Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2w0x_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLY 5.A N THR 32.A O no hydrogen 3.047 N/A SER 6.A OG GLU 255.A OE2 no hydrogen 2.711 N/A GLY 7.A N SER 4.A O no hydrogen 3.040 N/A ARG 10.A NH1 VAL 257.A O no hydrogen 3.252 N/A ARG 10.A NH2 VAL 257.A O no hydrogen 2.898 N/A GLU 12.A N GLY 17.A O no hydrogen 3.087 N/A ALA 19.A N ARG 10.A O no hydrogen 2.773 N/A ASP 21.A N GLN 24.A OE1 no hydrogen 2.932 N/A SER 23.A N ASP 21.A OD1 no hydrogen 2.635 N/A SER 23.A OG ASP 21.A OD1 no hydrogen 3.123 N/A SER 23.A OG ASP 21.A OD2 no hydrogen 3.476 N/A GLN 24.A N ASP 21.A O no hydrogen 2.913 N/A GLN 24.A NE2 LEU 278.A O no hydrogen 2.949 N/A LEU 25.A N GLU 22.A O no hydrogen 2.988 N/A ARG 26.A N GLU 275.A OE2 no hydrogen 3.316 N/A ARG 26.A NH2 GLY 186.A O no hydrogen 2.813 N/A TYR 28.A OH HIS 273.A NE2 no hydrogen 3.288 N/A TYR 28.A OH GLU 275.A OE1 no hydrogen 2.832 N/A SER 29.A OG TYR 242.A OH no hydrogen 3.213 N/A THR 32.A OG1 GLU 255.A OE1 no hydrogen 2.739 N/A ARG 33.A N GLY 253.A O no hydrogen 2.984 N/A ILE 35.A N GLU 255.A O no hydrogen 2.876 N/A ARG 37.A NH1 ASP 262.A OD1 no hydrogen 3.275 N/A ARG 37.A NH1 ASP 262.A OD2 no hydrogen 3.045 N/A LEU 38.A N VAL 56.A O no hydrogen 2.824 N/A SER 39.A OG SER 41.A OG no hydrogen 2.859 N/A SER 39.A OG ASP 59.A OD1 no hydrogen 3.503 N/A SER 39.A OG ASP 59.A OD2 no hydrogen 2.707 N/A GLN 40.A N ASP 59.A OD1 no hydrogen 2.914 N/A SER 41.A N SER 39.A OG no hydrogen 3.189 N/A SER 41.A OG SER 39.A OG no hydrogen 2.859 N/A ASP 42.A N SER 39.A O no hydrogen 2.734 N/A ARG 44.A N ASP 42.A OD1 no hydrogen 3.012 N/A ARG 44.A NE ASP 42.A OD1 no hydrogen 3.302 N/A ARG 44.A NE ASP 42.A OD2 no hydrogen 3.171 N/A ARG 44.A NH2 ASP 42.A OD2 no hydrogen 2.959 N/A ALA 45.A N ASP 42.A O no hydrogen 2.841 N/A GLU 47.A N PRO 43.A O no hydrogen 3.064 N/A LEU 48.A N ARG 44.A O no hydrogen 3.015 N/A ILE 49.A N ALA 45.A O no hydrogen 3.054 N/A GLU 50.A N GLU 46.A O no hydrogen 3.006 N/A ASN 51.A N GLU 47.A O no hydrogen 2.996 N/A ASN 51.A ND2 GLU 47.A O no hydrogen 3.027 N/A GLU 52.A N ILE 49.A O no hydrogen 2.891 N/A GLU 53.A N LEU 48.A O no hydrogen 2.727 N/A VAL 56.A N PRO 36.A O no hydrogen 2.876 N/A LEU 57.A N VAL 263.A O no hydrogen 2.768 N/A THR 58.A N LEU 38.A O no hydrogen 2.967 N/A THR 58.A OG1 LEU 38.A O no hydrogen 3.171 N/A LEU 62.A N THR 60.A OG1 no hydrogen 3.025 N/A TYR 64.A N ASN 61.A O no hydrogen 3.243 N/A ALA 66.A N VAL 63.A O no hydrogen 2.854 N/A LEU 67.A N