Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2wef_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 4.A N THR 1.A OG1 no hydrogen 3.230 N/A ARG 5.A N THR 1.A O no hydrogen 3.080 N/A ARG 5.A NE GLN 86.A OE1 no hydrogen 2.874 N/A LEU 6.A N VAL 2.A O no hydrogen 2.778 N/A VAL 7.A N LEU 3.A O no hydrogen 2.964 N/A ALA 8.A N MET 4.A O no hydrogen 2.865 N/A SER 9.A N ARG 5.A O no hydrogen 2.954 N/A SER 9.A OG ARG 5.A O no hydrogen 2.832 N/A SER 9.A OG GLN 86.A OE1 no hydrogen 3.314 N/A ALA 10.A N LEU 6.A O no hydrogen 2.726 N/A TYR 11.A N VAL 7.A O no hydrogen 2.944 N/A SER 12.A N ALA 8.A O no hydrogen 3.415 N/A SER 12.A OG ALA 8.A O no hydrogen 3.557 N/A ILE 13.A N SER 9.A O no hydrogen 2.920 N/A ALA 14.A N ALA 10.A O no hydrogen 2.858 N/A GLN 15.A N TYR 11.A O no hydrogen 3.122 N/A LYS 16.A N SER 12.A O no hydrogen 2.997 N/A LYS 16.A NZ GLU 80.A O no hydrogen 2.972 N/A LYS 16.A NZ GLU 80.A OE2 no hydrogen 3.220 N/A ALA 17.A N ILE 13.A O no hydrogen 2.889 N/A GLY 18.A N ALA 14.A O no hydrogen 2.834 N/A MET 19.A N GLN 15.A O no hydrogen 2.921 N/A ILE 20.A N LYS 16.A O no hydrogen 2.955 N/A VAL 21.A N ALA 17.A O no hydrogen 2.892 N/A ARG 22.A N GLY 18.A O no hydrogen 3.001 N/A ARG 22.A NH1 PRO 148.A O no hydrogen 2.875 N/A ARG 23.A N MET 19.A O no hydrogen 2.810 N/A ARG 23.A NH1 GLU 80.A OE1 no hydrogen 3.508 N/A VAL 24.A N ILE 20.A O no hydrogen 2.956 N/A ALA 26.A N ARG 22.A O no hydrogen 2.919 N/A GLU 27.A N ARG 23.A O no hydrogen 2.936 N/A GLY 28.A N VAL 24.A O no hydrogen 3.153 N/A GLY 28.A N ILE 25.A O no hydrogen 3.008 N/A GLY 31.A N ASP 29.A OD1 no hydrogen 3.011 N/A VAL 33.A N GLN 42.A O no hydrogen 2.815 N/A LYS 35.A N ASP 40.A O no hydrogen 2.740 N/A LYS 35.A NZ GLU 70.A OE1 no hydrogen 2.740 N/A THR 36.A N ASP 40.A OD2 no hydrogen 2.848 N/A THR 36.A OG1 ASP 40.A OD2 no hydrogen 2.585 N/A CYS 37.A SG THR 39.A OG1 no hydrogen 3.344 N/A ASP 40.A N CYS 37.A O no hydrogen 3.070 N/A GLN 42.A N VAL 33.A O no hydrogen 2.948 N/A GLN 42.A NE2 GLU 70.A OE1 no hydrogen 2.884 N/A THR 43.A N ASP 46.A OD1 no hydrogen 2.745 N/A THR 43.A OG1 ASP 46.A OD1 no hydrogen 2.725 N/A LYS 44.A N LEU 30.A O no hydrogen 2.797 N/A ALA 45.A N THR 43.A OG1 no hydrogen 3.153 N/A ASP 46.A N THR 43.A OG1 no hydrogen 3.418 N/A ARG 47.A N THR 43.A O no hydrogen 3.109 N/A ARG 47.A NH1 GLY 31.A O no hydrogen 3.416 N/A ARG 47.A NH1 GLN 42.A O no hydrogen 3.398 N/A ARG 47.A NH1 GLN 42.A OE1 no hydrogen 2.978 N/A ARG 47.A NH2 GLY 31.A O no hydrogen 2.880 N/A LEU 48.A N LYS 44.A O no hydrogen 2.932 N/A ALA 49.A N ALA 45.A O no hydrogen 2.857 N/A GLN 50.A N ASP 46.A O no hydrogen 3.065 N/A GLN 50.A