Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2v1u_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 3.A OG GLU 252.A OE2 no hydrogen 2.284 N/A ILE 5.A N SER 3.A OG no hydrogen 2.921 N/A PHE 6.A N SER 3.A OG no hydrogen 3.148 N/A ARG 7.A N ALA 212.A O no hydrogen 2.594 N/A ARG 7.A NE GLU 211.A O no hydrogen 3.008 N/A LYS 8.A N ALA 212.A O no hydrogen 2.762 N/A LEU 12.A N ARG 9.A O no hydrogen 2.683 N/A LEU 13.A N TRP 10.A O no hydrogen 2.516 N/A TYR 16.A OH GLU 211.A OE2 no hydrogen 2.676 N/A HIS 23.A N GLU 25.A OE2 no hydrogen 2.645 N/A ARG 24.A N LEU 21.A O no hydrogen 3.465 N/A ARG 24.A NE TYR 196.A OH no hydrogen 2.722 N/A ARG 24.A NH1 PRO 194.A O no hydrogen 2.511 N/A GLU 27.A N GLU 27.A OE2 no hydrogen 2.302 N/A LEU 28.A N ARG 24.A O no hydrogen 3.290 N/A ARG 29.A N GLU 25.A O no hydrogen 2.596 N/A ARG 30.A N ALA 26.A O no hydrogen 2.773 N/A LEU 31.A N GLU 27.A O no hydrogen 3.353 N/A ALA 32.A N LEU 28.A O no hydrogen 3.104 N/A GLU 33.A N ARG 29.A O no hydrogen 2.806 N/A LEU 35.A N ALA 32.A O no hydrogen 3.395 N/A ALA 36.A N ALA 32.A O no hydrogen 2.972 N/A ALA 38.A N LEU 35.A O no hydrogen 3.198 N/A LEU 39.A N ALA 36.A O no hydrogen 2.565 N/A LYS 43.A NZ PRO 44.A O no hydrogen 2.753 N/A LYS 43.A NZ VAL 163.A O no hydrogen 2.744 N/A ALA 47.A N LEU 165.A O no hydrogen 3.007 N/A LEU 48.A N VAL 189.A O no hydrogen 3.040 N/A LEU 49.A N GLY 167.A O no hydrogen 2.882 N/A THR 53.A OG1 HIS 234.A NE2 no hydrogen 3.304 N/A THR 55.A N LEU 52.A O no hydrogen 3.253 N/A THR 55.A OG1 LEU 52.A O no hydrogen 2.407 N/A THR 58.A OG1 ASP 137.A OD2 no hydrogen 2.851 N/A VAL 60.A N GLY 56.A O no hydrogen 3.234 N/A ALA 61.A N LYS 57.A O no hydrogen 3.117 N/A ARG 62.A N THR 58.A O no hydrogen 3.044 N/A LEU 63.A N ALA 59.A O no hydrogen 3.056 N/A VAL 64.A N VAL 60.A O no hydrogen 2.853 N/A LEU 65.A N ALA 61.A O no hydrogen 2.847 N/A ARG 66.A N ARG 62.A O no hydrogen 2.850 N/A ARG 66.A NH2 VAL 17.A O no hydrogen 2.704 N/A ARG 67.A N LEU 63.A O no hydrogen 2.926 N/A LEU 68.A N VAL 64.A O no hydrogen 2.723 N/A GLU 69.A N LEU 65.A O no hydrogen 3.231 N/A GLU 69.A N ARG 66.A O no hydrogen 3.082 N/A ALA 70.A N ARG 66.A O no hydrogen 2.899 N/A ARG 71.A N ARG 67.A O no hydrogen 2.995 N/A ALA 72.A N LEU 68.A O no hydrogen 3.361 N/A SER 73.A N GLU 69.A O no hydrogen 2.784 N/A SER 73.A OG GLU 69.A O no hydrogen 2.623 N/A SER 74.A N ARG 71.A O no hydrogen 2.634 