Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2q7d_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLN 10.A N HIS 6.A O no hydrogen 2.742 N/A THR 11.A N HIS 8.A O no hydrogen 3.084 N/A THR 11.A OG1 HIS 8.A O no hydrogen 2.585 N/A PHE 12.A N MET 9.A O no hydrogen 3.270 N/A LEU 13.A N GLN 10.A O no hydrogen 3.240 N/A GLY 15.A N GLY 43.A O no hydrogen 2.694 N/A LYS 16.A N LEU 13.A O no hydrogen 3.026 N/A LYS 16.A NZ.A PHE 12.A O no hydrogen 2.789 N/A ARG 17.A N ASP 62.A OD2 no hydrogen 2.777 N/A ARG 17.A NE GLU 45.A OE1 no hydrogen 2.834 N/A ARG 17.A NH1 GLN 58.A O no hydrogen 2.984 N/A ARG 17.A NH1 PRO 60.A O no hydrogen 2.908 N/A VAL 18.A N GLU 45.A O no hydrogen 2.726 N/A GLY 19.A N VAL 63.A O no hydrogen 2.859 N/A TYR 20.A N VAL 47.A O no hydrogen 2.924 N/A TRP 21.A N ILE 65.A O no hydrogen 2.931 N/A LYS 26.A N SER 23.A OG no hydrogen 2.961 N/A LYS 26.A NZ PHE 301.A O no hydrogen 2.983 N/A LYS 26.A NZ PRO 302.A O no hydrogen 2.911 N/A ILE 27.A N SER 23.A O no hydrogen 2.917 N/A LYS 28.A N GLU 24.A O no hydrogen 3.046 N/A LYS 29.A N LYS 25.A O no hydrogen 2.937 N/A LEU 30.A N LYS 26.A O no hydrogen 2.924 N/A ASN 31.A N LYS 28.A O no hydrogen 2.972 N/A PHE 32.A N ILE 27.A O no hydrogen 2.994 N/A ALA 34.A N ASN 31.A O no hydrogen 3.088 N/A ALA 36.A N PHE 32.A O no hydrogen 3.057 N/A GLU 37.A N GLN 33.A O no hydrogen 2.901 N/A LEU 38.A N ALA 34.A O no hydrogen 3.187 N/A CYS 39.A N PHE 35.A O no hydrogen 3.068 N/A CYS 39.A SG PHE 35.A O no hydrogen 3.636 N/A ARG 40.A N ALA 36.A O no hydrogen 3.147 N/A ARG 40.A NE.B GLU 37.A OE2 no hydrogen 3.090 N/A ARG 40.A NH2.A VAL 46.A O no hydrogen 2.990 N/A ARG 40.A NH2.B GLU 37.A OE2 no hydrogen 2.799 N/A LYS 41.A N GLU 37.A O no hydrogen 3.194 N/A ARG 42.A N CYS 39.A O no hydrogen 3.007 N/A GLY 43.A N ARG 40.A O no hydrogen 2.809 N/A MET 44.A N CYS 39.A O no hydrogen 3.001 N/A GLU 45.A N LYS 16.A O no hydrogen 2.769 N/A VAL 47.A N VAL 18.A O no hydrogen 2.871 N/A GLN 48.A NE2 GLU 24.A OE2.A no hydrogen 2.973 N/A LEU 49.A N TYR 20.A O no hydrogen 2.760 N/A ASN 50.A N GLN 58.A OE1 no hydrogen 2.884 N/A SER 52.A N ASN 50.A OD1 no hydrogen 2.920 N/A ARG 53.A N ASN 50.A O no hydrogen 3.184 N/A GLN 58.A N ILE 55.A O no hydrogen 2.839 N/A GLN 58.A NE2 ASN 50.A O no hydrogen 2.849 N/A GLN 58.A NE2 PRO 54.A O no hydrogen 2.951 N/A GLY 59.A N ILE 55.A O no hydrogen 3.158 N/A GLY 59.A N GLU 56.A O no