Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2iwm_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 2.A N ASP 23.A O no hydrogen 2.947 N/A GLY 3.A N ASP 23.A O no hydrogen 3.223 N/A SER 4.A N ASN 178.A OD1 no hydrogen 3.002 N/A SER 4.A OG GLY 3.A O no hydrogen 1.921 N/A SER 5.A N THR 21.A OG1 no hydrogen 3.083 N/A SER 6.A N MET 176.A O no hydrogen 2.841 N/A SER 6.A OG MET 176.A O no hydrogen 2.895 N/A LEU 7.A N ALA 19.A O no hydrogen 3.067 N/A SER 8.A N GLY 174.A O no hydrogen 2.943 N/A SER 8.A OG SER 156.A OG no hydrogen 3.224 N/A ILE 9.A N LEU 17.A O no hydrogen 2.845 N/A ARG 10.A NH1 SER 16.A OG no hydrogen 2.692 N/A ARG 10.A NH1 ALA 152.A O no hydrogen 2.895 N/A THR 11.A N LYS 15.A O no hydrogen 2.761 N/A THR 11.A OG1 LYS 15.A O no hydrogen 3.468 N/A THR 12.A N ALA 245.A O no hydrogen 2.967 N/A ASP 13.A N THR 11.A OG1 no hydrogen 2.981 N/A ASP 14.A N THR 11.A O no hydrogen 3.238 N/A LYS 15.A N THR 11.A OG1 no hydrogen 2.978 N/A LYS 15.A NZ GLU 248.A OE1 no hydrogen 2.621 N/A SER 16.A N GLN 288.A OE1 no hydrogen 2.802 N/A SER 16.A OG ALA 152.A O no hydrogen 3.555 N/A LEU 17.A N ILE 9.A O no hydrogen 2.792 N/A PHE 18.A N MET 285.A O no hydrogen 2.959 N/A ALA 19.A N LEU 7.A O no hydrogen 2.916 N/A ARG 20.A N SER 283.A O no hydrogen 2.963 N/A ARG 20.A NE THR 21.A O no hydrogen 2.842 N/A ARG 20.A NH1 TYR 71.A O no hydrogen 3.004 N/A ARG 20.A NH1 ASP 72.A OD2 no hydrogen 2.801 N/A ARG 20.A NH2 MET 83.A O no hydrogen 3.120 N/A THR 21.A N SER 5.A O no hydrogen 2.952 N/A THR 21.A OG1 SER 5.A O no hydrogen 3.532 N/A MET 22.A N TYR 281.A O no hydrogen 2.925 N/A ASP 23.A N GLY 3.A O no hydrogen 3.078 N/A PHE 24.A N TYR 278.A O no hydrogen 2.991 N/A SER 30.A OG TYR 71.A OH no hydrogen 2.841 N/A LYS 31.A N GLY 61.A O no hydrogen 3.079 N/A LYS 31.A NZ GLU 321.A OE2 no hydrogen 3.376 N/A VAL 32.A N PHE 320.A O no hydrogen 3.121 N/A ILE 33.A N GLY 59.A O no hydrogen 2.713 N/A ILE 34.A N ILE 318.A O no hydrogen 2.696 N/A VAL 35.A N PHE 57.A O no hydrogen 2.913 N/A ARG 37.A N LEU 312.A O no hydrogen 2.869 N/A ASN 38.A N ASN 53.A O no hydrogen 2.791 N/A ASN 38.A ND2 ASN 52.A OD1 no hydrogen 3.026 N/A GLY 40.A N ASN 53.A OD1 no hydrogen 2.878 N/A ILE 41.A N ILE 51.A O no hydrogen 2.892 N/A ARG 42.A N SER 67.A OG no hydrogen 2.773 N/A ARG 42.A NE LEU 44.A O no hydrogen 3.189 N/A ARG 42.A NH2 LEU 44.A O no hydrogen 3.367 N/A GLU 45.A N GLU 134.A OE1 no hydrogen 