Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2wl4_C.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 3.A N MET 256.A O no hydrogen 2.562 N/A ILE 4.A N GLY 270.A O no hydrogen 2.902 N/A ALA 5.A N LEU 254.A O no hydrogen 3.129 N/A SER 6.A OG VAL 35.A O no hydrogen 2.702 N/A ALA 8.A N ALA 252.A O no hydrogen 3.427 N/A ARG 9.A N GLU 195.A O no hydrogen 3.446 N/A ARG 9.A NH1 THR 10.A O no hydrogen 2.571 N/A ARG 9.A NH1 ASP 213.A OD1 no hydrogen 3.434 N/A ARG 9.A NH2 GLU 195.A OE2 no hydrogen 2.933 N/A ARG 9.A NH2 ASP 213.A OD2 no hydrogen 3.315 N/A THR 10.A N ALA 250.A O no hydrogen 2.703 N/A THR 10.A OG1 ALA 11.A O no hydrogen 2.601 N/A THR 10.A OG1 ALA 250.A O no hydrogen 3.404 N/A VAL 12.A N ASP 213.A OD1 no hydrogen 2.635 N/A GLY 13.A N ASP 248.A O no hydrogen 2.820 N/A SER 14.A N GLU 214.A OE2 no hydrogen 3.049 N/A SER 14.A OG GLU 214.A O no hydrogen 3.174 N/A ASN 16.A N SER 117.A OG no hydrogen 2.815 N/A GLY 17.A N SER 14.A O no hydrogen 2.946 N/A ALA 18.A N GLU 214.A OE2 no hydrogen 2.722 N/A ALA 20.A N GLY 17.A O no hydrogen 3.092 N/A THR 22.A N PHE 19.A O no hydrogen 2.854 N/A HIS 25.A N GLU 59.A OE2 no hydrogen 2.877 N/A HIS 25.A ND1 GLU 59.A OE2 no hydrogen 2.527 N/A GLY 28.A N ALA 24.A O no hydrogen 2.864 N/A ALA 29.A N HIS 25.A O no hydrogen 2.689 N/A THR 30.A N GLU 26.A O no hydrogen 3.066 N/A THR 30.A OG1 GLU 26.A O no hydrogen 3.448 N/A VAL 31.A N LEU 27.A O no hydrogen 3.201 N/A ILE 32.A N GLY 28.A O no hydrogen 2.902 N/A SER 33.A N ALA 29.A O no hydrogen 3.055 N/A ALA 34.A N THR 30.A O no hydrogen 3.056 N/A VAL 35.A N VAL 31.A O no hydrogen 3.308 N/A ARG 38.A NE ALA 34.A O no hydrogen 3.088 N/A GLU 45.A N ALA 42.A O no hydrogen 2.848 N/A VAL 46.A N ALA 43.A O no hydrogen 3.056 N/A ASN 47.A N ILE 107.A O no hydrogen 2.870 N/A VAL 49.A N THR 78.A O no hydrogen 2.836 N/A ILE 50.A N VAL 109.A O no hydrogen 2.728 N/A LEU 51.A N TRP 80.A O no hydrogen 3.102 N/A GLY 52.A N GLY 111.A O no hydrogen 2.732 N/A GLN 53.A N MET 82.A O no hydrogen 2.870 N/A GLN 53.A NE2 GLU 59.A OE1 no hydrogen 2.931 N/A VAL 54.A N GLU 114.A OE1 no hydrogen 2.984 N/A VAL 54.A N GLU 114.A OE2 no hydrogen 3.373 N/A LEU 55.A N GLU 114.A OE2 no hydrogen 2.708 N/A GLU 59.A N PRO 56.A O no hydrogen 3.212 N/A ASN 62.A ND2 ALA 79.A O no hydrogen 2.752 N/A ARG 65.A N ASN 62.A O no hydrogen 2.957 N/A ARG 65.A NH1 ALA 77.A