hydrogen 2.994 N/A ASP 62.A N ARG 17.A O no hydrogen 2.740 N/A VAL 63.A N ARG 17.A O no hydrogen 3.192 N/A ILE 64.A N ILE 100.A O no hydrogen 2.719 N/A ILE 65.A N GLY 19.A O no hydrogen 2.882 N/A HIS 66.A N LEU 102.A O no hydrogen 3.016 N/A HIS 66.A NE2 ASP 103.A O no hydrogen 2.769 N/A LYS 67.A N TRP 21.A O no hydrogen 2.943 N/A LYS 67.A NZ HIS 170.A NE2 no hydrogen 3.408 N/A LYS 67.A NZ ALA 300.A O no hydrogen 2.916 N/A LYS 67.A NZ PHE 301.A O no hydrogen 2.837 N/A LEU 68.A N HIS 66.A ND1 no hydrogen 2.901 N/A ILE 72.A N LEU 68.A O no hydrogen 2.840 N/A LEU 73.A N THR 69.A O no hydrogen 2.909 N/A GLU 74.A N ASP 70.A O no hydrogen 2.843 N/A ALA 75.A N VAL 71.A O no hydrogen 2.825 N/A ASP 76.A N ILE 72.A O no hydrogen 2.836 N/A GLN 77.A N LEU 73.A O no hydrogen 3.223 N/A GLN 77.A N GLU 74.A O no hydrogen 2.888 N/A ASN 78.A N ALA 75.A O no hydrogen 2.895 N/A ASP 79.A N GLU 74.A O no hydrogen 3.076 N/A SER 82.A N ASP 79.A OD2 no hydrogen 2.972 N/A SER 82.A OG ASP 79.A OD2 no hydrogen 2.842 N/A LEU 83.A N ASP 79.A O no hydrogen 2.863 N/A GLU 84.A N SER 80.A O no hydrogen 3.055 N/A LEU 85.A N GLN 81.A O no hydrogen 3.010 N/A VAL 86.A N SER 82.A O no hydrogen 2.966 N/A HIS 87.A N LEU 83.A O no hydrogen 2.814 N/A ARG 88.A N GLU 84.A O no hydrogen 2.988 N/A ARG 88.A NH1 LEU 51.A O no hydrogen 2.720 N/A PHE 89.A N LEU 85.A O no hydrogen 2.976 N/A GLN 90.A N VAL 86.A O no hydrogen 2.724 N/A GLN 90.A NE2 GLN 90.A O no hydrogen 3.483 N/A GLN 90.A NE2 ASP 94.A OD1 no hydrogen 2.831 N/A GLU 91.A N HIS 87.A O no hydrogen 2.760 N/A TYR 92.A N ARG 88.A O no hydrogen 2.992 N/A ILE 93.A N PHE 89.A O no hydrogen 2.949 N/A ASP 94.A N GLN 90.A O no hydrogen 2.884 N/A ALA 95.A N GLU 91.A O no hydrogen 3.099 N/A HIS 96.A N ILE 93.A O no hydrogen 3.028 N/A HIS 96.A ND1 GLU 98.A OE1 no hydrogen 3.128 N/A HIS 96.A NE2 GLU 56.A OE2 no hydrogen 2.371 N/A GLU 98.A N GLU 98.A OE2 no hydrogen 2.706 N/A THR 99.A N HIS 96.A O no hydrogen 2.946 N/A THR 99.A OG1 LEU 61.A O no hydrogen 2.743 N/A ILE 100.A N ASP 62.A O no hydrogen 2.941 N/A LEU 102.A N ILE 64.A O no hydrogen 2.661 N/A ILE 108.A N PRO 104.A O no hydrogen 3.005 N/A ARG 109.A N LEU 105.A O no hydrogen 2.898 N/A ARG 109.A NH1 ASP 76.A OD1 no hydrogen 3.528 N/A THR 110.A N PRO 106.A O no hydrogen 3.363 N/A THR 110.A OG1 ALA 107.A O no hydrogen 2.563 N/A LEU 111.A N ILE 108.A O no hydrogen 2.895 N/A LEU 112.A N ARG 109.A