Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2izs_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 4.A N PHE 8.A O no hydrogen 2.886 N/A ASN 7.A ND2 ASN 27.A OD1 no hydrogen 2.745 N/A PHE 8.A N VAL 4.A O no hydrogen 3.136 N/A ARG 9.A N LYS 26.A O no hydrogen 2.765 N/A VAL 10.A N LEU 2.A O no hydrogen 2.940 N/A GLY 11.A N LEU 24.A O no hydrogen 2.609 N/A ILE 14.A N LEU 22.A O no hydrogen 2.954 N/A ASN 18.A ND2 ILE 14.A O no hydrogen 2.824 N/A PHE 19.A N GLY 17.A O no hydrogen 2.466 N/A ARG 23.A N ILE 36.A O no hydrogen 2.832 N/A ARG 23.A NH1 GLY 11.A O no hydrogen 2.801 N/A LEU 24.A N LYS 12.A O no hydrogen 2.766 N/A GLY 25.A N VAL 34.A O no hydrogen 2.888 N/A LYS 26.A N ARG 9.A O no hydrogen 2.929 N/A LYS 26.A NZ ASN 31.A OD1 no hydrogen 2.978 N/A ASN 27.A N GLU 32.A O no hydrogen 2.668 N/A LEU 28.A N ASN 7.A O no hydrogen 2.898 N/A TYR 29.A N ASN 27.A OD1 no hydrogen 3.001 N/A THR 30.A N ASN 27.A O no hydrogen 3.353 N/A THR 30.A N ASN 27.A OD1 no hydrogen 3.319 N/A THR 30.A OG1 GLU 32.A OE1 no hydrogen 2.982 N/A GLU 32.A N ASN 27.A O no hydrogen 3.188 N/A VAL 34.A N GLY 25.A O no hydrogen 2.826 N/A ALA 35.A N LEU 81.A O no hydrogen 2.732 N/A ILE 36.A N ARG 23.A O no hydrogen 2.846 N/A LYS 37.A N MET 79.A O no hydrogen 2.806 N/A LYS 37.A NZ GLU 51.A OE1 no hydrogen 2.586 N/A LYS 37.A NZ GLU 51.A OE2 no hydrogen 3.355 N/A LEU 38.A N GLU 21.A O no hydrogen 2.693 N/A GLU 39.A N ASN 77.A O no hydrogen 2.841 N/A MET 41.A N LYS 75.A O no hydrogen 2.795 N/A SER 43.A N PRO 40.A O no hydrogen 2.915 N/A GLN 47.A N GLU 39.A OE2 no hydrogen 2.805 N/A LEU 48.A N GLU 39.A OE2 no hydrogen 3.130 N/A GLU 51.A N GLN 47.A O no hydrogen 2.822 N/A TYR 52.A N LEU 48.A O no hydrogen 2.869 N/A ARG 53.A N HIS 49.A O no hydrogen 2.992 N/A PHE 54.A N LEU 50.A O no hydrogen 2.933 N/A TYR 55.A N GLU 51.A O no hydrogen 2.890 N/A LYS 56.A N TYR 52.A O no hydrogen 3.028 N/A GLN 57.A N ARG 53.A O no hydrogen 3.073 N/A GLN 57.A NE2 LYS 121.A O no hydrogen 2.924 N/A GLN 57.A NE2 GLU 156.A OE1 no hydrogen 2.942 N/A LEU 58.A N PHE 54.A O no hydrogen 2.889 N/A GLY 59.A N TYR 55.A O no hydrogen 2.973 N/A ILE 64.A N GLY 61.A O no hydrogen 3.146 N/A GLN 66.A N GLU 82.A OE1 no hydrogen 3.062 N/A TYR 68.A N VAL 80.A O no hydrogen 2.812 N/A TYR 68.A OH GLN 66.A OE1.B no hydrogen 2.651 N/A TYR 69.A N VAL 80.A O no hydrogen 3.269 N/A GLY 71.A N ALA 78.A O no hydrogen 2.959 N/A CYS 73.A N TYR 76.A O no hydrogen 2.681 N/A CYS 73.A SG MET 3.A O no hydrogen 3.454 N/A TYR 76.A N CYS 73.A O no hydrogen 3.039 N/A ASN 77.A N GLU 39.A O no hydrogen 2.807 N/A ALA 78.A N GLY 71.A O no