Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2nyz_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): HIS 1.A N HIS 1.A ND1 no hydrogen 2.596 N/A SER 2.A OG GLN 197.A OE1 no hydrogen 3.049 N/A SER 3.A OG PRO 198.A O no hydrogen 3.454 N/A GLY 4.A N LYS 60.A O no hydrogen 3.071 N/A SER 6.A N LYS 58.A O no hydrogen 2.949 N/A THR 7.A OG1 PRO 282.A O no hydrogen 2.540 N/A GLN 8.A N ASN 56.A O no hydrogen 3.108 N/A GLN 8.A NE2 GLN 52.A O no hydrogen 3.044 N/A GLN 8.A NE2 CYS 55.A O no hydrogen 2.775 N/A SER 13.A N ASP 11.A OD1 no hydrogen 3.096 N/A GLN 14.A N ASP 11.A O no hydrogen 2.871 N/A ILE 15.A N LEU 12.A O no hydrogen 3.112 N/A LYS 16.A N GLU 50.A OE2 no hydrogen 3.036 N/A ARG 17.A NE GLU 20.A OE2 no hydrogen 2.601 N/A ARG 17.A NH1 ASP 42.A OD2 no hydrogen 2.753 N/A ARG 17.A NH2 GLU 20.A OE1 no hydrogen 2.715 N/A ARG 17.A NH2 GLU 20.A OE2 no hydrogen 3.189 N/A GLY 18.A N ILE 15.A O no hydrogen 2.888 N/A GLU 20.A N ARG 17.A O no hydrogen 3.052 N/A ILE 21.A N ARG 17.A O no hydrogen 3.201 N/A GLN 22.A N GLY 18.A O no hydrogen 3.003 N/A ALA 23.A N GLU 20.A O no hydrogen 2.932 N/A HIS 24.A N GLU 20.A O no hydrogen 2.960 N/A HIS 24.A N ILE 21.A O no hydrogen 3.402 N/A CYS 25.A N ILE 21.A O no hydrogen 2.717 N/A CYS 25.A SG CYS 36.A O no hydrogen 3.616 N/A LEU 26.A N ILE 21.A O no hydrogen 3.055 N/A THR 27.A OG1 GLN 22.A O no hydrogen 2.527 N/A ALA 37.A N VAL 33.A O no hydrogen 2.624 N/A GLY 38.A N THR 34.A O no hydrogen 2.816 N/A GLY 38.A N GLU 35.A O no hydrogen 2.772 N/A ILE 39.A N GLU 35.A O no hydrogen 3.162 N/A LEU 40.A N CYS 36.A O no hydrogen 2.942 N/A LYS 41.A N ALA 37.A O no hydrogen 2.951 N/A LYS 41.A N GLY 38.A O no hydrogen 2.996 N/A ASP 42.A N GLY 38.A O no hydrogen 3.190 N/A VAL 43.A N ILE 39.A O no hydrogen 2.976 N/A LEU 44.A N LEU 40.A O no hydrogen 2.895 N/A SER 45.A N LYS 41.A O no hydrogen 3.189 N/A SER 45.A N ASP 42.A O no hydrogen 3.133 N/A SER 45.A OG LYS 41.A O no hydrogen 2.510 N/A LYS 46.A NZ ASP 42.A OD1 no hydrogen 2.630 N/A ASN 47.A N VAL 43.A O no hydrogen 3.165 N/A GLU 50.A N ASN 47.A O no hydrogen 3.237 N/A GLN 52.A N HIS 49.A O no hydrogen 3.076 N/A GLY 53.A N GLU 50.A O no hydrogen 3.360 N/A LEU 54.A N LEU 51.A O no hydrogen 2.897 N/A CYS 55.A N GLN 52.A O no hydrogen 3.402 N/A ASN 56.A ND2 THR 180.A O no hydrogen 3.203 N/A ASN 56.A ND2 TYR 284.A OH no hydrogen 2.994 N/A VAL 57.A N THR 182.A