Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2nxy_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 1.A N THR 98.A O no hydrogen 3.345 N/A VAL 2.A N THR 98.A O no hydrogen 3.106 N/A LEU 4.A N VAL 96.A O no hydrogen 2.821 N/A GLU 9.A N CYS 93.A O no hydrogen 3.152 N/A PHE 11.A N GLY 91.A O no hydrogen 2.870 N/A MET 13.A N GLY 89.A O no hydrogen 2.907 N/A TRP 14.A N ASN 12.A OD1 no hydrogen 3.077 N/A LYS 15.A N ASN 12.A O no hydrogen 2.976 N/A MET 18.A N ASN 16.A OD1 no hydrogen 3.072 N/A VAL 19.A N ASN 16.A O no hydrogen 2.935 N/A GLN 21.A N ASP 17.A O no hydrogen 2.966 N/A GLN 21.A NE2 ASP 25.A OD1 no hydrogen 3.288 N/A GLN 21.A NE2 ASP 25.A OD2 no hydrogen 3.311 N/A MET 22.A N MET 18.A O no hydrogen 3.015 N/A HIS 23.A N VAL 19.A O no hydrogen 2.909 N/A GLU 24.A N GLU 20.A O no hydrogen 3.150 N/A ASP 25.A N GLN 21.A O no hydrogen 3.039 N/A ILE 26.A N MET 22.A O no hydrogen 2.924 N/A ILE 27.A N HIS 23.A O no hydrogen 3.067 N/A SER 28.A N GLU 24.A O no hydrogen 3.106 N/A SER 28.A OG GLU 24.A O no hydrogen 3.082 N/A LEU 29.A N ASP 25.A O no hydrogen 3.006 N/A TRP 30.A N ILE 26.A O no hydrogen 2.991 N/A ASP 31.A N ILE 27.A O no hydrogen 3.117 N/A GLN 32.A N SER 28.A O no hydrogen 3.147 N/A SER 33.A N LEU 29.A O no hydrogen 2.945 N/A LEU 34.A N TRP 30.A O no hydrogen 2.760 N/A LYS 35.A NZ ASP 31.A O no hydrogen 2.759 N/A CYS 37.A N MET 247.A O no hydrogen 2.648 N/A VAL 38.A N MET 247.A O no hydrogen 3.419 N/A LYS 39.A N ILE 55.A O no hydrogen 2.772 N/A LEU 40.A N LYS 245.A O no hydrogen 2.781 N/A THR 41.A N SER 53.A O no hydrogen 3.018 N/A ASN 51.A N LEU 43.A O no hydrogen 2.967 N/A SER 53.A N THR 41.A O no hydrogen 2.790 N/A ILE 55.A N LYS 39.A O no hydrogen 2.875 N/A GLN 57.A N CYS 37.A O no hydrogen 3.137 N/A GLN 57.A NE2 PRO 36.A O no hydrogen 3.187 N/A LYS 61.A NZ GLU 206.A OE1 no hydrogen 3.502 N/A LYS 61.A NZ GLU 206.A OE2 no hydrogen 2.666 N/A LYS 61.A NZ ALA 249.A O no hydrogen 3.139 N/A LYS 61.A NZ PRO 250.A O no hydrogen 3.471 N/A ILE 69.A N ILE 105.A O no hydrogen 2.693 N/A TYR 71.A N THR 102.A OG1 no hydrogen 3.096 N/A TYR 71.A OH ASP 25.A OD2 no hydrogen 2.507 N/A PHE 77.A N PRO 74.A O no hydrogen 2.906 N/A ALA 78.A N VAL 302.A O no hydrogen 2.713 N/A LEU 80.A N LYS 300.A O no hydrogen 2.821 N/A LYS 81.A N SER 97.A O no hydrogen 2.767 N/A CYS 82.A N LYS 298.A O no hydrogen 2.872 N/A