O no hydrogen 3.077 N/A ARG 65.A NH2 GLN 75.A O no hydrogen 3.062 N/A GLN 66.A NE2 GLU 59.A O no hydrogen 2.975 N/A GLN 66.A NE2 GLN 61.A O no hydrogen 3.562 N/A ALA 67.A N PRO 63.A O no hydrogen 2.985 N/A ALA 68.A N ARG 65.A O no hydrogen 3.298 N/A MET 69.A N ARG 65.A O no hydrogen 2.975 N/A LYS 70.A N GLN 66.A O no hydrogen 3.172 N/A ALA 71.A N ALA 67.A O no hydrogen 3.199 N/A GLY 72.A N ALA 68.A O no hydrogen 2.875 N/A VAL 73.A N ALA 68.A O no hydrogen 3.217 N/A ALA 77.A N PRO 74.A O no hydrogen 3.102 N/A THR 78.A N ASN 47.A O no hydrogen 3.031 N/A TRP 80.A N VAL 49.A O no hydrogen 3.064 N/A MET 82.A N LEU 51.A O no hydrogen 3.144 N/A GLN 84.A NE2 THR 277.A OG1 no hydrogen 3.122 N/A LEU 85.A N ASN 83.A OD1 no hydrogen 2.790 N/A GLY 87.A N GLN 84.A O no hydrogen 2.845 N/A SER 88.A N LEU 85.A O no hydrogen 2.860 N/A SER 88.A OG LEU 85.A O no hydrogen 2.805 N/A LEU 90.A N GLY 87.A O no hydrogen 3.151 N/A ARG 91.A N GLY 87.A O no hydrogen 2.915 N/A ARG 91.A NH1 GLN 84.A OE1 no hydrogen 3.153 N/A ALA 92.A N SER 88.A O no hydrogen 2.821 N/A ALA 94.A N LEU 90.A O no hydrogen 3.034 N/A LEU 95.A N ARG 91.A O no hydrogen 2.620 N/A GLY 96.A N ALA 92.A O no hydrogen 2.831 N/A MET 97.A N VAL 93.A O no hydrogen 3.059 N/A MET 97.A N ALA 94.A O no hydrogen 2.823 N/A GLN 98.A N ALA 94.A O no hydrogen 3.334 N/A GLN 99.A NE2 LEU 95.A O no hydrogen 3.554 N/A ALA 101.A N MET 97.A O no hydrogen 2.756 N/A THR 102.A N GLN 98.A O no hydrogen 2.696 N/A THR 102.A OG1 GLN 98.A O no hydrogen 2.615 N/A THR 102.A OG1 GLN 99.A O no hydrogen 3.207 N/A THR 102.A OG1 ASP 104.A OD2 no hydrogen 3.041 N/A ASP 104.A N GLN 99.A O no hydrogen 3.007 N/A ALA 105.A N GLN 99.A O no hydrogen 3.326 N/A SER 106.A N ASN 47.A OD1 no hydrogen 2.492 N/A ILE 107.A N ASN 47.A OD1 no hydrogen 2.919 N/A ILE 108.A N LEU 255.A O no hydrogen 2.940 N/A VAL 109.A N GLU 48.A O no hydrogen 3.018 N/A ALA 110.A N ALA 253.A O no hydrogen 2.853 N/A GLY 111.A N ILE 50.A O no hydrogen 3.026 N/A GLY 112.A N ALA 251.A O no hydrogen 2.624 N/A MET 113.A N GLY 52.A O no hydrogen 3.045 N/A GLU 114.A N GLY 249.A O no hydrogen 2.906 N/A SER 115.A OG THR 22.A O no hydrogen 3.476 N/A SER 117.A N ASP 248.A OD1 no hydrogen 2.836 N/A SER 117.A OG ASP 248.A OD1 no hydrogen 2.776 N/A SER 117.A OG ASP 248.A OD2 no hydrogen 2.510 N/A MET 118.A N SER 115.A O no hydrogen 2.859 N/A MET 118.A