Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2r6d_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 7.A N SER 4.A OG no hydrogen 3.330 N/A GLU 8.A N SER 4.A O no hydrogen 2.924 N/A GLN 9.A N ILE 5.A O no hydrogen 2.820 N/A GLN 9.A NE2 TYR 79.A OH no hydrogen 3.368 N/A ALA 10.A N GLU 6.A O no hydrogen 3.450 N/A VAL 11.A N ALA 7.A O no hydrogen 3.190 N/A LEU 12.A N GLU 8.A O no hydrogen 3.042 N/A GLY 13.A N GLN 9.A O no hydrogen 2.848 N/A ALA 14.A N ALA 10.A O no hydrogen 2.486 N/A VAL 15.A N VAL 11.A O no hydrogen 3.012 N/A LEU 17.A N GLY 13.A O no hydrogen 3.213 N/A ASP 18.A N VAL 15.A O no hydrogen 3.080 N/A LEU 22.A N PRO 19.A O no hydrogen 3.087 N/A ALA 25.A N ALA 21.A O no hydrogen 3.180 N/A SER 26.A N LEU 22.A O no hydrogen 3.235 N/A SER 26.A OG VAL 23.A O no hydrogen 3.130 N/A GLU 27.A N VAL 23.A O no hydrogen 3.273 N/A ILE 28.A N ALA 25.A O no hydrogen 3.012 N/A LEU 29.A N ALA 25.A O no hydrogen 2.877 N/A ILE 30.A N ASP 33.A OD2 no hydrogen 2.699 N/A GLU 32.A N GLU 32.A OE1 no hydrogen 2.343 N/A ASP 33.A N ILE 30.A O no hydrogen 2.699 N/A PHE 34.A N PRO 31.A O no hydrogen 2.797 N/A TYR 35.A N GLU 8.A OE2 no hydrogen 2.569 N/A GLN 40.A N ARG 36.A O no hydrogen 3.041 N/A LYS 41.A N ALA 37.A O no hydrogen 3.156 N/A LYS 41.A NZ GLU 73.A OE2 no hydrogen 2.539 N/A ILE 42.A N ALA 38.A O no hydrogen 3.357 N/A PHE 43.A N HIS 39.A O no hydrogen 3.027 N/A HIS 44.A N GLN 40.A O no hydrogen 3.143 N/A ALA 45.A N LYS 41.A O no hydrogen 2.879 N/A MET 46.A N ILE 42.A O no hydrogen 2.648 N/A LEU 47.A N PHE 43.A O no hydrogen 2.892 N/A ARG 48.A N HIS 44.A O no hydrogen 2.747 N/A VAL 49.A N ALA 45.A O no hydrogen 2.981 N/A VAL 49.A N MET 46.A O no hydrogen 3.346 N/A ALA 50.A N MET 46.A O no hydrogen 3.426 N/A ASP 51.A N LEU 47.A O no hydrogen 3.362 N/A ARG 52.A N VAL 49.A O no hydrogen 2.956 N/A ARG 52.A NH1 GLU 54.A OE1 no hydrogen 3.186 N/A ARG 52.A NH1 GLU 64.A OE1 no hydrogen 2.716 N/A THR 60.A N ASP 57.A OD1 no hydrogen 3.350 N/A THR 60.A OG1 PRO 55.A O no hydrogen 3.315 N/A VAL 61.A N ASP 57.A O no hydrogen 3.193 N/A THR 62.A N LEU 58.A O no hydrogen 3.115 N/A THR 62.A OG1 VAL 59.A O no hydrogen 3.156 N/A ALA 63.A N VAL 59.A O no hydrogen 2.921 N/A GLU 64.A N THR 60.A O no hydrogen 3.316 N/A LEU 65.A N VAL 61.A O no hydrogen 3.188 N/A LEU 65.A N THR 62.A O no hydrogen 3.256 N/A ALA 66.A N THR 62.A O no hydrogen 3.018 N/A ALA 67.A N ALA 63.A O no hydrogen 3.002 N/A SER 68.A N GLU 64.A O no hydrogen 3.392 N/A SER 68.A OG GLU 64.A O no