Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2px4_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 1.A NE GLU 9.A OE1 no hydrogen 3.229 N/A THR 2.A N GLU 5.A OE1 no hydrogen 3.024 N/A THR 2.A OG1 GLU 5.A OE1 no hydrogen 3.339 N/A THR 2.A OG1 TYR 180.A O no hydrogen 3.306 N/A GLU 5.A N THR 2.A OG1 no hydrogen 3.221 N/A GLN 6.A N THR 2.A O no hydrogen 3.221 N/A GLN 6.A NE2 ARG 1.A O no hydrogen 3.658 N/A TRP 7.A N LEU 3.A O no hydrogen 2.828 N/A TRP 7.A NE1 TYR 22.A OH no hydrogen 3.126 N/A LYS 8.A N GLY 4.A O no hydrogen 2.888 N/A LYS 8.A NZ SER 144.A O no hydrogen 2.713 N/A LYS 8.A NZ GLU 150.A OE1 no hydrogen 3.306 N/A LYS 8.A NZ GLU 150.A OE2 no hydrogen 3.073 N/A GLU 9.A N GLU 5.A O no hydrogen 3.091 N/A LYS 10.A N GLN 6.A O no hydrogen 3.057 N/A LEU 11.A N TRP 7.A O no hydrogen 2.809 N/A ASN 12.A N LYS 8.A O no hydrogen 2.955 N/A ASN 12.A ND2 PRO 145.A O no hydrogen 2.846 N/A ALA 13.A N GLU 9.A O no hydrogen 3.091 N/A ALA 13.A N LYS 10.A O no hydrogen 3.259 N/A MET 14.A N LEU 11.A O no hydrogen 3.253 N/A GLY 15.A N GLU 18.A OE2 no hydrogen 3.448 N/A PHE 19.A N GLY 15.A O no hydrogen 2.798 N/A PHE 20.A N LYS 16.A O no hydrogen 2.957 N/A SER 21.A N GLU 17.A O no hydrogen 2.974 N/A SER 21.A OG GLU 17.A O no hydrogen 3.446 N/A SER 21.A OG GLU 17.A OE2 no hydrogen 2.922 N/A TYR 22.A N GLU 18.A O no hydrogen 2.799 N/A TYR 22.A OH LEU 233.A O no hydrogen 2.754 N/A ARG 23.A N PHE 19.A O no hydrogen 2.966 N/A GLU 25.A N TYR 22.A O no hydrogen 3.092 N/A ALA 26.A N GLY 244.A O no hydrogen 2.960 N/A LEU 28.A N PRO 203.A O no hydrogen 2.959 N/A GLU 29.A N LYS 246.A O no hydrogen 2.706 N/A ASP 31.A N GLU 248.A O no hydrogen 3.484 N/A ARG 32.A NH1 PRO 47.A O no hydrogen 2.966 N/A ARG 32.A NH1 ASP 250.A OD2 no hydrogen 2.790 N/A ARG 32.A NH2 PRO 47.A O no hydrogen 3.083 N/A THR 33.A OG1 ASP 31.A OD2 no hydrogen 3.190 N/A ARG 36.A N ARG 32.A O no hydrogen 2.785 N/A ARG 37.A N THR 33.A O no hydrogen 3.090 N/A ALA 38.A N ALA 35.A O no hydrogen 3.130 N/A LYS 42.A NZ LEU 108.A O no hydrogen 2.834 N/A GLY 51.A N SER 49.A OG no hydrogen 3.100 N/A THR 52.A OG1 GLY 79.A O no hydrogen 2.896 N/A LEU 55.A N GLY 51.A O no hydrogen 3.117 N/A ARG 56.A N THR 52.A O no hydrogen 2.922 N/A ARG 56.A NH1 GLU 249.A O no hydrogen 3.517 N/A ARG 56.A NH2 GLU 249.A O no hydrogen 2.769 N/A TRP 57.A N ALA 53.A O no hydrogen 3.018 N/A LEU 58.A N LYS 54.A O no hydrogen 3.260 N/A VAL 59.A N LEU 55.A O no hydrogen 2.890 N/A GLU 60.A N ARG 56.A O no hydrogen 2.704 N/A ARG 61.A N LEU 58.A O no hydrogen 3.328 N/A ARG 61.A NH1 TRP 57.A O no hydrogen 3.020 N/A ARG 62.A N VAL 59.A O no hydrogen 2.881 N/A PHE 63.A N LEU 58.A O no hydrogen 2.953 N/A GLN 65.A