Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2qaf_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 5.A NE TYR 134.A O no hydrogen 3.153 N/A SER 7.A N PRO 4.A O no hydrogen 3.010 N/A PHE 10.A N GLU 242.A OE2 no hydrogen 3.306 N/A LYS 11.A N ASN 241.A O no hydrogen 2.885 N/A LYS 11.A NZ GLU 238.A OE1 no hydrogen 2.724 N/A VAL 12.A N GLY 9.A O no hydrogen 3.061 N/A LYS 13.A N GLY 9.A O no hydrogen 3.107 N/A LYS 13.A NZ ASP 167.A OD1 no hydrogen 3.171 N/A LYS 13.A NZ ASP 167.A OD2 no hydrogen 2.862 N/A LEU 14.A N PHE 10.A O no hydrogen 2.826 N/A GLU 15.A N LYS 11.A O no hydrogen 3.143 N/A LYS 16.A N VAL 12.A O no hydrogen 2.895 N/A ARG 17.A N LYS 13.A O no hydrogen 3.163 N/A ARG 17.A NE ALA 105.A O no hydrogen 2.795 N/A ARG 17.A NH2 ALA 105.A O no hydrogen 2.821 N/A ARG 18.A N LEU 14.A O no hydrogen 2.990 N/A ARG 18.A NE GLU 293.A OE1 no hydrogen 2.863 N/A ASN 19.A N GLU 15.A O no hydrogen 3.029 N/A ALA 20.A N LYS 16.A O no hydrogen 3.015 N/A ILE 21.A N ARG 17.A O no hydrogen 2.960 N/A ASN 22.A N ARG 18.A O no hydrogen 2.806 N/A ASN 22.A ND2 ASN 19.A O no hydrogen 3.351 N/A THR 23.A OG1 ASN 321.A OD1 no hydrogen 3.230 N/A CYS 24.A SG ILE 295.A O no hydrogen 3.268 N/A LEU 25.A N THR 23.A OG1 no hydrogen 3.393 N/A CYS 26.A N ILE 297.A O no hydrogen 2.783 N/A CYS 26.A SG THR 107.A O.A no hydrogen 3.898 N/A CYS 26.A SG THR 107.A OG1.B no hydrogen 2.949 N/A CYS 26.A SG ASN 298.A OD1 no hydrogen 3.411 N/A ILE 27.A N THR 107.A O.A no hydrogen 2.881 N/A ILE 27.A N THR 107.A O.B no hydrogen 3.041 N/A GLY 28.A N ILE 299.A O no hydrogen 2.938 N/A LEU 29.A N LYS 109.A O no hydrogen 2.834 N/A ASP 32.A N ASP 35.A OD2 no hydrogen 2.898 N/A ASP 35.A N ASP 32.A OD1 no hydrogen 2.806 N/A ILE 36.A N ASP 32.A O no hydrogen 3.164 N/A GLU 37.A N GLU 33.A O no hydrogen 3.016 N/A ASN 38.A N LYS 34.A O no hydrogen 2.820 N/A PHE 39.A N ASP 35.A O no hydrogen 2.969 N/A MET 40.A N ILE 36.A O no hydrogen 2.982 N/A LYS 41.A N GLU 37.A O no hydrogen 2.926 N/A ASN 42.A N ASN 38.A O no hydrogen 2.889 N/A GLU 43.A N PHE 39.A O no hydrogen 2.802 N/A LYS 44.A N MET 40.A O no hydrogen 2.929 N/A LYS 44.A NZ GLU 85.A OE2 no hydrogen 2.983 N/A GLU 45.A N LYS 41.A O no hydrogen 3.145 N/A ASN 46.A N GLU 43.A O no hydrogen 3.165 N/A ASN 46.A ND2 ASN 42.A O no hydrogen 2.806 N/A TYR 48.A N GLU 43.A O no hydrogen 2.749 N/A ASN 50.A ND2 GLU 43.A OE2 no hydrogen 3.106 N/A ILE 51.A N GLU 43.A OE1 no hydrogen 3.099 N/A LYS 52.A N TYR 48.A O no hydrogen 