O no hydrogen 3.103 N/A ARG 114.A N ARG 167.A O no hydrogen 2.785 N/A ARG 114.A NH1 THR 166.A O no hydrogen 2.926 N/A ARG 114.A NH1 SER 174.A O no hydrogen 3.137 N/A ARG 114.A NH2 SER 174.A O no hydrogen 3.093 N/A LYS 116.A N ASP 113.A OD1 no hydrogen 2.813 N/A SER 117.A N ASP 113.A O no hydrogen 2.994 N/A SER 117.A OG.A THR 110.A O no hydrogen 2.462 N/A SER 117.A OG.A ASP 113.A O no hydrogen 3.001 N/A SER 117.A OG.B ASP 113.A O no hydrogen 3.260 N/A SER 117.A OG.B ARG 114.A O no hydrogen 2.820 N/A TYR 118.A N ARG 114.A O no hydrogen 2.756 N/A TYR 118.A OH ILE 296.A O no hydrogen 3.036 N/A GLU 119.A N SER 115.A O no hydrogen 2.873 N/A LEU 120.A N LYS 116.A O no hydrogen 2.949 N/A ILE 121.A N SER 117.A O no hydrogen 2.916 N/A ARG 122.A N TYR 118.A O no hydrogen 2.889 N/A ARG 122.A NE GLU 119.A OE1 no hydrogen 2.855 N/A ARG 122.A NE GLU 119.A OE2 no hydrogen 3.345 N/A ARG 122.A NH2 GLU 119.A OE2 no hydrogen 2.682 N/A LYS 123.A N GLU 119.A O no hydrogen 2.881 N/A ILE 124.A N LEU 120.A O no hydrogen 2.866 N/A GLU 125.A N ILE 121.A O no hydrogen 2.791 N/A ALA 126.A N ARG 122.A O no hydrogen 2.916 N/A TYR 127.A N LYS 123.A O no hydrogen 2.982 N/A TYR 127.A OH VAL 335.A O no hydrogen 2.526 N/A MET 128.A N ILE 124.A O no hydrogen 2.975 N/A GLU 129.A N GLU 125.A O no hydrogen 2.886 N/A ARG 132.A N ASP 130.A OD1 no hydrogen 2.820 N/A ARG 132.A NE ASP 130.A OD1 no hydrogen 3.014 N/A ARG 132.A NE ASP 130.A OD2 no hydrogen 3.440 N/A ARG 132.A NH1 GLU 262.A OE1 no hydrogen 2.995 N/A ARG 132.A NH2 ASP 130.A OD2 no hydrogen 2.840 N/A ARG 132.A NH2 GLU 262.A OE2 no hydrogen 3.044 N/A ILE 133.A N ASP 130.A O no hydrogen 3.095 N/A CYS 134.A N HIS 293.A O no hydrogen 2.898 N/A CYS 134.A SG.A HIS 293.A O no hydrogen 3.890 N/A MET 139.A N VAL 193.A O no hydrogen 2.902 N/A LEU 141.A N CYS 191.A O no hydrogen 2.809 N/A CYS 145.A SG LEU 186.A O no hydrogen 2.491 N/A CYS 145.A SG ALA 188.A O no hydrogen 3.823 N/A GLY 146.A N THR 149.A OG1 no hydrogen 2.840 N/A THR 149.A N GLY 146.A O no hydrogen 3.283 N/A THR 149.A OG1 GLY 146.A O no hydrogen 3.341 N/A LEU 152.A N ASP 148.A O no hydrogen 3.036 N/A LEU 153.A N THR 149.A O no hydrogen 2.889 N/A GLU 154.A N MET 150.A O no hydrogen 2.978 N/A LYS 155.A N ARG 151.A O no hydrogen 2.990 N/A ASN 156.A N LEU 152.A O no hydrogen 3.347 N/A ASN 156.A N LEU 153.A O no hydrogen 3.025 N/A ASN 156.A ND2 LEU 152.A O no hydrogen 