hydrogen 3.161 N/A GLU 69.A N ALA 66.A O no hydrogen 3.031 N/A GLN 70.A N LEU 65.A O no hydrogen 2.704 N/A ILE 74.A N LEU 71.A O no hydrogen 3.000 N/A TYR 79.A N GLY 76.A O no hydrogen 3.295 N/A TYR 79.A OH HIS 39.A NE2 no hydrogen 2.749 N/A SER 81.A N VAL 77.A O no hydrogen 2.913 N/A SER 81.A OG VAL 77.A O no hydrogen 3.398 N/A GLU 82.A N SER 78.A O no hydrogen 3.006 N/A LEU 83.A N TYR 79.A O no hydrogen 3.008 N/A ALA 84.A N LEU 80.A O no hydrogen 3.414 N/A ASP 85.A N GLU 82.A O no hydrogen 2.614 N/A THR 89.A OG1 TYR 96.A OH no hydrogen 3.302 N/A ASN 92.A N THR 89.A O no hydrogen 3.248 N/A ASN 92.A ND2 THR 89.A OG1 no hydrogen 2.818 N/A VAL 93.A N ALA 90.A O no hydrogen 3.402 N/A TYR 95.A N ASN 92.A O no hydrogen 3.111 N/A TYR 96.A N ASN 92.A O no hydrogen 3.215 N/A TYR 96.A OH THR 89.A OG1 no hydrogen 3.302 N/A ALA 97.A N VAL 93.A O no hydrogen 2.919 N/A ARG 98.A N GLU 94.A O no hydrogen 3.026 N/A ARG 98.A NH2 GLU 94.A OE1 no hydrogen 3.407 N/A ILE 99.A N TYR 95.A O no hydrogen 3.221 N/A VAL 100.A N TYR 96.A O no hydrogen 3.298 N/A GLU 101.A N ALA 97.A O no hydrogen 2.777 N/A GLU 102.A N ARG 98.A O no hydrogen 2.750 N/A LYS 103.A N ILE 99.A O no hydrogen 3.176 N/A SER 104.A N GLU 101.A O no hydrogen 2.975 N/A SER 104.A OG ASP 33.A OD1 no hydrogen 2.970 N/A VAL 105.A N GLU 101.A O no hydrogen 3.106 N/A LEU 106.A N GLU 102.A O no hydrogen 3.125 N/A ARG 107.A N LYS 103.A O no hydrogen 3.289 N/A ARG 107.A NH1 PRO 2.A O no hydrogen 3.141 N/A ARG 107.A NH2 GLU 32.A O no hydrogen 3.537 N/A ARG 107.A NH2 ASP 33.A O no hydrogen 2.792 N/A LEU 109.A N VAL 105.A O no hydrogen 2.763 N/A ILE 110.A N LEU 106.A O no hydrogen 2.910 N/A ARG 111.A N ARG 107.A O no hydrogen 2.887 N/A THR 112.A N ARG 108.A O no hydrogen 2.875 N/A THR 112.A OG1 ARG 108.A O no hydrogen 3.063 N/A THR 112.A OG1 LEU 109.A O no hydrogen 3.214 N/A ALA 113.A N LEU 109.A O no hydrogen 2.810 N/A THR 114.A N ILE 110.A O no hydrogen 2.810 N/A THR 114.A OG1 ILE 110.A O no hydrogen 2.817 N/A SER 115.A N ARG 111.A O no hydrogen 2.729 N/A ILE 116.A N ALA 113.A O no hydrogen 2.914 N/A ALA 117.A N ALA 113.A O no hydrogen 3.089 N/A GLN 118.A N THR 114.A O no hydrogen 2.793 N/A GLN 118.A NE2 GLN 118.A O no hydrogen 3.248 N/A ASP 119.A N ILE 116.A O no hydrogen 2.925 N/A GLY 120.A N ILE 116.A O no hydrogen 3.136 N/A GLY 120.A N ALA 117.A O no hydrogen 2.984 N/A THR 122.A N ASP 119.A O no hydrogen 3.235 N/A THR 122.A OG1 ASP 119.A O no hydrogen 3.524 N/A ARG 123.A N ASP 119.A O no hydrogen 3.225 