Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2r49_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A N ASP 209.A OD2 no hydrogen 3.552 N/A LYS 3.A N ASP 209.A OD1 no hydrogen 3.137 N/A LYS 3.A NZ THR 202.A OG1 no hydrogen 2.888 N/A LYS 3.A NZ ASN 206.A O no hydrogen 2.796 N/A SER 6.A N THR 227.A O no hydrogen 2.848 N/A SER 6.A OG ASN 214.A OD1 no hydrogen 3.365 N/A SER 6.A OG THR 227.A O no hydrogen 3.390 N/A SER 6.A OG GLU 232.A OE1 no hydrogen 2.681 N/A GLY 7.A N ASP 209.A O no hydrogen 2.771 N/A ALA 8.A N LEU 138.A O no hydrogen 3.074 N/A LEU 10.A N PHE 136.A O no hydrogen 2.794 N/A TYR 11.A N GLY 197.A O no hydrogen 2.972 N/A THR 12.A N LEU 134.A O no hydrogen 3.033 N/A THR 12.A OG1 GLU 14.A O no hydrogen 2.829 N/A LEU 13.A N ARG 195.A O no hydrogen 2.852 N/A VAL 16.A N GLN 132.A O no hydrogen 2.943 N/A GLN 17.A NE2 GLY 130.A O no hydrogen 3.572 N/A GLY 19.A N TRP 103.A O no hydrogen 2.899 N/A LYS 20.A N TYR 167.A O no hydrogen 3.060 N/A PHE 21.A N LEU 101.A O no hydrogen 2.737 N/A GLU 22.A N LYS 165.A O no hydrogen 3.028 N/A ALA 23.A N TYR 99.A O no hydrogen 3.001 N/A ARG 24.A N TRP 163.A O no hydrogen 2.858 N/A ARG 24.A NE ASP 241.A OD1 no hydrogen 2.841 N/A ARG 24.A NH1 THR 98.A OG1 no hydrogen 2.757 N/A ARG 24.A NH2 ASP 241.A OD2 no hydrogen 3.069 N/A MET 25.A N HIS 97.A O no hydrogen 2.856 N/A LYS 26.A N PHE 160.A O no hydrogen 2.865 N/A MET 27.A N ALA 92.A O no hydrogen 3.064 N/A ALA 30.A N THR 33.A OG1 no hydrogen 3.171 N/A SER 31.A OG GLN 149.A O no hydrogen 2.309 N/A GLY 32.A N VAL 147.A O no hydrogen 2.985 N/A THR 33.A N ALA 30.A O no hydrogen 2.934 N/A THR 33.A OG1 ALA 30.A O no hydrogen 2.906 N/A VAL 34.A N TRP 139.A O no hydrogen 2.850 N/A SER 35.A N VAL 59.A O no hydrogen 3.074 N/A SER 36.A N ASN 137.A O no hydrogen 3.139 N/A SER 36.A OG ASN 137.A OD1 no hydrogen 2.823 N/A MET 37.A N ILE 57.A O no hydrogen 2.982 N/A PHE 38.A N ARG 135.A O no hydrogen 2.797 N/A LEU 39.A N VAL 55.A O no hydrogen 2.809 N/A TYR 40.A N GLY 133.A O no hydrogen 2.781 N/A TYR 40.A OH GLU 45.A OE1 no hydrogen 2.485 N/A GLN 41.A N VAL 53.A O no hydrogen 3.029 N/A ASN 42.A N GLU 15.A OE1 no hydrogen 2.688 N/A GLY 43.A N GLU 45.A OE1 no hydrogen 2.959 N/A SER 44.A N GLN 41.A O no hydrogen 3.065 N/A SER 44.A OG GLN 41.A O no hydrogen 2.974 N/A SER 44.A OG PRO 51.A O no hydrogen 3.533 N/A SER 44.A OG VAL 53.A O no hydrogen 3.448 N/A GLU 45.A N GLU 45.A OE1 no hydrogen 2.963 N/A ILE 46.A N GLY 43.A O no hydrogen 3.036 N/A ARG 50.A NE ASP 48.A O no hydrogen 3.368 N/A TRP 52.A N GLY 74.A O no hydrogen 2.740 N/A TRP 52.A NE1 GLU 54.A OE1 no hydrogen 2.897 N/A VAL 53.A