Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2r3o_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 2.A N GLU 2.A OE1 no hydrogen 2.908 N/A PHE 4.A N MET 1.A O no hydrogen 2.753 N/A GLN 5.A N ARG 22.A O no hydrogen 2.713 N/A VAL 7.A N LYS 20.A O no hydrogen 2.669 N/A GLU 8.A N LYS 20.A O no hydrogen 3.369 N/A ILE 10.A N VAL 18.A O no hydrogen 2.950 N/A GLY 13.A N GLY 16.A O no hydrogen 2.613 N/A VAL 18.A N GLY 11.A O no hydrogen 2.841 N/A TYR 19.A N LEU 32.A O no hydrogen 2.852 N/A LYS 20.A N GLU 8.A O no hydrogen 2.767 N/A ALA 21.A N VAL 30.A O no hydrogen 2.873 N/A ARG 22.A N GLN 5.A O no hydrogen 2.743 N/A ARG 22.A NH1 GLN 5.A OE1 no hydrogen 3.118 N/A ASN 23.A N GLU 28.A O no hydrogen 2.767 N/A LYS 24.A N ASN 3.A O no hydrogen 2.615 N/A LYS 24.A NZ GLU 2.A O no hydrogen 3.212 N/A LEU 25.A N ASN 23.A OD1 no hydrogen 2.603 N/A THR 26.A N ASN 23.A OD1 no hydrogen 3.013 N/A GLY 27.A N ASN 23.A O no hydrogen 2.711 N/A VAL 30.A N ALA 21.A O no hydrogen 2.817 N/A ALA 31.A N PHE 73.A O no hydrogen 2.918 N/A LEU 32.A N TYR 19.A O no hydrogen 2.652 N/A LYS 33.A N LEU 71.A O no hydrogen 2.837 N/A LYS 33.A NZ ASP 138.A OD1 no hydrogen 2.692 N/A LYS 33.A NZ ASP 138.A OD2 no hydrogen 3.326 N/A LYS 34.A N VAL 17.A O no hydrogen 3.277 N/A ILE 35.A N LEU 69.A O no hydrogen 2.780 N/A ARG 36.A N TYR 15.A O no hydrogen 3.257 N/A ILE 42.A N PRO 38.A O no hydrogen 3.403 N/A ARG 43.A N SER 39.A O no hydrogen 3.121 N/A GLU 44.A N THR 40.A O no hydrogen 3.157 N/A ILE 45.A N ALA 41.A O no hydrogen 2.856 N/A SER 46.A N ILE 42.A O no hydrogen 2.846 N/A SER 46.A OG ILE 42.A O no hydrogen 2.758 N/A LEU 47.A N ARG 43.A O no hydrogen 3.031 N/A LEU 48.A N ILE 45.A O no hydrogen 2.804 N/A LYS 49.A N SER 46.A O no hydrogen 3.092 N/A GLU 50.A N LEU 47.A O no hydrogen 3.058 N/A LEU 51.A N LEU 48.A O no hydrogen 3.053 N/A ASN 52.A N GLU 50.A O no hydrogen 2.901 N/A ASN 52.A ND2 LYS 49.A O no hydrogen 3.356 N/A ASN 55.A ND2 GLN 103.A OE1 no hydrogen 3.104 N/A ASN 55.A ND2 ILE 134.A O no hydrogen 2.929 N/A ILE 56.A N HIS 53.A O no hydrogen 2.991 N/A VAL 57.A N LEU 136.A O no hydrogen 2.971 N/A LYS 58.A N GLU 74.A OE1 no hydrogen 2.876 N/A LEU 60.A N VAL 72.A O no hydrogen 2.593 N/A ASP 61.A N VAL 72.A O no hydrogen 3.177 N/A ILE 63.A N TYR 70.A O no hydrogen 2.762 N/A HIS 64.A ND1 LYS 68.A O no hydrogen 2.662 N/A THR 65.A N LYS 68.A O no hydrogen 2.792 N/A TYR 70.A N ILE 63.A O no hydrogen 