N GLU 171.A OE1 no hydrogen 2.930 N/A ILE 67.A N THR 135.A OG1 no hydrogen 2.793 N/A GLY 68.A N ASN 89.A O no hydrogen 2.883 N/A LYS 69.A N ASP 134.A OD2 no hydrogen 2.920 N/A VAL 70.A N GLU 92.A O no hydrogen 2.768 N/A VAL 71.A N THR 135.A O no hydrogen 2.916 N/A ASP 72.A N ARG 94.A O no hydrogen 2.730 N/A LEU 73.A N LEU 137.A O no hydrogen 2.816 N/A CYS 75.A N TYR 96.A O no hydrogen 2.932 N/A CYS 75.A SG GLY 76.A O no hydrogen 3.756 N/A GLY 76.A N THR 97.A OG1 no hydrogen 3.017 N/A ARG 77.A NE VAL 48.A O no hydrogen 3.229 N/A ARG 77.A NH2 VAL 48.A O no hydrogen 3.316 N/A GLY 78.A N CYS 75.A O no hydrogen 2.848 N/A TRP 80.A NE1 GLY 51.A O no hydrogen 3.087 N/A SER 81.A OG ASP 72.A OD2 no hydrogen 2.668 N/A TYR 82.A N GLY 78.A O no hydrogen 2.962 N/A TYR 82.A OH MET 107.A O no hydrogen 3.295 N/A TYR 83.A N GLY 79.A O no hydrogen 3.372 N/A ALA 84.A N TRP 80.A O no hydrogen 2.912 N/A ALA 85.A N SER 81.A O no hydrogen 3.175 N/A THR 86.A N TYR 83.A O no hydrogen 3.052 N/A THR 86.A OG1 TYR 83.A O no hydrogen 2.694 N/A MET 87.A N ALA 84.A O no hydrogen 3.025 N/A VAL 90.A N MET 87.A O no hydrogen 3.259 N/A GLN 91.A N GLY 68.A O no hydrogen 2.923 N/A GLN 91.A NE2 GLY 261.A O no hydrogen 3.071 N/A GLU 92.A N GLY 68.A O no hydrogen 3.427 N/A VAL 93.A N ILE 116.A O no hydrogen 2.902 N/A ARG 94.A N VAL 70.A O no hydrogen 2.763 N/A GLY 95.A N THR 118.A O no hydrogen 2.869 N/A TYR 96.A N ASP 72.A O no hydrogen 2.924 N/A TYR 96.A OH GLU 131.A OE2 no hydrogen 3.029 N/A THR 97.A N LYS 120.A O no hydrogen 3.050 N/A GLY 100.A N GLU 105.A OE2 no hydrogen 2.696 N/A HIS 103.A N GLY 100.A O no hydrogen 3.126 N/A GLU 104.A N GLU 104.A OE1 no hydrogen 2.693 N/A MET 107.A N ARG 77.A O no hydrogen 2.987 N/A MET 109.A N TYR 82.A OH no hydrogen 2.889 N/A GLN 110.A N LYS 42.A O no hydrogen 2.989 N/A TYR 112.A N LEU 253.A O no hydrogen 2.956 N/A GLY 113.A N GLY 256.A O no hydrogen 3.020 N/A TRP 114.A N SER 111.A O no hydrogen 3.069 N/A ASN 115.A ND2 ARG 258.A O no hydrogen 2.854 N/A ILE 116.A N GLY 113.A O no hydrogen 3.063 N/A VAL 117.A N TRP 114.A O no hydrogen 3.143 N/A THR 118.A N VAL 93.A O no hydrogen 3.045 N/A THR 118.A OG1 VAL 93.A O no hydrogen 3.462 N/A LYS 120.A N GLY 95.A O no hydrogen 2.833 N/A SER 121.A OG GLU 105.A OE1 no hydrogen 2.623 N/A SER 121.A OG GLU 105.A OE2 no hydrogen 3.460 N/A GLY 122.A N LYS 98.A O no hydrogen 2.997 N/A VAL 123.A N THR 97.A O no hydrogen 3.008 N/A PHE 126.A N ASP 124.A OD1 no hydrogen 3.114 N/A TYR 127.A N ASP 124.A O no hydrogen 3.166 N/A LYS 128.A N VAL 125.A O no hydrogen 3.303 N/A ASP 134.A N LYS 69.A O no hydrogen 2.973 N/A THR 135.A N LYS 69.A O no hydrogen 3.132 N/A THR 135.A OG1 ILE 67.A O no