N SER 44.A OG no hydrogen 2.761 N/A GLU 54.A N ILE 72.A O no hydrogen 3.123 N/A VAL 55.A N LEU 39.A O no hydrogen 3.124 N/A ASP 56.A N ASN 70.A O no hydrogen 3.086 N/A ILE 57.A N MET 37.A O no hydrogen 3.007 N/A GLU 58.A N GLN 68.A O no hydrogen 3.013 N/A VAL 59.A N SER 35.A O no hydrogen 2.811 N/A GLY 61.A N THR 33.A O no hydrogen 2.835 N/A LYS 62.A NZ TRP 146.A O no hydrogen 3.221 N/A ASN 63.A N LEU 60.A O no hydrogen 2.974 N/A SER 66.A N ASN 63.A O no hydrogen 3.028 N/A SER 66.A OG HIS 86.A O no hydrogen 2.718 N/A PHE 67.A N HIS 86.A O no hydrogen 2.831 N/A GLN 68.A N GLU 58.A O no hydrogen 2.933 N/A SER 69.A N LYS 84.A O no hydrogen 2.919 N/A SER 69.A OG HIS 86.A NE2 no hydrogen 2.502 N/A ILE 71.A N SER 82.A OG no hydrogen 3.272 N/A ILE 72.A N GLU 54.A O no hydrogen 2.964 N/A THR 73.A N LYS 80.A O no hydrogen 3.087 N/A ALA 78.A N LYS 75.A O no hydrogen 2.897 N/A LYS 80.A N THR 73.A O no hydrogen 2.866 N/A SER 82.A OG ILE 71.A O no hydrogen 3.416 N/A SER 82.A OG GLN 124.A OE1 no hydrogen 2.645 N/A LYS 84.A N SER 69.A O no hydrogen 3.146 N/A HIS 86.A N PHE 67.A O no hydrogen 2.859 N/A HIS 86.A NE2 SER 69.A OG no hydrogen 2.502 N/A VAL 88.A N GLY 65.A O no hydrogen 3.131 N/A ALA 92.A N PRO 64.A O no hydrogen 2.726 N/A GLN 94.A N ALA 91.A O no hydrogen 2.907 N/A GLN 94.A NE2 ASP 93.A OD1 no hydrogen 3.505 N/A HIS 97.A N MET 25.A O no hydrogen 2.967 N/A HIS 97.A ND1 ASP 113.A OD1 no hydrogen 2.661 N/A HIS 97.A NE2 PRO 90.A O no hydrogen 2.657 N/A THR 98.A N ASP 113.A OD2 no hydrogen 2.895 N/A TYR 99.A N ALA 23.A O no hydrogen 2.919 N/A GLY 100.A N THR 111.A O no hydrogen 2.729 N/A LEU 101.A N PHE 21.A O no hydrogen 2.906 N/A GLU 102.A N ARG 109.A O no hydrogen 2.925 N/A TRP 103.A N GLY 19.A O no hydrogen 2.945 N/A THR 104.A N TYR 107.A O no hydrogen 3.016 N/A ASN 106.A N THR 104.A OG1 no hydrogen 2.973 N/A TYR 107.A N THR 104.A OG1 no hydrogen 3.091 N/A TYR 107.A OH ASP 179.A OD1 no hydrogen 3.413 N/A VAL 108.A N THR 120.A O no hydrogen 2.920 N/A ARG 109.A N GLU 102.A O no hydrogen 2.855 N/A ARG 109.A NE GLU 116.A OE2 no hydrogen 2.984 N/A ARG 109.A NH1 GLU 102.A OE2 no hydrogen 3.230 N/A ARG 109.A NH2 GLU 116.A OE2 no hydrogen 3.495 N/A TRP 110.A N ARG 118.A O no hydrogen 2.846 N/A TRP 110.A NE1 ASP 56.A O no hydrogen 2.942 N/A THR 111.A N GLY 100.A O no hydrogen 2.881 N/A VAL 112.A N GLN 115.A O no hydrogen 2.945 N/A ASP 113.A N THR 98.A O no hydrogen 2.817 N/A GLN 115.A N VAL 112.A O no hydrogen 2.922 N/A GLN 115.A NE2 ASP 113.A O no hydrogen 3.202 N/A VAL 117.A N TRP 110.A O no hydrogen 3.100 N/A ARG 118.A NE THR 120.A OG1 no hydrogen 3.024 N/A ARG 118.A NH1 