Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2nx3_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 3.A N ASP 215.A O no hydrogen 3.160 N/A VAL 4.A N GLU 35.A O no hydrogen 2.909 N/A ILE 5.A N VAL 217.A O no hydrogen 2.894 N/A ALA 6.A N VAL 37.A O no hydrogen 2.941 N/A ILE 11.A N SER 41.A O no hydrogen 2.972 N/A GLU 12.A N ALA 10.A O no hydrogen 2.964 N/A GLU 14.A N TYR 60.A OH no hydrogen 3.081 N/A LEU 16.A N SER 13.A OG no hydrogen 3.003 N/A LEU 17.A N SER 13.A O no hydrogen 3.436 N/A LEU 18.A N GLU 14.A O no hydrogen 3.203 N/A LYS 19.A N GLU 15.A O no hydrogen 3.187 N/A VAL 20.A N LEU 16.A O no hydrogen 3.019 N/A GLY 21.A N LEU 17.A O no hydrogen 2.688 N/A GLU 22.A N LEU 18.A O no hydrogen 2.935 N/A ILE 24.A N VAL 20.A O no hydrogen 2.858 N/A LYS 25.A N GLY 21.A O no hydrogen 2.764 N/A LYS 25.A NZ PHE 72.A O no hydrogen 2.742 N/A ARG 26.A N GLU 22.A O no hydrogen 3.040 N/A ARG 26.A NE GLU 23.A OE1 no hydrogen 2.926 N/A ARG 26.A NH1 GLU 242.A OE1 no hydrogen 2.898 N/A ARG 26.A NH2 GLU 23.A OE2 no hydrogen 2.886 N/A ARG 26.A NH2 GLU 242.A OE1 no hydrogen 2.608 N/A LEU 27.A N GLU 23.A O no hydrogen 2.939 N/A SER 28.A N ILE 24.A O no hydrogen 2.849 N/A SER 28.A OG ILE 24.A O no hydrogen 3.518 N/A SER 28.A OG LYS 25.A O no hydrogen 2.601 N/A GLU 29.A N LYS 25.A O no hydrogen 3.143 N/A GLU 29.A N ARG 26.A O no hydrogen 3.104 N/A LYS 30.A N ARG 26.A O no hydrogen 3.020 N/A PHE 31.A N LEU 27.A O no hydrogen 2.894 N/A LYS 32.A NZ GLU 29.A O no hydrogen 3.238 N/A GLU 33.A N GLU 33.A OE1 no hydrogen 2.619 N/A VAL 34.A N PHE 31.A O no hydrogen 3.018 N/A GLU 35.A N PHE 2.A O no hydrogen 2.843 N/A VAL 37.A N VAL 4.A O no hydrogen 2.926 N/A PHE 38.A N LYS 75.A O no hydrogen 2.945 N/A LYS 39.A N ALA 6.A O no hydrogen 2.796 N/A LYS 39.A NZ ASN 9.A O no hydrogen 3.156 N/A LYS 39.A NZ SER 41.A OG no hydrogen 3.118 N/A LYS 39.A NZ GLU 220.A OE2 no hydrogen 3.290 N/A SER 40.A OG PRO 8.A O no hydrogen 3.005 N/A SER 41.A N ASN 9.A O no hydrogen 2.941 N/A SER 41.A OG ASN 9.A O no hydrogen 3.109 N/A SER 41.A OG ASP 79.A OD1 no hydrogen 3.048 N/A LYS 44.A N ARG 54.A O no hydrogen 2.802 N/A LYS 44.A NZ SER 41.A OG no hydrogen 3.116 N/A ARG 47.A NH1 PHE 53.A O no hydrogen 2.972 N/A ARG 47.A NH1 LEU 229.A O no hydrogen 3.094 N/A HIS 51.A N SER 49.A OG no hydrogen 2.937 N/A SER 52.A N SER 49.A O no hydrogen 3.240 N/A ARG 54.A NE ASP 43.A OD1 no hydrogen 3.110 N/A ARG 54.A NH2 ASP 43.A OD1 no hydrogen 3.472 N/A ARG 54.A NH2 ASP 43.A OD2 no hydrogen 2.810 N/A HIS 56.A NE2 GLU 12.A O no hydrogen 2.890 N/A GLY 61.A N GLY 57.A O no hydrogen 3.061 N/A VAL 62.A N LEU 58.A O no hydrogen 2.845 N/A LYS 63.A N GLU 59.A O no hydrogen 3.138 N/A ALA 64.A N TYR 60.A O no hydrogen 2.926 N/A LEU 65.A N GLY 61.A O no hydrogen 2.902 N/A ARG 66.A