TYR 64.A O no hydrogen 3.084 N/A LYS 68.A NZ PRO 65.A O no hydrogen 2.871 N/A TRP 69.A N ALA 66.A O no hydrogen 2.829 N/A TRP 69.A NE1 ASP 154.A OD2 no hydrogen 2.776 N/A TYR 73.A N ASP 70.A OD1 no hydrogen 2.783 N/A TYR 73.A OH ASP 154.A OD2 no hydrogen 2.903 N/A LEU 74.A N ASP 70.A O no hydrogen 3.072 N/A GLN 75.A N LEU 71.A O no hydrogen 2.860 N/A GLU 76.A N GLU 72.A O no hydrogen 3.111 N/A ASN 77.A N LEU 74.A O no hydrogen 2.983 N/A ASN 77.A ND2 TYR 73.A O no hydrogen 2.973 N/A ILE 78.A N LEU 74.A O no hydrogen 2.767 N/A PHE 83.A N MET 116.A O no hydrogen 2.639 N/A SER 84.A N GLN 141.A OE1 no hydrogen 3.006 N/A SER 84.A OG GLU 115.A OE1 no hydrogen 3.400 N/A SER 84.A OG GLU 115.A OE2 no hydrogen 2.998 N/A SER 84.A OG GLN 141.A OE1 no hydrogen 3.077 N/A VAL 85.A N GLU 114.A O no hydrogen 3.006 N/A TYR 86.A N TYR 138.A O no hydrogen 3.016 N/A SER 87.A N ASN 112.A O no hydrogen 2.953 N/A SER 87.A OG GLU 135.A OE1 no hydrogen 2.924 N/A ALA 88.A N ARG 136.A O no hydrogen 3.139 N/A HIS 91.A NE2 ASP 238.A OD2 no hydrogen 2.867 N/A LYS 92.A N THR 90.A OG1 no hydrogen 3.219 N/A LYS 92.A NZ ASP 236.A OD1 no hydrogen 3.412 N/A LYS 92.A NZ ASP 238.A OD2 no hydrogen 2.723 N/A PHE 93.A N VAL 188.A O no hydrogen 2.755 N/A TYR 96.A OH SER 111.A O no hydrogen 2.675 N/A ASP 97.A N PRO 228.A O no hydrogen 2.769 N/A LYS 99.A N ASP 97.A OD1 no hydrogen 3.017 N/A LYS 100.A N ASP 97.A O no hydrogen 2.970 N/A LYS 100.A NZ VAL 225.A O no hydrogen 2.692 N/A MET 101.A N GLU 98.A O no hydrogen 3.166 N/A ASN 103.A N LYS 100.A O no hydrogen 3.432 N/A PHE 104.A N MET 101.A O no hydrogen 3.059 N/A PHE 107.A N PHE 104.A O no hydrogen 2.891 N/A ASN 112.A N SER 87.A O no hydrogen 2.975 N/A ARG 113.A NE GLU 98.A OE2 no hydrogen 3.133 N/A ARG 113.A NH1 GLU 115.A OE2 no hydrogen 2.846 N/A ARG 113.A NH2 GLU 98.A OE1 no hydrogen 3.141 N/A GLU 114.A N VAL 85.A O no hydrogen 3.019 N/A MET 116.A N PHE 83.A O no hydrogen 3.083 N/A LYS 117.A N GLU 120.A OE1 no hydrogen 2.928 N/A LYS 117.A NZ ASN 80.A O no hydrogen 2.465 N/A LYS 117.A NZ ASP 82.A OD1 no hydrogen 3.145 N/A HIS 119.A ND1 GLU 123.A OE2 no hydrogen 2.655 N/A GLU 120.A N LYS 117.A O no hydrogen 2.848 N/A PHE 121.A N LYS 117.A O no hydrogen 3.176 N/A VAL 122.A N PHE 118.A O no hydrogen 3.003 N/A GLU 123.A N HIS 119.A O no hydrogen 2.977 N/A LYS 124.A N GLU 120.A O no hydrogen 2.941 N/A LYS 124.A NZ GLU 114.A OE1 no hydrogen 3.349 N/A LEU 125.A N PHE 121.A O no hydrogen 3.136 N/A GLN 126.A N VAL 122.A O no hydrogen 3.137 N/A GLN 