Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2p4m_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 1.A N TYR 34.A OH no hydrogen 3.498 N/A MET 8.A N GLY 31.A O no hydrogen 2.988 N/A THR 9.A N ASN 109.A O no hydrogen 3.111 N/A THR 9.A OG1 ASN 109.A O no hydrogen 3.471 N/A TYR 10.A N GLY 29.A O no hydrogen 2.856 N/A LYS 11.A N PHE 111.A O no hydrogen 2.927 N/A VAL 12.A N GLY 27.A O no hydrogen 3.005 N/A TYR 13.A N TYR 113.A O no hydrogen 2.803 N/A MET 14.A N VAL 25.A O no hydrogen 2.886 N/A SER 15.A N VAL 115.A O no hydrogen 3.071 N/A GLY 16.A N PHE 23.A O no hydrogen 3.129 N/A THR 17.A N PHE 117.A O no hydrogen 2.973 N/A VAL 18.A N HIS 21.A O no hydrogen 3.015 N/A ASN 19.A N GLY 119.A O no hydrogen 2.809 N/A ASN 19.A ND2 PHE 122.A O no hydrogen 2.855 N/A HIS 21.A N VAL 18.A O no hydrogen 2.901 N/A HIS 21.A NE2 GLY 47.A O no hydrogen 2.735 N/A TYR 22.A OH GLU 24.A OE2 no hydrogen 2.650 N/A PHE 23.A N GLY 16.A O no hydrogen 2.935 N/A GLU 24.A N LYS 46.A O no hydrogen 2.893 N/A VAL 25.A N MET 14.A O no hydrogen 2.715 N/A GLU 26.A N THR 43.A O no hydrogen 2.946 N/A GLY 27.A N VAL 12.A O no hydrogen 2.996 N/A ASP 28.A N LYS 41.A O no hydrogen 2.991 N/A GLY 29.A N TYR 10.A O no hydrogen 2.784 N/A LYS 30.A N THR 39.A O no hydrogen 2.923 N/A GLY 31.A N MET 8.A O no hydrogen 2.924 N/A LYS 32.A N GLU 37.A O no hydrogen 2.849 N/A TYR 34.A OH ILE 4.A O no hydrogen 2.716 N/A GLU 35.A N LYS 32.A O no hydrogen 2.868 N/A GLU 37.A N LYS 32.A O no hydrogen 3.511 N/A GLN 38.A N GLU 208.A O no hydrogen 3.075 N/A GLN 38.A NE2 SER 62.A OG no hydrogen 2.701 N/A THR 39.A N LYS 30.A O no hydrogen 2.908 N/A THR 39.A OG1 GLN 206.A O no hydrogen 3.039 N/A VAL 40.A N GLN 206.A O no hydrogen 3.019 N/A LYS 41.A N ASP 28.A O no hydrogen 3.029 N/A LEU 42.A N VAL 204.A O no hydrogen 2.658 N/A THR 43.A N GLU 26.A O no hydrogen 2.780 N/A VAL 44.A N THR 202.A O no hydrogen 2.914 N/A THR 45.A N GLU 24.A O no hydrogen 2.828 N/A THR 45.A OG1 GLU 24.A O no hydrogen 3.181 N/A LYS 46.A N GLU 24.A O no hydrogen 3.294 N/A ALA 53.A N VAL 128.A O no hydrogen 2.807 N/A TRP 54.A NE1 GLN 206.A OE1 no hydrogen 2.754 N/A LEU 57.A N TRP 54.A O no hydrogen 2.828 N/A SER 58.A N TRP 54.A O no hydrogen 3.254 N/A SER 58.A OG ASP 55.A O no hydrogen 2.937 N/A GLN 60.A N LEU 57.A O no hydrogen 2.982 N/A GLN 60.A NE2 ILE 56.A O no hydrogen 2.964 N/A CYS 61.A N SER 58.A O no hydrogen 3.421 N/A CYS 61.A SG LEU 57.A O no hydrogen 3.589 N/A SER 