2.684 N/A LEU 71.A N LYS 33.A O no hydrogen 2.860 N/A VAL 72.A N ASP 61.A O no hydrogen 2.859 N/A PHE 73.A N ALA 31.A O no hydrogen 2.843 N/A GLU 74.A N LYS 58.A O no hydrogen 2.906 N/A LEU 80.A N LEU 126.A O no hydrogen 2.616 N/A LYS 82.A N ASP 79.A OD1 no hydrogen 2.823 N/A PHE 83.A N ASP 79.A O no hydrogen 2.997 N/A MET 84.A N LEU 80.A O no hydrogen 2.918 N/A ASP 85.A N LYS 81.A O no hydrogen 3.036 N/A ALA 86.A N LYS 82.A O no hydrogen 2.953 N/A SER 87.A N MET 84.A O no hydrogen 3.176 N/A SER 87.A OG PHE 83.A O no hydrogen 2.294 N/A ALA 88.A N ASP 85.A O no hydrogen 3.175 N/A GLY 91.A N SER 87.A O no hydrogen 2.429 N/A LEU 96.A N PRO 93.A O no hydrogen 2.920 N/A ILE 97.A N PRO 93.A O no hydrogen 3.047 N/A LYS 98.A N LEU 94.A O no hydrogen 2.746 N/A LYS 98.A NZ PHE 277.A O no hydrogen 2.893 N/A LYS 98.A NZ ASP 280.A OD1 no hydrogen 2.523 N/A SER 99.A N PRO 95.A O no hydrogen 3.019 N/A TYR 100.A N LEU 96.A O no hydrogen 2.866 N/A LEU 101.A N ILE 97.A O no hydrogen 2.923 N/A PHE 102.A N LYS 98.A O no hydrogen 2.998 N/A GLN 103.A N SER 99.A O no hydrogen 3.048 N/A GLN 103.A NE2 SER 99.A O no hydrogen 3.417 N/A GLN 103.A NE2 SER 99.A OG no hydrogen 2.960 N/A GLN 103.A NE2 GLY 132.A O no hydrogen 2.876 N/A LEU 104.A N TYR 100.A O no hydrogen 2.923 N/A LEU 105.A N LEU 101.A O no hydrogen 2.896 N/A GLN 106.A N PHE 102.A O no hydrogen 3.015 N/A GLN 106.A NE2 PHE 102.A O no hydrogen 3.463 N/A GLY 107.A N GLN 103.A O no hydrogen 3.000 N/A LEU 108.A N LEU 104.A O no hydrogen 2.804 N/A ALA 109.A N LEU 105.A O no hydrogen 2.773 N/A PHE 110.A N GLN 106.A O no hydrogen 3.033 N/A CYS 111.A N GLY 107.A O no hydrogen 3.078 N/A CYS 111.A SG GLY 107.A O no hydrogen 3.568 N/A HIS 112.A N LEU 108.A O no hydrogen 2.766 N/A HIS 112.A NE2 ASP 177.A OD2 no hydrogen 2.977 N/A SER 113.A N ALA 109.A O no hydrogen 3.027 N/A SER 113.A OG PHE 110.A O no hydrogen 2.631 N/A HIS 114.A N CYS 111.A O no hydrogen 2.863 N/A HIS 114.A ND1 PHE 110.A O no hydrogen 3.327 N/A ARG 115.A N HIS 112.A O no hydrogen 2.872 N/A VAL 116.A N CYS 111.A O no hydrogen 2.953 N/A HIS 118.A N ASP 177.A OD2 no hydrogen 2.708 N/A HIS 118.A NE2 ALA 137.A O no hydrogen 2.667 N/A ARG 119.A N ASP 177.A OD1 no hydrogen 2.687 N/A ASP 120.A N HIS 118.A ND1 no hydrogen 3.000 N/A LYS 122.A N ASN 125.A OD1.A no hydrogen 2.864 N/A LYS 122.A NZ ASP 120.A OD2 no hydrogen 2.900 N/A ASN 125.A N.A LYS 122.A O no hydrogen 2.822 N/A ASN 