Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2j8f_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 1.A N ASP 189.A OD2 no hydrogen 2.825 N/A LYS 2.A N ASP 5.A OD2 no hydrogen 2.904 N/A LYS 3.A N ASP 188.A OD1 no hydrogen 2.858 N/A ASN 4.A N VAL 185.A O no hydrogen 2.664 N/A ASN 4.A ND2 ALA 338.A O no hydrogen 2.957 N/A ASP 5.A N LYS 2.A O no hydrogen 2.985 N/A PHE 7.A N ASN 183.A O no hydrogen 3.093 N/A VAL 8.A N ASN 29.A O no hydrogen 3.115 N/A ASP 9.A N ASP 181.A O no hydrogen 3.463 N/A VAL 10.A N ILE 31.A O no hydrogen 3.010 N/A SER 11.A N ASN 14.A OD1 no hydrogen 2.897 N/A HIS 13.A N SER 11.A OG no hydrogen 3.193 N/A ASN 14.A N SER 11.A O no hydrogen 2.925 N/A GLY 15.A N SER 12.A O no hydrogen 3.036 N/A ILE 18.A N GLN 51.A OE1 no hydrogen 2.844 N/A THR 19.A N ASP 17.A OD1 no hydrogen 3.178 N/A THR 19.A OG1 ASP 17.A OD1 no hydrogen 2.605 N/A LEU 22.A N ILE 18.A O no hydrogen 3.179 N/A GLU 23.A N THR 19.A O no hydrogen 2.986 N/A GLN 24.A N GLY 20.A O no hydrogen 3.093 N/A GLN 24.A NE2 GLY 20.A O no hydrogen 3.221 N/A MET 25.A N ILE 21.A O no hydrogen 2.965 N/A GLY 26.A N LEU 22.A O no hydrogen 2.910 N/A THR 27.A N LEU 22.A O no hydrogen 3.254 N/A THR 27.A OG1 LEU 6.A O no hydrogen 3.466 N/A ASN 29.A N THR 27.A OG1 no hydrogen 3.062 N/A ASN 29.A ND2 LEU 6.A O no hydrogen 2.968 N/A THR 30.A N ASN 53.A O no hydrogen 3.316 N/A THR 30.A OG1 SER 52.A OG no hydrogen 2.801 N/A ILE 31.A N VAL 8.A O no hydrogen 2.935 N/A ILE 32.A N GLY 56.A O no hydrogen 3.259 N/A LYS 33.A N VAL 10.A O no hydrogen 2.857 N/A LYS 33.A NZ GLU 36.A OE2 no hydrogen 2.786 N/A ILE 34.A N TYR 58.A O no hydrogen 2.911 N/A SER 35.A OG HIS 59.A ND1 no hydrogen 2.722 N/A GLU 36.A N TYR 40.A O no hydrogen 3.039 N/A SER 37.A N PHE 60.A O no hydrogen 3.358 N/A TYR 40.A N GLU 36.A O no hydrogen 3.208 N/A ASN 42.A N ILE 34.A O no hydrogen 2.891 N/A ASN 42.A ND2 LYS 33.A O no hydrogen 2.863 N/A ASN 42.A ND2 GLN 48.A OE1 no hydrogen 3.073 N/A CYS 44.A N ASN 42.A OD1 no hydrogen 2.938 N/A LEU 45.A N ASN 42.A O no hydrogen 3.217 N/A GLN 48.A N CYS 44.A O no hydrogen 2.885 N/A GLN 48.A NE2 SER 11.A O no hydrogen 2.925 N/A GLN 48.A NE2 GLY 15.A O no hydrogen 2.984 N/A VAL 49.A N LEU 45.A O no hydrogen 2.933 N/A GLU 50.A N SER 46.A O no hydrogen 3.021 N/A GLN 51.A N ALA 47.A O no hydrogen 3.065 N/A GLN 51.A NE2 TYR 16.A O no hydrogen 2.748 N/A SER 52.A N VAL 49.A O no hydrogen 3.147 N/A SER 52.A OG THR 30.A OG1 no hydrogen 2.801 N/A SER 52.A OG GLN 48.A O no hydrogen 2.737 N/A ASN 53.A N THR 28.A O no hydrogen 2.833 N/A ILE 55.A N THR 30.A O no hydrogen 2.756 N/A PHE 57.A N TYR 87.A O no hydrogen 3.275 N/A TYR 58.A N ILE 32.A O no hydrogen 2.988 N/A HIS 59.A N VAL 89.A O no hydrogen 2.942 N/A HIS 59.A ND1 SER 35.A OG no hydrogen 2.722 