NE2 GLU 70.A O no hydrogen 2.936 N/A MET 51.A N ARG 47.A O no hydrogen 2.938 N/A SER 52.A N LEU 48.A O no hydrogen 2.889 N/A SER 52.A OG LEU 81.A O no hydrogen 2.609 N/A ILE 53.A N ALA 49.A O no hydrogen 2.836 N/A CYS 54.A N GLN 50.A O no hydrogen 2.934 N/A SER 55.A N MET 51.A O no hydrogen 3.003 N/A SER 55.A OG MET 51.A O no hydrogen 2.875 N/A SER 56.A N SER 52.A O no hydrogen 2.996 N/A SER 56.A OG SER 52.A O no hydrogen 2.716 N/A LEU 57.A N ILE 53.A O no hydrogen 2.954 N/A ALA 58.A N CYS 54.A O no hydrogen 2.840 N/A ARG 59.A N.A SER 55.A O no hydrogen 2.987 N/A ARG 59.A N.B SER 55.A O no hydrogen 2.988 N/A ARG 59.A NH1.A GLN 79.A OE1 no hydrogen 3.469 N/A ARG 59.A NH2.A GLN 79.A OE1 no hydrogen 2.679 N/A LYS 60.A N SER 56.A O no hydrogen 3.391 N/A LYS 60.A NZ SER 9.A OG no hydrogen 3.103 N/A LYS 60.A NZ ASP 84.A O.A no hydrogen 2.874 N/A LYS 60.A NZ ASP 84.A O.B no hydrogen 2.965 N/A LYS 60.A NZ SER 85.A O no hydrogen 3.350 N/A LYS 60.A NZ GLN 86.A OE1 no hydrogen 3.020 N/A PHE 61.A N LEU 57.A O no hydrogen 2.757 N/A LYS 63.A N GLU 104.A OE2 no hydrogen 2.847 N/A LYS 63.A NZ GLU 105.A OE2 no hydrogen 3.544 N/A LEU 64.A N PHE 61.A O no hydrogen 3.111 N/A THR 65.A N LEU 107.A O no hydrogen 3.457 N/A ILE 67.A N VAL 109.A O no hydrogen 2.744 N/A GLU 69.A N VAL 111.A O no hydrogen 3.046 N/A GLU 70.A N GLN 50.A OE1 no hydrogen 2.909 N/A GLN 79.A NE2 VAL 77.A O no hydrogen 3.034 N/A GLU 80.A N ASP 78.A OD1 no hydrogen 3.156 N/A LEU 81.A N ASP 78.A O no hydrogen 2.853 N/A ILE 82.A N GLN 79.A O no hydrogen 3.196 N/A GLU 83.A N SER 56.A OG no hydrogen 2.862 N/A SER 85.A N GLU 83.A OE2 no hydrogen 2.875 N/A SER 85.A OG GLU 83.A OE2 no hydrogen 3.087 N/A GLN 86.A NE2 GLU 88.A OE2 no hydrogen 3.407 N/A TRP 87.A N ALA 8.A O no hydrogen 3.152 N/A ILE 90.A N TRP 87.A O no hydrogen 3.149 N/A LYS 92.A N GLU 89.A O no hydrogen 3.311 N/A LYS 92.A NZ GLU 89.A OE2 no hydrogen 2.583 N/A GLN 93.A N ILE 90.A O no hydrogen 2.994 N/A CYS 95.A SG THR 1.A OG1 no hydrogen 3.440 N/A CYS 95.A SG PRO 96.A O no hydrogen 3.518 N/A TYR 99.A N PRO 96.A O no hydrogen 2.938 N/A SER 100.A N SER 97.A O no hydrogen 3.206 N/A SER 100.A OG SER 97.A O no hydrogen 2.811 N/A ILE 102.A N TYR 99.A O no hydrogen 3.309 N/A GLU 105.A N GLU 105.A OE1 no hydrogen 2.722 N/A ASP 106.A N LYS 103.A O no hydrogen 2.910 N/A LEU 107.A N GLU 104.A O no hydrogen 3.109 N/A VAL 108.A N ALA 135.A O no hydrogen 2.960 N/A VAL 109.A N THR 65.A O no hydrogen 2.770 N/A TRP 110.A N GLY 133.A O no hydrogen 2.818 N/A TRP 110.A NE1 TYR 267.A O no hydrogen 3.001 N/A VAL 111.A N ILE 67.A O no hydrogen 2.844 N/A ASP 112.A N LEU 131.A O no hydrogen 