O no hydrogen 3.460 N/A LYS 58.A N SER 6.A O no hydrogen 2.885 N/A ASN 59.A N CYS 184.A O no hydrogen 2.781 N/A ASN 59.A ND2 SER 201.A OG no hydrogen 2.926 N/A ASN 59.A ND2 GLN 362.A OE1 no hydrogen 2.888 N/A LYS 60.A N GLY 4.A O no hydrogen 3.040 N/A LYS 60.A NZ HIS 1.A O no hydrogen 2.774 N/A MET 61.A N GLU 186.A O no hydrogen 2.900 N/A GLY 62.A N GLN 197.A O no hydrogen 2.753 N/A VAL 63.A N GLY 188.A O no hydrogen 2.838 N/A TRP 65.A N ILE 190.A O no hydrogen 3.108 N/A VAL 66.A N ILE 75.A O no hydrogen 2.726 N/A SER 67.A OG GLU 74.A OE1 no hydrogen 2.866 N/A SER 67.A OG GLU 74.A OE2 no hydrogen 3.002 N/A SER 67.A OG GLU 192.A OE2 no hydrogen 3.360 N/A VAL 68.A N GLN 73.A O no hydrogen 2.927 N/A GLU 70.A N GLU 70.A OE2 no hydrogen 2.716 N/A LEU 71.A N VAL 68.A O no hydrogen 2.856 N/A GLY 72.A N GLU 69.A O no hydrogen 3.025 N/A GLN 73.A N VAL 68.A O no hydrogen 3.266 N/A GLU 74.A N PHE 162.A O no hydrogen 2.945 N/A ILE 75.A N VAL 66.A O no hydrogen 2.767 N/A ILE 76.A N ALA 160.A O no hydrogen 2.848 N/A THR 77.A OG1 THR 158.A O no hydrogen 3.346 N/A GLY 78.A N THR 158.A O no hydrogen 2.783 N/A PHE 82.A N LEU 80.A O no hydrogen 2.922 N/A GLY 86.A N ASP 153.A OD2 no hydrogen 3.031 N/A THR 88.A N ASN 91.A OD1 no hydrogen 3.007 N/A ASN 91.A N THR 88.A O no hydrogen 3.120 N/A ASN 91.A ND2 LEU 304.A O no hydrogen 2.804 N/A VAL 94.A N ILE 147.A O no hydrogen 2.876 N/A ARG 95.A NH1 GLU 30.A O no hydrogen 3.231 N/A ARG 95.A NH2 GLU 30.A O no hydrogen 2.995 N/A VAL 96.A N ILE 145.A O no hydrogen 2.887 N/A LEU 97.A N MET 174.A O no hydrogen 3.247 N/A VAL 98.A N TRP 143.A O no hydrogen 3.089 N/A VAL 99.A N THR 172.A O no hydrogen 2.728 N/A ALA 100.A N THR 141.A O no hydrogen 2.903 N/A GLU 101.A N LYS 170.A O no hydrogen 3.104 N/A SER 102.A N TYR 139.A O no hydrogen 3.391 N/A SER 102.A OG ASN 103.A O no hydrogen 3.326 N/A ASN 103.A N PRO 167.A O no hydrogen 3.010 N/A TYR 116.A N THR 161.A O no hydrogen 2.973 N/A GLU 118.A N ARG 159.A O no hydrogen 2.879 N/A LEU 119.A N PHE 126.A O no hydrogen 2.789 N/A GLN 120.A N LEU 157.A O no hydrogen 2.915 N/A THR 121.A N TYR 124.A O no hydrogen 2.865 N/A THR 121.A OG1 TYR 124.A O no hydrogen 2.844 N/A TYR 124.A N THR 121.A OG1 no hydrogen 3.185 N/A PHE 126.A N LEU 119.A O no hydrogen 2.764 N/A LEU 128.A N VAL 117.A O no hydrogen 2.956 N/A SER 129.A N ASN 132.A OD1 no hydrogen 2.842 N/A SER 129.A OG ASP 