ASN 83.A N ASN 95.A O no hydrogen 2.757 N/A ASN 83.A ND2 ASN 95.A OD1 no hydrogen 3.062 N/A ASN 83.A ND2 SER 97.A OG no hydrogen 2.706 N/A THR 86.A N ASN 84.A OD1 no hydrogen 2.848 N/A THR 86.A OG1 GLU 122.A OE1 no hydrogen 2.396 N/A PHE 87.A N ASN 84.A O no hydrogen 3.269 N/A THR 90.A N ASN 88.A OD1 no hydrogen 2.971 N/A GLY 91.A N PHE 11.A O no hydrogen 2.953 N/A CYS 93.A N GLU 9.A O no hydrogen 2.805 N/A CYS 93.A SG ASN 95.A O no hydrogen 3.300 N/A SER 97.A N LYS 81.A O no hydrogen 2.827 N/A THR 98.A N VAL 2.A O no hydrogen 2.986 N/A VAL 99.A N ILE 79.A O no hydrogen 3.092 N/A THR 102.A N TYR 71.A O no hydrogen 2.852 N/A THR 102.A OG1 HIS 103.A O no hydrogen 2.872 N/A HIS 103.A N TYR 299.A OH no hydrogen 2.975 N/A HIS 103.A ND1 TYR 299.A OH no hydrogen 2.776 N/A HIS 103.A NE2 GLU 295.A OE1 no hydrogen 2.788 N/A ILE 105.A N ILE 69.A O no hydrogen 2.800 N/A VAL 108.A N ARG 106.A O no hydrogen 2.886 N/A SER 110.A OG LEU 113.A O no hydrogen 2.673 N/A THR 111.A N SER 200.A O no hydrogen 2.957 N/A THR 111.A OG1 GLU 195.A O no hydrogen 2.731 N/A THR 111.A OG1 THR 198.A O no hydrogen 2.968 N/A THR 111.A OG1 SER 200.A OG no hydrogen 3.147 N/A GLN 112.A N GLY 284.A O no hydrogen 2.828 N/A GLN 112.A NE2 ILE 196.A O no hydrogen 2.998 N/A GLN 112.A NE2 VAL 197.A O no hydrogen 3.062 N/A LEU 113.A N THR 111.A O no hydrogen 2.717 N/A LEU 114.A N GLY 264.A O no hydrogen 2.864 N/A ASN 116.A N ASN 261.A O no hydrogen 2.835 N/A GLY 117.A N THR 263.A OG1 no hydrogen 3.103 N/A SER 118.A N GLU 295.A OE2 no hydrogen 2.760 N/A SER 118.A OG HIS 103.A NE2 no hydrogen 3.406 N/A SER 118.A OG GLU 295.A OE1 no hydrogen 2.851 N/A ALA 120.A N LEU 142.A O no hydrogen 2.765 N/A VAL 125.A N GLN 141.A O no hydrogen 3.077 N/A ARG 127.A N ILE 139.A O no hydrogen 2.803 N/A ARG 127.A NE PHE 87.A O no hydrogen 3.174 N/A ARG 127.A NH1 GLN 141.A OE1 no hydrogen 3.131 N/A ARG 127.A NH2 PHE 87.A O no hydrogen 2.565 N/A ASN 130.A N SER 128.A OG no hydrogen 3.191 N/A THR 132.A N ASN 130.A OD1 no hydrogen 3.263 N/A THR 132.A OG1 ASN 130.A OD1 no hydrogen 3.504 N/A ASP 133.A N ASN 130.A O no hydrogen 3.072 N/A ASN 134.A ND2 ASP 270.A O no hydrogen 2.886 N/A ALA 135.A N ASP 133.A OD2 no hydrogen 3.044 N/A LYS 136.A N ASP 133.A O no hydrogen 3.175 N/A THR 137.A OG1 ASP 290.A OD2 no hydrogen 3.560 N/A ILE 138.A N LEU 267.A O no hydrogen 2.696 N/A ILE 