2.963 N/A LYS 53.A N ASN 49.A O.A no hydrogen 3.188 N/A LYS 53.A N ASN 49.A O.B no hydrogen 3.034 N/A ASN 54.A N ASN 50.A O no hydrogen 2.913 N/A ASN 54.A ND2 HIS 92.A ND1 no hydrogen 3.025 N/A ASN 54.A ND2 HIS 92.A O no hydrogen 2.928 N/A LEU 55.A N ILE 51.A O no hydrogen 2.917 N/A LYS 56.A N LYS 53.A O no hydrogen 3.122 N/A GLU 57.A N ASN 54.A O no hydrogen 3.012 N/A ILE 60.A N GLU 57.A O no hydrogen 3.425 N/A ASN 61.A N LYS 58.A O no hydrogen 2.982 N/A ASN 61.A ND2 LYS 58.A O no hydrogen 2.883 N/A ASN 62.A N TYR 59.A O no hydrogen 2.837 N/A SER 64.A N ASP 131.A OD2 no hydrogen 2.960 N/A SER 64.A OG ASP 131.A OD2 no hydrogen 2.479 N/A ILE 65.A N ASN 128.A OD1 no hydrogen 2.890 N/A LYS 66.A NZ GLU 84.A OE1 no hydrogen 2.657 N/A LYS 66.A NZ GLU 84.A OE2 no hydrogen 3.284 N/A LYS 67.A NZ VAL 63.A O no hydrogen 2.948 N/A LEU 70.A N LYS 66.A O no hydrogen 3.030 N/A LEU 71.A N LYS 67.A O no hydrogen 3.030 N/A LYS 72.A N ILE 69.A O no hydrogen 3.080 N/A ILE 77.A N ALA 73.A O no hydrogen 3.109 N/A ILE 78.A N PRO 74.A O no hydrogen 3.187 N/A ARG 79.A N ASP 75.A O no hydrogen 3.166 N/A GLU 80.A N ASN 76.A O no hydrogen 2.828 N/A GLU 81.A N ILE 77.A O no hydrogen 2.777 N/A GLU 84.A N GLU 81.A O no hydrogen 2.845 N/A GLU 85.A N LYS 82.A O no hydrogen 3.336 N/A TYR 88.A N GLU 84.A O no hydrogen 2.901 N/A TYR 88.A OH LYS 72.A O no hydrogen 2.698 N/A PHE 89.A N GLU 85.A O no hydrogen 2.993 N/A PHE 90.A N PHE 86.A O no hydrogen 2.865 N/A ASN 91.A N PHE 87.A O no hydrogen 2.869 N/A HIS 92.A N TYR 88.A O no hydrogen 2.882 N/A HIS 92.A NE2 LEU 70.A O no hydrogen 2.814 N/A PHE 93.A N PHE 89.A O no hydrogen 2.899 N/A CYS 94.A N PHE 90.A O no hydrogen 3.302 N/A CYS 94.A SG PHE 90.A O no hydrogen 3.616 N/A PHE 95.A N ASN 91.A O no hydrogen 3.084 N/A TYR 96.A N HIS 92.A O no hydrogen 2.889 N/A ILE 97.A N PHE 93.A O no hydrogen 2.937 N/A ILE 98.A N CYS 94.A O no hydrogen 2.926 N/A ASN 99.A N PHE 95.A O no hydrogen 2.731 N/A ASN 99.A ND2 ASN 54.A OD1 no hydrogen 2.966 N/A GLU 100.A N TYR 96.A O no hydrogen 2.893 N/A THR 101.A N ILE 97.A O no hydrogen 3.029 N/A THR 101.A OG1 ILE 97.A O no hydrogen 2.728 N/A ASN 102.A N ILE 98.A O no hydrogen 3.010 N/A ASN 102.A ND2 ILE 98.A O no hydrogen 2.806 N/A TYR 104.A N THR 101.A O no hydrogen 2.975 N/A ALA 105.A N ASN 102.A O no hydrogen 3.077 N/A LEU 106.A N LEU 25.A O no hydrogen 2.871 N/A THR 107.A OG1.A PHE 108.A O no hydrogen 3.369 N/A THR 107.A OG1.A PRO 139.A O no hydrogen 3.101 N/A PHE 108.A N