N VAL 62.A O no hydrogen 2.970 N/A LYS 67.A N LYS 63.A O no hydrogen 3.089 N/A LYS 67.A NZ GLU 14.A OE2 no hydrogen 3.273 N/A VAL 68.A N ALA 64.A O no hydrogen 3.266 N/A LYS 69.A N LEU 65.A O no hydrogen 2.993 N/A LYS 69.A NZ VAL 92.A O no hydrogen 2.797 N/A LYS 69.A NZ ASP 94.A OD2 no hydrogen 2.847 N/A GLU 70.A N ARG 66.A O no hydrogen 2.916 N/A GLU 71.A N LYS 67.A O no hydrogen 2.862 N/A PHE 72.A N VAL 68.A O no hydrogen 2.841 N/A LYS 75.A NZ GLU 35.A OE2 no hydrogen 2.848 N/A ILE 76.A N ASP 94.A OD2 no hydrogen 2.700 N/A THR 77.A N PHE 38.A O no hydrogen 3.036 N/A THR 77.A OG1 ILE 95.A O no hydrogen 2.627 N/A THR 78.A OG1 SER 40.A O no hydrogen 2.703 N/A ASP 79.A N ASP 79.A OD1 no hydrogen 2.640 N/A ILE 80.A N GLN 97.A O no hydrogen 3.050 N/A HIS 81.A N GLN 85.A OE1 no hydrogen 2.738 N/A GLU 82.A N GLN 85.A OE1 no hydrogen 3.406 N/A GLN 85.A N GLU 82.A O no hydrogen 2.984 N/A ALA 86.A N SER 83.A O no hydrogen 3.307 N/A VAL 89.A N GLN 85.A O no hydrogen 3.111 N/A ALA 90.A N ALA 86.A O no hydrogen 2.851 N/A GLU 91.A N PRO 88.A O no hydrogen 3.229 N/A VAL 92.A N VAL 89.A O no hydrogen 2.970 N/A ALA 93.A N VAL 89.A O no hydrogen 2.875 N/A ASP 94.A N ILE 76.A O no hydrogen 2.555 N/A ILE 95.A N ILE 76.A O no hydrogen 3.137 N/A ILE 96.A N ALA 118.A O no hydrogen 2.823 N/A GLN 97.A N THR 78.A O no hydrogen 2.856 N/A ILE 98.A N ASN 120.A O no hydrogen 2.850 N/A LEU 102.A N PRO 99.A O no hydrogen 3.020 N/A CYS 103.A N ALA 100.A O no hydrogen 3.244 N/A CYS 103.A SG ALA 100.A O no hydrogen 3.296 N/A GLN 105.A N LEU 102.A O no hydrogen 3.045 N/A LEU 108.A N GLN 105.A O no hydrogen 3.045 N/A LEU 109.A N GLN 105.A O no hydrogen 3.183 N/A LEU 110.A N THR 106.A O no hydrogen 2.906 N/A ALA 111.A N ASP 107.A O no hydrogen 2.893 N/A ALA 112.A N LEU 108.A O no hydrogen 3.088 N/A ALA 113.A N LEU 109.A O no hydrogen 3.023 N/A LYS 114.A N LEU 110.A O no hydrogen 2.995 N/A THR 115.A N ALA 112.A O no hydrogen 3.199 N/A THR 115.A OG1 ALA 112.A O no hydrogen 2.655 N/A GLY 116.A N ALA 113.A O no hydrogen 3.156 N/A ARG 117.A N THR 115.A OG1 no hydrogen 3.278 N/A ARG 117.A NE ALA 90.A O no hydrogen 2.844 N/A ARG 117.A NH2 ALA 90.A O no hydrogen 3.147 N/A ALA 118.A N ASP 94.A O no hydrogen 3.349 N/A VAL 119.A N GLU 146.A O no hydrogen 3.082 N/A ASN 120.A N ILE 96.A O no hydrogen 2.910 N/A VAL 121.A N TYR 148.A O no hydrogen 2.977 N/A LYS 122.A N ILE 98.A O no hydrogen 2.995 N/A LYS 122.A NZ ASP 180.A OD2 no hydrogen 2.960 N/A LYS 123.A N THR 150.A O no hydrogen 2.931 N/A LYS 123.A NZ GLU 151.A OE1 no hydrogen 2.763 N/A GLN 125.A N GLN 125.A OE1 no hydrogen 2.554 N/A LEU 127.A N GLY 124.A O no hydrogen 3.061 N/A ALA 128.A N ASP 131.A OD2 no hydrogen 2.941 N/A ASP 131.A N ALA 128.A O no hydrogen 2.733 N/A THR 132.A N PRO 129.A O no hydrogen 