N/A HIS 59.A NE2 GLU 73.A OE1 no hydrogen 2.642 N/A PHE 60.A N SER 35.A O no hydrogen 2.905 N/A ALA 61.A N ASP 91.A O no hydrogen 2.979 N/A ARG 62.A N GLU 73.A OE1 no hydrogen 3.061 N/A ARG 62.A N GLU 73.A OE2 no hydrogen 3.220 N/A ARG 62.A NE GLU 36.A OE1 no hydrogen 2.995 N/A ARG 62.A NH1 ASP 94.A OD2 no hydrogen 2.885 N/A ARG 62.A NH1 ASP 95.A OD2 no hydrogen 2.908 N/A ARG 62.A NH2 GLU 36.A OE1 no hydrogen 2.932 N/A ASP 66.A N PHE 63.A O no hydrogen 2.990 N/A GLU 69.A N ASP 66.A OD1 no hydrogen 3.085 N/A ALA 70.A N ASP 66.A O no hydrogen 3.007 N/A GLU 71.A N VAL 67.A O no hydrogen 3.019 N/A ARG 72.A N ALA 68.A O no hydrogen 3.148 N/A ARG 72.A NH2 GLU 69.A OE1 no hydrogen 2.965 N/A GLU 73.A N GLU 69.A O no hydrogen 2.926 N/A ALA 74.A N ALA 70.A O no hydrogen 2.909 N/A GLN 75.A N GLU 71.A O no hydrogen 3.064 N/A PHE 76.A N ARG 72.A O no hydrogen 3.086 N/A PHE 77.A N GLU 73.A O no hydrogen 3.006 N/A LEU 78.A N ALA 74.A O no hydrogen 2.939 N/A ASP 79.A N GLN 75.A O no hydrogen 2.842 N/A ASN 80.A N PHE 77.A O no hydrogen 3.012 N/A ASN 80.A ND2 PHE 76.A O no hydrogen 2.831 N/A VAL 81.A N LEU 78.A O no hydrogen 3.400 N/A LYS 86.A NZ ASP 189.A OD2 no hydrogen 3.089 N/A TYR 87.A OH ASP 189.A OD1 no hydrogen 2.438 N/A LEU 88.A N LYS 120.A O no hydrogen 3.065 N/A VAL 89.A N PHE 57.A O no hydrogen 2.854 N/A LEU 90.A N ILE 122.A O no hydrogen 2.747 N/A ASP 91.A N HIS 59.A O no hydrogen 2.924 N/A TYR 92.A N TYR 124.A O no hydrogen 2.905 N/A TYR 92.A OH GLY 64.A O no hydrogen 2.749 N/A ASP 99.A N SER 97.A OG no hydrogen 3.112 N/A GLN 101.A NE2 ASN 105.A OD1 no hydrogen 3.035 N/A GLN 101.A NE2 GLN 138.A OE1 no hydrogen 2.908 N/A ALA 102.A N ASP 99.A OD1 no hydrogen 3.052 N/A ASN 103.A N ASP 99.A O no hydrogen 3.067 N/A THR 104.A N ALA 100.A O no hydrogen 2.966 N/A THR 104.A OG1 ALA 100.A O no hydrogen 2.804 N/A ASN 105.A N GLN 101.A O no hydrogen 2.840 N/A ALA 106.A N ALA 102.A O no hydrogen 2.917 N/A CYS 107.A N ASN 103.A O no hydrogen 2.956 N/A CYS 107.A SG ASN 103.A O no hydrogen 3.412 N/A LEU 108.A N THR 104.A O no hydrogen 2.704 N/A ARG 109.A N ASN 105.A O no hydrogen 2.949 N/A ARG 109.A NE GLU 71.A OE2 no hydrogen 2.918 N/A ARG 109.A NH2 GLU 71.A OE2 no hydrogen 3.542 N/A PHE 110.A N ALA 106.A O no hydrogen 2.984 N/A MET 111.A N CYS 107.A O no hydrogen 2.948 N/A GLN 112.A N LEU 108.A O no hydrogen 2.928 N/A GLN 112.A NE2 GLN 112.A O no hydrogen 3.333 N/A GLN 112.A NE2 ASP 116.A OD1 no hydrogen 2.832 N/A MET 113.A N ARG 109.A O no hydrogen 3.077 N/A ILE 114.A N PHE 110.A O no hydrogen 3.157 N/A ALA 115.A N MET 111.A O no hydrogen 2.926 N/A ASP 116.A N GLN 112.A O no hydrogen 2.876 N/A ALA 117.A N MET 113.A O no hydrogen 3.224 N/A ALA 117.A N ILE 114.A O no hydrogen 3.286 N/A GLY 118.A N ALA 115.A O no hydrogen 