PRO 139.A O no hydrogen 2.993 N/A LYS 109.A N ILE 27.A O no hydrogen 2.905 N/A LYS 109.A NZ ASP 143.A OD2 no hydrogen 2.514 N/A MET 110.A N ILE 141.A O no hydrogen 3.007 N/A ASN 111.A N ASP 30.A OD1 no hydrogen 3.005 N/A PHE 112.A N ASP 143.A O no hydrogen 2.980 N/A ALA 113.A N ASN 111.A OD1 no hydrogen 3.027 N/A PHE 114.A N ASN 111.A O no hydrogen 3.122 N/A TYR 115.A N PHE 112.A O no hydrogen 2.894 N/A TYR 115.A OH LEU 29.A O no hydrogen 2.931 N/A GLY 119.A N ILE 116.A O no hydrogen 3.035 N/A ASP 124.A N SER 120.A O no hydrogen 3.121 N/A VAL 125.A N VAL 121.A O no hydrogen 3.137 N/A LEU 126.A N GLY 122.A O no hydrogen 2.773 N/A LYS 127.A N ILE 123.A O no hydrogen 2.971 N/A LYS 127.A NZ ASP 131.A OD1 no hydrogen 2.877 N/A LYS 127.A NZ TYR 163.A O no hydrogen 2.831 N/A ASN 128.A N ASP 124.A O no hydrogen 3.145 N/A ASN 128.A ND2 ILE 65.A O no hydrogen 2.972 N/A ASN 128.A ND2 ASN 91.A OD1 no hydrogen 2.896 N/A VAL 129.A N VAL 125.A O no hydrogen 2.916 N/A PHE 130.A N LEU 126.A O no hydrogen 2.920 N/A ASP 131.A N LYS 127.A O no hydrogen 2.877 N/A TYR 132.A N ASN 128.A O no hydrogen 2.904 N/A TYR 132.A OH ASN 99.A OD1 no hydrogen 2.658 N/A LEU 133.A N VAL 129.A O no hydrogen 3.094 N/A TYR 134.A N PHE 130.A O no hydrogen 2.993 N/A GLU 135.A N ASP 131.A O no hydrogen 3.072 N/A LEU 136.A N TYR 132.A O no hydrogen 3.081 N/A ASN 137.A N TYR 134.A O no hydrogen 3.124 N/A ILE 138.A N LEU 133.A O no hydrogen 3.088 N/A THR 140.A N ASP 167.A OD2 no hydrogen 2.895 N/A THR 140.A OG1 ASP 167.A OD2 no hydrogen 3.269 N/A ILE 141.A N PHE 108.A O no hydrogen 2.955 N/A LEU 142.A N SER 168.A O no hydrogen 2.966 N/A ASP 143.A N MET 110.A O no hydrogen 2.859 N/A MET 144.A N THR 170.A OG1 no hydrogen 2.958 N/A LYS 145.A N THR 170.A OG1 no hydrogen 2.937 N/A LYS 145.A NZ ASP 143.A OD2 no hydrogen 3.242 N/A ILE 146.A N THR 170.A O no hydrogen 3.332 N/A ASN 147.A ND2 LYS 145.A O no hydrogen 3.689 N/A ILE 149.A N ASP 148.A OD1 no hydrogen 2.758 N/A THR 152.A N ILE 149.A O no hydrogen 3.124 N/A VAL 153.A N ILE 149.A O no hydrogen 2.938 N/A LYS 154.A N GLY 150.A O no hydrogen 3.390 N/A ASN 155.A N THR 152.A O no hydrogen 3.062 N/A ASN 155.A ND2 THR 152.A O no hydrogen 2.930 N/A ARG 157.A N VAL 153.A O no hydrogen 3.058 N/A ARG 157.A NH1 ASP 182.A O no hydrogen 3.094 N/A LYS 158.A N LYS 154.A O no hydrogen 2.972 N/A PHE 159.A N ASN 155.A O no hydrogen 2.930 N/A ILE 160.A N TYR 156.A O no hydrogen 2.746 N/A PHE 161.A N ARG 157.A O no hydrogen 2.861 N/A