3.216 N/A THR 132.A OG1 PRO 129.A O no hydrogen 2.708 N/A LYS 133.A N TRP 130.A O no hydrogen 3.409 N/A VAL 136.A N THR 132.A O no hydrogen 3.059 N/A GLU 137.A N LYS 133.A O no hydrogen 2.956 N/A LYS 138.A N ASN 134.A O no hydrogen 2.868 N/A LYS 138.A NZ THR 106.A OG1 no hydrogen 3.167 N/A LEU 139.A N VAL 135.A O no hydrogen 3.109 N/A LYS 140.A N VAL 136.A O no hydrogen 2.893 N/A PHE 141.A N GLU 137.A O no hydrogen 3.029 N/A GLY 142.A N LYS 138.A O no hydrogen 2.961 N/A GLY 143.A N LYS 140.A O no hydrogen 2.906 N/A ALA 144.A N LEU 139.A O no hydrogen 2.978 N/A TYR 148.A N VAL 119.A O no hydrogen 2.851 N/A TYR 148.A OH GLU 146.A OE2 no hydrogen 2.860 N/A LEU 149.A N LYS 176.A O no hydrogen 2.933 N/A THR 150.A N VAL 121.A O no hydrogen 2.896 N/A THR 150.A OG1 ASN 120.A OD1 no hydrogen 2.562 N/A GLU 151.A N ILE 178.A O no hydrogen 2.746 N/A ARG 152.A NE ARG 152.A O no hydrogen 2.755 N/A ARG 152.A NH1 GLN 186.A OE1 no hydrogen 3.458 N/A ARG 152.A NH2 ARG 152.A O no hydrogen 3.507 N/A ARG 152.A NH2 GLN 186.A OE1 no hydrogen 2.684 N/A GLY 153.A N GLU 151.A OE2 no hydrogen 2.736 N/A THR 154.A N VAL 162.A O no hydrogen 2.894 N/A THR 155.A N GLN 125.A O no hydrogen 3.058 N/A THR 155.A OG1 GLN 125.A O no hydrogen 3.200 N/A PHE 156.A N ASN 160.A O no hydrogen 2.954 N/A ASN 159.A ND2 PRO 188.A O no hydrogen 2.524 N/A VAL 162.A N THR 154.A O no hydrogen 3.004 N/A ARG 166.A N ASP 164.A OD1 no hydrogen 2.979 N/A ARG 166.A NE ASP 164.A OD1 no hydrogen 2.794 N/A ARG 166.A NE ASP 164.A OD2 no hydrogen 3.178 N/A ARG 166.A NH2 ASP 164.A OD2 no hydrogen 2.649 N/A SER 167.A N ASP 164.A O no hydrogen 2.949 N/A SER 167.A OG GLU 151.A OE1 no hydrogen 2.711 N/A SER 167.A OG ASP 164.A O no hydrogen 3.331 N/A LEU 168.A N PHE 165.A O no hydrogen 3.352 N/A ILE 170.A N ARG 166.A O no hydrogen 3.412 N/A MET 171.A N SER 167.A O no hydrogen 2.786 N/A LYS 172.A N LEU 168.A O no hydrogen 3.052 N/A LYS 172.A NZ ASP 215.A OD1 no hydrogen 3.164 N/A GLN 173.A N ILE 170.A O no hydrogen 3.330 N/A GLN 173.A NE2 ILE 170.A O no hydrogen 2.799 N/A TRP 174.A N MET 171.A O no hydrogen 2.991 N/A ALA 175.A N MET 171.A O no hydrogen 3.216 N/A LYS 176.A N ILE 147.A O no hydrogen 3.441 N/A VAL 177.A N ASP 215.A OD2 no hydrogen 2.797 N/A ILE 178.A N LEU 149.A O no hydrogen 2.870 N/A TYR 179.A N GLY 216.A O no hydrogen 3.038 N/A ASP 180.A N GLU 151.A O no hydrogen 2.858 N/A ALA 181.A N PHE 218.A O no hydrogen 2.896 N/A HIS 183.A N ASP 180.A OD1 no hydrogen 2.823 N/A HIS 183.A ND1 ASP 180.A OD2 no hydrogen 2.731 N/A SER 184.A OG ASP 180.A O no hydrogen 2.780 N/A GLN 186.A N HIS 183.A O no hydrogen 2.917 N/A LEU 187.A N GLY 196.A O no hydrogen 2.863 N/A GLY 189.A N SER 195.A OG no hydrogen 3.076 N/A GLY 190.A N LEU 187.A O no hydrogen 2.935 N/A LEU 191.A N LYS 