62.A OG TYR 113.A OH no hydrogen 2.727 N/A PHE 65.A N SER 62.A O no hydrogen 3.310 N/A THR 66.A OG1 ILE 63.A O no hydrogen 2.777 N/A LYS 67.A N SER 210.A O no hydrogen 2.828 N/A TYR 68.A OH HIS 186.A NE2 no hydrogen 2.784 N/A ILE 72.A N PRO 69.A O no hydrogen 3.185 N/A TYR 75.A OH GLY 148.A O no hydrogen 2.699 N/A TYR 75.A OH TYR 174.A O no hydrogen 3.192 N/A LYS 77.A N ASP 74.A OD1 no hydrogen 3.197 N/A LYS 77.A NZ PRO 33.A O no hydrogen 2.994 N/A LYS 77.A NZ PRO 64.A O no hydrogen 2.784 N/A LYS 77.A NZ THR 66.A O no hydrogen 2.749 N/A LYS 77.A NZ ASP 74.A OD2 no hydrogen 2.982 N/A GLN 78.A N ASP 74.A O no hydrogen 3.089 N/A GLN 78.A NE2 LYS 181.A O no hydrogen 3.002 N/A SER 79.A N VAL 76.A O no hydrogen 3.201 N/A SER 79.A OG VAL 76.A O no hydrogen 2.602 N/A PHE 80.A N LYS 77.A O no hydrogen 3.474 N/A GLU 82.A N GLU 82.A OE1 no hydrogen 2.787 N/A GLY 83.A N SER 79.A O no hydrogen 2.835 N/A PHE 84.A N SER 104.A O no hydrogen 3.385 N/A THR 85.A N LYS 175.A O no hydrogen 2.871 N/A TRP 86.A N ASN 102.A O no hydrogen 3.183 N/A GLU 87.A N THR 173.A O no hydrogen 2.956 N/A ARG 88.A N VAL 100.A O no hydrogen 2.792 N/A ARG 88.A NE THR 172.A OG1 no hydrogen 2.916 N/A ARG 88.A NH1 PRO 59.A O no hydrogen 2.724 N/A ARG 88.A NH1 GLN 60.A OE1 no hydrogen 3.032 N/A ILE 89.A N LYS 171.A O no hydrogen 2.873 N/A MET 90.A N CYS 98.A O no hydrogen 2.848 N/A ASN 91.A N GLU 169.A O no hydrogen 2.954 N/A PHE 92.A N ALA 96.A O no hydrogen 2.878 N/A GLU 93.A N LEU 167.A O no hydrogen 2.984 N/A GLY 95.A N PHE 92.A O no hydrogen 3.160 N/A VAL 97.A N LEU 120.A O no hydrogen 3.064 N/A CYS 98.A N MET 90.A O no hydrogen 2.957 N/A THR 99.A N SER 118.A O no hydrogen 2.858 N/A VAL 100.A N ARG 88.A O no hydrogen 2.947 N/A SER 101.A N LYS 116.A O no hydrogen 3.009 N/A ASN 102.A N TRP 86.A O no hydrogen 2.830 N/A ASN 102.A ND2 SER 104.A OG no hydrogen 2.680 N/A ASP 103.A N HIS 114.A O no hydrogen 2.853 N/A SER 104.A N PHE 84.A O no hydrogen 2.928 N/A SER 105.A N THR 112.A O no hydrogen 2.960 N/A SER 105.A OG THR 112.A O no hydrogen 3.392 N/A GLN 107.A N CYS 110.A O no hydrogen 2.781 N/A ASN 109.A ND2 GLN 7.A O no hydrogen 2.940 N/A CYS 110.A N GLN 107.A O no hydrogen 3.146 N/A CYS 110.A SG THR 9.A OG1 no hydrogen 3.743 N/A CYS 110.A SG PHE 111.A O no hydrogen 3.385 N/A PHE 111.A N THR 9.A O no hydrogen 2.966 N/A THR 112.A N SER 105.A O no hydrogen 2.851 N/A TYR 113.A N LYS 11.A O no hydrogen 2.855 N/A TYR 113.A OH SER 62.A OG no