hydrogen 2.787 N/A MET 79.A N LYS 37.A O no hydrogen 2.786 N/A VAL 80.A N TYR 69.A O no hydrogen 2.829 N/A LEU 81.A N ALA 35.A O no hydrogen 2.852 N/A GLU 82.A N GLN 66.A O no hydrogen 2.698 N/A GLY 85.A N ILE 135.A O no hydrogen 2.622 N/A SER 87.A N ASP 90.A OD2 no hydrogen 3.051 N/A LEU 88.A N PHE 133.A O no hydrogen 2.802 N/A GLU 89.A N PRO 130.A O no hydrogen 3.386 N/A ASP 90.A N SER 87.A OG no hydrogen 3.119 N/A LEU 91.A N SER 87.A O no hydrogen 2.916 N/A PHE 92.A N LEU 88.A O no hydrogen 2.686 N/A ASP 93.A N GLU 89.A O no hydrogen 3.010 N/A LEU 94.A N ASP 90.A O no hydrogen 3.019 N/A CYS 95.A N LEU 91.A O no hydrogen 2.993 N/A CYS 95.A N PHE 92.A O no hydrogen 3.049 N/A CYS 95.A SG LEU 91.A O no hydrogen 3.436 N/A ASP 96.A N ASP 93.A O no hydrogen 3.080 N/A ARG 97.A N PHE 92.A O no hydrogen 2.708 N/A ARG 97.A NH1 GLU 89.A OE2 no hydrogen 2.909 N/A ARG 97.A NH1 ASP 93.A OD1 no hydrogen 2.728 N/A ARG 97.A NH2 TYR 206.A OH no hydrogen 2.769 N/A THR 98.A N CYS 95.A O no hydrogen 3.518 N/A PHE 99.A N PHE 207.A O no hydrogen 2.944 N/A SER 100.A N ASP 289.A OD2 no hydrogen 2.668 N/A SER 100.A OG ASP 289.A OD1 no hydrogen 2.700 N/A SER 100.A OG ASP 289.A OD2 no hydrogen 3.390 N/A LYS 102.A NZ ASP 285.A OD1 no hydrogen 2.899 N/A LYS 102.A NZ ASP 285.A OD2 no hydrogen 3.311 N/A THR 103.A N SER 100.A OG no hydrogen 3.074 N/A VAL 104.A N SER 100.A O no hydrogen 2.820 N/A LEU 105.A N LEU 101.A O no hydrogen 2.783 N/A MET 106.A N LYS 102.A O no hydrogen 2.985 N/A ILE 107.A N THR 103.A O no hydrogen 2.985 N/A ALA 108.A N VAL 104.A O no hydrogen 2.736 N/A ILE 109.A N LEU 105.A O no hydrogen 2.866 N/A GLN 110.A N MET 106.A O no hydrogen 3.399 N/A GLN 110.A NE2 MET 106.A O no hydrogen 2.785 N/A GLN 110.A NE2 TYR 288.A OH no hydrogen 2.737 N/A LEU 111.A N ILE 107.A O no hydrogen 2.858 N/A ILE 112.A N ALA 108.A O no hydrogen 2.875 N/A SER 113.A N ILE 109.A O no hydrogen 3.404 N/A SER 113.A OG ILE 109.A O no hydrogen 3.459 N/A ARG 114.A N GLN 110.A O no hydrogen 2.707 N/A ARG 114.A NE ILE 146.A O no hydrogen 2.834 N/A ARG 114.A NH2 ILE 146.A O no hydrogen 2.816 N/A MET 115.A N LEU 111.A O no hydrogen 2.798 N/A GLU 116.A N ILE 112.A O no hydrogen 2.821 N/A TYR 117.A N SER 113.A O no hydrogen 2.922 N/A TYR 117.A OH LEU 58.A O no hydrogen 2.608 N/A VAL 118.A N ARG 114.A O no hydrogen 3.127 N/A HIS 119.A N MET 115.A O no hydrogen 2.905 N/A HIS 119.A ND1 TYR 266.A OH no hydrogen 2.697 N/A HIS 119.A NE2 ASP 196.A OD2 no hydrogen 2.591 N/A SER 120.A N GLU 116.A O no hydrogen 2.769 N/A SER 120.A OG TYR 117.A O no hydrogen 2.562 N/A LYS 121.A N TYR 117.A O no hydrogen 