139.A N ARG 127.A O no hydrogen 2.784 N/A VAL 140.A N LEU 265.A O no hydrogen 2.883 N/A GLN 141.A N VAL 125.A O no hydrogen 2.811 N/A GLN 141.A NE2 SER 118.A O no hydrogen 3.441 N/A LEU 142.A N THR 263.A O no hydrogen 2.923 N/A ASN 143.A ND2 GLU 122.A O no hydrogen 2.723 N/A THR 144.A OG1 ASN 143.A OD1 no hydrogen 3.540 N/A VAL 146.A N ILE 262.A O no hydrogen 3.037 N/A ILE 148.A N SER 260.A O no hydrogen 2.933 N/A ASN 149.A N ASN 157.A O no hydrogen 2.937 N/A CYS 150.A N CYS 258.A O no hydrogen 2.882 N/A THR 151.A N HIS 155.A O no hydrogen 2.930 N/A THR 151.A OG1 ILE 256.A O no hydrogen 3.500 N/A GLY 152.A N ILE 256.A O no hydrogen 2.760 N/A ALA 153.A N THR 151.A OG1 no hydrogen 3.029 N/A GLY 154.A N THR 151.A O no hydrogen 3.049 N/A CYS 156.A N LEU 229.A O no hydrogen 2.918 N/A ASN 157.A N ASN 149.A O no hydrogen 2.625 N/A ILE 158.A N ILE 227.A O no hydrogen 2.886 N/A ARG 160.A N ASP 225.A O no hydrogen 3.232 N/A ARG 160.A NE SER 224.A O no hydrogen 2.695 N/A LYS 162.A NZ GLU 147.A OE1.A no hydrogen 3.003 N/A LYS 162.A NZ GLU 147.A OE2.A no hydrogen 3.564 N/A TRP 163.A N ALA 159.A O no hydrogen 3.110 N/A TRP 163.A NE1 LEU 215.A O no hydrogen 2.965 N/A ASN 164.A N ARG 160.A O no hydrogen 2.914 N/A ASN 165.A N ALA 161.A O no hydrogen 2.998 N/A THR 166.A N LYS 162.A O no hydrogen 3.031 N/A THR 166.A OG1 LYS 162.A O no hydrogen 2.955 N/A LEU 167.A N TRP 163.A O no hydrogen 2.933 N/A LYS 168.A N ASN 164.A O no hydrogen 3.195 N/A GLN 169.A N ASN 165.A O no hydrogen 3.186 N/A ILE 170.A N THR 166.A O no hydrogen 2.991 N/A ALA 171.A N LEU 167.A O no hydrogen 2.839 N/A SER 172.A N LYS 168.A O no hydrogen 3.085 N/A LYS 173.A N GLN 169.A O no hydrogen 3.219 N/A LYS 173.A NZ GLU 123.A OE2 no hydrogen 2.765 N/A LYS 173.A NZ GLU 176.A OE1 no hydrogen 3.417 N/A LEU 174.A N ILE 170.A O no hydrogen 2.877 N/A ARG 175.A N ALA 171.A O no hydrogen 2.795 N/A ARG 175.A NE ASN 180.A O no hydrogen 2.758 N/A ARG 175.A NH1 ASN 180.A O no hydrogen 2.165 N/A GLU 176.A N SER 172.A O no hydrogen 3.168 N/A GLN 177.A N LYS 173.A O no hydrogen 3.213 N/A GLN 177.A N LEU 174.A O no hydrogen 3.277 N/A PHE 178.A N LEU 174.A O no hydrogen 2.870 N/A GLY 179.A N ARG 175.A O no hydrogen 2.688 N/A LYS 182.A N GLY 179.A O no hydrogen 3.241 N/A LYS 182.A NZ GLU 277.A OE2 no hydrogen 2.914 N/A THR 183.A N GLU 277.A O no hydrogen 3.053 N/A THR 183.A OG1 