2.845 N/A GLY 157.A N GLU 154.A O no hydrogen 3.071 N/A LEU 158.A N LEU 153.A O no hydrogen 3.008 N/A THR 159.A N ASN 195.A OD1 no hydrogen 2.814 N/A PHE 162.A N VAL 180.A O no hydrogen 3.038 N/A ILE 163.A N GLN 194.A O no hydrogen 2.797 N/A CYS 164.A N ALA 178.A O no hydrogen 2.709 N/A LYS 165.A N VAL 192.A O no hydrogen 2.810 N/A LYS 165.A NZ TYR 118.A OH no hydrogen 2.958 N/A LYS 165.A NZ GLN 194.A OE1 no hydrogen 2.941 N/A THR 166.A OG1 VAL 168.A O no hydrogen 2.664 N/A THR 166.A OG1 SER 174.A O no hydrogen 3.383 N/A ALA 169.A N LEU 112.A O no hydrogen 2.858 N/A HIS 170.A ND1 ASP 70.A OD1 no hydrogen 2.576 N/A SER 174.A OG GLY 171.A O no hydrogen 2.769 N/A HIS 175.A ND1 SER 234.A OG no hydrogen 3.070 N/A MET 177.A N PHE 232.A O no hydrogen 2.852 N/A ALA 178.A N CYS 164.A O no hydrogen 3.044 N/A ILE 179.A N ILE 230.A O no hydrogen 2.691 N/A VAL 180.A N PHE 162.A O no hydrogen 2.852 N/A ASN 182.A ND2 SER 225.A O no hydrogen 2.550 N/A ASN 182.A ND2 ARG 227.A O no hydrogen 3.032 N/A GLY 185.A N ASN 182.A O no hydrogen 2.883 N/A GLY 185.A N ASN 182.A OD1 no hydrogen 2.945 N/A LEU 186.A N GLN 183.A O no hydrogen 3.117 N/A ASN 187.A ND2 GLU 184.A O no hydrogen 3.427 N/A CYS 191.A N LEU 141.A O no hydrogen 2.996 N/A VAL 192.A N LYS 165.A O no hydrogen 2.746 N/A VAL 193.A N MET 139.A O no hydrogen 2.753 N/A GLN 194.A N ILE 163.A O no hydrogen 2.936 N/A ASN 195.A N PRO 137.A O no hydrogen 2.910 N/A ASN 195.A ND2 GLY 157.A O no hydrogen 3.057 N/A PHE 196.A N PRO 161.A O no hydrogen 3.020 N/A ASN 198.A ND2 PHE 224.A O no hydrogen 3.496 N/A HIS 199.A ND1 ILE 197.A O no hydrogen 2.764 N/A HIS 199.A NE2 SER 220.A OG no hydrogen 2.669 N/A ASN 200.A N ASN 223.A OD1 no hydrogen 2.811 N/A ASN 200.A ND2 GLU 253.A O no hydrogen 2.877 N/A LEU 203.A N ARG 218.A O no hydrogen 3.034 N/A TYR 204.A N ILE 284.A O no hydrogen 2.758 N/A LYS 205.A N VAL 216.A O no hydrogen 2.856 N/A LYS 205.A NZ ASP 283.A OD1 no hydrogen 2.804 N/A LYS 205.A NZ ASP 283.A OD2 no hydrogen 3.381 N/A VAL 206.A N ILE 282.A O no hydrogen 2.764 N/A PHE 207.A N THR 214.A O no hydrogen 2.743 N/A VAL 208.A N PHE 280.A O no hydrogen 2.762 N/A VAL 209.A N SER 212.A O no hydrogen 2.792 N/A GLY 210.A N SER 278.A O no hydrogen 2.734 N/A SER 212.A N VAL 209.A O no hydrogen 3.204 N/A SER 212.A OG.B VAL 209.A O no hydrogen 3.486 N/A TYR 213.A OH ASP 261.A OD1 no hydrogen 2.583 N/A THR 214.A N PHE 207.A O