Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2vyq_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 5.A N PRO 127.A O no hydrogen 2.856 N/A TYR 7.A N GLY 126.A O no hydrogen 3.103 N/A TYR 7.A OH ASN 43.A OD1 no hydrogen 2.955 N/A ALA 11.A N ARG 8.A O no hydrogen 2.961 N/A PHE 13.A N ILE 124.A O no hydrogen 2.885 N/A GLY 15.A N VAL 122.A O no hydrogen 2.919 N/A VAL 17.A N SER 120.A O no hydrogen 2.915 N/A ILE 18.A N LYS 36.A O no hydrogen 2.792 N/A SER 19.A N LYS 36.A O no hydrogen 3.439 N/A GLU 21.A N HIS 34.A O no hydrogen 2.968 N/A LEU 23.A N VAL 32.A O no hydrogen 2.862 N/A LYS 25.A N PRO 189.A O no hydrogen 3.046 N/A GLY 28.A N LYS 25.A O no hydrogen 3.078 N/A ILE 29.A N ASN 190.A OD1 no hydrogen 2.810 N/A GLN 33.A N VAL 91.A O no hydrogen 2.868 N/A HIS 34.A N GLU 21.A O no hydrogen 2.820 N/A HIS 34.A ND1 TYR 193.A OH no hydrogen 2.695 N/A HIS 34.A NE2 ASP 80.A OD2 no hydrogen 2.719 N/A ILE 35.A N LEU 89.A O no hydrogen 2.990 N/A LYS 36.A N SER 19.A O no hydrogen 2.943 N/A LYS 36.A NZ ASP 81.A OD1 no hydrogen 3.293 N/A LYS 36.A NZ ASP 81.A OD2 no hydrogen 2.779 N/A PHE 37.A N ILE 87.A O no hydrogen 2.781 N/A ASP 38.A N LYS 16.A O no hydrogen 2.711 N/A LEU 39.A N LYS 85.A O no hydrogen 2.860 N/A THR 40.A N ASP 38.A OD1 no hydrogen 3.075 N/A THR 40.A OG1 ASP 38.A OD1 no hydrogen 2.738 N/A THR 40.A OG1 ASP 38.A OD2 no hydrogen 3.287 N/A GLY 42.A N LEU 39.A O no hydrogen 3.327 N/A ASN 43.A N TYR 7.A OH no hydrogen 3.022 N/A TYR 46.A OH SER 75.A OG no hydrogen 2.806 N/A TYR 46.A OH THR 76.A O no hydrogen 2.858 N/A TYR 46.A OH THR 86.A O no hydrogen 2.735 N/A ILE 47.A N GLN 50.A OE1 no hydrogen 2.903 N/A GLN 50.A N ILE 47.A O no hydrogen 3.353 N/A GLN 50.A NE2 PRO 3.A O no hydrogen 2.795 N/A GLN 50.A NE2 GLY 129.A O no hydrogen 3.171 N/A SER 51.A N VAL 128.A O no hydrogen 2.890 N/A ILE 52.A N TYR 71.A O no hydrogen 2.969 N/A GLY 53.A N THR 125.A O no hydrogen 2.908 N/A ILE 54.A N ARG 69.A O no hydrogen 2.943 N/A ILE 55.A N LYS 123.A O no hydrogen 3.135 N/A ASP 60.A N LYS 64.A O no hydrogen 2.867 N/A ASN 62.A N ASP 60.A OD1 no hydrogen 2.968 N/A GLY 63.A N ASP 60.A O no hydrogen 3.103 N/A LYS 64.A N ASP 60.A OD1 no hydrogen 3.044 N/A GLU 66.A N GLY 58.A O no hydrogen 3.237 N/A ARG 69.A N ILE 54.A O no hydrogen 3.015 N/A ARG 69.A NH1 GLU 66.A OE1 no hydrogen 2.924 N/A ARG 69.A NH1 LYS 67.A O no hydrogen 2.821 N/A ARG 69.A NH2 GLU 66.A OE1 no hydrogen 3.094 N/A TYR 71.A N ILE 52.A O no hydrogen 2.847 N/A SER 72.A OG GLU 293.A OE2.A