131.A OD1 no hydrogen 3.493 N/A SER 129.A OG ASN 132.A OD1 no hydrogen 2.621 N/A ASN 132.A N SER 129.A O no hydrogen 2.594 N/A ASN 132.A ND2 MET 144.A O no hydrogen 3.085 N/A VAL 133.A N ASP 130.A O no hydrogen 3.292 N/A VAL 134.A N VAL 142.A O no hydrogen 2.796 N/A THR 141.A N ALA 100.A O no hydrogen 2.862 N/A VAL 142.A N PHE 135.A O no hydrogen 3.007 N/A TRP 143.A N VAL 98.A O no hydrogen 2.830 N/A MET 144.A N ASN 132.A O no hydrogen 3.013 N/A ILE 145.A N VAL 96.A O no hydrogen 3.185 N/A ILE 147.A N VAL 94.A O no hydrogen 3.224 N/A LYS 149.A N ASP 92.A O no hydrogen 3.256 N/A TYR 151.A N PRO 148.A O no hydrogen 2.951 N/A VAL 152.A N LYS 149.A O no hydrogen 2.845 N/A ASP 153.A N TYR 151.A O no hydrogen 3.103 N/A VAL 154.A N ASP 153.A OD1 no hydrogen 2.557 N/A MET 156.A N ASP 153.A O no hydrogen 2.985 N/A LEU 157.A N GLN 120.A O no hydrogen 2.833 N/A THR 158.A N GLY 78.A O no hydrogen 2.893 N/A ARG 159.A N GLU 118.A O no hydrogen 2.983 N/A ALA 160.A N ILE 76.A O no hydrogen 2.766 N/A THR 161.A N TYR 116.A O no hydrogen 2.822 N/A PHE 162.A N GLU 74.A O no hydrogen 2.834 N/A GLN 165.A NE2 GLU 74.A OE1 no hydrogen 2.693 N/A GLN 165.A NE2 GLU 192.A OE2 no hydrogen 3.557 N/A ALA 169.A N TRP 166.A O no hydrogen 2.939 N/A LYS 170.A N GLU 101.A O no hydrogen 3.078 N/A LYS 170.A NZ GLU 186.A OE1 no hydrogen 3.199 N/A VAL 171.A N LEU 187.A O no hydrogen 3.055 N/A THR 172.A N VAL 99.A O no hydrogen 2.721 N/A VAL 173.A N GLY 185.A O no hydrogen 2.949 N/A MET 174.A N LEU 97.A O no hydrogen 2.866 N/A ILE 175.A N TRP 183.A O no hydrogen 2.738 N/A TYR 177.A N PHE 181.A O no hydrogen 2.821 N/A SER 178.A N PHE 181.A O no hydrogen 3.299 N/A SER 178.A OG THR 180.A OG1 no hydrogen 3.419 N/A THR 180.A N SER 178.A OG no hydrogen 3.094 N/A THR 180.A OG1 SER 178.A OG no hydrogen 3.419 N/A THR 182.A N ASN 56.A OD1 no hydrogen 2.860 N/A TRP 183.A N ILE 175.A O no hydrogen 2.985 N/A TRP 183.A NE1 GLN 362.A OE1 no hydrogen 2.794 N/A CYS 184.A N VAL 57.A O no hydrogen 2.685 N/A GLY 185.A N VAL 173.A O no hydrogen 2.906 N/A GLU 186.A N ASN 59.A O no hydrogen 2.921 N/A LEU 187.A N VAL 171.A O no hydrogen 2.718 N/A GLY 188.A N MET 61.A O no hydrogen 2.884 N/A ALA 189.A N ALA 169.A O no hydrogen 3.038 N/A ILE 190.A N VAL 63.A O no hydrogen 2.832 N/A SER 194.A N SER 191.A O no hydrogen 2.920 N/A SER 194.A OG SER 191.A O no hydrogen 3.281 N/A GLN 197.A N GLY 62.A