125.A N.B LYS 122.A O no hydrogen 2.758 N/A ASN 125.A N.C LYS 122.A O no hydrogen 2.765 N/A ASN 125.A ND2.A ASP 120.A O no hydrogen 2.744 N/A ASN 125.A ND2.B ASP 120.A O no hydrogen 3.011 N/A ASN 125.A ND2.C ASP 120.A O no hydrogen 3.019 N/A LEU 126.A N PRO 123.A O no hydrogen 3.113 N/A LEU 127.A N LYS 135.A O no hydrogen 2.971 N/A ILE 128.A N GLN 78.A O no hydrogen 2.885 N/A ASN 129.A N ALA 133.A O no hydrogen 3.289 N/A THR 130.A OG1 GLU 131.A OE2 no hydrogen 3.515 N/A GLU 131.A N ASN 129.A OD1 no hydrogen 2.787 N/A ALA 133.A N ASN 129.A OD1 no hydrogen 3.200 N/A ILE 134.A N GLN 103.A OE1 no hydrogen 3.101 N/A LYS 135.A N LEU 127.A O no hydrogen 2.770 N/A LYS 135.A NZ GLU 74.A OE1 no hydrogen 3.344 N/A LYS 135.A NZ GLU 74.A OE2 no hydrogen 2.805 N/A LEU 136.A N ASN 55.A O no hydrogen 2.833 N/A ALA 137.A N ASN 125.A O.A no hydrogen 2.732 N/A ALA 137.A N ASN 125.A O.B no hydrogen 2.759 N/A ALA 137.A N ASN 125.A O.C no hydrogen 2.757 N/A LEU 141.A N ASP 138.A O no hydrogen 3.193 N/A ALA 144.A N GLY 140.A O no hydrogen 3.125 N/A PHE 145.A N LEU 141.A O no hydrogen 2.819 N/A GLY 146.A N ALA 142.A O no hydrogen 2.509 N/A ARG 150.A NH1 HIS 154.A O no hydrogen 3.117 N/A THR 151.A N GLU 155.A O no hydrogen 2.661 N/A TYR 152.A N THR 14.A O no hydrogen 3.349 N/A THR 153.A N THR 151.A OG1 no hydrogen 3.040 N/A THR 153.A OG1 GLU 12.A OE2 no hydrogen 3.382 N/A THR 153.A OG1 THR 151.A OG1 no hydrogen 2.683 N/A HIS 154.A N THR 151.A O no hydrogen 2.519 N/A VAL 157.A N VAL 149.A O no hydrogen 3.082 N/A TYR 161.A OH GLU 187.A OE1 no hydrogen 2.645 N/A ARG 162.A N LEU 159.A O no hydrogen 2.998 N/A GLU 165.A N GLU 165.A OE1 no hydrogen 2.701 N/A ILE 166.A N ALA 163.A O no hydrogen 3.023 N/A LEU 167.A N ALA 163.A O no hydrogen 3.314 N/A LEU 168.A N PRO 164.A O no hydrogen 2.805 N/A GLY 169.A N ILE 166.A O no hydrogen 3.070 N/A ALA 175.A N SER 173.A OG no hydrogen 3.007 N/A VAL 176.A N SER 173.A O no hydrogen 2.996 N/A ASP 177.A N THR 174.A O no hydrogen 3.052 N/A TRP 179.A N ALA 175.A O no hydrogen 3.120 N/A SER 180.A N VAL 176.A O no hydrogen 3.204 N/A SER 180.A OG TYR 161.A O no hydrogen 2.703 N/A SER 180.A OG VAL 176.A O no hydrogen 3.137 N/A LEU 181.A N ASP 177.A O no hydrogen 2.977 N/A GLY 182.A N ILE 178.A O no hydrogen 2.889 N/A CYS 183.A N TRP 179.A O no hydrogen 3.021 N/A CYS 183.A SG TRP 179.A O no hydrogen 3.517 N/A ILE 184.A N SER 180.A O no hydrogen 3.014 N/A PHE 185.A N