Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2v5r_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 14.A N HIS 97.A O no hydrogen 3.027 N/A PHE 16.A N ARG 99.A O no hydrogen 3.165 N/A SER 17.A OG ASN 18.A O no hydrogen 3.125 N/A THR 20.A OG1 GLY 21.A O no hydrogen 3.536 N/A GLY 21.A N SER 17.A O no hydrogen 2.334 N/A ALA 22.A N PHE 63.A O no hydrogen 3.191 N/A ILE 24.A N LEU 61.A O no hydrogen 3.106 N/A LYS 27.A N LYS 8.A O no hydrogen 3.400 N/A LYS 27.A NZ ASP 58.A O no hydrogen 3.518 N/A LYS 27.A NZ GLY 59.A O no hydrogen 3.353 N/A SER 29.A N VAL 5.A O no hydrogen 3.009 N/A SER 29.A OG VAL 5.A O no hydrogen 2.713 N/A GLU 35.A N ARG 85.A O no hydrogen 2.958 N/A ILE 37.A N LEU 83.A O no hydrogen 2.810 N/A ILE 39.A N ALA 81.A O no hydrogen 2.858 N/A ARG 40.A N THR 44.A O no hydrogen 2.695 N/A SER 41.A N VAL 79.A O no hydrogen 3.328 N/A THR 44.A N ASP 42.A O no hydrogen 2.856 N/A THR 44.A OG1 ASP 42.A O no hydrogen 3.443 N/A THR 44.A OG1 ASP 42.A OD2 no hydrogen 2.766 N/A VAL 46.A N TRP 38.A O no hydrogen 2.886 N/A VAL 49.A N ARG 53.A O no hydrogen 2.707 N/A LEU 52.A N VAL 49.A O no hydrogen 3.045 N/A GLN 54.A NE2 VAL 49.A O no hydrogen 3.320 N/A ILE 55.A N ASP 48.A OD1 no hydrogen 2.766 N/A GLY 59.A N SER 57.A O no hydrogen 2.443 N/A VAL 62.A N GLN 54.A O no hydrogen 3.212 N/A PHE 63.A N ALA 22.A O no hydrogen 2.732 N/A ASP 70.A N ARG 67.A O no hydrogen 2.659 N/A VAL 75.A N ARG 72.A O no hydrogen 2.910 N/A HIS 76.A N ARG 72.A O no hydrogen 3.010 N/A HIS 76.A NE2 ASP 70.A O no hydrogen 2.906 N/A ALA 77.A N GLN 73.A O no hydrogen 3.040 N/A GLN 78.A NE2 GLN 73.A O no hydrogen 3.079 N/A TYR 80.A N VAL 96.A O no hydrogen 3.023 N/A TYR 80.A OH VAL 75.A O no hydrogen 2.700 N/A ALA 81.A N ILE 39.A O no hydrogen 2.691 N/A CYS 82.A N SER 93.A OG no hydrogen 2.952 N/A CYS 82.A SG LEU 83.A O no hydrogen 3.927 N/A LEU 83.A N ILE 37.A O no hydrogen 2.446 N/A ALA 84.A N ILE 91.A O no hydrogen 2.767 N/A ASN 86.A N GLY 89.A O no hydrogen 2.929 N/A SER 90.A N ASP 347.A OD1 no hydrogen 3.252 N/A ILE 91.A N ALA 84.A O no hydrogen 2.736 N/A SER 93.A N CYS 82.A O no hydrogen 2.902 N/A ARG 94.A NH1 SER 381.A O no hydrogen 3.456 N/A VAL 96.A N TYR 80.A O no hydrogen 3.261 N/A HIS 97.A N ASN 12.A O no hydrogen 3.113 N/A VAL 98.A N GLN 78.A O no hydrogen 3.066 N/A ARG 99.A N ILE 14.A O no hydrogen 3.263 N/A ARG 99.A NE ASP 15.A OD1 no hydrogen 2.800 N/A ARG 99.A NH1 ASP 133.A OD2 no hydrogen 2.553 N/A ARG 99.A NH2 ASP 15.A OD1 no hydrogen 2.879 N/A ARG 99.A NH2 ASP 15.A OD2 no hydrogen 2.804 N/A ALA 100.A N HIS 76.A O no hydrogen 2.983 N/A ILE 103.A N ASN 18.A OD1 no hydrogen 3.036 N/A ALA 110.A N THR 199.A O no hydrogen 3.270 N/A VAL 115.A N VAL 204.A O no hydrogen 2.816 N/A ILE 116.A N GLN 240.A OE1 no hydrogen 2.948 N/A ARG 117.A N