3.218 N/A LYS 121.A N VAL 118.A O no hydrogen 3.021 N/A ASN 122.A N HIS 119.A O no hydrogen 3.037 N/A LEU 123.A N VAL 118.A O no hydrogen 3.213 N/A ILE 124.A N LYS 155.A O no hydrogen 2.735 N/A TYR 125.A N ASP 196.A OD1 no hydrogen 3.317 N/A TYR 125.A N ASP 196.A OD2 no hydrogen 2.913 N/A TYR 125.A OH ILE 149.A O no hydrogen 2.498 N/A TYR 125.A OH ASP 150.A O no hydrogen 3.308 N/A ARG 126.A N ASP 196.A OD1 no hydrogen 2.766 N/A ARG 126.A NE LEU 153.A O no hydrogen 2.852 N/A ARG 126.A NH1 LEU 153.A O no hydrogen 2.844 N/A LYS 129.A NZ THR 177.A OG1.A no hydrogen 3.209 N/A LYS 129.A NZ THR 177.A OG1.B no hydrogen 3.283 N/A GLU 131.A N GLU 131.A OE1 no hydrogen 2.829 N/A ASN 132.A N LYS 129.A O no hydrogen 3.087 N/A ASN 132.A ND2 ASP 127.A O no hydrogen 2.985 N/A ASN 132.A ND2 ASP 127.A OD2 no hydrogen 2.966 N/A PHE 133.A N PRO 130.A O no hydrogen 3.332 N/A LEU 134.A N HIS 147.A O no hydrogen 2.905 N/A ILE 135.A N PRO 86.A O no hydrogen 2.986 N/A GLY 136.A N THR 142.A O no hydrogen 3.274 N/A ASN 140.A N ARG 137.A O no hydrogen 2.998 N/A LYS 141.A N PRO 138.A O no hydrogen 2.932 N/A GLN 144.A N GLN 144.A OE1 no hydrogen 2.995 N/A GLN 144.A NE2 LYS 141.A O no hydrogen 3.344 N/A VAL 145.A N THR 142.A O no hydrogen 2.913 N/A ILE 146.A N GLN 110.A OE1 no hydrogen 3.079 N/A HIS 147.A N LEU 134.A O no hydrogen 2.663 N/A ILE 148.A N GLY 63.A O no hydrogen 2.814 N/A ILE 149.A N ASN 132.A O no hydrogen 2.828 N/A PHE 151.A N GLU 51.A OE2 no hydrogen 2.882 N/A ALA 154.A N PHE 151.A O no hydrogen 3.169 N/A LYS 155.A N ILE 124.A O no hydrogen 2.971 N/A TYR 157.A N ASN 122.A O no hydrogen 2.982 N/A TYR 157.A OH HIS 119.A O no hydrogen 2.603 N/A ASP 159.A N LYS 164.A O no hydrogen 2.828 N/A GLU 161.A N ASP 159.A OD2 no hydrogen 3.172 N/A THR 162.A N ASP 159.A OD2 no hydrogen 3.218 N/A LYS 163.A N ASP 159.A O no hydrogen 2.673 N/A LYS 164.A N THR 162.A OG1 no hydrogen 3.174 N/A HIS 165.A ND1 ILE 166.A O no hydrogen 2.850 N/A ILE 166.A N TYR 157.A O no hydrogen 2.585 N/A TYR 168.A OH GLU 170.A OE2 no hydrogen 2.657 N/A ARG 169.A NE GLU 170.A O no hydrogen 3.064 N/A ARG 169.A NH2 GLU 170.A O no hydrogen 3.043 N/A LYS 172.A N GLY 188.A O no hydrogen 2.858 N/A THR 175.A OG1.A LEU 174.A O.B no hydrogen 2.431 N/A GLY 176.A N.A LEU 174.A O.B no hydrogen 2.971 N/A ARG 179.A NH1 TYR 180.A OH no hydrogen 3.114 N/A TYR 180.A N THR 177.A O.B no hydrogen 3.277 N/A MET 181.A N THR 177.A O.B no hydrogen 3.331 N/A SER 182.A OG THR 185.A OG1 no hydrogen 2.663 N/A SER 182.A OG ASP 195.A OD1 no hydrogen 2.445 N/A ILE 183.A N GLU 198.A OE2 no hydrogen 2.950 N/A THR 185.A N SER 182.A OG