N/A ARG 123.A NH1 GLU 126.A OE1 no hydrogen 2.672 N/A LEU 131.A N ILE 127.A O no hydrogen 2.761 N/A ASP 132.A N VAL 129.A O no hydrogen 2.849 N/A GLU 133.A N VAL 129.A O no hydrogen 2.801 N/A ALA 134.A N LEU 130.A O no hydrogen 2.800 N/A ARG 136.A N ASP 132.A O no hydrogen 3.310 N/A LYS 137.A N GLU 133.A O no hydrogen 3.030 N/A ILE 138.A N ALA 134.A O no hydrogen 3.420 N/A MET 139.A N ASP 135.A O no hydrogen 2.750 N/A VAL 141.A N ILE 138.A O no hydrogen 2.944 N/A GLN 143.A N MET 139.A O no hydrogen 3.427 N/A LYS 150.A N ASN 148.A OD1 no hydrogen 3.157 N/A ASP 151.A N ASN 148.A O no hydrogen 3.343 N/A LEU 153.A N ILE 149.A O no hydrogen 3.186 N/A VAL 154.A N ASP 151.A O no hydrogen 2.782 N/A GLN 155.A N ASP 151.A O no hydrogen 3.052 N/A THR 156.A N ILE 152.A O no hydrogen 2.997 N/A THR 156.A OG1 ILE 152.A O no hydrogen 2.549 N/A ASP 158.A N VAL 154.A O no hydrogen 2.977 N/A ASN 159.A N GLN 155.A O no hydrogen 2.739 N/A GLU 161.A N TYR 157.A O no hydrogen 3.098 N/A GLU 161.A N ASP 158.A O no hydrogen 3.360 N/A MET 162.A N ASP 158.A O no hydrogen 3.323 N/A HIS 164.A N GLU 161.A O no hydrogen 2.424 N/A ASN 165.A N GLU 161.A O no hydrogen 3.103 N/A ASN 165.A ND2 GLU 161.A OE1 no hydrogen 2.730 N/A ARG 166.A N MET 162.A O no hydrogen 3.108 N/A ARG 166.A NE ARG 182.A O no hydrogen 2.729 N/A GLY 172.A N SER 185.A O no hydrogen 2.772 N/A ILE 173.A N PHE 187.A O no hydrogen 2.937 N/A THR 175.A N ASP 181.A OD1 no hydrogen 2.884 N/A THR 175.A N ASP 181.A OD2 no hydrogen 3.133 N/A THR 175.A OG1 ASP 181.A OD1 no hydrogen 2.321 N/A ASP 181.A N PHE 177.A O no hydrogen 2.996 N/A ARG 182.A N THR 178.A O no hydrogen 3.341 N/A THR 184.A N LEU 180.A O no hydrogen 3.048 N/A THR 184.A OG1 LEU 180.A O no hydrogen 2.841 N/A PHE 187.A N ILE 173.A O no hydrogen 3.332 N/A ASP 191.A N GLN 188.A O no hydrogen 3.279 N/A LEU 192.A N ASP 366.A OD1 no hydrogen 2.632 N/A ILE 193.A N VAL 337.A O no hydrogen 2.786 N/A ILE 194.A N ILE 367.A O no hydrogen 2.896 N/A VAL 195.A N ALA 339.A O no hydrogen 3.103 N/A ALA 196.A N ALA 369.A O no hydrogen 2.774 N/A ALA 197.A N SER 341.A O no hydrogen 3.178 N/A VAL 201.A N ARG 198.A O no hydrogen 3.185 N/A LYS 203.A NZ GLN 342.A OE1 no hydrogen 3.102 N/A PHE 206.A N GLY 202.A O no hydrogen 2.973 N/A ALA 207.A N LYS 203.A O no hydrogen 2.779 N/A LEU 208.A N THR 204.A O no hydrogen 2.882 N/A ASN 209.A N ALA 205.A O no hydrogen 2.870 N/A ILE 210.A N PHE 206.A O no hydrogen 3.353 N/A ALA 211.A N ALA 207.A O no hydrogen 2.945 N/A GLN 212.A