no hydrogen 2.644 N/A ASP 325.A N ARG 330.A O no hydrogen 2.758 N/A ARG 326.A N ASP 153.A O no hydrogen 2.954 N/A ASN 328.A N ASP 325.A OD2 no hydrogen 3.141 N/A ARG 330.A N ASP 325.A O no hydrogen 2.948 N/A ARG 330.A NE ASP 325.A OD1 no hydrogen 3.298 N/A ILE 331.A N ILE 190.A O no hydrogen 3.020 N/A GLY 332.A N GLU 323.A O no hydrogen 2.909 N/A PHE 333.A N HIS 188.A O no hydrogen 2.923 N/A ALA 334.A N TYR 321.A O no hydrogen 2.958 N/A ALA 336.A N LYS 319.A O no hydrogen 2.944 N/A ARG 337.A N HIS 182.A O no hydrogen 3.026 N/A ARG 337.A NE TYR 183.A O no hydrogen 3.058 N/A ARG 337.A NH2 TYR 183.A O no hydrogen 3.399 N/A