N/A LEU 75.A N ARG 71.A O no hydrogen 2.604 N/A GLY 76.A N ALA 72.A O no hydrogen 2.666 N/A LYS 80.A N ILE 131.A O no hydrogen 3.152 N/A ILE 82.A N ILE 133.A O no hydrogen 2.852 N/A TYR 83.A OH ASP 137.A OD2 no hydrogen 2.724 N/A VAL 84.A N VAL 135.A O no hydrogen 2.809 N/A ALA 86.A N ASP 137.A O no hydrogen 2.992 N/A ARG 87.A NE GLU 138.A OE1 no hydrogen 3.217 N/A HIS 88.A N ASN 85.A OD1 no hydrogen 2.634 N/A TYR 93.A OH PRO 108.A O no hydrogen 2.723 N/A VAL 95.A N THR 91.A O no hydrogen 3.048 N/A ALA 96.A N PRO 92.A O no hydrogen 3.288 N/A SER 97.A N TYR 93.A O no hydrogen 2.796 N/A ALA 98.A N ARG 94.A O no hydrogen 2.605 N/A ILE 99.A N VAL 95.A O no hydrogen 3.206 N/A ALA 100.A N ALA 96.A O no hydrogen 2.775 N/A GLU 101.A N SER 97.A O no hydrogen 3.366 N/A ALA 102.A N ALA 98.A O no hydrogen 3.460 N/A VAL 103.A N ALA 100.A O no hydrogen 2.843 N/A GLY 104.A N ALA 100.A O no hydrogen 3.338 N/A VAL 117.A N SER 113.A O no hydrogen 3.216 N/A TYR 118.A N VAL 114.A O no hydrogen 2.830 N/A GLU 119.A N GLY 115.A O no hydrogen 2.763 N/A ARG 120.A N GLU 116.A O no hydrogen 3.159 N/A LEU 121.A N VAL 117.A O no hydrogen 3.223 N/A VAL 122.A N TYR 118.A O no hydrogen 3.261 N/A LYS 123.A N ARG 120.A O no hydrogen 3.216 N/A ARG 124.A N ARG 120.A O no hydrogen 3.344 N/A LEU 125.A N LEU 121.A O no hydrogen 2.938 N/A SER 126.A N VAL 122.A O no hydrogen 2.850 N/A LEU 128.A N LEU 125.A O no hydrogen 3.227 N/A ILE 133.A N LYS 80.A O no hydrogen 2.820 N/A ILE 134.A N SER 164.A O no hydrogen 2.828 N/A VAL 135.A N ILE 82.A O no hydrogen 2.908 N/A LEU 136.A N VAL 166.A O no hydrogen 2.872 N/A ASP 137.A N VAL 84.A O no hydrogen 2.913 N/A GLU 138.A N ILE 168.A O no hydrogen 2.377 N/A ILE 139.A N ILE 168.A O no hydrogen 2.935 N/A LYS 144.A N ASP 140.A O no hydrogen 3.122 N/A ARG 145.A N LEU 142.A O no hydrogen 3.040 N/A GLY 148.A N ARG 145.A O no hydrogen 2.798 N/A GLN 149.A NE2 ASN 177.A O no hydrogen 3.085 N/A LEU 151.A N GLY 147.A O no hydrogen 2.787 N/A LEU 152.A N GLY 148.A O no hydrogen 3.236 N/A TYR 153.A N GLN 149.A O no hydrogen 3.276 N/A ARG 154.A N ASP 150.A O no hydrogen 3.043 N/A ILE 155.A N LEU 151.A O no hydrogen 2.849 N/A THR 156.A N LEU 152.A O no hydrogen 3.076 N/A THR 156.A OG1 SER 185.A OG no hydrogen 2.430 N/A ARG 157.A N TYR 153.A O no hydrogen 2.943 N/A ARG 157.A N ARG 154.A O no hydrogen 2.528 N/A ARG 157.A NH2 TYR 118.A OH no hydrogen 2.703 N/A