no hydrogen 2.882 N/A VAL 216.A N LYS 205.A O no hydrogen 2.772 N/A ARG 218.A N LEU 203.A O no hydrogen 2.839 N/A ARG 218.A NH1 SER 238.A O no hydrogen 2.860 N/A ARG 218.A NH2 GLU 305.A O no hydrogen 2.911 N/A SER 220.A OG HIS 199.A NE2 no hydrogen 2.669 N/A LYS 222.A N LEU 246.A O no hydrogen 2.821 N/A LYS 222.A NZ ASP 250.A OD1 no hydrogen 2.882 N/A LYS 222.A NZ ASP 250.A OD2 no hydrogen 2.746 N/A ASN 223.A ND2 ASN 200.A OD1 no hydrogen 2.956 N/A ASN 223.A ND2 GLU 253.A OE1 no hydrogen 3.016 N/A SER 229.A OG GLY 185.A O no hydrogen 3.025 N/A ILE 230.A N ILE 179.A O no hydrogen 2.938 N/A PHE 232.A N MET 177.A O no hydrogen 3.019 N/A ASN 233.A ND2 GLU 176.A OE2 no hydrogen 3.050 N/A SER 234.A N HIS 175.A O no hydrogen 2.708 N/A SER 234.A OG HIS 175.A O no hydrogen 3.451 N/A HIS 235.A N ASN 233.A OD1 no hydrogen 2.825 N/A ASN 236.A N ASN 233.A O no hydrogen 2.949 N/A VAL 237.A N SER 234.A O no hydrogen 3.285 N/A SER 238.A OG PRO 219.A O no hydrogen 2.683 N/A LYS 239.A N SER 242.A OG no hydrogen 2.910 N/A SER 242.A N LYS 239.A O no hydrogen 3.030 N/A SER 242.A OG LYS 239.A O no hydrogen 3.310 N/A LEU 246.A N SER 244.A OG no hydrogen 3.049 N/A THR 247.A N SER 244.A O no hydrogen 3.012 N/A THR 247.A OG1 SER 244.A O no hydrogen 3.211 N/A GLU 248.A N VAL 245.A O no hydrogen 3.437 N/A LYS 251.A NZ GLU 253.A OE2 no hydrogen 2.706 N/A GLU 253.A N ASN 200.A OD1 no hydrogen 2.988 N/A VAL 255.A N ASN 288.A O no hydrogen 2.771 N/A SER 260.A N HIS 293.A NE2 no hydrogen 2.881 N/A VAL 263.A N SER 260.A OG no hydrogen 3.171 N/A ILE 264.A N SER 260.A O no hydrogen 2.918 N/A ARG 265.A N ASP 261.A O no hydrogen 2.783 N/A GLU 266.A N GLU 262.A O no hydrogen 3.089 N/A LEU 267.A N VAL 263.A O no hydrogen 2.972 N/A SER 268.A N ILE 264.A O no hydrogen 2.800 N/A ARG 269.A N ARG 265.A O no hydrogen 2.943 N/A ALA 270.A N GLU 266.A O no hydrogen 2.933 N/A LEU 271.A N LEU 267.A O no hydrogen 2.837 N/A ARG 272.A N SER 268.A O no hydrogen 2.872 N/A ARG 272.A NE SER 268.A O no hydrogen 3.242 N/A ARG 272.A NE SER 268.A OG no hydrogen 2.827 N/A ARG 272.A NH2 SER 268.A OG no hydrogen 3.301 N/A GLN 273.A N ARG 269.A O no hydrogen 2.812 N/A ALA 274.A N ALA 270.A O no hydrogen 2.883 N/A LEU 275.A N LEU 271.A O no hydrogen 2.901 N/A GLY 276.A N ARG 272.A O no hydrogen 2.893 N/A SER 278.A N ASP 103.A OD2 no hydrogen 2.835 N/A SER 278.A OG ASP 103.A OD1 no hydrogen 2.866 N/A SER 278.A