126.A NE2 GLN 130.A OE1 no hydrogen 3.044 N/A ASP 127.A N GLU 123.A O no hydrogen 2.703 N/A ILE 128.A N LYS 124.A O no hydrogen 2.819 N/A GLN 129.A N LEU 125.A O no hydrogen 2.874 N/A GLN 130.A N GLN 126.A O no hydrogen 2.959 N/A ARG 131.A N ASP 127.A O no hydrogen 3.295 N/A ARG 131.A NH2 GLU 135.A OE2 no hydrogen 3.320 N/A GLY 132.A N GLN 129.A O no hydrogen 3.213 N/A GLY 133.A N ILE 128.A O no hydrogen 3.027 N/A ARG 136.A N ALA 88.A O no hydrogen 3.198 N/A ARG 136.A NH1 GLU 185.A O no hydrogen 2.876 N/A ARG 136.A NH1 ASN 187.A OD1 no hydrogen 3.406 N/A TYR 138.A N TYR 86.A O no hydrogen 2.993 N/A LEU 139.A N ILE 182.A O no hydrogen 2.859 N/A GLN 140.A N SER 84.A O no hydrogen 3.186 N/A GLN 141.A N LEU 180.A O no hydrogen 3.128 N/A GLN 141.A NE2 THR 142.A O no hydrogen 2.861 N/A LEU 143.A N ASN 178.A O no hydrogen 2.905 N/A THR 146.A N ASN 144.A OD1 no hydrogen 3.089 N/A THR 146.A OG1 ASN 144.A OD1 no hydrogen 3.298 N/A VAL 152.A N GLY 148.A O no hydrogen 3.052 N/A MET 153.A N ARG 149.A O no hydrogen 2.868 N/A ASP 154.A N LYS 150.A O no hydrogen 2.968 N/A PHE 155.A N ILE 151.A O no hydrogen 2.992 N/A LEU 156.A N VAL 152.A O no hydrogen 3.024 N/A GLY 157.A N MET 153.A O no hydrogen 3.077 N/A PHE 158.A N PHE 155.A O no hydrogen 3.145 N/A ASN 159.A N LEU 62.A O no hydrogen 2.868 N/A ASN 159.A ND2 THR 60.A O no hydrogen 2.892 N/A TRP 160.A N PHE 158.A O no hydrogen 2.858 N/A TRP 160.A NE1 PHE 155.A O no hydrogen 2.923 N/A TRP 162.A N ASN 159.A O no hydrogen 3.109 N/A TRP 162.A N ASN 159.A OD1 no hydrogen 2.921 N/A ILE 163.A N ASN 159.A O no hydrogen 3.237 N/A ASN 164.A N TRP 160.A O no hydrogen 2.828 N/A GLN 166.A N TRP 162.A O no hydrogen 3.171 N/A GLN 166.A NE2 GLU 46.A OE1 no hydrogen 3.320 N/A GLN 166.A NE2 GLU 46.A OE2 no hydrogen 3.388 N/A GLN 167.A N ILE 163.A O no hydrogen 2.786 N/A GLN 167.A NE2 GLY 173.A O no hydrogen 2.845 N/A GLY 168.A N ASN 164.A O no hydrogen 3.000 N/A LYS 169.A N LYS 165.A O no hydrogen 2.804 N/A LYS 169.A NZ GLU 46.A OE2 no hydrogen 2.487 N/A ARG 170.A N GLN 166.A O no hydrogen 2.952 N/A ARG 170.A NE GLN 166.A OE1 no hydrogen 3.075 N/A ARG 170.A NH1 GLU 50.A OE1 no hydrogen 2.872 N/A ARG 170.A NH2 GLN 166.A OE1 no hydrogen 3.087 N/A GLY 171.A N GLY 168.A O no hydrogen 3.064 N/A TRP 172.A N GLN 167.A O no hydrogen 3.137 N/A GLY 173.A N LYS 291.A O no hydrogen 2.907 N/A THR 176.A N TRP 289.A O no hydrogen 2.663 N/A THR 176.A OG1 SER 177.A OG no hydrogen 3.164 N/A THR 176.A OG1 GLN 196.A OE1 no hydrogen 3.568 N/A SER 177.A