no hydrogen 3.008 N/A ILE 73.A N GLN 50.A O no hydrogen 2.925 N/A ALA 74.A N SER 88.A O no hydrogen 2.820 N/A SER 75.A OG TYR 46.A OH no hydrogen 2.806 N/A SER 75.A OG THR 76.A O no hydrogen 3.539 N/A THR 76.A OG1 GLU 166.A OE2 no hydrogen 2.534 N/A ARG 77.A N GLU 48.A OE2 no hydrogen 3.023 N/A ARG 77.A NE GLU 48.A OE1 no hydrogen 3.447 N/A ARG 77.A NE GLU 48.A OE2 no hydrogen 3.166 N/A ARG 77.A NH2 GLU 48.A OE1 no hydrogen 2.970 N/A HIS 78.A N THR 76.A OG1 no hydrogen 3.272 N/A HIS 78.A ND1 ASP 84.A OD1 no hydrogen 2.603 N/A HIS 78.A NE2 ASN 170.A OD1 no hydrogen 2.670 N/A GLY 79.A N THR 76.A O no hydrogen 2.954 N/A VAL 82.A N GLY 79.A O no hydrogen 3.038 N/A ASP 83.A N HIS 78.A O no hydrogen 3.095 N/A ASP 84.A N HIS 78.A O no hydrogen 2.892 N/A LYS 85.A N ASP 83.A OD1 no hydrogen 3.113 N/A ILE 87.A N PHE 37.A O no hydrogen 3.128 N/A SER 88.A N SER 75.A OG no hydrogen 3.085 N/A SER 88.A OG ASP 80.A OD2 no hydrogen 2.691 N/A LEU 89.A N ILE 35.A O no hydrogen 2.848 N/A VAL 91.A N GLN 33.A O no hydrogen 2.942 N/A GLN 93.A N ILE 31.A O no hydrogen 2.975 N/A LEU 94.A N SER 110.A OG no hydrogen 2.958 N/A TYR 96.A N VAL 105.A O no hydrogen 3.181 N/A VAL 105.A N TYR 96.A O no hydrogen 3.224 N/A GLY 107.A N LEU 94.A O no hydrogen 2.980 N/A CYS 109.A SG ILE 54.A O no hydrogen 3.853 N/A THR 111.A N GLY 107.A O no hydrogen 3.192 N/A THR 111.A OG1 GLN 93.A OE1 no hydrogen 3.011 N/A THR 111.A OG1 GLY 107.A O no hydrogen 2.676 N/A TYR 112.A N VAL 108.A O no hydrogen 3.195 N/A LEU 113.A N CYS 109.A O no hydrogen 2.984 N/A THR 114.A N SER 110.A O no hydrogen 2.994 N/A THR 114.A OG1 SER 110.A O no hydrogen 2.749 N/A THR 114.A OG1 THR 111.A O no hydrogen 3.389 N/A THR 114.A OG1 HIS 115.A ND1 no hydrogen 3.190 N/A HIS 115.A N THR 111.A O no hydrogen 3.152 N/A HIS 115.A ND1 THR 111.A O no hydrogen 3.068 N/A HIS 115.A ND1 THR 114.A OG1 no hydrogen 3.190 N/A ILE 116.A N LEU 113.A O no hydrogen 3.107 N/A GLY 119.A N VAL 17.A O no hydrogen 2.883 N/A SER 120.A N GLU 117.A O no hydrogen 3.133 N/A SER 120.A OG GLU 117.A O no hydrogen 2.807 N/A VAL 122.A N GLY 15.A O no hydrogen 2.927 N/A ILE 124.A N PHE 13.A O no hydrogen 2.836 N/A THR 125.A N GLY 53.A O no hydrogen 2.927 N/A GLY 126.A N TYR 7.A O no hydrogen 2.931 N/A VAL 128.A N SER 51.A O no hydrogen 2.846 N/A GLU 131.A N GLU 131.A OE1 no hydrogen 2.910 N/A GLU 139.A N ASP 137.A OD1 no hydrogen 2.949 N/A ALA 140.A N ASP 137.A O no hydrogen 3.289 N/A ASN 141.A N LYS 247.A O no hydrogen 3.334 N/A ASN 141.A ND2 