SER 69.A OG no hydrogen 2.832 N/A ARG 118.A NH1 SER 82.A O no hydrogen 2.757 N/A ARG 118.A NH2 SER 82.A O no hydrogen 3.477 N/A ARG 118.A NH2 SER 82.A OG no hydrogen 3.163 N/A ARG 118.A NH2 THR 120.A OG1 no hydrogen 3.250 N/A THR 120.A N VAL 108.A O no hydrogen 2.870 N/A GLY 122.A N ASN 106.A O no hydrogen 3.011 N/A GLN 124.A NE2 ILE 71.A O no hydrogen 3.194 N/A GLN 124.A NE2 THR 73.A OG1 no hydrogen 2.905 N/A GLN 124.A NE2 LYS 80.A O no hydrogen 2.852 N/A VAL 125.A N GLY 122.A O no hydrogen 2.971 N/A SER 126.A N GLY 123.A O no hydrogen 3.020 N/A ASN 127.A N GLN 124.A O no hydrogen 2.806 N/A LEU 128.A N VAL 125.A O no hydrogen 3.016 N/A THR 131.A OG1 GLU 15.A OE2 no hydrogen 2.917 N/A GLN 132.A N VAL 16.A O no hydrogen 2.851 N/A GLY 133.A N TYR 40.A O no hydrogen 2.684 N/A LEU 134.A N THR 12.A OG1 no hydrogen 3.011 N/A ARG 135.A N PHE 38.A O no hydrogen 2.745 N/A ARG 135.A NH1 GLU 9.A OE2 no hydrogen 2.896 N/A PHE 136.A N LEU 10.A O no hydrogen 2.968 N/A ASN 137.A N SER 36.A O no hydrogen 3.076 N/A ASN 137.A ND2 GLU 9.A OE1 no hydrogen 3.023 N/A LEU 138.A N ALA 8.A O no hydrogen 2.873 N/A TRP 139.A N VAL 34.A O no hydrogen 2.885 N/A SER 140.A OG GLY 32.A O no hydrogen 3.000 N/A SER 141.A N GLY 32.A O no hydrogen 3.200 N/A GLU 142.A N GLY 205.A O no hydrogen 3.015 N/A SER 143.A N SER 141.A OG no hydrogen 2.948 N/A TRP 146.A N SER 143.A O no hydrogen 2.911 N/A VAL 147.A N SER 143.A O no hydrogen 3.088 N/A GLY 148.A N ALA 144.A O no hydrogen 2.719 N/A ASP 151.A N SER 31.A O no hydrogen 3.319 N/A GLU 152.A N PHE 150.A O no hydrogen 3.049 N/A SER 153.A OG ASP 151.A OD2 no hydrogen 3.135 N/A LYS 154.A N ASP 151.A O no hydrogen 2.977 N/A LYS 154.A NZ ASP 151.A OD1 no hydrogen 3.201 N/A LEU 155.A N GLU 152.A O no hydrogen 3.234 N/A LEU 157.A N LEU 226.A O no hydrogen 2.840 N/A GLN 159.A N LEU 224.A O no hydrogen 2.893 N/A PHE 160.A N LYS 26.A O no hydrogen 2.806 N/A ILE 161.A N LEU 222.A O no hydrogen 2.835 N/A ASN 162.A N ARG 24.A O no hydrogen 2.821 N/A ASN 162.A ND2 ASP 241.A OD1 no hydrogen 3.044 N/A VAL 164.A N ASP 186.A O no hydrogen 3.045 N/A LYS 165.A N GLU 22.A O no hydrogen 2.944 N/A VAL 166.A N TRP 184.A O no hydrogen 2.958 N/A TYR 167.A N LYS 20.A O no hydrogen 2.911 N/A TYR 167.A OH GLU 22.A OE1 no hydrogen 2.754 N/A LYS 168.A N THR 181.A O no hydrogen 2.808 N/A THR 170.A N ASP 179.A O no hydrogen 2.679 N/A THR 170.A OG1 GLN 173.A O no hydrogen 3.082 N/A THR 170.A OG1 ASP 179.A O no hydrogen 3.539 N/A THR 170.A OG1 THR 181.A OG1 no hydrogen 2.737 N/A GLY 172.A N ASP 179.A OD2 no hydrogen 3.119 N/A GLN 173.A N THR 170.A O no hydrogen 2.696 N/A SER 178.A N GLU 