THR 206.A O no hydrogen 3.072 N/A ARG 117.A NH1 GLU 207.A OE2 no hydrogen 3.132 N/A GLY 118.A N VAL 173.A O no hydrogen 2.881 N/A ASN 119.A N ILE 116.A O no hydrogen 2.894 N/A ASN 119.A ND2 ILE 116.A O no hydrogen 3.246 N/A ASN 119.A ND2 SER 241.A O no hydrogen 3.300 N/A VAL 121.A N ILE 170.A O no hydrogen 2.971 N/A MET 123.A N LEU 168.A O no hydrogen 3.122 N/A VAL 131.A N PRO 128.A O no hydrogen 3.342 N/A ALA 132.A N SER 129.A O no hydrogen 3.171 N/A PHE 134.A N VAL 131.A O no hydrogen 2.576 N/A PHE 136.A N LYS 187.A O no hydrogen 3.346 N/A ASP 138.A N ARG 185.A O no hydrogen 2.839 N/A TRP 140.A NE1 GLY 166.A O no hydrogen 3.252 N/A LEU 141.A N GLN 183.A O no hydrogen 2.996 N/A ASP 142.A N ARG 146.A O no hydrogen 2.913 N/A SER 143.A N SER 181.A O no hydrogen 2.908 N/A ARG 146.A NH1 TYR 148.A OH no hydrogen 3.494 N/A TYR 148.A N TRP 140.A O no hydrogen 3.058 N/A TYR 148.A OH ASP 142.A OD1 no hydrogen 2.946 N/A TYR 148.A OH ASP 142.A OD2 no hydrogen 2.962 N/A LYS 159.A NZ ASP 177.A OD2 no hydrogen 2.907 N/A TYR 160.A OH TYR 182.A OH no hydrogen 2.800 N/A LEU 161.A N HIS 169.A O no hydrogen 3.244 N/A LEU 163.A N GLU 167.A O no hydrogen 2.840 N/A SER 165.A OG GLU 167.A OE1 no hydrogen 2.683 N/A SER 165.A OG GLU 167.A OE2 no hydrogen 2.706 N/A GLY 166.A N LEU 163.A O no hydrogen 2.712 N/A GLU 167.A N GLU 167.A OE1 no hydrogen 2.690 N/A LEU 168.A N MET 123.A O no hydrogen 2.945 N/A HIS 169.A N LEU 161.A O no hydrogen 2.541 N/A ILE 170.A N VAL 121.A O no hydrogen 2.812 N/A ARG 171.A N LYS 159.A O no hydrogen 2.646 N/A ARG 171.A NE GLU 172.A OE1 no hydrogen 3.134 N/A ARG 171.A NE GLU 172.A OE2 no hydrogen 2.312 N/A ARG 171.A NH2 GLU 172.A OE1 no hydrogen 2.492 N/A GLY 178.A N PRO 175.A O no hydrogen 2.961 N/A LYS 180.A NZ ASP 142.A OD1 no hydrogen 3.560 N/A LYS 180.A NZ ASP 142.A OD2 no hydrogen 3.161 N/A LYS 180.A NZ TYR 148.A OH no hydrogen 3.381 N/A LYS 180.A NZ TYR 182.A OH no hydrogen 2.866 N/A TYR 182.A N GLY 201.A O no hydrogen 3.174 N/A TYR 182.A OH TYR 160.A OH no hydrogen 2.800 N/A GLN 183.A N LEU 141.A O no hydrogen 3.057 N/A ARG 185.A N LEU 139.A O no hydrogen 3.424 N/A ARG 185.A NE ASP 138.A OD1 no hydrogen 2.575 N/A ARG 185.A NH1 ASP 138.A OD1 no hydrogen 3.135 N/A ARG 185.A NH1 ASP 138.A OD2 no hydrogen 2.625 N/A THR 186.A OG1 ARG 195.A O no hydrogen 3.475 N/A LYS 187.A N PHE 136.A O no hydrogen 3.071 N/A HIS 188.A N GLU 193.A O no hydrogen 3.159 N/A ARG 189.A N PHE 134.A O no hydrogen 2.901 N/A LEU 190.A N HIS 188.A ND1 no hydrogen 3.215 N/A THR 191.A N HIS 188.A ND1 no hydrogen 3.213 N/A GLU 193.A N THR 191.A OG1 no hydrogen 2.765 N/A ARG 195.A N THR 186.A O no hydrogen 3.456 N/A ARG 195.A NE GLU 193.A OE2 no hydrogen 2.884 N/A SER 197.A OG CYS 184.A O no hydrogen 3.507 N/A SER 197.A OG THR 199.A O no hydrogen 