PHE 178.A O no hydrogen 3.613 N/A VAL 142.A N PHE 178.A O no hydrogen 2.905 N/A ILE 143.A N HIS 249.A O no hydrogen 2.925 N/A MET 144.A N TRP 180.A O no hydrogen 2.852 N/A LEU 145.A N TYR 251.A O no hydrogen 2.839 N/A ALA 146.A N VAL 182.A O no hydrogen 2.946 N/A GLY 147.A N CYS 253.A O no hydrogen 3.113 N/A GLY 148.A N GLY 184.A O no hydrogen 3.020 N/A GLY 150.A N GLY 147.A O no hydrogen 2.898 N/A ILE 151.A N GLY 148.A O no hydrogen 3.171 N/A THR 152.A N THR 149.A O no hydrogen 3.088 N/A THR 152.A OG1 THR 149.A O no hydrogen 2.759 N/A ARG 155.A N ILE 151.A O no hydrogen 2.934 N/A ARG 155.A NH1 ALA 74.A O no hydrogen 2.778 N/A ARG 155.A NH1 ASP 80.A OD1 no hydrogen 2.906 N/A ARG 155.A NH2 ASP 80.A OD1 no hydrogen 3.400 N/A THR 156.A N THR 152.A O no hydrogen 3.470 N/A THR 156.A OG1 PRO 153.A O no hydrogen 2.647 N/A TYR 157.A N PRO 153.A O no hydrogen 3.181 N/A TYR 157.A OH MET 132.A O no hydrogen 2.587 N/A LEU 158.A N MET 154.A O no hydrogen 2.945 N/A TRP 159.A N ARG 155.A O no hydrogen 2.935 N/A ARG 160.A N THR 156.A O no hydrogen 3.244 N/A MET 161.A N TYR 157.A O no hydrogen 2.940 N/A PHE 162.A N LEU 158.A O no hydrogen 2.923 N/A PHE 162.A N TRP 159.A O no hydrogen 3.343 N/A LYS 163.A N TRP 159.A O no hydrogen 2.968 N/A LYS 163.A NZ GLU 196.A OE2 no hydrogen 2.836 N/A ARG 167.A N LYS 163.A O no hydrogen 3.062 N/A ARG 167.A NE MET 161.A O no hydrogen 2.932 N/A ARG 167.A NH2 PHE 175.A O no hydrogen 3.045 N/A ALA 168.A N ASP 164.A O no hydrogen 3.110 N/A ALA 169.A N ALA 165.A O no hydrogen 3.119 N/A ASN 170.A ND2 GLU 166.A OE1 no hydrogen 2.858 N/A TYR 173.A N ASN 170.A O no hydrogen 3.015 N/A LYS 176.A N PRO 138.A O no hydrogen 2.906 N/A SER 179.A N ASN 207.A O no hydrogen 2.840 N/A SER 179.A OG ASN 207.A O no hydrogen 2.868 N/A TRP 180.A N VAL 142.A O no hydrogen 2.999 N/A TRP 180.A NE1 THR 211.A OG1 no hydrogen 2.964 N/A LEU 181.A N ARG 209.A O no hydrogen 2.956 N/A VAL 182.A N MET 144.A O no hydrogen 2.862 N/A PHE 183.A N THR 211.A O no hydrogen 2.910 N/A GLY 184.A N ALA 146.A O no hydrogen 2.901 N/A VAL 185.A N ALA 213.A O no hydrogen 3.098 N/A THR 187.A OG1 ASN 190.A OD1 no hydrogen 2.686 N/A THR 188.A N GLU 217.A OE2 no hydrogen 2.797 N/A THR 188.A OG1 GLU 217.A OE1 no hydrogen 2.710 N/A THR 188.A OG1 GLU 217.A OE2 no hydrogen 3.427 N/A ASN 190.A N THR 187.A O no hydrogen 3.010 N/A ASN 190.A N THR 187.A OG1 no hydrogen 3.175 N/A ASN 190.A ND2 ILE 29.A O no hydrogen 2.872 N/A ILE 191.A N THR 188.A O no hydrogen 2.983 N/A TYR 193.A OH