2.578 N/A LYS 46.A N GLU 134.A OE2 no hydrogen 3.073 N/A ILE 51.A N ILE 41.A O no hydrogen 2.842 N/A ASN 53.A ND2 PRO 36.A O no hydrogen 2.913 N/A ASN 53.A ND2 TYR 55.A O no hydrogen 3.013 N/A TYR 55.A N GLY 114.A O no hydrogen 2.706 N/A ALA 56.A N GLU 76.A OE2 no hydrogen 2.883 N/A PHE 57.A N VAL 35.A O no hydrogen 3.036 N/A VAL 58.A N VAL 74.A O no hydrogen 3.095 N/A GLY 59.A N ILE 33.A O no hydrogen 3.117 N/A GLY 61.A N LYS 31.A O no hydrogen 2.943 N/A SER 62.A N VAL 69.A O no hydrogen 3.036 N/A ASP 64.A N SER 62.A OG no hydrogen 3.059 N/A THR 66.A OG1 GLU 45.A OE1 no hydrogen 2.762 N/A THR 66.A OG1 GLU 45.A OE2 no hydrogen 2.892 N/A SER 67.A N TYR 107.A OH no hydrogen 3.076 N/A VAL 69.A N SER 62.A O no hydrogen 3.043 N/A LEU 70.A N SER 110.A OG no hydrogen 3.196 N/A TYR 71.A N MET 60.A O no hydrogen 2.754 N/A TYR 71.A OH SER 30.A OG no hydrogen 2.841 N/A GLY 73.A N GLY 81.A O no hydrogen 3.100 N/A VAL 74.A N VAL 58.A O no hydrogen 2.919 N/A ASN 75.A N LEU 79.A O no hydrogen 2.824 N/A ASN 75.A ND2 LEU 113.A O no hydrogen 2.719 N/A ASN 75.A ND2 CYS 116.A O no hydrogen 2.874 N/A GLU 76.A N ALA 56.A O no hydrogen 2.774 N/A LYS 77.A N ASN 75.A OD1 no hydrogen 2.839 N/A GLY 78.A N ASN 75.A O no hydrogen 2.984 N/A LEU 79.A N ASN 75.A OD1 no hydrogen 3.071 N/A MET 80.A N THR 150.A O no hydrogen 2.939 N/A GLY 81.A N GLY 73.A O no hydrogen 3.090 N/A ALA 82.A N THR 148.A O no hydrogen 2.841 N/A MET 83.A N TYR 71.A O no hydrogen 2.953 N/A LEU 84.A N HIS 146.A O no hydrogen 2.963 N/A TYR 86.A N PRO 144.A O no hydrogen 2.904 N/A TYR 86.A OH ASP 162.A OD1 no hydrogen 2.626 N/A THR 88.A OG1 ALA 87.A O no hydrogen 2.634 N/A PHE 89.A N TYR 86.A O no hydrogen 3.196 N/A ALA 90.A N TYR 86.A O no hydrogen 3.144 N/A THR 91.A N PRO 161.A O no hydrogen 2.852 N/A THR 91.A OG1 PHE 89.A O no hydrogen 3.226 N/A TYR 92.A OH PRO 143.A O no hydrogen 2.733 N/A ALA 93.A N LEU 131.A O no hydrogen 3.114 N/A THR 100.A N LYS 97.A O no hydrogen 3.043 N/A THR 100.A OG1 LYS 97.A O no hydrogen 2.882 N/A THR 100.A OG1 THR 130.A OG1 no hydrogen 2.980 N/A ARG 101.A N SER 128.A O no hydrogen 3.102 N/A ILE 103.A N THR 130.A O no hydrogen 2.847 N/A ASN 104.A N LEU 43.A O no hydrogen 2.835 N/A ASN 104.A ND2 GLU 134.A OE1 no hydrogen 3.289 N/A ASN 104.A ND2 ALA 135.A O no hydrogen 3.669 N/A VAL 106.A N ASN 104.A OD1 no hydrogen 2.709 N/A TYR 107.A N ASN 104.A O no hydrogen 2.952 N/A TYR 107.A OH GLU 