2.957 N/A LEU 114.A N ASP 112.A OD1 no hydrogen 3.338 N/A ASP 115.A N THR 129.A O no hydrogen 2.757 N/A THR 117.A OG1 ASP 46.A OD2 no hydrogen 2.548 N/A THR 117.A OG1 LEU 114.A O no hydrogen 3.265 N/A LYS 118.A NZ ALA 38.A O no hydrogen 3.078 N/A TYR 120.A N GLY 116.A O no hydrogen 2.894 N/A TYR 120.A OH VAL 21.A O no hydrogen 2.720 N/A THR 121.A N THR 117.A O no hydrogen 2.939 N/A THR 121.A OG1 LYS 118.A O no hydrogen 2.621 N/A GLU 122.A N GLU 119.A O no hydrogen 3.068 N/A GLY 123.A N TYR 120.A O no hydrogen 3.254 N/A LEU 124.A N GLU 119.A O no hydrogen 2.871 N/A ASN 127.A N LEU 124.A O no hydrogen 3.130 N/A VAL 128.A N LEU 125.A O no hydrogen 3.251 N/A THR 129.A N ASP 115.A O no hydrogen 2.993 N/A VAL 130.A N ASN 146.A O no hydrogen 2.812 N/A LEU 131.A N ASP 112.A O no hydrogen 2.921 N/A ILE 132.A N VAL 144.A O no hydrogen 2.953 N/A GLY 133.A N TRP 110.A O no hydrogen 2.936 N/A ILE 134.A N ALA 142.A O no hydrogen 2.838 N/A ALA 135.A N VAL 108.A O no hydrogen 2.855 N/A TYR 136.A N LYS 139.A O no hydrogen 2.841 N/A LYS 139.A N TYR 136.A O no hydrogen 3.033 N/A ILE 141.A N ILE 134.A O no hydrogen 2.814 N/A ALA 142.A N ILE 134.A O no hydrogen 3.297 N/A GLY 143.A N GLY 166.A O no hydrogen 2.901 N/A VAL 144.A N ILE 132.A O no hydrogen 2.834 N/A ILE 145.A N ILE 164.A O no hydrogen 2.877 N/A ASN 146.A N VAL 130.A O no hydrogen 2.963 N/A ASN 146.A ND2 THR 163.A OG1 no hydrogen 2.877 N/A GLN 147.A N ARG 162.A O no hydrogen 2.777 N/A GLN 147.A NE2 ASP 126.A O no hydrogen 2.949 N/A TYR 150.A N GLN 147.A O no hydrogen 3.105 N/A ASN 151.A ND2 VAL 159.A O no hydrogen 2.983 N/A TYR 152.A N TYR 149.A O no hydrogen 2.935 N/A ALA 154.A N ASN 151.A O no hydrogen 2.980 N/A ALA 158.A N GLY 155.A O no hydrogen 3.327 N/A GLY 161.A N TYR 150.A O no hydrogen 2.911 N/A ARG 162.A N GLN 147.A O no hydrogen 3.128 N/A ARG 162.A NE GLN 147.A OE1 no hydrogen 2.926 N/A ARG 162.A NH1 GLU 225.A OE2 no hydrogen 2.803 N/A ARG 162.A NH2 GLN 147.A OE1 no hydrogen 2.899 N/A ARG 162.A NH2 GLU 225.A OE1 no hydrogen 3.058 N/A ILE 164.A N ILE 145.A O no hydrogen 2.827 N/A TRP 165.A N PHE 173.A O no hydrogen 3.100 N/A GLY 166.A N GLY 143.A O no hydrogen 2.909 N/A VAL 167.A N GLY 171.A O no hydrogen 3.127 N/A LEU 168.A N ILE 141.A O no hydrogen 2.964 N/A LEU 170.A N VAL 167.A O no hydrogen 2.797 N/A GLY 171.A N VAL 167.A O no hydrogen 3.014 N/A PHE 173.A N TRP 165.A O no hydrogen 2.814 N/A LYS 178.A N ILE 224.A O no hydrogen 3.019 N/A LYS 184.A N PRO 181.A O no hydrogen 3.233 N/A HIS 185.A N ASP 208.A OD2 no hydrogen 2.781 N/A HIS 185.A ND1 TYR 289.A OH no hydrogen 2.895 N/A ILE 186.A N SER 229.A OG no hydrogen 3.026 N/A