ILE 158.A N ILE 155.A O no hydrogen 3.193 N/A GLN 160.A N ARG 157.A O no hydrogen 3.016 N/A GLU 161.A N ILE 158.A O no hydrogen 3.133 N/A SER 164.A N TYR 132.A O no hydrogen 3.153 N/A SER 164.A OG PRO 44.A O no hydrogen 3.443 N/A SER 164.A OG ASN 46.A OD1 no hydrogen 3.411 N/A LEU 165.A N ASN 46.A OD1 no hydrogen 2.089 N/A VAL 166.A N ILE 134.A O no hydrogen 2.704 N/A GLY 167.A N ALA 47.A O no hydrogen 2.882 N/A ILE 168.A N LEU 136.A O no hydrogen 3.170 N/A THR 169.A N LEU 49.A O no hydrogen 3.073 N/A THR 169.A OG1 ASP 140.A OD1 no hydrogen 1.900 N/A ASN 170.A N THR 169.A OG1 no hydrogen 2.335 N/A PHE 174.A N LEU 172.A O no hydrogen 2.322 N/A VAL 175.A N LEU 172.A O no hydrogen 2.944 N/A LEU 178.A N PHE 174.A O no hydrogen 3.145 N/A LYS 183.A N GLU 179.A O no hydrogen 2.636 N/A LYS 183.A NZ VAL 175.A O no hydrogen 3.537 N/A SER 184.A N ARG 181.A O no hydrogen 2.831 N/A SER 184.A OG PRO 180.A O no hydrogen 2.216 N/A SER 184.A OG ARG 181.A O no hydrogen 2.275 N/A SER 185.A N VAL 182.A O no hydrogen 3.237 N/A SER 185.A OG THR 156.A OG1 no hydrogen 2.430 N/A LEU 186.A N VAL 182.A O no hydrogen 3.003 N/A VAL 189.A N ASN 46.A O no hydrogen 3.082 N/A LEU 191.A N LEU 48.A O no hydrogen 2.583 N/A PHE 193.A N TYR 50.A O no hydrogen 3.427 N/A TYR 196.A OH THR 55.A O no hydrogen 2.691 N/A GLN 200.A N THR 197.A O no hydrogen 3.004 N/A LEU 201.A N THR 197.A O no hydrogen 3.244 N/A ARG 202.A N ALA 198.A O no hydrogen 2.793 N/A ARG 202.A NE GLU 206.A OE2 no hydrogen 2.607 N/A ARG 202.A NH2 GLU 206.A OE2 no hydrogen 3.094 N/A ASP 203.A N PRO 199.A O no hydrogen 3.241 N/A ILE 204.A N GLN 200.A O no hydrogen 2.922 N/A LEU 205.A N LEU 201.A O no hydrogen 3.090 N/A GLU 206.A N ARG 202.A O no hydrogen 2.997 N/A THR 207.A N ASP 203.A O no hydrogen 3.134 N/A THR 207.A OG1 ASP 203.A O no hydrogen 3.387 N/A ARG 208.A N ILE 204.A O no hydrogen 2.941 N/A ALA 209.A N GLU 206.A O no hydrogen 3.103 N/A GLU 210.A N GLU 206.A O no hydrogen 3.398 N/A GLU 210.A N THR 207.A O no hydrogen 3.092 N/A ALA 212.A N ARG 208.A O no hydrogen 3.137 N/A PHE 213.A N ALA 209.A O no hydrogen 3.031 N/A ASN 214.A N ILE 5.A O no hydrogen 3.478 N/A GLY 216.A N ASN 214.A O no hydrogen 2.972 N/A VAL 217.A N ASN 214.A O no hydrogen 3.418 N/A ASP 219.A N VAL 259.A O no hydrogen 3.070 N/A LEU 225.A N ASP 221.A O no hydrogen 3.041 N/A CYS 226.A N VAL 222.A O no hydrogen 3.032 N/A CYS 226.A SG VAL 222.A