N SER 115.A OG no hydrogen 2.803 N/A ALA 119.A N MET 116.A O no hydrogen 3.176 N/A CYS 122.A N ILE 137.A O no hydrogen 2.823 N/A CYS 122.A SG ILE 137.A O no hydrogen 3.848 N/A ILE 137.A N CYS 122.A O no hydrogen 2.809 N/A THR 139.A N PRO 120.A O no hydrogen 3.236 N/A THR 139.A OG1 PRO 120.A O no hydrogen 2.416 N/A LYS 142.A N ASP 138.A O no hydrogen 2.876 N/A ASP 143.A N THR 139.A O no hydrogen 2.760 N/A LEU 145.A N ILE 141.A O no hydrogen 3.005 N/A THR 146.A OG1 ILE 141.A O no hydrogen 2.602 N/A ASP 147.A N TYR 152.A O no hydrogen 2.966 N/A GLY 151.A N ASP 147.A O no hydrogen 2.777 N/A MET 154.A N LEU 145.A O no hydrogen 2.945 N/A GLY 155.A N HIS 153.A ND1 no hydrogen 2.936 N/A THR 156.A N HIS 153.A O no hydrogen 2.959 N/A THR 157.A OG1 MET 154.A O no hydrogen 2.768 N/A ALA 158.A N MET 154.A O no hydrogen 3.094 N/A GLU 159.A N GLY 155.A O no hydrogen 3.224 N/A ASN 160.A N THR 156.A O no hydrogen 2.978 N/A ASN 160.A ND2 TYR 152.A OH no hydrogen 3.554 N/A ASN 160.A ND2 LYS 283.A O no hydrogen 2.904 N/A VAL 161.A N THR 157.A O no hydrogen 3.038 N/A ALA 162.A N ALA 158.A O no hydrogen 2.898 N/A LYS 163.A N GLU 159.A O no hydrogen 2.702 N/A GLN 164.A N ASN 160.A O no hydrogen 2.933 N/A TRP 165.A N VAL 161.A O no hydrogen 2.690 N/A LEU 167.A N ALA 162.A O no hydrogen 3.206 N/A ARG 169.A NE ASP 173.A OD1 no hydrogen 3.414 N/A ARG 169.A NE ASP 173.A OD2 no hydrogen 2.853 N/A ARG 169.A NH1 LEU 228.A O no hydrogen 3.543 N/A ARG 169.A NH2 MET 225.A O no hydrogen 3.227 N/A ARG 169.A NH2 LEU 228.A O no hydrogen 2.875 N/A GLN 172.A N SER 168.A O no hydrogen 3.204 N/A GLN 172.A NE2 LEU 167.A O no hydrogen 2.834 N/A ASP 173.A N ARG 169.A O no hydrogen 3.066 N/A ALA 174.A N ASP 170.A O no hydrogen 2.704 N/A PHE 175.A N GLU 171.A O no hydrogen 2.923 N/A ALA 176.A N GLN 172.A O no hydrogen 2.822 N/A VAL 177.A N ASP 173.A O no hydrogen 2.883 N/A ALA 178.A N ALA 174.A O no hydrogen 3.350 N/A SER 179.A N PHE 175.A O no hydrogen 3.114 N/A SER 179.A OG GLU 314.A OE1 no hydrogen 3.042 N/A GLN 180.A N ALA 176.A O no hydrogen 3.235 N/A ASN 181.A N VAL 177.A O no hydrogen 3.108 N/A ASN 181.A ND2 ALA 220.A O no hydrogen 3.426 N/A LYS 182.A N ALA 178.A O no hydrogen 2.925 N/A LYS 182.A NZ ASN 335.A O no hydrogen 2.829 N/A ALA 183.A N SER 179.A O no hydrogen 2.663 N/A GLU 184.A N GLN 180.A O no hydrogen 2.921 N/A ALA 185.A N ASN 181.A