45.A OE2 no hydrogen 2.715 N/A TYR 107.A OH SER 67.A O no hydrogen 3.366 N/A VAL 108.A N PRO 105.A O no hydrogen 3.456 N/A SER 110.A OG PRO 68.A O no hydrogen 2.978 N/A GLN 111.A N TYR 107.A O no hydrogen 2.841 N/A GLN 111.A NE2 ILE 41.A O no hydrogen 2.911 N/A GLN 111.A NE2 ARG 42.A O no hydrogen 3.169 N/A VAL 112.A N VAL 108.A O no hydrogen 2.895 N/A LEU 113.A N ILE 109.A O no hydrogen 2.812 N/A GLY 114.A N SER 110.A O no hydrogen 3.079 N/A ASN 115.A N VAL 112.A O no hydrogen 3.141 N/A ASN 115.A ND2 ASN 52.A O no hydrogen 3.241 N/A CYS 116.A N VAL 112.A O no hydrogen 3.105 N/A VAL 117.A N ASP 121.A OD2 no hydrogen 3.146 N/A THR 118.A N ASP 121.A OD2 no hydrogen 3.121 N/A VAL 119.A N ASP 151.A OD2 no hydrogen 2.819 N/A ASP 121.A N THR 118.A OG1 no hydrogen 3.221 N/A VAL 122.A N THR 118.A O no hydrogen 3.168 N/A ILE 123.A N VAL 119.A O no hydrogen 3.234 N/A GLU 124.A N ASP 120.A O no hydrogen 3.020 N/A LYS 125.A N ASP 121.A O no hydrogen 2.822 N/A LEU 126.A N VAL 122.A O no hydrogen 3.008 N/A THR 127.A N GLU 124.A O no hydrogen 3.218 N/A THR 127.A OG1 GLU 124.A O no hydrogen 2.944 N/A SER 128.A N LYS 125.A O no hydrogen 2.945 N/A SER 128.A OG LYS 125.A O no hydrogen 2.746 N/A TYR 129.A N LEU 126.A O no hydrogen 3.040 N/A THR 130.A N ARG 101.A O no hydrogen 2.728 N/A THR 130.A OG1 THR 100.A OG1 no hydrogen 2.980 N/A THR 130.A OG1 TYR 129.A O no hydrogen 3.228 N/A LEU 132.A N ILE 103.A O no hydrogen 3.042 N/A ASN 133.A N ALA 93.A O no hydrogen 2.902 N/A ILE 138.A N ASN 136.A OD1 no hydrogen 2.856 N/A LEU 139.A N ASN 136.A OD1 no hydrogen 3.077 N/A GLY 140.A N ASN 136.A O no hydrogen 2.619 N/A LEU 145.A N TYR 92.A OH no hydrogen 2.914 N/A HIS 146.A N LEU 84.A O no hydrogen 2.870 N/A HIS 146.A ND1 GLU 160.A OE2 no hydrogen 2.498 N/A HIS 146.A NE2 THR 177.A O no hydrogen 2.698 N/A TYR 147.A N ILE 159.A O no hydrogen 2.976 N/A TYR 147.A OH PRO 105.A O no hydrogen 2.697 N/A THR 148.A N ALA 82.A O no hydrogen 2.973 N/A THR 148.A OG1 ILE 157.A O no hydrogen 3.056 N/A PHE 149.A N ILE 157.A O no hydrogen 3.197 N/A THR 150.A N MET 80.A O no hydrogen 2.740 N/A THR 150.A OG1 SER 156.A OG no hydrogen 2.566 N/A ASP 151.A N GLU 155.A O no hydrogen 3.205 N/A SER 153.A N ASP 151.A OD1 no hydrogen 3.023 N/A SER 153.A OG ASP 151.A OD1 no hydrogen 2.735 N/A GLY 154.A N ASP 151.A O no hydrogen 2.930 N/A GLU 155.A N SER 153.A OG no hydrogen 3.379 N/A SER 156.A OG SER 8.A OG no