O no hydrogen 3.597 N/A ALA 227.A N VAL 223.A O no hydrogen 2.917 N/A ALA 228.A N PRO 224.A O no hydrogen 2.923 N/A LEU 229.A N LEU 225.A O no hydrogen 2.935 N/A ALA 230.A N CYS 226.A O no hydrogen 2.909 N/A ALA 231.A N ALA 227.A O no hydrogen 2.618 N/A ALA 231.A N ALA 228.A O no hydrogen 3.276 N/A ARG 232.A N LEU 229.A O no hydrogen 3.387 N/A HIS 234.A NE2 THR 53.A O no hydrogen 2.982 N/A ALA 237.A N GLY 54.A O no hydrogen 3.151 N/A ARG 238.A NH1 ASP 236.A OD1 no hydrogen 2.730 N/A ARG 239.A N ASP 236.A OD2 no hydrogen 3.343 N/A ALA 240.A N ASP 236.A O no hydrogen 3.129 N/A LEU 241.A N ALA 237.A O no hydrogen 2.527 N/A ASP 242.A N ARG 238.A O no hydrogen 2.338 N/A LEU 243.A N ARG 239.A O no hydrogen 2.663 N/A LEU 244.A N ALA 240.A O no hydrogen 3.030 N/A ARG 245.A N LEU 241.A O no hydrogen 2.842 N/A ARG 245.A N ASP 242.A O no hydrogen 3.189 N/A ARG 245.A NE GLU 249.A OE1 no hydrogen 3.021 N/A ARG 245.A NH1 GLU 249.A OE2 no hydrogen 3.257 N/A VAL 246.A N ASP 242.A O no hydrogen 2.842 N/A ALA 247.A N LEU 243.A O no hydrogen 2.752 N/A GLU 249.A N ARG 245.A O no hydrogen 2.898 N/A ILE 250.A N VAL 246.A O no hydrogen 2.903 N/A ILE 250.A N ALA 247.A O no hydrogen 3.177 N/A ALA 251.A N ALA 247.A O no hydrogen 3.115 N/A GLU 252.A N GLY 248.A O no hydrogen 3.171 N/A ARG 253.A NH1 GLU 270.A OE2 no hydrogen 3.240 N/A ARG 254.A N ILE 250.A O no hydrogen 3.157 N/A ARG 255.A N GLU 252.A O no hydrogen 3.371 N/A VAL 259.A N VAL 217.A O no hydrogen 2.953 N/A HIS 263.A N ARG 260.A O no hydrogen 3.035 N/A VAL 264.A N ARG 261.A O no hydrogen 3.070 N/A TYR 265.A N ARG 261.A O no hydrogen 3.495 N/A SER 266.A N GLU 262.A O no hydrogen 2.971 N/A ARG 268.A N VAL 264.A O no hydrogen 2.736 N/A ALA 269.A N TYR 265.A O no hydrogen 2.915 N/A GLU 270.A N SER 266.A O no hydrogen 2.991 N/A ILE 271.A N ALA 267.A O no hydrogen 2.982 N/A GLU 272.A N ARG 268.A O no hydrogen 3.333 N/A ARG 273.A N ALA 269.A O no hydrogen 3.349 N/A ASP 274.A N GLU 270.A O no hydrogen 3.102 N/A ARG 275.A N ILE 271.A O no hydrogen 2.910 N/A VAL 276.A N GLU 272.A O no hydrogen 2.686 N/A SER 277.A N ARG 273.A O no hydrogen 3.041 N/A GLU 278.A N ASP 274.A O no hydrogen 2.817 N/A VAL 279.A N ARG 275.A O no hydrogen 3.077 N/A VAL 280.A N VAL 276.A O no hydrogen 3.044 N/A ARG 281.A N SER 277.A O no hydrogen 3.051 N/A ARG 281.A NE GLU 374.A OE1 no hydrogen 2.189 N/A ARG 281.A NH2 GLU 374.A OE2 no hydrogen 