175.A O no hydrogen 2.574 N/A SER 178.A OG GLU 175.A O no hydrogen 3.001 N/A THR 181.A N LYS 168.A O no hydrogen 2.965 N/A THR 181.A OG1 THR 170.A OG1 no hydrogen 2.737 N/A ASP 183.A N VAL 166.A O no hydrogen 2.780 N/A TRP 184.A N VAL 166.A O no hydrogen 3.131 N/A ASP 186.A N VAL 164.A O no hydrogen 2.762 N/A PHE 188.A N ASP 186.A OD1 no hydrogen 2.886 N/A THR 190.A OG1 PHE 191.A O no hydrogen 3.361 N/A SER 194.A N ASP 192.A OD1 no hydrogen 2.857 N/A SER 194.A OG ASP 192.A OD1 no hydrogen 2.518 N/A SER 194.A OG ASP 192.A OD2 no hydrogen 3.319 N/A ARG 195.A N ASP 192.A O no hydrogen 2.930 N/A TRP 196.A N ASP 192.A O no hydrogen 2.871 N/A TRP 196.A NE1 ASP 186.A OD2 no hydrogen 2.706 N/A GLY 197.A N TYR 11.A O no hydrogen 2.728 N/A LYS 198.A NZ ASP 212.A O no hydrogen 3.000 N/A LYS 198.A NZ ILE 215.A O no hydrogen 2.869 N/A GLY 199.A N GLU 9.A O no hydrogen 2.654 N/A TRP 201.A N LEU 210.A O no hydrogen 2.932 N/A THR 202.A OG1 VAL 208.A O no hydrogen 2.681 N/A PHE 203.A N THR 202.A OG1 no hydrogen 2.644 N/A ASN 206.A N PHE 203.A O no hydrogen 2.883 N/A ARG 207.A N SER 140.A O no hydrogen 3.019 N/A ARG 207.A NE SER 141.A O no hydrogen 3.168 N/A VAL 208.A N ASN 206.A OD1 no hydrogen 2.999 N/A ASP 209.A N PHE 5.A O no hydrogen 3.033 N/A LEU 210.A N TRP 201.A O no hydrogen 2.734 N/A THR 211.A N GLY 7.A O no hydrogen 3.132 N/A THR 211.A OG1 ASN 214.A OD1 no hydrogen 2.596 N/A ASP 212.A N ASP 200.A OD2 no hydrogen 2.939 N/A LYS 213.A N THR 211.A OG1 no hydrogen 3.264 N/A ASN 214.A N THR 211.A O no hydrogen 3.035 N/A ASN 214.A ND2 SER 6.A OG no hydrogen 2.986 N/A ASN 214.A ND2 ALA 225.A O no hydrogen 2.667 N/A TYR 216.A N ILE 223.A O no hydrogen 3.183 N/A TYR 216.A OH GLU 232.A O no hydrogen 2.756 N/A SER 217.A OG PHE 188.A O no hydrogen 2.990 N/A ARG 218.A N MET 221.A O no hydrogen 2.758 N/A ARG 218.A NH1 PHE 234.A O no hydrogen 3.129 N/A ARG 218.A NH2 PHE 234.A O no hydrogen 2.529 N/A MET 221.A N ARG 218.A O no hydrogen 3.055 N/A LEU 222.A N ILE 161.A O no hydrogen 2.736 N/A ILE 223.A N TYR 216.A O no hydrogen 2.817 N/A LEU 224.A N GLN 159.A O no hydrogen 3.021 N/A ALA 225.A N ASN 214.A O no hydrogen 2.782 N/A LEU 226.A N LEU 157.A O no hydrogen 2.934 N/A THR 227.A N SER 6.A O no hydrogen 3.145 N/A THR 227.A OG1 ARG 228.A O no hydrogen 2.908 N/A LYS 229.A N ASP 4.A O no hydrogen 2.838 N/A LYS 229.A NZ ASP 209.A OD1 no hydrogen 2.521 N/A GLY 230.A N GLU 232.A OE1 no hydrogen 3.138 N/A GLN 231.A N ARG 228.A O no hydrogen 2.942 N/A GLU 232.A N GLU 232.A OE2 no hydrogen 2.550 N/A PHE 234.A N TYR 216.A OH no hydrogen 2.749 N/A ARG 240.A NH2 VAL 238.A O no hydrogen 3.347 N/A