GLU 162.A N LYS 158.A O no hydrogen 3.122 N/A TYR 163.A N LYS 158.A O no hydrogen 2.950 N/A LEU 164.A N PHE 159.A O no hydrogen 2.903 N/A SER 166.A N ILE 160.A O no hydrogen 2.979 N/A SER 166.A OG SER 168.A O no hydrogen 2.714 N/A ASP 167.A N THR 140.A OG1 no hydrogen 3.036 N/A SER 168.A N SER 166.A OG no hydrogen 3.367 N/A SER 168.A OG THR 140.A O no hydrogen 3.015 N/A CYS 169.A SG THR 170.A O no hydrogen 4.017 N/A THR 170.A N LEU 142.A O no hydrogen 3.224 N/A THR 170.A OG1 ASP 143.A OD1 no hydrogen 2.686 N/A VAL 171.A N PHE 196.A O no hydrogen 2.925 N/A ASN 172.A N ILE 146.A O no hydrogen 2.880 N/A TYR 174.A N ASN 172.A OD1 no hydrogen 3.029 N/A GLY 176.A N ILE 173.A O no hydrogen 2.747 N/A LEU 180.A N THR 177.A O no hydrogen 2.974 N/A LYS 181.A N ASN 178.A O no hydrogen 3.111 N/A ASP 182.A N MET 179.A O no hydrogen 2.924 N/A ILE 183.A N LEU 180.A O no hydrogen 3.244 N/A CYS 184.A N LEU 180.A O no hydrogen 2.820 N/A ASP 186.A N LYS 191.A O no hydrogen 2.805 N/A GLU 188.A N ASP 186.A OD1 no hydrogen 2.944 N/A LYS 189.A N ASP 186.A OD1 no hydrogen 3.370 N/A ASN 190.A ND2 TYR 185.A OH no hydrogen 2.593 N/A LYS 191.A N ASP 186.A O no hydrogen 3.274 N/A TYR 193.A N CYS 184.A O no hydrogen 2.832 N/A SER 194.A OG GLU 242.A OE1 no hydrogen 2.577 N/A SER 194.A OG PHE 243.A O no hydrogen 3.493 N/A ALA 195.A N PHE 243.A O no hydrogen 3.133 N/A PHE 196.A N CYS 169.A O no hydrogen 2.819 N/A VAL 197.A N GLY 245.A O no hydrogen 2.726 N/A LEU 198.A N VAL 171.A O no hydrogen 3.012 N/A VAL 199.A N VAL 247.A O no hydrogen 3.086 N/A LYS 200.A N VAL 247.A O no hydrogen 3.106 N/A LYS 200.A NZ THR 201.A O no hydrogen 3.390 N/A LYS 200.A NZ SER 206.A OG no hydrogen 2.871 N/A LYS 200.A NZ SER 252.A OG no hydrogen 2.859 N/A THR 201.A N GLN 210.A OE1 no hydrogen 2.836 N/A THR 202.A OG1 GLN 276.A OE1 no hydrogen 2.644 N/A ASN 203.A ND2 THR 201.A OG1 no hydrogen 2.873 N/A SER 206.A N ASN 203.A O no hydrogen 2.954 N/A SER 206.A OG THR 201.A O no hydrogen 3.038 N/A SER 206.A OG ASN 203.A O no hydrogen 3.092 N/A ILE 208.A N ASP 205.A O no hydrogen 3.099 N/A GLN 210.A N SER 206.A O no hydrogen 3.442 N/A GLN 210.A NE2 THR 201.A OG1 no hydrogen 2.903 N/A LYS 211.A N ALA 207.A O no hydrogen 3.047 N/A LYS 211.A NZ GLU 255.A OE2 no hydrogen 2.753 N/A ASN 212.A N ALA 207.A O no hydrogen 2.985 N/A LEU 213.A N PHE 209.A O no hydrogen 3.345 N/A LEU 215.A N LYS 218.A O no hydrogen 2.932 N/A LYS 218.A N LEU 215.A O no hydrogen 3.101 N/A ALA 220.A N LEU 