2.850 N/A THR 282.A N GLU 278.A O no hydrogen 3.226 N/A THR 282.A OG1 GLU 278.A O no hydrogen 2.852 N/A THR 282.A OG1 VAL 279.A O no hydrogen 2.953 N/A LEU 283.A N ARG 281.A O no hydrogen 2.732 N/A HIS 286.A ND1 TYR 313.A OH no hydrogen 2.894 N/A LYS 288.A N PRO 284.A O no hydrogen 2.787 N/A LYS 288.A NZ VAL 280.A O no hydrogen 2.497 N/A LYS 288.A NZ ARG 281.A O no hydrogen 2.532 N/A LYS 288.A NZ LEU 283.A O no hydrogen 2.782 N/A LEU 289.A N LEU 285.A O no hydrogen 2.964 N/A VAL 290.A N HIS 286.A O no hydrogen 3.075 N/A LEU 291.A N ALA 287.A O no hydrogen 3.132 N/A LEU 292.A N LYS 288.A O no hydrogen 2.986 N/A SER 293.A N LEU 289.A O no hydrogen 2.994 N/A SER 293.A OG LEU 289.A O no hydrogen 2.560 N/A SER 293.A OG VAL 290.A O no hydrogen 3.251 N/A ILE 294.A N VAL 290.A O no hydrogen 2.900 N/A MET 295.A N LEU 291.A O no hydrogen 2.909 N/A MET 296.A N LEU 292.A O no hydrogen 2.824 N/A MET 296.A N SER 293.A O no hydrogen 3.195 N/A LEU 297.A N SER 293.A O no hydrogen 3.205 N/A LEU 297.A N ILE 294.A O no hydrogen 2.920 N/A GLU 298.A N ILE 294.A O no hydrogen 2.933 N/A ALA 304.A N VAL 359.A O no hydrogen 3.061 N/A SER 305.A N GLU 308.A OE1 no hydrogen 3.195 N/A THR 306.A N ARG 357.A O no hydrogen 3.027 N/A GLU 308.A N SER 305.A OG no hydrogen 2.898 N/A ILE 309.A N SER 305.A O no hydrogen 2.944 N/A TYR 310.A N THR 306.A O no hydrogen 3.347 N/A TYR 310.A OH VAL 325.A O no hydrogen 3.080 N/A ARG 312.A N GLU 308.A O no hydrogen 3.384 N/A TYR 313.A N ILE 309.A O no hydrogen 2.891 N/A TYR 313.A OH HIS 286.A ND1 no hydrogen 2.894 N/A LYS 314.A N TYR 310.A O no hydrogen 2.513 N/A GLU 315.A N GLU 311.A O no hydrogen 2.785 N/A LEU 316.A N ARG 312.A O no hydrogen 2.782 N/A THR 317.A N TYR 313.A O no hydrogen 3.023 N/A THR 317.A OG1 TYR 313.A O no hydrogen 3.554 N/A THR 317.A OG1 LYS 314.A O no hydrogen 2.547 N/A SER 318.A N LYS 314.A O no hydrogen 3.231 N/A SER 318.A OG GLU 315.A O no hydrogen 3.428 N/A THR 319.A N GLU 315.A O no hydrogen 2.843 N/A THR 319.A OG1 GLU 315.A O no hydrogen 2.670 N/A LEU 320.A N THR 317.A O no hydrogen 2.707 N/A GLY 321.A N SER 318.A O no hydrogen 2.525 N/A LEU 322.A N THR 317.A O no hydrogen 3.085 N/A VAL 325.A N TYR 313.A OH no hydrogen 3.107 N/A ARG 328.A NH1 ARG 328.A O no hydrogen 3.280 N/A ARG 329.A NH1 GLU 336.A OE2 no hydrogen 3.179 N/A VAL 330.A N THR 326.A O no hydrogen 3.067 N/A SER 331.A N LEU 327.A O no hydrogen 2.534 