OG THR 176.A OG1 no hydrogen 3.164 N/A ASN 178.A ND2 ASN 287.A O no hydrogen 2.877 N/A LEU 179.A N ASN 287.A OD1 no hydrogen 2.800 N/A LEU 180.A N GLN 141.A O no hydrogen 2.919 N/A LEU 181.A N THR 285.A O no hydrogen 2.896 N/A ILE 182.A N LEU 139.A O no hydrogen 2.945 N/A GLY 183.A N THR 283.A O no hydrogen 3.130 N/A GLY 186.A N SER 276.A O no hydrogen 2.749 N/A GLY 186.A N LEU 277.A O no hydrogen 3.277 N/A ASN 187.A N MET 184.A O no hydrogen 2.990 N/A ASN 187.A ND2 LEU 137.A O no hydrogen 2.869 N/A VAL 188.A N HIS 91.A O no hydrogen 2.914 N/A THR 189.A N ILE 274.A O no hydrogen 2.816 N/A HIS 192.A N HIS 272.A O no hydrogen 3.011 N/A HIS 192.A ND1 GLN 232.A OE1 no hydrogen 2.781 N/A TYR 193.A N ARG 231.A O no hydrogen 3.058 N/A GLN 197.A N TYR 290.A O no hydrogen 2.862 N/A GLN 197.A NE2 GLU 52.A OE2 no hydrogen 2.749 N/A ASN 198.A N ILE 266.A O no hydrogen 3.275 N/A PHE 199.A N PHE 288.A O no hydrogen 3.125 N/A PHE 200.A N LEU 264.A O no hydrogen 2.921 N/A ALA 201.A N VAL 286.A O no hydrogen 2.883 N/A GLN 202.A N ASP 262.A O no hydrogen 2.905 N/A GLN 202.A NE2 GLY 205.A O no hydrogen 3.012 N/A ILE 203.A N ILE 284.A O no hydrogen 3.006 N/A LYS 204.A N ILE 284.A O no hydrogen 3.190 N/A TYR 206.A OH GLU 12.A OE2 no hydrogen 2.530 N/A LYS 207.A N VAL 258.A O no hydrogen 3.049 N/A LYS 207.A NZ TYR 138.A OH no hydrogen 3.004 N/A LYS 207.A NZ THR 285.A OG1 no hydrogen 2.979 N/A ARG 208.A N GLU 275.A O no hydrogen 2.827 N/A ARG 208.A NE GLU 255.A OE2 no hydrogen 2.679 N/A ARG 208.A NH1 ARG 26.A O no hydrogen 2.819 N/A ARG 208.A NH1 GLU 275.A OE2 no hydrogen 3.361 N/A ARG 208.A NH2 GLU 255.A OE1 no hydrogen 2.837 N/A ARG 208.A NH2 GLU 255.A OE2 no hydrogen 3.283 N/A CYS 209.A N THR 256.A O no hydrogen 2.850 N/A ILE 210.A N HIS 273.A O no hydrogen 2.803 N/A LEU 211.A N TYR 254.A O no hydrogen 2.674 N/A PHE 212.A N TRP 271.A O no hydrogen 2.987 N/A GLN 216.A N PRO 213.A O no hydrogen 2.988 N/A PHE 217.A N PRO 214.A O no hydrogen 3.135 N/A GLU 218.A N GLU 218.A OE1 no hydrogen 2.470 N/A CYS 219.A N GLN 216.A O no hydrogen 2.906 N/A LEU 220.A N PHE 217.A O no hydrogen 3.148 N/A TYR 221.A N PHE 217.A O no hydrogen 3.399 N/A TYR 223.A N GLN 232.A O no hydrogen 3.199 N/A VAL 225.A N GLU 316.A OE1 no hydrogen 3.186 N/A HIS 226.A NE2 GLU 316.A O no hydrogen 3.047 N/A HIS 227.A N PRO 224.A O no hydrogen 2.957 N/A CYS 229.A N HIS 227.A ND1 no hydrogen 2.945 N/A CYS 229.A SG TYR 95.A O no hydrogen 3.658 N/A ASP 230.A N HIS 227.A O no hydrogen 3.025 N/A ARG 231.A NE TYR 