N LEU 208.A O no hydrogen 2.747 N/A ASN 213.A N ASN 209.A O no hydrogen 2.814 N/A VAL 214.A N ILE 210.A O no hydrogen 2.748 N/A ALA 215.A N ALA 211.A O no hydrogen 2.988 N/A THR 216.A N GLN 212.A O no hydrogen 2.971 N/A THR 216.A OG1 GLN 212.A O no hydrogen 2.766 N/A LYS 217.A N ASN 213.A O no hydrogen 3.275 N/A THR 218.A N VAL 214.A O no hydrogen 3.165 N/A ASN 221.A ND2 GLY 300.A O no hydrogen 2.740 N/A VAL 222.A N GLY 274.A O no hydrogen 2.960 N/A ALA 223.A N MET 303.A O no hydrogen 2.757 N/A ILE 224.A N TYR 276.A O no hydrogen 2.824 N/A PHE 225.A N VAL 305.A O no hydrogen 2.676 N/A SER 226.A N ASP 278.A O no hydrogen 2.993 N/A SER 226.A OG MET 229.A O no hydrogen 2.721 N/A MET 229.A N SER 226.A OG no hydrogen 3.171 N/A SER 230.A OG GLN 233.A OE1 no hydrogen 3.141 N/A ALA 231.A N ASP 279.A OD2 no hydrogen 3.083 N/A LEU 234.A N SER 230.A O no hydrogen 2.870 N/A VAL 235.A N ALA 231.A O no hydrogen 2.987 N/A MET 236.A N GLN 232.A O no hydrogen 2.999 N/A ARG 237.A N LEU 234.A O no hydrogen 2.961 N/A MET 238.A N LEU 234.A O no hydrogen 3.258 N/A LEU 239.A N VAL 235.A O no hydrogen 2.768 N/A CYS 240.A N MET 236.A O no hydrogen 3.360 N/A CYS 240.A SG MET 236.A O no hydrogen 2.723 N/A ALA 241.A N ARG 237.A O no hydrogen 3.014 N/A GLU 242.A N LEU 239.A O no hydrogen 3.160 N/A GLY 243.A N LEU 239.A O no hydrogen 3.198 N/A ILE 245.A N CYS 240.A O no hydrogen 3.114 N/A ALA 247.A N GLU 398.A O no hydrogen 2.731 N/A LEU 250.A N ASN 246.A O no hydrogen 3.334 N/A LEU 250.A N ALA 247.A O no hydrogen 3.140 N/A ARG 251.A N ALA 247.A O no hydrogen 3.159 N/A THR 252.A N GLN 248.A O no hydrogen 3.008 N/A THR 252.A OG1 GLN 248.A O no hydrogen 3.303 N/A GLY 253.A N LEU 250.A O no hydrogen 3.071 N/A TRP 260.A N THR 256.A O no hydrogen 2.644 N/A GLY 261.A N PRO 257.A O no hydrogen 3.298 N/A LYS 262.A NZ ASN 244.A O no hydrogen 3.156 N/A LEU 263.A N ASP 259.A O no hydrogen 3.289 N/A LEU 263.A N TRP 260.A O no hydrogen 3.204 N/A THR 264.A OG1 GLY 261.A O no hydrogen 2.929 N/A ALA 266.A N LYS 262.A O no hydrogen 3.406 N/A MET 267.A N LEU 263.A O no hydrogen 2.892 N/A GLY 268.A N THR 264.A O no hydrogen 3.289 N/A SER 269.A N MET 265.A O no hydrogen 3.135 N/A SER 269.A OG GLU 242.A OE1 no hydrogen 3.171 N/A SER 269.A OG MET 265.A O no hydrogen 2.805 N/A SER 269.A OG ALA 266.A O no hydrogen 2.736 N/A LEU 270.A N ALA 266.A O no hydrogen 2.899 N/A SER 271.A N MET 267.A O no hydrogen 2.679 N/A SER 271.A N GLY 268.A O no hydrogen 2.854 N/A SER 271.A OG MET 267.A O no