Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2p4b_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 4.A N ALA 1.A O no hydrogen 2.634 N/A LEU 5.A N ALA 1.A O no hydrogen 3.037 N/A LEU 6.A N SER 2.A O no hydrogen 2.996 N/A GLN 7.A N GLY 3.A O no hydrogen 3.136 N/A GLN 8.A N ALA 4.A O no hydrogen 2.825 N/A MET 9.A N LEU 5.A O no hydrogen 2.748 N/A ASN 10.A N LEU 6.A O no hydrogen 3.178 N/A ASN 10.A ND2 THR 92.A O no hydrogen 3.007 N/A LEU 11.A N GLN 7.A O no hydrogen 3.416 N/A ALA 12.A N GLN 8.A O no hydrogen 2.988 N/A SER 13.A N MET 9.A O no hydrogen 3.177 N/A SER 13.A OG MET 9.A O no hydrogen 2.781 N/A GLN 14.A N LEU 11.A O no hydrogen 2.891 N/A SER 15.A N LEU 11.A O no hydrogen 2.699 N/A SER 15.A OG LEU 11.A O no hydrogen 2.686 N/A LEU 16.A N ALA 12.A O no hydrogen 2.976 N/A ASN 17.A ND2 ASN 166.A O no hydrogen 3.277 N/A ASN 17.A ND2 GLN 167.A O no hydrogen 3.684 N/A TYR 18.A N HIS 37.A O no hydrogen 2.924 N/A TYR 18.A OH SER 13.A O no hydrogen 2.663 N/A GLU 19.A N ASN 164.A O no hydrogen 2.856 N/A LEU 20.A N TYR 35.A O no hydrogen 2.793 N/A SER 21.A N ALA 162.A O no hydrogen 2.789 N/A PHE 22.A N LEU 33.A O no hydrogen 2.716 N/A ILE 23.A N ARG 159.A O no hydrogen 3.015 N/A SER 24.A N GLU 31.A O no hydrogen 3.031 N/A ILE 25.A N GLN 157.A O no hydrogen 2.768 N/A ASN 26.A N GLY 29.A O no hydrogen 3.311 N/A LYS 27.A NZ ARG 246.A O no hydrogen 3.454 N/A GLY 29.A N ASN 26.A O no hydrogen 3.263 N/A GLY 29.A N ASN 26.A OD1 no hydrogen 3.316 N/A GLU 31.A N SER 24.A O no hydrogen 2.889 N/A SER 32.A OG ASP 52.A OD1 no hydrogen 3.305 N/A LEU 33.A N PHE 22.A O no hydrogen 2.863 N/A ARG 34.A N LEU 49.A O no hydrogen 3.099 N/A ARG 34.A NH2 GLN 47.A OE1 no hydrogen 3.218 N/A TYR 35.A N LEU 20.A O no hydrogen 2.697 N/A ARG 36.A N GLN 47.A O no hydrogen 2.915 N/A ARG 36.A NE GLU 19.A OE2 no hydrogen 2.736 N/A ARG 36.A NH1 GLN 47.A OE1 no hydrogen 3.455 N/A ARG 36.A NH2 GLU 19.A OE2 no hydrogen 3.176 N/A HIS 37.A N TYR 18.A O no hydrogen 2.902 N/A ALA 38.A N LEU 45.A O no hydrogen 2.760 N/A ARG 39.A N ASN 17.A OD1 no hydrogen 3.056 N/A ARG 39.A NH2 ASN 42.A OD1 no hydrogen 2.637 N/A LEU 40.A N ARG 43.A O no hydrogen 2.957 N/A LEU 45.A N ALA 38.A O no hydrogen 2.779 N/A ALA 46.A N GLN 60.A O no hydrogen 2.950 N/A GLN 47.A N ARG 36.A O no hydrogen 2.854 N/A GLN 47.A NE2 GLU 57.A OE2 no hydrogen 2.705 N/A LEU 48.A N VAL 58.A O no hydrogen 2.845 N/A LEU 49.A N ARG 34.A O no hydrogen 