213.A O no hydrogen 2.919 N/A TYR 221.A N GLN 210.A O no hydrogen 3.069 N/A ILE 223.A N GLN 219.A O no hydrogen 3.189 N/A MET 224.A N ALA 220.A O no hydrogen 2.800 N/A ALA 225.A N TYR 221.A O no hydrogen 3.008 N/A GLN 226.A N VAL 222.A O no hydrogen 3.015 N/A GLN 226.A NE2 GLN 226.A O no hydrogen 3.377 N/A GLN 226.A NE2 ASN 230.A OD1 no hydrogen 2.751 N/A GLU 227.A N ILE 223.A O no hydrogen 2.931 N/A ALA 228.A N MET 224.A O no hydrogen 3.063 N/A LEU 229.A N ALA 225.A O no hydrogen 3.056 N/A ASN 230.A N GLN 226.A O no hydrogen 2.907 N/A MET 231.A N GLU 227.A O no hydrogen 3.074 N/A SER 232.A N ALA 228.A O no hydrogen 2.936 N/A SER 233.A N LEU 229.A O no hydrogen 2.991 N/A SER 233.A OG LEU 229.A O no hydrogen 3.364 N/A TYR 234.A N ASN 230.A O no hydrogen 3.002 N/A LEU 235.A N MET 231.A O no hydrogen 2.988 N/A ASN 236.A N SER 233.A O no hydrogen 3.187 N/A LEU 237.A N SER 232.A O no hydrogen 3.263 N/A ASN 240.A N LEU 237.A O no hydrogen 2.793 N/A ASN 240.A ND2 ASN 236.A O no hydrogen 2.962 N/A ASN 241.A N GLU 238.A O no hydrogen 3.145 N/A GLU 242.A N LEU 237.A O no hydrogen 2.948 N/A PHE 243.A N SER 194.A OG no hydrogen 2.978 N/A GLY 245.A N ALA 195.A O no hydrogen 2.837 N/A PHE 246.A N TYR 267.A O no hydrogen 2.783 N/A VAL 247.A N VAL 197.A O no hydrogen 2.781 N/A VAL 248.A N LEU 269.A O no hydrogen 3.061 N/A GLY 249.A N LYS 200.A O no hydrogen 2.793 N/A ALA 250.A N PRO 271.A O no hydrogen 2.757 N/A ASN 251.A ND2 THR 202.A O no hydrogen 3.258 N/A SER 252.A N GLY 249.A O no hydrogen 3.038 N/A SER 252.A OG ASN 251.A OD1 no hydrogen 3.261 N/A MET 256.A N SER 252.A O no hydrogen 2.994 N/A ASN 257.A N TYR 253.A O no hydrogen 3.034 N/A TYR 258.A N ASP 254.A O no hydrogen 2.974 N/A ILE 259.A N GLU 255.A O no hydrogen 2.857 N/A ARG 260.A N MET 256.A O no hydrogen 2.986 N/A ARG 260.A NE GLY 287.A O no hydrogen 2.832 N/A ARG 260.A NH1 PRO 264.A O no hydrogen 2.875 N/A ARG 260.A NH1 CYS 266.A O no hydrogen 3.004 N/A ARG 260.A NH2 CYS 266.A O no hydrogen 3.338 N/A ARG 260.A NH2 GLY 287.A O no hydrogen 3.197 N/A ARG 260.A NH2 LYS 294.A O no hydrogen 2.863 N/A THR 261.A N ASN 257.A O no hydrogen 2.908 N/A THR 261.A OG1 ASN 257.A O no hydrogen 2.830 N/A TYR 262.A N TYR 258.A O no hydrogen 2.804 N/A PHE 263.A N ILE 259.A O no hydrogen 2.771 N/A ASN 265.A ND2 HIS 289.A NE2 no hydrogen 2.917 N/A CYS 266.A N PHE 263.A O no hydrogen 3.190 N/A CYS 266.A SG PHE 263.A O no hydrogen 3.172 N/A ILE 268.A N LYS 294.A O no hydrogen 2.801 N/A LEU 269.A