2.991 N/A TYR 119.A N ILE 114.A O no hydrogen 3.279 N/A LYS 120.A N LYS 86.A O no hydrogen 2.858 N/A LYS 120.A NZ GLU 190.A O no hydrogen 3.264 N/A ILE 122.A N LEU 88.A O no hydrogen 3.055 N/A TYR 123.A N SER 146.A O no hydrogen 2.900 N/A TYR 123.A OH THR 130.A OG1 no hydrogen 3.036 N/A TYR 124.A N LEU 90.A O no hydrogen 2.792 N/A TYR 124.A OH GLN 174.A OE1 no hydrogen 2.606 N/A SER 125.A N TRP 148.A O no hydrogen 3.213 N/A SER 125.A OG TYR 92.A O no hydrogen 2.820 N/A SER 125.A OG TYR 126.A O no hydrogen 3.448 N/A SER 125.A OG THR 130.A OG1 no hydrogen 3.400 N/A LYS 127.A NZ SER 166.A O no hydrogen 2.980 N/A THR 130.A N TYR 126.A O no hydrogen 3.057 N/A THR 130.A OG1 TYR 123.A OH no hydrogen 3.036 N/A THR 130.A OG1 TYR 126.A O no hydrogen 3.004 N/A HIS 131.A N LYS 127.A O no hydrogen 2.885 N/A ASP 132.A N PRO 128.A O no hydrogen 2.989 N/A ASN 133.A N PHE 129.A O no hydrogen 3.077 N/A ASN 133.A N THR 130.A O no hydrogen 3.373 N/A ASN 133.A ND2 PHE 129.A O no hydrogen 3.008 N/A VAL 134.A N THR 130.A O no hydrogen 3.054 N/A ASP 135.A N THR 104.A OG1 no hydrogen 2.920 N/A GLN 137.A N ASP 135.A OD1 no hydrogen 3.216 N/A GLN 137.A NE2 ASP 168.A OD2 no hydrogen 2.920 N/A GLN 138.A N ASP 135.A O no hydrogen 2.904 N/A GLN 138.A NE2 GLN 101.A OE1 no hydrogen 2.960 N/A GLN 138.A NE2 ASP 135.A OD2 no hydrogen 2.890 N/A LEU 140.A N TYR 136.A O no hydrogen 2.865 N/A ALA 141.A N GLN 137.A O no hydrogen 2.933 N/A GLN 142.A N GLN 138.A O no hydrogen 3.333 N/A GLN 142.A N ILE 139.A O no hydrogen 3.229 N/A PHE 143.A N ILE 139.A O no hydrogen 2.706 N/A SER 146.A OG PHE 143.A O no hydrogen 2.715 N/A LEU 147.A N GLY 169.A O no hydrogen 3.108 N/A TRP 148.A N TYR 123.A O no hydrogen 2.814 N/A TRP 148.A NE1 ASN 183.A OD1 no hydrogen 2.727 N/A ILE 149.A N TRP 172.A O no hydrogen 3.066 N/A ALA 150.A N SER 125.A O no hydrogen 2.982 N/A GLY 151.A N GLN 174.A O no hydrogen 3.026 N/A TYR 152.A OH GLN 174.A OE1 no hydrogen 2.569 N/A ASN 155.A N TYR 152.A O no hydrogen 2.847 N/A THR 158.A N ASP 156.A OD1 no hydrogen 2.968 N/A THR 158.A OG1 ASP 156.A OD1 no hydrogen 2.846 N/A ASN 160.A ND2 ASP 156.A OD1 no hydrogen 3.268 N/A ASN 160.A ND2 ASP 156.A OD2 no hydrogen 3.297 N/A TYR 163.A N ASN 160.A O no hydrogen 3.005 N/A PHE 164.A N PHE 161.A O no hydrogen 3.009 N/A ASP 168.A N TYR 136.A OH no hydrogen 3.121 N/A ARG 171.A N LEU 147.A O no hydrogen 2.754 N/A ARG 171.A NE ASN 145.A O no hydrogen 2.913 N/A ARG 171.A NH1 ASP 188.A O no hydrogen 2.976 N/A ARG 171.A NH2 ASN 145.A O no hydrogen 3.487 N/A TRP 172.A N LEU 147.A O no hydrogen 3.340 N/A TRP 173.A N ILE 184.A O no hydrogen 3.064 N/A TRP 173.A NE1 GLY 151.A O no hydrogen 2.908 N/A GLN 174.A N ILE 149.A O no hydrogen 2.914 N/A GLN 174.A NE2 ASP 9.A OD1 no hydrogen 2.820 N/A TYR 175.A