ILE 187.A N ALA 209.A O no hydrogen 2.893 N/A THR 188.A N ALA 230.A O no hydrogen 2.840 N/A THR 188.A OG1 GLN 222.A OE1 no hydrogen 2.678 N/A THR 189.A N LEU 211.A O no hydrogen 2.993 N/A THR 189.A OG1 VAL 232.A O no hydrogen 2.748 N/A ARG 191.A NH1 ARG 212.A O no hydrogen 2.977 N/A SER 192.A OG GLU 119.A OE2 no hydrogen 2.736 N/A HIS 193.A N THR 190.A OG1 no hydrogen 2.786 N/A HIS 193.A NE2 THR 39.A O no hydrogen 2.858 N/A LYS 196.A NZ ASP 200.A OD2 no hydrogen 2.772 N/A VAL 198.A N ASN 195.A OD1 no hydrogen 2.988 N/A THR 199.A N ASN 195.A O no hydrogen 3.095 N/A THR 199.A OG1 ASN 195.A O no hydrogen 3.321 N/A THR 199.A OG1 LYS 196.A O no hydrogen 3.227 N/A ASP 200.A N LYS 196.A O no hydrogen 2.870 N/A CYS 201.A N LEU 197.A O no hydrogen 2.929 N/A VAL 202.A N VAL 198.A O no hydrogen 3.060 N/A ALA 203.A N THR 199.A O no hydrogen 2.902 N/A ALA 204.A N ASP 200.A O no hydrogen 3.032 N/A MET 205.A N VAL 202.A O no hydrogen 3.047 N/A ASN 206.A N ALA 203.A O no hydrogen 3.055 N/A ASP 208.A N HIS 185.A O no hydrogen 2.707 N/A ALA 209.A N HIS 185.A O no hydrogen 3.360 N/A LEU 211.A N ILE 187.A O no hydrogen 2.786 N/A VAL 213.A N THR 189.A O no hydrogen 3.228 N/A GLY 217.A N ASP 115.A OD2 no hydrogen 3.062 N/A ASN 218.A ND2 GLY 214.A O no hydrogen 3.086 N/A LYS 219.A N GLY 215.A O no hydrogen 3.210 N/A LYS 219.A NZ VAL 213.A O no hydrogen 2.740 N/A LYS 219.A NZ GLY 215.A O no hydrogen 2.918 N/A ILE 220.A N ALA 216.A O no hydrogen 3.147 N/A ILE 221.A N GLY 217.A O no hydrogen 3.031 N/A GLN 222.A N ASN 218.A O no hydrogen 2.935 N/A LEU 223.A N LYS 219.A O no hydrogen 3.262 N/A LEU 223.A N ILE 220.A O no hydrogen 2.992 N/A ILE 224.A N ILE 220.A O no hydrogen 3.141 N/A GLU 225.A N ILE 221.A O no hydrogen 3.040 N/A GLY 226.A N LEU 223.A O no hydrogen 3.350 N/A LYS 227.A N GLN 222.A O no hydrogen 2.865 N/A ALA 228.A N GLN 222.A O no hydrogen 3.291 N/A SER 229.A N ILE 186.A O no hydrogen 2.708 N/A SER 229.A OG ILE 186.A O no hydrogen 3.207 N/A SER 229.A OG TYR 289.A OH no hydrogen 2.513 N/A ALA 230.A N ILE 186.A O no hydrogen 3.148 N/A TYR 231.A N ALA 281.A O no hydrogen 2.862 N/A VAL 232.A N THR 188.A O no hydrogen 3.101 N/A PHE 233.A N VAL 279.A O no hydrogen 2.838 N/A SER 235.A N PHE 233.A O no hydrogen 3.000 N/A SER 235.A OG PRO 236.A O no hydrogen 2.535 N/A LYS 239.A N ASP 242.A OD2 no hydrogen 2.858 N/A LYS 240.A N HIS 273.A O no hydrogen 2.856 N/A LYS 240.A NZ LYS 272.A O no hydrogen 2.912 N/A LYS 240.A NZ ASN 275.A OD1 no hydrogen 2.842 N/A ASP 242.A N LYS 239.A O no hydrogen 2.919 N/A THR 243.A N LYS 240.A O no hydrogen 3.235 N/A THR 243.A OG1 LYS 240.A O no hydrogen 3.490 N/A THR 