LEU 181.A O no hydrogen 2.831 N/A ALA 186.A N GLY 182.A O no hydrogen 3.044 N/A GLU 187.A N CYS 183.A O no hydrogen 3.098 N/A MET 188.A N ILE 184.A O no hydrogen 2.893 N/A VAL 189.A N PHE 185.A O no hydrogen 3.039 N/A THR 190.A N ALA 186.A O no hydrogen 2.977 N/A THR 190.A OG1 ALA 186.A O no hydrogen 3.016 N/A ARG 191.A N GLU 187.A O no hydrogen 2.897 N/A ARG 191.A NH1 ALA 88.A O no hydrogen 3.213 N/A ARG 192.A N THR 190.A OG1 no hydrogen 3.352 N/A GLY 197.A N PHE 195.A O no hydrogen 2.907 N/A ASP 198.A N ASP 202.A OD2 no hydrogen 3.086 N/A ASP 202.A N SER 199.A OG no hydrogen 2.967 N/A GLN 203.A N SER 199.A O no hydrogen 2.845 N/A GLN 203.A NE2 TRP 160.A O no hydrogen 3.193 N/A GLN 203.A NE2 PHE 195.A O no hydrogen 2.982 N/A LEU 204.A N GLU 200.A O no hydrogen 2.975 N/A PHE 205.A N ILE 201.A O no hydrogen 2.873 N/A ARG 206.A N ASP 202.A O no hydrogen 2.863 N/A ARG 206.A NE ASP 202.A OD2 no hydrogen 2.881 N/A ILE 207.A N GLN 203.A O no hydrogen 3.071 N/A PHE 208.A N LEU 204.A O no hydrogen 2.941 N/A ARG 209.A N PHE 205.A O no hydrogen 2.860 N/A ARG 209.A NH2 ASP 202.A OD1 no hydrogen 3.540 N/A THR 210.A N ILE 207.A O no hydrogen 3.146 N/A THR 210.A OG1 ARG 206.A O no hydrogen 3.498 N/A LEU 211.A N ILE 207.A O no hydrogen 2.788 N/A GLY 212.A N PHE 208.A O no hydrogen 2.637 N/A THR 213.A N TRP 235.A O no hydrogen 2.937 N/A THR 213.A OG1 PRO 233.A O no hydrogen 2.580 N/A VAL 218.A N ASP 215.A OD1 no hydrogen 3.130 N/A TRP 219.A N ASP 215.A O no hydrogen 2.860 N/A GLY 221.A N GLU 216.A OE1 no hydrogen 2.763 N/A VAL 222.A N TRP 219.A O no hydrogen 2.948 N/A THR 223.A N GLU 216.A OE2 no hydrogen 3.047 N/A THR 223.A OG1 GLU 216.A OE2 no hydrogen 2.449 N/A SER 224.A N.A GLY 221.A O no hydrogen 3.070 N/A SER 224.A N.B GLY 221.A O no hydrogen 3.054 N/A SER 224.A OG.A GLY 221.A O no hydrogen 2.969 N/A MET 225.A N.A VAL 222.A O no hydrogen 3.152 N/A MET 225.A N.B VAL 222.A O no hydrogen 3.024 N/A ASP 227.A N LEU 168.A O no hydrogen 2.794 N/A TYR 228.A N MET 225.A O.A no hydrogen 3.151 N/A TYR 228.A N MET 225.A O.B no hydrogen 3.026 N/A PHE 232.A N LYS 229.A O no hydrogen 2.953 N/A LYS 234.A NZ TYR 228.A OH no hydrogen 3.408 N/A LYS 234.A NZ PHE 232.A O no hydrogen 2.952 N/A TRP 235.A N THR 213.A OG1 no hydrogen 2.811 N/A ARG 237.A NH1 LEU 211.A O no hydrogen 3.003 N/A GLN 238.A N THR 210.A O no hydrogen 2.838 N/A LYS 242.A N ASP 239.A O no hydrogen 2.851 N/A VAL 243.A N PHE 