2.950 N/A GLN 50.A N ARG 56.A O no hydrogen 3.015 N/A MET 51.A N SER 32.A O no hydrogen 3.139 N/A ARG 56.A N PRO 54.A O no hydrogen 2.904 N/A ARG 56.A NE GLU 69.A OE1 no hydrogen 2.674 N/A ARG 56.A NH2 GLU 69.A OE1 no hydrogen 3.560 N/A GLU 57.A N PHE 68.A O no hydrogen 2.837 N/A VAL 58.A N LEU 48.A O no hydrogen 2.993 N/A VAL 59.A N SER 66.A O no hydrogen 2.886 N/A GLN 60.A N ALA 46.A O no hydrogen 2.730 N/A GLN 60.A NE2 GLY 62.A O no hydrogen 3.168 N/A GLN 60.A NE2 ASP 80.A O no hydrogen 2.792 N/A ARG 61.A N GLU 64.A O no hydrogen 3.070 N/A ARG 61.A NH1 LEU 176.A O no hydrogen 3.490 N/A ARG 61.A NH1 ALA 179.A O no hydrogen 3.262 N/A GLY 62.A N PRO 44.A O no hydrogen 3.125 N/A GLU 64.A N ARG 61.A O no hydrogen 3.221 N/A ILE 65.A N LEU 77.A O no hydrogen 2.920 N/A SER 66.A N VAL 59.A O no hydrogen 2.958 N/A SER 66.A OG THR 76.A OG1 no hydrogen 2.696 N/A TYR 67.A N PHE 75.A O no hydrogen 2.999 N/A PHE 68.A N GLU 57.A O no hydrogen 2.790 N/A LEU 72.A N GLU 69.A O no hydrogen 3.299 N/A THR 76.A N PRO 183.A O no hydrogen 3.043 N/A THR 76.A OG1 SER 66.A OG no hydrogen 2.696 N/A THR 76.A OG1 PRO 182.A O no hydrogen 3.155 N/A LEU 77.A N ILE 65.A O no hydrogen 3.010 N/A ASN 78.A ND2 ASN 63.A O no hydrogen 3.166 N/A GLY 79.A N ASN 63.A O no hydrogen 3.364 N/A SER 85.A OG ILE 82.A O no hydrogen 2.680 N/A LEU 86.A N SER 85.A OG no hydrogen 2.524 N/A ILE 90.A N PRO 87.A O no hydrogen 2.782 N/A TYR 91.A N SER 88.A O no hydrogen 2.992 N/A THR 92.A N LEU 89.A O no hydrogen 3.126 N/A THR 92.A OG1 LEU 89.A O no hydrogen 3.222 N/A THR 92.A OG1 GLY 225.A O no hydrogen 3.568 N/A LYS 95.A N ASP 93.A OD1 no hydrogen 3.188 N/A ARG 96.A N ASP 93.A O no hydrogen 2.927 N/A ARG 96.A NH2 SER 200.A OG no hydrogen 2.792 N/A LEU 97.A N PHE 94.A O no hydrogen 3.076 N/A SER 98.A N PHE 94.A O no hydrogen 3.051 N/A SER 98.A OG LYS 95.A O no hydrogen 2.792 N/A TYR 100.A N LEU 97.A O no hydrogen 2.627 N/A TYR 101.A N LEU 97.A O no hydrogen 2.963 N/A TYR 101.A OH ASP 224.A OD2 no hydrogen 2.463 N/A ASP 102.A N VAL 122.A O no hydrogen 2.731 N/A ILE 104.A N ARG 120.A O no hydrogen 2.907 N/A VAL 106.A N VAL 118.A O no hydrogen 2.491 N/A THR 109.A N CYS 116.A O no hydrogen 3.185 N/A ARG 110.A NH2 ASP 113.A OD2 no hydrogen 2.459 N/A ILE 111.A N ARG 114.A O no hydrogen 2.858 N/A ARG 114.A N ILE 111.A O no hydrogen 2.870 N/A ARG 114.A NH2 ASP 136.A OD2 no hydrogen 3.058 N/A CYS 116.A N THR 109.A O no hydrogen 2.790 