hydrogen 2.718 N/A SER 271.A OG GLY 268.A O no hydrogen 3.536 N/A ALA 273.A N LEU 270.A O no hydrogen 3.379 N/A TYR 276.A N VAL 222.A O no hydrogen 3.055 N/A ASP 278.A N ILE 224.A O no hydrogen 2.919 N/A THR 280.A N ASP 278.A OD2 no hydrogen 3.012 N/A THR 280.A OG1 ASP 278.A OD1 no hydrogen 3.474 N/A THR 280.A OG1 ASP 278.A OD2 no hydrogen 2.581 N/A ARG 284.A NE GLY 314.A O no hydrogen 3.208 N/A ARG 284.A NH2 GLY 316.A O no hydrogen 2.358 N/A ILE 288.A N ARG 284.A O no hydrogen 3.416 N/A ARG 289.A N VAL 285.A O no hydrogen 2.826 N/A ALA 290.A N SER 286.A O no hydrogen 3.088 N/A LYS 291.A N ASP 287.A O no hydrogen 3.212 N/A LYS 291.A NZ ASP 278.A OD1 no hydrogen 2.862 N/A CYS 292.A N ILE 288.A O no hydrogen 3.147 N/A CYS 292.A SG ILE 288.A O no hydrogen 3.189 N/A ARG 293.A N ARG 289.A O no hydrogen 2.837 N/A ARG 294.A N ALA 290.A O no hydrogen 3.248 N/A LEU 295.A N LYS 291.A O no hydrogen 3.183 N/A LYS 296.A N CYS 292.A O no hydrogen 3.013 N/A LYS 296.A NZ LEU 333.A O no hydrogen 3.199 N/A GLU 298.A N LEU 295.A O no hydrogen 3.372 N/A SER 299.A N LEU 295.A O no hydrogen 2.976 N/A GLY 300.A N LEU 295.A O no hydrogen 3.113 N/A GLY 302.A N ASN 221.A O no hydrogen 2.908 N/A MET 303.A N ASN 221.A O no hydrogen 3.264 N/A ILE 304.A N PRO 336.A O no hydrogen 3.207 N/A VAL 305.A N ALA 223.A O no hydrogen 2.930 N/A ILE 306.A N ILE 338.A O no hydrogen 2.842 N/A ASP 307.A N PHE 225.A O no hydrogen 2.690 N/A TYR 308.A OH GLU 228.A OE2 no hydrogen 3.367 N/A LEU 309.A N LEU 340.A O no hydrogen 2.876 N/A LEU 311.A N TYR 308.A O no hydrogen 3.287 N/A ILE 312.A N LEU 309.A O no hydrogen 2.766 N/A GLN 313.A N ILE 283.A O no hydrogen 3.096 N/A GLN 313.A NE2 SER 282.A O no hydrogen 3.615 N/A ILE 322.A N GLU 318.A O no hydrogen 3.238 N/A SER 323.A N VAL 319.A O no hydrogen 3.009 N/A SER 323.A OG ASP 364.A OD2 no hydrogen 3.124 N/A ARG 324.A N SER 320.A O no hydrogen 2.787 N/A SER 325.A N GLU 321.A O no hydrogen 2.928 N/A LEU 326.A N ILE 322.A O no hydrogen 2.914 N/A LYS 327.A N SER 323.A O no hydrogen 3.124 N/A LYS 327.A NZ SER 190.A O no hydrogen 2.812 N/A LYS 327.A NZ ASP 366.A OD2 no hydrogen 2.714 N/A ALA 328.A N ARG 324.A O no hydrogen 3.129 N/A LEU 329.A N SER 325.A O no hydrogen 2.747 N/A ALA 330.A N LEU 326.A O no hydrogen 3.018 N/A ARG 331.A N LYS 327.A O no hydrogen 2.994 N/A GLU 332.A N ALA 328.A O no hydrogen 2.874 N/A LEU 333.A N LEU 329.A O no hydrogen 3.097 N/A VAL 335.A N ALA 330.A O no hydrogen 3.294 N/A VAL 337.A N ASP 191.A O no hydrogen 3.016 