2.777 N/A ALA 198.A N SER 108.A O no hydrogen 2.817 N/A LYS 200.A NZ GLN 183.A OE1 no hydrogen 3.436 N/A ARG 202.A N ASN 112.A OD1 no hydrogen 2.760 N/A VAL 204.A N GLU 113.A O no hydrogen 3.041 N/A THR 206.A N VAL 115.A O no hydrogen 2.735 N/A VAL 212.A N TYR 242.A O no hydrogen 2.595 N/A ASP 220.A N ASN 217.A O no hydrogen 2.553 N/A LYS 221.A N PRO 218.A O no hydrogen 3.209 N/A LYS 221.A NZ GLU 299.A OE2 no hydrogen 2.848 N/A LYS 221.A NZ SER 300.A O no hydrogen 3.379 N/A GLN 223.A N GLU 302.A O no hydrogen 3.162 N/A ILE 225.A N VAL 304.A O no hydrogen 2.970 N/A LEU 229.A N THR 308.A O no hydrogen 2.816 N/A ALA 230.A N ALA 280.A O no hydrogen 3.294 N/A SER 231.A N GLU 228.A O no hydrogen 3.325 N/A SER 231.A OG GLU 228.A O no hydrogen 2.715 N/A SER 232.A OG ASN 152.A O no hydrogen 3.138 N/A TYR 233.A N ILE 277.A O no hydrogen 2.901 N/A TYR 233.A OH ASP 284.A OD2 no hydrogen 3.387 N/A LEU 235.A N LEU 275.A O no hydrogen 2.738 N/A GLN 240.A NE2 TYR 114.A O no hydrogen 3.493 N/A SER 241.A N ASN 119.A OD1 no hydrogen 2.978 N/A SER 241.A OG VAL 212.A O no hydrogen 3.242 N/A SER 241.A OG PRO 243.A O no hydrogen 2.691 N/A SER 246.A N ASN 293.A O no hydrogen 3.200 N/A SER 246.A OG ASN 293.A O no hydrogen 3.421 N/A ARG 248.A N VAL 291.A O no hydrogen 2.654 N/A TRP 249.A NE1 GLY 273.A O no hydrogen 2.818 N/A TYR 250.A N LEU 289.A O no hydrogen 2.902 N/A LYS 251.A N GLN 260.A O no hydrogen 2.632 N/A LYS 251.A NZ GLU 283.A O no hydrogen 2.886 N/A LYS 251.A NZ SER 285.A O no hydrogen 2.959 N/A PHE 252.A N LYS 287.A O no hydrogen 3.002 N/A ILE 253.A N ARG 258.A O no hydrogen 3.426 N/A THR 256.A N ILE 253.A O no hydrogen 3.005 N/A THR 256.A OG1 ILE 253.A O no hydrogen 3.122 N/A GLN 260.A N LYS 251.A O no hydrogen 2.600 N/A VAL 262.A N TRP 249.A O no hydrogen 2.755 N/A ASN 265.A N VAL 268.A O no hydrogen 2.733 N/A ARG 267.A N ASN 265.A OD1 no hydrogen 2.894 N/A ARG 267.A NH1 LYS 278.A O no hydrogen 2.860 N/A ARG 267.A NH1 ASP 284.A OD2 no hydrogen 3.100 N/A ARG 267.A NH2 ASP 284.A OD1 no hydrogen 2.690 N/A ARG 267.A NH2 ASP 284.A OD2 no hydrogen 2.771 N/A VAL 268.A N ASN 265.A OD1 no hydrogen 2.471 N/A LYS 269.A N ILE 276.A O no hydrogen 2.960 N/A LYS 269.A NZ ASN 265.A O no hydrogen 2.658 N/A GLN 270.A NE2 PHE 247.A O no hydrogen 3.632 N/A VAL 271.A N THR 274.A O no hydrogen 2.937 N/A THR 274.A N VAL 271.A O no hydrogen 2.788 N/A THR 274.A OG1 HIS 169.A NE2 no hydrogen 3.075 N/A LEU 275.A N LEU 235.A O no hydrogen 2.819 N/A ILE 276.A N LYS 269.A O no hydrogen 2.722 N/A ILE 277.A N TYR 233.A O no hydrogen 2.872 N/A LYS 278.A N ARG 267.A O no hydrogen 3.439 N/A ALA 280.A N SER 231.A O no hydrogen 2.955 N/A ASP 284.A N VAL 281.A O no hydrogen 3.204 N/A SER 285.A N VAL 282.A O no hydrogen 3.342 N/A SER 285.A OG VAL 282.A O no hydrogen 3.521 