hydrogen 3.224 N/A SER 156.A OG THR 150.A OG1 no hydrogen 2.566 N/A ILE 157.A N PHE 149.A O no hydrogen 2.999 N/A VAL 158.A N HIS 169.A O no hydrogen 3.079 N/A ILE 159.A N TYR 147.A O no hydrogen 2.858 N/A GLU 160.A N THR 167.A O no hydrogen 2.929 N/A ASP 162.A N GLY 165.A O no hydrogen 2.905 N/A GLY 165.A N ASP 162.A O no hydrogen 2.881 N/A THR 167.A N GLU 160.A O no hydrogen 2.910 N/A THR 167.A OG1 ASP 162.A OD2 no hydrogen 2.583 N/A HIS 169.A N VAL 158.A O no hydrogen 2.810 N/A ARG 170.A NH1 ASP 120.A OD2 no hydrogen 3.567 N/A ARG 170.A NH2 ASP 120.A OD2 no hydrogen 2.968 N/A LYS 171.A N GLU 155.A OE2 no hydrogen 3.065 N/A THR 172.A N SER 156.A O no hydrogen 3.161 N/A THR 172.A OG1 SER 156.A O no hydrogen 3.369 N/A ILE 173.A N TYR 182.A OH no hydrogen 3.060 N/A GLY 174.A N THR 172.A OG1 no hydrogen 3.286 N/A MET 176.A N SER 6.A O no hydrogen 2.946 N/A THR 177.A OG1 PRO 228.A O no hydrogen 2.688 N/A ASN 178.A ND2 TYR 85.A O no hydrogen 2.965 N/A SER 179.A OG ALA 87.A O no hydrogen 2.631 N/A TYR 182.A N GLU 160.A OE1 no hydrogen 2.746 N/A TYR 182.A OH GLN 186.A OE1 no hydrogen 2.897 N/A HIS 185.A N GLY 181.A O no hydrogen 3.397 N/A HIS 185.A NE2 ASN 178.A O no hydrogen 2.903 N/A GLN 186.A N TYR 182.A O no hydrogen 3.022 N/A THR 187.A N GLU 183.A O no hydrogen 2.922 N/A THR 187.A OG1 GLU 183.A O no hydrogen 3.119 N/A ASN 188.A N TRP 184.A O no hydrogen 2.855 N/A LEU 189.A N HIS 185.A O no hydrogen 2.963 N/A ARG 190.A N THR 187.A O no hydrogen 3.076 N/A ALA 191.A N ASN 188.A O no hydrogen 3.079 N/A TYR 192.A N LEU 189.A O no hydrogen 2.984 N/A VAL 195.A N TYR 192.A O no hydrogen 3.032 N/A THR 196.A N GLY 218.A O no hydrogen 3.039 N/A THR 196.A OG1 ASN 198.A O no hydrogen 3.408 N/A ILE 203.A N LEU 210.A O no hydrogen 3.367 N/A MET 205.A N LEU 208.A O no hydrogen 2.856 N/A LEU 208.A N MET 205.A O no hydrogen 3.059 N/A LEU 210.A N ILE 203.A O no hydrogen 2.853 N/A THR 211.A OG1 ASP 202.A OD1 no hydrogen 2.697 N/A THR 211.A OG1 ASP 202.A OD2 no hydrogen 3.042 N/A GLY 219.A N GLY 216.A O no hydrogen 2.982 N/A LEU 220.A N ALA 217.A O no hydrogen 3.148 N/A LEU 222.A N GLY 219.A O no hydrogen 2.980 N/A THR 227.A N ASP 225.A OD1 no hydrogen 3.023 N/A THR 227.A OG1 ASP 225.A OD1 no hydrogen 2.666 N/A ALA 230.A N THR 227.A O no hydrogen 3.256 N/A ALA 230.A N THR 227.A OG1 no hydrogen 3.394 N/A ARG 231.A N THR 227.A O no hydrogen 3.036 N/A ARG 231.A NE PHE 226.A O no