N/A ILE 338.A N ILE 304.A O no hydrogen 2.757 N/A ALA 339.A N ILE 193.A O no hydrogen 2.836 N/A LEU 340.A N ILE 306.A O no hydrogen 3.121 N/A SER 341.A N VAL 195.A O no hydrogen 2.721 N/A SER 341.A OG GLN 342.A O no hydrogen 3.448 N/A SER 344.A N ASP 354.A O no hydrogen 3.412 N/A SER 344.A OG SER 346.A OG no hydrogen 3.335 N/A SER 344.A OG ASP 354.A O no hydrogen 2.825 N/A SER 346.A OG SER 344.A OG no hydrogen 3.335 N/A ARG 349.A NH1 GLU 377.A OE1 no hydrogen 2.827 N/A ARG 349.A NH2 GLU 377.A OE1 no hydrogen 3.320 N/A MET 351.A N ASP 354.A OD2 no hydrogen 2.797 N/A SER 353.A OG ASP 354.A OD1 no hydrogen 3.430 N/A ASP 354.A N MET 351.A O no hydrogen 3.005 N/A ILE 355.A N MET 352.A O no hydrogen 3.299 N/A ARG 356.A N MET 352.A O no hydrogen 3.077 N/A ARG 356.A NH1 SER 360.A OG no hydrogen 2.539 N/A GLU 357.A N SER 353.A O no hydrogen 3.267 N/A SER 358.A N ILE 355.A O no hydrogen 3.074 N/A GLY 359.A N ARG 356.A O no hydrogen 3.294 N/A SER 360.A N SER 320.A OG no hydrogen 2.813 N/A GLN 363.A N SER 360.A O no hydrogen 3.426 N/A ALA 365.A N ILE 361.A O no hydrogen 3.023 N/A ASP 366.A N LEU 192.A O no hydrogen 3.355 N/A VAL 368.A N LYS 382.A O no hydrogen 2.992 N/A ALA 369.A N ILE 194.A O no hydrogen 2.697 N/A PHE 370.A N ILE 379.A O no hydrogen 2.716 N/A LEU 371.A N ALA 196.A O no hydrogen 3.090 N/A TYR 372.A N GLU 377.A O no hydrogen 2.803 N/A ASN 374.A ND2 PHE 395.A O no hydrogen 2.762 N/A ILE 376.A N LEU 393.A O no hydrogen 2.774 N/A ILE 378.A N VAL 391.A O no hydrogen 2.764 N/A ILE 379.A N PHE 370.A O no hydrogen 3.000 N/A ILE 380.A N GLY 389.A O no hydrogen 2.701 N/A ALA 381.A N VAL 368.A O no hydrogen 3.263 N/A LYS 382.A NZ GLU 362.A O no hydrogen 2.761 N/A LYS 382.A NZ ALA 365.A O no hydrogen 3.316 N/A GLN 383.A NE2 MET 183.A O no hydrogen 3.466 N/A GLN 383.A NE2 PRO 387.A O no hydrogen 3.009 N/A ARG 384.A N ASP 366.A O no hydrogen 2.942 N/A ARG 384.A NH1 GLN 363.A O no hydrogen 3.259 N/A GLY 389.A N ILE 380.A O no hydrogen 3.187 N/A VAL 391.A N ILE 378.A O no hydrogen 2.857 N/A LEU 393.A N ILE 376.A O no hydrogen 3.115 N/A ALA 394.A N VAL 403.A O no hydrogen 3.042 N/A PHE 395.A N ASN 374.A O no hydrogen 2.844 N/A ILE 396.A N LYS 401.A O no hydrogen 2.910 N/A ASN 400.A N ILE 396.A O no hydrogen 2.874 N/A LYS 401.A N ILE 396.A O no hydrogen 3.255 N/A LYS 401.A NZ ASN 244.A OD1 no hydrogen 2.786 N/A PHE 402.A N ASN 209.A OD1 no hydrogen 2.590 N/A VAL 403.A N ALA 394.A O no hydrogen 2.822 N/A ASN 404.A ND2 GLY 176.A O no hydrogen 3.495 N/A