N PHE 246.A O no hydrogen 2.763 N/A SER 270.A N LEU 296.A O no hydrogen 2.745 N/A SER 270.A OG VAL 248.A O no hydrogen 2.920 N/A ASN 277.A N.A GLY 274.A O no hydrogen 2.976 N/A ASN 277.A N.B GLY 274.A O no hydrogen 2.964 N/A GLY 278.A N GLY 272.A O no hydrogen 2.920 N/A ASP 279.A N TYR 253.A OH no hydrogen 2.991 N/A LYS 282.A N ASP 279.A OD1 no hydrogen 3.320 N/A THR 283.A N ASP 279.A O no hydrogen 2.952 N/A THR 283.A OG1 ALA 250.A O no hydrogen 2.470 N/A THR 283.A OG1 ASP 279.A O no hydrogen 3.054 N/A LEU 284.A N LEU 280.A O no hydrogen 2.990 N/A THR 285.A N HIS 281.A O no hydrogen 3.040 N/A THR 285.A OG1 HIS 281.A O no hydrogen 2.894 N/A ASN 286.A N LYS 282.A O no hydrogen 2.945 N/A GLY 287.A N THR 283.A O no hydrogen 2.873 N/A SER 291.A N HIS 289.A ND1 no hydrogen 2.949 N/A GLU 293.A N GLU 293.A OE1 no hydrogen 3.060 N/A LYS 294.A N SER 291.A O no hydrogen 2.836 N/A LYS 294.A NZ ASN 265.A O no hydrogen 3.209 N/A ILE 295.A N TYR 292.A O no hydrogen 3.185 N/A LEU 296.A N ILE 268.A O no hydrogen 2.881 N/A ILE 297.A N CYS 24.A O no hydrogen 2.919 N/A ASN 298.A N SER 270.A O no hydrogen 3.122 N/A ILE 299.A N CYS 26.A O no hydrogen 2.940 N/A ILE 303.A N GLY 300.A O no hydrogen 2.972 N/A THR 304.A N GLY 300.A O no hydrogen 2.991 N/A THR 304.A OG1 GLY 300.A O no hydrogen 3.463 N/A LYS 305.A N ARG 301.A O no hydrogen 2.860 N/A LYS 305.A NZ ASP 32.A OD1 no hydrogen 3.163 N/A LYS 305.A NZ ASP 32.A OD2 no hydrogen 2.721 N/A LYS 305.A NZ ASP 35.A OD1 no hydrogen 2.744 N/A ASN 306.A N ILE 303.A O no hydrogen 3.193 N/A TYR 308.A N ASN 306.A OD1 no hydrogen 2.769 N/A LYS 311.A NZ GLN 314.A OE1 no hydrogen 3.196 N/A ALA 312.A N TYR 308.A O no hydrogen 2.917 N/A ALA 313.A N PRO 309.A O no hydrogen 2.895 N/A GLN 314.A N GLN 310.A O no hydrogen 2.988 N/A MET 315.A N LYS 311.A O no hydrogen 2.982 N/A TYR 316.A N ALA 312.A O no hydrogen 3.144 N/A TYR 317.A N ALA 313.A O no hydrogen 2.837 N/A TYR 317.A OH ILE 21.A O no hydrogen 2.696 N/A ASP 318.A N GLN 314.A O no hydrogen 2.824 N/A GLN 319.A N MET 315.A O no hydrogen 2.878 N/A ILE 320.A N TYR 316.A O no hydrogen 2.849 N/A ASN 321.A N TYR 317.A O no hydrogen 2.984 N/A ALA 322.A N ASP 318.A O no hydrogen 3.037 N/A ILE 323.A N GLN 319.A O no hydrogen 3.156 N/A LEU 324.A N ILE 320.A O no hydrogen 2.774 N/A LYS 325.A N ASN 321.A O no hydrogen 2.815 N/A GLN 326.A N ALA 322.A O no hydrogen 3.192 N/A ASN 327.A N ILE 323.A O no hydrogen 3.210 N/A MET 328.A N LEU 324.A O no hydrogen 2.995 N/A