O no hydrogen 2.941 N/A ALA 186.A N LYS 182.A O no hydrogen 2.880 N/A GLN 187.A N ALA 183.A O no hydrogen 3.113 N/A GLN 187.A NE2 ASP 213.A O no hydrogen 2.998 N/A LYS 188.A N GLU 184.A O no hydrogen 3.342 N/A ASP 189.A N ALA 185.A O no hydrogen 3.016 N/A GLY 190.A N GLN 187.A O no hydrogen 2.893 N/A ARG 191.A N ALA 186.A O no hydrogen 2.760 N/A ARG 191.A NE ASN 337.A OD1.A no hydrogen 3.034 N/A ARG 191.A NE ASN 337.A OD1.B no hydrogen 3.018 N/A ARG 191.A NH1 ASP 189.A OD2 no hydrogen 3.182 N/A LYS 193.A N GLY 190.A O no hydrogen 3.089 N/A ILE 196.A N PHE 192.A O no hydrogen 3.219 N/A VAL 197.A N ARG 9.A O no hydrogen 2.836 N/A PHE 199.A N VAL 210.A O no hydrogen 3.153 N/A VAL 201.A N ILE 208.A O no hydrogen 3.056 N/A LYS 202.A NZ ASP 207.A OD2 no hydrogen 2.873 N/A GLY 203.A N ASP 207.A OD1 no hydrogen 2.902 N/A ILE 208.A N VAL 201.A O no hydrogen 3.299 N/A VAL 210.A N PHE 199.A O no hydrogen 3.097 N/A GLU 214.A N VAL 12.A O no hydrogen 3.293 N/A ARG 217.A N GLN 180.A OE1 no hydrogen 2.994 N/A ASP 223.A N THR 221.A OG1 no hydrogen 3.067 N/A SER 224.A N THR 221.A OG1 no hydrogen 2.761 N/A SER 224.A OG THR 221.A O no hydrogen 3.267 N/A MET 225.A N THR 221.A O no hydrogen 3.141 N/A LYS 227.A N SER 224.A O no hydrogen 3.387 N/A LEU 228.A N MET 225.A O no hydrogen 3.104 N/A ALA 231.A N VAL 238.A O no hydrogen 2.668 N/A GLU 235.A N ASP 233.A OD1 no hydrogen 3.147 N/A GLY 236.A N ASP 233.A O no hydrogen 2.844 N/A THR 237.A N GLU 159.A OE2 no hydrogen 2.694 N/A VAL 238.A N GLU 159.A OE2 no hydrogen 2.887 N/A THR 239.A N ASN 242.A OD1 no hydrogen 2.946 N/A GLY 241.A N THR 239.A OG1 no hydrogen 3.008 N/A ASN 242.A N THR 239.A OG1 no hydrogen 3.108 N/A ASN 242.A ND2 ASP 173.A OD1 no hydrogen 2.704 N/A ASN 242.A ND2 THR 237.A O no hydrogen 3.338 N/A SER 244.A N ALA 315.A O no hydrogen 2.813 N/A ASN 247.A ND2 GLY 13.A O no hydrogen 3.178 N/A ASP 248.A N GLY 13.A O no hydrogen 3.000 N/A GLY 249.A N GLU 114.A O no hydrogen 2.843 N/A ALA 250.A N THR 10.A OG1 no hydrogen 2.878 N/A ALA 251.A N GLY 112.A O no hydrogen 2.874 N/A ALA 252.A N ALA 8.A O no hydrogen 3.037 N/A LEU 254.A N SER 6.A O no hydrogen 2.931 N/A LEU 255.A N ILE 108.A O no hydrogen 2.698 N/A MET 256.A N VAL 3.A O no hydrogen 2.910 N/A GLU 260.A N SER 257.A OG no hydrogen 3.411 N/A SER 262.A N GLU 258.A O no hydrogen 2.769 N/A ARG 263.A N ALA 259.A O no