hydrogen 2.841 N/A LEU 136.A N GLU 171.A O no hydrogen 2.907 N/A LEU 137.A N VAL 71.A O no hydrogen 2.791 N/A CYS 138.A N CYS 173.A O no hydrogen 2.941 N/A ASP 139.A N LEU 73.A O no hydrogen 3.215 N/A SER 144.A N GLU 150.A OE2 no hydrogen 2.713 N/A SER 146.A N SER 144.A OG no hydrogen 3.041 N/A SER 146.A OG GLU 148.A OE1 no hydrogen 3.166 N/A ILE 149.A N SER 146.A OG no hydrogen 3.227 N/A GLU 150.A N SER 146.A O no hydrogen 3.053 N/A GLU 151.A N ALA 147.A O no hydrogen 2.721 N/A GLN 152.A N GLU 148.A O no hydrogen 3.169 N/A ARG 153.A N ILE 149.A O no hydrogen 2.996 N/A ARG 153.A NH1 GLU 142.A O no hydrogen 2.829 N/A ARG 153.A NH1 SER 143.A O no hydrogen 3.141 N/A THR 154.A N GLU 150.A O no hydrogen 2.762 N/A THR 154.A OG1 GLU 150.A O no hydrogen 2.812 N/A LEU 155.A N GLU 151.A O no hydrogen 2.851 N/A ARG 156.A N GLN 152.A O no hydrogen 3.042 N/A ILE 157.A N ARG 153.A O no hydrogen 3.060 N/A LEU 158.A N THR 154.A O no hydrogen 2.961 N/A GLU 159.A N LEU 155.A O no hydrogen 2.955 N/A MET 160.A N ARG 156.A O no hydrogen 3.124 N/A VAL 161.A N ILE 157.A O no hydrogen 2.841 N/A SER 162.A N LEU 158.A O no hydrogen 3.095 N/A SER 162.A OG LEU 158.A O no hydrogen 2.658 N/A LEU 165.A N VAL 161.A O no hydrogen 2.959 N/A SER 166.A N SER 162.A O no hydrogen 3.014 N/A SER 166.A OG ASP 163.A O no hydrogen 2.739 N/A ARG 167.A N TRP 164.A O no hydrogen 3.117 N/A GLY 168.A N LEU 165.A O no hydrogen 3.082 N/A PHE 172.A N SER 216.A OG no hydrogen 3.079 N/A CYS 173.A N LEU 136.A O no hydrogen 3.013 N/A ILE 174.A N TRP 214.A O no hydrogen 2.864 N/A LYS 175.A N CYS 138.A O no hydrogen 2.778 N/A LYS 175.A NZ GLY 141.A O no hydrogen 3.476 N/A LYS 175.A NZ GLU 211.A OE1 no hydrogen 3.564 N/A ILE 176.A N MET 212.A O no hydrogen 2.757 N/A CYS 178.A N THR 154.A OG1 no hydrogen 3.209 N/A CYS 178.A SG ALA 147.A O no hydrogen 3.855 N/A ILE 185.A N MET 181.A O no hydrogen 2.967 N/A GLU 186.A N PRO 182.A O no hydrogen 2.982 N/A LYS 187.A N LYS 183.A O no hydrogen 3.189 N/A LEU 188.A N VAL 184.A O no hydrogen 2.877 N/A GLU 189.A N ILE 185.A O no hydrogen 2.964 N/A SER 190.A N GLU 186.A O no hydrogen 3.317 N/A SER 190.A OG GLU 186.A O no hydrogen 3.111 N/A LEU 191.A N LYS 187.A O no hydrogen 2.922 N/A GLN 192.A N LEU 188.A O no hydrogen 2.684 N/A GLN 192.A NE2 GLY 197.A O no hydrogen 3.139 N/A GLN 192.A NE2 GLY 220.A O no hydrogen 2.946 N/A ARG 193.A N GLU 189.A O no hydrogen 3.187 N/A ARG 194.A N SER 190.A O no hydrogen 2.914 N/A PHE 195.A N LEU 191.A O no hydrogen 2.720 N/A GLY 196.A N GLN 192.A O no hydrogen 2.769 N/A GLY 198.A N VAL 215.A O no hydrogen 2.885 N/A VAL 200.A N TYR 213.A O no hydrogen 2.811 N/A ARG 201.A NH1 ASN 209.A O no hydrogen 3.123 N/A ARG 