193.A O no hydrogen 3.284 N/A GLN 232.A N CYS 229.A O no hydrogen 2.872 N/A GLN 232.A NE2 ASP 230.A O no hydrogen 2.774 N/A SER 233.A N ALA 191.A O no hydrogen 2.958 N/A SER 233.A OG LEU 220.A O no hydrogen 2.621 N/A GLN 234.A N TYR 221.A O no hydrogen 2.935 N/A GLN 234.A NE2 TYR 221.A O no hydrogen 2.915 N/A GLN 234.A NE2 PRO 222.A O no hydrogen 3.356 N/A VAL 235.A N SER 233.A OG no hydrogen 3.077 N/A ASP 238.A N ASP 236.A OD1 no hydrogen 2.826 N/A ASN 239.A N ASP 236.A O no hydrogen 2.901 N/A TYR 242.A OH SER 29.A OG no hydrogen 3.213 N/A GLU 243.A N ASP 241.A OD1 no hydrogen 2.962 N/A ARG 244.A N ASP 241.A OD1 no hydrogen 3.010 N/A PHE 245.A N ASP 241.A O no hydrogen 2.812 N/A ASN 247.A N TYR 221.A OH no hydrogen 2.858 N/A ASN 247.A ND2 ASN 250.A OD1 no hydrogen 2.932 N/A PHE 248.A N PHE 245.A O no hydrogen 2.967 N/A GLN 249.A N PRO 246.A O no hydrogen 3.181 N/A GLN 249.A NE2 PRO 246.A O no hydrogen 3.003 N/A ASN 250.A N ASN 247.A O no hydrogen 2.956 N/A VAL 251.A N PHE 248.A O no hydrogen 3.411 N/A VAL 252.A N GLN 216.A OE1 no hydrogen 2.932 N/A GLY 253.A N PRO 31.A O no hydrogen 3.065 N/A TYR 254.A N LEU 211.A O no hydrogen 2.760 N/A GLU 255.A N ARG 33.A O no hydrogen 2.823 N/A THR 256.A N CYS 209.A O no hydrogen 3.139 N/A VAL 258.A N LYS 207.A O no hydrogen 2.842 N/A GLY 259.A N ASP 262.A OD2 no hydrogen 2.729 N/A GLY 261.A N GLN 202.A O no hydrogen 3.045 N/A ASP 262.A N GLY 259.A O no hydrogen 2.870 N/A VAL 263.A N LEU 57.A O no hydrogen 2.984 N/A LEU 264.A N PHE 200.A O no hydrogen 2.927 N/A TYR 265.A N VAL 55.A O no hydrogen 3.063 N/A TYR 265.A OH GLN 197.A OE1 no hydrogen 2.811 N/A ILE 266.A N ASN 198.A O no hydrogen 2.852 N/A MET 268.A N GLN 197.A OE1 no hydrogen 2.959 N/A TYR 269.A N ASP 194.A O no hydrogen 3.036 N/A TYR 269.A OH GLU 195.A OE2 no hydrogen 3.186 N/A TRP 270.A N PRO 267.A O no hydrogen 3.090 N/A TRP 271.A N PHE 212.A O no hydrogen 2.957 N/A HIS 272.A N HIS 192.A O no hydrogen 2.760 N/A HIS 272.A ND1 TRP 270.A O no hydrogen 2.952 N/A HIS 272.A NE2 ASP 194.A OD2 no hydrogen 2.977 N/A HIS 273.A N ILE 210.A O no hydrogen 2.741 N/A HIS 273.A NE2 GLU 275.A OE1 no hydrogen 2.793 N/A ILE 274.A N THR 189.A O no hydrogen 3.328 N/A GLU 275.A N ARG 208.A O no hydrogen 3.061 N/A SER 276.A N ASN 187.A O no hydrogen 2.837 N/A SER 276.A OG THR 283.A OG1 no hydrogen 2.739 N/A LEU 277.A N TYR 206.A O no hydrogen 3.309 N/A LEU 278.A N GLN 24.A O no hydrogen 2.980 N/A GLY 281.A N GLU 185.A OE1 no hydrogen 2.995 N/A THR 283.A N GLY 183.A O no