hydrogen 2.913 N/A ARG 264.A N GLU 260.A O no hydrogen 3.254 N/A ARG 264.A N ALA 261.A O no hydrogen 2.951 N/A GLY 265.A N SER 262.A O no hydrogen 3.106 N/A ILE 266.A N ALA 261.A O no hydrogen 2.943 N/A LEU 269.A N ILE 4.A O no hydrogen 2.547 N/A ARG 271.A N GLU 387.A O no hydrogen 3.248 N/A ILE 272.A N ILE 2.A O no hydrogen 3.069 N/A VAL 273.A N CYS 385.A O no hydrogen 3.086 N/A SER 274.A OG ALA 296.A O no hydrogen 3.412 N/A ALA 276.A N ALA 383.A O no hydrogen 2.649 N/A THR 277.A OG1 GLY 381.A O no hydrogen 2.511 N/A VAL 278.A N GLY 381.A O no hydrogen 3.056 N/A VAL 280.A N GLY 379.A O no hydrogen 2.682 N/A LYS 283.A N ASP 281.A OD1 no hydrogen 2.995 N/A LYS 283.A NZ TYR 150.A OH no hydrogen 2.597 N/A LYS 283.A NZ ASP 281.A OD1 no hydrogen 2.817 N/A LYS 283.A NZ ASP 281.A OD2 no hydrogen 2.858 N/A VAL 284.A N ASP 281.A O no hydrogen 2.788 N/A THR 287.A N VAL 284.A O no hydrogen 3.003 N/A THR 287.A OG1 VAL 284.A O no hydrogen 2.998 N/A GLY 288.A N MET 285.A O no hydrogen 2.888 N/A ILE 290.A N THR 287.A O no hydrogen 3.061 N/A ALA 292.A N GLY 288.A O no hydrogen 3.407 N/A SER 293.A OG PRO 289.A O no hydrogen 2.782 N/A ARG 294.A N PRO 291.A O no hydrogen 3.141 N/A LYS 295.A N PRO 291.A O no hydrogen 3.018 N/A ALA 296.A N ALA 292.A O no hydrogen 3.271 N/A ALA 300.A N LEU 297.A O no hydrogen 2.779 N/A GLY 301.A N GLU 298.A O no hydrogen 2.703 N/A LYS 303.A N ASP 306.A OD2 no hydrogen 2.989 N/A ASP 306.A N LYS 303.A O no hydrogen 2.669 N/A ASP 308.A N LYS 369.A O no hydrogen 2.609 N/A GLU 311.A N LEU 371.A O no hydrogen 2.695 N/A ALA 312.A N ASN 335.A OD1 no hydrogen 2.855 N/A ASN 313.A N THR 373.A O no hydrogen 2.914 N/A ASN 313.A ND2 SER 350.A OG no hydrogen 2.789 N/A ALA 317.A N ASN 242.A O no hydrogen 2.712 N/A GLN 319.A NE2 GLY 286.A O no hydrogen 2.736 N/A ALA 320.A N PHE 316.A O no hydrogen 2.901 N/A CYS 321.A N ALA 317.A O no hydrogen 2.869 N/A CYS 321.A SG GLU 171.A O no hydrogen 3.724 N/A CYS 321.A SG ALA 317.A O no hydrogen 3.328 N/A ALA 322.A N ALA 318.A O no hydrogen 3.342 N/A VAL 323.A N GLN 319.A O no hydrogen 3.114 N/A ASN 324.A N ALA 320.A O no hydrogen 3.320 N/A LYS 325.A N CYS 321.A O no hydrogen 2.964 N/A LYS 325.A NZ GLU 171.A OE1 no hydrogen 3.313 N/A LYS 325.A NZ GLU 171.A OE2 no hydrogen 3.149 N/A LEU 327.A N VAL 323.A O no hydrogen 3.383 N/A SER 332.A N ASP 330.A OD1 no hydrogen 3.110 N/A