N/A CYS 116.A SG ARG 114.A O no hydrogen 3.756 N/A GLU 117.A N MET 135.A O no hydrogen 2.736 N/A VAL 118.A N GLY 107.A O no hydrogen 2.897 N/A ILE 119.A N VAL 133.A O no hydrogen 2.748 N/A ARG 120.A N ILE 104.A O no hydrogen 2.684 N/A VAL 121.A N TYR 131.A O no hydrogen 2.876 N/A VAL 122.A N ASP 102.A O no hydrogen 3.125 N/A ARG 124.A N TYR 100.A O no hydrogen 3.035 N/A ARG 124.A NH1 ASP 102.A OD1 no hydrogen 2.708 N/A ARG 124.A NH1 ASP 102.A OD2 no hydrogen 3.015 N/A GLY 126.A N ALA 123.A O no hydrogen 3.258 N/A THR 127.A N ASP 125.A OD1 no hydrogen 2.754 N/A THR 127.A OG1 ASP 125.A OD1 no hydrogen 2.500 N/A THR 127.A OG1 ASP 125.A OD2 no hydrogen 2.963 N/A ARG 128.A NE THR 127.A OG1 no hydrogen 3.255 N/A ARG 128.A NH1 GLN 197.A O no hydrogen 3.252 N/A ARG 128.A NH1 ASP 224.A OD2 no hydrogen 2.715 N/A ARG 128.A NH2 ASP 125.A OD2 no hydrogen 2.772 N/A ARG 128.A NH2 GLN 197.A O no hydrogen 2.988 N/A SER 130.A N LEU 148.A O no hydrogen 3.115 N/A TYR 131.A N VAL 121.A O no hydrogen 3.019 N/A ILE 132.A N ASP 146.A O no hydrogen 3.094 N/A VAL 133.A N ILE 119.A O no hydrogen 2.624 N/A TRP 134.A N ARG 144.A O no hydrogen 2.822 N/A MET 135.A N GLU 117.A O no hydrogen 2.796 N/A ASP 136.A N LEU 141.A O no hydrogen 2.916 N/A THR 137.A N LEU 115.A O no hydrogen 3.103 N/A THR 137.A OG1 LEU 115.A O no hydrogen 3.500 N/A SER 139.A N ASP 136.A OD2 no hydrogen 2.878 N/A SER 139.A OG ASP 136.A OD2 no hydrogen 2.427 N/A LYS 140.A N ASP 136.A O no hydrogen 2.604 N/A LYS 140.A NZ THR 137.A O no hydrogen 2.882 N/A LEU 141.A N SER 139.A OG no hydrogen 3.323 N/A MET 143.A N TRP 134.A O no hydrogen 2.777 N/A ARG 144.A N TRP 134.A O no hydrogen 3.320 N/A ARG 144.A NE ASP 146.A OD1 no hydrogen 2.923 N/A ARG 144.A NH2 ASP 146.A OD1 no hydrogen 3.511 N/A ARG 144.A NH2 ASP 146.A OD2 no hydrogen 2.605 N/A VAL 145.A N PHE 158.A O no hydrogen 2.886 N/A ASP 146.A N ILE 132.A O no hydrogen 3.051 N/A LEU 147.A N GLU 156.A O no hydrogen 2.925 N/A LEU 148.A N SER 130.A O no hydrogen 2.840 N/A ASP 149.A N GLU 153.A O no hydrogen 2.927 N/A ARG 150.A NH1 GLN 271.A OE1 no hydrogen 2.358 N/A GLY 152.A N ASP 149.A O no hydrogen 2.863 N/A GLU 153.A N ASP 149.A OD1 no hydrogen 2.802 N/A LEU 155.A N LEU 147.A O no hydrogen 2.778 N/A GLN 157.A N ILE 25.A O no hydrogen 2.890 N/A PHE 158.A N VAL 145.A O no hydrogen 2.895 N/A ARG 159.A N ILE 23.A O no hydrogen 3.096 N/A ARG 159.A NE GLN 157.A OE1 no hydrogen 2.744 N/A ARG 