O no hydrogen 2.785 N/A GLN 197.A NE2 ALA 195.A O no hydrogen 3.443 N/A SER 199.A OG ASN 59.A OD1 no hydrogen 2.676 N/A SER 199.A OG SER 201.A OG no hydrogen 2.395 N/A SER 201.A N SER 199.A O no hydrogen 2.722 N/A SER 201.A OG SER 199.A OG no hydrogen 2.395 N/A ALA 202.A N GLN 362.A O no hydrogen 3.014 N/A ARG 203.A NE GLU 366.A OE1 no hydrogen 2.950 N/A ARG 203.A NE GLU 366.A OE2 no hydrogen 3.204 N/A ARG 203.A NH2 GLU 366.A OE1 no hydrogen 3.065 N/A ARG 203.A NH2 GLU 366.A OE2 no hydrogen 3.291 N/A SER 204.A N ARG 364.A O no hydrogen 2.781 N/A VAL 206.A N GLU 366.A O no hydrogen 2.871 N/A ASN 209.A N ASP 370.A OD1 no hydrogen 2.795 N/A SER 210.A N ASP 370.A OD1 no hydrogen 3.328 N/A ARG 212.A N ASN 209.A O no hydrogen 2.792 N/A ARG 212.A NE ASP 222.A OD1 no hydrogen 3.163 N/A ARG 212.A NE ASP 222.A OD2 no hydrogen 3.163 N/A ARG 212.A NH2 ASP 222.A OD1 no hydrogen 3.054 N/A TYR 213.A N SER 210.A O no hydrogen 2.989 N/A SER 214.A N ALA 211.A O no hydrogen 3.467 N/A SER 214.A OG ALA 211.A O no hydrogen 2.775 N/A SER 216.A N SER 260.A OG no hydrogen 3.299 N/A LYS 217.A N THR 215.A OG1 no hydrogen 3.265 N/A CYS 219.A N SER 216.A O no hydrogen 3.435 N/A CYS 219.A SG SER 216.A O no hydrogen 3.961 N/A ASP 222.A N PHE 218.A O no hydrogen 3.107 N/A GLY 223.A N GLU 220.A O no hydrogen 3.120 N/A CYS 224.A N CYS 219.A O no hydrogen 2.810 N/A CYS 224.A SG ASP 222.A O no hydrogen 3.742 N/A THR 225.A N THR 228.A OG1 no hydrogen 3.098 N/A THR 225.A OG1 GLU 227.A OE1 no hydrogen 3.222 N/A GLU 227.A N THR 225.A OG1 no hydrogen 3.136 N/A THR 228.A OG1 GLY 223.A O no hydrogen 2.962 N/A THR 228.A OG1 THR 225.A O no hydrogen 3.267 N/A GLY 229.A N ALA 226.A O no hydrogen 3.125 N/A MET 230.A N THR 225.A O no hydrogen 2.729 N/A LYS 232.A N ASN 249.A OD1 no hydrogen 3.070 N/A SER 234.A N MET 248.A O no hydrogen 2.812 N/A LEU 236.A N ALA 246.A O no hydrogen 2.730 N/A THR 237.A N ALA 246.A O no hydrogen 3.476 N/A THR 237.A OG1 GLN 244.A O no hydrogen 3.351 N/A THR 237.A OG1 GLN 361.A OE1 no hydrogen 2.649 N/A GLN 244.A NE2 GLY 275.A O no hydrogen 3.276 N/A ALA 246.A N THR 237.A OG1 no hydrogen 2.808 N/A LYS 247.A N ASP 272.A O no hydrogen 2.947 N/A MET 248.A N SER 234.A O no hydrogen 2.745 N/A ASN 249.A N LEU 270.A O no hydrogen 3.113 N/A ASN 249.A ND2 MET 230.A O no hydrogen 2.912 N/A ASN 249.A ND2 ILE 269.A O no hydrogen 2.933 N/A THR 250.A N LYS 232.A