no hydrogen 3.010 N/A THR 185.A OG1 SER 182.A OG no hydrogen 2.663 N/A HIS 186.A N SER 182.A O no hydrogen 3.176 N/A LEU 187.A N ILE 183.A O no hydrogen 3.184 N/A GLY 188.A N THR 185.A O no hydrogen 2.820 N/A LYS 189.A N ASN 184.A O no hydrogen 3.171 N/A LYS 189.A NZ ASN 184.A OD1 no hydrogen 2.777 N/A GLU 190.A N ARG 169.A O no hydrogen 2.726 N/A SER 192.A N ASP 195.A OD2 no hydrogen 2.847 N/A SER 192.A OG PHE 260.A O no hydrogen 2.831 N/A ARG 193.A NH2 PHE 261.A O no hydrogen 2.926 N/A ARG 194.A NH1 LEU 258.A O no hydrogen 2.860 N/A ASP 195.A N SER 192.A O no hydrogen 3.053 N/A LEU 197.A N ARG 193.A O no hydrogen 3.389 N/A GLU 198.A N ARG 194.A O no hydrogen 2.803 N/A ALA 199.A N ASP 195.A O no hydrogen 2.913 N/A LEU 200.A N ASP 196.A O no hydrogen 3.042 N/A GLY 201.A N LEU 197.A O no hydrogen 2.976 N/A HIS 202.A N GLU 198.A O no hydrogen 2.995 N/A HIS 202.A ND1 TYR 180.A O no hydrogen 2.669 N/A MET 203.A N ALA 199.A O no hydrogen 3.006 N/A PHE 204.A N LEU 200.A O no hydrogen 2.776 N/A MET 205.A N GLY 201.A O no hydrogen 2.981 N/A TYR 206.A N HIS 202.A O no hydrogen 2.891 N/A TYR 206.A OH GLU 89.A OE1 no hydrogen 2.678 N/A PHE 207.A N MET 203.A O no hydrogen 2.939 N/A LEU 208.A N PHE 204.A O no hydrogen 2.976 N/A ARG 209.A N MET 205.A O no hydrogen 2.826 N/A ARG 209.A NE SER 211.A O no hydrogen 2.999 N/A ARG 209.A NH1 LEU 241.A O no hydrogen 3.104 N/A GLY 210.A N TYR 206.A O no hydrogen 2.769 N/A LEU 212.A N GLN 215.A OE1 no hydrogen 2.744 N/A TRP 214.A NE1 ARG 179.A O no hydrogen 2.786 N/A GLN 215.A N LEU 212.A O no hydrogen 3.108 N/A LEU 217.A N TRP 214.A O no hydrogen 3.505 N/A GLU 224.A N THR 221.A OG1 no hydrogen 2.989 N/A ARG 225.A N THR 221.A O no hydrogen 3.039 N/A ARG 225.A NE LEU 217.A O no hydrogen 2.872 N/A TYR 226.A N LEU 222.A O no hydrogen 2.801 N/A TYR 226.A OH GLY 176.A O.A no hydrogen 2.782 N/A GLN 227.A N LYS 223.A O no hydrogen 2.885 N/A GLN 227.A NE2 ASP 231.A OD1 no hydrogen 2.840 N/A LYS 228.A N GLU 224.A O no hydrogen 2.794 N/A LYS 228.A NZ LYS 218.A O no hydrogen 2.839 N/A ILE 229.A N ARG 225.A O no hydrogen 2.964 N/A GLY 230.A N TYR 226.A O no hydrogen 2.934 N/A ASP 231.A N GLN 227.A O no hydrogen 2.828 N/A THR 232.A N LYS 228.A O no hydrogen 2.846 N/A THR 232.A OG1 LYS 228.A O no hydrogen 3.264 N/A LYS 233.A N ILE 229.A O no hydrogen 2.917 N/A LYS 233.A NZ ALA 178.A O no hydrogen 2.453 N/A LYS 233.A NZ MET 181.A O no hydrogen 2.694 N/A LYS 233.A NZ HIS 186.A NE2 no hydrogen 2.793 N/A ARG 234.A N GLY 230.A O no hydrogen 2.826 N/A ARG 234.A NH2 ASP 231.A OD1 no hydrogen 3.034 N/A ALA 235.A N ASP 231.A O no hydrogen 