N/A GLY 332.A N ARG 328.A O no hydrogen 2.895 N/A ILE 333.A N ARG 329.A O no hydrogen 2.557 N/A ILE 334.A N VAL 330.A O no hydrogen 2.787 N/A SER 335.A N SER 331.A O no hydrogen 3.164 N/A SER 335.A OG SER 331.A O no hydrogen 3.171 N/A GLU 336.A N GLY 332.A O no hydrogen 2.987 N/A LEU 337.A N ILE 333.A O no hydrogen 2.888 N/A ASP 338.A N ILE 334.A O no hydrogen 2.866 N/A MET 339.A N SER 335.A O no hydrogen 2.993 N/A MET 339.A N GLU 336.A O no hydrogen 2.590 N/A LEU 340.A N GLU 336.A O no hydrogen 3.003 N/A GLY 341.A N ASP 338.A O no hydrogen 3.186 N/A ILE 342.A N LEU 337.A O no hydrogen 3.147 N/A VAL 343.A N LEU 337.A O no hydrogen 3.283 N/A LYS 344.A N SER 360.A O no hydrogen 2.823 N/A LYS 344.A NZ ASP 338.A O no hydrogen 2.476 N/A LYS 344.A NZ ASP 338.A OD1 no hydrogen 3.258 N/A LYS 344.A NZ ASP 338.A OD2 no hydrogen 3.440 N/A SER 345.A N ASP 338.A OD2 no hydrogen 2.958 N/A SER 345.A OG ASP 338.A OD2 no hydrogen 3.016 N/A ARG 346.A N GLU 358.A O no hydrogen 2.803 N/A VAL 348.A N THR 356.A O no hydrogen 3.465 N/A ARG 350.A N GLY 354.A O no hydrogen 2.983 N/A GLY 351.A N SER 349.A OG no hydrogen 2.804 N/A TYR 353.A N ARG 350.A O no hydrogen 2.953 N/A ARG 357.A N THR 306.A OG1 no hydrogen 3.009 N/A ARG 357.A NH1 SER 331.A O no hydrogen 3.320 N/A ARG 357.A NH1 SER 335.A OG no hydrogen 2.785 N/A ARG 357.A NH2 SER 335.A OG no hydrogen 2.849 N/A GLU 358.A N ARG 346.A O no hydrogen 3.040 N/A VAL 359.A N ALA 304.A O no hydrogen 2.624 N/A SER 360.A N LYS 344.A O no hydrogen 2.984 N/A ASP 362.A N ILE 342.A O no hydrogen 3.467 N/A ALA 367.A N ASP 364.A OD1 no hydrogen 3.264 N/A VAL 368.A N ASP 364.A O no hydrogen 3.164 N/A GLU 369.A N ARG 365.A O no hydrogen 2.868 N/A ASN 370.A N LEU 366.A O no hydrogen 3.161 N/A ALA 371.A N ALA 367.A O no hydrogen 3.223 N/A LEU 372.A N VAL 368.A O no hydrogen 2.760 N/A SER 373.A N GLU 369.A O no hydrogen 2.904 N/A SER 373.A OG GLU 369.A O no hydrogen 3.349 N/A SER 373.A OG ASN 370.A O no hydrogen 2.570 N/A SER 373.A OG ASN 370.A OD1 no hydrogen 3.079 N/A GLU 374.A N ASN 370.A O no hydrogen 3.276 N/A GLU 374.A N ALA 371.A O no hydrogen 2.919 N/A ASP 375.A N LEU 372.A O no hydrogen 3.121 N/A PHE 377.A N ASP 375.A OD1 no hydrogen 2.790 N/A ALA 379.A N ASP 375.A O no hydrogen 3.225 N/A ARG 380.A N PHE 377.A O no hydrogen 3.026 N/A LEU 381.A N VAL 378.A O no hydrogen 2.772 N/A LEU 382.A N ALA 379.A O no hydrogen 2.529 N/A