O no hydrogen 3.182 N/A THR 250.A OG1 LYS 232.A O no hydrogen 3.113 N/A CYS 251.A N ASN 249.A OD1 no hydrogen 2.849 N/A CYS 253.A N THR 250.A O no hydrogen 3.209 N/A CYS 253.A SG VAL 206.A O no hydrogen 3.485 N/A CYS 253.A SG THR 250.A O no hydrogen 3.391 N/A TYR 254.A N CYS 251.A O no hydrogen 2.957 N/A TYR 255.A OH PRO 263.A O no hydrogen 2.907 N/A LYS 256.A N CYS 253.A O no hydrogen 2.872 N/A LYS 256.A NZ MET 348.A O no hydrogen 3.374 N/A LYS 256.A NZ PRO 349.A O no hydrogen 2.709 N/A LYS 256.A NZ LEU 351.A O no hydrogen 2.725 N/A TYR 257.A N CYS 253.A O no hydrogen 2.845 N/A TYR 257.A OH TYR 367.A O no hydrogen 2.598 N/A SER 258.A N TYR 254.A O no hydrogen 2.817 N/A VAL 259.A N SER 214.A O no hydrogen 2.955 N/A SER 260.A N SER 258.A OG no hydrogen 3.086 N/A HIS 267.A ND1 ASP 266.A OD2 no hydrogen 3.051 N/A LEU 268.A N VAL 343.A O no hydrogen 2.739 N/A LEU 270.A N VAL 341.A O no hydrogen 2.847 N/A ASP 272.A N LYS 247.A O no hydrogen 3.013 N/A LEU 273.A N LEU 339.A O no hydrogen 2.769 N/A ALA 274.A N GLN 245.A O no hydrogen 2.844 N/A GLY 275.A N ASN 337.A O no hydrogen 2.923 N/A LEU 276.A N ASN 337.A O no hydrogen 2.833 N/A ASP 277.A N ASN 337.A OD1 no hydrogen 2.816 N/A SER 278.A N GLY 275.A O no hydrogen 3.087 N/A SER 278.A OG GLY 275.A O no hydrogen 3.179 N/A LEU 279.A N GLY 275.A O no hydrogen 3.169 N/A LEU 279.A N LEU 276.A O no hydrogen 3.341 N/A VAL 283.A N MET 311.A O no hydrogen 2.936 N/A TYR 284.A N MET 357.A O no hydrogen 2.772 N/A TYR 284.A OH GLN 8.A O no hydrogen 2.526 N/A VAL 285.A N LEU 309.A O no hydrogen 3.023 N/A MET 286.A N SER 355.A O no hydrogen 2.932 N/A ALA 287.A N CYS 307.A O no hydrogen 2.826 N/A ALA 288.A N GLY 353.A O no hydrogen 2.630 N/A TYR 289.A N TYR 305.A O no hydrogen 2.931 N/A PHE 290.A N ASN 350.A O no hydrogen 2.878 N/A THR 293.A OG1 ASP 291.A OD1 no hydrogen 2.915 N/A VAL 298.A N ASN 296.A OD1 no hydrogen 2.996 N/A ARG 299.A N ASN 296.A O no hydrogen 2.877 N/A SER 301.A N ARG 299.A O no hydrogen 2.482 N/A LYS 303.A NZ ASP 92.A OD2 no hydrogen 2.815 N/A LEU 304.A N ASN 91.A OD1 no hydrogen 3.010 N/A TYR 305.A N TYR 289.A O no hydrogen 2.666 N/A HIS 306.A NE2 VAL 85.A O no hydrogen 2.738 N/A CYS 307.A N ALA 287.A O no hydrogen 3.060 N/A LEU 309.A N VAL 285.A O no hydrogen 2.775 N/A GLN 310.A NE2 SER 9.A OG no hydrogen 3.037 N/A MET 311.A N VAL 283.A O no hydrogen 2.857 N/A THR 312.A N THR 