201.A NH1 ASN 209.A OD1 no hydrogen 3.386 N/A ARG 201.A NH1 GLU 211.A O no hydrogen 2.788 N/A ARG 201.A NH2 ARG 206.A O no hydrogen 2.987 N/A ARG 201.A NH2 ASN 209.A O no hydrogen 3.089 N/A SER 205.A N VAL 202.A O no hydrogen 3.017 N/A SER 205.A OG VAL 202.A O no hydrogen 3.343 N/A SER 205.A OG GLU 211.A OE2 no hydrogen 2.627 N/A ASN 207.A N ARG 23.A O no hydrogen 2.853 N/A ASN 207.A ND2 TYR 22.A O no hydrogen 2.751 N/A ASN 207.A ND2 GLU 25.A O no hydrogen 2.764 N/A ASN 209.A N ARG 206.A O no hydrogen 3.235 N/A HIS 210.A ND1 HIS 210.A O no hydrogen 2.588 N/A HIS 210.A NE2 SER 230.A OG no hydrogen 2.645 N/A GLU 211.A N ASN 209.A OD1 no hydrogen 3.063 N/A MET 212.A N ILE 176.A O no hydrogen 3.106 N/A TYR 213.A N VAL 200.A O no hydrogen 2.814 N/A TYR 213.A OH ASP 139.A OD1 no hydrogen 2.796 N/A TRP 214.A N ILE 174.A O no hydrogen 2.797 N/A TRP 214.A NE1 GLY 196.A O no hydrogen 2.993 N/A VAL 215.A N GLY 198.A O no hydrogen 2.820 N/A SER 216.A N PHE 172.A O no hydrogen 3.123 N/A SER 216.A OG GLU 171.A OE1 no hydrogen 3.314 N/A SER 216.A OG PHE 172.A O no hydrogen 3.388 N/A GLY 217.A N PHE 63.A O no hydrogen 2.713 N/A ALA 218.A N VAL 215.A O no hydrogen 3.353 N/A ALA 225.A N ASN 221.A O no hydrogen 3.129 N/A VAL 226.A N ILE 222.A O no hydrogen 2.939 N/A ASN 227.A N VAL 223.A O no hydrogen 2.907 N/A MET 228.A N HIS 224.A O no hydrogen 2.880 N/A THR 229.A N ALA 225.A O no hydrogen 3.179 N/A THR 229.A OG1 ALA 225.A O no hydrogen 3.226 N/A SER 230.A N VAL 226.A O no hydrogen 2.964 N/A SER 230.A OG HIS 210.A NE2 no hydrogen 2.645 N/A SER 230.A OG VAL 226.A O no hydrogen 3.197 N/A GLN 231.A N ASN 227.A O no hydrogen 3.046 N/A VAL 232.A N MET 228.A O no hydrogen 3.078 N/A LEU 233.A N THR 229.A O no hydrogen 2.984 N/A ILE 234.A N SER 230.A O no hydrogen 2.883 N/A GLY 235.A N GLN 231.A O no hydrogen 2.813 N/A ARG 236.A N VAL 232.A O no hydrogen 3.125 N/A ARG 236.A N LEU 233.A O no hydrogen 3.156 N/A ARG 236.A NH1 ASN 207.A OD1 no hydrogen 2.945 N/A MET 237.A N ILE 234.A O no hydrogen 3.087 N/A LYS 243.A N GLU 25.A OE2 no hydrogen 2.952 N/A GLY 244.A N GLU 25.A OE1 no hydrogen 2.939 N/A LYS 246.A N ILE 27.A O no hydrogen 2.822 N/A LYS 246.A NZ GLY 244.A O no hydrogen 2.795 N/A GLU 248.A N GLU 29.A O no hydrogen 2.942 N/A VAL 251.A N ASP 250.A OD1 no hydrogen 2.774 N/A LEU 253.A N GLY 45.A O no hydrogen 3.072 N/A GLY 256.A N GLN 110.A O no hydrogen 3.127 N/A ARG 258.A N ASN 115.A OD1 no hydrogen 2.801 N/A ARG 258.A NE ALA 259.A O no hydrogen 2.930 N/A ARG 258.A NH1 ALA 85.A O no hydrogen 2.871 N/A ARG 258.A NH1 MET 87.A O no hydrogen 2.854 N/A ARG 258.A NH2 MET 87.A O no hydrogen 3.504 N/A ARG 258.A NH2 LYS 88.A O no hydrogen 3.107 N/A