hydrogen 2.512 N/A ARG 231.A NH1 SER 4.A O no hydrogen 3.018 N/A ARG 231.A NH1 SER 5.A OG no hydrogen 2.812 N/A ARG 231.A NH1 ASN 178.A OD1 no hydrogen 3.381 N/A ARG 231.A NH2 ASN 178.A OD1 no hydrogen 2.907 N/A ARG 231.A NH2 PHE 226.A O no hydrogen 3.452 N/A PHE 232.A N PRO 228.A O no hydrogen 2.975 N/A LEU 233.A N SER 229.A O no hydrogen 3.342 N/A ARG 234.A N ALA 230.A O no hydrogen 3.062 N/A ARG 234.A NE SER 261.A O no hydrogen 2.912 N/A ARG 234.A NH1 PRO 223.A O no hydrogen 2.827 N/A ARG 234.A NH1 ASP 225.A O no hydrogen 2.715 N/A ARG 234.A NH2 ASP 225.A O no hydrogen 3.100 N/A ARG 234.A NH2 SER 261.A O no hydrogen 2.904 N/A VAL 235.A N ARG 231.A O no hydrogen 3.005 N/A ALA 236.A N PHE 232.A O no hydrogen 2.896 N/A TYR 237.A N LEU 233.A O no hydrogen 2.739 N/A TYR 237.A OH LEU 189.A O no hydrogen 2.696 N/A TRP 238.A N ARG 234.A O no hydrogen 2.753 N/A LYS 239.A N VAL 235.A O no hydrogen 2.684 N/A LYS 239.A NZ SER 8.A O no hydrogen 2.681 N/A LYS 239.A NZ ILE 173.A O no hydrogen 2.675 N/A LYS 239.A NZ GLY 174.A O no hydrogen 3.140 N/A LYS 240.A N ALA 236.A O no hydrogen 2.884 N/A TYR 241.A N TYR 237.A O no hydrogen 3.103 N/A THR 242.A N TRP 238.A O no hydrogen 2.962 N/A THR 242.A OG1 TRP 238.A O no hydrogen 2.623 N/A LYS 246.A N GLU 250.A OE1 no hydrogen 2.628 N/A GLU 250.A N ASN 247.A OD1 no hydrogen 2.900 N/A GLY 251.A N ASN 247.A O no hydrogen 2.903 N/A VAL 252.A N GLU 248.A O no hydrogen 2.980 N/A THR 253.A N THR 249.A O no hydrogen 3.008 N/A THR 253.A OG1 THR 249.A O no hydrogen 3.290 N/A ASN 254.A N GLU 250.A O no hydrogen 2.778 N/A LEU 255.A N GLY 251.A O no hydrogen 2.986 N/A PHE 256.A N VAL 252.A O no hydrogen 3.132 N/A HIS 257.A N THR 253.A O no hydrogen 2.897 N/A ILE 258.A N ASN 254.A O no hydrogen 2.908 N/A LEU 259.A N LEU 255.A O no hydrogen 2.900 N/A SER 260.A N PHE 256.A O no hydrogen 2.917 N/A SER 260.A N HIS 257.A O no hydrogen 2.967 N/A SER 260.A OG HIS 257.A O no hydrogen 2.337 N/A SER 261.A N ILE 258.A O no hydrogen 2.999 N/A SER 261.A OG ILE 258.A O no hydrogen 2.761 N/A VAL 262.A N LEU 259.A O no hydrogen 2.973 N/A ASN 263.A N SER 260.A O no hydrogen 3.420 N/A ILE 264.A N THR 279.A OG1 no hydrogen 2.758 N/A LYS 266.A N TYR 297.A OH no hydrogen 3.081 N/A VAL 268.A N PRO 265.A O no hydrogen 3.302 N/A THR 271.A N LYS 275.A O no hydrogen 2.886 N/A GLU 273.A N THR 271.A OG1 no hydrogen 3.179 N/A GLY 274.A N THR 271.A O no hydrogen 2.742 