159.A NH2 GLN 157.A OE1 no hydrogen 2.828 N/A VAL 160.A N MET 143.A O no hydrogen 2.740 N/A ILE 161.A N SER 21.A O no hydrogen 2.794 N/A ALA 162.A N SER 21.A O no hydrogen 3.028 N/A ASN 164.A ND2 ASN 166.A OD1 no hydrogen 3.673 N/A ASN 166.A N ASN 17.A O no hydrogen 2.943 N/A ASN 166.A ND2 ASP 168.A O no hydrogen 3.204 N/A SER 170.A OG SER 172.A OG no hydrogen 3.224 N/A SER 172.A OG SER 170.A OG no hydrogen 3.224 N/A MET 173.A N SER 170.A OG no hydrogen 3.352 N/A GLN 174.A N SER 170.A O no hydrogen 3.232 N/A THR 175.A N SER 171.A O no hydrogen 2.840 N/A THR 175.A OG1 SER 171.A O no hydrogen 2.841 N/A LEU 176.A N SER 172.A O no hydrogen 2.998 N/A ALA 177.A N MET 173.A O no hydrogen 2.551 N/A LEU 181.A N ALA 179.A O no hydrogen 2.727 N/A TRP 190.A NE1 GLU 218.A OE1 no hydrogen 2.693 N/A THR 191.A N LYS 281.A O no hydrogen 3.170 N/A THR 193.A N ASN 279.A O no hydrogen 2.944 N/A PHE 199.A N PRO 196.A O no hydrogen 3.417 N/A SER 200.A N SER 223.A O no hydrogen 2.744 N/A SER 200.A OG SER 223.A O no hydrogen 3.352 N/A VAL 202.A N LEU 221.A O no hydrogen 2.717 N/A SER 203.A N LEU 221.A O no hydrogen 3.487 N/A SER 204.A OG GLU 201.A OE2 no hydrogen 2.599 N/A SER 204.A OG SER 203.A O no hydrogen 2.894 N/A SER 205.A N SER 219.A O no hydrogen 2.908 N/A ARG 206.A NE GLU 218.A OE2 no hydrogen 2.863 N/A ARG 206.A NH2 GLU 218.A OE2 no hydrogen 2.921 N/A ARG 207.A N ILE 217.A O no hydrogen 3.077 N/A LEU 209.A N MET 215.A O no hydrogen 2.508 N/A THR 211.A N LEU 209.A O no hydrogen 2.721 N/A THR 211.A OG1 ASP 213.A OD1 no hydrogen 3.020 N/A MET 215.A N THR 211.A OG1 no hydrogen 3.176 N/A ILE 217.A N ARG 207.A O no hydrogen 2.848 N/A GLU 218.A N VAL 233.A O no hydrogen 2.807 N/A SER 219.A N SER 205.A O no hydrogen 2.782 N/A ARG 220.A N VAL 231.A O no hydrogen 3.058 N/A ARG 220.A NH2 TRP 190.A O no hydrogen 3.061 N/A LEU 221.A N SER 203.A O no hydrogen 3.186 N/A TYR 222.A N PHE 229.A O no hydrogen 2.925 N/A SER 223.A N SER 200.A O no hydrogen 3.020 N/A SER 223.A OG PHE 227.A O no hydrogen 3.133 N/A ASP 224.A N PHE 227.A O no hydrogen 3.358 N/A GLY 225.A N SER 223.A OG no hydrogen 3.149 N/A LEU 226.A N ASP 224.A OD1 no hydrogen 2.902 N/A PHE 227.A N ASP 224.A OD1 no hydrogen 2.877 N/A SER 228.A N GLU 267.A OE1 no hydrogen 2.835 N/A PHE 229.A N TYR 222.A O no hydrogen 3.210 N/A SER 230.A N VAL 265.A O no hydrogen 2.724 N/A SER 230.A OG ASN 232.A OD1 no hydrogen 3.047 N/A SER 230.A OG VAL 265.A