240.A O no hydrogen 3.050 N/A VAL 244.A N PHE 240.A O no hydrogen 3.098 N/A LEU 247.A N VAL 244.A O no hydrogen 2.711 N/A GLY 251.A N ASP 248.A OD1 no hydrogen 2.905 N/A ARG 252.A N ASP 248.A O no hydrogen 2.963 N/A ARG 252.A NH1 LEU 247.A O no hydrogen 2.855 N/A ARG 252.A NH2 GLU 249.A OE1 no hydrogen 2.852 N/A SER 253.A N GLU 249.A O no hydrogen 2.815 N/A SER 253.A OG HIS 275.A NE2 no hydrogen 3.154 N/A LEU 254.A N ASP 250.A O no hydrogen 2.981 N/A LEU 255.A N GLY 251.A O no hydrogen 2.837 N/A SER 256.A N.A ARG 252.A O no hydrogen 2.867 N/A SER 256.A N.B ARG 252.A O no hydrogen 2.932 N/A SER 256.A OG.A SER 253.A O no hydrogen 2.734 N/A GLN 257.A N.A SER 253.A O no hydrogen 3.237 N/A GLN 257.A N.B SER 253.A O no hydrogen 3.198 N/A GLN 257.A NE2.A SER 253.A O no hydrogen 3.305 N/A GLN 257.A NE2.A SER 253.A OG no hydrogen 3.218 N/A MET 258.A N LEU 254.A O no hydrogen 3.004 N/A LEU 259.A N LEU 255.A O no hydrogen 3.039 N/A LEU 259.A N SER 256.A O.A no hydrogen 3.308 N/A LEU 259.A N SER 256.A O.B no hydrogen 3.256 N/A HIS 260.A N GLN 257.A O.A no hydrogen 3.306 N/A TYR 261.A OH GLY 212.A O no hydrogen 2.506 N/A ASN 264.A N ASP 262.A OD1 no hydrogen 2.972 N/A LYS 265.A N ASP 262.A O no hydrogen 2.821 N/A LYS 265.A NZ VAL 218.A O no hydrogen 3.108 N/A LYS 265.A NZ ASP 262.A OD2 no hydrogen 2.966 N/A ARG 266.A N ASP 262.A O no hydrogen 2.935 N/A ARG 266.A NE HIS 260.A O no hydrogen 2.832 N/A ARG 266.A NH1 GLU 165.A OE1 no hydrogen 3.446 N/A ARG 266.A NH1 GLU 165.A OE2 no hydrogen 2.878 N/A ARG 266.A NH1 ALA 175.A O no hydrogen 2.890 N/A ARG 266.A NH2 GLU 165.A OE1 no hydrogen 2.881 N/A ARG 266.A NH2 GLU 165.A OE2 no hydrogen 3.562 N/A ARG 266.A NH2 HIS 260.A O no hydrogen 3.286 N/A ARG 266.A NH2 TYR 261.A O no hydrogen 2.920 N/A ILE 267.A N GLN 257.A O.A no hydrogen 3.347 N/A ILE 267.A N GLN 257.A O.B no hydrogen 2.797 N/A ALA 271.A N SER 268.A OG no hydrogen 2.987 N/A ALA 272.A N SER 268.A O no hydrogen 2.895 N/A LEU 273.A N ALA 269.A O no hydrogen 2.957 N/A ALA 274.A N ALA 271.A O no hydrogen 3.148 N/A HIS 275.A N ALA 272.A O no hydrogen 2.955 N/A HIS 275.A NE2 SER 253.A OG no hydrogen 3.154 N/A PHE 277.A N HIS 275.A ND1 no hydrogen 2.889 N/A PHE 278.A N HIS 275.A O no hydrogen 2.949 N/A GLN 279.A N PRO 276.A O no hydrogen 2.917 N/A VAL 281.A N PHE 278.A O no hydrogen 3.174 N/A ARG 289.A NE LEU 288.A O no hydrogen 3.259 N/A ARG 289.A NH2 LEU 288.A O no hydrogen 3.537 N/A