N LYS 182.A O no hydrogen 2.851 N/A SER 176.A OG ASN 178.A O no hydrogen 3.553 N/A SER 177.A OG ASN 155.A OD1 no hydrogen 2.984 N/A ASN 178.A N SER 176.A OG no hydrogen 2.991 N/A ASN 178.A ND2 ASN 155.A O no hydrogen 3.097 N/A LYS 182.A N SER 176.A O no hydrogen 2.833 N/A LYS 182.A NZ GLY 157.A O no hydrogen 2.962 N/A LYS 182.A NZ ASN 178.A O no hydrogen 3.065 N/A ASN 183.A N PHE 7.A O no hydrogen 3.012 N/A ASN 183.A ND2 PHE 7.A O no hydrogen 3.076 N/A ASN 183.A ND2 ASP 9.A OD1 no hydrogen 2.861 N/A ILE 184.A N TRP 173.A O no hydrogen 2.904 N/A VAL 185.A N ASP 5.A O no hydrogen 2.865 N/A LEU 186.A N ARG 171.A O no hydrogen 2.807 N/A ASP 189.A N VAL 1.A O no hydrogen 3.114 N/A GLY 199.A N THR 197.A O no hydrogen 2.899 N/A THR 200.A N ARG 211.A O no hydrogen 2.876 N/A LYS 202.A N TRP 209.A O no hydrogen 2.884 N/A ASP 204.A N GLY 207.A O no hydrogen 2.919 N/A LYS 206.A N ASP 204.A OD1 no hydrogen 2.883 N/A GLY 207.A N ASP 204.A OD1 no hydrogen 3.183 N/A TRP 209.A N LYS 202.A O no hydrogen 2.868 N/A ARG 211.A N THR 200.A O no hydrogen 2.936 N/A ARG 212.A N SER 216.A O no hydrogen 2.854 N/A ARG 212.A NE GLU 223.A OE2 no hydrogen 3.019 N/A ARG 212.A NH1 SER 216.A OG no hydrogen 2.821 N/A ARG 212.A NH2 GLU 223.A OE1 no hydrogen 2.820 N/A ASN 213.A N ALA 198.A O no hydrogen 3.177 N/A GLY 215.A N ARG 212.A O no hydrogen 2.717 N/A SER 216.A N ASN 214.A OD1 no hydrogen 3.003 N/A SER 216.A OG ASN 214.A OD1 no hydrogen 2.577 N/A ASN 220.A N ASP 233.A O no hydrogen 3.011 N/A LYS 221.A N PHE 232.A O no hydrogen 3.160 N/A LYS 221.A NZ TRP 222.A O no hydrogen 2.773 N/A LYS 221.A NZ GLU 223.A OE1 no hydrogen 2.881 N/A TRP 222.A NE1 ASP 246.A OD2 no hydrogen 2.727 N/A GLU 223.A N TYR 230.A O no hydrogen 2.938 N/A ILE 225.A N VAL 228.A O no hydrogen 2.876 N/A GLY 226.A N LYS 196.A O no hydrogen 3.230 N/A VAL 228.A N ILE 225.A O no hydrogen 3.300 N/A TYR 230.A N GLU 223.A O no hydrogen 2.949 N/A PHE 232.A N LYS 221.A O no hydrogen 2.938 N/A ASP 233.A N TYR 237.A O no hydrogen 2.836 N/A LYS 235.A N ASP 233.A OD1 no hydrogen 2.902 N/A GLY 236.A N ASP 233.A O no hydrogen 2.934 N/A TYR 237.A N ASP 233.A OD1 no hydrogen 3.083 N/A TYR 237.A OH ASP 204.A OD1 no hydrogen 3.311 N/A TYR 237.A OH ASP 204.A OD2 no hydrogen 2.427 N/A CYS 238.A N TRP 208.A O no hydrogen 3.040 N/A CYS 238.A SG TRP 208.A O no hydrogen 3.995 N/A LEU 239.A N TYR 231.A O no hydrogen 2.882 N/A SER 241.A N LYS 254.A O no hydrogen 3.117 N/A GLU 242.A N LEU 253.A O no hydrogen 3.118 N/A LEU 244.A N TYR 251.A O no hydrogen 2.847 N/A ASP 246.A N LYS 249.A O no hydrogen 2.871 N/A LYS 249.A N ASP 246.A O no hydrogen 3.185 N/A TYR 251.A N LEU 244.A O no hydrogen 2.712 N/A LEU 253.A N GLU 242.A O no hydrogen 2.936 N/A LYS 254.A N ALA 258.A O no hydrogen 2.861 N/A