243.A OG1 TYR 267.A OH no hydrogen 2.829 N/A CYS 244.A N LYS 240.A O no hydrogen 2.915 N/A GLU 247.A N THR 243.A O no hydrogen 2.904 N/A VAL 248.A N CYS 244.A O no hydrogen 3.354 N/A ILE 249.A N ALA 245.A O no hydrogen 3.296 N/A LEU 250.A N PRO 246.A O no hydrogen 2.957 N/A HIS 251.A N GLU 247.A O no hydrogen 2.821 N/A ALA 252.A N VAL 248.A O no hydrogen 2.890 N/A VAL 253.A N LEU 250.A O no hydrogen 3.155 N/A GLY 254.A N HIS 251.A O no hydrogen 2.903 N/A GLY 255.A N LEU 250.A O no hydrogen 2.917 N/A LYS 256.A N THR 282.A O no hydrogen 2.981 N/A THR 258.A N LEU 280.A O no hydrogen 2.849 N/A THR 258.A OG1 ASP 259.A O no hydrogen 2.755 N/A THR 258.A OG1 TYR 286.A OH no hydrogen 2.661 N/A ASP 259.A N ASN 263.A O no hydrogen 2.851 N/A ILE 260.A N ALA 277.A O no hydrogen 2.927 N/A HIS 261.A NE2 LYS 298.A O no hydrogen 2.918 N/A GLY 262.A N ASP 259.A O no hydrogen 3.001 N/A ASN 263.A N ASP 259.A OD1 no hydrogen 2.960 N/A ASN 263.A ND2 ASP 259.A OD2 no hydrogen 3.324 N/A TYR 267.A N GLY 138.A O no hydrogen 2.919 N/A TYR 267.A OH THR 243.A OG1 no hydrogen 2.829 N/A TYR 267.A OH GLU 247.A OE1 no hydrogen 2.688 N/A VAL 271.A N HIS 268.A O no hydrogen 3.039 N/A LYS 272.A NZ SER 276.A OG no hydrogen 2.769 N/A ASN 275.A N CYS 238.A O no hydrogen 2.927 N/A ASN 275.A ND2 THR 243.A OG1 no hydrogen 3.210 N/A SER 276.A OG VAL 302.A O no hydrogen 2.679 N/A SER 276.A OG PRO 303.A O no hydrogen 2.998 N/A GLY 278.A N ASN 275.A O no hydrogen 3.344 N/A VAL 279.A N PHE 233.A O no hydrogen 2.993 N/A LEU 280.A N THR 258.A O no hydrogen 2.874 N/A ALA 281.A N TYR 231.A O no hydrogen 2.988 N/A THR 282.A N LYS 256.A O no hydrogen 2.931 N/A ARG 284.A NE GLU 179.A OE2 no hydrogen 3.547 N/A ARG 284.A NH1 VAL 253.A O no hydrogen 2.870 N/A ARG 284.A NH1 LEU 283.A O no hydrogen 2.944 N/A ARG 284.A NH2 VAL 253.A O no hydrogen 3.169 N/A TYR 286.A OH THR 258.A OG1 no hydrogen 2.661 N/A TYR 288.A N ASN 285.A O no hydrogen 3.188 N/A TYR 288.A OH MET 205.A O no hydrogen 2.868 N/A ALA 290.A N TYR 286.A O no hydrogen 2.947 N/A SER 291.A N ASP 287.A O no hydrogen 3.000 N/A SER 291.A OG ASP 287.A O no hydrogen 2.922 N/A SER 291.A OG TYR 288.A O no hydrogen 3.177 N/A ARG 292.A N TYR 289.A O no hydrogen 2.954 N/A ARG 292.A NH1 TYR 288.A O no hydrogen 2.976 N/A VAL 293.A N ALA 290.A O no hydrogen 3.435 N/A ILE 297.A N PRO 294.A O no hydrogen 3.040 N/A LYS 298.A N PRO 294.A O no hydrogen 3.151 N/A LYS 298.A NZ GLU 295.A OE2 no hydrogen 2.828 N/A ASN 299.A N GLU 295.A O no hydrogen 2.833 N/A ALA 300.A N SER 296.A O no hydrogen 3.146 N/A ALA 300.A N ILE 297.A O no hydrogen 3.075 N/A LEU 301.A N LYS 298.A O no hydrogen 3.369 N/A