ASN 222.A OD1 no hydrogen 3.570 N/A ILE 184.A N TRP 220.A O no hydrogen 2.997 N/A ILE 185.A N GLU 279.A O no hydrogen 2.913 N/A PHE 186.A N SER 218.A O no hydrogen 2.834 N/A LYS 187.A N PHE 281.A O no hydrogen 2.971 N/A GLY 191.A N SER 189.A OG no hydrogen 3.348 N/A GLU 195.A N GLU 195.A OE2 no hydrogen 2.790 N/A ILE 196.A N ASP 193.A O no hydrogen 3.019 N/A VAL 197.A N ASP 193.A O no hydrogen 2.970 N/A THR 198.A N PRO 194.A O no hydrogen 3.130 N/A THR 198.A OG1 PRO 194.A O no hydrogen 2.786 N/A HIS 199.A N CYS 210.A O no hydrogen 2.983 N/A HIS 199.A ND1 THR 111.A O no hydrogen 2.853 N/A SER 200.A N THR 111.A OG1 no hydrogen 3.112 N/A SER 200.A OG THR 111.A OG1 no hydrogen 3.147 N/A SER 200.A OG GLU 195.A O no hydrogen 2.842 N/A PHE 201.A N PHE 208.A O no hydrogen 3.261 N/A CYS 203.A N GLU 206.A O no hydrogen 2.883 N/A GLU 206.A N CYS 203.A O no hydrogen 2.954 N/A PHE 208.A N PHE 201.A O no hydrogen 2.856 N/A TYR 209.A N ARG 232.A O no hydrogen 2.839 N/A TYR 209.A OH GLU 195.A OE1 no hydrogen 2.605 N/A CYS 210.A N HIS 199.A O no hydrogen 2.898 N/A ASN 211.A N PRO 230.A O no hydrogen 2.934 N/A SER 212.A OG GLN 112.A OE1 no hydrogen 2.599 N/A THR 213.A N ASN 211.A OD1 no hydrogen 3.015 N/A THR 213.A OG1 GLN 188.A OE1 no hydrogen 2.703 N/A THR 213.A OG1 ASN 211.A OD1 no hydrogen 2.973 N/A GLN 214.A NE2 THR 228.A O no hydrogen 2.771 N/A LEU 215.A N SER 212.A O no hydrogen 2.882 N/A PHE 216.A N THR 213.A O no hydrogen 3.054 N/A SER 218.A N PHE 186.A O no hydrogen 3.241 N/A TRP 220.A N ILE 184.A O no hydrogen 2.673 N/A TRP 220.A NE1 SER 218.A OG no hydrogen 2.979 N/A SER 224.A OG THR 226.A O no hydrogen 3.543 N/A ILE 227.A N ILE 158.A O no hydrogen 2.628 N/A THR 228.A OG1 ASN 157.A OD1 no hydrogen 2.862 N/A LEU 229.A N CYS 156.A O no hydrogen 2.808 N/A CYS 231.A N GLY 154.A O no hydrogen 2.779 N/A CYS 231.A SG LEU 229.A O no hydrogen 3.557 N/A ARG 232.A N TYR 209.A O no hydrogen 2.996 N/A LYS 234.A N PHE 207.A O no hydrogen 2.953 N/A ILE 237.A N ALA 246.A O no hydrogen 2.988 N/A ASN 238.A N GLU 195.A OE1 no hydrogen 2.971 N/A ASN 238.A ND2 GLU 195.A OE2 no hydrogen 2.969 N/A MET 239.A N GLY 244.A O no hydrogen 2.953 N/A GLN 241.A N GLN 241.A OE1 no hydrogen 2.776 N/A LYS 245.A N LEU 40.A O no hydrogen 2.826 N/A LYS 245.A NZ ASN 238.A OD1 no hydrogen 2.775 N/A ALA 246.A N ILE 237.A O no hydrogen 2.937 N/A MET 