GLY 257.A N LYS 254.A O no hydrogen 2.862 N/A ALA 258.A N ASN 256.A OD1 no hydrogen 3.092 N/A MET 259.A N TRP 229.A O no hydrogen 2.994 N/A ALA 260.A N TYR 252.A O no hydrogen 2.855 N/A GLY 262.A N MET 273.A O no hydrogen 2.823 N/A TRP 263.A NE1 THR 336.A OG1 no hydrogen 2.818 N/A VAL 264.A N TYR 271.A O no hydrogen 2.812 N/A VAL 266.A N GLU 269.A O no hydrogen 2.796 N/A GLU 269.A N VAL 266.A O no hydrogen 3.086 N/A TYR 271.A N VAL 264.A O no hydrogen 2.949 N/A TYR 271.A OH GLU 269.A OE1 no hydrogen 2.970 N/A MET 273.A N GLY 262.A O no hydrogen 2.943 N/A ASP 274.A N ALA 278.A O no hydrogen 2.771 N/A SER 276.A N ASP 274.A OD1 no hydrogen 2.855 N/A GLY 277.A N ASP 274.A O no hydrogen 2.940 N/A ALA 278.A N ASP 274.A OD1 no hydrogen 3.040 N/A MET 279.A N TRP 250.A O no hydrogen 2.904 N/A VAL 280.A N TYR 272.A O no hydrogen 2.817 N/A GLY 282.A N MET 293.A O no hydrogen 2.787 N/A VAL 284.A N TYR 291.A O no hydrogen 2.889 N/A LYS 285.A N LEU 334.A O no hydrogen 2.700 N/A LYS 285.A NZ GLU 330.A OE1 no hydrogen 2.680 N/A TYR 286.A N ASN 289.A O no hydrogen 2.816 N/A LYS 287.A N THR 336.A O no hydrogen 3.090 N/A LYS 287.A NZ VAL 337.A O no hydrogen 2.813 N/A ASN 289.A N TYR 286.A O no hydrogen 3.109 N/A TRP 290.A N PHE 305.A O no hydrogen 3.021 N/A TRP 290.A NE1 GLU 330.A OE1 no hydrogen 2.816 N/A TYR 291.A N VAL 284.A O no hydrogen 2.967 N/A TYR 291.A OH GLU 304.A OE2 no hydrogen 2.520 N/A TYR 292.A N ASN 303.A O no hydrogen 3.011 N/A MET 293.A N GLY 282.A O no hydrogen 2.985 N/A THR 294.A N VAL 301.A O no hydrogen 3.044 N/A GLY 298.A N ASN 295.A O no hydrogen 2.989 N/A ASN 299.A N GLU 296.A O no hydrogen 3.030 N/A VAL 301.A N THR 294.A O no hydrogen 2.951 N/A SER 302.A OG TRP 270.A O no hydrogen 2.698 N/A ASN 303.A N TYR 292.A O no hydrogen 2.889 N/A ASN 303.A ND2 TYR 292.A O no hydrogen 2.832 N/A PHE 305.A N TRP 290.A O no hydrogen 2.905 N/A ILE 306.A N TYR 313.A O no hydrogen 2.761 N/A LYS 307.A N ASN 289.A OD1 no hydrogen 2.969 N/A LYS 307.A NZ GLU 162.A OE1 no hydrogen 3.337 N/A LYS 307.A NZ GLY 309.A O no hydrogen 2.694 N/A SER 308.A N GLY 311.A O no hydrogen 2.826 N/A GLY 311.A N SER 308.A O no hydrogen 3.494 N/A TRP 312.A N PHE 327.A O no hydrogen 2.840 N/A TRP 312.A NE1 ASN 288.A O no hydrogen 2.834 N/A TYR 313.A N ILE 306.A O no hydrogen 2.812 N/A MET 315.A N GLU 304.A O no hydrogen 2.868 N/A ASN 316.A N GLU 320.A O no hydrogen 3.209 N/A ASN 318.A N ASN 316.A OD1 no hydrogen 3.088 N/A ALA 322.A N PHE 314.A O no hydrogen 2.918 N/A SER 326.A N TRP 312.A O no hydrogen 2.732 N/A PHE 327.A N TRP 312.A O no hydrogen 3.382 N/A LEU 334.A N TRP 283.A O no hydrogen 3.007 N/A THR 336.A N LYS 285.A O no hydrogen 2.888 N/A THR 336.A OG1 LYS 285.A O no hydrogen 2.552 N/A VAL 337.A N ASN 4.A OD1 no hydrogen 2.851 N/A