OG HIS 317.A NE2 no hydrogen 3.153 N/A LEU 279.A N ASP 103.A OD2 no hydrogen 3.019 N/A PHE 280.A N VAL 208.A O no hydrogen 3.247 N/A GLY 281.A N ASN 299.A O no hydrogen 2.838 N/A ILE 282.A N VAL 206.A O no hydrogen 2.910 N/A ASP 283.A N ASP 297.A O no hydrogen 2.872 N/A ILE 284.A N TYR 204.A O no hydrogen 2.853 N/A ILE 285.A N ALA 294.A O no hydrogen 2.943 N/A ASN 287.A N GLN 292.A O no hydrogen 2.869 N/A ASN 288.A N ASN 198.A O no hydrogen 2.893 N/A ASN 288.A ND2 GLU 253.A O no hydrogen 3.011 N/A GLN 289.A N ASN 287.A OD1 no hydrogen 2.756 N/A THR 290.A N ASN 287.A OD1 no hydrogen 3.221 N/A THR 290.A OG1 GLN 292.A OE1 no hydrogen 3.059 N/A GLY 291.A N ASN 287.A O no hydrogen 2.778 N/A GLN 292.A N THR 290.A OG1 no hydrogen 3.064 N/A GLN 292.A NE2 ASP 131.A O no hydrogen 2.901 N/A HIS 293.A N ARG 132.A O no hydrogen 2.648 N/A HIS 293.A ND1 ARG 132.A O no hydrogen 2.865 N/A ALA 294.A N ILE 285.A O no hydrogen 2.864 N/A ILE 296.A N ASP 283.A O no hydrogen 2.928 N/A ASN 299.A N GLY 281.A O no hydrogen 2.855 N/A ASN 299.A ND2 ASP 297.A OD1 no hydrogen 3.301 N/A ASN 299.A ND2 ASP 297.A OD2 no hydrogen 3.438 N/A PHE 301.A N LEU 279.A O no hydrogen 2.717 N/A TYR 304.A OH VAL 208.A O no hydrogen 2.675 N/A VAL 307.A N TYR 304.A O no hydrogen 2.954 N/A PHE 310.A N VAL 307.A O no hydrogen 3.173 N/A ASP 313.A N GLU 309.A O no hydrogen 2.851 N/A LEU 314.A N PHE 310.A O no hydrogen 2.778 N/A LEU 315.A N PHE 311.A O no hydrogen 2.959 N/A ASN 316.A N THR 312.A O no hydrogen 2.859 N/A HIS 317.A N ASP 313.A O no hydrogen 2.854 N/A HIS 317.A ND1 GLU 211.A OE1 no hydrogen 2.615 N/A ILE 318.A N LEU 314.A O no hydrogen 2.855 N/A ALA 319.A N LEU 315.A O no hydrogen 2.886 N/A THR 320.A N ASN 316.A O no hydrogen 2.824 N/A THR 320.A OG1 ASN 316.A O no hydrogen 2.891 N/A VAL 321.A N HIS 317.A O no hydrogen 2.828 N/A LEU 322.A N ILE 318.A O no hydrogen 3.012 N/A GLN 323.A N ALA 319.A O no hydrogen 2.910 N/A GLY 324.A N THR 320.A O no hydrogen 2.743 N/A GLN 325.A N VAL 321.A O no hydrogen 2.944 N/A GLN 325.A NE2 GLU 98.A O no hydrogen 2.666 N/A SER 326.A N LEU 322.A O no hydrogen 2.912 N/A SER 326.A OG.B LEU 322.A O no hydrogen 3.558 N/A SER 326.A OG.B GLN 323.A O no hydrogen 2.842 N/A THR 327.A N GLN 323.A O no hydrogen 3.154 N/A THR 327.A OG1 GLN 323.A O no hydrogen 2.849 N/A ALA 328.A N GLN 325.A O no hydrogen 3.161 N/A MET 329.A N GLY 324.A O no hydrogen 2.790 N/A