247.A N VAL 38.A O no hydrogen 2.809 N/A TYR 248.A N GLN 235.A O no hydrogen 2.758 N/A TYR 248.A OH LEU 34.A O no hydrogen 3.264 N/A GLN 255.A N SER 253.A OG no hydrogen 3.104 N/A ARG 257.A NH2.A ILE 256.A O no hydrogen 3.481 N/A CYS 258.A N CYS 150.A O no hydrogen 3.117 N/A SER 260.A N ILE 148.A O no hydrogen 2.987 N/A ASN 261.A N ASN 116.A OD1 no hydrogen 3.162 N/A ILE 262.A N VAL 146.A O no hydrogen 2.717 N/A THR 263.A N LEU 114.A O no hydrogen 2.905 N/A THR 263.A OG1 LEU 114.A O no hydrogen 3.501 N/A GLY 264.A N LEU 114.A O no hydrogen 3.333 N/A LEU 265.A N VAL 140.A O no hydrogen 3.068 N/A LEU 266.A N GLN 112.A O no hydrogen 2.911 N/A LEU 267.A N ILE 138.A O no hydrogen 2.903 N/A THR 268.A N ARG 282.A O no hydrogen 2.941 N/A ARG 269.A NH1 PHE 131.A O no hydrogen 3.183 N/A ARG 269.A NH2 GLU 279.A OE2 no hydrogen 3.132 N/A ASP 270.A N ILE 280.A O no hydrogen 2.788 N/A ASN 276.A N SER 274.A OG no hydrogen 3.422 N/A SER 278.A OG ASN 276.A OD1 no hydrogen 2.536 N/A GLU 279.A N THR 183.A O no hydrogen 2.888 N/A PHE 281.A N ILE 185.A O no hydrogen 2.801 N/A ARG 282.A N THR 268.A O no hydrogen 2.968 N/A ARG 282.A NE ASP 270.A OD1 no hydrogen 3.240 N/A ARG 282.A NE ASP 270.A OD2 no hydrogen 2.783 N/A ARG 282.A NH1 GLN 188.A O no hydrogen 2.919 N/A ARG 282.A NH2 ASP 270.A OD1 no hydrogen 2.896 N/A GLY 284.A N LEU 266.A O no hydrogen 2.806 N/A ARG 289.A N ASP 287.A OD1 no hydrogen 3.056 N/A ARG 289.A NH1 ASP 287.A OD1 no hydrogen 2.903 N/A ASP 290.A N ASP 287.A O no hydrogen 3.010 N/A ASN 291.A ND2 VAL 108.A O no hydrogen 3.622 N/A ASN 291.A ND2 SER 110.A O no hydrogen 3.004 N/A TRP 292.A N MET 288.A O no hydrogen 3.099 N/A TRP 292.A NE1 HIS 23.A ND1 no hydrogen 3.011 N/A ARG 293.A N ARG 289.A O no hydrogen 2.762 N/A ARG 293.A NH1 ASP 290.A OD1 no hydrogen 2.733 N/A SER 294.A N ASP 290.A O no hydrogen 3.000 N/A SER 294.A OG ASN 291.A O no hydrogen 2.614 N/A GLU 295.A N TRP 292.A O no hydrogen 3.125 N/A LEU 296.A N TRP 292.A O no hydrogen 2.973 N/A TYR 299.A N LEU 296.A O no hydrogen 3.045 N/A TYR 299.A OH HIS 103.A ND1 no hydrogen 2.776 N/A LYS 300.A N LEU 80.A O no hydrogen 2.991 N/A LYS 300.A NZ GLU 9.A OE2 no hydrogen 2.870 N/A LYS 300.A NZ ASN 10.A O no hydrogen 2.867 N/A VAL 302.A N ALA 78.A O no hydrogen 2.888 N/A LYS 303.A NZ ILE 304.A O no hydrogen 3.538 N/A ILE 304.A N GLY 76.A O no hydrogen 3.120 N/A