hydrogen 2.936 N/A THR 283.A OG1 GLY 183.A O no hydrogen 3.473 N/A THR 283.A OG1 SER 276.A OG no hydrogen 2.739 N/A ILE 284.A N LYS 204.A O no hydrogen 2.946 N/A THR 285.A N LEU 181.A O no hydrogen 3.010 N/A THR 285.A OG1 GLN 202.A OE1 no hydrogen 2.674 N/A VAL 286.A N ALA 201.A O no hydrogen 3.029 N/A ASN 287.A N LEU 179.A O no hydrogen 3.062 N/A PHE 288.A N PHE 199.A O no hydrogen 2.808 N/A TRP 289.A N SER 177.A O no hydrogen 3.031 N/A TYR 290.A N GLN 197.A O no hydrogen 2.938 N/A LYS 291.A N GLN 174.A O no hydrogen 3.263 N/A LYS 304.A N GLN 307.A OE1 no hydrogen 2.798 N/A GLN 307.A N LYS 304.A O no hydrogen 3.115 N/A LYS 308.A N LYS 304.A O no hydrogen 3.367 N/A LYS 308.A N ALA 305.A O no hydrogen 2.908 N/A VAL 309.A N ALA 305.A O no hydrogen 3.016 N/A ALA 310.A N HIS 306.A O no hydrogen 3.000 N/A ILE 311.A N GLN 307.A O no hydrogen 3.000 N/A MET 312.A N LYS 308.A O no hydrogen 2.988 N/A ARG 313.A N VAL 309.A O no hydrogen 2.904 N/A ARG 313.A NH1 TYR 193.A OH no hydrogen 2.919 N/A ARG 313.A NH1 ASP 230.A OD1 no hydrogen 2.882 N/A ARG 313.A NH1 ASP 230.A OD2 no hydrogen 3.525 N/A ARG 313.A NH2 ASP 230.A OD2 no hydrogen 2.736 N/A ASN 314.A N ALA 310.A O no hydrogen 2.945 N/A ILE 315.A N ILE 311.A O no hydrogen 2.936 N/A GLU 316.A N MET 312.A O no hydrogen 3.015 N/A LYS 317.A N ARG 313.A O no hydrogen 2.956 N/A MET 318.A N ASN 314.A O no hydrogen 2.882 N/A LEU 319.A N ILE 315.A O no hydrogen 3.000 N/A GLY 320.A N GLU 316.A O no hydrogen 3.167 N/A GLU 321.A N LYS 317.A O no hydrogen 3.153 N/A ALA 322.A N MET 318.A O no hydrogen 2.827 N/A LEU 323.A N LEU 319.A O no hydrogen 2.889 N/A GLY 324.A N GLU 321.A O no hydrogen 3.203 N/A GLN 327.A N ASN 325.A OD1 no hydrogen 3.144 N/A GLN 327.A NE2 ASN 103.A O no hydrogen 2.784 N/A GLU 328.A N ASN 325.A O no hydrogen 3.092 N/A VAL 329.A N PRO 326.A O no hydrogen 3.345 N/A LEU 332.A N GLU 328.A O no hydrogen 3.216 N/A LEU 333.A N VAL 329.A O no hydrogen 3.006 N/A ASN 334.A N GLY 330.A O no hydrogen 2.958 N/A ASN 334.A ND2 GLY 330.A O no hydrogen 3.202 N/A THR 335.A N PRO 331.A O no hydrogen 3.014 N/A THR 335.A OG1 PRO 331.A O no hydrogen 2.971 N/A MET 336.A N LEU 332.A O no hydrogen 2.925 N/A ILE 337.A N LEU 333.A O no hydrogen 3.058 N/A ILE 337.A N ASN 334.A O no hydrogen 3.005 N/A LYS 338.A N ASN 334.A O no hydrogen 2.823 N/A GLY 339.A N ASN 342.A OD1 no hydrogen 3.058 N/A ARG 340.A N ILE 337.A O no hydrogen 2.825 N/A ARG 340.A NH1 MET 336.A O no hydrogen 2.810 N/A TYR 341.A N ILE 337.A O no hydrogen 2.840 N/A