hydrogen 2.727 N/A HIS 114.A N ASP 103.A O no hydrogen 2.969 N/A VAL 115.A N TYR 13.A O no hydrogen 2.869 N/A LYS 116.A N SER 101.A O no hydrogen 2.870 N/A PHE 117.A N SER 15.A O no hydrogen 2.857 N/A SER 118.A N THR 99.A O no hydrogen 2.947 N/A GLY 119.A N THR 17.A O no hydrogen 2.832 N/A LEU 120.A N VAL 97.A O no hydrogen 3.038 N/A PHE 122.A N ASN 19.A OD1 no hydrogen 3.231 N/A GLY 126.A N PRO 123.A O no hydrogen 2.884 N/A GLN 130.A N GLY 126.A O no hydrogen 2.987 N/A GLN 130.A NE2 PRO 124.A O no hydrogen 2.882 N/A LYS 131.A N VAL 128.A O no hydrogen 3.251 N/A LYS 131.A NZ LEU 50.A O no hydrogen 2.842 N/A LYS 132.A N PRO 127.A O no hydrogen 2.816 N/A THR 133.A OG1 ASP 55.A OD2 no hydrogen 2.738 N/A GLN 134.A N LYS 159.A O no hydrogen 2.715 N/A GLY 135.A N ASP 55.A OD2 no hydrogen 2.839 N/A TRP 136.A NE1 ASP 55.A O no hydrogen 2.656 N/A GLU 137.A N ALA 157.A O no hydrogen 2.896 N/A SER 139.A N ARG 190.A O no hydrogen 2.899 N/A SER 140.A OG ASP 189.A OD1 no hydrogen 2.705 N/A GLU 141.A N VAL 188.A O no hydrogen 2.748 N/A ARG 142.A N ASN 153.A O no hydrogen 2.788 N/A ARG 142.A NH1 TYR 185.A OH no hydrogen 2.897 N/A LEU 143.A N HIS 186.A O no hydrogen 2.831 N/A PHE 144.A N ILE 151.A O no hydrogen 3.083 N/A ARG 146.A N MET 149.A O no hydrogen 2.929 N/A MET 149.A N ARG 146.A O no hydrogen 2.956 N/A LEU 150.A N TYR 174.A O no hydrogen 3.058 N/A ILE 151.A N PHE 144.A O no hydrogen 2.915 N/A GLY 152.A N THR 172.A O no hydrogen 2.671 N/A ASN 153.A N ARG 142.A O no hydrogen 2.809 N/A ASN 154.A N PHE 170.A O no hydrogen 2.982 N/A ASN 154.A ND2 SER 139.A OG no hydrogen 3.149 N/A MET 156.A N CYS 168.A O no hydrogen 2.816 N/A LEU 158.A N TYR 166.A O no hydrogen 2.771 N/A LYS 159.A N GLY 135.A O no hydrogen 2.926 N/A LEU 160.A N GLY 164.A O no hydrogen 3.105 N/A GLU 161.A N LYS 132.A O no hydrogen 2.910 N/A GLY 163.A N LEU 160.A O no hydrogen 2.917 N/A HIS 165.A NE2 GLU 137.A OE2 no hydrogen 2.705 N/A TYR 166.A N LEU 158.A O no hydrogen 2.773 N/A TYR 166.A OH ASP 94.A OD1 no hydrogen 2.684 N/A TYR 166.A OH ASP 94.A OD2 no hydrogen 3.252 N/A LEU 167.A N GLU 93.A OE2 no hydrogen 2.803 N/A CYS 168.A N MET 156.A O no hydrogen 3.047 N/A CYS 168.A SG GLU 169.A O no hydrogen 3.893 N/A GLU 169.A N ASN 91.A O no hydrogen 2.886 N/A PHE 170.A N ASN 154.A O no hydrogen 2.812 N/A LYS 171.A N ILE 89.A O no hydrogen 2.989 N/A THR 172.A N GLY 152.A O no hydrogen 2.830 N/A THR 173.A N GLU 87.A O no hydrogen 2.849 N/A TYR 174.A N