N/A SER 285.A OG VAL 307.A O no hydrogen 3.557 N/A GLY 286.A N LEU 305.A O no hydrogen 2.719 N/A LYS 287.A NZ GLU 302.A OE2 no hydrogen 3.101 N/A TYR 288.A N THR 303.A O no hydrogen 2.858 N/A TYR 288.A OH ASP 284.A O no hydrogen 2.541 N/A LEU 289.A N TYR 250.A O no hydrogen 2.852 N/A CYS 290.A N VAL 301.A O no hydrogen 3.132 N/A VAL 291.A N ARG 248.A O no hydrogen 2.850 N/A VAL 292.A N GLU 299.A O no hydrogen 2.941 N/A ASN 293.A N SER 246.A O no hydrogen 3.123 N/A ASN 294.A N GLY 297.A O no hydrogen 2.841 N/A ASN 294.A ND2 VAL 212.A O no hydrogen 3.233 N/A ASN 294.A ND2 PRO 243.A O no hydrogen 3.068 N/A VAL 296.A N ASN 294.A OD1 no hydrogen 3.301 N/A GLY 297.A N ASN 294.A O no hydrogen 2.952 N/A GLY 297.A N ASN 294.A OD1 no hydrogen 3.173 N/A SER 300.A N GLU 299.A OE2 no hydrogen 2.718 N/A VAL 301.A N CYS 290.A O no hydrogen 2.917 N/A THR 303.A N TYR 288.A O no hydrogen 2.966 N/A THR 303.A OG1 VAL 301.A O no hydrogen 3.314 N/A VAL 304.A N GLN 223.A O no hydrogen 2.909 N/A LEU 305.A N GLY 286.A O no hydrogen 2.647 N/A THR 306.A N ILE 225.A O no hydrogen 2.976 N/A THR 306.A OG1 ILE 225.A O no hydrogen 3.308 N/A THR 306.A OG1 ASP 226.A OD1 no hydrogen 2.947 N/A VAL 307.A N SER 285.A OG no hydrogen 2.880 N/A THR 308.A N VAL 227.A O no hydrogen 2.658 N/A THR 308.A OG1 VAL 227.A O no hydrogen 3.289 N/A ALA 309.A N ASN 337.A O no hydrogen 2.664 N/A GLN 320.A N GLU 387.A O no hydrogen 3.055 N/A THR 321.A OG1 LEU 390.A O no hydrogen 3.044 N/A VAL 322.A N LYS 389.A O no hydrogen 3.296 N/A CYS 332.A SG SER 356.A O no hydrogen 3.985 N/A ASN 337.A ND2 VAL 307.A O no hydrogen 2.929 N/A LYS 340.A NZ ASP 378.A OD2 no hydrogen 3.317 N/A THR 341.A OG1 LYS 340.A O no hydrogen 2.623 N/A SER 343.A OG PHE 374.A O no hydrogen 3.351 N/A TRP 344.A NE1 GLU 355.A O no hydrogen 2.563 N/A LYS 346.A N LYS 349.A O no hydrogen 2.888 N/A LYS 346.A NZ GLU 366.A O no hydrogen 3.276 N/A LYS 346.A NZ LYS 368.A O no hydrogen 3.134 N/A ASP 347.A N MET 370.A O no hydrogen 3.036 N/A LYS 349.A N LYS 346.A O no hydrogen 3.291 N/A HIS 353.A NE2 VAL 357.A O no hydrogen 3.151 N/A LEU 358.A N PHE 330.A O no hydrogen 3.161 N/A LYS 368.A NZ LYS 365.A O no hydrogen 3.490 N/A MET 370.A N ASP 347.A OD1 no hydrogen 2.817 N/A TYR 371.A N ALA 386.A O no hydrogen 2.423 N/A GLN 372.A N MET 345.A O no hydrogen 3.101 N/A GLN 372.A NE2 ILE 92.A O no hydrogen 3.476 N/A GLN 372.A NE2 GLU 383.A OE1 no hydrogen 3.129 N/A CYS 373.A SG SER 343.A O no hydrogen 3.677 N/A PHE 374.A N SER 343.A O no hydrogen 2.837 N/A VAL 375.A N ALA 382.A O no hydrogen 2.967 N/A ARG 376.A N PHE 374.A O no hydrogen 2.915 N/A ALA 382.A N VAL 375.A O no hydrogen 3.341 N/A ALA 384.A N CYS 373.A O no hydrogen 3.010 N/A GLU 387.A N PRO 318.A O no hydrogen 2.856 N/A LEU 388.A N GLY 369.A O no hydrogen 2.532 N/A