N/A LYS 275.A N THR 271.A OG1 no hydrogen 3.223 N/A ASP 277.A N VAL 269.A O no hydrogen 2.894 N/A TYR 278.A N PHE 24.A O no hydrogen 3.124 N/A TYR 278.A OH GLU 27.A OE2 no hydrogen 2.577 N/A THR 279.A N ILE 264.A O no hydrogen 3.185 N/A THR 279.A OG1 ASP 23.A OD1 no hydrogen 2.737 N/A ILE 280.A N MET 22.A O no hydrogen 2.823 N/A TYR 281.A OH ASP 72.A OD2 no hydrogen 2.626 N/A THR 282.A N LYS 295.A O no hydrogen 2.918 N/A SER 283.A N ARG 20.A O no hydrogen 2.938 N/A SER 283.A OG ASP 72.A OD2 no hydrogen 3.543 N/A SER 283.A OG TYR 292.A OH no hydrogen 2.979 N/A ALA 284.A N TYR 293.A O no hydrogen 2.807 N/A MET 285.A N PHE 18.A O no hydrogen 2.831 N/A CYS 286.A N ASN 291.A O no hydrogen 3.093 N/A CYS 286.A SG SER 16.A O no hydrogen 3.821 N/A CYS 286.A SG SER 289.A OG no hydrogen 3.562 N/A ALA 287.A N SER 16.A O no hydrogen 2.977 N/A GLN 288.A NE2 ALA 152.A O no hydrogen 2.871 N/A SER 289.A OG GLU 248.A OE2 no hydrogen 2.372 N/A LYS 290.A N CYS 286.A O no hydrogen 2.882 N/A LYS 290.A NZ GLN 288.A O no hydrogen 3.034 N/A ASN 291.A N SER 289.A OG no hydrogen 3.214 N/A ASN 291.A ND2 GLU 248.A OE2 no hydrogen 2.950 N/A ASN 291.A ND2 TYR 293.A OH no hydrogen 3.325 N/A TYR 292.A N VAL 305.A O no hydrogen 2.813 N/A TYR 292.A OH ASP 72.A OD1 no hydrogen 2.453 N/A TYR 293.A N ALA 284.A O no hydrogen 2.819 N/A TYR 293.A OH GLU 248.A OE2 no hydrogen 2.740 N/A PHE 294.A N SER 303.A O no hydrogen 3.026 N/A LYS 295.A N THR 282.A O no hydrogen 2.819 N/A LEU 296.A N ASN 299.A O no hydrogen 2.869 N/A TYR 297.A N ILE 280.A O no hydrogen 2.704 N/A ASN 299.A N LEU 296.A O no hydrogen 3.202 N/A ASN 299.A ND2 ASP 323.A O no hydrogen 3.232 N/A SER 300.A N GLN 326.A OE1 no hydrogen 2.920 N/A ARG 301.A N ASN 299.A OD1 no hydrogen 3.298 N/A ARG 301.A NH1 ASP 327.A OD2 no hydrogen 3.016 N/A SER 303.A N PHE 294.A O no hydrogen 2.956 N/A VAL 305.A N TYR 292.A O no hydrogen 2.758 N/A LEU 307.A N LYS 290.A O no hydrogen 3.250 N/A ALA 309.A N SER 306.A O no hydrogen 3.325 N/A ALA 309.A N SER 306.A OG no hydrogen 3.127 N/A GLU 310.A N LEU 307.A O no hydrogen 3.106 N/A ASN 313.A N ASN 311.A OD1 no hydrogen 2.991 N/A SER 314.A N ASN 311.A O no hydrogen 2.986 N/A SER 314.A OG ASN 311.A O no hydrogen 2.503 N/A ILE 318.A N ILE 34.A O no hydrogen 3.126 N/A PHE 320.A N VAL 32.A O no hydrogen 3.008 N/A LYS 325.A N ASP 323.A OD1 no hydrogen 3.019 N/A ASP 327.A N ASN 299.A OD1 no hydrogen 3.096 N/A