2.799 N/A THR 236.A N LYS 233.A O no hydrogen 3.382 N/A THR 236.A OG1 THR 232.A O no hydrogen 2.605 N/A VAL 240.A N PRO 237.A O no hydrogen 2.959 N/A LEU 241.A N PRO 237.A O no hydrogen 2.938 N/A CYS 242.A N ILE 238.A O no hydrogen 2.743 N/A GLU 243.A N VAL 240.A O no hydrogen 3.240 N/A PHE 245.A N CYS 242.A O no hydrogen 2.864 N/A ALA 249.A N PHE 245.A O no hydrogen 3.029 N/A THR 250.A N PRO 246.A O no hydrogen 2.830 N/A THR 250.A OG1 PRO 246.A O no hydrogen 3.117 N/A TYR 251.A N GLU 247.A O no hydrogen 2.747 N/A TYR 251.A OH LEU 197.A O no hydrogen 2.566 N/A LEU 252.A N MET 248.A O no hydrogen 2.796 N/A ARG 253.A N ALA 249.A O no hydrogen 2.842 N/A ARG 253.A NH2.B GLU 239.A OE2 no hydrogen 3.029 N/A TYR 254.A N THR 250.A O no hydrogen 2.969 N/A VAL 255.A N TYR 251.A O no hydrogen 3.007 N/A ARG 256.A N LEU 252.A O no hydrogen 2.940 N/A ARG 256.A NE GLU 198.A OE2 no hydrogen 2.818 N/A ARG 256.A NH2 HIS 202.A NE2 no hydrogen 2.938 N/A ARG 257.A N ARG 253.A O no hydrogen 3.074 N/A ARG 257.A N TYR 254.A O no hydrogen 3.190 N/A LEU 258.A N VAL 255.A O no hydrogen 3.340 N/A ASP 259.A N GLU 262.A OE1 no hydrogen 2.891 N/A PHE 261.A N ASP 259.A OD2 no hydrogen 2.992 N/A GLU 262.A N ASP 259.A O no hydrogen 3.233 N/A ASP 265.A N TYR 254.A OH no hydrogen 2.854 N/A TYR 266.A OH HIS 119.A ND1 no hydrogen 2.697 N/A TYR 268.A N ASP 265.A OD1 no hydrogen 2.972 N/A LEU 269.A N ASP 265.A O no hydrogen 3.072 N/A ARG 270.A N TYR 266.A O no hydrogen 2.918 N/A ARG 270.A NH1 GLU 116.A OE1 no hydrogen 2.917 N/A ARG 270.A NH2 GLU 116.A OE1 no hydrogen 2.925 N/A ARG 270.A NH2 ASP 267.A OD1 no hydrogen 3.041 N/A LYS 271.A N ASP 267.A O no hydrogen 2.926 N/A LYS 271.A NZ ASP 275.A OD2 no hydrogen 2.929 N/A LEU 272.A N TYR 268.A O no hydrogen 2.961 N/A PHE 273.A N LEU 269.A O no hydrogen 3.394 N/A THR 274.A N ARG 270.A O no hydrogen 2.707 N/A THR 274.A OG1 ARG 270.A O no hydrogen 3.306 N/A THR 274.A OG1 LYS 271.A O no hydrogen 3.524 N/A ASP 275.A N LYS 271.A O no hydrogen 2.733 N/A LEU 276.A N LEU 272.A O no hydrogen 3.157 N/A PHE 277.A N PHE 273.A O no hydrogen 2.780 N/A ASP 278.A N THR 274.A O no hydrogen 2.987 N/A ARG 279.A N ASP 275.A O no hydrogen 2.887 N/A LYS 280.A N LEU 276.A O no hydrogen 2.917 N/A GLY 281.A N ASP 278.A O no hydrogen 3.050 N/A TYR 282.A N PHE 277.A O no hydrogen 3.097 N/A GLU 287.A N ASP 285.A OD1 no hydrogen 2.882 N/A TYR 288.A OH GLN 144.A O no hydrogen 2.592 N/A ASP 289.A N THR 103.A OG1 no hydrogen 2.728 N/A ILE 291.A N TYR 288.A O no hydrogen 2.915 N/A LYS 293.A N TRP 290.A O no hydrogen 2.975 N/A LYS 293.A NZ ASP 289.A O no hydrogen 2.724 N/A