319.A O no hydrogen 2.785 N/A THR 312.A OG1 HIS 314.A NE2 no hydrogen 3.310 N/A HIS 314.A N VAL 317.A O no hydrogen 2.782 N/A VAL 317.A N HIS 314.A O no hydrogen 3.305 N/A TRP 318.A NE1 LEU 276.A O no hydrogen 3.068 N/A THR 319.A N THR 312.A O no hydrogen 3.041 N/A SER 320.A OG THR 321.A O no hydrogen 3.168 N/A THR 321.A N GLN 310.A O no hydrogen 2.988 N/A GLN 325.A NE2 GLU 324.A OE2 no hydrogen 3.453 N/A CYS 326.A N SER 323.A O no hydrogen 3.152 N/A ARG 329.A N ARG 342.A O no hydrogen 2.796 N/A VAL 331.A N GLN 340.A O no hydrogen 2.998 N/A GLY 333.A N VAL 338.A O no hydrogen 2.761 N/A ASN 337.A N SER 335.A OG no hydrogen 3.057 N/A VAL 338.A N SER 335.A O no hydrogen 3.334 N/A LEU 339.A N LEU 273.A O no hydrogen 2.831 N/A GLN 340.A N VAL 331.A O no hydrogen 2.884 N/A VAL 341.A N ALA 271.A O no hydrogen 2.807 N/A ARG 342.A N ARG 329.A O no hydrogen 2.671 N/A ARG 342.A NE GLN 340.A OE1 no hydrogen 3.163 N/A ARG 342.A NH2 GLN 340.A OE1 no hydrogen 3.083 N/A VAL 343.A N LEU 268.A O no hydrogen 3.084 N/A SER 347.A N ALA 344.A O no hydrogen 2.788 N/A SER 347.A OG ALA 344.A O no hydrogen 2.698 N/A MET 348.A N PRO 345.A O no hydrogen 3.019 N/A LEU 351.A N MET 348.A O no hydrogen 2.992 N/A VAL 352.A N ALA 288.A O no hydrogen 2.781 N/A GLY 353.A N ALA 288.A O no hydrogen 3.081 N/A VAL 354.A N LEU 365.A O no hydrogen 2.846 N/A SER 355.A N MET 286.A O no hydrogen 2.692 N/A SER 355.A OG PRO 83.A O no hydrogen 2.452 N/A LEU 356.A N TYR 363.A O no hydrogen 2.671 N/A MET 357.A N TYR 284.A O no hydrogen 2.815 N/A LEU 358.A N GLN 361.A O no hydrogen 2.969 N/A GLY 360.A N VAL 5.A O no hydrogen 2.845 N/A GLN 361.A N LEU 358.A O no hydrogen 3.151 N/A GLN 361.A NE2 GLN 244.A O no hydrogen 2.716 N/A GLN 362.A N LEU 200.A O no hydrogen 2.991 N/A GLN 362.A NE2 PRO 81.A O no hydrogen 2.767 N/A TYR 363.A N LEU 356.A O no hydrogen 2.733 N/A TYR 363.A OH GLN 361.A OE1 no hydrogen 2.559 N/A ARG 364.A N ALA 202.A O no hydrogen 2.865 N/A ARG 364.A NE GLU 366.A OE1 no hydrogen 2.845 N/A ARG 364.A NH1 PHE 82.A O no hydrogen 2.848 N/A ARG 364.A NH1 ASP 153.A OD1 no hydrogen 3.035 N/A ARG 364.A NH2 ASP 153.A OD1 no hydrogen 2.955 N/A ARG 364.A NH2 ASP 153.A OD2 no hydrogen 3.370 N/A ARG 364.A NH2 GLU 366.A OE1 no hydrogen 2.963 N/A LEU 365.A N VAL 354.A O no hydrogen 2.665 N/A GLU 366.A N SER 204.A O no hydrogen 2.939 N/A TYR 367.A N VAL 352.A O no hydrogen 2.851 N/A