LEU 150.A O no hydrogen 2.723 N/A TYR 174.A OH GLU 141.A OE2 no hydrogen 2.679 N/A LYS 175.A N THR 85.A O no hydrogen 2.796 N/A LYS 175.A NZ GLU 87.A OE1 no hydrogen 3.099 N/A LYS 175.A NZ GLU 87.A OE2 no hydrogen 2.762 N/A ALA 176.A N TYR 75.A OH no hydrogen 2.858 N/A LYS 177.A N GLY 83.A O no hydrogen 3.020 N/A LYS 177.A NZ ASP 103.A OD1 no hydrogen 3.490 N/A LYS 177.A NZ ASP 103.A OD2 no hydrogen 2.857 N/A LYS 178.A NZ PHE 80.A O no hydrogen 3.095 N/A LYS 178.A NZ GLU 82.A OE1 no hydrogen 3.184 N/A LYS 181.A N GLN 78.A OE1 no hydrogen 2.963 N/A HIS 186.A N LEU 143.A O no hydrogen 3.019 N/A HIS 186.A ND1 GLY 184.A O no hydrogen 2.810 N/A HIS 186.A NE2 TYR 68.A OH no hydrogen 2.784 N/A TYR 187.A N ARG 213.A O no hydrogen 2.946 N/A VAL 188.A N GLU 141.A O no hydrogen 2.995 N/A ASP 189.A N ILE 211.A O no hydrogen 2.973 N/A ARG 190.A N SER 139.A O no hydrogen 2.937 N/A ARG 190.A NH1 GLU 141.A OE1 no hydrogen 2.868 N/A ARG 190.A NH2 GLU 141.A OE1 no hydrogen 3.427 N/A LYS 191.A N ILE 209.A O no hydrogen 3.027 N/A LYS 191.A NZ ASP 193.A OD1 no hydrogen 2.921 N/A LYS 191.A NZ ASP 193.A OD2 no hydrogen 3.174 N/A ASP 193.A N CYS 207.A O no hydrogen 2.948 N/A THR 195.A N GLU 205.A O no hydrogen 2.886 N/A THR 195.A OG1 GLU 205.A O no hydrogen 3.486 N/A THR 195.A OG1 GLU 205.A OE1 no hydrogen 2.717 N/A ASN 196.A N GLU 205.A O no hydrogen 3.447 N/A HIS 197.A N ASN 196.A OD1 no hydrogen 2.860 N/A HIS 197.A ND1 ASN 198.A O no hydrogen 2.814 N/A ASN 198.A N SER 203.A O no hydrogen 3.078 N/A ASN 198.A ND2 THR 202.A OG1 no hydrogen 2.803 N/A TYR 201.A N ASN 198.A O no hydrogen 3.296 N/A THR 202.A OG1 ASP 200.A OD1 no hydrogen 2.716 N/A SER 203.A N ASN 198.A OD1 no hydrogen 2.959 N/A VAL 204.A N LEU 42.A O no hydrogen 2.991 N/A GLU 205.A N ASN 196.A O no hydrogen 2.772 N/A GLN 206.A N VAL 40.A O no hydrogen 2.867 N/A GLN 206.A NE2 SER 58.A O no hydrogen 3.124 N/A CYS 207.A N ASP 193.A O no hydrogen 2.803 N/A CYS 207.A SG GLN 38.A O no hydrogen 4.006 N/A GLU 208.A N GLN 38.A O no hydrogen 2.982 N/A ILE 209.A N LYS 191.A O no hydrogen 3.070 N/A SER 210.A N GLY 36.A O no hydrogen 2.802 N/A SER 210.A OG GLU 208.A OE2 no hydrogen 2.791 N/A ILE 211.A N ASP 189.A O no hydrogen 3.016 N/A ALA 212.A N LYS 67.A O no hydrogen 2.794 N/A ARG 213.A N TYR 187.A O no hydrogen 2.815 N/A ARG 213.A NE ASP 189.A OD2 no hydrogen 2.697 N/A ARG 213.A NH1 LYS 214.A O no hydrogen 3.288 N/A LYS 214.A NZ ASP 71.A OD2 no hydrogen 2.943 N/A