HIS 34.A ND1 no hydrogen 2.695 N/A LYS 194.A N ILE 191.A O no hydrogen 3.283 N/A GLU 195.A N GLU 195.A OE1 no hydrogen 2.930 N/A LEU 197.A N TYR 193.A O no hydrogen 2.993 N/A GLU 198.A N LYS 194.A O no hydrogen 3.002 N/A GLU 199.A N GLU 195.A O no hydrogen 2.974 N/A ILE 200.A N GLU 196.A O no hydrogen 3.049 N/A GLN 201.A N LEU 197.A O no hydrogen 3.134 N/A GLN 201.A NE2 LEU 210.A O no hydrogen 3.685 N/A GLN 202.A N GLU 198.A O no hydrogen 3.100 N/A LYS 203.A N GLU 199.A O no hydrogen 3.148 N/A TYR 204.A N ILE 200.A O no hydrogen 2.871 N/A ASN 207.A N TYR 204.A O no hydrogen 3.176 N/A ASN 207.A ND2 GLY 177.A O no hydrogen 2.788 N/A PHE 208.A N TYR 204.A O no hydrogen 2.985 N/A ARG 209.A N SER 179.A O no hydrogen 2.929 N/A THR 211.A N LEU 181.A O no hydrogen 2.876 N/A TYR 212.A OH GLU 198.A OE2 no hydrogen 2.729 N/A ALA 213.A N PHE 183.A O no hydrogen 2.946 N/A ILE 214.A N GLN 218.A OE1 no hydrogen 2.937 N/A SER 215.A N VAL 185.A O no hydrogen 3.217 N/A ARG 216.A N PRO 186.A O no hydrogen 2.924 N/A GLU 217.A N ILE 214.A O no hydrogen 3.214 N/A ASN 220.A N GLY 224.A O no hydrogen 2.913 N/A ASN 220.A ND2 ASP 230.A OD2 no hydrogen 3.164 N/A GLN 222.A N ASN 220.A OD1 no hydrogen 2.918 N/A GLY 223.A N ASN 220.A O no hydrogen 3.084 N/A GLY 224.A N ASN 220.A OD1 no hydrogen 3.073 N/A MET 226.A N GLN 218.A O no hydrogen 2.996 N/A TYR 227.A N ASP 230.A OD2 no hydrogen 3.009 N/A GLN 229.A N GLN 229.A OE1.B no hydrogen 2.898 N/A GLN 229.A NE2.B MET 258.A O no hydrogen 3.073 N/A ASP 230.A N TYR 227.A O no hydrogen 2.847 N/A ARG 231.A N TYR 227.A O no hydrogen 3.348 N/A ARG 231.A NE TYR 212.A O no hydrogen 2.806 N/A ARG 231.A NH1 GLU 234.A OE1 no hydrogen 2.913 N/A ARG 231.A NH2 TYR 212.A O no hydrogen 3.346 N/A ARG 231.A NH2 GLN 218.A OE1 no hydrogen 3.079 N/A VAL 232.A N ILE 228.A O no hydrogen 3.018 N/A ALA 233.A N GLN 229.A O no hydrogen 3.075 N/A GLU 234.A N ASP 230.A O no hydrogen 2.986 N/A HIS 235.A N ARG 231.A O no hydrogen 3.039 N/A HIS 235.A ND1 ARG 231.A O no hydrogen 2.981 N/A ALA 236.A N ALA 233.A O no hydrogen 3.352 N/A LEU 239.A N HIS 235.A O no hydrogen 2.968 N/A TRP 240.A N ALA 236.A O no hydrogen 2.932 N/A TRP 240.A NE1 GLU 273.A OE1 no hydrogen 3.123 N/A GLN 241.A N ASP 237.A O no hydrogen 2.999 N/A LEU 242.A N GLU 238.A O no hydrogen 3.077 N/A ILE 243.A N LEU 239.A O no hydrogen 2.931 N/A LYS 244.A N TRP 240.A O no hydrogen 3.138 N/A LYS 244.A NZ GLU 273.A OE1 no hydrogen 2.756 N/A LYS 244.A NZ GLU 273.A OE2 no hydrogen 3.284 N/A ASN 