SER 332.A OG ASP 330.A OD1 no hydrogen 3.123 N/A ILE 333.A N ASP 330.A O no hydrogen 3.088 N/A VAL 334.A N PRO 331.A O no hydrogen 3.253 N/A ASN 335.A N VAL 310.A O no hydrogen 2.923 N/A ASN 335.A ND2 ALA 312.A O no hydrogen 3.390 N/A ASN 335.A ND2 GLU 314.A OE2 no hydrogen 2.870 N/A GLY 338.A N ASN 335.A O no hydrogen 2.940 N/A ALA 340.A N GLU 314.A OE1 no hydrogen 3.490 N/A GLY 344.A N ALA 340.A O no hydrogen 3.018 N/A ALA 345.A N ASN 247.A OD1 no hydrogen 2.660 N/A GLY 348.A N GLU 114.A OE1 no hydrogen 2.719 N/A ALA 349.A N PRO 346.A O no hydrogen 2.979 N/A SER 350.A N PRO 346.A O no hydrogen 2.977 N/A SER 350.A N ILE 347.A O no hydrogen 2.966 N/A ARG 353.A N ALA 349.A O no hydrogen 2.859 N/A ILE 354.A N SER 350.A O no hydrogen 2.766 N/A LEU 355.A N GLY 351.A O no hydrogen 2.899 N/A ASN 356.A N ALA 352.A O no hydrogen 2.874 N/A ASN 356.A ND2 ALA 8.A O no hydrogen 3.481 N/A ASN 356.A ND2 ALA 252.A O no hydrogen 2.941 N/A ASN 356.A ND2 ALA 352.A O no hydrogen 3.656 N/A THR 357.A OG1 GLU 195.A OE1 no hydrogen 3.227 N/A LEU 359.A N LEU 355.A O no hydrogen 2.688 N/A PHE 360.A N ASN 356.A O no hydrogen 3.065 N/A GLU 361.A N THR 357.A O no hydrogen 2.792 N/A MET 362.A N LEU 358.A O no hydrogen 2.846 N/A LYS 363.A N PHE 360.A O no hydrogen 2.841 N/A ARG 364.A N PHE 360.A O no hydrogen 2.717 N/A ARG 364.A N GLU 361.A O no hydrogen 2.870 N/A ARG 364.A NE ASP 194.A OD2 no hydrogen 3.536 N/A ARG 364.A NH1 GLU 361.A OE1 no hydrogen 2.898 N/A ARG 364.A NH2 ASP 194.A OD2 no hydrogen 3.399 N/A ARG 365.A N GLU 361.A O no hydrogen 2.736 N/A ARG 365.A NE GLU 361.A OE2 no hydrogen 2.880 N/A ALA 367.A N MET 362.A O no hydrogen 3.260 N/A LYS 369.A NZ GLU 387.A OE2 no hydrogen 2.742 N/A GLY 370.A N ILE 386.A O no hydrogen 3.397 N/A LEU 371.A N LEU 309.A O no hydrogen 2.746 N/A THR 373.A N GLU 311.A O no hydrogen 2.778 N/A THR 373.A OG1 SER 293.A OG no hydrogen 3.366 N/A THR 373.A OG1 VAL 382.A O no hydrogen 3.495 N/A ILE 376.A N MET 380.A O no hydrogen 2.991 N/A MET 380.A N ILE 376.A O no hydrogen 2.900 N/A ALA 383.A N ALA 276.A O no hydrogen 2.764 N/A CYS 385.A N SER 274.A O no hydrogen 2.597 N/A CYS 385.A SG SER 274.A OG no hydrogen 3.097 N/A CYS 385.A SG ALA 296.A O no hydrogen 3.184 N/A GLU 387.A N ARG 271.A O no hydrogen 3.082 N/A SER 388.A OG MET 362.A O no hydrogen 3.557 N/A SER 388.A OG ALA 367.A O no hydrogen 2.576 N/A