194.A O no hydrogen 2.911 N/A GLY 192.A N GLY 189.A O no hydrogen 3.216 N/A GLY 196.A N LEU 187.A O no hydrogen 3.093 N/A MET 198.A N VAL 185.A O no hydrogen 3.043 N/A GLU 200.A N GLU 200.A OE1 no hydrogen 2.424 N/A PHE 201.A N MET 198.A O no hydrogen 3.141 N/A ILE 202.A N ARG 199.A O no hydrogen 3.118 N/A LEU 205.A N PHE 201.A O no hydrogen 3.091 N/A ILE 206.A N ILE 202.A O no hydrogen 3.134 N/A ILE 206.A N PHE 203.A O no hydrogen 2.991 N/A ARG 207.A N PHE 203.A O no hydrogen 3.050 N/A ALA 208.A N PRO 204.A O no hydrogen 3.181 N/A ALA 209.A N LEU 205.A O no hydrogen 3.023 N/A VAL 210.A N ILE 206.A O no hydrogen 3.092 N/A ALA 211.A N ARG 207.A O no hydrogen 2.922 N/A VAL 212.A N ALA 208.A O no hydrogen 2.767 N/A GLY 213.A N ALA 209.A O no hydrogen 2.771 N/A CYS 214.A SG ALA 209.A O no hydrogen 3.929 N/A CYS 214.A SG GLY 216.A O no hydrogen 3.472 N/A ASP 215.A N VAL 177.A O no hydrogen 2.716 N/A VAL 217.A N LEU 3.A O no hydrogen 2.874 N/A PHE 218.A N TYR 179.A O no hydrogen 2.757 N/A MET 219.A N ILE 5.A O no hydrogen 2.792 N/A GLU 220.A N THR 182.A OG1 no hydrogen 2.894 N/A THR 221.A N GLY 7.A O no hydrogen 2.834 N/A THR 221.A OG1 LEU 236.A O no hydrogen 2.806 N/A HIS 222.A N LEU 236.A O no hydrogen 2.990 N/A HIS 222.A NE2 GLU 12.A OE1 no hydrogen 3.259 N/A GLU 224.A N HIS 222.A ND1 no hydrogen 2.883 N/A LYS 227.A N GLU 224.A O no hydrogen 2.788 N/A LYS 227.A NZ GLU 224.A OE2 no hydrogen 3.400 N/A ALA 228.A N PRO 225.A O no hydrogen 3.061 N/A LEU 229.A N GLU 12.A OE2 no hydrogen 2.835 N/A THR 234.A N ASP 231.A O no hydrogen 2.860 N/A THR 234.A OG1 ASP 231.A O no hydrogen 2.831 N/A ALA 235.A N ALA 232.A O no hydrogen 3.214 N/A LEU 236.A N GLU 220.A O no hydrogen 3.126 N/A LEU 238.A N HIS 222.A O no hydrogen 3.011 N/A GLN 240.A N PRO 237.A O no hydrogen 2.905 N/A LEU 241.A N LEU 238.A O no hydrogen 3.466 N/A ILE 244.A N GLN 240.A O no hydrogen 3.387 N/A ILE 245.A N LEU 241.A O no hydrogen 2.896 N/A GLU 246.A N GLU 242.A O no hydrogen 2.961 N/A ALA 247.A N GLY 243.A O no hydrogen 3.113 N/A ILE 248.A N ILE 244.A O no hydrogen 2.960 N/A LEU 249.A N ILE 245.A O no hydrogen 3.068 N/A GLU 250.A N GLU 246.A O no hydrogen 3.033 N/A ILE 251.A N ALA 247.A O no hydrogen 2.850 N/A ARG 252.A N ILE 248.A O no hydrogen 2.803 N/A GLU 253.A N LEU 249.A O no hydrogen 2.908 N/A VAL 254.A N GLU 250.A O no hydrogen 3.491 N/A ALA 255.A N ILE 251.A O no hydrogen 2.937 N/A SER 256.A N ARG 252.A O no hydrogen 2.787 N/A SER 256.A OG ARG 252.A O no hydrogen 2.980 N/A SER 256.A OG GLU 253.A O no hydrogen 2.721 N/A LYS 257.A NZ VAL 254.A O no hydrogen 2.848 N/A TYR 258.A N ALA 255.A O no hydrogen 2.819 N/A TYR 259.A N SER 256.A O no hydrogen 3.156 N/A TYR 259.A OH VAL 210.A O no hydrogen 2.580 N/A GLU 260.A N GLU 260.A OE1 no hydrogen 2.612 N/A