245.A N LEU 242.A O no hydrogen 3.142 N/A LYS 247.A N ASN 245.A OD1 no hydrogen 3.020 N/A LYS 247.A NZ ASP 137.A OD2 no hydrogen 2.741 N/A THR 248.A N ASN 245.A O no hydrogen 3.098 N/A THR 248.A OG1 ASN 141.A OD1 no hydrogen 3.259 N/A THR 248.A OG1 LEU 242.A O no hydrogen 2.658 N/A HIS 249.A N ASN 141.A O no hydrogen 2.895 N/A THR 250.A N ARG 289.A O no hydrogen 3.016 N/A TYR 251.A N ILE 143.A O no hydrogen 2.793 N/A TYR 251.A OH LEU 133.A O no hydrogen 2.633 N/A ILE 252.A N HIS 291.A O no hydrogen 2.848 N/A CYS 253.A N LEU 145.A O no hydrogen 3.085 N/A CYS 253.A SG GLU 293.A O no hydrogen 3.349 N/A CYS 253.A SG GLU 293.A OE1.B no hydrogen 3.573 N/A ARG 256.A N SER 295.A OXT no hydrogen 3.148 N/A ARG 256.A NE THR 294.A O no hydrogen 3.543 N/A ARG 256.A NE THR 294.A OG1 no hydrogen 3.027 N/A ARG 256.A NH2 THR 294.A O no hydrogen 3.318 N/A GLY 257.A N GLU 259.A OE2 no hydrogen 3.176 N/A MET 258.A N PRO 255.A O no hydrogen 3.240 N/A GLU 259.A N GLU 259.A OE2 no hydrogen 3.120 N/A ASP 263.A N GLU 259.A O no hydrogen 2.922 N/A ALA 264.A N GLU 260.A O no hydrogen 3.087 N/A ALA 265.A N GLY 261.A O no hydrogen 3.198 N/A LEU 266.A N ILE 262.A O no hydrogen 3.095 N/A SER 267.A N ASP 263.A O no hydrogen 2.874 N/A ALA 268.A N ALA 264.A O no hydrogen 3.227 N/A ALA 269.A N ALA 265.A O no hydrogen 3.260 N/A ALA 270.A N LEU 266.A O no hydrogen 2.945 N/A ALA 271.A N SER 267.A O no hydrogen 3.011 N/A LYS 272.A N ALA 269.A O no hydrogen 3.311 N/A LYS 272.A NZ ASP 237.A OD1 no hydrogen 3.566 N/A LYS 272.A NZ ASP 237.A OD2 no hydrogen 3.565 N/A GLU 273.A N ALA 270.A O no hydrogen 3.032 N/A GLY 274.A N ALA 271.A O no hydrogen 3.132 N/A VAL 275.A N ALA 270.A O no hydrogen 3.106 N/A TRP 277.A NE1 ASP 263.A OD1 no hydrogen 3.114 N/A TYR 280.A N THR 276.A O no hydrogen 3.084 N/A GLN 281.A N TRP 277.A O no hydrogen 2.730 N/A LYS 282.A N SER 278.A O no hydrogen 3.189 N/A ASP 283.A N ASP 279.A O no hydrogen 3.244 N/A LEU 284.A N TYR 280.A O no hydrogen 3.013 N/A LYS 285.A N GLN 281.A O no hydrogen 2.882 N/A LYS 286.A N LYS 282.A O no hydrogen 3.078 N/A ALA 287.A N ASP 283.A O no hydrogen 2.996 N/A GLY 288.A N LYS 285.A O no hydrogen 3.209 N/A ARG 289.A N LEU 284.A O no hydrogen 2.947 N/A ARG 289.A NH1 THR 248.A O no hydrogen 3.048 N/A HIS 291.A N THR 250.A O no hydrogen 2.858 N/A HIS 291.A ND1 THR 250.A O no hydrogen 3.049 N/A GLU 293.A N ILE 252.A O no hydrogen 2.915 N/A THR 294.A OG1 GLU 259.A OE1 no hydrogen 2.945 N/A SER 295.A N GLY 254.A O no hydrogen 3.414 N/A