O no hydrogen 3.516 N/A VAL 231.A N ARG 220.A O no hydrogen 2.850 N/A ASN 232.A N THR 263.A O no hydrogen 2.729 N/A VAL 233.A N GLU 218.A O no hydrogen 2.837 N/A ASN 234.A N GLU 261.A O no hydrogen 3.241 N/A ASN 234.A ND2 ARG 235.A O no hydrogen 2.997 N/A ASN 234.A ND2 GLU 261.A OE2 no hydrogen 2.843 N/A ARG 235.A NH2 ASP 213.A OD2 no hydrogen 2.692 N/A ALA 236.A N ASN 259.A O no hydrogen 2.916 N/A THR 237.A N SER 240.A OG no hydrogen 2.892 N/A SER 240.A N THR 237.A O no hydrogen 2.907 N/A SER 240.A OG THR 237.A O no hydrogen 3.271 N/A SER 240.A OG GLU 261.A OE2 no hydrogen 2.924 N/A GLN 243.A N THR 254.A O no hydrogen 2.985 N/A GLN 243.A NE2 THR 241.A OG1 no hydrogen 2.921 N/A LEU 245.A N VAL 252.A O no hydrogen 3.054 N/A ARG 246.A NH1 TYR 129.A OH no hydrogen 3.137 N/A THR 247.A N ARG 250.A O no hydrogen 2.930 N/A ARG 249.A NE GLU 156.A OE2 no hydrogen 3.196 N/A ARG 249.A NH1 TYR 131.A OH no hydrogen 2.893 N/A ARG 249.A NH1 GLU 267.A OE2 no hydrogen 3.001 N/A ARG 249.A NH2 GLU 156.A OE2 no hydrogen 2.819 N/A ARG 250.A N THR 247.A O no hydrogen 3.112 N/A THR 251.A N GLY 266.A O no hydrogen 2.924 N/A THR 251.A OG1 LEU 268.A O no hydrogen 2.752 N/A VAL 252.A N LEU 245.A O no hydrogen 2.820 N/A SER 253.A N ILE 264.A O no hydrogen 2.865 N/A THR 254.A N GLN 243.A O no hydrogen 2.989 N/A SER 255.A N ILE 262.A O no hydrogen 2.786 N/A ARG 257.A N ALA 260.A O no hydrogen 3.124 N/A ARG 257.A NH1 GLU 278.A O no hydrogen 2.845 N/A ARG 257.A NH2 ILE 280.A O no hydrogen 2.978 N/A ALA 260.A N ARG 257.A O no hydrogen 2.684 N/A GLU 261.A N ASN 234.A O no hydrogen 3.026 N/A ILE 262.A N SER 255.A O no hydrogen 2.806 N/A THR 263.A N ASN 232.A O no hydrogen 2.755 N/A ILE 264.A N SER 253.A O no hydrogen 2.741 N/A VAL 265.A N SER 230.A O no hydrogen 3.022 N/A GLY 266.A N THR 251.A O no hydrogen 3.134 N/A GLU 267.A N SER 228.A O no hydrogen 2.933 N/A THR 272.A N PRO 269.A O no hydrogen 3.057 N/A THR 272.A OG1 THR 127.A O no hydrogen 2.486 N/A ALA 273.A N PRO 269.A O no hydrogen 3.227 N/A LYS 274.A N PRO 270.A O no hydrogen 3.059 N/A ARG 275.A N GLN 271.A O no hydrogen 3.103 N/A ILE 276.A N THR 272.A O no hydrogen 2.939 N/A ALA 277.A N ALA 273.A O no hydrogen 3.006 N/A GLU 278.A N LYS 274.A O no hydrogen 2.788 N/A ASN 279.A N ILE 276.A O no hydrogen 3.261 N/A ILE 280.A N ALA 277.A O no hydrogen 3.258 N/A LYS 281.A N THR 191.A O no hydrogen 3.093 N/A GLY 283.A N SER 189.A O no hydrogen 3.043 N/A